阅读说明：本技术 基于协作机器人的***粒子植入系统及方法 (Prostate particle implantation system and method based on cooperative robot ) 是由 张永德 杨健智 左思浩 于 2020-07-09 设计创作，主要内容包括：本发明涉及前列腺微创医疗设备领域,公开了一种基于协作机器人的前列腺粒子植入系统及方法,系统包括工控机、工控机I/O设备、超声探头模组、超声探头传感器、粒子植入模组、粒子植入传感器和控制柜。工控机用于接收、处理、存储和发送控制指令；工控机I/O设备为医生与工控机提供交互通道；控制柜根据控制指令,通过控制总线驱动各执行端的电机运转；超声探头模组提供导航功能；超声探头传感器用于辅助系统完成术前定位初始化；粒子植入模组完成术中具体的植入粒子操作；粒子植入传感器用于检测协作机器人各关节上的受力变化。本发明能减轻医生劳动强度和人力资源压力、保证手术效果,系统中安装的传感器还保证了患者与医生的人身安全。(The invention relates to the field of minimally invasive medical equipment for prostate, and discloses a prostate particle implantation system and method based on a cooperative robot. The industrial personal computer is used for receiving, processing, storing and sending control instructions; I/O equipment of the industrial personal computer provides an interaction channel for a doctor and the industrial personal computer; the control cabinet drives the motors of the execution ends to operate through the control bus according to the control instruction; the ultrasonic probe module provides a navigation function; the ultrasonic probe sensor is used for assisting the system to complete preoperative positioning initialization; the particle implantation module finishes the specific particle implantation operation in the operation; the particle implantation sensor is used for detecting stress changes on each joint of the cooperative robot. The invention can reduce the labor intensity of doctors and the pressure of human resources, ensure the operation effect, and ensure the personal safety of patients and doctors by the sensor arranged in the system.)

1. Prostate particle implantation system based on cooperative robot comprises industrial computer, industrial computer IO equipment, switch board, ultrasonic probe module, ultrasonic probe sensor, particle implantation module and particle implantation sensor, and its characterized in that includes:

the industrial personal computer is used for receiving, processing, storing and sending control instructions;

the I/O equipment of the industrial personal computer provides an interaction channel for a doctor and the industrial personal computer;

the control cabinet drives the motors of the execution ends through the control bus according to the control instruction;

the ultrasonic probe module provides a navigation function; (ii) a

The ultrasonic probe sensor is used for assisting the system to complete preoperative positioning initialization;

the particle implantation module completes specific particle implantation operation in the operation;

the particle implantation sensor is used for detecting stress changes on each joint of the cooperative robot.

2. The cooperative robot-based prostate particle implantation system according to claim 1, wherein the industrial personal computer comprises:

the industrial personal computer consists of an industrial personal computer central processing unit, an industrial personal computer storage module, an industrial personal computer I/O module and an industrial personal computer power supply module;

the storage module of the industrial personal computer has to store the following information before operation: the system comprises a voice characteristic model of a voice control instruction, pictures of a sickbed and a guide plate at different angles, a safety protection response program and a control instruction response program;

besides meeting the traditional input and output interaction mode, the I/O module of the industrial personal computer is also provided with a sound collector and a Bluetooth transmitter so as to assist in realizing the voice control and Bluetooth wireless transmission functions of the prostate particle implantation system.

3. The cooperative robot-based prostate particle implantation system according to claim 1, wherein the control cabinet comprises:

the control cabinet consists of a control cabinet central processing unit, a control cabinet I/O module, a control cabinet power supply module, an external sensor control module and four groups of servo motor drivers;

the connection mode between the control cabinet I/O module and the industrial personal computer I/O module can be wired connection, local area network connection or Bluetooth connection;

The external sensor control module is used for controlling the start and the stop of all external sensors in the prostate particle implantation system;

the four groups of servo motor drivers are respectively used for driving and controlling the robot, the implantation mechanism, the ultrasonic probe and the bearing vehicle.

4. The cooperative robot based prostate particle implantation system according to claim 1, wherein the ultrasound probe module comprises:

the ultrasonic probe module consists of an ultrasonic probe and an ultrasonic probe movement mechanism;

the ultrasonic probe movement mechanism is used for bearing the ultrasonic probe, and in addition, five servo motors are further installed on the ultrasonic probe movement mechanism and respectively provide five movements with different degrees of freedom for the ultrasonic probe, such as ascending and descending, advancing and retreating, upward pitching and downward pitching, left-right rotation and left-right yawing.

5. The cooperative robot based prostate particle implantation system according to claim 1, wherein the ultrasound probe sensor comprises:

the ultrasonic probe sensor belongs to one part of an external sensor module and consists of an ultrasonic sensor and a camera;

the ultrasonic sensor is arranged on the ultrasonic probe movement mechanism and provides a distance measuring function for positioning initialization of the prostate particle implantation system;

The camera belongs to a wide-angle camera, is arranged on the ultrasonic probe motion mechanism, and provides a marking object searching and positioning function for the positioning initialization of the prostate particle implantation system, wherein the marking object is a sickbed and a guide plate.

6. The cooperative robot-based prostate particle implantation system according to claim 1, wherein the particle implantation module comprises:

the particle implantation module consists of a robot and an implantation mechanism;

the robot belongs to a cooperative robot, and in addition, the robot has six rotary joints, and each rotary joint is driven by a servo motor;

the implantation mechanism consists of an implantation mechanism auxiliary module and a particle implanter and is arranged at the tail end of the robot, wherein the implantation mechanism auxiliary module can control the particle implanter to complete four operations of advancing and retreating of an outer particle implantation needle, advancing and retreating of an inner particle implantation needle, changing of the outer particle implantation needle and changing of a magazine, and a servo motor responsible for driving in the control process, the outer particle implantation needle required in device changing and magazine equipment are arranged on the implantation mechanism auxiliary module.

7. The cooperative robot based prostate particle implantation system according to claim 1, wherein the particle implantation sensor comprises:

the particle implantation sensor belongs to one part of an external sensor module and consists of six force sensors, wherein the six force sensors are respectively installed in six rotary joints of the robot, and the functions of mistaken touch judgment and safety detection are provided for the prostate particle implantation system.

8. The method for implanting the prostate particles based on the cooperative robot is characterized by comprising the following steps:

s1, setting the coordinates of the implantation target point of the particles;

s2, installing an implantation mechanism;

s3, initializing a prostate particle implantation system;

s4, judging whether a magazine exists, if not, jumping to S5, and if so, jumping to S6;

s5, installing the magazine, and jumping to S6;

s6, judging whether an outer needle exists, if not, jumping to S7, and if so, jumping to S8;

s7, installing an outer needle, and jumping to S8;

s8, implanting the particles;

and S9, judging whether the operation is finished, if not, jumping to S8, and if so, ending.

9. The cooperative robot based prostate particle implantation method according to claim 8, wherein the system initialization comprises:

The system initialization consists of two parts, namely rough positioning initialization and precise positioning initialization;

the rough positioning initialization belongs to semi-automatic operation, and after a doctor sends a control command of 'system initialization', the subsequent rough positioning initialization operation is completed by the prostate particle implantation system;

the precise positioning initialization is manually performed by a doctor according to the actual body position of the patient and a preoperative planning scheme after the prostate particle implantation system completes the rough positioning initialization.

10. The cooperative robot based prostate pellet implantation method of claim 8, wherein the implanting pellet comprises:

implant the particle can by the robot according to the full-automatic completion of the procedure that sets for in the industrial computer, also can pass through by the doctor the semi-automatic completion particle of robot is implanted through industrial computer IO equipment is progressively controlled, and the in-process of implanting the particle, prostate particle implantation system gets into the safety protection mode to guarantee the security of operation process.

Technical Field

The invention relates to the field of minimally invasive prostate medical equipment, in particular to a system and a method for implanting prostate particles based on a cooperative robot.

Background

According to the relevant data of cancer centers in China, the number of prostate cancer patients in China is rapidly increasing in recent years, so that the research on effective treatment of prostate cancer faces increasingly tense pressure. In addition to prostatectomy, prostate brachytherapy is another commonly used treatment method in current clinical treatment, and in the operation process, a doctor manually controls a radioactive particle implanter according to a real-time image acquired by a transrectal ultrasonic probe, implants radioactive particles into a focus target of a patient, and finally kills cancer cells by utilizing radioactive rays, thereby achieving the purpose of treating the patient with prostate cancer. However, when performing an operation, a doctor needs to perform implantation of radioactive seeds while manually adjusting the position of the ultrasound probe to acquire a real-time image, which means that the brachytherapy of the prostate needs to be performed by multiple doctors in cooperation, and in this process, physical strength of the doctor is seriously consumed and personnel waste is easily caused. In addition, doctors rely heavily on personal experience and imagination during the operation, and the operation effect is difficult to ensure.

In view of the above problems, in the prior art, a computer control system is connected to a conventional motor driving device to control a surgical instrument, so as to assist a doctor in performing a prostate brachytherapy. However, this approach can affect the flexibility of the surgical instrument, and the degree of intelligence and control accuracy of the control system can be limited by the choice of motor drive. In addition, in the prior art, a special prostate particle implantation robot is designed to assist a doctor to complete an operation, but the mode needs to invest more funds to study and design the robot in the early stage, so that the universality is poor, and the economic benefit is low.

Disclosure of Invention

In order to overcome the defects in the prior art, the invention provides the prostate particle implantation system and the method based on the cooperative robot, which not only improve the cooperative performance and the flexibility of an operation control system, but also ensure the universality and the economy of system equipment, reduce the labor intensity of doctors, reduce the pressure of human resources and ensure the operation effect, and in addition, the sensors arranged in the prostate particle implantation system also ensure the personal safety of patients and doctors.

In order to achieve the purpose, the technical scheme of the invention is realized in such a way.

Prostate particle implantation system based on cooperative robot comprises industrial computer, industrial computer IO equipment, switch board, ultrasonic probe module, ultrasonic probe sensor, particle implantation module and particle implantation sensor, and its characterized in that includes:

the industrial personal computer is used for receiving, processing, storing and sending control instructions;

the I/O equipment of the industrial personal computer provides an interaction channel for a doctor and the industrial personal computer;

the control cabinet drives the motors of the execution ends through the control bus according to the control instruction;

the ultrasonic probe module provides a navigation function; (ii) a

The ultrasonic probe sensor is used for assisting the system to complete preoperative positioning initialization;

the particle implantation module completes specific particle implantation operation in the operation;

the particle implantation sensor is used for detecting stress changes on each joint of the cooperative robot.

Preferably, the industrial personal computer comprises:

the industrial personal computer consists of an industrial personal computer central processing unit, an industrial personal computer storage module, an industrial personal computer I/O module and an industrial personal computer power supply module;

the storage module of the industrial personal computer has to store the following information before operation: the system comprises a voice characteristic model of a voice control instruction, pictures of a sickbed and a guide plate at different angles, a safety protection response program and a control instruction response program;

the I/O module of the industrial personal computer can meet the traditional input and output interaction mode, and is also provided with a sound collector and a Bluetooth transmitter for assisting in realizing the voice control and Bluetooth wireless transmission functions of the prostate particle implantation system;

preferably, the control cabinet comprises:

the control cabinet consists of a control cabinet central processing unit, a control cabinet I/O module, a control cabinet power supply module, an external sensor control module and four groups of servo motor drivers;

the connection mode between the control cabinet I/O module and the industrial personal computer I/O module can be wired connection, local area network connection or Bluetooth connection;

The external sensor control module is used for controlling the start and the stop of all external sensors in the prostate particle implantation system;

the four groups of servo motor drivers are respectively used for driving and controlling the robot, the implantation mechanism, the ultrasonic probe and the bearing vehicle;

preferably, the ultrasound probe module comprises:

the ultrasonic probe module consists of an ultrasonic probe and an ultrasonic probe movement mechanism;

the ultrasonic probe movement mechanism is used for bearing the ultrasonic probe, and in addition, five servo motors are further installed on the ultrasonic probe movement mechanism and respectively provide five movements with different degrees of freedom for the ultrasonic probe, such as ascending and descending, advancing and retreating, upward pitching and downward pitching, left-right rotation and left-right yawing.

Preferably, the ultrasonic probe sensor includes:

the ultrasonic probe sensor belongs to one part of an external sensor module and consists of an ultrasonic sensor and a camera;

the ultrasonic sensor is arranged on the ultrasonic probe movement mechanism and provides a distance measuring function for positioning initialization of the prostate particle implantation system;

the camera belongs to a wide-angle camera, is arranged on the ultrasonic probe motion mechanism, and provides a marking object searching and positioning function for the positioning initialization of the prostate particle implantation system, wherein the marking object is a sickbed and a guide plate.

Preferably, the particle implantation module comprises:

the particle implantation module consists of a robot and an implantation mechanism;

the robot belongs to a cooperative robot, and in addition, the robot has six rotary joints, and each rotary joint is driven by a servo motor;

the implantation mechanism consists of an implantation mechanism auxiliary module and a particle implanter and is arranged at the tail end of the robot, wherein the implantation mechanism auxiliary module can control the particle implanter to complete four operations of advancing and retreating of an outer particle implantation needle, advancing and retreating of an inner particle implantation needle, changing of the outer particle implantation needle and changing of a magazine, and a servo motor responsible for driving in the control process, the outer particle implantation needle required in device changing and magazine equipment are arranged on the implantation mechanism auxiliary module.

Preferably, the particle implantation sensor comprises:

the particle implantation sensor belongs to one part of an external sensor module and consists of six force sensors, wherein the six force sensors are respectively installed in six rotary joints of the robot, and the functions of mistaken touch judgment and safety detection are provided for the prostate particle implantation system.

The invention also discloses a prostate particle implantation method based on the cooperative robot, which is characterized by comprising the following steps:

s1, setting the coordinates of the implantation target point of the particles;

s2, installing an implantation mechanism;

s3, initializing a prostate particle implantation system;

s4, judging whether a magazine exists, if not, jumping to S5, and if so, jumping to S6;

s5, installing the magazine, and jumping to S6;

s6, judging whether an outer needle exists, if not, jumping to S7, and if so, jumping to S8;

s7, installing an outer needle, and jumping to S8;

s8, implanting the particles;

and S9, judging whether the operation is finished, if not, jumping to S8, and if so, ending.

Preferably, the system initialization comprises:

the system initialization consists of two parts, namely rough positioning initialization and precise positioning initialization;

the rough positioning initialization belongs to semi-automatic operation, and after a doctor sends a control command of 'system initialization', the subsequent rough positioning initialization operation is completed by the prostate particle implantation system;

the precise positioning initialization is manually performed by a doctor according to the actual body position of the patient and a preoperative planning scheme after the prostate particle implantation system completes the rough positioning initialization.

Preferably, the implant particle comprises:

implant the particle can by the robot according to the full-automatic completion of the procedure that sets for in the industrial computer, also can pass through by the doctor the semi-automatic completion particle of robot is implanted through industrial computer IO equipment is progressively controlled, and the in-process of implanting the particle, prostate particle implantation system gets into the safety protection mode to guarantee the security of operation process.

The invention provides a prostate particle implantation system and a method based on a cooperative robot, wherein the system comprises an industrial personal computer for receiving, processing, storing and sending control instructions, an industrial personal computer I/O device for providing an interactive channel for doctors and the industrial personal computer, a control cabinet for driving motors of all execution ends to operate through a control bus and the control instructions, an ultrasonic probe module for providing an intraoperative navigation function, an ultrasonic probe sensor for assisting the prostate particle implantation system to complete preoperative positioning initialization, a particle implantation module for completing prostate particle implantation and a particle implantation sensor for detecting stress changes on all joints of the cooperative robot. Therefore, the prostate particle implantation system based on the cooperation robot is used in the prostate particle implantation operation, the cooperation and the flexibility of the operation control system are improved, the universality and the economy of equipment are ensured, the labor intensity of doctors is reduced, the pressure of human resources is reduced, the operation effect is ensured, and in addition, the personal safety of patients and doctors is ensured by the sensor arranged in the prostate particle implantation system.

Drawings

For ease of illustration, the invention is described in detail by the following detailed description and the accompanying drawings.

Fig. 1 is a block diagram of a cooperative system for implantation of prostatic particles according to the present invention.

Fig. 2 is a constructional view of the prostate particle implanting system of the present invention.

FIG. 3 is a structural diagram of the ultrasonic navigation device of the present invention.

FIG. 4 is a schematic diagram of an industrial personal computer module of the present invention.

FIG. 5 is a schematic diagram of a control cabinet module of the present invention.

Fig. 6 is a flow chart of key steps in the implantation of prostate particles according to the present invention.

Fig. 7 is a flow chart for initializing the coarse positioning of the prostate particle implantation system of the present invention.

Fig. 8 is a front view of the guide plate of the present invention.

Fig. 9 is a flow chart of the present invention for implanting particles.

Detailed Description

In order to make the technical solutions of the embodiments of the present invention better understood and make the above objects, features and advantages of the present invention more comprehensible, it is described in detail below with reference to the accompanying drawings in the embodiments of the present invention. It is to be understood that the embodiments described are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

As shown in fig. 1, it is a block diagram of the cooperative system for implanting prostate particles of the present invention, which specifically includes:

the industrial personal computer I/O device 1 is used for providing an interaction channel for a doctor and the industrial personal computer 3;

the particle implantation sensor 2 is used for detecting stress changes on each joint of the cooperative robot;

the industrial personal computer 3 is used for receiving, processing, storing and sending control instructions;

the ultrasonic probe sensor 4 is used for assisting the system to complete preoperative positioning initialization;

the particle implantation module 5 is used for completing specific particle implantation operation in an operation;

the control cabinet 6 is used for driving the motors of the execution ends through a control bus in combination with a control instruction;

and the ultrasonic probe module 7 is used for providing an intraoperative navigation function.

In the embodiment of the invention, an industrial personal computer I/O device 1 is bidirectionally connected with an industrial personal computer 3 to provide an interaction channel for a doctor; the industrial personal computer 3 is bidirectionally connected with the control cabinet 6 and is used for transmitting a control instruction to the control cabinet 6 and receiving a pulse signal fed back by the control cabinet 6; the particle implantation module 5 and the ultrasonic probe module 7 both use servo motors, so the control cabinet 6 is in bidirectional connection with the particle implantation module 5 and the ultrasonic probe module 7; the particle implantation sensor 2 is used for detecting stress change information of the particle implantation module 5, so that the particle implantation sensor 2 is connected with the particle implantation module in a one-way mode; the ultrasonic probe sensor 4 is arranged on the ultrasonic probe module 7, and the pose adjustment of the ultrasonic probe module 7 directly influences the detection result of the ultrasonic probe sensor 4, so that the ultrasonic probe sensor 4 is in one-way connection with the ultrasonic probe module 7; the information detected by the particle implantation sensor 2 and the ultrasonic probe sensor 4 is required to be transmitted to the industrial personal computer 3 for information processing, so that the particle implantation sensor 2 and the ultrasonic probe sensor 4 are all in one-way connection with the industrial personal computer.

Preferably, on the basis of the cooperative system module for prostate particle implantation shown in fig. 1, as shown in fig. 2, it is a structural diagram of the system for prostate particle implantation of the present invention, wherein the system module already described in fig. 1 is not described herein again, and besides, it further includes:

the display screen 101 is used for providing a human-computer interaction interface for a doctor and displaying input and output information, wherein the human-computer interaction interface is divided into two parts which are respectively used for displaying the implantation information of the prostate particles and the real-time ultrasonic image;

the mouse 102 is used for completing the clicking operation of various command buttons in the human-computer interaction interface, and can also adjust the implantation path sequence of the prostate particle implantation target point, select the ultrasonic image and perform operations such as amplification, reduction, rotation and the like;

the keyboard 103 is used for setting coordinate information of the implantation target point of the prostate particles;

the robot 501 belongs to a cooperative robot and can complete safe and reliable cooperative tasks with doctors in a certain range, the robot has six rotary joints, each joint is driven by a servo motor, and a matched encoder on each servo motor feeds back the actual rotation angle of the servo motor in the working process in the form of pulse signals;

An implantation mechanism auxiliary module 502 installed at the end of the robot 51, wherein a servo motor responsible for driving the particle implanter 503, a particle implantation outer needle and a magazine required for device replacement are all installed on the implantation mechanism auxiliary module 502;

the particle implanter 503 is installed at the tail end of the implantation mechanism auxiliary module 502 and consists of a particle implantation inner needle, a supporting structure and a guiding structure, and is controlled by the implantation mechanism auxiliary module 502 in the operation process to complete four operations of advancing and retreating the particle implantation outer needle, advancing and retreating the particle implantation inner needle, replacing the particle implantation outer needle and replacing a magazine;

the ultrasonic probe moving mechanism 701 is used for bearing an ultrasonic probe, and five servo motors are arranged on the ultrasonic probe moving mechanism, and respectively provide five movements of ascending and descending, advancing and retreating, upward and downward bending, left and right rotation and left and right yawing on different degrees of freedom for the ultrasonic probe 702;

an ultrasonic probe 702, which is used for probing and scanning the position relationship among the prostate, the particle implantation needle and the radioactive particles when entering the patient through the rectum in the operation of implanting the prostate particles;

the bearing vehicle 8 is used for bearing the particle implantation sensor 2, the ultrasonic probe sensor 4, the particle implantation module 5, the control cabinet 6 and the ultrasonic probe module 7, and the bearing vehicle 8 is also driven by a servo motor and can realize movement and rotation in all directions;

The ultrasonic sensors 9 belong to a part of external sensors, and comprise two ultrasonic sensors in total, are respectively arranged at the left side and the right side of the bearing vehicle 8 and are used for detecting whether people or objects approach the bearing vehicle 8 in the operation process so as to play a role in safety protection;

a hospital bed 10 on which an auxiliary fixing bracket is mounted for assisting a patient to lie in a lithotomy position during an operation;

and the guide plate 11 is arranged on the sickbed 10 and is used for assisting the system to complete positioning initialization before operation and outer needle guiding support in the operation.

In the embodiment of the invention, the display screen 101, the mouse 102 and the keyboard 103 all belong to the components of the industrial personal computer I/O device 1, but it should be understood that the components of the industrial personal computer I/O device 1 are not limited thereto. The input device of the industrial personal computer I/O device 1 can also be a mobile device, a voice controller, a gesture controller, an eyeball controller, a master-slave-hand robot and the like, and the output device of the industrial personal computer I/O device 1 can also be a projector, a mobile device, a loudspeaker and the like.

Further, the robot 501, the implantation mechanism auxiliary module 502 and the particle implanter 503 are all part of the particle implantation module 5, and the particle implantation module 5 is mounted on the rear half of the loading plane of the carrier vehicle 8. In addition, the implantation mechanism assist module 502 and the particle implanter 503 are collectively referred to as an implantation mechanism. During the procedure, the implantation mechanism will be driven by the robot 501 to the initial point of each pre-set implantation path.

Specifically, in the robot 501, a particle implantation sensor 2 is also mounted. The particle implantation sensors 2 are six force sensors in total, and are respectively installed in six rotary joints of the robot 501, when the doctor manually operates and controls the robot 501 to complete the accurate positioning initialization operation, the six force sensors quantitatively detect the force applied by the doctor to the rotary joints of the robot 501, and the auxiliary control machine 3 judges whether the operation of the doctor belongs to the accurate initialization positioning operation or the false touch. In addition, when the particles are implanted during the operation, the force sensor will detect whether a person or object touches the main body of the robot 501, thereby playing a role of safety protection.

Further, the ultrasonic probe moving mechanism 701 and the ultrasonic probe 702 constitute an ultrasonic probe module 7, and the ultrasonic probe module 7 is installed in the front half portion on the bearing plane of the bearing vehicle 8. The front half part is a larger groove, and a certain height is reduced relative to the rear half part on the bearing plane of the bearing vehicle 8.

Specifically, on the basis of the configuration of the prostate particle implantation system shown in fig. 2, as shown in fig. 3, which is a configuration diagram of the ultrasound navigation apparatus of the present invention, it can be seen from fig. 3 that the ultrasound probe sensor 4 is composed of an ultrasound sensor 401 and a camera 402. The ultrasonic sensor 401 is mounted on the ultrasonic probe moving mechanism 701 and is located right below the ultrasonic probe 702, and the ultrasonic sensor 401 is used for assisting in measuring distances between the ultrasonic probe 702 and the patient bed 10 and between the ultrasonic probe 702 and the guide plate 11 when the prostate particle implantation system is initialized in positioning. The camera 402 belongs to a wide-angle camera, is mounted on the ultrasonic probe moving mechanism 701, is located right above the ultrasonic probe 702, and is used for shooting a real-time scene when the prostate particle implantation system is initialized to be positioned, and assists the prostate particle implantation system to complete a function of finding and positioning a marker object, wherein the marker object is a hospital bed 10 and a guide plate 11.

Preferably, on the basis of the structure of the prostate particle implantation system shown in fig. 2, as shown in fig. 4, the system is a schematic diagram of an industrial personal computer module of the present invention, and specifically includes:

the industrial personal computer power supply module 301 is used for providing electric energy for the industrial personal computer 3 and the industrial personal computer I/O equipment 1, and has a power-off protection function;

An industrial personal computer storage module 302 for storing data information received and generated by the industrial personal computer 3 during the preoperative, intraoperative and postoperative periods;

an industrial personal computer central processing unit 303, which is used for processing various signals received by the prostate particle implantation system and outputting the processed signals according to a preoperative set control instruction response program;

the industrial personal computer I/O module 304 is used for connecting with the industrial personal computer I/O equipment 1, receiving external control instructions and outputting interactive information;

in the embodiment of the invention, the storage module 302 of the industrial personal computer needs to store the following information before the operation: the system comprises a voice characteristic model of a voice control instruction, pictures of the hospital bed 10 and the guide plate 11 at different angles, a safety protection response program and a control instruction response program. In operation, the storage module 32 of the industrial personal computer also stores the control instruction input by the doctor in real time and the data processing result of the central processor 33 of the industrial personal computer. It should be understood that such pre-operative stored information is not representative of all stored information.

Specifically, the speech feature model of the speech control command must include a speech feature model of the "system initialization" speech control command, and the speech feature model belongs to a non-specific human voice speech feature model.

Further, the pictures of the hospital bed 10 and the guide plate 11 at different angles are mainly divided into two parts: a picture of a patient bed 10 and a picture of a guide plate 11, wherein the picture of the patient bed 10 is taken around the patient bed 10 and 360 degrees, and the picture of the patient bed 10 comprises a flat view, a top view and a bottom view. The guide plate 11 picture is taken around the guide plate 11, 360, and the guide plate 11 picture includes a plan view, a top view and a bottom view.

Further, when the ultrasonic sensor 9 or the particle implantation sensor 2 returns a warning message, the safety protection response program will immediately and automatically respond, stopping the operation and withdrawing the implantation mechanism with the fixed end of the robot 51 from the patient.

Furthermore, the I/O module 34 of the industrial personal computer can satisfy the traditional input/output interaction mode, and is also provided with a sound collector and a bluetooth transmitter for assisting in implementing the voice control and bluetooth wireless transmission functions of the prostate particle implantation system.

Preferably, based on the configuration of the prostate particle implantation system shown in fig. 2, as shown in fig. 5, the system is a schematic diagram of a control cabinet module of the present invention, and specifically includes:

An external sensor control module 601 for controlling the activation and deactivation of the particle implantation sensor 2, the ultrasonic probe sensor 4 and the ultrasonic sensor 9 in the prostate particle implantation system;

the control cabinet power module 602 is used for providing electric energy for the control cabinet 6 and has a power-off protection function;

the control cabinet central processing unit 603 is used for reading and identifying the control instruction transmitted by the industrial personal computer 3 and transmitting the control instruction to a corresponding execution end through a control bus;

the control cabinet I/O module 604 is used for receiving a control signal sent by the industrial personal computer 3 and feeding back an execution result of the control cabinet 6 to the industrial personal computer 3;

a robot motor driver 605 for driving and controlling six servo motors installed in the robot 501, receiving feedback information of encoders in the servo motors, and adjusting driving control of the servo motors according to the feedback information;

an implantation mechanism motor driver 606 for driving the four servo motors installed in the implantation mechanism auxiliary module 502, receiving feedback information of the encoders in the servo motors, and adjusting drive control of the servo motors according to the feedback information;

an ultrasonic probe motor driver 607 for receiving feedback information of an encoder in the five servo motors installed in the ultrasonic probe moving mechanism 701 and adjusting drive control of the servo motors according to the feedback information;

And the motor driver 608 of the carrier vehicle is used for driving and controlling the four servo motors installed in the carrier vehicle 8, receiving feedback information of the encoders in the servo motors, and adjusting the driving and controlling of the servo motors according to the feedback information.

In the embodiment of the present invention, the connection between the control cabinet I/O module 604 and the industrial personal computer I/O module 304 may be wired connection, local area network connection or bluetooth connection;

further, angular displacement information of the servo motors acquired by all encoders in the control cabinet 6 is transmitted to the corresponding drivers, and the drivers adjust the movement of the servo motors according to the received angular displacement information;

specifically, the angular displacement information is also fed back by the driver and transmitted to the control cabinet central processor 63, and after receiving the angular displacement information, the central processor 603 invokes the control cabinet I/O module 604 and transmits the angular displacement information to the industrial personal computer 3, thereby forming a closed-loop system.

As shown in fig. 6, is a flow chart of key steps of the implantation of prostate particles of the present invention, which specifically includes:

s1, setting the coordinates of the implantation target point of the particles;

s2, installing an implantation mechanism;

S3, initializing a prostate particle implantation system;

s4, judging whether a magazine exists, if not, jumping to S5, and if so, jumping to S6;

s5, installing the magazine, and jumping to S6;

s6, judging whether an outer needle exists, if not, jumping to S7, and if so, jumping to S8;

s7, installing an outer needle, and jumping to S8;

s8, implanting the particles;

and S9, judging whether the operation is finished, if not, jumping to S8, and if so, ending.

In the embodiment of the present invention, in step S1, the coordinates of the target point of implantation of the particle are determined according to the medical image data by the physician during the preoperative planning. The doctor classifies a series of determined coordinates of the particle implantation target points, further determines a particle implantation path according to a classification result, sets coordinate information of the prostate particle implantation target points and the prostate particle implantation path in a man-machine interaction interface of the display screen 11 through the I/O equipment 1 of the industrial personal computer, adjusts the implantation sequence of the prostate particle, and stores the implantation path and the implantation sequence in the storage module 302 of the industrial personal computer.

Further, the installation of the implantation mechanism in step S2 is mainly divided into three parts: firstly, a doctor manually operates an implantation mechanism auxiliary module 502 to install the implantation mechanism auxiliary module at the tail end of the robot 501; then, the doctor determines the number of the particle implantation outer needles required for replacing the particle implantation outer needles and the number of the magazines required for replacing the magazines according to the number of the particle implantation paths and the number of the particles obtained by preoperative planning, and uniformly installs the required particle implantation outer needles and the magazines in the implantation mechanism auxiliary module 502, wherein the particles filled in each magazine are manually filled by the doctor, and the filling number is fixed to ten particles; finally, the physician installs the seed implanter 503 on the implantation mechanism assist module 502.

Further, step S4 is to determine whether the prostate particle implantation system is installed with a magazine; the specific judgment method is that the whole stress of the robot 501 changes before and after the magazine is installed, and then the particle implantation sensors 2 installed on the joints of the robot 501 are used for detecting the change of the stress so as to judge.

Further, step S6 is to determine whether the prostate particle implantation system is installed with a particle implantation external needle; the specific judgment method is that the whole stress of the robot 501 changes before and after the implantation of the particle implantation external needle is installed, and then the particle implantation sensors 2 installed on each joint of the robot 501 are used for detecting the change of the stress so as to judge.

Preferably, on the basis of the flow of the key steps of the implantation of prostate particles shown in fig. 6, as shown in fig. 7, it is a flow chart of the initialization of the rough positioning of the implantation system of prostate particles of the present invention, which further includes:

s31, starting the system initialization;

s32, resetting the ultrasonic probe module and the particle implantation module;

s33, enabling the bearing vehicle to rotate, and enabling the camera to acquire a real-time scene;

s34, determining the position of the patient bed according to the scene image;

s35, carrying out ultrasonic ranging, wherein the carrying vehicle moves to a specified distance towards the sickbed;

S36, the carrier vehicle rotates around the sickbed, and the camera acquires a real-time scene;

s37, determining the position of the guide plate according to the scene image;

s38, carrying out ultrasonic ranging, wherein the carrier vehicle moves to a specified distance towards the guide plate;

s39, initializing the poses of the ultrasonic probe module and the particle implantation module;

in the embodiment of the present invention, before starting step S31, the carrying vehicle 8 should have a certain distance from the patient bed 10, where the distance should satisfy that the camera 402 can use the wide-angle technology to shoot the complete patient bed 10, otherwise, if the carrying vehicle 8 is too close to the patient bed 10, the carrying vehicle is not beneficial to the subsequent identification of the industrial personal computer 3 on the patient bed 10 with the marked object.

Further, the system initialization in step S31 may be initiated by the doctor clicking an initialization button of the human-computer interface on the display screen 101 using the mouse 102, or by the doctor issuing a "system initialization" voice control command. When the industrial personal computer 3 receives a system initialization instruction, an execution control instruction response program is called, the control instruction response program is sent to the control cabinet 6, the control cabinet 6 transmits the execution instruction in the control instruction response program to the corresponding execution end through the control bus according to the content in the control instruction response program, and at this time, the prostate particle implantation system starts to perform rough positioning initialization. In addition, the control instructions used in the rough positioning initialization are all stored in the control instruction response program of the industrial personal computer storage module 302 before the operation, and the relevant operations can be completed by calling and executing the control instruction response program.

Further, in step S32, the ultrasonic probe module 7 and the particle implantation module 5 are reset to prevent the positions of the ultrasonic probe module 7 and the particle implantation module 5 from affecting the rough positioning initialization. The reset instructions of the ultrasonic probe module 7 and the particle implantation module 5 are stored in the control instruction response program of the industrial personal computer storage module 32 before the operation, and in addition, the ultrasonic probe sensor 4 carried on the ultrasonic probe module 7 is reset along with the reset instructions when the ultrasonic probe module 7 is reset.

Further, after step S32 is completed, in step S33, the carriage 8 is driven and controlled by the industrial personal computer 3 and the control cabinet 6 to rotate, and at the same time, the camera 402 is driven and controlled by the industrial personal computer 3 and the control cabinet 6 to photograph a real-time scene around the carriage 8.

Further, in step S34, the camera 402 transmits the acquired real-time scene around the carrying vehicle 8 to the industrial personal computer 3, and the industrial personal computer 3 determines the patient bed 10 as the landmark object in the real-time scene picture by combining the stored patient bed 10 picture, and further infers the spatial position of the patient bed 10 relative to the carrying vehicle 8. In addition, the prostate particle implantation system will orient the ultrasonic probe sensor 4 to the front of the carrier vehicle 8, and the industrial personal computer 3 and the control cabinet 6 will adjust the posture of the carrier vehicle 8 relative to the hospital bed 10 according to the real-time scene picture until the front of the carrier vehicle 8 faces the hospital bed 10.

Further, in step S35, the distance between the cart 8 and the bed 10 is measured using the ultrasonic sensor 401 mounted on the ultrasonic probe sensor 4. The industrial personal computer 3 and the control cabinet 6 drive and control the carrier vehicle 8 to move to a specified distance with the sickbed 10 by combining the distance and the control instruction response program. The designated distance is set by the doctor in the control instruction response program, but it should be noted that the designated distance should satisfy the requirement that the camera 402 can photograph one third of the main structure including the patient bed 10. Further, the specified distance should be a range in consideration of the measurement error of the ultrasonic sensor 401.

Further, in step S36, the industrial personal computer 3 and the control cabinet 6 drive and control the carrier vehicle 8 to rotate around the patient bed 10, the distance between the carrier vehicle 8 and the patient bed 10 is not changed during the rotation, and at the same time, the camera 402 is controlled by the industrial personal computer 3 and the control cabinet 6 to photograph the real-time scene of the landmark object patient bed 10.

Further, in step S37, the camera 402 transmits the acquired real-time scene of the landmark object patient bed 10 to the industrial personal computer 3, and the industrial personal computer 3 determines the position of the landmark object guide plate 11 in the patient bed 10 in the real-time scene picture and the spatial position of the landmark object guide plate 11 relative to the carrier vehicle 8 by combining the stored guide plate 11 picture; in addition, the industrial personal computer 3 and the control cabinet 6 adjust the pose of the carrier vehicle 8 relative to the guide plate 11 according to the real-time scene picture until the front face of the carrier vehicle 8 faces the guide plate 11.

Further, in step S38, the ultrasonic sensor 401 mounted on the ultrasonic probe sensor 4 is activated to measure the distance between the vehicle 8 and the guide plate 11. The industrial personal computer 3 and the control cabinet 6 drive and control the carrier vehicle 8 to move beyond the specified distance of the guide plate 11 in combination with the distance and the control instruction response program, wherein the specified distance is set by the doctor in the control instruction response program, but it should be noted that the specified distance should satisfy the requirement that the camera 402 can photograph the complete guide plate 11, and the specified distance should be a range in consideration of the measurement error of the ultrasonic sensor 401.

Further, in step S39, the industrial personal computer 3 and the control cabinet 6 drive the carriage 8 to approach the guide plate 11, and at the same time, the industrial personal computer 3 and the control cabinet 6 control the movement of the ultrasonic probe movement mechanism 701, so that the camera 402 mounted on the ultrasonic probe movement mechanism 701 can acquire a plan view of the front structure view of the guide plate 11. Fig. 8 shows a front structure of the guide plate 11. By comparing the pictures of the guide plate 11 stored in the storage module 302 of the industrial personal computer, when the industrial personal computer 3 knows that the plan view of the front structure diagram of the guide plate 11 acquired by the camera 402 just fills the visual field of the camera 402, the industrial personal computer 3 and the control cabinet 6 stop the movement of the carrier vehicle 8 and the ultrasonic probe movement mechanism at the same time. At this time, the optical center of the camera 402 is on the same horizontal axis as the axis 905 of the guide plate 11 in the guide direction.

Specifically, in the guide plate front structure diagram shown in fig. 9, a mark line 901, a mark line 902, and a mark line 903 are added to the guide plate 11, and when the optical center of the camera 402 is on the same horizontal axis as an axis 905 of the guide plate 11 in the guide direction, the industrial personal computer 3 identifies the mark line 901, the mark line 902, and the mark line 903 from the acquired real-time scene picture, and identifies a rectangular center 904 in a minimum rectangular area surrounded by the mark line 901, the mark line 902, and the mark line 903. Then, the industrial personal computer 3 and the control cabinet 6 adjust the pose of the ultrasonic probe 702 according to the linear distance between the rectangular center 904 and the axis 905 of the wire guide plate in the guide direction and the linear distance between the optical center of the camera 402 and the horizontal long axis of the ultrasonic probe 702, so that the horizontal long axis of the ultrasonic probe 702 and the rectangular center 904 are on the same horizontal axis. Meanwhile, the industrial personal computer 3 and the control cabinet 6 also adjust the pose of the particle implantation module 5, so that the horizontal long axis of the particle implantation inner needle on the particle implanter 503 is on the same horizontal axis with the axis 905 of the guide plate 11 in the guide direction. In the process of adjusting the pose of the particle implantation module 5, it is only required to ensure that the horizontal long axis of the particle implantation inner needle on the particle implanter 503 and the axis 905 of the guide plate 11 in the guide direction are on the same horizontal axis and the particle implantation module 5 does not collide and interfere with the outside, and the pose adjustment control program of the particle implantation module 5 is also compiled by a doctor according to a preoperative planning scheme and stored in the control instruction response program of the storage module 302 of the industrial personal computer.

Further, when step S39 is completed, the coarse positioning initialization of the prostatic particle implantation system is completed, but the prostatic particle implantation system automatically enters the fine positioning initialization stage to compensate for the positioning deviation caused by the patient displacement.

Specifically, when the prostate particle implantation system enters the accurate positioning initialization phase, the particle implantation sensor 2 will be activated, and the particle implantation module 5 and the ultrasonic probe module 7 enter the teaching mode. In the teaching mode, the doctor can manually adjust the poses of the seed implanting module 5 and the ultrasonic probe module 7, place the ultrasonic probe 702 at the patient's rectum, and adjust the seed implanting needle on the seed implanter 503 to the initial point position of the first seed implanting path. In the manual adjustment process of a doctor, the position change of the particle implantation module 5 and the ultrasonic probe module 7 relative to the rough positioning initialization is regarded as a positioning error by the industrial personal computer 3, and the particle implantation target point and the particle implantation path set in the control instruction response program are corrected according to the positioning error.

Preferably, on the basis of the flow of the key step of implanting prostate particles shown in fig. 6, as shown in fig. 9, it is a flow chart of implanting particles of the present invention, which specifically further includes:

S801, enabling an outer needle to enter a focus of a patient along a particle implantation path;

s802, judging whether particles exist in the magazine or not, if so, executing a step S804, otherwise, executing a step S803;

s803, the magazine is replaced, and then step S804 is executed;

s804, the inner needle pushes the particles to enter a focus target point;

s805, withdrawing the inner needle from the patient;

s806, judging whether the implantation of the particles in the same implantation path is finished, if so, executing the step S808, otherwise, executing the step S807;

s807, the outer needle retreats in the patient body by a specified distance, and then the step S802 is returned to;

s808, withdrawing the outer needle from the patient;

s809, judging whether the implantation of the particles is finished, if so, finishing the implantation of the particles, otherwise, executing the step S810;

s810, replacing the outer needle, and then executing the step S811;

s811, the end effector moves to the start of the next implantation path, and then step S801 is performed.

In the embodiment of the invention, before starting to implant the particles, a doctor can set the working mode of the prostate particle implantation system through the industrial personal computer I/O device 1, the implantation can be completed by the robot 501 fully automatically according to a set program, and the implantation can also be completed by the doctor semi-automatically operating the robot 501 step by step through the industrial personal computer I/O device 1.

Further, in step S804, when the first radioactive seeds are implanted, the system defaults to the presence of the seeds in the magazine because the installation of the magazine and the loading of the seeds in the magazine are manually performed by the physician before the operation. However, after the implantation of the first radioactive particle, the industrial personal computer 3 counts the number of particles consumed in the implantation process, and since only ten particles are loaded in each magazine, when the industrial personal computer 3 counts that the ten-time implantation of the particles is completed in the operation, a prompt is sent out in the human-computer interaction interface of the display screen 11, and the magazine replacement is automatically completed by combining with the control cabinet 6.

Further, in step S806, it is determined whether the implantation of the particles in the same implantation path is completed, and the industrial personal computer 3 is required to perform autonomous determination according to the planned particle implantation target and the implantation path.

Further, in step S807, the outer needle is retracted in the patient by a predetermined distance, which is the distance between two particles arranged in the same implantation path.

Further, in the whole particle implantation process, the driving control of the particle implantation module 5 is completed by the industrial personal computer 3 according to a set control instruction, and the ultrasonic probe module 7 is subjected to follow-up control by the industrial personal computer 3 according to the actual motion condition of the particle implantation module 5.

Further, throughout the implantation of the prostate seed, the prostate seed implantation system will enter a safety warning state. At this moment, when the outside has people or thing to be close to and bears the weight of car 8, install ultrasonic sensor 9 who bears the weight of car 8 both sides and will survey the distance between bearing the weight of car 8 and the doctor, when the distance surpassed the safe distance of setting for in the safety protection response procedure, industrial computer 3 will send alarm information, and particle implantation module 5 and ultrasonic probe module 7 will stop working to withdraw from patient's internal. In addition, when a person or an object touches the robot 51, the particle implantation sensor quantitatively detects stress changes of all joints of the robot 51, when the stress changes of all joints of the robot 51 exceed a safety value set in a safety protection response program, the industrial personal computer 3 also sends out alarm information, and the particle implantation module 5 and the ultrasonic probe module 7 also stop working and exit from the patient.

In conclusion, according to the prostate particle implantation system and method based on the cooperative robot provided by the invention, doctors can complete the prostate particle implantation operation together with the cooperative robot, the operation process is simple and convenient, the operation effect is stable and reliable, one doctor can complete the prostate particle implantation operation at the same time, the workload of the doctor is reduced, the pressure of human resources is reduced, and the positioning initialization method in the prostate particle implantation system is added, so that the positioning process of the system is simple and rapid, a doctor does not need to move surgical instruments, only the auxiliary system needs to finish the correction of positioning errors to a certain degree, a sensor is additionally added in the system, the personal safety of the patient and the doctor in the operation process is ensured, and in addition, the cooperation robot also improves the cooperation and flexibility of the operation control system and ensures the universality and economy of system equipment.

The foregoing is a more detailed description of the invention in connection with specific embodiments thereof, and the specific embodiments thereof are not to be considered as limited by the foregoing description. For a person skilled in the art, several non-inventive variants or alterations without departing from the inventive concept should be considered as being within the scope of protection determined by the claims as filed.