阅读说明：本技术 一种含多种氨基酸的美白牙膏 (Whitening toothpaste containing multiple amino acids ) 是由 许海燕 何威 夏美莲 何智 江风筝 肖小红 谢玲玉 于 2020-06-22 设计创作，主要内容包括：本发明涉及口腔清洁护理用品技术领域,具体为一种含多种氨基酸的美白牙膏,所述含多种氨基酸的美白牙膏由摩擦剂10～20份、保湿剂10～70份、发泡剂2～3份、食用香精0.2～2份、防腐剂0.1～0.5份、粘合剂0.1～0.5份、月桂酰肌氨酸钠0.01～10份、氨基酸0.01～10份、氟化物0.01～1.0份、甜味剂0.1～0.5份、助剂0～0.5份。该含多种氨基酸的美白牙膏,并控制复配体系的ph能很好的保留了牙膏中氟离子的稳定性和精氨酸的活性,同时也能够为牙膏提供发泡的性能,大大提高了此发泡的性能。再通过月桂酰肌氨酸钠与西砒氯铵之间的配合,并控制复配体系的ph能很好的保留了阳离子西砒氯铵的活性,同时也能够为牙膏提供发泡的性能,并且杀灭率达到90％。(The invention relates to the technical field of oral cleaning and nursing products, in particular to a whitening toothpaste containing multiple amino acids, which comprises 10-20 parts of a rubbing agent, 10-70 parts of a humectant, 2-3 parts of a foaming agent, 0.2-2 parts of an edible essence, 0.1-0.5 part of a preservative, 0.1-0.5 part of a binder, 0.01-10 parts of sodium lauroyl sarcosinate, 0.01-10 parts of amino acids, 0.01-1.0 part of fluoride, 0.1-0.5 part of a sweetening agent and 0-0.5 part of an auxiliary agent. The whitening toothpaste containing various amino acids can well keep the stability of fluoride ions and the activity of arginine in the toothpaste by controlling the ph of a compound system, and can provide foaming performance for the toothpaste, thereby greatly improving the foaming performance. And through the matching between sodium lauroyl sarcosine and the arsenic trioxide ammonium and the control of the ph of a compound system, the activity of the cationic arsenic trioxide ammonium can be well kept, meanwhile, the foaming performance can be provided for the toothpaste, and the killing rate reaches 90 percent.)

1. A whitening toothpaste containing various amino acids is characterized in that: the whitening toothpaste containing multiple amino acids comprises 10-20 parts of an abrasive, 10-70 parts of a humectant, 2-3 parts of a foaming agent, 0.2-2 parts of edible essence, 0.1-0.5 part of a preservative, 0.1-0.5 part of a binder, 0.01-10 parts of sodium lauroyl sarcosinate, 0.01-10 parts of amino acids, 0.01-1.0 part of fluorides, 0.1-0.5 part of a sweetening agent, 0-0.5 part of an auxiliary agent and 0.01-0.2 part of arsenic disulfide, and the preparation of the whitening toothpaste containing multiple amino acids comprises the following steps:

the first step is as follows: placing instruments required for preparation, such as a balance, a beaker, a measuring cylinder, a burette, a vacuum machine paste making machine and a glue pot, in a laboratory;

the second step is that: firstly, weighing the medicines according to the dosage of the medicines marked in the formula, putting the adhesive into a glue pot, wetting and stirring to ensure that the prepared glue is in a uniform, semitransparent and sticky liquid state, and then storing to ensure that the glue is fully dissolved and expanded for use;

the third step: firstly, dissolving polyglutamic acid and cetylpyridinium chloride in distilled water, and uniformly stirring to obtain viscous liquid;

the fourth step: adding various friction agents, humectants, foaming agents, preservatives, sodium lauroyl sarcosine, amino acids, fluorides, sweetening agents, auxiliary agents, sodium lauroyl sarcosine, cetylpyridinium chloride, prepared glue and the like into the viscous liquid obtained in the third step according to the formula and operation requirements, mixing and stirring uniformly by a vacuum paste making machine to prepare paste with certain viscosity and proper dilution, adding edible essence into the vacuum paste making machine for stirring, grinding the paste by a grinding device of the vacuum paste making machine, stirring and grinding at high speed for 30 minutes, and degassing;

degassing and standing the paste for a period of time to obtain the product.

2. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the abrasive is one or more of stone powder, silicon dioxide, calcium bicarbonate, calcium hydrogen phosphate and aluminum hydroxide.

3. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the humectant is one or more of glycerol, sorbitol, propylene glycol and polyethylene glycol.

4. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the foaming agent is one or more of lauryl sodium sulfate and cocamidopropyl betaine.

5. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the preservative is one or more of sodium benzoate, DMDMH and nipagin ester.

6. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the adhesive is one or more of sodium carboxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl guar gum, xanthan gum, carrageenan, carbomer resin, magnesium aluminum silicate and poloxamer.

7. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the amino acid is one or more of arginine, glutamic acid, aspartic acid and glycine.

8. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the sweetener is one or more of saccharin sodium, aspartame, stevioside, sucralose, erythritol and xylitol.

9. The whitening toothpaste containing a plurality of amino acids according to claim 1, wherein: the auxiliary agent is one or more of sodium bicarbonate, sodium carbonate and sodium silicate.

Technical Field

The invention relates to the technical field of oral cleaning and nursing products, in particular to whitening toothpaste containing multiple amino acids.

Background

The diseases of teeth and periodontium are caused by the problems of oral hygiene, people hope to achieve the purposes of maintaining oral health, protecting teeth, preventing decayed teeth and maintaining periodontium and gingival tissues through daily oral cleaning and nursing, the factors causing decayed teeth mainly comprise cariogenic bacteria and dental plaque, food and environment of teeth, etc., cariogenic bacteria mainly refer to bacteria having cariogenic ability adhering to tooth surfaces, which produce and secrete harmful chemical substances such as organic acids, polysaccharides, proteolytic enzymes, etc., causing inorganic matter dissolution of tooth hard tissues and subsequent decomposition of organic components, and a large amount of evidence has shown that the existence of bacteria is a necessary condition for the occurrence of caries, dental plaque is an ecological environment for metabolism and treatment of bacteria on tooth surfaces, provides a condition for the action of bacteria, and the inflammation of gum caused by periodontitis, gingivitis, etc., are also caused by the action of bacteria.

Amino acid is one of natural ingredients of human saliva, can be used as a substrate to participate in the process of producing ammonia through bacterial metabolism, the pH value of the oral environment is improved, caries can be prevented, the research on the amino acid is numerous at present, certain amino acid toothpastes in the market are only added with amino acid surfactants, the specific application of the amino acid in the toothpastes is very little, the existing toothpastes have irritation, do not have an obvious effect on chronic xerostomia, are not very good in foaming performance, are not very remarkable in whitening effect, and do not have the functions of clearing heat and removing fire.

Disclosure of Invention

Aiming at the defects of the prior art, the invention provides whitening toothpaste containing various amino acids, which solves the problems of irritation, no obvious effect on chronic xerostomia, poor foaming performance, insignificant whitening effect and no function of clearing heat and reducing internal heat.

In order to achieve the purpose, the invention provides the following technical scheme: a whitening toothpaste containing various amino acids is characterized in that: the whitening toothpaste containing multiple amino acids comprises 10-20 parts of an abrasive, 10-70 parts of a humectant, 2-3 parts of a foaming agent, 0.2-2 parts of edible essence, 0.1-0.5 part of a preservative, 0.1-0.5 part of a binder, 0.01-10 parts of sodium lauroyl sarcosinate, 0.01-10 parts of amino acids, 0.01-1.0 part of fluorides, 0.1-0.5 part of a sweetening agent, 0-0.5 part of an auxiliary agent and 0.01-0.2 part of arsenic disulfide, and the preparation of the whitening toothpaste containing multiple amino acids comprises the following steps:

the first step is as follows: placing instruments required for preparation, such as a balance, a beaker, a measuring cylinder, a burette, a vacuum machine paste making machine and a glue pot, in a laboratory;

the second step is that: firstly, weighing the medicines according to the dosage of the medicines marked in the formula, putting the adhesive into a glue pot, wetting and stirring to ensure that the prepared glue is in a uniform, semitransparent and sticky liquid state, and then storing to ensure that the glue is fully dissolved and expanded for use;

the third step: firstly, dissolving polyglutamic acid and cetylpyridinium chloride in distilled water, and uniformly stirring to obtain viscous liquid;

the fourth step: adding various friction agents, humectants, foaming agents, preservatives, sodium lauroyl sarcosine, amino acids, fluorides, sweetening agents, auxiliary agents, sodium lauroyl sarcosine, cetylpyridinium chloride, prepared glue and the like into the viscous liquid obtained in the third step according to the formula and operation requirements, mixing and stirring uniformly by a vacuum paste making machine to prepare paste with certain viscosity and proper dilution, adding edible essence into the vacuum paste making machine for stirring, grinding the paste by a grinding device of the vacuum paste making machine, stirring and grinding at high speed for 30 minutes, and degassing;

degassing and standing the paste for a period of time to obtain the product.

Preferably, the abrasive is one or more of stone powder, silicon dioxide, calcium bicarbonate, calcium hydrogen phosphate and aluminum hydroxide.

Preferably, the humectant is one or more of glycerol, sorbitol, propylene glycol and polyethylene glycol.

Preferably, the foaming agent is one or more of sodium dodecyl sulfate and cocamidopropyl betaine.

Preferably, the preservative is one or more of sodium benzoate, DMDMH and paraben.

Preferably, the adhesive is one or more of sodium carboxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl guar gum, xanthan gum, carrageenan, carbomer resin, magnesium aluminum silicate and poloxamer.

Preferably, the amino acid is one or more of arginine, glutamic acid, aspartic acid and glycine.

Preferably, the sweetener is one or more of saccharin sodium, aspartame, stevioside, sucralose, erythritol and xylitol.

Preferably, the auxiliary agent is one or more of sodium bicarbonate, sodium carbonate and sodium silicate.

The beneficial effects are as follows:

the whitening toothpaste containing various amino acids has the effect of protecting living cells by adding glutamic acid, has an obvious effect on chronic xerostomia, well maintains the stability of fluoride ions and the activity of arginine in the toothpaste by matching sodium lauroyl sarcosine with fluoride and arginine respectively and controlling the ph of a compound system, and simultaneously can provide foaming performance for the toothpaste, and greatly improve the foaming performance. And through the matching between sodium lauroyl sarcosine and the arsenic trioxide ammonium and the control of the ph of a compound system, the activity of the cationic arsenic trioxide ammonium can be well kept, meanwhile, the foaming performance can be provided for the toothpaste, and the killing rate reaches 90 percent.

Detailed Description

All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The invention provides a technical scheme that: the whitening toothpaste containing multiple amino acids is prepared from 10-20 parts of an abrasive, 10-70 parts of a humectant, 2-3 parts of a foaming agent, 0.2-2 parts of edible essence, 0.1-0.5 part of a preservative, 0.1-0.5 part of a binder, 0.01-10 parts of sodium lauroyl sarcosinate, 0.01-10 parts of amino acids, 0.01-1.0 part of fluoride, 0.1-0.5 part of a sweetening agent, 0-0.5 part of an auxiliary agent and 0.01-0.2 part of arsenic disulfide, and comprises the following steps:

the first step is as follows: placing instruments required for preparation, such as a balance, a beaker, a measuring cylinder, a burette, a vacuum machine paste making machine and a glue pot, in a laboratory;

the second step is that: firstly, weighing the medicines according to the dosage of the medicines marked in the formula, putting the adhesive into a glue pot, wetting and stirring to ensure that the prepared glue is in a uniform, semitransparent and sticky liquid state, and then storing to ensure that the glue is fully dissolved and expanded for use;

the third step: dissolving polyglutamic acid and arsenic trioxide chloramine in distilled water, and stirring uniformly to obtain viscous liquid;

the fourth step: adding various friction agents, humectants, foaming agents, preservatives, sodium lauroyl sarcosine, amino acids, fluorides, sweeteners, auxiliaries, sodium lauroyl sarcosine, arsenic chloramine, prepared glue and the like into the viscous liquid obtained in the third step according to the formula and operation requirements, mixing and stirring uniformly by using a vacuum paste making machine to prepare paste with certain viscosity and proper dilution, adding edible essence into the vacuum paste making machine to stir, grinding the paste by using a grinding device of the vacuum paste making machine, grinding coarse and hard particles to make the paste fine, uniform and stable, wherein the grinding can be carried out twice, the paste is stored after the first grinding, and the vacuum degassing is carried out after the second grinding until the vacuum degree reaches-0.096 MPa for 40-60 minutes;

degassing and standing the paste for a period of time to obtain the product.

The abrasive is one or more of stone powder, silicon dioxide, calcium bicarbonate, calcium hydrogen phosphate and aluminum hydroxide, the humectant is one or more of glycerol, sorbitol, propylene glycol and polyethylene glycol, the foaming agent is one or more of sodium dodecyl sulfate and cocamidopropyl betaine, the preservative is one or more of sodium benzoate, DMDMH and nipagin ester, the binder is one or more of sodium carboxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl guar gum, xanthan gum, carrageenan, carbomer resin, magnesium aluminum silicate and poloxamer, the amino acid is one or more of arginine, glutamic acid, aspartic acid and glycine, the sweetening agent is one or more of saccharin sodium, aspartame, stevioside, sucralose, erythritol and xylitol, and the auxiliary agent is one or more of sodium bicarbonate, sodium carbonate and sodium silicate.