阅读说明：本技术 包含反式-1-氯-3,3,3-三氟丙烯的个人护理组合物和方法 (Personal care compositions and methods comprising trans-1-chloro-3, 3, 3-trifluoropropene ) 是由 安东尼·安扎隆 乔恩·托马斯·赫德莱因 凌耀强 于 2018-12-28 设计创作，主要内容包括：本发明公开了包含或使用凝胶、洗剂、霜剂等的个人护理制剂、个人护理方法和个人护理装置,该凝胶、洗剂、霜剂等包含：(a)对人的皮肤和/或毛发和/或粘膜具有有益效果的一种或多种活性成分；以及(b)约1重量％至约50重量％的泡沫形成组分,该泡沫形成组分包含反式-1-氯-3,3,3-三氟丙烯(1233zd(E))。(Disclosed are personal care formulations, methods of personal care and personal care devices comprising or using a gel, lotion, cream or the like comprising: (a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes; and (b) from about 1% to about 50% by weight of a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)).)

1. A method of treating human skin, hair and/or mucous membrane comprising:

(a) providing a personal care composition in the form of a gel, lotion or cream comprising: (i) one or more active ingredients; (ii) optionally one or more auxiliary gel, lotion or cream forming components; and (iii) a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e));

(b) spreading the gel, lotion or cream on and/or into the skin, hair and/or mucous membrane of the person being treated; and

(c) foaming the gel, lotion or cream by allowing the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (E)) to evaporate from the gel, lotion or cream during delivery and/or upon contact with the skin, hair and/or mucosa.

2. The method of claim 1, wherein the personal care composition comprises one or more auxiliary gel, lotion, or cream forming components.

3. The method of claim 1, wherein said foaming step comprises spreading said gel, lotion, cream, and/or foam on and/or into said skin, hair, and/or mucosa of said person being treated, and wherein said spreading provides energy for said evaporation of said 1233zd (e).

4. The method of claim 1, wherein the personal care composition further comprises trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)).

5. A personal care formulation for treating the skin, hair and/or mucous membranes of a person, the personal care formulation including a gel, lotion, cream, etc., comprising:

(a) one or more active ingredients having a beneficial effect on the skin and/or hair and/or mucous membranes of said person,

(b) optionally one or more auxiliary gel, emulsion or cream-forming components, and

(c) from about 1% to about 50% by weight of a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation.

6. The personal care composition of claim 5, wherein the foam forming component comprises the 1233zd (E) and trans-1, 3,3, 3-tetrafluoropropene (1234ze (E)).

7. The personal care composition of claim 6, wherein the weight ratio of 1234ze (E) to the 1233zd (E) is from about 90:10 to about 50: 50.

8. The personal care composition of claim 5, wherein the foam-forming component consists essentially of from about 3 to about 6 weight percent of the 1233zd (E), based on the weight of the components in the personal care composition.

9. A method of treating a person's skin, hair and/or mucous membrane with a personal care gel, lotion, cream or foam, the method comprising:

(a) providing a closed container capable of being opened to dispense its contents and containing therein a personal care formulation in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on the skin and/or hair of said person,

(ii) optionally one or more auxiliary gel, lotion or cream forming components,

(iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of the components (i), (ii), and (iii), the foam-forming component comprising:

(1) from about 5% to about 100% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and optionally

(2) From about 50% to about 95% by weight, based on the total amount of components (1) and (2), of a co-blowing agent other than the 1233zd (e); and

(iv) optionally an external propellant for providing a force tending to expel the personal care composition from the container,

(b) dispensing the personal care formulation from the container by advancing the personal care formulation from the container;

(c) applying the dispensed personal care formulation to the skin, hair and/or mucous membrane; and

(d) after the dispensing step, providing a cooling sensation to the person being treated by evaporating at least a portion of the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) from the coated personal care composition.

10. The method of claim 9, wherein the dispensing step initiates foaming of the personal care formulation.

Technical Field

The present invention relates to personal care compositions and to methods and devices for providing personal care, including but not limited to compositions, articles, and methods relating to post-use foaming effects.

Background

Personal care compositions such as skin lotions, cleansers, and shaving creams (including foams and gels) typically contain several components in addition to the active ingredients. Such additional ingredients may include, for example, thickeners, suspending agents, surfactants, and foaming agents, which are included to achieve the properties of the composition when it is dispensed and/or when applied to the skin.

One particular type of formulation is a gel that self-foams when dispensed and/or when rubbed into or onto an area of skin or scalp being treated. For example, one of the more popular forms of personal care products in use today is a post-foaming shave gel. In such post-foaming compositions, soaps, surfactants, active ingredients, and other components having relatively volatile hydrocarbons are typically added to form a clear, stable gel or emulsion when held under pressure. Once these materials are dispensed and mechanically agitated, the gel forms a foam, typically due to the addition of energy to the gel after dispensing.

Applicants have recognized that existing personal care formulations (including post-foaming and non-post-foaming formulations) lack performance and/or can be improved in several ways. For example, applicants have found that in many existing formulations, the volatile hydrocarbons heretofore used to form foam in post-foaming applications cause deterioration in other desirable aspects of the formulation. For example, applicants have recognized that such prior post-foaming formulations generate foam too quickly upon application, which tends to negate the ability of the formulation to spread on and/or penetrate into the skin/hair of the user to the degree desired by the user. Furthermore, even if existing post-foaming formulations are capable of spreading to a relatively small extent over the skin prior to foaming, such formulations do not enhance or improve the ability of the active ingredient to penetrate into the pores of the skin, thereby providing a perception and improved performance.

Another aspect of the existing formulations is the ability to provide a cooling sensation to the user as a result of the application of the personal care product to the skin and/or hair. In many existing formulations, this sensation is provided by the inclusion of certain components, known as sensates, that control the Transient Receptor Potential (TRP) channels contained in human tissues. See, for example, US 2017/0000713. Applicants have recognized that the use of such sensate ingredients may have several disadvantages, including the relatively high cost of these ingredients and their derivatives. Another potential drawback is the need for the sensate to interact directly with the biological function of the user, which may be undesirable in certain situations/applications, such as users who may be particularly sensitive and/or allergic to direct biological interaction and may experience more persistent side effects as the ingredients remain in contact with the user. Applicants have therefore recognized the need to achieve this cooling sensation using a simpler and less costly mechanism and without the above-mentioned other disadvantages of sensates. Furthermore, applicants have recognized that many users desire to experience a cooling sensation that occurs substantially immediately after application to the skin/hair/mucous membranes, and that these sensates have limited use in those skin, body and mucous membrane applications where a noticeable immediate cooling sensation is desired. Furthermore, applicants have recognized the advantages of treatment compositions and methods wherein the cooling effect is long lasting and preferably also perceived as providing a substantially immediate cooling sensation upon application.

Disclosure of Invention

Applicants have recognized that the use of the methods, articles, and personal care formulations according to the present invention may reduce or substantially eliminate one or more, and preferably all, of the above-described disadvantages and failures associated with existing formulations and methods.

The present invention includes a method of treating human skin, hair and/or mucous membranes comprising:

(a) providing a personal care composition in the form of a gel, lotion or cream or the like comprising: (i) one or more active ingredients; (ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components; and (iii) a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e));

(b) spreading the gel, lotion or cream on and/or into the skin, hair and/or mucous membrane of the person being treated; and

(c) foaming the gel, lotion or cream by allowing the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) to evaporate from the gel, lotion or cream during delivery and/or upon contact with skin, hair and/or mucosa.

It will be appreciated by those skilled in the art that the ingredients used to form the gel, lotion or cream may themselves be considered to have an active function in the sense that they provide the desired effect on the skin, hair or mucous membranes. For example, skin conditioning agents may be in the form of a cream, which is itself considered to be the active ingredient of the formulation. Thus, the term "auxiliary gel, lotion or cream forming component" is used herein to identify an ingredient contained in a formulation whose primary purpose is not to improve the skin or hair, such as to affect the viscosity, feel, texture, delivery properties, etc. of the formulation.

As used herein, the term "foaming the gel, lotion or cream" and similar terms refer to at least a substantial portion of the gel, lotion, cream, etc. being foamed. Thus, the term includes within its meaning a step in which some portion of the gel, lotion or cream remains unfoamed, but in a preferred embodiment of the invention, substantially all (e.g., 90% or more) of the gel, lotion, cream, etc. is foamed.

The present invention also includes a method of treating human skin, hair and/or mucous membranes comprising:

(a) providing a personal care composition in the form of a gel, lotion, cream or the like in a container, preferably under pressure, said gel, lotion or cream comprising: (i) one or more active ingredients; (ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components; and (iii) a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e));

(b) dispensing said gel, lotion or cream from said container onto the skin, hair and/or mucous membranes of the person being treated;

(c) foaming the gel, lotion or cream by evaporating the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) from the gel, lotion or cream; and

(d) spreading the gel, lotion, cream and/or foam onto and/or into the skin, hair and/or mucous membrane of the person being treated before, during and/or after the foaming step (c).

The present invention also includes a method of treating human skin, hair and/or mucous membranes comprising:

(a) providing a personal care composition in the form of a gel, lotion, cream, or the like comprising: (i) one or more active ingredients; (ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components; and (iii) a foam forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) and trans-1, 3,3, 3-tetrafluoropropene (1234ze (e));

(b) foaming the gel, lotion or cream by evaporating the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (E)) and/or the trans-1, 3,3, 3-tetrafluoropropene (1234ze (E)) from the gel, lotion or cream; and

(c) spreading the gel, lotion, cream and/or foam onto and/or into the skin, hair and/or mucous membrane of the person being treated before, during and/or after the foaming step (b).

The present invention also includes a method of treating human skin, hair and/or mucous membranes comprising:

(a) providing a personal care composition in the form of a gel, lotion, cream or the like in a container, preferably under pressure, said gel, lotion or cream comprising: (i) one or more active ingredients; (ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components; and (iii) a foam forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) and trans-1, 3,3, 3-tetrafluoropropene (1234ze (e));

(b) dispensing said gel, lotion or cream from said container onto the skin, hair and/or mucous membranes of the person being treated;

(c) foaming the gel, lotion or cream by evaporating the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) and/or trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)) from the gel, lotion or cream during and/or after the dispensing step; and

(d) during and/or after the foaming step (c), spreading the gel, lotion or cream on and/or into the skin, hair and/or mucous membranes of the person being treated.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 1% to about 50% by weight of a foam-forming component comprising, consisting essentially of, or consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 2.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 1 to about 50 weight percent of a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (E)) and trans-1, 3,3, 3-tetrafluoropropene (1234ze (E)), wherein the weight ratio of the 1234ze (E) to the 1233zd (E) is from about 90:10 to about 50:50, the weight percentages being based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 2.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 1% to about 10% by weight of a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 3.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 1% to about 10% by weight of a foam-forming component consisting essentially of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 4.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 1% to about 10% by weight of a foam-forming component consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 5.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 3 wt% to less than about 10 wt% of a foam-forming component comprising trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), the weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 6.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 3% to about 6% by weight of a foam-forming component consisting essentially of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 7.

The present invention includes a personal care formulation for treating human skin, hair and/or mucous membranes comprising a gel, lotion, cream or the like comprising:

(a) one or more active ingredients having a beneficial effect on human skin and/or hair and/or mucous membranes,

(b) optionally but preferably one or more auxiliary gel, lotion or cream forming components, and

(c) from about 3% to about 6% by weight of a foam-forming component consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (a), (b), and (c) in the formulation. For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 8.

The present invention also includes a personal care formulation in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 5% to about 50% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 50 to about 95 weight percent trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)) based on the total of components (1) and (2).

For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 9.

The present invention also includes a personal care formulation in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 15% to about 40% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 60 to about 85 weight percent trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)) based on the total of components (1) and (2).

For convenience, the personal care formulation according to this paragraph is sometimes referred to herein as personal care formulation 10.

The present invention includes a method of treating human skin, hair and/or mucous membranes comprising applying a personal care composition of the present invention (including each of the personal care formulations 1-10) to human skin, hair and/or mucous membranes.

The present invention includes a method of treating human skin, hair and/or mucous membranes comprising spreading a personal care composition of the present invention (including each of personal care formulations 1-10) on human skin, hair and/or mucous membranes.

The present invention includes a method of treating human skin, hair, and/or mucous membranes comprising delivering a personal care composition of the present invention (including each of personal care formulations 1-10) to the skin, hair, and/or mucous membranes of a human, and then foaming the delivered personal care composition.

The present invention includes a method of treating human skin, hair and/or mucous membranes comprising delivering a personal care composition of the present invention (including each of personal care formulations 1-10) to the skin, hair and/or mucous membranes of a human and then foaming the delivered personal care composition by vaporizing the foam-forming component.

The present invention includes a method of treating human skin, hair and/or mucous membranes, the method comprising: (a) providing a composition comprising one or more active ingredients and trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), wherein said one or more active ingredients are carried by and/or with said 1233zd (e);

(b) applying the personal care composition to and/or into the skin, hair and/or mucous membranes of the person being treated; and

(c) allowing said trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) to evaporate from said applied personal care composition, whereby at least a portion of said one or more active ingredients remain on and/or in the skin, hair, and/or mucous membranes of the person being treated during said evaporation, and whereby upon said evaporation, said person being treated experiences a cooling sensation.

As used herein, the term "vaporizing the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e))" and similar terms mean that at least a majority of the 1233zd is vaporized. Thus, the term includes within its meaning a step in which some portion of the 1233zd remains unevaporated, but in a preferred embodiment of the invention, substantially all (e.g., 90% or more) of the 1233zd is evaporated. It is also understood that the requirement that the one or more active ingredients remain on and/or in the skin, hair and/or mucous membranes of the person being treated includes "leave-on" compositions and methods as well as "rinse-off" compositions and methods. Thus, the present invention includes methods wherein the active ingredient is intended to remain on the skin, hair, and/or mucous membranes of the user without the user actively intending or attempting to remove the product. In such "leave-on" applications, it is preferred that substantially all of the 1233zd will be evaporated for a substantial period of time (e.g., 5 minutes or more) after application. On the other hand, in "rinse-off applications, it is expected that positive action will be taken to remove creams, lotions, gels, foams, etc. after application (such as by rinsing with water), and in such embodiments, it is expected that some, and possibly a substantial portion, of the 1233zd will be removed from the user prior to evaporation. Thus, "leave-on" and "rinse-off" applications are within the scope of the invention.

The present invention includes a method of treating human skin, hair and/or mucous membranes, the method comprising:

(a) providing a personal care composition comprising one or more active ingredients and from about 1 to about 50 weight% trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), wherein the one or more active ingredients are carried by and/or with the 1233zd (e), and wherein the weight percentages are based on the total amount of components in the personal care composition;

(b) applying the personal care composition to and/or into the skin, hair and/or mucous membranes of the person being treated; and

(c) allowing said trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) to evaporate from said applied personal care composition, whereby at least a portion of said one or more active ingredients remain on and/or in the skin, hair, and/or mucous membranes of the person being treated during said evaporation, and whereby upon said evaporation, said person being treated experiences a cooling sensation.

The present invention includes a method of treating human skin, hair and/or mucous membranes, the method comprising:

(a) providing a personal care composition comprising one or more active ingredients and from about 1 to about 50 weight% of a combination of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) and trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)), wherein: (i) the weight ratio of the 1234ze (E) to the 1233zd (E) is from about 90:10 to about 50: 50; (ii) the one or more active ingredients are carried by and/or with at least one of the 1233zd (E) and the 1234ze (E); and (iii) wherein the weight percentages are based on the total amount of components in the personal care composition;

(b) applying the personal care composition to and/or into the skin, hair and/or mucous membranes of the person being treated; and

(c) allowing said trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) to evaporate from said applied personal care composition, whereby at least a portion of said one or more active ingredients remain on and/or in the skin, hair, and/or mucous membranes of the person being treated during said evaporation, and whereby upon said evaporation, said person being treated experiences a cooling sensation.

The present invention includes articles for applying personal care formulations including gels, lotions, creams and the like for treating human skin, hair and/or mucous membranes, comprising:

(a) a closed container openable to dispense its contents;

(b) a personal care formulation contained within the container, the personal care formulation comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) from about 1% to about 50% by weight of a foam-forming component comprising, consisting essentially of, or consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), said weight percentages based on the total amount of components (i), (ii), and (iii) in the formulation; and

(c) optionally an external propellant for providing a force tending to expel the personal care composition from the container.

One skilled in the art will appreciate that the articles of the present invention comprise a closed container that can be opened to dispense the personal care compositions of the present invention. Thus, the invention includes containers in which the container is openable but not readily resealable (in the case of a can such as a pouch or the like which can be torn or torn to provide an opening for dispensing the personal care formulation), as well as containers which are resealable (in the case of a can or the like having a nozzle with a valve which can be opened to allow the personal care formulation to be dispensed and then resealed to retain the remainder of the formulation in the can for use at a later time). In either case, but primarily in the case of reclosable containers, it is contemplated that the foaming component of the present invention can also provide a force tending to expel the personal care formulation from the container. For example, in a preferred embodiment wherein the foaming component comprises both 1233zd and 1234ze, the 1234ze component in the personal care composition will typically exit the container with the formulation and will function not only to foam, but also to at least assist in the expulsion of the personal care formulation from the container. In such embodiments, the formulation preferably comprises 1233zd (e) and 1234ze (e) as components that are miscible with and/or dispersed in and/or emulsified with the formulation, and in such cases, the 1234ze (e) component will help to foam the formulation as it exits the container and provide propulsion. For the purposes of describing the present invention, 1234ze and other components that behave in the same or similar manner in such embodiments are encompassed by the term "lathering component" or the like, as it substantially contributes to the lathering of the personal care composition. It is contemplated that in other embodiments, 1234ze or other materials having a relatively high vapor pressure may be included in the container in such a way that they can act to help push the personal care composition out of the container but do not substantially contribute to foaming. Such embodiments may include, for example, providing a bag-on-valve type arrangement wherein the personal care composition of the present invention is contained within a bag within a container, while 1234ze is contained within the container but outside the bag, thus exerting an expulsion force on the personal care composition by applying pressure to the bag. (see, for example, US 20130184233, which is incorporated herein by reference). In this case, 1234ze outside the bag is referred to herein as the "external propellant". In other embodiments, the propellant is included in the canister, but remains largely separate from the personal care composition of the present invention, such as by being separated from the personal care composition, and in such embodiments, the propellant tends to remain in the canister as the personal care formulation is expelled. In such embodiments, the phase separated propellant will be considered an "external propellant" as it will not substantially contribute to the foaming of the personal care composition. All such embodiments are within the scope of the present invention.

Accordingly, the present invention includes articles for applying personal care formulations including gels, lotions, creams and the like for treating human skin, hair and/or mucous membranes, said articles comprising:

(a) a closed container openable to dispense its contents;

(b) a personal care formulation contained within the container, the personal care formulation being in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 5% to about 50% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 50 to about 95 weight percent trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)) based on the total of components (1) and (2); and

(c) optionally an external propellant for providing a force tending to expel the personal care composition from the container.

Accordingly, the present invention includes articles for applying personal care formulations including gels, lotions, creams and the like for treating human skin, hair and/or mucous membranes, said articles comprising:

(a) a closed container openable to dispense its contents;

(b) a personal care formulation contained within the container, the personal care formulation being in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 15% to about 40% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 60 to about 85 weight percent trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)) based on the total of components (1) and (2); and

(c) optionally an external propellant for providing a force tending to expel the personal care composition from the container.

The present invention also includes a method of treating the skin, hair and/or mucous membranes of a person with a personal care gel, lotion, cream, foam, or the like, comprising:

(a) providing a closed container capable of being opened to dispense its contents and containing therein a personal care formulation in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 5% to about 50% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 50% to about 95% by weight, based on the total amount of components (1) and (2), of a co-blowing agent other than said 1233zd (e), said co-blowing agent preferably comprising, consisting of, or consisting of trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)); and

(iv) optionally an external propellant for providing a force tending to expel the personal care composition from the container,

(b) dispensing the personal care formulation from the container by substantially simultaneously ejecting the personal care formulation from the container and initially foaming the personal care formulation, whereby the urging and initial foaming are provided by the co-foaming agent;

(c) applying the dispensed personal care formulation to the skin, hair and/or mucous membrane in the form of a foam; and

(d) after the coating step, providing a cooling sensation to the person being treated by evaporating at least a portion of the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) from the coated personal care composition.

The present invention also includes a method of treating the skin, hair and/or mucous membranes of a person with a personal care gel, lotion, cream, foam, or the like, comprising:

(a) providing a closed container capable of being opened to dispense its contents and containing therein a personal care formulation in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 15% to about 40% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 60% to about 85% by weight, based on the total amount of components (1) and (2), of a co-blowing agent other than said 1233zd (e), said co-blowing agent preferably comprising, consisting of, or consisting of trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)); and

(iv) optionally an external propellant for providing a force tending to expel the personal care composition from the container,

(b) dispensing the personal care formulation from the container by substantially simultaneously ejecting the personal care formulation from the container and initially foaming the personal care formulation, whereby the urging and initial foaming are provided by the co-foaming agent;

(c) applying the dispensed personal care formulation to the skin, hair and/or mucous membrane in the form of a foam; and

(d) after the coating step, providing a cooling sensation to the person being treated by evaporating at least a portion of the trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) from the coated personal care composition.

The present invention also includes a method of treating the skin, hair and/or mucous membranes of a person with a personal care gel, lotion, cream, foam, or the like, comprising:

(a) providing a closed container capable of being opened to dispense its contents and containing therein a personal care formulation in the form of an emulsion and/or dispersion comprising:

(i) one or more active ingredients having a beneficial effect on human skin and/or hair,

(ii) optionally but preferably one or more auxiliary gel, lotion or cream forming components,

(iii) (iii) a foam-forming component present in an amount of from about 30 to about 50 weight percent, based on the total weight of components (i), (ii), and (iii), said foam-forming component comprising, consisting essentially of, or consisting of:

(1) from about 15% to about 40% by weight, based on the total amount of components (1) and (2), of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and

(2) from about 60% to about 85% by weight, based on the total amount of components (1) and (2), of a co-blowing agent other than said 1233zd (e), said co-blowing agent preferably comprising, consisting of, or consisting of trans-1, 3,3, 3-tetrafluoropropene (1234ze (e)); and

(iv) optionally an external propellant for providing a force tending to expel the personal care composition from the container,

(b) dispensing the personal care formulation from the container by substantially simultaneously ejecting the personal care formulation from the container and initially foaming the personal care formulation, whereby the urging and initial foaming are provided by the co-foaming agent;

(c) applying the dispensed personal care formulation to the skin, hair and/or mucous membrane in the form of a foam; and

(d) providing a cooling sensation to the person being treated by evaporating at least a portion of said trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)) from said applied personal care composition after said applying step, wherein at least a portion of said one or more active ingredients remain on and/or in the skin, hair, and/or mucous membranes of the person being treated during said evaporating.

Drawings

The patent or application file contains at least one drawing executed in color. Copies of this patent or patent application publication with color drawing(s) will be provided by the office upon request and payment of the necessary fee.

Fig. 1A is a black and white photograph showing a front view obtained by the experiment described in example 3.

Fig. 1B is a black and white photograph showing a front view obtained by the experiment described in example 3.

Fig. 2 is a black and white photograph showing the results of the experiment described in example 4.

Fig. 3 is a black and white photograph showing the results of the experiment described in example 5.

Fig. 4 is a black and white photograph showing the results of the experiment described in example 6.

Fig. 5 is a color photograph showing the results of the experiment described in example 7.

Fig. 6 is a color photograph showing the results of the experiment described in example 8A.

Fig. 7 is a color photograph showing the results of the experiment described in example 11.

Fig. 8 is a color photograph showing the results of the experiment described in example 12.

Detailed Description

Preferred methods, articles and compositions of the present invention provide one or more, preferably several, unexpected properties as compared to existing personal care methods and personal care compositions. These performance advantages include:

improved spreadability

Improved wettability

Improved penetration of the active ingredient into the skin, hair and/or mucous membranes of the user

-a cooling sensation of the skin/mucous membranes felt after application or at least substantially immediately after application

-providing the user with an enhanced and long lasting cooling sensation, preferably without the use of a sensory sensation.

As used herein, the terms "personal care composition," "personal care formulation," and the like refer to compositions, formulations, and the like that are topically applied to a human.

The personal care compositions and formulations of the present invention may be in the form of, for example, lotions, creams, gels, and the like, and in each such form, the composition is preferably a post-foaming composition or formulation. Thus, it should be understood that while post-foaming formulations are preferred in many applications, non-post-foaming lotions, creams, gels, etc. are also within the broad scope of the present invention, including specific embodiments that provide a cooling sensation to the user. The compositions and formulations of the present invention may be in the form of a spray or atomised powder, mist or the like, which is typically a non-post-foaming composition, but which provides the advantageous cooling sensation of the present invention.

As used herein, the term "post-foaming" refers to gels, creams, lotions, and the like, which are not applied in substantially the form of a foam, but rather produce a foamed product as a result of the application of heat (which may be in the form of body heat) or other energy (such as kinetic energy associated with rubbing or spreading the formulation onto the skin and/or hair). For convenience, but not necessarily by way of limitation, compositions, formulations and methods relating to post-foaming are described below separately from non-post-foaming compositions, formulations and methods.

Post-foaming setCompounds, formulations and methods

The post-foaming aspect of the present invention may employ formulations and compositions in the form of lotions, creams, gels, and the like, with gels being preferred. In such embodiments, the formulations and compositions generally comprise: (a) one or more active ingredients, preferably comprising a detergent; (b) optionally but preferably, one or more auxiliary components which aid in the formation of a cream, lotion or gel and/or aid in the formation of a foam; (c) a blowing agent comprising, consisting essentially of, or consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and (d) optional additional components other than components (a), (b), and (c) that may be included in the composition.

For convenience, but not by way of limitation, components (a), (b), and (d) are sometimes referred to herein as a "formulation base" or "detergent base" (where the active component comprises a detergent) or "gel base" (where the formulation is in the form of a gel).

Active component

The active ingredients used in the compositions and methods of the present invention may have a variety of purposes and functions, and all such ingredients are within the scope of the present invention. Typically, such components will provide, or at least be expected to provide, some benefit to the user, preferably the user's skin, hair and/or mucous membranes. Thus, the active component may comprise a cosmetic agent (i.e. an agent that cosmetically treats, provides nutrition to, and/or conditions the skin, hair, or mucous membranes by topical application), a pharmaceutical agent (i.e. an agent that is capable of promoting or assisting recovery from injury or disease, preferably to the skin, hair, or mucous membranes), and a pharmaceutical agent (i.e. a pharmaceutical suitable for delivery by topical application, preferably including a pharmaceutical effective to treat the skin, hair, and mucous membranes). It will be appreciated by those skilled in the art that active ingredients may have more than one mode of operation and/or action and may therefore be suitably included in two or more classes of products for the purposes of the present invention.

Examples of active ingredients include, but are not limited to: colorants, depigmenting agents and appearance-altering agents (such as pigments, depigmenting agents, skin-lightening agents, reflecting agents, etc.); hair treatment agents (such as setting agents, disentangling agents, wet combing agents, hair loss preventive agents, hair growth promoters, hair growth inhibitors, hair dyes, hair conditioners, hair softeners, hair moisturizers, antidandruff agents, etc.); a film-forming polymer; a humectant; amino acids and derivatives thereof; an antimicrobial agent; an allergy inhibitor; anti-acne agents (such as salicylic acid, benzoyl peroxide, sulfur, adapalene and glycolic acid); anti-aging and anti-wrinkle agents (such as dimethylaminoethanol ("DMAE"), retinol, vitamin C, hydroxy acids, peptides, tea extract, grape seed extract, and niacinamide), preservatives; an analgesic; antitussive agents; antipruritic; a local anesthetic; an antihistamine; an anti-infective agent; an inflammation inhibitor; deodorants and antiperspirants (aluminum chlorohydrate and aluminum zirconium chlorohydrate); a medicament; skin emollients and skin moisturizers; a skin-tightening agent; an antifungal agent; shave preparations, agents, creams and gels; a fragrance; a cosmetic preparation; cosmetic agents (such as skin cleansers, skin conditioners, cosmetics, etc.); and sunscreen and sunblocks (such as benzophenone, polynitrone, paba butyl, cinnamide propyl trimethyl ammonium chloride, disodium distyryl dibenzosulfonate, paba, potassium methoxycinnamate, butyl methoxydibenzoylmethane, octyl methoxycinnamate, oxybenzone, octocrylene, octyl salicylate, phenylbenzimidazole sulfonic acid, ethyl hydroxypropylaminobenzoate, menthyl anthranilate, aminobenzoic acid, cinoxate, diethanolamine methoxycinnamate, glyceryl aminobenzoate, titanium dioxide, zinc oxide, oxybenzone, palisade 0, and red petrolatum); insect repellents, skin protectants (such as atmeal, beta glucan, feverfew, soy and its derivatives, soda bicarbonate, colloidal oatmeal, surfactant-based colloidal oatmeal cleansers, caraway, evening primrose, verbena, etc.), vitamins (such as vitamin B complex; including thiamine, niacin, biotin, pantothenic acid, choline, riboflavin, vitamin B6, vitamin B12, pyridoxine, inositol, carnitine; vitamin A, C, D, E, K and their derivatives, such as vitamin a palmitate and provitamins, for example (i.e. panthenol (provitamin B5) and panthenyl triacetate).

The amount of active ingredient used in the present invention may vary widely depending on the particular application, and all such amounts may be determined by one skilled in the art in light of the teachings contained herein, and are within the broad scope of the present invention. For example, the amount of active ingredient may vary depending on the ability of the ingredient to penetrate through, onto or into the pores of the skin, hair or mucosa in view of the enhancement provided by the present invention. Other factors that may affect the relative amounts of the active ingredients include the particular active ingredients involved, the particular benefit desired, the sensitivity of the user to the active ingredients, the health condition of the user, age, skin, hair, and/or mucosal condition, and the like. In general, the benefit agent is preferably used in a "safe and effective amount" that is high enough to deliver the desired skin, hair or mucosal benefit or modify certain conditions to be treated, and avoid undesirable harmful serious side effects. In preferred embodiments, the active components are together present in the personal care composition or personal care formulation system in an amount of from about 0.01 wt% to about 50 wt%, from about 0.01 wt% to about 20 wt%, from about 0.01 wt% to about 10 wt%, from about 0.01 wt% to about 5 wt%, or from about 0.01 wt% to about 1.0 wt%, based on the total weight of the composition/formulation.

Auxiliary gel, lotion or cream forming components

The types of auxiliary components that may be used in the formulations of the present invention may vary widely depending on the particular form of formulation (e.g., gel, cream, or lotion) and the particular attributes of the formulation desired, and any and all such components are included within the scope of the present invention.

For example, with respect to gels, in preferred embodiments, the gel-forming component preferably comprises an aqueous soap in a major proportion based on the total weight of the formulation. The soap in the aqueous soap component can be, for example, soap or a surfactant, sometimes referred to as a humectant, which is generally characterized as anionic or nonionic.

Soaps (water soluble salts, preferably amine or alkaline salts, of higher fatty acids) suitable for use in producing the post-foaming gel are generally known in the art and all such soaps are within the scope of the present invention. Generally, such components may preferably be alkali, ammonium or soluble amine salts of fatty acids, such as stearic acid, palmitic acid, myristic acid and the like. Soaps may also be prepared by neutralizing or saponifying animal fats, such as tallow or vegetable fats, as is known in the art. The selection of suitable soap components is considered to be within the purview of one skilled in the art in light of the teachings herein.

Anionic or nonionic surfactants that may be used in place of or in combination with soap should be anionic or nonionic surfactants that are significantly soluble in water, and as examples of such agents, triethanolamine lauryl sulfate, sodium dodecylbenzenesulfonate, water-soluble polyoxyethylene ethers of alkyl-substituted phenols, and water-soluble polyoxyethylene cetyl ether may be mentioned. The selection of suitable wetting agents is considered to be within the purview of one skilled in the art in view of the teachings herein.

It has been recognized that one difficulty associated with forming gels for post-foaming applications is the difficulty of forming gels that, in their unfoamed state, do not readily spread in a uniform and fluid manner on the skin or hair. See, for example, US 5,334,325, which describes the use of specific alkoxylated alkyl phosphate ester surfactants, the contents of which are incorporated herein by reference.

Other adjunct ingredients for post-foaming applications that may be included in the gels, creams and lotions of the present invention include polymers for gel thickening and lubrication, cosmetic esters for skin moisturizing, humectants for moisturizing, fragrances, dyes and preservatives.

The amounts of the adjunct components used in the present invention can vary widely depending on the particular application, and all such amounts can be determined by one skilled in the art in light of the teachings contained herein and are within the broad scope of the present invention. In preferred embodiments, the adjunct components are together present in the personal care composition or personal care formulation system in an amount of from about 40 wt.% to about 90 wt.%, from about 50 wt.% to about 80 wt.%, or from about 50 wt.% to about 70 wt.%, based on the total weight of the composition/formulation.

Foaming agent

As noted above, the blowing agent used in the present formulations and methods comprises 1-chloro-3, 3, 3-trifluoropropene (1233 zd). While it is contemplated that the 1233zd employed in connection with the present invention can be in the trans or cis isomer form, and any and all combinations thereof, in preferred embodiments, the 1233zd preferably comprises at least about 80%, preferably at least about 90%, preferably at least about 95%, or preferably at least about 97% trans 1233 zd. In a preferred embodiment, the 1233zd present in the formulation consists essentially of or consists of trans 1233 zd.

It is contemplated that the blowing agent may comprise relative amounts of 1233zd, preferably trans 1233zd, which may vary widely depending on the particular performance parameters desired for any particular application. In a preferred embodiment, the blowing agent comprises at least about 5 wt.% trans 1233zd, and preferably from about 5 wt.% to about 100 wt.% trans 1233 zd. The present invention also includes embodiments wherein the blowing agent comprises a relative amount of 1233zd, and preferably trans 1233zd, from about 5 wt% to about 60 wt% trans 1233 zd. The present invention also includes embodiments wherein the blowing agent comprises a relative amount of 1233zd, and preferably trans 1233zd, at least about 10 wt% trans 1233zd, or preferably from about 10 wt% to about 100 wt% trans 1233 zd. The present invention also includes embodiments wherein the blowing agent comprises from about 10 wt% to about 60 wt% trans 1233 zd.

Non-post-foaming compositions, formulations and methods

As mentioned above, the present invention also includes creams, lotions, gels, foams, mists, powders, sprays, and the like, which do not exhibit post-foaming action. For example, the advantageous cooling effects described herein may even be provided by creams, lotions, gels, foams, mists, powders, sprays, and the like that are designed not to exhibit a post-foaming effect, but wherein the 1233zd of the present invention evaporates after application of the cream, lotion, gel, foam, mist, powder, spray, and the like to the skin, hair, and/or mucous membranes of the user and thus provides the advantageous cooling effects described herein. As another example, the advantageous ability of the formulations of the present invention, as comprised in a portion of the 1233zd of the present invention, provides the advantageous ability of the active ingredient to penetrate and/or be delivered directly into the skin/mucosal pores of the user and/or the hair follicle of the user, even in embodiments where a post-foaming effect is not achieved or desired.

Thus, non-post-foaming embodiments of the present invention may also use formulations and compositions in the form of creams, lotions, gels, foams, mists, powders, sprays, and the like, wherein the formulations and compositions typically comprise: (a) one or more active ingredients, preferably comprising a detergent; (b) optionally but preferably, one or more auxiliary components which aid in the formation of creams, lotions, gels, foams, mists, powders, sprays and the like; (c) a blowing agent comprising, consisting essentially of, or consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)); and (d) optional additional components other than components (a), (b), and (c) that may be included in the composition. In such non-post foaming applications, the types and amounts of components (a), (b), and (c) can vary widely, and include the types and amounts of such components as described herein in connection with post foaming applications. In non-post-foaming embodiments, for convenience, but not by way of limitation, components (a), (b), and (d) are also sometimes referred to herein as "formulation bases" or "detergent bases" (where the active component comprises a detergent), and the like.

Preferred embodiments

A preferred embodiment of the present invention comprises from about 80 to about 99 wt% of a detergent base and from about 1 to about 20 wt% of a blowing agent comprising, consisting essentially of, or consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), wherein the percentages are based on weight.

Preferred embodiments of the present invention comprise from about 80 to about 99 wt% of the detergent matrix and from about 1 to about 20 wt% of the foaming agent, wherein the foaming agent comprises at least about 50 wt% 1233zd (e), at least about 75 wt% 1233zd (e), at least about 80 wt% 1233zd (e), at least about 90 wt% 1233zd (e), or at least about 100 wt% based on all foaming agents in the composition.

A preferred embodiment of the present invention comprises from about 80 to about 99 wt% of a detergent base and from about 1 to about 10 wt% of a blowing agent comprising, consisting essentially of, or consisting of trans-1-chloro-3, 3, 3-trifluoropropene (1233zd (e)), wherein the percentages are based on weight.

Preferred embodiments of the present invention comprise from about 50 wt% to about 99 wt% of the detergent matrix and from about 1 wt% to about 50 wt% of the foaming agent, wherein the foaming agent comprises at least about 5 wt% 1233zd (e), at least about 10 wt% 1233zd (e), from about 5 wt% to about 50 wt% 1233zd (e), or at least about 10 wt% to about 40 wt% 1233zd (e), based on all foaming agents in the composition.

A preferred embodiment of the present invention comprises from about 90 wt% to about 99 wt% of the detergent matrix and from greater than 1 wt% to less than about 10 wt% of a foaming agent, wherein the foaming agent comprises at least about 50 wt% 1233zd (e) based on all foaming agents in the composition.

A preferred embodiment of the present invention comprises from about 90 wt% to about 99 wt% of the detergent matrix and from greater than 1 wt% to less than about 10 wt% of a foaming agent, wherein the foaming agent comprises at least about 75 wt% 1233zd (e) based on all foaming agents in the composition.

A preferred embodiment of the present invention comprises from about 90 wt% to about 99 wt% of the detergent matrix and from greater than 1 wt% to less than about 10 wt% of a foaming agent, wherein the foaming agent comprises at least about 80 wt% 1233zd (e) based on all foaming agents in the composition.

A preferred embodiment of the present invention comprises from about 90 wt% to about 99 wt% of the detergent matrix and from greater than 1 wt% to less than about 10 wt% of a foaming agent, wherein the foaming agent comprises at least about 90 wt% 1233zd (e) based on all foaming agents in the composition.

The personal care compositions of the present invention may be in the form of and/or for use in a variety of personal care products/applications, including: shampoos (including baby shampoo, conditioning shampoo, moisturizing shampoo, and the like); skin and body cleansers (including shower gels, bath lotions, facial cleansers, intimate cleansers, moisturizing baths, antibacterial baths, body washes, hand soaps, facial scrubs, foot scrubs, etc.); hair care compositions (including hair dyes, hair conditioners, hair creams and hair styling preparations); skin care compositions (including skin lotions, balms and creams, skin whiteners, self-tanning lotions, sun screens, carrier lotions, moisturizers, vitamin C creams, antibacterial lotions, masks, body masks, cosmetic foundations, sun screens, antiperspirants, etc.).