Sample introduction device, sample analysis apparatus, and control method of sample introduction device

文档序号:1009226 发布日期:2020-10-23 浏览:6次 中文

阅读说明:本技术 进样装置、样本分析设备以及进样装置的控制方法 (Sample introduction device, sample analysis apparatus, and control method of sample introduction device ) 是由 孙娟娟 翁彦雯 解传芬 周洋 于 2018-03-16 设计创作,主要内容包括:一种进样装置、样本分析设备以及进样装置的控制方法。将放入单元(100)、缓存单元(200)和回收单元(300)中至少两个相互形成上下层叠结构,利用调度机械手(500)在放入单元(100)、缓存单元(200)、回收单元(300)和吸样区(400)之间传送样本架(600)。可以合理利用竖直方向的空间,在空间上进行叠加,以简化调度流程。同时,减少水平空间的占用,从而减小占地面积,促使装置更小型化。(A sample introduction device, a sample analysis apparatus, and a control method of the sample introduction device. At least two of the input unit (100), the buffer unit (200) and the recovery unit (300) are stacked up and down, and the sample rack (600) is transferred among the input unit (100), the buffer unit (200), the recovery unit (300) and the sample suction area (400) by using the dispatching robot (500). The space in the vertical direction can be reasonably utilized, and superposition can be carried out in the space, so that the scheduling process is simplified. Meanwhile, the occupation of horizontal space is reduced, so that the occupied area is reduced, and the miniaturization of the device is promoted.)

A sample introduction device, comprising:

the device comprises a putting unit, a processing unit and a control unit, wherein the putting unit is used for inputting a sample to be processed;

a cache unit having cache bits for caching samples;

the recovery unit is used for recovering the processed sample, and at least two of the placing unit, the buffer unit and the recovery unit mutually form an up-down laminated structure;

the sample sucking area is used for providing a sample sucking position so that a detection instrument can suck a sample conveniently;

the dispatching manipulator is used for transferring samples among the placing unit, the buffer unit, the recovery unit and the sample sucking area;

and the control unit controls the dispatching manipulator.

The sample introduction device according to claim 1, wherein the input unit and the recovery unit are located above, and the buffer unit is located below.

The sample introduction device according to claim 2, wherein the buffer unit has at least two buffer positions arranged side by side, the input unit and the recovery unit are positioned right above the buffer unit and arranged back and forth along the arrangement direction of the buffer positions, one side of the dispatching manipulator is in butt joint with the input unit and the recovery unit, and the other opposite side of the dispatching manipulator is in butt joint with the sample sucking area.

The sample introduction device according to claim 2, wherein the loading unit and the dispatching manipulator are disposed at two sides of the recovery unit, and the sample suction area is located at a side of the dispatching manipulator far away from the recovery unit.

The sample introduction device according to any of claims 1 to 4, wherein the sample suction region comprises a sample suction transport channel for transporting a sample for suction.

The sample introduction device according to any of claims 1 to 5, wherein the insertion unit comprises a storage device capable of storing at least two sample racks for holding sample containers, the insertion unit has a storage device placement location in which the storage device is removably arranged, and the storage device has a sample outlet for the entry and exit of the sample racks.

The sample introduction device according to claim 6, wherein the storage device placement location is provided with a storage device detection mechanism for detecting whether the storage device is placed.

The sample introduction device according to claim 6 or 7, wherein the introduction unit has an introduction zone push-out mechanism for pushing the sample out of the sample outlet from the storage position of the storage device.

The sample introduction device according to any of claims 6 to 8, wherein each storage device is provided with a put-in area push-back mechanism corresponding to the sample outlet of the storage device, and the put-in area push-back mechanism is used for pushing the sample rack put in the unit back to the storage device or limiting the sample rack in the sample outlet.

The sample introduction device according to any of claims 6 to 9, further comprising a sample output channel, wherein the sample outlet of the storage device is in communication with the sample output channel such that the sample can pass from the sample outlet through the sample output channel and onto the dispatching robot.

The sample introduction device according to claim 10, further comprising a sample introduction pushing mechanism for pushing the sample from the sample outlet onto a dispatching robot along a sample output channel.

The sampling device according to any of claims 1 to 11, wherein the recovery unit comprises a recovery device capable of storing at least two sample holders for holding samples, the recovery device having a recovery port for entry of a sample holder, the recovery unit having a recovery device placement location in which the recovery device is removably disposed.

The sample introduction device according to claim 12, wherein the recovery device placement location is provided with a recovery device detection mechanism for detecting whether the recovery device is placed.

The sample introduction device according to claim 12 or 13, wherein the recovery unit comprises recovery pushing mechanisms, each recovery pushing mechanism corresponding to a recovery port of the recovery device for pushing the recovered sample into the recovery device.

The sample introduction device according to any of claims 12 to 14, further comprising a sample recovery channel, wherein the sample recovery channel is in communication with a recovery port of the recovery device, so that a sample on the dispatching robot can enter the recovery device through the sample recovery channel and the recovery port.

The sample introduction device according to claim 15, further comprising a retrieval pushing mechanism for pushing the sample from the dispatching robot to the retrieval port along the sample retrieval channel.

The sample introduction device according to any of claims 1 to 5, wherein the recovery unit comprises at least two recovery devices, and the introduction unit comprises at least two storage devices, and the recovery devices correspond to the storage devices in number.

The sample introduction device according to any one of claims 1 to 5, wherein a sample access channel is provided between the input unit and the recovery unit, the sample access channel is communicated with both the input unit and the recovery unit, and the dispatching manipulator is capable of docking with the sample access channel for transferring a sample.

The sample introduction device according to claim 18, wherein the sample access channel is provided with a sample access pushing mechanism for pushing the sample out and back into the sample access channel.

The sample introduction device according to any one of claims 1 to 19, further comprising an emergency sample introduction channel, wherein the emergency sample introduction channel is independently provided, and an outlet thereof is provided facing the dispatching robot.

The sampling device according to claim 4, further comprising a scanning unit for scanning the sample, wherein the placing unit is provided with a sample output channel, one end of the sample output channel bypasses the recovery unit and extends to the position of the dispatching manipulator, and the scanning unit is arranged in the sample output channel.

The sample introduction device according to any of claims 1 to 20, further comprising a scanning unit for scanning the sample;

the scanning unit is arranged below the recovery unit and the placing unit and is arranged in parallel with the cache unit in front and at the back;

or the scanning unit is arranged above the buffer unit and is arranged side by side with the recovery unit and/or the putting-in unit.

The sample introduction device according to claim 19, wherein a scanning unit is disposed in the sample access channel for scanning the introduced sample.

The sample introduction device according to any of claims 1 to 23, wherein the dispatching robot comprises a sample rack storage mechanism for storing sample racks for housing sample containers during transport and a dispatching drive mechanism outputting a reciprocating motion in a vertical direction to drive the sample rack storage mechanism at least to be movable in the vertical direction.

The sample introduction device according to claim 24, wherein the buffer unit has at least two buffer positions arranged side by side, and the scheduling driving mechanism outputs a reciprocating motion along an arrangement direction of the buffer positions, so that the sample rack storage mechanism can move to any buffer position, the arrangement direction of the buffer positions is a Y axis, the vertical direction is a Z axis, and the Y axis and the Z axis are perpendicular to each other.

The sample introduction device according to claim 25, wherein the sample rack storage mechanism has a receiving groove matching with the shape of the sample rack, and at least one side of the receiving groove is provided with an opening having a bell mouth shape with a larger outer part and a smaller inner part, so as to facilitate the entry of the sample rack.

The sample introduction device according to claim 25 or 26, wherein the scheduling drive mechanism comprises a first drive mechanism for driving the sample rack storage mechanism to move along the Y-axis and a second drive mechanism for driving the sample rack storage mechanism to move along the Z-axis, wherein the sample rack storage mechanism is mounted on the second drive mechanism, and wherein the second drive mechanism is mounted on the first drive mechanism.

The sample introduction device according to claim 27, wherein the first driving mechanism comprises a first stepping motor and a first timing belt transmission mechanism driven by the first stepping motor, and the second driving mechanism is mounted on a timing belt of the first timing belt transmission mechanism.

The sample introduction device according to claim 27 or 28, wherein the second drive mechanism comprises a second stepper motor and a lead screw and nut mechanism driven by the second stepper motor, the sample rack storage mechanism being mounted on the lead screw and nut mechanism.

The sample introduction device according to any one of claims 26 to 29, wherein the dispatching robot further comprises a pusher dog and a pusher dog driving mechanism for driving the pusher dog to move, wherein the pusher dog driving mechanism outputs reciprocating motion along an X-axis and a Z-axis, the X-axis, the Y-axis and the Z-axis are mutually perpendicular in pairs, and the X-axis is a direction in which the sample rack enters and exits the containing groove, so that the pusher dog can move along the X-axis and the Z-axis to hook or release the sample rack.

The sample introduction device according to claim 30, wherein the pusher has two opposing hooks, and the distance between the hooks is greater than the length of the sample rack.

The sampling device according to claim 30 or 31, wherein the pusher dog is disposed below the receiving groove, an inlet and an outlet are reserved at the bottom of the receiving groove for the pusher dog, and an avoiding port for avoiding the pusher dog is reserved at the bottom of the buffer position of the buffer unit.

The sample introduction device according to any one of claims 30 to 32, wherein the pusher dog driving mechanism comprises a telescopic driving motor and a cam, the cam rotates with an output end of the telescopic driving motor and has a section of closed guide groove, the pusher dog is movably installed in the guide groove, and distances from a groove wall of the guide groove to a rotation center of the cam are different, so that the pusher dog is driven to move telescopically in a rotation process of the cam to form a movement along a Z-axis.

The sample introduction device according to any one of claims 30 to 33, wherein the pusher dog driving mechanism comprises a translational driving motor and a third synchronous belt transmission mechanism, the third synchronous belt transmission mechanism is mounted on the translational driving motor, and the telescopic driving motor and the cam are fixed on a synchronous belt of the third synchronous belt transmission mechanism to form a movement along the X-axis.

The sample introduction device according to any one of claims 30 to 34, wherein the bottom wall and/or the side walls of the receiving chamber are made of rubber to increase friction between the bottom wall and/or the side walls and the sample rack.

The sample introduction device according to any of claims 30 to 35, wherein the side wall of the receiving chamber is provided with a protruding elastic member for applying an elastic force to the sample rack when the sample rack enters the receiving chamber.

The sample introduction device according to any one of claims 30 to 36, wherein the sample rack storage mechanism is provided with a vacancy detection mechanism for detecting whether a sample rack exists in the buffer position of the buffer unit.

A sample analysis apparatus, comprising a sample introduction device according to any of claims 1 to 37 and a detection device for detecting a sample, wherein the detection device is arranged corresponding to a sample suction area of the sample introduction device.

A control method of a sample introduction device is characterized in that the sample introduction device comprises a placing unit for inputting a sample to be processed, a buffer unit for buffering the sample,

the system comprises a recovery unit, a sample suction area, a scheduling manipulator and a control unit, wherein the recovery unit is used for recovering a processed sample, and the scheduling manipulator is used for scheduling the sample;

the control method comprises the following steps:

and (3) conventional sample injection step: after receiving the sample from the putting-in unit, the dispatching manipulator sends the sample to a cache unit for caching or a sample sucking area;

and (3) a recovery step: and the dispatching manipulator sends the sample which finishes the sample suction to a recovery unit for recovery.

The control method of claim 39, wherein the input unit and the recovery unit are located at an upper position, the buffer unit is located at a lower position, and in the normal sample injection step, when the sample needs to be delivered to the buffer unit, the control unit controls the dispatching manipulator to move downwards to deliver the sample to the buffer unit after the dispatching manipulator obtains the sample from the input unit.

The control method of claim 39 or 40, wherein the sample introduction device further comprises a scanning unit;

wherein, the scanning unit and the putting-in unit are arranged above the buffer unit side by side, and the scanning unit is communicated with the sample outlet of the putting-in unit, and the control method further comprises:

a scanning step: the control unit controls the sample output by the putting unit to pass through the scanning unit and scan the sample, and the scanned sample is sent to the dispatching manipulator for dispatching;

or the scanning unit is arranged below the recovery unit and the putting unit and is arranged in parallel with the cache unit front and back, and the control method further comprises the following steps:

a scanning step: when the dispatching manipulator obtains a sample in the sampling process, the control unit controls the dispatching manipulator to move downwards, the sample is sent to the scanning unit for scanning, the scanned sample is sent to the dispatching manipulator, and then the scanned sample is sent to the cache unit or the sample suction area by the dispatching manipulator.

The control method of any one of claims 39-41, wherein the sample introduction device further comprises an emergency channel, the control method further comprising:

emergency sample injection step: when the control unit receives the emergency instruction, the dispatching manipulator is instructed to complete the current working instruction, and then the sample is preferentially obtained from the emergency channel and sent to the sample suction area for sample suction.

The control method according to claim 42, wherein the specimen aspirating region has a specimen aspirating conveying passage for conveying the specimen supplied from the input unit and an emergency specimen aspirating conveying passage for conveying the specimen supplied from the emergency passage in the emergency sample feeding step, and the dispatching robot sends the specimen supplied from the emergency passage to the emergency specimen aspirating conveying passage in the emergency sample feeding step.

The control method according to any one of claims 39 to 43, wherein the input unit has at least two storage devices which can be accessed, and in the normal sample injection step, the control unit judges the number of the storage devices in the input unit; if only one storage device is provided, sampling is carried out from the storage device; if more than two storage devices exist, judging whether an instruction of one storage device for sampling preferentially is received, and if so, preferentially controlling the storage device appointed by the instruction to sample; if not, controlling the storage device to sample according to a preset sequence.

The control method according to claim 44, wherein in the normal sample injection step, the control unit detects whether the number of samples of the storage device currently injected is empty, and if the number of samples of the storage device currently injected is empty, the control unit starts other storage devices to inject samples or sends a signal that the storage device is empty.

The control method according to any one of claims 39 to 45, wherein the recovery unit includes a recovery device capable of storing at least two sample racks, and in the recovery step, the control unit judges the number of recovery devices in the recovery unit; if only one recovery device exists, setting the recovery device to recover the sample; if more than two recovery devices exist, judging whether an instruction that one recovery device preferentially recovers the sample is received, and if so, preferentially controlling the recovery device appointed by the instruction to recover the sample; and if not, controlling the recovery device to recover the samples according to a preset sequence.

The control method of claim 46, wherein in the recovering step, the control unit detects whether the currently operating recovering device is full, and if so, the control unit starts other recovering devices to recover the sample or sends a signal that the recovering device is full.

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