阅读说明：本技术 一种治疗奶牛***炎的中药组合物及其制备方法 (Traditional Chinese medicine composition for treating cow mastitis and preparation method thereof ) 是由 陈琳 邹金峰 滕钟秀 于 2020-07-10 设计创作，主要内容包括：本发明提供了一种治疗奶牛乳房炎的中药组合物,由下述重量份的原料制成：瓜蒌60-80份,夏枯草30-40份,柴胡30-45份,黄芩30-40份,连翘20-30份,青皮20-30份,当归20-30份,赤芍30-40份,急性子20-30份,王不留行20-30份,甘草10-20份。本发明治疗奶牛乳房炎的中药组合物具有副作用小、无残留、无耐药、绿色环保等优点,治疗奶牛乳房炎有效率可以达到95.5％,相比传统抗生素治疗具有很大优势,适合广泛推广和应用。(The invention provides a traditional Chinese medicine composition for treating cow mastitis, which is prepared from the following raw materials in parts by weight: 60-80 parts of snakegourd fruit, 30-40 parts of selfheal, 30-45 parts of radix bupleuri, 30-40 parts of scutellaria baicalensis, 20-30 parts of fructus forsythiae, 20-30 parts of pericarpium citri reticulatae viride, 20-30 parts of angelica sinensis, 30-40 parts of red paeony root, 20-30 parts of garden balsam seed, 20-30 parts of cowherb seed and 10-20 parts of liquorice. The traditional Chinese medicine composition for treating the cow mastitis has the advantages of small side effect, no residue, no drug resistance, environmental protection and the like, the effective rate of treating the cow mastitis can reach 95.5%, and compared with the traditional antibiotic treatment, the traditional Chinese medicine composition has great advantages and is suitable for wide popularization and application.)

1. A traditional Chinese medicine composition for treating cow mastitis is characterized by being prepared from the following raw materials in parts by weight: 60-80 parts of snakegourd fruit, 30-40 parts of selfheal, 30-45 parts of radix bupleuri, 30-40 parts of scutellaria baicalensis, 20-30 parts of fructus forsythiae, 20-30 parts of pericarpium citri reticulatae viride, 20-30 parts of angelica sinensis, 30-40 parts of red paeony root, 20-30 parts of garden balsam seed, 20-30 parts of cowherb seed and 10-20 parts of liquorice.

2. A preparation method of a traditional Chinese medicine composition for treating cow mastitis is characterized by comprising the following steps:

(1) weighing the raw materials according to the traditional Chinese medicine composition for treating cow mastitis in claim 1;

(2) putting the raw materials into a traditional Chinese medicine extraction tank, adding water, heating to boil, and performing reflux extraction to obtain an extract I;

(3) adding water into the traditional Chinese medicine extraction tank again, heating to boil, and performing reflux extraction to obtain an extract II;

(4) and mixing the two extracting solutions, filtering, concentrating the filtrate, and cooling to room temperature to obtain the traditional Chinese medicine composition for treating the mastitis of the dairy cow.

3. The preparation method of the traditional Chinese medicine composition for treating cow mastitis according to claim 2, wherein in the step (2), the water addition amount is 8-10 times of the total mass of the raw materials.

4. The preparation method of the Chinese medicinal composition for treating cow mastitis according to claim 2, wherein in the step (2), water is added, the mixture is heated to boiling, and then the reflux extraction is performed for 1 to 3 hours.

5. The preparation method of the traditional Chinese medicine composition for treating cow mastitis according to claim 2, wherein in the step (3), the water addition amount is 6-8 times of the total mass of the raw materials.

6. The preparation method of the Chinese medicinal composition for treating cow mastitis according to claim 2, wherein in the step (3), water is added, the decoction is carried out until the decoction is boiled, and the reflux extraction is carried out for 1 to 3 hours.

7. The preparation method of the traditional Chinese medicine composition for treating cow mastitis according to claim 2, wherein in the step (4), the concentration temperature of the filtrate is 65-75 ℃, and the vacuum degree is 0.06 MPa.

8. The method for preparing a Chinese medicinal composition for treating bovine mastitis according to claim 2, wherein in the step (4), the filtrate is concentrated to a relative density of 1.1 to 1.2 with respect to water.

Technical Field

The invention belongs to the technical field of veterinary medicines, and particularly relates to a traditional Chinese medicine composition for treating cow mastitis and a preparation method thereof.

Background

With the continuous improvement of the living standard of people, the milk becomes a necessary drink in the daily life of people at present, which also promotes the great development of the dairy cow breeding industry in China, however, the prevalence of dairy cow diseases restricts the development of the dairy industry to a certain extent, and the most serious is the mastitis of dairy cows. The symptoms of cow mastitis are parenchymal and interstitial inflammations of breasts, are common diseases in the cow industry, are clinically infected by pathogenic microorganisms such as escherichia coli, staphylococcus aureus, streptococcus agalactiae and the like, and are also important reasons for causing the cow mastitis due to improper application of trauma and milking techniques. The milk yield and the milk quality of the dairy cows after mastitis occurs are obviously reduced, and the treatment cost, the elimination rate and the death rate are increased, so that huge losses are caused to the dairy cow breeding industry.

At present, no effective anti-inflammatory medicine exists, the traditional treatment mostly takes antibiotics as main materials, although a certain treatment effect can be achieved, the treatment period of the antibiotics is long, medicine residues exist in milk, and bacteria are easy to generate drug resistance after the antibiotics are used for a long time, so that the treatment with the antibiotics has great defects.

Therefore, the research and development of a traditional Chinese medicine composition for treating cow mastitis and a preparation method thereof, which have the advantages of small side effect, no residue, no drug resistance and environmental protection, are technical problems to be solved urgently by the technical personnel in the field.

Disclosure of Invention

In view of the above, the invention provides a traditional Chinese medicine composition for treating cow mastitis and a preparation method thereof.

In order to achieve the purpose, the invention adopts the following technical scheme:

a traditional Chinese medicine composition for treating cow mastitis is prepared from the following raw materials in parts by weight: 60-80 parts of snakegourd fruit, 30-40 parts of selfheal, 30-45 parts of radix bupleuri, 30-40 parts of scutellaria baicalensis, 20-30 parts of fructus forsythiae, 20-30 parts of pericarpium citri reticulatae viride, 20-30 parts of angelica sinensis, 30-40 parts of red paeony root, 20-30 parts of garden balsam seed, 20-30 parts of cowherb seed and 10-20 parts of liquorice.

The invention mechanism of the invention is: according to the traditional Chinese medicine, the mastitis of the dairy cattle belongs to acute mastitis, is inflammation caused by phlegm, dampness, qi and blood stagnation without dispersing, and suppuration and carbuncle formation are caused by meat rot due to excessive heat. The therapeutic principle should be mainly to clear heat and remove toxicity, and the auxiliary should be to soothe liver, promote qi circulation, activate blood, remove stasis, eliminate swelling and eliminate hard mass. In the formula, the snakegourd fruit, the baical skullcap root and the weeping forsythia have the effects of clearing heat and removing toxicity and are used as monarch drugs, the Chinese thorowax root and the immature tangerine peel have the effects of soothing the liver and promoting the circulation of qi, the Chinese angelica and the red paeony root have the effects of activating blood and removing stasis and are used as ministerial drugs, the common selfheal fruit-spike, the garden balsam seed and the cowherb seed have. Wherein:

and (3) snakegourd fruit: sweet, slightly bitter and cold in taste; it enters lung, stomach and large intestine meridians; clearing heat and eliminating phlegm, relieving chest stuffiness and dissipating stagnation, moistening dryness and lubricating intestines, and is used for treating cough due to lung heat, turbid phlegm, yellow and thick phlegm, chest stuffiness and pain, chest stuffiness and fullness, acute mastitis, pulmonary abscess, intestinal abscess swelling and pain, and constipation.

Selfheal: pungent, bitter and cold in nature; it enters liver and gallbladder meridians; clearing liver-fire, improving eyesight, resolving hard mass and relieving swelling; can be used for treating conjunctival congestion, swelling and pain, eye bead nyctalgia, headache, giddiness, scrofula, goiter, mammary abscess, mammary nodules, and breast pain.

Bupleurum root: pungent and bitter in flavor and slightly cold in nature; entering liver, gallbladder and lung meridians; harmonizing exterior and interior, soothing liver-qi stagnation, lifting yang and sinking, allaying fever and checking malaria; can be used for treating common cold, fever, alternating chills and fever, distending pain in chest and hypochondrium, menoxenia, uterine prolapse, and proctoptosis.

Scutellaria baicalensis: bitter taste and cold nature; it enters lung, gallbladder, spleen, large intestine and small intestine meridians; clearing heat and drying dampness, purging fire and removing toxicity, stopping bleeding and preventing miscarriage; can be used for treating damp-warm syndrome, summer-heat dampness, chest distress, emesis, dampness and heat distention, dysentery, jaundice, cough due to lung heat, hyperpyrexia, polydipsia, hematemesis, carbuncle, swelling, sore, and threatened abortion.

Fructus forsythiae: bitter and cool; entering heart, liver and gallbladder meridians; clearing away heat and toxic materials, dispersing pathogenic accumulation, and relieving swelling; it is indicated for warm heat, erysipelas, macula, superficial infection, abscess, swelling, scrofula and stranguria.

Green tangerine peel: bitter and pungent taste, warm in nature; entering liver, gallbladder and stomach meridians; has effects of dispersing stagnated liver qi, relieving qi stagnation, and resolving food stagnation; can be used for treating distending pain in chest and hypochondrium, hernia pain, nodules of breast, mammary abscess, food stagnation, qi stagnation, and abdominal pain.

Chinese angelica: sweet, pungent and warm; it enters liver, heart and spleen meridians; enriching blood, promoting blood circulation, regulating menstruation, relieving pain, moistening dryness, lubricating intestines, treating various symptoms of blood deficiency, irregular menstruation and amenorrhea; dysmenorrhea, abdominal mass, metrorrhagia, abdominal pain due to cold deficiency, flaccidity, numbness of skin, intestinal dryness, constipation, dysentery, carbuncle, ulcer, traumatic injury.

Red peony root: bitter taste and slightly cold nature; entering liver meridian; clearing heat and cooling blood, and removing blood stasis and relieving pain; can be used for treating heat entering nutrient-blood, toxic heat macula, hematemesis and epistaxis, conjunctival congestion, swelling and pain, liver depression, hypochondriac pain, amenorrhea, dysmenorrhea, abdominal pain, traumatic injury, carbuncle, swelling, and pyocutaneous disease.

Acute seed: slightly bitter, pungent and warm in nature; has little toxicity; meridian tropism enters lung and liver meridians; break blood and soften hardness, remove food stagnation. Can be used for treating abdominal mass, amenorrhea, and dysphagia.

Seed of cowherb: bitter in nature and mild in taste; entering liver and stomach meridians; promoting blood circulation, dredging channels, promoting lactation, relieving swelling, promoting urination, and treating stranguria; can be used for treating amenorrhea, dysmenorrhea, galactorrhea, acute mastitis, and stranguria with pain.

Licorice root: sweet in taste and neutral in nature; the heart meridian, the lung meridian, the spleen meridian and the stomach meridian; replenishing qi, strengthening the middle warmer, clearing away heat and toxic materials, expelling phlegm, relieving cough, relieving spasm and pain, and regulating drug properties; it can be used for treating spleen qi deficiency, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limbs spasm, pain, toxic heat, pyocutaneous disease, sore throat, and drug and food poisoning; relieve the toxicity and the severity of the drugs.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating cow mastitis, which comprises the following steps:

(1) weighing the raw materials according to the traditional Chinese medicine composition for treating the cow mastitis;

(2) putting the raw materials into a traditional Chinese medicine extraction tank, adding water, heating to boil, and performing reflux extraction to obtain an extract I;

(3) adding water into the traditional Chinese medicine extraction tank again, heating to boil, and performing reflux extraction to obtain an extract II;

(4) and mixing the two extracting solutions, filtering, concentrating the filtrate, and cooling to room temperature to obtain the traditional Chinese medicine composition for treating the mastitis of the dairy cow.

Further, in the step (2), the water adding amount is 8-10 times of the total mass of the raw materials.

Further, in the step (2), water is added, the mixture is heated to boiling, and then the reflux extraction is carried out for 1 to 3 hours.

Further, in the step (3), the water adding amount is 6-8 times of the total mass of the raw materials.

Further, in the step (3), water is added, the decoction is carried out until the decoction is boiled, and the reflux extraction is carried out for 1 to 3 hours.

Further, in the step (4), the concentration temperature of the filtrate is 65-75 ℃, and the vacuum degree is 0.06 MPa.

Further, in the above step (4), the filtrate is concentrated to a relative density of 1.1 to 1.2 with respect to water.

The invention has the beneficial effects that: the traditional Chinese medicine composition for treating the cow mastitis has the advantages of small side effect, no residue, no drug resistance, environmental protection and the like, the effective rate of treating the cow mastitis can reach 95.5%, and compared with the traditional antibiotic treatment, the traditional Chinese medicine composition has great advantages and is suitable for wide popularization and application.

Detailed Description

The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.