Method, device and system for inhibiting progression of refractive error of an eye
阅读说明:本技术 抑制眼睛的屈光不正的进展的方法、装置和系统 (Method, device and system for inhibiting progression of refractive error of an eye ) 是由 谢欣然 林小燕 杜嗣河 于 2018-11-06 设计创作,主要内容包括:本发明涉及一种用于延缓或逆转观看者(33,52,83,102)近视进展的方法,还涉及用于这种方法的沉浸式和非沉浸式装置和系统。该方法包括以下步骤:使用沉浸式或非沉浸式装置在观看者(33,52,83,102)的眼睛(210)中创建多个图像平面(234,234’,234”)。当图像平面(234,234’,234”)位于视网膜(22,42,62,92,112,212)上时,至少一个图像平面(234,234’,234”)不在视网膜(22,42,62,92,112,212)上,从而产生近视散焦。(The invention relates to a method for slowing or reversing the progression of myopia in a viewer (33,52,83,102), and to immersive and non-immersive apparatus and systems for use in such a method. The method comprises the following steps: a plurality of image planes (234,234', 234 ") are created in an eye (210) of a viewer (33,52,83,102) using an immersive or non-immersive device. When the image planes (234,234 ', 234 ") are located on the retina (22,42,62,92,112,212), at least one of the image planes (234,234', 234") is not on the retina (22,42,62,92,112,212), thereby producing myopic defocus.)
1. A method for slowing or reversing the progression of myopia in a viewer, the viewer's eye having a retina with a central region, the method comprising the steps of:
A) a non-immersive display unit is provided, comprising:
i) a display;
ii) a refractive lens located proximal to the display;
iii) a total reflection mirror located on the opposite side of the diopter positive lens from the display; and
iv) a semi-transparent mirror remote from the total reflecting mirror;
B) forming primary visual content on the display;
C) refracting the primary visual content through the refractive positive lens to form a primary optical channel;
D) redirecting the primary optical channel with the total reflecting mirror to the semi-transparent mirror;
E) forming secondary visual content to a secondary optical channel directed at the semi-transparent mirror; and
F) converging the primary optical channel and the secondary optical channel into a converging optical channel,
wherein the converging optical channels form a plurality of image planes in the eye, wherein the image planes have a refractive distance therebetween, and wherein the refractive distance between the plurality of image planes is the difference between the optical vergences between the primary optical channel and the secondary optical channel.
2. A method for slowing or reversing the progression of myopia in a viewer of claim 1 wherein the semi-transparent mirror is a thin film mirror.
3. A method for slowing or reversing the progression of myopia in a viewer of claim 1 wherein the base refractive power of the positive refractive lens is from about 10D to about 100D.
4. A method for slowing or reversing the progression of myopia in a viewer according to claim 1 wherein the plurality of image planes produce myopic defocus.
5. A method for slowing or reversing the progression of myopia in a viewer of claim 1, further comprising the steps of: producing myopic defocus.
6. A method for slowing or reversing the progression of myopia in a viewer of claim 1 wherein the plurality of image planes includes a primary image plane including a primary image and a secondary image plane including a secondary image and wherein the primary image is focused on the retina.
7. A method for slowing or reversing the progression of myopia in a viewer of claim 1 wherein the semi-transparent mirror comprises an adjustable reflectivity.
8. A method for slowing or reversing the progression of myopia of a viewer according to claim 1 wherein the secondary visual content is formed by objects distal to the viewer.
9. A method for slowing or reversing the progression of myopia in a viewer according to claim 1 wherein the plurality of image planes produce myopic defocus.
10. A method for slowing or reversing the progression of myopia in a viewer, the viewer's eye having a retina with a central region, the method comprising the steps of:
A) there is provided an immersive display unit comprising:
i) a first display;
ii) a first diopter positive lens located proximal to the first display;
iii) a first total reflection mirror located on an opposite side of the first diopter positive lens from the first display;
iv) a second display;
v) a second diopter positive lens located proximal to the second display;
vi) a semi-transparent mirror on a side of the second diopter positive lens opposite the second display; and
vii) a second total reflector remote from the first total reflector;
B) forming primary visual content on the first display;
C) refracting the primary visual content through the first refractive positive lens to form a primary optical channel;
D) redirecting the primary optical channel with the first total reflecting mirror to the second total reflecting mirror;
E) forming secondary visual content on the second display;
F) refracting the secondary visual content through the second emmetropic lens to form a secondary optical pathway directed toward the semi-transparent mirror;
G) reflecting the secondary optical channel off the semi-transparent mirror;
H) converging the primary optical channel and the secondary optical channel into a converging optical channel; and
I) reflecting the converging optical pathway off the second total reflecting mirror,
wherein the converging optical channels form a plurality of image planes in the eye, wherein the image planes have a dioptric distance therebetween, and wherein the dioptric distance between the plurality of image planes is a maximum difference between the plurality of image planes.
11. A method of slowing or reversing the progression of myopia in a viewer according to claim 10, further comprising:
a third display;
a third diopter positive lens located proximal to the third display; and
a second half mirror on an opposite side of the second diopter positive lens from the second display, and
further comprising the steps of:
forming third visual content on the third display;
refracting the third visual content through the third dioptric positive lens to form a third optical channel directed to the second semi-transparent mirror;
reflecting the third optical channel off the second semi-transparent mirror; and
converging the primary optical channel, the secondary optical channel, and the third optical channel into a converging optical channel.
12. A method for slowing or reversing the progression of myopia in a viewer of claim 10, wherein the refractive distance is the greatest difference between the optical variances between the primary optical channel and the secondary optical channel.
13. A method for slowing or reversing the progression of myopia in a viewer of claim 10 wherein the semi-transparent mirror is a thin film mirror.
14. A method for slowing or reversing the progression of myopia in a viewer according to claim 10 wherein the plurality of image planes produce myopic defocus.
15. A method for slowing or reversing the progression of myopia in a viewer of claim 10 further comprising the step of generating myopic defocus.
16. A method for slowing or reversing the progression of myopia in a viewer of claim 10 wherein the plurality of image planes includes a primary image plane including a primary image and a secondary image plane including a secondary image and wherein the primary image is focused on the retina.
17. A method for slowing or reversing the progression of myopia in a viewer according to claim 10 wherein the plurality of image planes produce myopic defocus.
18. A non-immersive display unit comprising:
A) a display for forming primary visual content;
B) a refractive positive lens located proximal to the display;
C) a total reflection mirror located on a side of the diopter positive lens opposite to the display; and
D) a semi-transparent mirror remote from the total reflection mirror;
wherein the primary visual content is refracted through the positive refractive lens to form a primary optical channel, wherein the total-reflecting mirror redirects the primary optical channel to the semi-transparent mirror, wherein secondary visual content is formed to a secondary optical channel, wherein the secondary optical channel is directed at the semi-transparent mirror, wherein the semi-transparent mirror converges the primary optical channel and the secondary optical channel into a converging optical channel, and wherein the converging optical channel forms a plurality of image planes in the eye.
19. An immersive display unit, comprising:
A) a first display for forming primary visual content;
B) a first diopter positive lens located proximal to the first display;
C) a first total reflection mirror located on an opposite side of the first diopter positive lens from the first display;
D) a second display for forming secondary visual content;
E) a second diopter positive lens located proximal to the second display;
F) a semi-transparent mirror on a side of the second diopter positive lens opposite the second display; and
G) a second total reflecting mirror far away from the first total reflecting mirror,
wherein the primary visual content is refracted through the first emmetropic lens to form a primary optical channel, wherein the first total-reflection mirror redirects the primary optical channel to the second total-reflection mirror, refracts the secondary visual content through the second emmetropic lens to form a secondary optical channel, wherein the secondary optical channel is directed toward the semi-transparent mirror, wherein the semi-transparent mirror reflects the secondary optical channel, wherein the semi-transparent mirror converges the primary optical channel and the secondary optical channel to form a converging optical channel, reflects the converging optical channel away from the total-reflection mirror, and wherein the converging optical channel forms a plurality of image planes in the eye.
20. A display system comprising the non-immersive display unit of claim 18.
21. A display system comprising the immersive display unit of claim 19.
Technical Field
The present invention relates to methods and systems for inhibiting the development or progression of refractive error of an eye, with emphasis on myopia and/or hyperopia.
Background
Myopia and hyperopia are common refractive errors of the human eye. Objects beyond a certain distance of the myope are focused in front of the retina and objects beyond a certain distance of the hyperopic are focused behind the retina, and therefore these objects are considered as blurred images.
Myopia develops when the eye grows larger than the focal length of the eye. Myopia typically progresses in the human eye over time and is typically managed by regularly updated prescriptions for optical lenses, such as corrective lenses and contact lenses. These lenses provide clear vision, but do not impede the progression of myopia. Poor, vision-threatening eye diseases are also associated with high myopia.
Hyperopia is usually congenital, where the eye is not large enough and is shorter than the focal length of the eye. Without proper management, hyperopia may be associated with blurred vision, amblyopia, asthenopia, adaptive dysfunction and strabismus. Hyperopia is usually managed by the prescription of corrective optical lenses that provide temporarily clear vision but do not permanently cure or eliminate the disease.
Therefore, there is a need for new technologies that reduce the economic and social burden caused by refractive errors (such as common myopia and hyperopia) by providing both clear vision and retarding function. Recent scientific publications indicate that the growing size of the eye is affected by optical defocus, which is produced when the image is projected from the retina. The refractive development of the eye is affected by a balance between defocusing in opposite directions. In particular, it is documented that artificially induced "myopic defocus" (an image projected in front of the retina) may hinder further progression of myopia. In this context, a location "in front of the retina" refers to any location between the retina and the lens of the eye, and not on the retina.
WO 2006/034652 To, 4/6/2006 suggests the use of concentric multi-zone bifocal lenses in which myopic defocus is induced both axially and circumferentially for visual objects at all viewing distances. These methods have been shown to be effective in slowing myopia progression in both animal studies and human clinical trials. However, these methods, including prescription and use of specialized lenses, may not be suitable for all individuals. Similar disadvantages apply to other contact lens designs, such as US 7766478B2 by Phillips, published on 8/3 2010; US7832859 to Phillips, published on 11/16/2010; US7503655 to Smith et al, published 3, 17, 2009; and Smith et al US 7025460 published on 11/4/2006.
Both US7503655 and US 7025460 above propose methods of counteracting myopia by manipulating peripheral optics to induce relative peripheral myopic defocus without causing myopic defocus at the central retina. Since defocus protection is known to be directly related to the area of the retinal region exposed to it, its design may not be maximally effective because defocus is not induced on the central retina.
Accordingly, there remains a need for improved methods, devices, apparatuses and/or systems for inhibiting, even potentially reducing or even curing, ametropia of a viewer or user. It is therefore an object of the present invention to replace a dedicated lens with a novel viewing system to overcome or ameliorate at least one of the disadvantages of the prior art, or to provide a useful alternative.
Disclosure of Invention
According to the present invention there is provided a method for slowing or reversing the progression of myopia in a viewer. The viewer's eye has a retina with a central region. The method comprises the following steps: a non-immersive display unit is provided having a display, a diopter lens located proximal to the display, a total reflective mirror located on a side of the diopter lens opposite the display, and a semi-transparent mirror located distal from the total reflective mirror. The method further comprises the following steps: forming primary visual content on a display; the primary visual content is refracted through a ametropic lens to form a primary optical channel, the primary optical channel is redirected with a total internal reflection mirror to a semi-transparent mirror, the secondary visual content is formed to a secondary optical channel directed at the semi-transparent mirror, and the primary optical channel and the secondary optical channel are converged into a converging optical channel. The converging optical channels form a plurality of image planes in the eye. The image planes include a dioptric distance therebetween, and the dioptric distance between the plurality of image planes is a difference between optical vergence between the primary optical channel and the secondary optical channel.
In another embodiment, a method for slowing or reversing progression of myopia in a viewer is provided. The viewer's eye has a retina with a central region. The method comprises the following steps: an immersive display unit is provided having a first display, a first diopter positive lens located proximal to the first display, a first total reflective mirror located on an opposite side of the first diopter positive lens from the first display, a second diopter positive lens located proximal to the second display, a semi-transparent mirror located on an opposite side of the second diopter positive lens from the second display, and a second total reflective mirror distal from the first total reflective mirror. The method further comprises the following steps: the method includes forming primary visual content on a first display, refracting the primary visual content through a first diopter lens to form a primary optical channel, redirecting the primary optical channel with a first total reflector to a second total reflector, forming secondary visual content on a second display, refracting the secondary visual content through a second diopter lens to form a secondary optical channel directed toward the semi-transparent mirror, reflecting the secondary optical channel off the semi-transparent mirror, converging the primary optical channel and the secondary optical channel into a converging optical channel, and reflecting the converging optical channel off the second total reflector. The converging optical channels form a plurality of image planes in the eye. There is a dioptric distance between the image planes, and the dioptric distance between the plurality of image planes is the largest difference between the plurality of image planes.
In another embodiment of the invention, the non-immersive display unit includes a display for forming the primary visual content, a ametropic lens located proximal to the display, a total reflecting mirror located on a side of the ametropic lens opposite the display, and a semi-transparent mirror located distal to the total reflecting mirror. The primary visual contents are refracted through the ametropic lens to form a primary optical channel, and the total reflecting mirror redirects the primary optical channel to the semi-transparent mirror. The secondary visual content is formed to a secondary optical channel, and the secondary optical channel is directed toward the semi-transparent mirror. The semi-transparent mirror converges the primary optical channel and the secondary optical channel into a converging optical channel, and the converging optical channel forms a plurality of image planes in the eye.
In another embodiment of the invention, an immersive display unit includes: the display device comprises a first display for forming primary visual content, a first total reflecting mirror located on the opposite side of the first ametropia lens from the first display, a second display for forming secondary visual content, a second ametropia lens located on the near side of the second display, a semi-transparent mirror located on the opposite side of the second ametropia lens from the second display, and a second total reflecting mirror located far away from the first total reflecting mirror. The primary visual content is refracted through the first diopter lens to form a primary optical channel, and the first total reflecting mirror redirects the primary optical channel to the second total reflecting mirror, causing the secondary visual content to be refracted through the second diopter lens to form a secondary optical channel. The secondary optical channel is directed to the semi-transparent mirror, and the semi-transparent mirror reflects the second optical channel. The semi-transparent mirror converges the primary optical channel and the secondary optical channel into a converging optical channel, which reflects the converging optical channel away from the total reflecting mirror. The converging optical channels form a plurality of image planes in the eye.
Drawings
Examples of the invention will now be described with reference to the accompanying drawings, in which:
FIG. 1A is a diagram illustrating the manner in which a conventional visual display unit is used;
FIG. 1B is a schematic optical diagram of an eye viewing the conventional visual display unit of FIG. 1A;
fig. 2A is a diagram showing an optical system having a transparent layer;
FIG. 2B is a schematic optical diagram of an eye viewing the transparent layer of the optical system of FIG. 2A, showing the resulting myopic defocus;
FIG. 3A is a diagram showing a portable system having the optical system of FIG. 2A;
FIG. 3B is a schematic optical diagram of an eye viewing the portable system of FIG. 3A, showing the resulting myopic defocus;
fig. 4A is a diagram showing a manner of an optical system having a reflective layer;
FIG. 4B is a schematic optical diagram of an eye viewing the optical system of FIG. 4A, showing the resulting myopic defocus;
FIG. 5A is a diagram showing a portable system having the optical system of FIG. 4A;
FIG. 5B is a schematic optical diagram of an eye viewing the portable system of FIG. 5A, showing the resulting myopic defocus;
fig. 6 is a diagram of a portable visual display unit employing a transparent or reflective layer and contrast enhancement techniques. Shading indicates a transparent or reflective layer;
FIG. 7 is a schematic optical diagram of an eye viewing the optical system of FIG. 2A, showing the resulting hyperopic defocus;
FIG. 8 is a schematic optical diagram of an embodiment of a non-immersive display unit of the invention;
fig. 9 is a schematic optical diagram of an embodiment of an immersive display unit of the invention; and
FIG. 10 is a schematic view of an embodiment of an electronic control system that may be used herein.
The figures herein are not necessarily drawn to scale.
Detailed Description
Those skilled in the art understand that as used herein, names such as "first," "second," "primary," "secondary," etc. are for clarity and to indicate relative order and grouping, and are not intended to be limiting in any way.
As used herein, the terms "viewer" and "user" are synonymous in that it is the viewer who uses the device and/or system of the present invention.
The present invention relates to a method for preventing, slowing and/or reversing the progression of refractive error of any eye, including myopia or hyperopia of the human eye. In one embodiment herein, the invention relates to a method for preventing the progression of refractive error. In one embodiment herein, the invention relates to a method for delaying the progression of ametropia. In one embodiment herein, the invention relates to a method of reversing ametropia.
There is provided a method for preventing or slowing the progression of myopia comprising producing a focused image on the retina of a human eye for viewing whilst producing a defocused image in front of the retina to produce myopic defocus, as described herein below. In particular, the method includes generating myopic defocus at least over the central region of the retina to achieve a therapeutic effect. To prevent or reduce the progression of hyperopia, the method includes producing a focused image on the retina of a human eye for viewing, and simultaneously producing a defocused image behind the retina to produce hyperopic defocus.
Conventional viewing systems display visual information on a single plane. When viewed, the primary visual objects (such as text and graphics) focus on the retina and do not cause a stimulus of defocus (or hyperopic defocus with a small amount of myopia if the user exhibits habitual lag). The present invention utilizes a transparent or reflective optical layer that allows secondary objects behind or in front of the layer, respectively, to be viewed simultaneously when viewing a primary visual object. Secondary objects located on different planes of refraction are projected in front of the retina to produce a myopic defocus stimulus that retards myopia, or projected behind the retina to produce a hyperopic defocus stimulus that reduces hyperopia.
Transparency is generally defined as the ability of a material to allow light to pass through itself without scattering. In this context, the transparency of a layer is a term in photophysics describing the proportion of light transmitted through the layer, which is quantifiable, adjustable and measurable between 0% and 100%. Thus, the meaning of the term "transparent" is not limited to the literal meaning of completely transparent, but also includes "partially transparent" or "partially transparent or partially transparent". In the context of the present disclosure, the term "transparent" with respect to a layer of material means that about 100% to about 70%, or about 100% to 80%, or about 100% to about 85% of visible light is transmitted through the layer.
Reflectance is generally defined as the percentage of light reflected by a surface. In the present context, the term "reflective" is meant to mean "light reflective". The term is not limited to the literal meaning of complete reflection, but also includes "partial reflection" or "partial reflection or partial reflection".
The transparent layer or the reflective layer mentioned in the embodiments of the present invention may be a physical screen (for transparent or reflective layer) or a virtual imaging plane (for transparent layer) produced by various techniques including, but not limited to, a liquid crystal display, an organic light emitting diode, a screen projection system, a holographic display, a partial mirror, multi-view visualization (multiscopic visualization), volume multiplexing visualization (volume multiplexing visualization), or a combination thereof.
The system referred to in embodiments of the invention may be a permanent home, office or stadium visual display environment, including components such as desktop personal computers, televisions, theater systems, or combinations thereof. The system may also be a compact portable unit or electronic device such as an electronic book reader, tablet computer, portable display, portable computer, other media or gaming system.
Described herein are a number of non-limiting examples for slowing or reversing the progression of refractive error, with emphasis on myopia of the human eye. The apparatus used to perform the method alters the defocus balance of the eye to affect three-dimensional eye growth in the emmetropic direction. In particular, myopic defocus is induced in the eye to retard the progression of myopia. The introduction of myopic defocus is important when normal vision tasks can be maintained throughout the treatment. This means that a focused image can be maintained on the central retina during treatment. The transparent or reflective layer in the form of a visual display unit provides a platform for projecting various primary visual content, which in turn will form a focused image on the retina. At the same time, the transparency or reflectivity of the layer allows viewing of the secondary object. Areas of the layer that do not provide primary visual content may provide transparency or reflectivity. Alternatively, the objects comprising the text or graphics themselves may also be partially transparent or reflective, so that the viewer may view any other object directly behind the transparent object or in front of the reflective object as an overlapping defocused image. Regardless of how transparency or reflectivity is provided, the primary visual content (e.g., text, graphics) on the layer plays a dual key role, becoming the subject of interest and providing the necessary visual cues for the viewer to lock in their ocular accommodation and focus on the plane of the transparent or reflective layer. A separate transparent or reflective layer will not serve as an effective target for the viewer to lock his accommodation and will not perform the desired function unless visual content is displayed thereon. According to optical principles, an object viewed behind the transparent layer or in front of the reflective layer will be projected in front of the retina. Thus, this is an effective means of providing both a clear field of view and myopic defocus. Further, an advantage of the system and method herein is that it does not involve the use of specialized lenses and thus can be widely applied to children and young adults.
Fig. 1A illustrates a manner in which a conventional visual display unit is generally installed and used for viewing. In contrast to, for example, 31 in fig. 2A or 81 in fig. 4A, conventional
In a first embodiment of the invention, a method is provided for introducing a secondary defocused image in front of the retina while introducing a focused image on the retina as a primary image that is continuously brought to the attention of the viewer through the transparent layer. Referring to fig. 2A, this is achieved by providing an object such as a
In one or more of the methods herein, the goal is to stop the progression of and/or cure refractive error of the eye by encouraging the viewer's eye to stop growing in one direction, encouraging the viewer's eye to grow in another direction, and/or growing the viewer's eye to a better shape. Thus, to increase effectiveness, the methods herein may require repeated, continuous use by the viewer for an extended period of time, e.g., more than 1 week, or about 1 week to 15 years; or from about 1 month to about 10 years; or from about 2 months to about 7 years. In one embodiment herein, the methods herein comprise repeatedly viewing the system herein over a period of about 3 months to about 5 years.
In one embodiment herein, the object used to generate the secondary image is a fixed or variable wallpaper showing a landscape such as a forest or mountain or a picture such as that shown in fig. 2A. Preferably, such a picture contains visual content with sufficient contrast and a range of spatial frequencies, which is proven as a prerequisite for the myopic defocus detected by the eye to be corrected. (Tse, Chan et al 2004; Diether and Wildsoet 2005). In particular, it is preferred that the picture contains visual content with a contrast greater than 10%, or preferably about 25% to about 75%, as measured by image capture using a camera and then quantifying pixel brightness levels. It is also preferable that the spatial frequency range included in the picture is 0.02-50 cycles/degree, which is measured by image capturing using a camera, and then spatial frequency analysis using discrete fourier transform. The preferred optical distance between the layer providing the primary image and the object providing the secondary image is about 0.25 to about 6 diopters, or about 0.5 to about 4 diopters, or about 2 to about 3 diopters. The optical distance can be measured by quantifying the power of the lens needed to counteract the defocus, or by measuring the physical dimensions of all optical components, followed by ray tracing.
In one embodiment herein, the level of myopic or hyperopic defocus is specifically tailored to combat the level of myopia or hyperopia of the viewer, particularly for example where the system is provided on a device such as a tablet, personal computer, smartphone, or the like, typically for use by a single person.
Referring to fig. 2B, a viewer typically uses eye accommodation to intentionally focus the primary image displayed by
The embodied optical system may be further modified, for example, it may comprise a visual display unit having more than one transparent layer. The primary visual content may be displayed on the front transparent layer as a primary image for continuous viewing by a user. The secondary visual content forming the secondary image as a visual cue of myopic defocus may be displayed on at least one rear layer used to construct the defocused image without requiring the user's attention.
Fig. 3A shows a simplified optical system having a single transparent layer as a visual display. The system is embodied in a compact form of a portable electronic device such as an electronic book reader unit 51. In embodiments herein, the portable electronic devices herein may include e-book readers, mobile phones, electronic tablets, computers, personal digital assistants, watches, headwear, glasses, wireless displays, holographic projectors, holographic screens, augmented reality devices, virtual reality devices, and combinations thereof. The transparent layer, which acts as a display screen, is positioned and controlled in a position perpendicular to the viewer 52 by a mechanical support structure, such as a frame 53, which becomes portable when folded. The support structure may be permanently or temporarily attached to the transparent layer. The random object 54 may appear in the background environment behind the cell 51. Depending on the viewer's existing refractive error, conventional spectacle correction (not shown) may be required to focus the primary image on the retina.
Referring to fig. 3B, the viewer applies ocular accommodation to focus the primary image displayed by the transparent layer. As a result, visual content, such as text and graphics shown on transparent layer 60, is projected as a focused primary image 61 on retina 62. Random visual objects 63 and 65 enter the field of view of the viewer when the user carries and uses the unit in different visual environments. The viewer can see object 63 behind transparent layer 60 as secondary image 66 and is projected to form a myopic defocused image in front of central retina 64. These defocused secondary images serve as the primary source of myopic defocus 67 signals for slowing the progression of myopia. Other objects 65 in the peripheral field that are further from the unit may also project a secondary image 66 of myopic defocus on other parts of the retina. These images also serve as a secondary source of myopic defocus 67 for slowing myopia progression. Preferably, the transparency of the transparent layer is manually and/or automatically adjustable to control the amount of background objects to be viewed.
Alternatively, in embodiments herein, the optical system (e.g., element 51 of fig. 3A) may be an electronic device that produces the primary image and the secondary image on the same or different layers, e.g., providing both a focused primary image and a defocused secondary image on the same display screen.
Preferably, the transparency of the display screen of the unit 51 is adjustable, and more preferably controllable, for example by electronic means such as transparent organic light emitting diodes, to maintain and optimize the clarity of the visual content in different environments according to personal preferences.
In another embodiment of the invention, a method is provided for introducing myopic defocus by providing a layer having a reflective surface facing a viewer, at least one object facing the reflective surface, and then a primary image having visual content such as text and graphics on the layer, which primary image is viewable by the viewer. Likewise, the object may be a physical object and/or an image of an object. The reflective surface allows the viewer to treat the reflection of the object as a secondary image, and the secondary image is focused in front of the central region of the viewer's retina. The object may be located behind the viewer and/or between the viewer and the reflective surface.
In one embodiment herein, the reflective layer may be a visual display unit adapted to provide a primary image of primary visual content. Referring to fig. 4A, the method herein includes the steps of: an
Referring to fig. 4B, the viewer intentionally focuses the primary image displayed by layer 90 using eye accommodation. Depending on the viewer's existing refractive error, conventional spectacle correction (not shown) may be required to properly focus the primary image on the retina. The primary image displayed on the anterior layer 90 is projected in the eye as a focused image 91, located in the central region of the
Preferably, the light reflectivity of the reflective surface is adjustable in order to control the sharpness of the primary object to be viewed. As shown in fig. 4A, the
The optical system as described above may be further modified. For example, it may comprise a visual display unit having more than one layer. The primary visual content is displayed on the front layer as a primary image for continuous viewing by the user. The secondary visual content forming the secondary image as visual cues of myopic defocus is displayed on at least one posterior layer used to construct the defocused image without requiring the user's attention.
Fig. 5A shows a simplified optical system with a single reflective layer as a visual display. The system is implemented in a compact form of a portable electronic device such as an electronic
Preferably, the light reflectivity of the reflective surface of the
FIG. 6 depicts an example of an electronic book reader unit 130 employing a transparent or reflective display layer embodied in the present invention. Unit 130 uses contrast enhancement techniques to prevent the displayed text or graphics from losing readability due to confusion from out-of-focus images of objects behind the layer. For example, in one embodiment, an organic light emitting diode display may be used to display the primary image. The free area 131 of the layer without text 132 or graphics 133 remains transparent or reflective (as indicated by the shaded portion in the figure). The displayed text or graphic is intentionally surrounded by an edge 134 having a contrasting color relative to the text or graphic to enhance contrast. For example, white text may be surrounded by black edges, or blue text may be surrounded by yellow edges, etc. In one embodiment herein, the primary image (here comprising text) contains at least one edge, and the edge is surrounded by contrasting colors.
The ability of the present invention To treat myopia and hyperopia was supported by applicants' previous studies (Tse and To, 2011) using animal models, which showed that both near-vision defocus and hyperopic defocus can be introduced into the eye by a bi-layer viewing system. In this study, the front layer of the two-layer system was made partially transparent so that the back layer could be seen. If properly controlled, the posterior layer may produce myopic defocus and the anterior layer may produce hyperopic defocus. The results show that the ametropia of the eye is accommodated by the amount of myopic defocus, hyperopic defocus or (more precisely) the ratio between the two, which is produced in a controlled manner by the bilayer system. Thus, by using a transparent layer or a variant thereof as a reflective layer, it seems feasible to apply a similar multi-layer viewing system for treating refractive errors in a person.
Fig. 7 shows another embodiment of the invention relating to an optical system for treating hyperopia. Primary visual content 142 is displayed for viewing by the rear layer 140, while secondary visual content that does not require the attention of the viewer is displayed by the front transparent layer 144. When the user consciously focuses attention on posterior layer 140 using ocular accommodation, the image of primary visual content displayed on posterior layer 140 is projected in the eye as a focused primary image 148. The secondary visual content on the anterior transparent layer 144 is projected in the eye behind the retina 150 as a secondary image 146 of hyperopic defocus. The defocused image serves as the primary source of hyperopic defocus 152 stimulus to promote eye growth and reduce hyperopia.
Fig. 8 is a schematic optical diagram of an embodiment of a
The
In one embodiment herein, the semi-transparent mirror is adjustable. Or adjustable to change the ratio between reflectivity and transparency; or electrochromic, and/or combinations thereof. Adjusting the reflectivity of the semi-transparent mirror; or the ratio between reflectivity and transparency, allows the user to alter the relative intensity of the primary visual content and the secondary visual content, as seen by the eye. Without being limited by theory, it is believed that such adjustable features are particularly useful where, for example, augmented reality embodiments require adjustment for indoor/outdoor situations, bright/dim light situations, and the like.
In fig. 8, secondary
Upon entering the
There is a dioptric distance DD between
Those skilled in the art will appreciate that the dioptric distance DD may be adjusted by adjusting the distance D between the
In the embodiment of fig. 8, the diopter
In one embodiment herein, the base power of the ametropic lens is from about 10D to about 100D. In one embodiment herein, the ametropic lens is adjustable (relative to the baseline diopter) between about +6D and about-6D; or from about +3D to about-3D.
The multiple image planes from embodiments herein produce myopic defocus in the eye of the viewer, thereby slowing or reversing the progression of myopia. Thus, in one embodiment herein, the method further comprises the step of generating myopic defocus.
In one embodiment herein, a controller (see 282 of fig. 10); or software in the controller (see 282 of fig. 10), monitors the system herein to draw the attention of the user's
In one embodiment herein, the level of myopic defocus, ocular accommodation, and combinations thereof are customized for the user or eye. In one embodiment herein, the non-immersive display unit is customized for the eyes of a particular user. In one embodiment herein, a pair of non-immersive display units of the same or different specifications are provided in order to simultaneously slow or reverse the progression of myopia of both eyes of the same user.
In one embodiment herein, the non-immersive display unit herein comprises glasses. In one embodiment herein, a pair of glasses includes a non-immersive display unit herein.
Fig. 9 is a schematic optical schematic of an embodiment of an immersive display unit 250 of the present invention, such as might be useful in, for example, virtual reality headphones or glasses. In this embodiment, the viewer's
A
A
In the embodiment of fig. 9, the primary
The total reflecting mirror 224' "reflects the converging
Typically, there are dioptric distances DD ', DD ", etc. between the image planes 234', 234", 234' "and are determined by the primary
In the embodiment of fig. 9, the ametropia lens 220' is +29D and the distance D ' from the first display 216' is 3cm with respect to the primary
Without being limited by theory, it is believed that the primary
In one embodiment herein, the relative intensity of the myopic defocused image relative to the primary image is controlled by an adjustable semi-transparent mirror.
In one embodiment herein, the present invention provides and/or produces a plurality of myopic defocused images in the eye.
In one embodiment herein, the optical vergence of any optical channel may be fine-tuned, for example, by adjusting the distance D, the diopter of the lens, etc., as shown, for example, in fig. 8 and 9.
In embodiments herein, the various mirrors, displays, lenses, etc. in the immersive display unit are arranged in 3 dimensions, may contain multiple optical channels, etc., and thus do not necessarily adopt the particular arrangement described in fig. 9.
Fig. 10 is a schematic diagram of an embodiment of an
In embodiments herein, the non-immersive display unit is operatively connected to the player to contain and/or for viewing entertainment selected from movies, games, videos, shows, broadcasts, streaming videos, pictures, and combinations thereof; or video, games, and combinations thereof; or a video game.
In fig. 10, the controller is also connected to a
Those skilled in the art will appreciate that, for the sake of brevity, applicants have used the term "myopia" and variations thereof, such as "myopic". Furthermore, for the sake of brevity, applicants use the term "ametropic lens" herein. However, those skilled in the art will also appreciate that the present invention will apply at least equally to viewers. Or a user or eye having a hyperopic/hyperopic state, in which case a refractive negative lens may also be used in the present invention. Moreover, applicants recognize that similar devices and/or methods of treatment for hyperopia are clearly within the scope of the present invention, and that the embodiments of the invention described herein may be readily adapted by those skilled in the art to treat, for example, hyperopia.
The descriptions, drawings, examples, and the like herein are for ease of understanding and should not be construed as limiting the scope of the invention in any way. It is expected that one skilled in the art will be able to devise other embodiments of the present invention based on a complete and complete reading of the specification and the appended claims. All relevant portions of all references cited or described herein are incorporated herein by reference. The inclusion of any reference in no way should be construed as an admission that such reference is available as prior art to the present invention.
Reference documents:
diether, s. and c.f.wildsoet (2005). "Stimulus requirements for the decoding of neurological and hyperopic decoding units and decoding in the chip".Invest Ophthalmol Vis Sci46(7):2242-2252。
Tse, d.y. and c.h.to (2011). "Graded matching regional myocardial and cortical depletion set points in chip"Investigative ophthalmology&visual science52(11):8056-8062。
Tse, y., j.Spatial frequency and myopic defocus detection in chick eye in a closed visual environment。ARVO,Fort Lauderdale.
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