阅读说明：本技术 一种治疗鼻炎的药物组方和制备方法 (Medicine formula for treating rhinitis and preparation method ) 是由 刘启孝 于 2020-07-09 设计创作，主要内容包括：本发明公开了一种治疗鼻炎的药物组方和制备方法,该药物组方,按重量份计,由以下原料制备而成：冰片2份,锌氧粉6份,花生油1份,麝香1份。该药物组方的制备方法为：将锌氧粉加入到花生油中,进行搅拌,使锌氧粉均匀的分散在花生油中,生成混合油,将冰片与麝香加入制备的混合油中,充分搅拌使冰片和麝香均匀分散在所述混合油中,制备成滴鼻油,在滴鼻油中的成分处于均匀分散的状态下进行分瓶罐装。本发明的治疗鼻炎的药物组方和制备方法通过用冰片、麝香配伍加强传统中医治疗鼻炎的通窍方向,将锌氧粉与花生油反应生成油酸锌盐,从而使得药物组方能对鼻粘膜进行修复和保护,进而达到通鼻窍护粘膜、标本兼治的目的。(The invention discloses a medicine formula for treating rhinitis and a preparation method thereof, wherein the medicine formula is prepared from the following raw materials in parts by weight: 2 parts of borneol, 6 parts of zinc oxide powder, 1 part of peanut oil and 1 part of musk. The preparation method of the medicine formula comprises the following steps: adding zinc oxide powder into peanut oil, stirring to uniformly disperse the zinc oxide powder in the peanut oil to generate mixed oil, adding borneol and musk into the prepared mixed oil, fully stirring to uniformly disperse the borneol and the musk in the mixed oil to prepare the nasal drop oil, and bottling and canning under the condition that the components in the nasal drop oil are uniformly dispersed. According to the medicine formula for treating rhinitis and the preparation method, borneol and musk are combined to strengthen the orifice opening direction of traditional Chinese medicine for treating rhinitis, and zinc oxide powder and peanut oil react to generate zinc oleate, so that the medicine formula can repair and protect nasal mucosa, and further achieve the purposes of opening the orifice, protecting the mucosa and treating both symptoms and root causes.)

1. The medicine formula for treating rhinitis is characterized by being prepared from the following raw materials in parts by weight:

2 parts of borneol,

6 parts of zinc oxide powder, namely zinc oxide powder,

1 part of peanut oil, namely 1 part of peanut oil,

musk 1 part.

2. A method of preparing a pharmaceutical formulation according to claim 1, comprising the steps of:

s1, adding 6 parts of zinc oxide powder into 1 part of peanut oil by weight, and stirring to uniformly disperse the zinc oxide powder in the peanut oil to generate mixed oil;

s2, adding 2 parts of borneol and 1 part of musk into the mixed oil prepared in the step S1, and fully stirring to uniformly disperse the borneol and the musk into the mixed oil to prepare nasal drop oil;

s3, bottling and canning the components in the nasal drop oil in a uniformly dispersed state.

3. The method of claim 2, wherein the sub-packaging is accomplished no more than two hours after the nasal oil drops are prepared.

4. The method of claim 2, wherein the zinc oxide powder is reacted in step S1 by contacting with unsaturated fatty acid contained in peanut oil.

5. The method according to claim 4, wherein the mixed oil contains zinc oleate and zinc stearate.

Technical Field

The invention relates to the technical field of medicines, in particular to a medicine formula for treating rhinitis and a preparation method thereof.

Background

In modern life, besides various solid or liquid wastes which can be seen by naked eyes, invisible gas and toxic and harmful tiny particles floating in the air become an increasingly important reason for rhinitis patients. The nasal cavity is a necessary channel for exchanging air between a human body and the outside, and under normal conditions, the nasal cavity regulates and controls the temperature and humidity of the inhaled air, and adheres and discharges solid particles in the air out of the body through mucous membranes and cilia in the nasal cavity. But the development of modern civilization has driven smaller and smaller particles; a large amount of toxic and harmful tiny particles can not be discharged by cilia of the nasal cavity, and are adhered to the mucosa of the nasal cavity for a long time to form infection or directly stimulate the body to form various inflammatory or allergic symptoms.

In the field of rhinitis treatment, western medicines mainly take antibiotics and antiallergic drugs, and traditional Chinese medicines and Chinese patent medicines mainly take orifice-opening drugs such as siberian cocklebur, biond magnolia flower, centipeda minima and the like. The corresponding treatment method can improve rhinitis symptoms such as running nose, nasal obstruction and the like, but the nasal mucosa can not be repaired, and the injury to the nasal mucosa is deepened once for each attack of the rhinitis, which is one of the reasons that the rhinitis repeatedly attacks and the attack frequency is higher and higher.

Disclosure of Invention

Aiming at the technical problems in the related art, the invention provides a medicine formula for treating rhinitis and a preparation method thereof, which can overcome the defects in the prior art.

In order to achieve the technical purpose, the technical scheme of the invention is realized as follows:

the medicine formula for treating rhinitis is prepared from the following raw materials in parts by weight:

2 parts of borneol,

6 parts of zinc oxide powder, namely zinc oxide powder,

1 part of peanut oil, namely 1 part of peanut oil,

musk 1 part.

According to another aspect of the present invention, there is provided a method of preparing a pharmaceutical formulation for the treatment of rhinitis, the method comprising the steps of:

s1, adding 6 parts of zinc oxide powder into 1 part of peanut oil by weight, and stirring to uniformly disperse the zinc oxide powder in the peanut oil to generate mixed oil;

s2, adding 2 parts of borneol and 1 part of musk into the mixed oil prepared in the step S1, and fully stirring to uniformly disperse the borneol and the musk into the mixed oil to prepare nasal drop oil;

s3, bottling and canning the components in the nasal drop oil in a uniformly dispersed state.

Further, the nasal oil is prepared and placed for no more than two hours to complete split charging.

Further, in step S1, the zinc oxide powder is fully contacted with the unsaturated fatty acid contained in the peanut oil to react.

Furthermore, the mixed oil contains zinc oleate salt and zinc stearate salt.

The formula principle is as follows:

the theory of traditional Chinese medicine: the function of borneol is mainly to induce resuscitation, refresh mind, clear heat and alleviate pain. The musk has the functions and main indications of inducing resuscitation and refreshing mind, activating blood and dredging channels, and relieving swelling and pain. The borneol and the musk are combined to strengthen the effect of opening orifices and inducing resuscitation, and can effectively improve the symptoms of nasal obstruction of rhinitis patients.

Modern research:

musk: in modern researches, musk has the effects of reducing blood pressure, increasing heart rate, resisting inflammation, having androgen-like effect, enhancing immunity, inhibiting platelet aggregation, resisting snake venom, histamine, tumors and the like. The anti-inflammatory and antihistamine effects of musk are mainly utilized in the formula, and various symptoms of nasal discharge, nasal obstruction, sneeze and the like of rhinitis patients are related to inflammatory symptoms of nasal mucosa; the antihistaminic effect is beneficial to improving uncomfortable symptoms caused by nasal mucosa allergy of patients with allergic rhinitis.

Borneol: in modern researches, borneol is mainly used for resisting bacteria and diminishing inflammation and promoting transdermal absorption of other medicines. The antibacterial and anti-inflammatory effects of the borneol in the formula improve various bacterial infections of rhinitis patients caused by the long-term inflammatory symptoms of nasal mucosa, and the borneol can effectively kill various bacteria such as staphylococcus aureus, beta hemolytic streptococcus, green streptococcus and the like.

Zinc oxide powder and peanut oil: the zinc oxide powder has the medicinal values of moisture absorption and convergence, and can improve wound surface hydrops and inflammatory symptoms caused by various reasons and protect the skin. In the formula, zinc oxide powder and unsaturated fatty acid in peanut oil generate oleate and stearate, so that the moisture absorption and convergence effects of the zinc oxide powder and the unsaturated fatty acid in peanut oil are maintained, the drug property is delayed, and the stimulation is reduced; can play the drug effect softly and durably at the damaged nasal mucosa, repair and protect the nasal mucosa.

The invention has the beneficial effects that: according to the medicine formula for treating rhinitis and the preparation method, borneol and musk are combined to strengthen the orifice opening direction of traditional Chinese medicine for treating rhinitis, and zinc oxide powder and peanut oil react to generate zinc oleate, so that the medicine formula can repair and protect nasal mucosa, and further achieve the purposes of opening the orifice, protecting the mucosa and treating both symptoms and root causes.

Detailed Description

The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments that can be derived by one of ordinary skill in the art from the embodiments given herein are intended to be within the scope of the present invention.