阅读说明：本技术 一种化妆品组合物、化妆品及其制备方法 (Cosmetic composition, cosmetic and preparation method thereof ) 是由 杨钧元 于 2020-06-27 设计创作，主要内容包括：本发明提出了一种化妆品组合物,由以下原料组成：蛹虫草提取物微球、2-(2’-羟基-5’-甲基苯基)苯并三氮唑、六甲基磷酰三胺、月桂氮酮、1,2-丙二醇、植物精油、钛白粉、玉米低聚肽、大豆异黄酮、表面活性剂。本发明还提供一种化妆品及其制备方法。本发明制备方法简单,得到的蛹虫草提取物具有良好的消炎、祛痘的效果,制备的化妆品中的活性物质经过微球保护,待使用时揉搓破裂,保护活性物质活性不被破坏,使用效果好,具有广阔的应用前景。(The invention provides a cosmetic composition, which consists of the following raw materials: cordyceps militaris extract microspheres, 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, hexamethylphosphoric triamide, laurocapram, 1, 2-propylene glycol, plant essential oil, titanium dioxide, corn oligopeptide, soybean isoflavone and surfactant. The invention also provides a cosmetic and a preparation method thereof. The preparation method is simple, the obtained cordyceps militaris extract has good anti-inflammatory and acne-removing effects, the active substances in the prepared cosmetics are protected by the microspheres, and are broken by kneading when the cosmetics are used, so that the activity of the active substances is protected from being damaged, the use effect is good, and the cordyceps militaris extract has a wide application prospect.)

1. A cosmetic composition is characterized by comprising the following raw materials: cordyceps militaris extract microspheres, 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, hexamethylphosphoric triamide, laurocapram, 1, 2-propylene glycol, plant essential oil, titanium dioxide, corn oligopeptide, soybean isoflavone and surfactant;

the cordyceps militaris extract microspheres are prepared by the following method:

s1, preparing a cordyceps militaris extract: cleaning Cordyceps militaris fruiting body, drying, pulverizing to below 200 mesh, adding into glycerol-ethyl acetate-water mixed extractive solution, microwave heating to 60-80 deg.C, extracting for 2-5 hr, filtering, adding filtrate into ethanol to obtain precipitate A and solution, filtering, and collecting precipitate A; removing solvent from the solution under reduced pressure, adding into n-hexane, stirring until precipitate B is generated, filtering to obtain precipitate B, and mixing precipitate A and precipitate B to obtain Cordyceps militaris extract;

s2, preparing cordyceps militaris extract microspheres: continuously stirring the surfactant and the edible oil until the mixture is uniformly mixed, adding the cordyceps militaris extract prepared in the step S1 into a gelatin aqueous solution, after complete dissolution, dropwise adding the cordyceps militaris extract by using a trace liquid adding device, stopping dropwise adding until the system is suddenly changed from clear to turbid, obtaining W/O microemulsion, and then adding methanol for demulsification to obtain cordyceps militaris extract microspheres;

the surfactant is selected from one or more of monoalkyl phosphate ester salt, carboxylate, cocamidopropyl betaine, imidazoline, sorbitan monolaurate, ethylene oxide addition product, polyoxyethylene lauryl ether, cocofatty acid diethanolamide and oleoyl methyl taurate.

2. The cosmetic composition according to claim 1, which is prepared from the following raw materials in parts by weight: 3-5 parts of cordyceps militaris extract microspheres, 0.5-1 part of 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, 0.5-1 part of hexamethylphosphoric triamide, 0.01-0.05 part of laurocapram, 0.01-0.05 part of 1, 2-propylene glycol, 0.5-2 parts of vegetable essential oil, 0.1-1 part of titanium dioxide, 0.5-2 parts of corn oligopeptide, 0.1-2 parts of soybean isoflavone and 1-2 parts of surfactant.

3. The cosmetic composition according to claim 2, which is prepared from the following raw materials in parts by weight: 4 parts of cordyceps militaris extract microspheres, 0.7 part of 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, 0.7 part of hexamethyl phosphoric triamide, 0.03 part of laurocapram, 0.02 part of 1, 2-propylene glycol, 1.2 parts of plant essential oil, 0.6 part of titanium dioxide, 1.2 parts of corn oligopeptide, 1.5 parts of soybean isoflavone and 1.4 parts of surfactant.

4. The cosmetic composition as claimed in claim 1, wherein the plant essential oil is selected from one or more of lavender oil, lemon oil, bergamot oil, clove oil, peppermint oil, cinnamon oil, rose oil, rosemary oil and thyme oil.

5. The cosmetic composition according to claim 1, wherein the volume ratio of glycerol, ethyl acetate and water in the glycerol-ethyl acetate-water mixed extract is (1-3): (2-3): 5; the microwave power is 500-1000W, and the surfactant is one or a mixture of more of monoalkyl phosphate, carboxylate, cocamidopropyl betaine, imidazoline, sorbitan monolaurate, ethylene oxide addition product, polyoxyethylene lauryl ether, cocodiethanolamide and oleoyl methyl taurate; the edible oil is selected from one or more of corn oil, rapeseed oil, soybean oil, olive oil and linseed oil; the gelatin content of the gelatin water solution is 45-65 wt%.

6. A cosmetic comprising the cosmetic composition according to any one of claims 1 to 5 and other auxiliary materials.

7. The cosmetic composition according to claim 6, wherein the cosmetic composition is present in an amount of 2 to 10 wt%.

8. The cosmetic according to claim 6, wherein the other auxiliary materials are composed of the following raw materials: disodium EDTA 2 wt%, phenoxyethanol 1.5 wt%, oxybenzone 2 wt%, salicylate 1.2 wt%, styrene/acrylate copolymer 1.1 wt%, polydimethylsiloxane 0.5 wt%, sorbic acid 0.2 wt%, isobutyl methyl tetrahydropyranol 0.3 wt%, trimethylphenylpropanol 4 wt%, sorbitan isostearate 2 wt%, phenylisohexanol 1.2 wt%, xanthan gum 4 wt%, phytosphingosine 2 wt%, sodium lauroyl lactylate 1 wt%, acetylhydroxyproline 0.2 wt%, palmitoyl pentapeptide-40.5 wt%, beta-glucan 0.2 wt%, hydroxyethyl cellulose 2.2 wt%, allantoin 0.3 wt%, and the balance of deionized water, wherein the mass percentage is the percentage of the total mass of the cosmetic.

9. Use of the cosmetic according to any one of claims 6 to 8 for anti-inflammation and anti-acne treatment.

10. A process for the preparation of a cosmetic product according to any one of claims 6 to 8, comprising the steps of: adding the cosmetic composition of any one of claims 1 to 5 and other adjuvants into a reactor, mixing uniformly, and homogenizing at 10000-.

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to a cosmetic composition, a cosmetic and a preparation method thereof.

Background

At present, cosmetics on the market contain a lot of substances which stimulate the skin, such as essence, preservative and the like, and can damage the skin of consumers after long-term use. Whitening products appearing in the market are often added with heavy metals and other components which are easy to generate side effects, anti-wrinkle and anti-firming products are mainly added with heavy metals, preservatives and other substances to play a role in resisting aging, and the products can cause great harm to human bodies after being used for a long time. Most cosmetics only have one effect, other effects are weak and single, various skin problems cannot be simultaneously considered, and various functions can be realized at a high price.

Cordyceps militaris (Cordyceps militaris), also known as Cordyceps militaris, etc., is a model species of Ascomycotina, Clavipitales, Clavipitaceae, Cordyceps, is widely distributed throughout the world, and is a rare Chinese medicine and high-grade tonic. The active ingredients and functions of the cordyceps sinensis are very similar to those of famous medicinal fungi cordyceps sinensis, the cordyceps sinensis contains various amino acids, vitamins, trace elements, SOD, cordyceps adenosine, cordycepic acid, cordyceps polysaccharide and other bioactive substances, and the contents of the cordyceps adenosine, nucleoside and other substances are higher than those of the cordyceps sinensis, so that the cordyceps sinensis has various physiological functions of enhancing immunity, regulating endocrine, resisting fatigue, resisting oxidation, resisting aging, resisting bacteria, resisting tumors, resisting anoxia, calming, reducing blood sugar, protecting liver, kidney, respiratory system and the like.

Wherein the Cordyceps polysaccharide is polysaccharide composed of mannose, cordycepin, adenosine, galactose, arabinose, saccharin, glucose, and fucose. Experiments prove that the cordyceps polysaccharide can improve the immunologic function of a human body and increase white blood cells, and is clinically used for treating malignant tumors. In addition, Cordyceps can be used for treating pulmonary tuberculosis, short breath, cough and asthma, sexual impotence, nocturnal emission, spontaneous perspiration, night sweat, soreness of waist and knees, and lowering blood sugar. The Cordyceps adenosine mainly comprises uracil, adenine, hypoxanthine, guanine, adenine, etc., and has anti-tumor effect. At present, the method for directly extracting active substances from cordyceps militaris still has the problems of low extraction efficiency and serious damage to the active substances in the extraction process. Therefore, the development and utilization of cordyceps militaris are mostly carried out by extracting active substances in a fermentation mode or on the basis of fermentation. However, the fermentation process lengthens the extraction time and reduces the efficiency of extraction.

Therefore, the cosmetic composition rich in the cosmetics, which is natural in raw materials, free of side effects on skin and good in effect, has a good market prospect.

Disclosure of Invention

The invention aims to provide a cosmetic composition, a cosmetic and a preparation method thereof, the raw materials are natural, no side effect is caused to skin, the obtained cordyceps militaris extract has good anti-inflammation and acne-removing effects, active substances in the prepared cosmetic are protected by microspheres, and are broken by rubbing when the cosmetic is used, so that the activity of the active substances is protected from being damaged, and the using effect is good.

The technical scheme of the invention is realized as follows:

the invention provides a cosmetic composition, which consists of the following raw materials: cordyceps militaris extract microspheres, 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, hexamethylphosphoric triamide, laurocapram, 1, 2-propylene glycol, plant essential oil, titanium dioxide, corn oligopeptide, soybean isoflavone and surfactant;

the cordyceps militaris extract microspheres are prepared by the following method:

s1, preparing a cordyceps militaris extract: cleaning Cordyceps militaris fruiting body, drying, pulverizing to below 200 mesh, adding into glycerol-ethyl acetate-water mixed extractive solution, microwave heating to 60-80 deg.C, extracting for 2-5 hr, filtering, adding filtrate into ethanol to obtain precipitate A and solution, filtering, and collecting precipitate A; removing solvent from the solution under reduced pressure, adding into n-hexane, stirring until precipitate B is generated, filtering to obtain precipitate B, and mixing precipitate A and precipitate B to obtain Cordyceps militaris extract;

s2, preparing cordyceps militaris extract microspheres: continuously stirring the surfactant and the edible oil until the mixture is uniformly mixed, adding the cordyceps militaris extract prepared in the step S1 into a gelatin aqueous solution, after complete dissolution, dropwise adding the cordyceps militaris extract by using a trace liquid adding device until the system is suddenly changed from clear to turbid, stopping dropwise adding to obtain W/O microemulsion, and then adding methanol to demulsify to obtain cordyceps militaris extract microspheres;

the surfactant is selected from one or more of monoalkyl phosphate ester salt, carboxylate, cocamidopropyl betaine, imidazoline, sorbitan monolaurate, ethylene oxide addition product, polyoxyethylene lauryl ether, cocofatty acid diethanolamide and oleoyl methyl taurate.

As a further improvement of the invention, the feed additive comprises the following raw materials in parts by weight: 3-5 parts of cordyceps militaris extract microspheres, 0.5-1 part of 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, 0.5-1 part of hexamethylphosphoric triamide, 0.01-0.05 part of laurocapram, 0.01-0.05 part of 1, 2-propylene glycol, 0.5-2 parts of vegetable essential oil, 0.1-1 part of titanium dioxide, 0.5-2 parts of corn oligopeptide, 0.1-2 parts of soybean isoflavone and 1-2 parts of surfactant.

As a further improvement of the invention, the feed additive comprises the following raw materials in parts by weight: 4 parts of cordyceps militaris extract microspheres, 0.7 part of 2- (2 '-hydroxy-5' -methylphenyl) benzotriazole, 0.7 part of hexamethyl phosphoric triamide, 0.03 part of laurocapram, 0.02 part of 1, 2-propylene glycol, 1.2 parts of plant essential oil, 0.6 part of titanium dioxide, 1.2 parts of corn oligopeptide, 1.5 parts of soybean isoflavone and 1.4 parts of surfactant.

As a further improvement of the invention, the plant essential oil is one or a mixture of more of lavender oil, lemon oil, bergamot oil, clove oil, peppermint oil, cinnamon oil, rose oil, rosemary oil and thyme oil.

As a further improvement of the invention, the volume ratio of the glycerol, the ethyl acetate and the water in the glycerol-ethyl acetate-water mixed extracting solution is (1-3): (2-3): 5; the microwave power is 500-1000W, and the surfactant is one or a mixture of more of monoalkyl phosphate, carboxylate, cocamidopropyl betaine, imidazoline, sorbitan monolaurate, ethylene oxide addition product, polyoxyethylene lauryl ether, cocodiethanolamide and oleoyl methyl taurate; the edible oil is selected from one or more of corn oil, rapeseed oil, soybean oil, olive oil and linseed oil; the gelatin content of the gelatin water solution is 45-65 wt%.

The invention further protects a cosmetic which comprises the cosmetic composition and other auxiliary materials.

As a further improvement of the invention, the cosmetic composition is 2-10 wt% by mass.

As a further improvement of the invention, the other auxiliary materials consist of the following raw materials: disodium EDTA 2 wt%, phenoxyethanol 1.5 wt%, oxybenzone 2 wt%, salicylate 1.2 wt%, styrene/acrylate copolymer 1.1 wt%, polydimethylsiloxane 0.5 wt%, sorbic acid 0.2 wt%, isobutyl methyl tetrahydropyranol 0.3 wt%, trimethylphenylpropanol 4 wt%, sorbitan isostearate 2 wt%, phenylisohexanol 1.2 wt%, xanthan gum 4 wt%, phytosphingosine 2 wt%, sodium lauroyl lactylate 1 wt%, acetylhydroxyproline 0.2 wt%, palmitoyl pentapeptide-40.5 wt%, beta-glucan 0.2 wt%, hydroxyethyl cellulose 2.2 wt%, allantoin 0.3 wt%, and the balance of deionized water, wherein the mass percentage is the percentage of the total mass of the cosmetic.

The invention further protects the application of the cosmetic in the aspects of diminishing inflammation and removing acnes.

The invention further provides a preparation method of the cosmetic, which comprises the following steps: adding the cosmetic composition of any one of claims 1 to 5 and other adjuvants into a reactor, mixing uniformly, homogenizing at 10000-,

the invention has the following beneficial effects: the corn oligopeptide is produced by taking corn protein powder as a raw material and carrying out processes of size mixing, protease enzymolysis, separation, filtration, spray drying and the like, is a new resource product, and can resist oxidation and aging and play a certain whitening effect when being used as a cosmetic additive; soy isoflavones are a class of secondary metabolites formed during the growth of soybeans and are a bioactive substance. Since the soybean isoflavone is extracted from plants and has a structure similar to that of estrogen, the soybean isoflavone is also called phytoestrogen, so that the skin of women is smooth, fine, tender and elastic, and the women can be refreshed. The plant essential oil is extracted from pure plants, and has the effects of diminishing inflammation, inhibiting bacteria and increasing the fragrance of the cosmetics; the titanium dioxide is fine white powder, and has whitening effect when being added into cosmetics;

the cordyceps militaris sporocarp contains rich active substances, namely cordyceps polysaccharide, cordycepic acid and cordycepin, wherein the cordyceps polysaccharide and cordycepic acid can be extracted by water, and the cordycepin can be extracted by an alcoholic solution; the preparation of microemulsion is the first step of synthesizing microsphere, firstly, stable microemulsion with strong uniformity is prepared, then the ideal microsphere can be obtained. Selecting a proper surfactant ratio and a proper microemulsion composition, preparing the microemulsion with high reaction monomer content, and synthesizing microspheres, wherein the microspheres can protect the activity of the cordyceps militaris extract from being oxidized and deteriorated;

the preparation method is simple, the obtained cordyceps militaris extract has good anti-inflammatory and acne-removing effects, the active substances in the prepared cosmetics are protected by the microspheres, and are broken by kneading when the cosmetics are used, so that the activity of the active substances is protected from being damaged, the use effect is good, and the cordyceps militaris extract has a wide application prospect.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

FIG. 1 is a graph showing a comparison of the melanin reduction rates in test example 1 of the present invention;

FIG. 2 is a graph showing a comparison of the reduction ratio of melanin in test example 1 of the present invention;

FIG. 3 is a preparation process diagram of the cosmetic of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.