阅读说明：本技术 一种小型动物实验采血装置及其使用方法 (Small animal experiment blood sampling device and using method thereof ) 是由 王宜春 于 2020-05-14 设计创作，主要内容包括：本发明涉及实验采血工具领域,具体为一种小型动物实验采血装置及其使用方法,包括采血台,采血台上固定有两条相互平行的滑轨,每一条所述滑轨上均滑动连接有一个滑架,滑架上固定有立杆,两个所述立杆之间固定有横撑板,横撑板的中部设置有采血机构,采血机构上设置有采血器,立杆上设置有定位机构,且定位机构可与采血机构抵扣接触,并对采血机构进行固定锁紧,定位机构可与滑轨抵扣接触,横撑板上设置有消毒机构,且消毒机构与定位机构传动连接,消毒机构用来对采血器进行消毒。该种小型动物实验采血装置及其使用方法,确保采血过程中安全可靠,避免对小白鼠的心脏在采血时产生损坏,提高采血安全性,防止病菌感染,省时省力。(The invention relates to the field of experimental blood sampling tools, in particular to a small animal experimental blood sampling device and a using method thereof. The small animal experiment blood sampling device and the use method thereof ensure safety and reliability in the blood sampling process, avoid damage to the heart of a white mouse during blood sampling, improve the blood sampling safety, prevent germ infection and save time and labor.)

1. The utility model provides a small-size animal experiment blood sampling device, includes blood sampling platform (1), its characterized in that: be fixed with two slide rail (2) that are parallel to each other on blood sampling platform (1), each equal sliding connection has a balladeur train (3) on slide rail (2), be fixed with pole setting (4) on balladeur train (3), two be fixed with cross bracing board (14) between pole setting (4), the middle part of cross bracing board (14) is provided with blood sampling mechanism, be provided with the hemostix in the blood sampling mechanism, be provided with positioning mechanism on pole setting (4), and positioning mechanism can support the knot contact with blood sampling mechanism to fix the locking to blood sampling mechanism, positioning mechanism can support the knot contact with slide rail (2), be provided with disinfection mechanism (34) on cross bracing board (14), and disinfection mechanism (34) are connected with the positioning mechanism transmission, disinfection mechanism (34) are used for disinfecting to the hemostix.

2. The small animal experiment blood sampling device of claim 1, wherein: the utility model discloses a blood sampling device, including cross bracing piece (14), pole setting (4), blood sampling mechanism, ball hinge seat (15), positioning mechanism, ball (16) are connected with ball hinge seat (15), the positioning mechanism can support the knot contact with ball (16) and contact, cross bracing piece (14) and pole setting (4) are perpendicular, pole setting (4) vertical direction sets up, and cross bracing piece (14) are perpendicular with slide rail (2) antarafacial, blood sampling mechanism is including fixing ball hinge seat (15) on cross bracing piece (14), and the upper and lower both ends of ball hinge seat (15) are opening column structure, ball hinge seat (15) inside is provided with ball (16), ball (16) are connected with.

3. The small animal experiment blood sampling device of claim 2, wherein: the upper end of ball (16) is fixed with sliding sleeve (19), the one end that ball (16) was kept away from in sliding sleeve (19) is fixed with backup pad (20) and backup pad two (23), and backup pad one (20) and backup pad two (23) are located the both sides of sliding sleeve (19) respectively, sliding sleeve (19) inside sliding connection has slide bar (18), the upper end of slide bar (18) is fixed with clamp two (27) and dead lever (22), and clamp two (27) and dead lever (22) are located the both sides of slide bar (18) upper end, dead lever (22) are located the top of backup pad one (20), be fixed with cylinder (21) on backup pad one (20), the piston rod end fixed connection dead lever (22) of cylinder (21), clamp two (27) are located the top of backup pad two (23), be fixed with branch (24) on backup pad two (23), and the supporting rod (24) is parallel to the sliding rod (18), and a first clamp (25) is fixed at the upper end of the supporting rod (24).

4. The small animal experiment blood sampling device of claim 3, wherein: the ball is characterized in that a slide way (17) is arranged on the ball (16), the central axis of the slide way (17) coincides with the central axis of the sliding sleeve (19), the central axis of the slide way (17) passes through the center of the ball (16), the upper port of the slide way (17) is communicated with the lower port of the sliding sleeve (19), and a clamping needle cylinder (35) is fixed at the lower end of the sliding rod (18).

5. The small animal experiment blood sampling device of claim 4, wherein: the hemostix comprises a vacuum blood collection tube (26), a puncture needle (33), a hose and a blood discharge needle (28), wherein the vacuum blood collection tube (26) is buckled on a first clamp (25), the first clamp (25) is in an open ring shape, the first clamp (25) is made of a metal elastic sheet, the middle part of the first clamp (25) is fixed at the upper end of a support rod (24), the blood discharge needle (28) is buckled on a second clamp (27), an open notch is formed in the second clamp (27), the second clamp (27) is made of hard rubber, the upper end of the puncture needle (33) is in a ball head shape, an annular groove (43) is formed in the ball head part of the puncture needle (33), the ball head end of the puncture needle (33) is inserted into the needle clamping tube (35), a rubber ring (44) is fixed in the middle part of the inner wall of the needle clamping tube (35), and the rubber ring (44) can be buckled in the annular groove (43), the side wall of the upper end part of the puncture needle (33) is connected with the blood discharging needle (28) through a hose.

6. The small animal experiment blood sampling device of claim 5, wherein: disinfection mechanism (34) are including fixing pump barrel (37) on horizontal fagging (14), and pump barrel (37) are located the left side of ball free bearing (15), the inside sliding connection of pump barrel (37) has piston plate (38), the left side of piston plate (38) is fixed with ejector pin (39), the left end and the positioning mechanism transmission of ejector pin (39) are connected, the right-hand member of pump barrel (37) is fixed with check valve (41) and check valve two (42), the upper end of pole setting (4) of horizontal fagging (14) left end is fixed with disinfectant tank (12), the pipeline connection disinfectant tank (12) are passed through in check valve (41), the directional pump barrel (13) of the direction of conducting of check valve (41).

7. The small animal experiment blood sampling device of claim 6, wherein: the disinfection mechanism (34) further comprises a support (31) fixed at the lower end of the ball (16), a disinfection cylinder (32) is fixed at the lower end of the support (31), a flange cover (36) is connected to the lower end of the disinfection cylinder (32), the disinfection cylinder (32) is connected with a second one-way valve (42) through a pipeline, the conduction direction of the second one-way valve (42) points to the disinfection cylinder (32), a disinfection cotton sleeve (45) is sleeved inside the disinfection cylinder (32), the puncture needle (33) can sequentially penetrate through the upper end face of the disinfection cylinder (32), the centers of the disinfection cotton sleeve (45) and the flange cover (36), and the puncture needle (33) can slide on the upper end face of the disinfection cylinder (32), the disinfection cotton sleeve (45) and the flange cover (36).

8. The small animal experiment blood sampling device of claim 6, wherein: the positioning mechanism comprises a screw rod (13), the screw rod (13) is parallel to the cross support plate (14), the screw rod (13) is positioned above the cross supporting plate (14), the screw rod (13) is connected in a threaded hole (29) which is arranged at the upper end of the upright rod (4) in a threaded way, one end of the screw rod (13) pointing to the spherical hinged support (15) can be connected in a through hole (30) arranged on the spherical hinged support (15) in a sliding way, one end of the screw rod (13) pointing to the spherical hinge seat (15) can be in abutting contact with the ball (16), a second sleeve (40) is sleeved on the screw rod (13) positioned on the left side of the spherical hinge seat (15), the second sleeve (40) can rotate on the screw (13), convex rings II for limiting the second sleeve (40) are arranged on two sides of the second sleeve (40), the second convex ring is fixed on the screw rod (13), and the second sleeve (40) is fixedly connected with the left end of the ejector rod (39); the positioning mechanism also comprises a guide sleeve (8) fixed on the upright stanchion (4), a pressure lever (7) is connected inside the guide sleeve (8) in a sliding way, the pressing rod (7) is parallel to the upright rod (4), the lower end of the pressing rod (7) passes through the corresponding sliding frame (3) and is positioned in a groove (5) arranged in the sliding frame (3), the compression bar (7) can slide up and down on the sliding frame (3), the toothed plate (6) is connected in the groove (5) in a sliding way, the lower surface of the toothed plate (6) can be in abutting-buckling contact with the upper surface of the sliding rail (2), the upper surface of the sliding rail (2) is provided with teeth, the cross section of the sliding rail (2) is T-shaped, the upper end of the pressure lever (7) is hinged with the first sleeve (11) through a connecting rod (9), the first sleeve (11) is sleeved on the screw rod (13), and the first sleeve (11) can rotate on the screw rod (13).

9. The small animal experiment blood sampling device of claim 8, wherein: the two sides of the first sleeve (11) are provided with a first convex ring for limiting the first sleeve (11), and the first convex ring is fixed on the screw rod (13).

10. The use of a small animal experimental blood collection device according to any one of claims 1 to 9, wherein: the method comprises the following steps:

the method comprises the following steps: positioning blood collection through a positioning mechanism, and adjusting the blood collection angle of the blood collection mechanism;

step two: the positioning mechanism drives the disinfection mechanism (34) to disinfect the blood sampling mechanism;

step three: blood is collected by a blood collecting mechanism.

Technical Field

The invention relates to the field of experimental blood sampling tools, in particular to a small animal experimental blood sampling device and a using method thereof.

Background

Mice are varieties of wild traggine rats, belonging to the kingdom animalia, phylum vertebrata, class mammalia, order rodentia, species of rats. The most widely bred in China is the variety introduced from some institute in India to Yunnan Kunming breeding in 1946, and most of the variety is used for medical research.

The laboratory mouse, the white mouse and the white mouse refer to a white fur rat or a white fur mouse which is generally used as a laboratory animal in teaching and research of physiological, medical, pharmaceutical and other subjects. The method is widely applied to experiments and tests on safety, toxicity, efficacy and the like of foods, cosmetics, medicines, biological products, industrial products, medicine, life sciences and the like.

The blood sampling operation on the experimental white mouse is one operation which is often carried out in the experiment, and the blood sampling operation on the experimental white mouse is divided into three blood sampling modes, namely: tail point blood sampling, orbit blood sampling and heart blood sampling, wherein need anaesthetize the mice in the heart blood sampling operation usually, and bind it at the blood sampling bench, then handheld hemostix takes a blood sample, at the blood sampling in-process, because the skilled level and hand shake for the reasons such as people can lead to the blood sampling needle to prick the heart position inaccurate often, and at the blood sampling in-process, thereby the blood sampling needle can not remain stable moreover and lead to the blood sampling to cause serious damage to the heart of mice, influence the experimental result.

In view of this, we propose a small animal experiment blood sampling device and its method of use.

Disclosure of Invention

The invention aims to provide a small animal experiment blood sampling device and a using method thereof, which aim to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

first aspect, this application provides a toy tests blood sampling device, including the blood sampling platform, the bench of taking a blood sample is fixed with two slide rails that are parallel to each other, each equal sliding connection has a balladeur train on the slide rail, is fixed with the pole setting on the balladeur train, two be fixed with the cross bracing board between the pole setting, the middle part of cross bracing board is provided with blood sampling mechanism, is provided with the hemostix in the blood sampling mechanism, is provided with positioning mechanism in the pole setting, and positioning mechanism can support the knot contact with blood sampling mechanism to fix locking to blood sampling mechanism, positioning mechanism can support the knot contact with the slide rail, is provided with disinfection mechanism on the cross bracing board, and disinfection mechanism is connected with the positioning mechanism transmission, and disinfection mechanism is used for disinfecting the hemostix.

Preferably, the cross supporting plate is perpendicular to and fixedly connected with the vertical rod, the vertical direction of the vertical rod is arranged, the cross supporting plate is perpendicular to the different surface of the slide rail, the blood sampling mechanism comprises a ball hinge seat fixed on the cross supporting plate, the upper end and the lower end of the ball hinge seat are both of an open structure, balls are arranged inside the ball hinge seat and are connected with the ball hinge seat in a ball hinge connection mode, and the positioning mechanism can be in buckling contact with the balls.

Preferably, the upper end of ball is fixed with the sliding sleeve, the one end that the ball was kept away from to the sliding sleeve is fixed with backup pad one and backup pad two, and backup pad one and backup pad two are located the both sides of sliding sleeve respectively, the inside sliding connection of sliding sleeve has the slide bar, the upper end of slide bar is fixed with clamp two and dead lever, and clamp two and dead lever are located the both sides of slide bar upper end, the dead lever is located the top of backup pad one, be fixed with the cylinder in the backup pad one, the piston rod end fixed connection dead lever of cylinder, clamp two is located the top of backup pad two, be fixed with branch in the backup pad two, and branch is parallel with the slide bar.

Preferably, the ball is provided with a slide way, the central axis of the slide way coincides with the central axis of the sliding sleeve, the central axis of the slide way passes through the ball center of the ball, the upper port of the slide way is communicated with the lower port of the sliding sleeve, and the lower end of the sliding rod is fixed with a clamping needle cylinder.

Preferably, the hemostix includes the vacuum test tube, the pjncture needle, hose and blood discharge needle, the vacuum test tube buckle is on clamp one, clamp one is open-ended cyclic annular, and clamp one is made by metal shrapnel, the upper end at branch is fixed at the middle part of clamp one, blood discharge needle buckle is on clamp two, open-ended notch has been seted up on clamp two, and clamp two is made by carbide rubber, the upper end of pjncture needle is the bulb form, and the bulb portion of pjncture needle has seted up the annular, the bulb end of pjncture needle is pegged graft in the card cylinder, and the inner wall middle part of card cylinder is fixed with the rubber circle, and but the rubber circle lock joint is in the annular, the upper end lateral wall of pjncture needle is connected with blood.

Preferably, disinfection mechanism is including fixing the pump barrel on the spreader, and the pump barrel is located the left side of ball hinged-seat, and the inside sliding connection of pump barrel has the piston board, and the left side of piston board is fixed with the ejector pin, and the left end and the positioning mechanism transmission of ejector pin are connected, and the right-hand member of pump barrel is fixed with check valve one and check valve two, and the upper end of the pole setting of spreader plate left end is fixed with the disinfectant box, and check valve one passes through the tube coupling disinfectant box, the directional pump barrel of the direction that switches on of check valve one.

Preferably, disinfection mechanism is still including fixing the support at the lower extreme of ball, the lower extreme of support is fixed with a disinfection section of thick bamboo, the lower extreme threaded connection of a disinfection section of thick bamboo has the blind flange, a disinfection section of thick bamboo passes through the pipeline and is connected with check valve two phase, the directional disinfection section of thick bamboo of the direction that switches on of check valve two, the inside disinfection cotton cover that has cup jointed of a disinfection section of thick bamboo, the pjncture needle can pass the up end of a disinfection section of thick bamboo in proper order, the center of disinfection cotton cover and blind flange, and the pjncture needle can slide on the up end of a disinfection section of.

Preferably, the positioning mechanism comprises a screw rod, the screw rod is parallel to the cross supporting plate, the screw rod is located above the cross supporting plate, the screw rod is in threaded hole formed in the upper end of the vertical rod in threaded connection, one end of the screw rod, pointing to the spherical hinge seat, can be slidably connected in a through hole formed in the spherical hinge seat, one end of the screw rod, pointing to the spherical hinge seat, can be in buckling contact with a spherical ball, a second sleeve is sleeved on the screw rod located on the left side of the spherical hinge seat, the second sleeve can rotate on the screw rod, two sides of the second sleeve are provided with a second convex ring limiting the second sleeve, the second convex ring is fixed on the screw rod, and the second sleeve is fixedly.

Preferably, positioning mechanism is still including fixing the uide bushing in the pole setting, the inside sliding connection of uide bushing has the depression bar, the depression bar is parallel to each other with the pole setting, the lower extreme of depression bar passes the balladeur train that corresponds and is located and offers the inside recess of balladeur train, and the depression bar can slide from top to bottom on the balladeur train, the inside sliding connection of recess has the pinion rack, the lower surface of pinion rack can support the knot with the upper surface of slide rail and contact, the tooth has been seted up to the upper surface of slide rail, and the cross section of slide rail is the T type, the upper end of depression bar is articulated through connecting rod and sleeve pipe one, the sleeve pipe cup joints on the screw rod, and sleeve pipe one can rotate on the screw rod, the both sides of sleeve.

In a second aspect, the present application also provides a method for using a small animal experimental blood sampling device, comprising the following steps:

the method comprises the following steps: positioning blood collection through a positioning mechanism, and adjusting the blood collection angle of the blood collection mechanism;

step two: the positioning mechanism drives the disinfection mechanism to disinfect the blood sampling mechanism;

step three: blood is collected by a blood collecting mechanism.

Compared with the prior art, the invention has the beneficial effects that:

according to the invention, the positioning mechanism keeps the blood sampling mechanism immovable after the position and the needle insertion angle of the blood sampling mechanism are adjusted, so that the blood sampling mechanism is ensured to be kept stable in the blood sampling process, the normal running of blood sampling is ensured, the damage to the heart of a white rat is avoided during blood sampling, the disinfection mechanism is used for carrying out disinfection treatment on the blood sampling mechanism, the blood sampling safety is improved, the germ infection is prevented, the blood sampling operation on the white rat is realized through the blood sampling mechanism, the whole process is simple and convenient to operate, safe and reliable, the blood sampling success rate is improved, and the time and labor are saved.

Drawings

FIG. 1 is a first schematic view of the cross-sectional structure of the final assembly of the present invention;

FIG. 2 is a schematic view of the cross-sectional structure of the final assembly of the present invention;

FIG. 3 is an enlarged schematic view of the structure at A in FIG. 1;

FIG. 4 is an enlarged view of the structure at B in FIG. 1;

FIG. 5 is a schematic view of the blood collection table according to the present invention;

FIG. 6 is a top view of a second clamp of the present invention;

fig. 7 is a top view of a clip according to the present invention.

In the figure: 1. a blood collection table; 2. a slide rail; 3. a carriage; 4. erecting a rod; 5. a groove; 6. a toothed plate; 7. a pressure lever; 8. a guide sleeve; 9. a connecting rod; 10. a turntable; 11. a first sleeve; 12. a disinfectant tank; 13. a screw; 14. a cross bracing plate; 15. a spherical hinge seat; 16. a ball; 17. a slideway; 18. a slide bar; 19. a sliding sleeve; 20. a first support plate; 21. a cylinder; 22. fixing the rod; 23. a second support plate; 24. a strut; 25. a first hoop is clamped; 26. a vacuum blood collection tube; 27. a second hoop; 28. blood drainage needle; 29. a threaded hole; 30. a through hole; 31. a support; 32. a sterilizing cylinder; 33. puncturing needle; 34. a sterilizing mechanism; 35. clamping the needle cylinder; 36. a flange cover; 37. a pump barrel; 38. a piston plate; 39. a top rod; 40. a second sleeve; 41. a one-way valve I; 42. a second one-way valve; 43. a ring groove; 44. a rubber ring; 45. a sterilized cotton sleeve.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

Referring to fig. 1 to 7, the present invention provides a technical solution:

the utility model provides a toy experiment blood sampling device, includes blood sampling platform 1, is fixed with two slide rails 2 that are parallel to each other on the blood sampling platform 1, each equal sliding connection has a balladeur train 3 on the slide rail 2, is fixed with pole setting 4 on the balladeur train 3, two be fixed with cross bracing board 14 between the pole setting 4, cross bracing board 14's middle part is provided with blood sampling mechanism, is provided with the hemostix in the blood sampling mechanism, is provided with positioning mechanism in the pole setting 4, and positioning mechanism can support with blood sampling mechanism and detain the contact to fixing locking blood sampling mechanism, positioning mechanism can support with slide rail 2 and detain the contact, be provided with disinfection mechanism 34 on the cross bracing board 14, and disinfection mechanism 34 is connected with the positioning mechanism transmission, disinfection mechanism 34 is used for disinfecting the hemostix.

In this embodiment, as shown in fig. 1 and fig. 2, the cross plate 14 is perpendicular to and fixedly connected with the vertical rod 4, the vertical rod 4 is disposed in the vertical direction, the cross plate 14 is perpendicular to the different surface of the slide rail 2, the blood sampling mechanism includes a ball hinge seat 15 fixed on the cross plate 14, the upper end and the lower end of the ball hinge seat 15 are both open structures, a ball 16 is disposed inside the ball hinge seat 15, the ball 16 is connected with the ball hinge seat 15 in a ball hinge connection manner, and the positioning mechanism can be in abutting contact with the ball 16.

In this embodiment, as shown in fig. 1 and fig. 2, a sliding sleeve 19 is fixed at the upper end of the ball 16, one end of the sliding sleeve 19, which is away from the ball 16, is fixed with a first support plate 20 and a second support plate 23, the first support plate 20 and the second support plate 23 are respectively located at two sides of the sliding sleeve 19, a sliding rod 18 is slidably connected inside the sliding sleeve 19, a second clamp 27 and a fixed rod 22 are fixed at the upper end of the sliding rod 18, the second clamp 27 and the fixed rod 22 are located at two sides of the upper end of the sliding rod 18, the fixed rod 22 is located above the first support plate 20, a cylinder 21 is fixed on the first support plate 20, the fixed rod 22 is fixedly connected to a piston rod end of the cylinder 21, the second clamp 27 is located above the second support plate 23, a supporting rod 24 is fixed.

In this embodiment, as shown in fig. 1 and 2, a slide way 17 is disposed on the ball 16, a central axis of the slide way 17 coincides with a central axis of the slide sleeve 19, the central axis of the slide way 17 passes through a center of the ball 16, an upper port of the slide way 17 is communicated with a lower port of the slide sleeve 19, and a needle clamping cylinder 35 is fixed at a lower end of the slide rod 18.

In this embodiment, as shown in fig. 1 and fig. 2, the blood collection device includes a vacuum blood collection tube 26, a puncture needle 33, a flexible tube and a blood discharge needle 28, the vacuum blood collection tube 26 is fastened to a first clamp 25, as shown in fig. 7, the first clamp 25 is in an open ring shape, the first clamp 25 is made of a metal elastic sheet, the middle portion of the first clamp 25 is fixed to the upper end of the support rod 24, the blood discharge needle 28 is fastened to a second clamp 27, as shown in fig. 6, the second clamp 27 is provided with an open notch, the second clamp 27 is made of hard rubber, the upper end of the puncture needle 33 is in a ball head shape, the ball head portion of the puncture needle 33 is provided with a ring groove 43, the ball head end of the puncture needle 33 is inserted into the needle cylinder 35, the middle portion of the inner wall of the needle cylinder 35 is fixed with a rubber ring 44, the rubber ring 44 can be fastened in the ring groove 43.

In this embodiment, as shown in fig. 3 and 4, the disinfecting mechanism 34 includes a pump barrel 37 fixed on the cross plate 14, the pump barrel 37 is located on the left side of the spherical hinge seat 15, a piston plate 38 is slidably connected inside the pump barrel 37, a push rod 39 is fixed on the left side of the piston plate 38, the left end of the push rod 39 is in transmission connection with the positioning mechanism, a first check valve 41 and a second check valve 42 are fixed on the right end of the pump barrel 37, a disinfecting liquid tank 12 is fixed on the upper end of the upright rod 4 at the left end of the cross plate 14, the first check valve 41 is connected with the disinfecting liquid tank 12 through a pipeline, and the conducting direction of the first check valve 41 points to the pump barrel 37.

In this embodiment, as shown in fig. 3 and 4, the disinfecting mechanism 34 further includes a support 31 fixed at the lower end of the ball 16, a disinfecting cylinder 32 is fixed at the lower end of the support 31, a flange cover 36 is connected to the lower end of the disinfecting cylinder 32 through a thread, the disinfecting cylinder 32 is connected to a second one-way valve 42 through a pipeline, the conducting direction of the second one-way valve 42 points to the disinfecting cylinder 32, a disinfecting cotton sleeve 45 is sleeved inside the disinfecting cylinder 32, the puncture needle 33 can sequentially penetrate through the upper end surface of the disinfecting cylinder 32, the disinfecting cotton sleeve 45 and the center of the flange cover 36, and the puncture needle 33 can slide on the upper end surface of the disinfecting cylinder 32, the disinfecting cotton sleeve 45 and the flange cover 36.

In this embodiment, as shown in fig. 1 and 2, the positioning mechanism includes a screw 13, the screw 13 is parallel to the cross support plate 14, the screw 13 is located above the cross support plate 14, the screw 13 is screwed into a threaded hole 29 formed in the upper end of the vertical rod 4, one end of the screw 13 pointing to the spherical hinge seat 15 is slidably connected to a through hole 30 formed in the spherical hinge seat 15, one end of the screw 13 pointing to the spherical hinge seat 15 can be in abutting contact with the spherical ball 16, a second sleeve 40 is sleeved on the screw 13 located on the left side of the spherical hinge seat 15, the second sleeve 40 can rotate on the screw 13, second collars limiting the second sleeve 40 are disposed on two sides of the second sleeve 40, the second collars are fixed on the screw 13, and the second sleeve 40 is fixedly connected to the left end of the ejector rod 39.

In this embodiment, as shown in fig. 1 and 2, the positioning mechanism further includes a guide sleeve 8 fixed on the vertical rod 4, a compression rod 7 is slidably connected inside the guide sleeve 8, the compression rod 7 is parallel to the vertical rod 4, a lower end of the compression rod 7 penetrates through the corresponding sliding frame 3 and is located in a groove 5 formed in the sliding frame 3, the compression rod 7 can slide up and down on the sliding frame 3, a toothed plate 6 is slidably connected inside the groove 5, a lower surface of the toothed plate 6 can be in abutting-buckling contact with an upper surface of the sliding rail 2, as shown in fig. 5, teeth are formed in the upper surface of the sliding rail 2, the cross section of the sliding rail 2 is T-shaped, an upper end of the compression rod 7 is hinged to a first sleeve 11 through a connecting rod 9, the first sleeve 11 is sleeved on a screw rod 13, the first sleeve 11 can rotate on the screw rod 13, first protruding rings limiting the first sleeve 11 are arranged on two sides of the first sleeve.

The use method and the advantages of the invention are given below, and when the small animal experiment blood sampling device is used, the small animal experiment blood sampling device comprises the following steps:

the method comprises the following steps: as shown in fig. 2, at this time, in an initial state, the screw 13 is not in contact with the ball 16, the pump barrel 37 is filled with disinfectant, the toothed plate 6 is not in contact with the upper surface of the corresponding slide rail 2, the cylinder 21 is in an extended state, a white mouse needing blood collection is bound on the blood collection table 1, as shown in fig. 4, the ball end of the puncture needle 33 in the blood collection device is inserted into the needle clamping barrel 35, and after the ball end of the puncture needle 33 is inserted into the needle clamping barrel 35, the rubber ring 44 is squeezed to enable the rubber ring 44 to be exactly correspondingly buckled with the annular groove 43, the needle clamping barrel 35 is used for fixing the puncture needle 33, the puncture needle 33 is prevented from falling off during blood collection, the installation and disassembly of the puncture needle 33 are facilitated, then the end of the blood discharge needle 28 connected with a hose is buckled on the second clamp 27, the vacuum blood collection tube 26 is buckled on the first clamp 25, and the first clamp 25 and the second clamp 27 are both made of elastic materials, so that the blood discharge needle 28 and, therefore, the operation is convenient, the operation difficulty is reduced, a new disinfection cotton sleeve 45 is sleeved in the disinfection cylinder 32, the disinfection cotton sleeve 45 is used for infiltrating disinfection liquid and disinfecting the puncture needle 33, and the flange cover 36 is used for plugging the lower end of the disinfection cylinder 32, so that the disinfection cotton sleeve 45 is convenient to replace;

after the preparation is completed, the sliding frame 3 is pushed by a hand, so that the sliding frame 3 moves on the sliding rail 2, the T-shaped sliding rail 2 is adopted to enable the sliding frame 3 to move more stably, after the sliding frame 3 moves to a proper position, the ball 16 rotates in the ball hinge seat 15 by rotating the ball 16, so that the ball 16 drives the sliding rod 18 to incline for a certain angle, and the sliding rod 18 synchronously drives the puncture needle 33 to incline for a certain angle, so that a proper needle inserting angle is adjusted during blood sampling, after the needle inserting angle is adjusted, as shown in fig. 1, the rotating disc 10 is held by the hand and the rotating disc 10 is rotated, so that the rotating disc 10 drives the screw 13 to rotate synchronously, the screw 13 moves towards the ball 16 under the action of thread transmission and is in abutting contact with the ball 16, so that the screw 13 extrudes the ball 16, and the ball 16 is fixed in the ball hinge seat 15 by the action of friction force, the ball 16 and the ball hinge seat 15 are connected in a ball hinge mode, so that the adjustment of all directions is convenient, the structure is simple, the adjustment is convenient, and the usability is high;

in the process that the screw 13 moves towards the ball 16, the first sleeve 11 drives the connecting rod 9 to apply downward pressure to the pressing rod 7, so that the pressing rod 7 drives the toothed plate 6 to approach the sliding rail 2, the toothed plate 6 is in abutting and buckling contact with the sliding rail 2, the sliding frame 3 and the sliding rail 2 are fixed, the sliding frame 3 cannot move on the sliding rail 2, and the positioning mechanism keeps the blood sampling mechanism immovable after adjusting the position and the needle inserting angle, so that the blood sampling mechanism is ensured to be kept stable in the blood sampling process, the normal blood sampling is ensured, and the heart of a white mouse is prevented from being damaged in the blood sampling process;

step two: as mentioned above, as shown in FIG. 3, in the process that the screw 13 approaches the ball 16, the screw 13 applies a rightward thrust to the push rod 39 through the second sleeve 40, so that the push rod 39 pushes the piston plate 38 to move rightward, the disinfectant inside the pump cylinder 37 is pressurized, since the conducting direction of the first check valve 41 points to the pump cylinder 37 and the conducting direction of the second check valve 42 points to the disinfection cylinder 32, the disinfectant inside the pump cylinder 37 is transported into the disinfection cylinder 32 through the second check valve 42 and the pipeline, and permeates into the disinfection cotton sleeve 45, so that when the blood sampling mechanism takes a blood sample through a needle, the disinfection cotton sleeve 45 disinfects the puncture needle 33, thereby preventing the heart blood of the white rat from being polluted, and after the blood sampling is finished, the disinfection cotton sleeve 45 can disinfect the puncture needle 33 again when the blood sampling mechanism is withdrawn, and timely wipe the blood adhered to the outer wall of the puncture needle 33, and the sterilization is carried out, so that the adhesion of germs on the blood adhered to the outer wall of the puncture needle 33 is avoided, and the infection is prevented;

step three: after the positioning is finished, the air cylinder 21 is started, the air cylinder 21 retracts a piston rod of the air cylinder 21 to drive the fixed rod 22 and the slide rod 18 to synchronously move downwards along the slide way 17, the slide rod 18 moves downwards to synchronously drive the puncture needle 33 to move downwards through the needle clamping cylinder 35, the puncture needle 33 penetrates through the disinfection cylinder 32 to be disinfected, then the heart of the white rat is pricked, the automatic puncture needle 33 is disinfected before blood collection, the safety of blood collection is improved, germ infection is avoided, the disinfection cylinder 32 has a guiding effect on the puncture needle 33, the accuracy of blood collection is ensured, the blood discharge needle 28 is synchronously driven to move downwards through the two hoops 27 and is inserted into the vacuum blood collection tube 26 when the slide rod 18 moves downwards, and therefore blood in the heart of the white rat enters the vacuum blood collection tube 26 through the puncture needle 33, the hose and the blood discharge needle 28 under the action of vacuum negative pressure in the vacuum blood collection tube 26, the heart of the white rat, the whole process is simple to operate, safe and reliable;

after blood collection is finished, the air cylinder 21 is controlled to work, the air cylinder 21 extends out of a piston rod of the air cylinder to drive the fixed rod 22 and the slide rod 18 to synchronously move upwards and reset along the slide way 17, the slide rod 18 moves upwards to synchronously drive the puncture needle 33 to move upwards and reset through the needle clamping cylinder 35, the puncture needle 33 penetrates through the disinfection cylinder 32 to be disinfected again, the blood discharging needle 28 is synchronously driven to move upwards and pull out from the vacuum blood collection tube 26 through the clamp II 27 while the slide rod 18 moves upwards, automatic needle withdrawing is realized, then the rotary disc 10 is reversely rotated through a hand, the rotary disc 10 drives the screw 13 to synchronously rotate reversely, the screw 13 is driven to be far away from the ball 16 under the action of thread transmission by the reverse rotation of the screw 13, and the ball 16 is not contacted with the ball 16, and therefore the ball 16 can freely rotate in the ball hinge seat 15;

in the process that the screw 13 is far away from the ball 16, the screw 13 applies a leftward pulling force to the ejector rod 39 through the second sleeve 40, so that the ejector rod 39 pulls the piston plate 38 to move leftward, a suction force is generated inside the pump cylinder 37, since the conduction direction of the first check valve 41 points to the pump cylinder 37, and the conduction direction of the second check valve 42 points to the disinfection cylinder 32, the disinfection solution polluted inside the disinfection cylinder 32 is prevented from flowing back into the pump cylinder 37, and under the action of the suction force, the disinfection solution in the disinfection solution tank 12 is conveyed into the pump cylinder 37 through the first check valve 41 and the pipeline, so that automatic supplementation of the disinfection solution is realized, and the puncture needle 33 is disinfected in the next blood sampling;

drive connecting rod 9 through sleeve pipe 11 and exert ascending pulling force to depression bar 7 at the in-process that screw rod 13 kept away from to ball 16, thereby make depression bar 7 drive pinion rack 6 keep away from to slide rail 2, and make pinion rack 6 and slide rail 2 contactless, thereby make balladeur train 3 can move on slide rail 2, then move balladeur train 3 to the direction of keeping away from the mice, thereby be convenient for sew up and unbind the mice, then take off vacuum blood collection tube 26 from clamp one 25, and take off pjncture needle 33 from card syringe 35, take off row's blood needle 28 from clamp two 27 and carry out classification at last, then unscrew flange lid 36 and take out the aseptic cotton cover 45 of pollution, so that change new aseptic cotton cover 45 when next blood sampling, whole process operation is simple and convenient, improve the success rate of taking a blood, save time and labor.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and the preferred embodiments of the present invention are described in the above embodiments and the description, and are not intended to limit the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.