阅读说明：本技术 一种治疗蹄部疾病的药物及其制备方法和应用 (Medicine for treating hoof diseases and preparation method and application thereof ) 是由 张大为 于 2020-06-09 设计创作，主要内容包括：本发明适用于药物技术领域,提供了一种治疗蹄部疾病的药物及其制备方法和应用,该药物包括以下组分：氧化锌、松香、鞣酸、碘仿、丁香油、膨润土、硫酸铝。本发明提供的药物,通过上述组分的复配,可用于有效治疗由于细菌感染、外伤引起的疣性蹄炎、趾间蹄炎、蹄底溃烂、蹄漏、腐蹄病等蹄部疾病；将其涂抹于患病部位表面,可形成保护膜,从而达到患病部位与外界隔离,杜绝药物脱落及与水等污物接触,进而可达到祛腐、止血、生津、加快伤口愈合等目的,其具有治疗费用低、疗效高、不反弹、药物原料无抗生素添加、使用范围广等特点。(The invention is applicable to the technical field of medicaments, and provides a medicament for treating hoof diseases, a preparation method and application thereof, wherein the medicament comprises the following components: zinc oxide, rosin, tannic acid, iodoform, clove oil, bentonite and aluminum sulfate. The medicine provided by the invention can be used for effectively treating hoof diseases such as verrucous hoof inflammation, toe-to-toe hoof inflammation, hoof bottom ulceration, hoof leakage, foot rot and the like caused by bacterial infection and trauma through compounding the components; the medicine is smeared on the surface of a diseased part to form a protective film, so that the diseased part is isolated from the outside, the medicine is prevented from falling off and contacting with dirt such as water, the purposes of removing decay, stopping bleeding, promoting the secretion of saliva or body fluid, accelerating wound healing and the like can be achieved, and the medicine has the characteristics of low treatment cost, high curative effect, no rebound, no antibiotic addition in medicine raw materials, wide application range and the like.)

1. The medicine for treating hoof diseases is characterized by comprising the following components in parts by weight: 60-110 parts of zinc oxide, 80-130 parts of rosin, 1-10 parts of tannic acid, 1-10 parts of iodoform, 20-40 parts of clove oil, 30-70 parts of bentonite and 1-10 parts of aluminum sulfate.

2. The medicament for treating hoof diseases according to claim 1, wherein the medicament comprises the following components in parts by weight: 70-100 parts of zinc oxide, 90-120 parts of rosin, 3-7 parts of tannic acid, 3-7 parts of iodoform, 25-35 parts of clove oil, 40-60 parts of bentonite and 3-7 parts of aluminum sulfate.

3. The medicament for treating hoof diseases according to claim 2, wherein the medicament comprises the following components in parts by weight: 80-90 parts of zinc oxide, 100-110 parts of rosin, 4-6 parts of tannic acid, 4-6 parts of iodoform, 28-33 parts of clove oil, 45-55 parts of bentonite and 4-6 parts of aluminum sulfate.

4. A process for the preparation of a medicament according to any one of claims 1 to 3, comprising the steps of:

weighing zinc oxide, rosin, tannic acid, iodoform, clove oil, bentonite and aluminum sulfate according to the weight parts of the components for later use;

mixing zinc oxide, clove oil, iodoform, tannic acid, rosin, bentonite and aluminum sulfate in sequence to obtain the medicine.

5. A medicament obtainable by the process according to claim 4.

6. The medicament of claim 5, wherein the medicament is in the form of a paste.

7. Use of a medicament according to any one of claims 1 to 3 and 5 to 6 in the manufacture of a medicament for treating hoof diseases in an animal.

8. A use as claimed in claim 7, wherein said hoof disease comprises at least one of verrucous hoof inflammation, inter-digital hoof inflammation, hoof base ulceration, hoof leaks and foot rot.

9. A use as claimed in claim 7, wherein the animal is a bovine.

Technical Field

The invention belongs to the technical field of medicines, and particularly relates to a medicine for treating hoof diseases, and a preparation method and application thereof.

Background

Foot and leg diseases are the first four diseases in the dairy cattle and beef cattle industry, and the foot and leg diseases eliminate a large number of dairy cattle and beef cattle every year, thereby bringing huge loss to the animal husbandry production. Therefore, it is very necessary to treat the acropodopathy of cows and beef cattle.

However, at present, the traditional intramuscular injection of antibiotics and topical application to affected parts are still used for the treatment of hoof diseases in livestock. Wherein, intramuscular injection of antibiotics is easy to cause drug residue on dairy cattle; the traditional local medicine coating is difficult to prevent the affected part from being isolated from water and the outside, and the medicine is easy to fall off to achieve the treatment effect.

Therefore, there is a need to find a new drug for nonresistant therapy that can effectively treat hoof diseases of cows and beef cattle.

Disclosure of Invention

The embodiment of the invention aims to provide a medicament for treating hoof diseases, and aims to solve the problems in the background art.

The embodiment of the invention is realized in such a way that the medicine for treating hoof diseases comprises the following components in parts by weight: 60-110 parts of zinc oxide, 80-130 parts of rosin, 1-10 parts of tannic acid, 1-10 parts of iodoform, 20-40 parts of clove oil, 30-70 parts of bentonite and 1-10 parts of aluminum sulfate.

As another preferable scheme of the embodiment of the invention, the medicament comprises the following components in parts by weight: 70-100 parts of zinc oxide, 90-120 parts of rosin, 3-7 parts of tannic acid, 3-7 parts of iodoform, 25-35 parts of clove oil, 40-60 parts of bentonite and 3-7 parts of aluminum sulfate.

As another preferable scheme of the embodiment of the invention, the medicament comprises the following components in parts by weight: 80-90 parts of zinc oxide, 100-110 parts of rosin, 4-6 parts of tannic acid, 4-6 parts of iodoform, 28-33 parts of clove oil, 45-55 parts of bentonite and 4-6 parts of aluminum sulfate.

Another object of the embodiments of the present invention is to provide a method for preparing the above-mentioned medicament, which comprises the following steps:

weighing zinc oxide, rosin, tannic acid, iodoform, clove oil, bentonite and aluminum sulfate according to the weight parts of the components for later use;

mixing zinc oxide, clove oil, iodoform, tannic acid, rosin, bentonite and aluminum sulfate in sequence to obtain the medicine.

The embodiment of the invention also aims to provide a medicament prepared by the preparation method.

As another preferable mode of the embodiment of the present invention, the dosage form of the drug is an ointment.

It is another object of an embodiment of the present invention to provide a use of the above-mentioned medicament for the preparation of a medicament for treating hoof diseases in an animal.

As another preferred aspect of the embodiments of the present invention, the hoof disease includes at least one of wart-like hootis, toe-to-toe hootis, hoof base ulceration, hoof leaks, and foot rot.

As another preferred embodiment of the present invention, the animal is a bovine.

The pharmacological action of the medicine provided by the embodiment of the invention is as follows: the zinc oxide has the functions of removing the necrotic tissue, promoting granulation, protecting wound surfaces, promoting skin and wound healing, slightly sterilizing and astringing; the clove oil has the functions of sterilization, soothing and pain relieving; clove oil and zinc oxide are mixed to form clove oil cement which has the functions of water resistance and stimulation isolation, and meanwhile, the clove oil cement is compounded with rosin and has adhesiveness and toughness after being cured; the tannic acid can precipitate protein, and has hemostatic and astringent effects; aluminum sulfate and bentonite have hemostatic effect.

The medicine for treating the hoof diseases provided by the embodiment of the invention can be used for effectively treating the hoof diseases such as verrucous hootis, toe-to-toe hootis, hoof bottom ulceration, hoof leakage, foot rot and the like caused by bacterial infection and trauma through compounding of the components such as zinc oxide, clove oil, rosin, tannic acid and the like; the composition is applied to the surface of a diseased part to form a protective film, so that the diseased part is isolated from the outside, the medicine is prevented from falling off and contacting with dirt such as water, the purposes of removing decay, stopping bleeding, promoting the secretion of saliva or body fluid, accelerating wound healing and the like can be achieved, and the composition has the characteristics of low treatment cost, high curative effect, no rebound, no antibiotic addition (can be used for non-antibiotic treatment) of medicine raw materials, wide application range and the like.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.