阅读说明：本技术 眼部胬肉检测定位系统 (Eye pterygium detection positioning system ) 是由 宋贤 于 2020-04-07 设计创作，主要内容包括：本发明涉及一种眼部胬肉检测定位系统,包括：区域切分设备,位于裂隙灯的内部,用于对眼部子图像执行均匀分割以获得各个眼部分区域,并计算组成每一个眼部分区域的各个像素点的各个实时景深值的均值以作为所述眼部分区域的参考景深值；胬肉识别设备,用于在存在某一个眼部分区域,其参考景深值大于整体景深值的幅度超限时,发出胬肉识别信号,并将所述存在的眼部分区域在所述眼部子图像中的相对位置作为胬肉存在位置。本发明的眼部胬肉检测定位系统设计精巧、方便操作。由于在裂隙灯硬件平台上增设眼部胬肉检测定位的辅助功能,从而节省有限的硬件资源,提升眼部胬肉诊断的实时性和可靠性。(The present invention relates to an pterygium detection and localization system, comprising: the region segmentation device is positioned inside the slit lamp and used for uniformly segmenting the eye sub-images to obtain each eye subarea region and calculating the mean value of each real-time depth value of each pixel point forming each eye subarea region to be used as a reference depth value of the eye subarea region; the pterygium identification device is used for sending out pterygium identification signals when a certain eye sub-region exists and the reference depth of field value of the pterygium identification signals is larger than the amplitude limit of the whole depth of field value, and the relative position of the existing eye sub-region in the eye sub-image is used as the pterygium existing position. The eye pterygium detection positioning system is ingenious in design and convenient to operate. Because the auxiliary function of the detection and positioning of the pterygium of the eyes is added on the slit lamp hardware platform, the limited hardware resources are saved, and the real-time performance and the reliability of diagnosis of the pterygium of the eyes are improved.)

1. An pterygium detection and localization system, comprising:

the miniature camera shooting equipment is positioned at the front end of the slit lamp and used for executing camera shooting operation on the environment of the eyes of the human body under the irradiation of the light source of the slit lamp when the slit lamp inspects the eyes of the human body so as to obtain a current eye image;

a superimposition display device embedded in a housing of the slit lamp, for receiving the eye sub-image and the eye portion area where the pterygium exists, and performing highlight red display of the eye portion area based on a relative position of the eye portion area where the pterygium exists in the eye sub-image while displaying the eye sub-image;

the signal filtering equipment is positioned inside the slit lamp, is connected with the miniature camera equipment and is used for executing maximum value filtering processing on the received current eye image so as to obtain a corresponding maximum value filtering image;

the eye segmentation equipment is connected with the signal filtering equipment and used for receiving the maximum value filtering image, and matching and segmenting the eye sub-image corresponding to the eye target from the maximum value filtering image based on the eye appearance characteristic;

the point-by-point detection equipment is connected with the eye segmentation equipment and is used for carrying out depth of field analysis on each pixel point in the eye sub-image so as to obtain a real-time depth of field value of each pixel point and calculating the mean value of the real-time depth of field values of the pixel points forming the eye sub-image to be used as the integral depth of field value of the eye sub-image;

the region segmentation equipment is positioned inside the slit lamp, is connected with the point-by-point inspection equipment, and is used for uniformly segmenting the eye sub-images to obtain each eye sub-region and calculating the mean value of each real-time depth value of each pixel point forming each eye sub-region to be used as the reference depth value of the eye sub-region;

the pterygium identification device is respectively connected with the point-by-point inspection device and the region segmentation device and is used for sending out pterygium identification signals when a certain eye sub-region exists and the reference depth of field value of the certain eye sub-region is larger than the amplitude of the whole depth of field value and exceeds the limit, and outputting the relative position of the existing eye sub-region in the eye sub-image as a pterygium existing position;

and marking the relative position of the existing eye subarea region in the eye subimage by adopting a mode of an abscissa and an ordinate.

2. The eye pterygium detection positioning system of claim 1, further comprising:

the wireless router is respectively in wireless communication connection with the point-by-point detection equipment and the region segmentation equipment through a wireless communication network;

the point-by-point detection device and the area segmentation device are respectively realized by ASIC chips with different models, and are integrated on the same printed circuit board.

3. The pterygium detection positioning system of claim 2, further comprising:

the temperature sensing equipment is respectively connected with the point-by-point detection equipment and the zone segmentation equipment and is used for respectively detecting the shell temperatures of the point-by-point detection equipment and the zone segmentation equipment;

the flash lamp controller is positioned on one side of the miniature camera equipment and is used for controlling the on-off of the flash lamp based on the real-time environment brightness;

wherein controlling the flash to turn on and off based on the real-time ambient brightness comprises: and when the real-time environment brightness is less than or equal to the preset brightness threshold value, the flash lamp is turned on.

4. The eye pterygium detection positioning system of claim 3, wherein:

the flash controller controlling the flash to be turned on and off based on the real-time ambient brightness includes: and when the real-time environment brightness is greater than the preset brightness threshold value, the flash lamp is turned off.

5. The eye pterygium detection positioning system of claim 4, wherein:

the flash controller controlling the flash to be turned on and off based on the real-time ambient brightness includes: and when the real-time environment brightness is less than or equal to the preset brightness threshold, turning on the flash lamp and adjusting the flash brightness of the flash lamp according to the real-time environment brightness, wherein the lower the real-time environment brightness is, the higher the flash brightness of the flash lamp is.

6. The eye pterygium detection positioning system of claim 5, wherein:

the eye segmentation device is internally provided with a storage unit used for storing input data and output data of the eye segmentation device.

7. The eye pterygium detection positioning system of claim 6, wherein:

the point-by-point detection equipment is connected with the IIC control bus and used for receiving various control instructions sent by the IIC control bus.

8. The eye pterygium detection positioning system of claim 7, wherein:

the eye segmentation device is further connected with a clock generator for receiving timing signals customized by the clock generator for the eye segmentation device.

9. The eye pterygium detection positioning system of claim 8, wherein:

the point-by-point detection device is implemented by an ASIC chip, and the ASIC chip comprises an online programming interface.

10. The pterygium detection system of any one of claims 1-9, wherein:

the eye segmentation device and the point-by-point detection device are located on the same printed circuit board and share the same circuit supply device.

Technical Field

The invention relates to the field of medical instruments, in particular to an pterygium detection and positioning system.

Background

Medical instruments refer to instruments, devices, appliances, in-vitro diagnostic reagents and calibrators, materials and other similar or related items used directly or indirectly on the human body, including the required computer software. The effect is mainly obtained through physical and other ways, not pharmacological, immunological or metabolic ways, or only plays an auxiliary role though the ways are involved.

The medical device is used for diagnosing, preventing, monitoring, treating or relieving diseases; diagnosis, monitoring, treatment, mitigation, or functional compensation of injury; examination, replacement, regulation or support of a physiological structure or physiological process; support or maintenance of life; controlling pregnancy; by examining a sample from a human body, information is provided for medical or diagnostic purposes.

The medical appliance industry relates to a plurality of industries such as medicine, machinery, electronics, plastics and the like, and is a high-technology industry with multidisciplinary intersection, knowledge concentration and fund concentration. The basic characteristic of the medical equipment with high and new technology is digitalization and computerization, is the multidisciplinary and cross-field modern high-technology crystal, and has high technical content and high profit, so the equipment is a high-level system for mutual competition of all scientific and technological countries and international large-scale companies, and has higher intervention threshold. Even in the sub-industries with low overall gross profit rate and low investment of the industry, products with high technical content are continuously produced, and some enterprises with high profit capacity are bred from the products. The general industry trend is therefore high investment and high revenue.

The medical imaging equipment is an indispensable component in medical equipment of a hospital, is also an important embodiment of comprehensive strength of the hospital, and not only provides important guarantee for clinical diagnosis and treatment, but also provides an important platform for clinical scientific research. The image device is used as a comprehensive platform and plays an important promoting role in the development of hospitals.

However, in the prior art, pterygium of the patient for seeing a doctor still remains on the basis of manual identification, so that the precision and speed of the mechanism for identifying the pterygium of the eye cannot meet the current requirements of seeing a doctor.

Disclosure of Invention

In order to solve the related technical problems in the prior art, the invention provides an eye pterygium detection positioning system, which can integrate a targeted eye pterygium detection positioning mechanism by using the existing slit lamp, thereby improving the precision of eye pterygium detection and enriching the functions of the existing slit lamp.

Therefore, the invention needs to have the following two key points:

(1) based on the characteristic that the pterygium protrudes out of other areas of the eye, high-precision visual detection and positioning are carried out on the pterygium, and the detection and positioning results are displayed in real time, so that diagnosis of doctors and communication with patients are facilitated;

(2) the pterygium detection positioning mechanism is integrated in the existing slit lamp so as to fully utilize the existing hardware platform.

According to an aspect of the present invention, there is provided an pterygium detection and localization system, the system including:

the miniature camera shooting equipment is positioned at the front end of the slit lamp and used for executing camera shooting operation on the environment of the eyes of the human body under the irradiation of the light source of the slit lamp when the slit lamp inspects the eyes of the human body so as to obtain a current eye image;

a superimposition display device embedded in a housing of the slit lamp, for receiving the eye sub-image and the eye portion area where the pterygium exists, and performing highlight red display of the eye portion area based on a relative position of the eye portion area where the pterygium exists in the eye sub-image while displaying the eye sub-image;

the signal filtering equipment is positioned inside the slit lamp, is connected with the miniature camera equipment and is used for executing maximum value filtering processing on the received current eye image so as to obtain a corresponding maximum value filtering image;

the eye segmentation equipment is connected with the signal filtering equipment and used for receiving the maximum value filtering image, and matching and segmenting the eye sub-image corresponding to the eye target from the maximum value filtering image based on the eye appearance characteristic;

the point-by-point detection equipment is connected with the eye segmentation equipment and is used for carrying out depth of field analysis on each pixel point in the eye sub-image so as to obtain a real-time depth of field value of each pixel point and calculating the mean value of the real-time depth of field values of the pixel points forming the eye sub-image to be used as the integral depth of field value of the eye sub-image;

the region segmentation equipment is positioned inside the slit lamp, is connected with the point-by-point inspection equipment, and is used for uniformly segmenting the eye sub-images to obtain each eye sub-region and calculating the mean value of each real-time depth value of each pixel point forming each eye sub-region to be used as the reference depth value of the eye sub-region;

the pterygium identification device is respectively connected with the point-by-point inspection device and the region segmentation device and is used for sending out pterygium identification signals when a certain eye sub-region exists and the reference depth of field value of the certain eye sub-region is larger than the amplitude of the whole depth of field value and exceeds the limit, and outputting the relative position of the existing eye sub-region in the eye sub-image as a pterygium existing position;

and marking the relative position of the existing eye subarea region in the eye subimage by adopting a mode of an abscissa and an ordinate.

The eye pterygium detection positioning system is ingenious in design and convenient to operate. Because the auxiliary function of the detection and positioning of the pterygium of the eyes is added on the slit lamp hardware platform, the limited hardware resources are saved, and the real-time performance and the reliability of diagnosis of the pterygium of the eyes are improved.

Drawings

Embodiments of the invention will now be described with reference to the accompanying drawings, in which:

fig. 1 is a diagram illustrating an application scenario of the pterygium detection and localization system of the present invention.

Fig. 2 is a block diagram showing the configuration of a pterygium detection and localization system according to a first embodiment of the present invention.

Fig. 3 is a block diagram showing the configuration of a pterygium detection and localization system according to a second embodiment of the present invention.

Detailed Description

Embodiments of the pterygium detecting and positioning system of the eye according to the present invention will be described in detail below with reference to the drawings.

Slit lamps are an important instrument essential for ophthalmic examinations. The slit lamp consists of an illumination system and a binocular microscope, can not only enable superficial lesions to be observed clearly, but also adjust the focus and the width of a light source to be made into an optical section, so that deep tissue lesions can be also displayed clearly.

Slit lamps are known by the name of light that illuminates the eye through a slit. The light source is a narrow slit light source, so the light source is called as a 'smooth knife'. The 'optical knife' is irradiated on the eyes to form an optical section, so that the health condition of each part of the eyes can be observed. The principle is that the Tdahr phenomenon of the British physics of Medindall is utilized. The tyndall phenomenon is: when a light beam penetrates the gel, a bright "path" in the gel can be observed from the perpendicular direction of the incident light, which is called the tyndall phenomenon, also called the tyndall effect.

The construction of a slit lamp is mainly composed of two parts, namely a "slit lamp" and a "microscope". In order to facilitate the slit light source to illuminate various parts of the eye from different angles and the microscope to observe the eye from different angles, the slit lamp and the microscope are required to have enough left and right swinging angles mechanically. The slit edge of the light source of the slit lamp needs to be very flat, the slit needs to be clearly imaged on a circle center vertical plane swinging left and right, and the focus of the microscope also needs to be focused on the circle center vertical plane.

Slit lamps are currently available for detecting pupillary sphincter muscle, internal iris bleeding, blood vessels in the iris, and for detecting very subtle opacities on the cornea such as blisters, perforations, scars, and the like. However, the detection requires manual judgment and positioning, and a targeted pterygium detection and positioning mechanism in the slit lamp is lacked, and the pterygium is one of the common eye diseases.

In order to overcome the defects, the invention builds the pterygium detection and positioning system and can effectively solve the corresponding technical problems.

As shown in fig. 1, a diagram of an application scenario of the pterygium detection and localization system of the present invention is shown.

In fig. 1, the pterygium of the eye is present below the eye of the human body, falling within the examination range of the slit lamp.

Subsequently, the technical contents of the present invention will be described in detail from different points of view using one or more embodiments.

< first embodiment >

Fig. 2 is a block diagram showing the configuration of a pterygium detection and localization system according to a first embodiment of the present invention, the system including:

the miniature camera shooting equipment is positioned at the front end of the slit lamp and used for executing camera shooting operation on the environment of the eyes of the human body under the irradiation of the light source of the slit lamp when the slit lamp inspects the eyes of the human body so as to obtain a current eye image;

a superimposition display device embedded in a housing of the slit lamp, for receiving the eye sub-image and the eye portion area where the pterygium exists, and performing highlight red display of the eye portion area based on a relative position of the eye portion area where the pterygium exists in the eye sub-image while displaying the eye sub-image;

the signal filtering equipment is positioned inside the slit lamp, is connected with the miniature camera equipment and is used for executing maximum value filtering processing on the received current eye image so as to obtain a corresponding maximum value filtering image;

the eye segmentation equipment is connected with the signal filtering equipment and used for receiving the maximum value filtering image, and matching and segmenting the eye sub-image corresponding to the eye target from the maximum value filtering image based on the eye appearance characteristic;

the point-by-point detection equipment is connected with the eye segmentation equipment and is used for carrying out depth of field analysis on each pixel point in the eye sub-image so as to obtain a real-time depth of field value of each pixel point and calculating the mean value of the real-time depth of field values of the pixel points forming the eye sub-image to be used as the integral depth of field value of the eye sub-image;

the region segmentation equipment is positioned inside the slit lamp, is connected with the point-by-point inspection equipment, and is used for uniformly segmenting the eye sub-images to obtain each eye sub-region and calculating the mean value of each real-time depth value of each pixel point forming each eye sub-region to be used as the reference depth value of the eye sub-region;

the pterygium identification device is respectively connected with the point-by-point inspection device and the region segmentation device and is used for sending out pterygium identification signals when a certain eye sub-region exists and the reference depth of field value of the certain eye sub-region is larger than the amplitude of the whole depth of field value and exceeds the limit, and outputting the relative position of the existing eye sub-region in the eye sub-image as a pterygium existing position;

and marking the relative position of the existing eye subarea region in the eye subimage by adopting a mode of an abscissa and an ordinate.

< second embodiment >

Fig. 3 is a block diagram showing a configuration of a pterygium detection and localization system according to a second embodiment of the present invention, the system including:

the power detection device is positioned in the slit lamp and used for detecting the current irradiation power of a slit lamp light source and outputting the current irradiation power;

the parameter adjusting equipment is positioned in the slit lamp, is connected with the power detecting equipment and is used for performing size adjustment on the current irradiation power of the light source of the slit lamp under manual adjustment;

the miniature camera shooting equipment is positioned at the front end of the slit lamp and used for executing camera shooting operation on the environment of the eyes of the human body under the irradiation of the light source of the slit lamp when the slit lamp inspects the eyes of the human body so as to obtain a current eye image;

a superimposition display device embedded in a housing of the slit lamp, for receiving the eye sub-image and the eye portion area where the pterygium exists, and performing highlight red display of the eye portion area based on a relative position of the eye portion area where the pterygium exists in the eye sub-image while displaying the eye sub-image;

the signal filtering equipment is positioned inside the slit lamp, is connected with the miniature camera equipment and is used for executing maximum value filtering processing on the received current eye image so as to obtain a corresponding maximum value filtering image;

the eye segmentation equipment is connected with the signal filtering equipment and used for receiving the maximum value filtering image, and matching and segmenting the eye sub-image corresponding to the eye target from the maximum value filtering image based on the eye appearance characteristic;

the point-by-point detection equipment is connected with the eye segmentation equipment and is used for carrying out depth of field analysis on each pixel point in the eye sub-image so as to obtain a real-time depth of field value of each pixel point and calculating the mean value of the real-time depth of field values of the pixel points forming the eye sub-image to be used as the integral depth of field value of the eye sub-image;

the region segmentation equipment is positioned inside the slit lamp, is connected with the point-by-point inspection equipment, and is used for uniformly segmenting the eye sub-images to obtain each eye sub-region and calculating the mean value of each real-time depth value of each pixel point forming each eye sub-region to be used as the reference depth value of the eye sub-region;

the pterygium identification device is respectively connected with the point-by-point inspection device and the region segmentation device and is used for sending out pterygium identification signals when a certain eye sub-region exists and the reference depth of field value of the certain eye sub-region is larger than the amplitude of the whole depth of field value and exceeds the limit, and outputting the relative position of the existing eye sub-region in the eye sub-image as a pterygium existing position;

and marking the relative position of the existing eye subarea region in the eye subimage by adopting a mode of an abscissa and an ordinate.

Next, a detailed description will be given of the pterygium detection and localization system according to each of the above embodiments of the present invention.

The eye pterygium detection positioning system may further include: the wireless router is respectively in wireless communication connection with the point-by-point detection equipment and the region segmentation equipment through a wireless communication network; the point-by-point detection device and the area segmentation device are respectively realized by ASIC chips with different models, and are integrated on the same printed circuit board.

The eye pterygium detection positioning system may further include: the temperature sensing equipment is respectively connected with the point-by-point detection equipment and the zone segmentation equipment and is used for respectively detecting the shell temperatures of the point-by-point detection equipment and the zone segmentation equipment; the flash lamp controller is positioned on one side of the miniature camera equipment and is used for controlling the on-off of the flash lamp based on the real-time environment brightness; wherein controlling the flash to turn on and off based on the real-time ambient brightness comprises: and when the real-time environment brightness is less than or equal to the preset brightness threshold value, the flash lamp is turned on.

In the eye pterygium detection positioning system: the flash controller controlling the flash to be turned on and off based on the real-time ambient brightness includes: and when the real-time environment brightness is greater than the preset brightness threshold value, the flash lamp is turned off.

In the eye pterygium detection positioning system: the flash controller controlling the flash to be turned on and off based on the real-time ambient brightness includes: and when the real-time environment brightness is less than or equal to the preset brightness threshold, turning on the flash lamp and adjusting the flash brightness of the flash lamp according to the real-time environment brightness, wherein the lower the real-time environment brightness is, the higher the flash brightness of the flash lamp is.

In the eye pterygium detection positioning system: the eye segmentation device is internally provided with a storage unit used for storing input data and output data of the eye segmentation device.

In the eye pterygium detection positioning system: the point-by-point detection equipment is connected with the IIC control bus and used for receiving various control instructions sent by the IIC control bus.

In the eye pterygium detection positioning system: the eye segmentation device is further connected with a clock generator for receiving timing signals customized by the clock generator for the eye segmentation device.

In the eye pterygium detection positioning system: the point-by-point detection device is implemented by an ASIC chip, and the ASIC chip comprises an online programming interface.

In the eye pterygium detection positioning system: the eye segmentation device and the point-by-point detection device are located on the same printed circuit board and share the same circuit supply device.

In addition, the following detection modes are common in the human eyes by the slit lamp:

1. when a diffusion illumination method is used, the cornea, the iris and the crystal can be comprehensively observed by using the integrated light and low-power amplification;

2. when a direct focal illumination method is used, the curvature and thickness of the cornea, the existence of foreign matters and corneal posterior sediments (KP), and the gradation and the form of pathological changes such as infiltration, ulcer and the like can be observed; when the focus is pushed backwards, the turbid part of the crystal and the pathological condition of the front 1/3 of the vitreous body can be observed; if conical light is used, floating particles in the aqueous humor can be detected;

3. when using the mirror reflection irradiation method, the subtle changes of the front and back corneal pockets and the front and back crystalline pockets, such as the desquamated cells on the tear film, the patterns of the corneal endothelium, the front and back crystalline pockets and the patterns on the adult nucleus can be carefully observed;

4. when retro-reflection irradiation is used, corneal epithelial or endothelial edema, corneal post-corneal deposits, neovascularization, slight scars, and lens vacuoles, etc. can be found;

5. when the corneoscleral limbus spectroscopic illumination method is used, very slight clouding on the cornea such as blisters, perforations, scars, etc. can be found;

6. when using indirect illumination, the pupillary sphincter muscle, intra-iris bleeding, iris blood vessels, etc. can be observed. Meanwhile, the slit-lamp microscope can be additionally provided with a front lens, a contact lens, a three-face mirror and the like, and can be used for examining the peripheral part of the retina, the anterior chamber angle and the rear vitreous body in a matching way, so that stereoscopic vision can be generated through binocular observation.

Finally, it should be noted that each functional device in the embodiments of the present invention may be integrated into one processing device, or each device may exist alone physically, or two or more devices may be integrated into one device.

The functions, if implemented in the form of software-enabled devices and sold or used as a stand-alone product, may be stored in a computer-readable storage medium. Based on such understanding, the technical solution of the present invention may be embodied in the form of a software product, which is stored in a storage medium and includes instructions for causing a computer device (which may be a personal computer, a server, or a network device) to execute all or part of the steps of the method according to the embodiments of the present invention. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk or an optical disk, and other various media capable of storing program codes.

The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.