Experimental mouse spinal segment fixing device
阅读说明:本技术 实验小鼠脊椎节段固定装置 (Experimental mouse spinal segment fixing device ) 是由 周凯亮 许聪 盛孙仁 徐晖 徐华梓 于 2020-06-05 设计创作,主要内容包括:本发明公开了一种实验小鼠脊椎节段固定装置,包括固定板,所述固定板端面上开设有容置槽,所述容置槽两侧开设有推移槽,所述推移槽内滑移设置有推移板,所述推移板由横板和竖板组成,所述横板与竖板连接呈“L”型设置,所述竖板与固定板端面垂直设置,所述横板在推移槽中向容置槽方向滑移使得竖板朝容置槽方向聚拢实现两个竖板对小鼠身躯的夹紧,所述推移槽内设置有用于使竖板夹紧小鼠的复位件,所述容置槽内设置有托举气囊,所述固定板内开设有输气管路,所述输气管路一端与托举气囊充气孔连通,另一端穿出固定板与外界充气设备连接,所述固定板上还设置有用于固定小鼠四肢的压紧件,本发明解决了现有技术中无法将小鼠牢牢固定的问题。(The invention discloses a fixing device for spinal segments of experimental mice, which comprises a fixing plate, wherein an accommodating groove is formed in the end surface of the fixing plate, pushing grooves are formed in two sides of the accommodating groove, a pushing plate is arranged in the pushing groove in a sliding manner and consists of a transverse plate and a vertical plate, the transverse plate is connected with the vertical plate in an L-shaped manner, the vertical plate is perpendicular to the end surface of the fixing plate, the transverse plate slides in the pushing groove towards the direction of the accommodating groove to enable the vertical plate to gather towards the direction of the accommodating groove so as to clamp the bodies of the mice, a resetting piece for enabling the vertical plate to clamp the mice is arranged in the pushing groove, a lifting air bag is arranged in the accommodating groove, an air conveying pipeline is arranged in the fixing plate, one end of the air conveying pipeline is communicated with an air filling hole of the lifting air bag, the other end of the air conveying pipeline penetrates through the fixing, the invention solves the problem that the mouse cannot be firmly fixed in the prior art.)
1. An experimental mouse spinal segment fixing device which is characterized in that: comprises a fixing plate for placing a mouse, wherein the end surface of the fixing plate is provided with a containing groove for containing the body of the mouse, the two sides of the containing groove are provided with a pushing groove, a pushing plate is arranged in the pushing groove in a sliding way and consists of a transverse plate and a vertical plate, the transverse plate and the vertical plate are connected in an L-shaped arrangement, the vertical plate is arranged vertically to the end surface of the fixed plate, the transverse plate slides towards the direction of the containing groove in the pushing groove so that the vertical plates are gathered towards the direction of the containing groove to clamp the mouse body by the two vertical plates, a reset piece for enabling the vertical plate to clamp the mouse is arranged in the pushing groove, a lifting air bag is arranged in the containing groove, gas transmission pipeline has been seted up in the fixed plate, gas transmission pipeline one end with lift the gasbag and aerify the hole intercommunication, the other end is worn out the fixed plate and is connected with external inflation equipment, still be provided with the piece that compresses tightly that is used for fixed mouse four limbs on the fixed plate.
2. The experimental mouse spinal level fixation device of claim 1, wherein: the reset piece is reset spring, reset spring sets up in pushing the inslot, reset spring one end is connected with the diaphragm, and the other end and the inner wall connection of pushing the inslot, the diaphragm slides to fixed plate both sides and realizes reset spring's deformation, the diaphragm slides to the storage tank direction and makes reset spring shape resume and realize that two risers press from both sides tight to the mouse body.
3. The experimental mouse spinal level fixation device of claim 1, wherein: the fixing plate is provided with two limit grooves along the length direction of the fixing plate, the two limit grooves are positioned at two sides of the accommodating groove, two sliding grooves are respectively arranged on the inner walls of the two limit grooves, the sliding grooves are arranged along the vertical direction of the end surface of the fixing plate, a sliding block is arranged in the sliding grooves in a sliding manner along the length direction of the sliding grooves, a limit rod is arranged in the limiting groove in a sliding manner, one end of the limit rod penetrates out of the fixing plate and is held by an operator, one end of the sliding block, which penetrates out of the sliding grooves to the end surface of the fixing plate, penetrates into the limit grooves and is abutted against the outer wall of the limit rod, the abutting end is abutted against the outer wall of the limit rod to realize the sliding limit of the sliding block in the sliding grooves, the pressing piece is a pressing plate, the pressing plate is arranged on the sliding end, the pressing plate is arranged in parallel to the end surface of the fixing plate, the pressing plate presses down to tightly press the limbs of the mouse on the end face of the fixing plate to fix the limbs of the mouse, the sliding block is provided with a driving piece used for providing pressing stress for the pressing plate, and the sliding groove is internally provided with a stopping piece used for preventing the sliding block from being separated from the sliding groove.
4. The experimental mouse spinal level fixation device of claim 3, wherein: the driving piece comprises an expansion spring, the expansion spring is arranged in the chute, one end of the expansion spring is fixed on the inner wall of the chute, the other end of the expansion spring is fixedly connected with the abutting end, the abutting end abuts against the outer wall of the limiting rod to achieve contraction of the expansion spring, and the abutting end is inserted into the clamping groove and abuts against the bottom of the clamping groove to achieve restoration of the expansion spring.
5. The experimental mouse spinal level fixation device of claim 3, wherein: the stopping piece comprises a first stopping block and a second stopping block, the first stopping block is arranged on the inner wall of the sliding groove, the first stopping block is arranged close to the opening of the sliding groove, the second stopping block is arranged on the abutting end, and the second stopping block abuts against the first stopping block to realize the separation limit of the sliding block when the sliding block moves upwards in the sliding groove.
6. The experimental mouse spinal level fixation device of claim 3, wherein: the conflict end cross-section is the triangle-shaped setting, the draw-in groove inner wall is provided with the inclined plane, the gag lever post slides at the spacing inslot and makes the inclined plane realize conflict end and break away from the draw-in groove towards the conflict end application of force.
7. The experimental mouse spinal level fixation device of claim 3, wherein: and a soft silica gel pad is arranged on one surface of the pressing plate, which is in contact with four limbs of the mouse.
8. The experimental mouse spinal level fixation device of claim 1, wherein: the end face of the fixed plate is provided with scale strips, and the scale strips are arranged at the edge of the end face of the fixed plate.
9. The experimental mouse spinal level fixation device of claim 1, wherein: and an elastic cushion is arranged on one surface of the vertical plate, which is in contact with the mouse.
Technical Field
The invention relates to the technical field of experimental animal fixing devices, in particular to an experimental mouse vertebral segment fixing device.
Background
The mouse, as an organism with a very high similarity to human genes, is often used in laboratory animal experiments, and because of the high matching between the genes and the human genes, it is often taken by experimenters for drug experiments or anatomical experiments, whereas in the prior art, before anatomical experiments, an operator usually needs to fix the mouse on a plate through an adhesive tape or an elastic band, then the plate and the mouse are taken together to irradiate X-rays, the bone of the mouse can be completely detected through the detection technique of the X-rays, then the operator controls the mouse through an X-ray film, the specific orientation of the bone of the mouse is determined, and then the operator opens the mouse to take out the required spinal segment, whereas in the prior art, the fixing device for fixing the mouse is too crude, and usually four limbs are fixed through elastic bands, however, the body of the mouse still twists on the plate, the spine position that leads to showing on the X-ray film is not matched with the spine position of actual mouse for operating personnel trompil position is incorrect on mouse, leads to the unable smooth cut-off section of taking out the mouse of operating personnel, and need open more wounds on mouse more, causes very big influence to the self-healing in mouse later stage, and has influenced the accuracy of mouse experimental data.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a fixing device for experimental mouse spinal segments, which aims to solve the problem that the mouse cannot be firmly fixed in the prior art.
In order to achieve the purpose, the invention provides a fixing device for experimental mouse vertebral segments, which comprises a fixing plate for placing a mouse, wherein an accommodating groove for accommodating the body of the mouse is formed in the end surface of the fixing plate, pushing grooves are formed in two sides of the accommodating groove, pushing plates are arranged in the pushing grooves in a sliding manner and consist of transverse plates and vertical plates, the transverse plates and the vertical plates are connected and arranged in an L shape, the vertical plates and the end surface of the fixing plate are vertically arranged, the transverse plates slide in the pushing grooves towards the direction of the accommodating groove to enable the vertical plates to be gathered towards the direction of the accommodating groove to clamp the body of the mouse, resetting pieces for enabling the vertical plates to clamp the mouse are arranged in the pushing grooves, lifting air bags are arranged in the accommodating groove, air conveying pipelines are arranged in the fixing plate, one end of each air conveying pipeline is communicated with an air charging hole of each lifting air bag, the other end of each air, the fixing plate is also provided with a pressing piece for fixing four limbs of the mouse.
The technical scheme is adopted, and the method has the advantages that: an operator pushes the two vertical plates towards the directions of the two side edges of the fixed plate, a mouse is flatly laid on the fixed plate, the abdomen of the mouse is tightly attached to the outer surface of the lifting air bag, the four limbs of the mouse are fixed through the compression part, the mouse is fixed on the fixed plate at the moment, then the operator releases the hand held on the vertical plates, the vertical plates move towards the direction of the containing groove because of the driving force of the reset part, the transverse plates slide in the pushing groove, so that the vertical plates finally abut against the waist of the mouse, the two vertical plates are combined to clamp the waist of the mouse, the mouse is prevented from twisting on the fixed plate, the posture of the mouse kept on the fixed plate is ensured to be consistent with the posture of the X-ray sheet, the position of a spinal segment detected on the X-ray sheet is further ensured to be consistent with the position of a spinal segment of the mouse on the fixed plate, and the, the operation personnel can dig and take the mouse vertebral segment conveniently; when an operator needs to dig the lumbar of the mouse, the mouse is tiled on the fixing plate, so that when the operator opens a wound on the mouse, the lumbar of the mouse cannot be completely exposed due to the muscle and the like, the operator can open the external inflation equipment before the operation, the external inflation equipment inflates the gas transmission pipeline, the lifting gas bag inflates and expands the lifting gas bag and pushes the waist and abdomen of the mouse to move upwards, the waist and abdomen of the mouse are lifted by the lifting gas bag, the whole posture of the mouse is in a parabola shape, the operator opens the wound on the mouse, the lumbar of the mouse is completely exposed under the sight of the operator, and the operator can perform an operation experiment on the mouse better; the setting of above-mentioned technique makes things convenient for the experimenter to carry out the experiment more, and ensures that mouse vertebra segment can be taken out smoothly, further accelerates the accuracy of experiment progress and experiment.
The invention further provides that: the reset piece is reset spring, reset spring sets up in pushing the inslot, reset spring one end is connected with the diaphragm, and the other end and the inner wall connection of pushing the inslot, the diaphragm slides to fixed plate both sides and realizes reset spring's deformation, the diaphragm slides to the storage tank direction and makes reset spring shape resume and realize that two risers press from both sides tight to the mouse body.
The technical scheme is adopted, and the method has the advantages that: the piece that resets is reset spring, and when the diaphragm carried out glide movement towards the fixed plate both sides, diaphragm extrusion reset spring made reset spring compression and deformation, and the diaphragm relieved the extrusion to reset spring when the diaphragm was glide movement to the storage tank direction for reset spring shape resumes, and exert the thrust to the diaphragm when the reset spring shape resumes, makes the improvement of two risers to the tight dynamics of mouse body clamp.
The invention further provides that: the fixing plate is provided with two limit grooves along the length direction of the fixing plate, the two limit grooves are positioned at two sides of the accommodating groove, two sliding grooves are respectively arranged on the inner walls of the two limit grooves, the sliding grooves are arranged along the vertical direction of the end surface of the fixing plate, a sliding block is arranged in the sliding grooves in a sliding manner along the length direction of the sliding grooves, a limit rod is arranged in the limiting groove in a sliding manner, one end of the limit rod penetrates out of the fixing plate and is held by an operator, one end of the sliding block, which penetrates out of the sliding grooves to the end surface of the fixing plate, penetrates into the limit grooves and is abutted against the outer wall of the limit rod, the abutting end is abutted against the outer wall of the limit rod to realize the sliding limit of the sliding block in the sliding grooves, the pressing piece is a pressing plate, the pressing plate is arranged on the sliding end, the pressing plate is arranged in parallel to the end surface of the fixing plate, the pressing plate presses down to tightly press the limbs of the mouse on the end face of the fixing plate to fix the limbs of the mouse, the sliding block is provided with a driving piece used for providing pressing stress for the pressing plate, and the sliding groove is internally provided with a stopping piece used for preventing the sliding block from being separated from the sliding groove.
The technical scheme is adopted, and the method has the advantages that: an operator firstly lays a mouse on a fixed plate before an operation, four limbs of the mouse are prevented from being on a pressing plate one by one, then the operator holds and pulls a limiting rod, so that the limiting rod slides in a limiting groove, the collision end is originally collided with the outer wall of the limiting rod, when the limiting rod slides in the limiting groove, the collision end is inserted into a slot, so that a sliding block moves downwards in the sliding groove, the pressing plate moves towards the end face of the fixed plate, namely the pressing plate moves downwards, the pressing plate presses the four limbs of the mouse on the end face of the fixed plate to fix the four limbs of the mouse, the mouse can be better fixed on the fixed plate by the technical arrangement, the spinal segment of the mouse can be more accurately found when the operator performs an experiment, the correctness of the experiment is ensured, the possibility that the mouse moves on the fixed plate is avoided by the technical arrangement, the position of the spinal segment of the mouse in an X-ray sheet is further ensured to be consistent with the spinal segment of the mouse on the fixed, the experiment of the laboratory staff on the mouse is more convenient; and the setting of driving piece is further fixed mouse four limbs on the fixed plate terminal surface, and the setting of preventing the piece can prevent that the slider from breaking away from the spout.
The invention further provides that: the driving piece comprises an expansion spring, the expansion spring is arranged in the chute, one end of the expansion spring is fixed on the inner wall of the chute, the other end of the expansion spring is fixedly connected with the abutting end, the abutting end abuts against the outer wall of the limiting rod to achieve contraction of the expansion spring, and the abutting end is inserted into the clamping groove and abuts against the bottom of the clamping groove to achieve restoration of the expansion spring.
The technical scheme is adopted, and the method has the advantages that: the setting of expanding spring makes the end of keeping to touch can insert the draw-in groove smoothly and realize the clamp plate and push down on the fixed plate terminal surface, ensures that the clamp plate can be normal fix mouse four limbs.
The invention further provides that: the stopping piece comprises a first stopping block and a second stopping block, the first stopping block is arranged on the inner wall of the sliding groove, the first stopping block is arranged close to the opening of the sliding groove, the second stopping block is arranged on the abutting end, and the second stopping block abuts against the first stopping block to realize the separation limit of the sliding block when the sliding block moves upwards in the sliding groove.
The technical scheme is adopted, and the method has the advantages that: when the slider shifts up to the final distance in the spout, the second stop block contradicts with first stop block and realizes breaking away from of slider spacing, ensures that the slider can not break away from the spout when shifting up to the final distance in the spout, avoids the clamp plate to drop from the fixed plate.
The invention further provides that: the conflict end cross-section is the triangle-shaped setting, the draw-in groove inner wall is provided with the inclined plane, the gag lever post slides at the spacing inslot and makes the inclined plane realize conflict end and break away from the draw-in groove towards the conflict end application of force.
The technical scheme is adopted, and the method has the advantages that: conflict end cross-section is triangle-shaped setting, and the draw-in groove inner wall is provided with the inclined plane, and after conflict end inserts the draw-in groove, conflict end hypotenuse department and inclined plane laminating, when the gag lever post slides at the spacing inslot, the inclined plane makes conflict end hypotenuse department and inclined plane dislocation realize that the conflict end breaks away from the draw-in groove to the application of force of conflict end, and when the gag lever post was slided in the spacing groove in the setting of above-mentioned technique, the clamp plate can normally function from top to bottom.
The invention further provides that: and a soft silica gel pad is arranged on one surface of the pressing plate, which is in contact with four limbs of the mouse.
The technical scheme is adopted, and the method has the advantages that: the soft silica gel pad prevents the four limbs of the mouse from being damaged when the pressure plate is used for fixing the four limbs of the mouse.
The invention further provides that: the end face of the fixed plate is provided with scale strips, and the scale strips are arranged at the edge of the end face of the fixed plate.
The technical scheme is adopted, and the method has the advantages that: be provided with the scale strip on the fixed plate terminal surface, and the scale strip is arranged at fixed plate terminal surface edge, take away when shining the X-ray with the mouse when the laboratory technician, the scale strip also can be visited and take notes, make the laboratory technician can come to contrast with the scale strip on the fixed plate according to the position of each spinal column of mouse on the X-ray piece and the position that the festival post corresponds the scale strip, the setting up of above-mentioned technique makes things convenient for the laboratory technician to experiment, it is unanimous with mouse spinal segment on the fixed plate to ensure mouse spinal segment on the X-ray piece, avoid the experiment to make mistakes.
The invention further provides that: and an elastic cushion is arranged on one surface of the vertical plate, which is in contact with the mouse.
The technical scheme is adopted, and the method has the advantages that: be provided with the cushion on the one side of riser and mouse contact, cause the damage to the mouse belly when avoiding the riser extrusion mouse belly.
Drawings
FIG. 1 is a three-dimensional view of the present invention;
fig. 2 is a side cross-sectional view of the present invention.
Detailed Description
The invention provides a fixing device for experimental mouse vertebral segments, which comprises a
An operator pushes the two
While there have been shown and described what are at present considered the fundamental principles and essential features of the invention and its advantages, it will be understood by those skilled in the art that the invention is not limited by the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the invention as defined by the appended claims and their equivalents.
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