阅读说明：本技术 缓冲离心机震动分子生物学实验平台 (Buffering centrifuge vibration molecular biology experiment platform ) 是由 张时良 周珊峡 刘君 柳又祎 于 2021-09-03 设计创作，主要内容包括：本发明公开了缓冲离心机震动分子生物学实验平台,包括实验平台本体,安装于地面上,实验平台本体上设置有离心机本体,并在离心机本体上设置有用于检验振动频率的振动传感器,实验平台本体上设置有用于感应离心机本体工作状态的红外线感应器；缓冲组件,设置于实验平台本体上,离心机本体上设置有放置框,缓冲组件通过输送配重块至放置框上以用于降低离心机本体的振动速率；升降组件,设置于实验平台本体内部,实验平台本体上设置有试剂架组,升降组件用于根据离心机本体的开停机来控制试剂架组的运动状况,此缓冲离心机震动分子生物学实验平台,通过缓冲组件使得配重块增加离心机本体的重量,且升降组件使得试剂架组避免受到热量的影响。(The invention discloses a molecular biology experiment platform for buffering the vibration of a centrifugal machine, which comprises an experiment platform body, wherein the experiment platform body is arranged on the ground, the experiment platform body is provided with the centrifugal machine body, a vibration sensor for detecting the vibration frequency is arranged on the centrifugal machine body, and an infrared sensor for sensing the working state of the centrifugal machine body is arranged on the experiment platform body; the buffering component is arranged on the experiment platform body, a placing frame is arranged on the centrifuge body, and the buffering component is used for reducing the vibration rate of the centrifuge body by conveying a balancing weight to the placing frame; the lifting assembly is arranged inside the experiment platform body, the reagent rack group is arranged on the experiment platform body, the lifting assembly is used for controlling the motion situation of the reagent rack group according to the starting and stopping of the centrifuge body, the buffering centrifuge shakes the molecular biology experiment platform, the balancing weight is increased by the buffering assembly, and the lifting assembly enables the reagent rack group to avoid being influenced by heat.)

1. Buffering centrifuge vibrations molecular biology experiment platform, its characterized in that: the method comprises the following steps:

the experiment platform comprises an experiment platform body (1) which is arranged on the ground, wherein a centrifuge body (2) is arranged on the experiment platform body (1), a vibration sensor (3) for detecting vibration frequency is arranged on the centrifuge body (2), and an infrared sensor (4) for sensing the working state of the centrifuge body (2) is arranged on the experiment platform body (1);

the buffer component (5) is arranged on the experiment platform body (1), a placing frame (6) is arranged on the centrifuge body (2), and the buffer component (5) conveys the balancing weight to the placing frame (6) to reduce the vibration rate of the centrifuge body (2);

the reagent shelf moving device comprises a lifting assembly (7) arranged inside an experiment platform body (1), wherein a reagent shelf group (8) is arranged on the experiment platform body (1), and the lifting assembly (7) is used for controlling the moving condition of the reagent shelf group (8) according to the starting and stopping of a centrifuge body (2).

2. The buffered centrifuge shock molecular biology experimental platform of claim 1, wherein: the buffer component (5) comprises fixed frames (51) symmetrically arranged on the experiment platform body (1), a first motor (52) is arranged in the experiment platform body (1), a chain wheel set (53) is arranged in the fixed frame (51), one of the chain wheel sets (53) is connected with the output end of the first motor (52), a fixed seat (54) is arranged in the experiment platform body (1), and the other chain wheel set (53) is connected with the fixed seat (54) through a transmission column (55), a rotating column (56) used for being connected with the inner wall of the fixed frame (51) is arranged on the chain wheel set (53), the output end of the first motor (52) is connected with the transmission post (55) through a belt pulley (57), so that the first motor (52) drives the parallel chain wheel sets (53) to synchronously rotate through the belt pulley (57).

3. The buffered centrifuge shock molecular biology experimental platform of claim 2, wherein: an input frame (58) and an output frame (59) for conveying balancing weights are respectively arranged on two sides of the fixing frame (51), conveying columns (591) are arranged inside the input frame (58) and the output frame (59), a connecting column (592) is arranged on the chain wheel set (53), a sliding block (593) is arranged on the connecting column (592), supporting columns (594) which are used for being in a staggered state with the conveying columns (591) are arranged on the sliding block (593), and a limiting part (50) for limiting the movement of the sliding block (593) is arranged inside the fixing frame (51);

the first motor (52) enables a sliding block (593) to perform directional movement under the action of a limiting piece (50) through a chain wheel set (53), the sliding block (593) moves to the bottom of an input frame (58) and continues to perform upward movement, and a supporting column (594) on the sliding block (593) drives a balancing weight to move above an output frame (59), so that a conveying column (591) in the output frame (59) blocks the balancing weight to enable the balancing weight to slide into a placement frame (6) along the output frame (59).

4. The buffered centrifuge shock molecular biology experimental platform of claim 3, wherein: the limiting part (50) comprises a limiting frame (501) arranged inside a fixing frame (51), the limiting frame (501) is connected with a sliding block (593) in a sliding mode, and a guide column (502) used for being connected with the inner wall of the fixing frame (51) is arranged on the limiting frame (501), so that the sliding block (593) can conduct directional movement under the action of the limiting frame (501).

5. The buffered centrifuge shock molecular biology experimental platform of claim 3, wherein: the cavity of input frame (58) and output frame (59) inside all sets up and is the rhombus, and input frame (58) and output frame (59) one end of fixing frame (51) inside are provided with baffle (595) that are used for preventing the balancing weight and drop.

6. The buffered centrifuge shock molecular biology experimental platform of claim 1, wherein: lifting unit (7) is including setting up in inside second motor (71) of experiment platform body (1), and be provided with sleeve (72) on second motor (71) output, just sleeve (72) inside is provided with threaded rod (73), be provided with on threaded rod (73) and be used for driving reagent frame group (8) and carry out directional motion's driving piece (74), infrared inductor (4) send signal to second motor (71) department and make it operate, so that second motor (71) make threaded rod (73) drive driving piece (74) move through sleeve (72).

7. The buffered centrifuge shock molecular biology experimental platform of claim 6, wherein: the driving piece (74) comprises a driving block (741) arranged on the threaded rod (73), a limiting slide rail (742) which is connected with the driving block (741) in a sliding mode is arranged inside the experiment platform body (1), and a supporting frame (743) which is connected with the driving block (741) is arranged at the bottom of the reagent frame group (8), so that the driving block (741) drives the reagent frame group (8) to perform synchronous lifting action through the supporting frame (743).

8. The buffered centrifuge shock molecular biology experimental platform of claim 2, wherein: place between frame (6) and centrifuge body (2) to be connected with it through bolt (9), just it sets up adult font to place frame (6) inner wall, so that the balancing weight of output frame (59) inside is along placing frame (6) inner wall evenly distributed inside it.

Technical Field

The invention relates to the technical field of centrifuge experiment platforms, in particular to a molecular biology experiment platform for buffering the vibration of a centrifuge.

Background

Molecular biology studies the structure and function of biological macromolecules from the molecular level to elucidate the science of the nature of life phenomena. Since the 50 s of the 20 th century, molecular biology was the leading edge and growth point of biology, and its major research fields include protein systems, protein-nucleic acid systems, and protein-lipid systems. In 1953, Watson and Crick propose a double helix structure model of DNA molecules as a sign of birth of molecular biology.

In the molecular biology experiment process, a centrifuge is often used to accelerate the separation of molecular structures in a reagent, and the centrifuge is an instrument often used in the biology experiment and generates centrifugal force by means of high-speed rotation of a rotating shaft so as to separate substances with different densities and sizes. Can achieve the purpose of primary separation and purification, and is an indispensable instrument in a laboratory. The rotational speed can be divided into three types, namely low speed (<8000rpm), high speed (8000-. The centrifugal machine can be divided into a table type centrifugal machine and a floor type centrifugal machine according to the volume and the placing position. The desktop centrifuge has a small volume, is usually a medium-low speed centrifuge and is commonly used for general molecular biology experiments; the floor type centrifuge has a large volume, is often provided with a temperature reduction and control device, is mostly a high-speed centrifuge, is commonly used for preparation, preliminary separation and large-scale centrifugation, and is used for centrifugation at certain required temperature; most of centrifuges of the existing molecular biology experiment platform are directly arranged on an experiment table plate, and in the experiment process, the phenomenon that the specific gravity of an original sample is not equal to that of the balancing liquid in the sample loading process of the centrifugal tube often occurs, so that the vibration phenomenon occurs in the use process of the centrifugal machine, wherein slight vibrations do not affect the normal operation of the centrifuge, but when the vibration speed Fr > 25mm/s, the centrifuge needs to be shut down, and during the experiment, various reagent centrifuges are needed, because the kind of reagent is different, and then the condition such as time, the temperature of centrifugation is all different, and centrifuge itself can produce a large amount of heats at high-speed operation in-process, and the produced heat gives off to in the surrounding environment mostly, and then causes the influence to the reagent that part needs to carry out the storage in low temperature environment. To this end, we propose a molecular biology experimental platform that buffers centrifuge vibration.

Disclosure of Invention

The invention aims to provide a molecular biology experiment platform for buffering the vibration of a centrifuge so as to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: the molecular biology experiment platform for buffering the vibration of the centrifugal machine comprises an experiment platform body, wherein the experiment platform body is arranged on the ground, a centrifugal machine body is arranged on the experiment platform body, a vibration sensor for detecting the vibration frequency is arranged on the centrifugal machine body, and an infrared sensor for sensing the working state of the centrifugal machine body is arranged on the experiment platform body; the buffer assembly is arranged on the experiment platform body, a placing frame is arranged on the centrifuge body, and the buffer assembly is used for reducing the vibration rate of the centrifuge body by conveying a balancing weight to the placing frame; the lifting assembly is arranged inside the experiment platform body, the reagent rack group is arranged on the experiment platform body, and the lifting assembly is used for controlling the motion condition of the reagent rack group according to the starting and stopping of the centrifuge body so as to reduce the vibration of the centrifuge body and avoid the interference of the reagent on the reagent rack group on the temperature under the action of the buffer assembly and the lifting assembly.

Preferably, the buffering subassembly sets up the fixed frame on the experiment platform body including the symmetry, just the inside first motor that is provided with of experiment platform body, and fixed frame inside is provided with chain wheelset, one of them the chain wheelset is connected with first motor output, and the inside fixing base that is provided with of experiment platform body, and another be connected with it through the transmission post between chain wheelset and the fixing base, and be provided with the rotary column that is used for going on being connected with fixed frame inner wall on the chain wheelset, be connected with it through the belt pulley between first motor output and the transmission post, so that first motor drives parallel arrangement's chain wheelset through the belt pulley and carries out synchronous rotation to it carries out synchronous motion to drive chain wheelset under the effect of belt pulley.

Preferably, an input frame and an output frame for conveying the balancing weight are respectively arranged on two sides of the fixing frame, conveying columns are arranged in the input frame and the output frame, connecting columns are arranged on the chain wheel sets, sliders are arranged on the connecting columns, supporting columns which are in a staggered state with the conveying columns are arranged on the sliders, and limiting parts for limiting the movement of the sliders are arranged in the fixing frame;

the first motor enables the sliding block to move directionally under the action of the limiting part through the chain wheel set, the sliding block moves to the bottom of the input frame and continues to move upwards, the supporting column on the sliding block drives the balancing weight to move to the upper portion of the output frame, so that the conveying column inside the output frame blocks the balancing weight to enable the balancing weight to slide down to the placement frame along the output frame, the balancing weight slides to the placement frame, gravity of the centrifuge body is increased, and vibration frequency of the centrifuge body is reduced.

Preferably, the locating part is including setting up in the inside spacing frame of fixed frame, just spacing frame carries out sliding connection with the slider, and be provided with on the spacing frame and be used for carrying out the guide post of being connected with fixed frame inner wall, so that the slider carries out directional motion under spacing frame's effect to make the slider carry out directional motion under spacing frame's effect.

Preferably, the cavity inside input frame and the output frame all sets up to be the rhombus, and the inside input frame of fixed frame and output frame one end are provided with the baffle that is used for preventing the balancing weight to drop to avoid the balancing weight to take place the landing phenomenon.

Preferably, the lifting unit is including setting up in the inside second motor of experiment platform body, and be provided with the sleeve on the second motor output, just the inside threaded rod that is provided with of sleeve, be provided with the driving piece that is used for driving reagent frame group and carries out directional motion on the threaded rod, infrared inductor sends signal to second motor department and makes it operate, so that the second motor makes the threaded rod drive the driving piece through the sleeve and moves to control the motion situation of reagent frame group under the effect of driving piece.

Preferably, the driving piece is including setting up the drive block on the threaded rod, experiment platform body inside is provided with and is used for carrying out sliding connection's spacing slide rail with the drive block, reagent frame group bottom is provided with and is used for carrying out the support frame of being connected with the drive block, so that the drive block drives reagent frame group through the support frame and carries out the action of going up and down in step, makes reagent frame carry out directional lift action through the drive block.

Preferably, the placing frame is connected with the centrifuge body through bolts, and the inner wall of the placing frame is arranged in a herringbone manner, so that the balancing weight inside the output frame is uniformly distributed inside the placing frame along the inner wall of the placing frame.

Compared with the prior art, the invention has the beneficial effects that:

1. according to the reagent rack group, the balancing weights are uniformly distributed in the placing frame through the buffer assembly, so that the buffer effect is achieved by increasing the weight of the centrifuge body, and meanwhile, the movement condition of the reagent rack group is controlled under the effect of the lifting assembly, so that the influence of heat emitted to the air to the reagents on the reagent rack group in the process of separating multiple groups of reagents by the centrifuge body is avoided.

2. The inner wall of the bottom of the placing frame is arranged in a herringbone shape, so that the balancing weight in the output frame slides to the middle part of the placing frame and slides to two sides, and the balancing weight is uniformly distributed in the placing frame.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic structural view of the present invention;

FIG. 3 is a schematic structural view of the experiment platform body taken away in the present invention;

FIG. 4 is a schematic view of a buffer assembly according to the present invention;

FIG. 5 is a schematic view of a position limiting member according to the present invention;

FIG. 6 is a partial schematic view of the present invention;

FIG. 7 is a side view of the placement frame structure of the present invention;

FIG. 8 is a schematic view of a lifting assembly according to the present invention.

In the figure: 1-experiment platform body; 2-centrifuge body; 3-a vibration sensor; 4-infrared sensor; 5-a buffer component; 6-placing a frame; 7-a lifting assembly; 8-reagent rack group; 9-bolt; 51-a fixed frame; 52-a first motor; 53-chain wheel set; 54-a fixed seat; 55-a drive column; 56-rotating columns; 57-a pulley; 58-input box; 59-output box; 50-a limit piece; 591-a transfer column; 592-connecting column; 593-a slide block; 594-support columns; 595-a baffle; 501-a limit frame; 502-a guide post; 71-a second motor; 72-a sleeve; 73-threaded rod; 74-a drive member; 741-a drive block; 742-limit slide; 743-support frame.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-8, the present invention provides a technical solution: the technical scheme solves the problem that the vibration phenomenon of the centrifuge body 2 occurs in the use process due to the fact that the specific gravity of an original sample is not equal to the specific gravity of a balancing liquid in the working process of the existing centrifuge body 2, and the generated heat is dissipated to the surrounding environment in the experiment process to influence part of reagents needing to be stored in a low-temperature environment, and the technical scheme is correspondingly improved aiming at the problem;

as shown in fig. 1:

the experimental platform comprises an experimental platform body 1 and a centrifuge body 2 which are arranged on the ground, an infrared sensor 4, a placing frame 6, a reagent frame group 8, a fixing frame 51 and an input frame 58, wherein the centrifuge body 2 is arranged on the experimental platform body 1 through the experimental platform body 1 arranged on the ground, and the infrared sensor 4 for sensing the working state of the centrifuge body 2 is arranged on the experimental platform body 1; the bottom of the centrifuge body 2 is provided with a placing frame 6, the inner wall of the placing frame 6 is arranged in a herringbone shape, and the reagent rack group 8 is arranged on the experiment platform body 2; fixed frame 51 symmetry is installed in centrifuge body 2 both sides, and input frame 58 sets up in fixed frame 51 one side to make and carry the balancing weight to placing in the frame 6 through input frame 58, thereby increase the weight of centrifuge body 2 and play buffering cushioning effect, infrared inductor 4 detects whether centrifuge body 2 is in operating condition simultaneously.

As shown in fig. 2:

including centrifuge body 2, place frame 6, lifting unit 7, reagent frame group 8, chain wheel group 53, input frame 58, second motor 71, spacing slide rail 742, the balancing weight is through input frame 58 landing to placing the weight of frame 6 in order to increase centrifuge body 2, wherein second motor 71 installs in 1 inner wall of experiment platform body, and spacing slide rail 742 installs in 1 inner wall of experiment platform body, and chain wheel group 53 sets up inside fixed frame 51, lifting unit 7 makes reagent frame group 8 carry out directional position adjustment.

As shown in fig. 3:

including vibration sensor 3, fixed frame 51, chain wheel group 53, belt pulley 57, input frame 58, output frame 59, guide post 502, vibration sensor 3 installs in centrifuge body 2 one side to the vibration sensor 3 that makes is used for examining centrifuge body 2's vibration frequency, and wherein output frame 59 installs in the one side of keeping away from input frame 58 of fixed frame 51, and guide post 502 installs in fixed frame 51 bottom and top inner wall.

As shown in fig. 4, 5, and 6:

the device comprises a buffer component 5 arranged on a fixed frame 51, a first motor 52, a chain wheel set 53, a fixed seat 54, a transmission column 55, a rotating column 56, a belt pulley 57, an input frame 58, an output frame 59, a limiting piece 50, a conveying column 591, a connecting column 592, a sliding block 593, a supporting column 594, a baffle 595, a limiting frame 501 and a guide column 502;

a first motor 52 is installed on the inner wall of the experiment platform body 1, chain wheel sets 53 are arranged in the fixing frame 51, one end of one chain wheel set 53 is connected with the output end of the first motor 52, a fixing seat 54 is installed on the inner wall of the top of the experiment platform body 1, and the other chain wheel set 53 is connected with the fixing seat 54 through a transmission column 55;

a rotating column 56 for connecting with the inner wall of the fixed frame 51 is connected to one end of the chain wheel set 53, which is far away from the first motor 52 and the transmission column 55, and the output end of the first motor 52 is connected with the transmission column 55 through a belt pulley 57, so that the first motor 52 drives the chain wheel set 53 to synchronously rotate through the belt pulley 57; an input frame 58 and an output frame 59 for conveying balancing weights are connected to two sides of the fixing frame 51 respectively, conveying columns 591 are installed inside the input frame 58 and the output frame 59, and cavities inside the input frame 58 and the output frame 59 are arranged in an oblique line shape;

the limiting part 50 used for limiting the movement of the sliding block 593 is arranged inside the fixed frame 51, the limiting part 50 is composed of a limiting frame 501 and guide posts 502, the limiting frame 501 is arranged inside the fixed frame 51, the limiting frame 501 is in sliding connection with the sliding block 593, and the guide posts 502 used for being connected with the bottom and the top inner walls of the fixed frame 51 are installed on the limiting frame 501, so that the sliding block 593 can perform directional movement under the action of the limiting frame 501, and the movement track of the sliding block 593 is the same as that of the chain wheel set 53.

As shown in fig. 7:

including centrifuge body 2, infrared inductor 4, place frame 6, bolt 9, infrared inductor 4 is the sensor that utilizes the physical property of infrared ray to carry out the measurement. Infrared light is also called infrared light, and has properties of reflection, refraction, scattering, interference, absorption and the like. Any substance, as long as it has a certain temperature itself (above absolute zero), can radiate infrared rays. Infrared inductor 4 does not contact with the testee direct contact when measuring, therefore does not have the friction to there are sensitivity height, advantages such as reaction are fast, and place frame 6 and set to set up adult's font, so that the balancing weight of messenger evenly slides to both sides, and place frame 6 and pass through bolt 9 to be fixed on centrifuge body 2.

As shown in fig. 8:

the device comprises a lifting component 7, a second motor 71, a sleeve 72, a threaded rod 73, a driving piece 74, a driving block 741, a limiting slide rail 742 and a support frame 743, wherein the lifting component 7 in the scheme comprises the second motor 71 installed inside an experiment platform body 1, the sleeve 72 is installed on the output end of the second motor 71, the threaded rod 73 is connected inside the sleeve 72, the driving piece 74 used for driving a reagent rack group 8 to do directional movement is arranged on the threaded rod 73, an infrared sensor 4 sends a signal to the second motor 71 to enable the second motor 71 to operate, so that the threaded rod 73 drives the driving piece 74 to move through the sleeve 72 by the second motor 71, the driving piece 74 in the scheme comprises a driving block 741 installed on the threaded rod 73, the limiting slide rail 742 used for being in sliding connection with the driving block 741 is installed on the inner wall of the experiment platform body 1, the support frame 743 used for being connected with the driving block 741 is installed at the bottom of the reagent rack group 8, so that the driving block 741 drives the reagent holder assembly 8 to synchronously lift and lower through the supporting frame 743.

The scheme reduces the vibration speed of the centrifuge body 2 under the action of the buffer component 5 and the lifting component 7, and avoids the influence of the heat generated in the working process of the centrifuge body 2 on the reagent rack group 8, before the centrifuge body 2 starts to work, the placing frame 6 is fixed on the centrifuge body 2 through the bolt 9, because the centrifuge body 2 generates slight vibration in the working process, the end cover of the centrifuge body 2 is closed, then the infrared sensor 4 sends a signal to the second motor 71, the second motor 71 is started to drive the threaded rod 73 to rotate through the sleeve 72, the driving block 741 drives the reagent rack group 8 to perform directional descending motion through the supporting frame 743 under the action of the limiting slide rail 742, so that the reagent rack group 8 is hidden inside the experiment platform body 1, and the influence of heat emitted by the centrifuge body 2 on the outside of the experiment platform body 1 is avoided;

when the vibration rate Fr of the centrifuge body 2 is larger than 25mm/s, the vibration sensor 3 sends a signal to the first motor 52, the output end of the first motor 52 drives one of the chain wheel sets 53 to rotate, the transmission column 55 is driven to synchronously rotate under the action of the belt pulley 57, and the other chain wheel set 53 is further driven to synchronously rotate, at this time, the slide block 593 connected with the chain wheel set 53 through the connecting column 592 performs directional track motion under the action of the limiting frame 501 and the guide column 502, the track of the slide block is the same as the motion track of the chain wheel set 53, because the cavities inside the input frame 58 and the output frame 59 and the conveying column 591 are both arranged in an oblique line shape, and further under the action of the baffle 595, the balancing weight blocks are blocked at the baffle 595, and in the process that the slide block 593 moves to the bottom of the input frame 58 and continues to move upwards, the supporting column 594 and the conveying column 591 in the scheme are in a staggered state, and then the support post 594 on the slide block 593 drives the balancing weight to move to the upper side of the output frame 59 along the track, when the balancing weight moves to the bottom of the output frame 59, the balancing weight at this time is blocked by the conveying post 591 inside the output frame 59, so that the balancing weight slides into the placing frame 6 along the output frame 59, the inner wall of the placing frame 6 is arranged in a herringbone shape, and further the balancing weight inside the output frame 59 is uniformly distributed inside the placing frame 6 along the inner wall of the placing frame 6, so that the weight of the centrifuge body 2 is increased, the buffering effect is achieved, and the damage to the structure inside the centrifuge body 2 caused by the overlarge vibration speed is avoided.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.