Topical compositions
阅读说明:本技术 局部组合物 (Topical compositions ) 是由 马蒂尔德·德劳恩 克里斯蒂娜·门得洛克-埃丁格 于 2018-12-17 设计创作,主要内容包括:本发明涉及以特定比例包含泛醇、基于聚硅氧烷的紫外线滤光剂和微粒化的紫外线滤光剂的局部组合物。(The invention relates to a topical composition comprising panthenol, a silicone-based UV filter and a micronized UV filter in specific proportions.)
1. A topical composition comprising panthenol, a micronized uv-filter and a silicone based uv-filter, characterized in that the amount of panthenol in the topical composition is at least equal (or higher) compared to the amount of the silicone based uv-filter and/or the amount of the micronized uv-filter.
2. The topical composition of claim 1, wherein the micronized uv filter has an average particle size distribution D of less than 200nm as determined by light scatteringv50。
3. The topical composition according to claim 1 or 2, wherein the micronized uv-filter is a micronized insoluble organic uv-filter.
4. The topical composition according to any one of claims 1 to 3, wherein the micronized uv-filter is used as an aqueous dispersion of particles comprising the micronized uv-filter.
5. The topical composition of claim 4, wherein the aqueous dispersion comprising a micronized uv filter additionally comprises C8-16An alkyl polyglucoside.
6. The topical composition according to any one of claims 1 to 5, wherein the micronized UV-filter is methylenebis-benzotriazolyl tetramethylbutylphenol or terphenyltriazine.
7. The topical composition according to any one of claims 1 to 6, wherein the silicone based UV filter is a compound according to formula Ia or Ib:
wherein
X is R or A;
a is selected from formula IIa, IIb or IIc:
r is hydrogen, C1-6-alkyl or phenyl;
R1and R2Each independently is hydrogen, hydroxy, C1-6-alkyl or C1-6-an alkoxy group;
R3is C1-6-an alkyl group;
R4is hydrogen or C1-6-an alkyl group;
R5and R6Each independently is hydrogen or C1-6-an alkyl group;
r is 0 to 250;
s is 0 to 20;
r + s is at least 3;
t is 0 to 10;
v is 0 to 10;
v + t is at least 3; and is
n is 1 to 6;
provided that when s is 0, at least one X is A.
8. The topical composition according to any one of claims 1 to 7, wherein the silicone-based UV-filter is silicone-15.
9. The topical composition according to any one of claims 1 to 8, wherein the amount of the micronized uv-filter (based on active substance) is selected from the range of 0.1 to 9 wt. -%, preferably from the range of 0.5 to 7 wt. -%, more preferably from the range of 1 to 6 wt. -%, most preferably from the range of 1 to 5 wt. -%, based on the total weight of the composition.
10. The topical composition according to any one of claims 1 to 9, wherein panthenol is present in the topical composition in an amount selected from the range of 0.1 to 10 wt. -%, preferably in the range of 0.5 to 8 wt. -%, more preferably in the range of 1 to 7 wt. -%, most preferably in the range of 2 to 6 wt. -%, based on the total weight of the composition.
11. The topical composition according to any one of claims 1 to 10, wherein the silicone-based uv-filter is present in the topical composition in an amount selected from the range of 0.1 to 9 wt. -%, preferably in the range of 0.5 to 7 wt. -%, more preferably in the range of 1 to 6 wt. -%, most preferably in the range of 1 to 5 wt. -%, based on the total weight of the composition.
12. The topical composition of any one of claims 1 to 11, wherein the composition is in the form of an oil-in-water (O/W) emulsion comprising an oil phase dispersed in an aqueous phase in the presence of an O/W emulsifier.
13. The topical composition of any one of claims 1 to 12, wherein the topical composition further comprises butyl methoxydibenzoylmethane, octocrylene, and ethylhexyl salicylate.
14. Use of panthenol, a micronised uv-filter and a polysiloxane-based uv-filter in a topical composition for reducing the transfer of said topical composition to a glass or plastic surface.
15. A method of reducing the transfer of fats and/or oils to a surface, such as in particular a glass or plastic surface, the method comprising adding to a topical composition comprising said fats and oils panthenol, a micronised uv-filter and a polysiloxane-based uv-filter.