阅读说明：本技术 执行超声成像的方法和系统 (Method and system for performing ultrasound imaging ) 是由 吉挺澜 刘东来 格伦·W·马克劳林 于 2020-01-08 设计创作，主要内容包括：提供了执行超声成像的系统和方法,采集用于执行对象区域的超声成像的主通道域数据以执行该对象区域的超声成像。此外,采集用于执行该对象区域内的感兴趣区域(“ROI”)的超声成像的ROI通道域数据。可以使用该主通道域数据来形成对象区域的一个或多个超声图像。此外,可以使用该对象区域内的ROI的ROI通道域数据与该对象区域的该一个或多个主超声图像独立地形成该对象内的ROI的一个或多个ROI超声图像。随后,该一个或多个ROI超声图像可以被与该一个或多个主超声图像同时显示。(Systems and methods are provided for performing ultrasound imaging that acquire main channel domain data for performing ultrasound imaging of a subject region to perform ultrasound imaging of the subject region. Furthermore, ROI channel region data for performing ultrasound imaging of a region of interest ("ROI") within the region of interest is acquired. The main channel domain data may be used to form one or more ultrasound images of the object region. Further, one or more ROI ultrasound images of the ROI within the object may be formed using the ROI channel domain data of the ROI within the object region independently of the one or more master ultrasound images of the object region. Subsequently, the one or more ROI ultrasound images may be displayed simultaneously with the one or more master ultrasound images.)

1. A method of performing ultrasound imaging, comprising:

acquiring main channel domain data of a subject region for performing ultrasound imaging of the subject region;

acquiring region of interest ("ROI") channel domain data for performing ultrasound imaging of a ROI within the object region;

forming one or more master ultrasound images of the object region using the master channel domain data;

forming one or more ROI ultrasound images of the ROI within the object region independently of the one or more master ultrasound images of the object region using the ROI channel domain data of the ROI within the object region; and

displaying the one or more ROI ultrasound images simultaneously with the one or more master ultrasound images.

2. The method of claim 1, wherein the one or more ROI ultrasound images are formed independently of the one or more main ultrasound images by changing ROI data acquisition parameters used to acquire the ROI channel domain data relative to main channel domain data acquisition parameters used to acquire the main channel domain data.

3. The method of claim 2, wherein the ROI data acquisition parameters include transmit and receive imaging parameters.

4. The method of claim 3, wherein first transmit and receive parameters used to acquire the ROI channel domain data are varied with respect to second transmit and receive parameters used to acquire main channel domain data.

5. The method of claim 2, wherein the ROI data acquisition parameters include one or a combination of a transmit frequency of ultrasound waves, a transmit waveform design of the ultrasound waves, a front-end analog gain, and a transmit aperture and focus design for acquiring the ROI data.

6. The method of claim 2, wherein a frame rate at which the one or more ROI ultrasound images are formed is greater than a frame rate at which the one or more master ultrasound images are formed.

7. The method of claim 1, wherein the one or more ROI ultrasound images are formed independently of the one or more master ultrasound images by changing ROI imaging parameters used to form the one or more ROI ultrasound images relative to master frame imaging parameters used to form the one or more master ultrasound images.

8. The method of claim 1, wherein the one or more ROI ultrasound images, when formed separately from the one or more master ultrasound images, have one or a combination of increased spatial resolution, increased contrast resolution, increased temporal resolution, and increased penetration resolution as compared to the one or more master ultrasound images.

9. The method of claim 1, wherein the one or more ROI ultrasound images are formed independently of the one or more master ultrasound images by generating the one or more ROI ultrasound images by applying a different back-end process than that used to generate the one or more master ultrasound images.

10. The method of claim 1, further comprising:

receiving ROI control input from an operator; and

selecting a region within the object region to be used as ROI based on the ROI control input received from an operator.

11. The method of claim 10, wherein the ROI control input includes magnification instructions for magnifying the one or more ROI images, the method further comprising:

magnifying the one or more ROI images according to the magnification instructions to generate one or more magnified ROI images; and

simultaneously displaying the one or more magnified ROI images and the one or more master ultrasound images.

12. The method of claim 11, wherein the magnification instructions include a magnification scale factor for magnifying the one or more ROI images to generate the one or more magnified ROI images.

13. The method of claim 11, wherein the magnification instructions include a magnification region within the ROI for magnifying within the one or more ROI images to generate the one or more magnified ROI images.

14. The method of claim 10, wherein the ROI control input specifies either or both of a shape and a size of the region within the object region to be used as the ROI.

15. The method of claim 1, wherein the one or more ROI ultrasound images are displayed within the one or more master ultrasound images while simultaneously displayed with the one or more master ultrasound images.

16. The method of claim 15, wherein the one or more ROI ultrasound images are displayed in a region in the one or more master ultrasound images corresponding to the ROI within the one or more master ultrasound images.

17. The method of claim 1, wherein the one or more ROI ultrasound images are displayed adjacent to the one or more ultrasound images when displayed simultaneously with the one or more master ultrasound images.

18. The method of claim 1, wherein the one or more master ultrasound images and the one or more ROI ultrasound images are generated using B-mode ultrasound imaging, contrast enhanced ultrasound imaging, CD-mode ultrasound imaging, 2D ultrasound imaging, 3D ultrasound imaging, or 4D ultrasound imaging.

19. A system for performing ultrasound imaging, comprising:

an ultrasound transducer configured to:

acquiring main channel domain data for performing ultrasound imaging of a region of an object;

acquiring region of interest ("ROI") channel domain data for performing ultrasound imaging of a ROI within the object region;

a main processing console configured to:

forming one or more master ultrasound images of the object region using the master channel domain data;

forming one or more ROI ultrasound images of the ROI within the object region independently of the one or more master ultrasound images of the object region using the ROI channel domain data of the ROI within the object region; and

displaying the one or more ROI ultrasound images simultaneously with the one or more master ultrasound images.

20. A system for performing ultrasound imaging, comprising:

one or more processors; and

a computer-readable medium providing instructions accessible to the one or more processors to cause the one or more processors to perform operations comprising:

acquiring main channel domain data for performing ultrasound imaging of a region of an object;

acquiring region of interest ("ROI") channel domain data for performing ultrasound imaging of a ROI within the object region;

forming one or more master ultrasound images of the object region using the master channel domain data;

forming one or more ROI ultrasound images of the ROI within the object region independently of the one or more master ultrasound images of the object region using the ROI channel domain data of the ROI within the object region; and

displaying the one or more ROI ultrasound images simultaneously with the one or more master ultrasound images.

Technical Field

The present invention relates to ultrasound imaging. In particular, the present invention relates to forming a master ultrasound image of an object region and separately forming an ROI ultrasound image of an ROI within the object region for simultaneous display with the master ultrasound image.

Background

Ultrasound imaging is widely used to inspect various materials and objects in a variety of different applications. Ultrasound imaging provides a fast and easy tool to analyze materials and objects in a non-invasive manner. Therefore, ultrasound imaging is particularly prevalent in medical practice as a disease diagnosis, treatment, and prevention tool. In particular, ultrasound imaging is widely used throughout the medical industry for diagnosis and prevention of disease due to its relatively non-invasive nature, low cost, and fast response time. Moreover, since ultrasound imaging is based on non-ionizing radiation, it does not carry the same risks as other diagnostic imaging tools (e.g., X-ray imaging or other imaging systems that use ionizing radiation).

In many ultrasound applications, a particular region of interest within an ultrasound image of an object region is more important than other regions in the object region. For example, when imaging a tumor, the tumor itself is more meaningful to the physician than a non-tumor region. Accordingly, it would be beneficial to provide the operator with image enhancement functionality (e.g., increasing image resolution) for the ROI of the region of interest in the ultrasound image.

Acoustic zooming, also known as front-end zooming, has been used to magnify a portion of an ultrasound image within a user-specified ROI so that the user can better visualize the details of the portion of the image that includes the ROI. In particular, since the selected ROI box is typically smaller than the full size image, which typically means fewer transmit triggers and fewer receive lines, the user may obtain a higher frame rate image (e.g., improved temporal resolution) of the ROI. However, acoustic zoom techniques for enhanced imaging in the ROI have drawbacks. In particular, by acoustic scaling techniques, only the scaled image portion is displayed. Thus, the relationship between the zoomed image portion and the rest of the entire image is lost, which is detrimental to the ultrasound operator.

Alternatively, the ultrasound image may be magnified by linear interpolation to enhance the image within the ROI. This magnification is commonly referred to as back-end zooming or display zooming. There are also deficiencies in magnifying an ultrasound image to create an enhanced ultrasound image. In particular, the zoomed image portion of the ultrasound image created using interpolation has no enhanced image quality other than magnification.

Accordingly, there is a need for a system and method that facilitates enhanced ultrasound imaging, not just magnification enhancement, while allowing for the simultaneous display of an enhanced ultrasound image and a master ultrasound image.

Disclosure of Invention

According to various embodiments, a method of performing ultrasound imaging includes acquiring main channel domain data of a subject region for performing ultrasound imaging of the subject region. Furthermore, ROI channel domain data for ultrasound imaging of the ROI within the region of the object may be acquired. The main channel domain data may be used to form one or more main ultrasound images of the object region. In addition, one or more ROI ultrasound images within the object region may be formed independently of the one or more master ultrasound images within the object region using ROI channel domain data of the ROI within the object region. The one or more ROI ultrasound images may be displayed simultaneously with the one or more master ultrasound images.

In some embodiments, a system for performing ultrasound imaging includes an ultrasound transducer and a main processing console. The ultrasound transducer may be configured to acquire main channel domain data for performing ultrasound imaging of the object region. Furthermore, the ultrasound transducer may be configured to acquire ROI channel domain data for performing ultrasound imaging of the ROI within the region of the object. The master processing console may be configured to use the master channel domain data to form one or more master ultrasound images of the object region. Further, the master processing console may be configured to form one or more ROI ultrasound images of the ROI within the object region using the ROI channel domain data of the ROI within the object region independently of the one or more master ultrasound images of the object region. The main processing console may also be configured to simultaneously display the one or more main ultrasound images and the one or more ROI ultrasound images.

In various embodiments, a system for performing ultrasound imaging includes one or more processors and a computer-readable medium providing instructions accessible to the one or more processors to cause the one or more processors to perform operations including acquiring primary channel domain data for performing ultrasound imaging of a region of an object. The instructions may also cause the one or more processors to acquire ROI channel domain data for performing ultrasound imaging of a ROI within the region of the object. Further, the instructions may cause the one or more processors to form one or more master ultrasound images of the object region using the master channel domain data. The instructions may also cause the one or more processors to form one or more ROI ultrasound images of the ROI within the object region using ROI channel domain data of the ROI within the object independently of the one or more master ultrasound images of the object region. Further, the instructions may cause the one or more processors to simultaneously display the one or more master ultrasound images and the one or more ROI ultrasound images.

Drawings

Fig. 1 shows an example of an ultrasound system.

FIG. 2 is a flow chart of an example method for enhancing an ultrasound image of an ROI within a region of interest and displaying the ROI ultrasound image simultaneously with a master ultrasound image of the region of interest.

Fig. 3 shows an example imaging sequence of an ROI ultrasound frame and a main ultrasound frame acquired according to varying data acquisition parameters.

Fig. 4 shows another example imaging sequence of an ROI ultrasound frame and a main ultrasound frame acquired according to varying data acquisition parameters.

Fig. 5 shows yet another example imaging sequence acquired according to varying acquisition parameters.

Fig. 6 shows an exemplary ultrasound image display format in which an ROI ultrasound image (e.g., an enhanced ROI ultrasound image) is displayed within the master ultrasound image.

Fig. 7 shows an exemplary ultrasound image display format in which an ROI ultrasound image (e.g., an enhanced ROI ultrasound image) is displayed adjacent to the master ultrasound image.

Fig. 8 shows another exemplary flow chart of an exemplary method for generating an ROI ultrasound image of an object region independently of a master ultrasound image of the object region to simultaneously display the ROI ultrasound image and the master ultrasound image.

Detailed Description

According to various embodiments, a method of performing ultrasound imaging includes acquiring main channel domain data of a subject region for performing ultrasound imaging of the subject region. Furthermore, ROI channel domain data for performing ultrasound imaging of the ROI within the region of the object may be acquired. The main channel domain data may be used to form one or more main ultrasound images of the object region. In addition, one or more ROI ultrasound images within the object region may be formed independently of the one or more master ultrasound images within the object region using ROI channel domain data of the ROI within the object region. The one or more ROI ultrasound images and the one or more master ultrasound images may be displayed simultaneously.

In some embodiments, a system for performing ultrasound imaging includes an ultrasound transducer and a main processing console. The ultrasound transducer may be configured to acquire main channel domain data for performing ultrasound imaging of a region of a subject. Furthermore, the ultrasound transducer may be configured to acquire ROI channel domain data for performing ultrasound imaging of the ROI within the region of the object. The main processing console may be configured to use the main channel domain data to form one or more main ultrasound images of the object region. Further, the master processing console may be configured to form one or more ROI ultrasound images of the ROI within the object region independently of the one or more master ultrasound images of the object region using ROI channel domain data of the ROI within the object region. The main processing console may also be configured to display the one or more ROI ultrasound images simultaneously with the one or more main ultrasound images.

In various embodiments, a system for performing ultrasound imaging includes one or more processors and a computer-readable medium providing instructions accessible to the one or more processors to cause the one or more processors to perform operations including acquiring primary channel domain data for performing ultrasound imaging of a region of an object. The instructions may also cause the one or more processors to acquire ROI channel domain data for performing ultrasound imaging of a ROI within the region of the object. Additionally, the instructions may cause the one or more processors to form one or more master ultrasound images of the object region using the master channel domain data. The instructions may also cause the one or more processors to form one or more ROI ultrasound images of the ROI within the object region using ROI channel region data of the ROI within the object region independently of the one or more master ultrasound images of the object region. Further, the instructions may cause the one or more processors to display the one or more ROI ultrasound images simultaneously with the one or more master ultrasound images.

Some infrastructure has become available that can be used with the embodiments of the present disclosure, such as general purpose computers, computer programming tools and techniques, digital storage media and communication networks.

Aspects of some embodiments may be implemented using hardware, software, firmware, or a combination thereof. As used herein, a software module or component may include any type of computer instruction or computer executable code located within or on a computer readable storage medium. A software module may, for instance, comprise one or more physical or logical blocks of computer instructions, which may be organized as a routine, program, object, component, data structure, etc., that performs one or more tasks or implements particular abstract data types.

In some embodiments, particular software modules may include different instructions stored in different locations on a computer-readable storage medium that together implement the described module functions. Indeed, a module may comprise a single instruction, or many instructions, and may be distributed over several different code segments, among different programs, and across several computer-readable storage media. Some embodiments may be practiced in distributed computing environments where tasks are performed by remote processing devices that are linked through a communications network.

The disclosed embodiments of the invention will be best understood by referring to the drawings. The components of the disclosed embodiments, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations. Furthermore, features, structures, or operations associated with one embodiment may be applied to, or combined with, features, structures, or operations described in another embodiment. In other instances, well-known structures, materials, or operations are not shown or described in detail to avoid obscuring aspects of the invention.

Thus, the following detailed description of the embodiments of the systems and methods of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of possible embodiments. In addition, the steps of the method need not necessarily be performed in any particular order, even sequentially, nor need the steps be performed only once.

Fig. 1 shows an example of an ultrasound system 100. The ultrasound system 100 shown in figure 1 is merely an exemplary system and, in different embodiments, the ultrasound system 100 may have fewer components or additional components. In particular, the ultrasound system 100 may be an ultrasound system in which the receive array focusing unit is referred to as a beam combiner 102 and image formation may be performed on a scanline-by-scanline basis. System control may be centralized in a master controller 104 that accepts operator input through an operator interface to control the various subsystems. For each scan line, a Radio Frequency (RF) excitation voltage pulse waveform is generated by the transmitter 106 and applied to the transmit apertures (defined by the sub-arrays of active array elements) at the appropriate timing to produce a focused acoustic beam in the scan direction. The RF echoes received by the receive apertures 108 of the transducers 110 are amplified and filtered by the receivers 108 and then fed to the beamformer 102, the function of the beamformer 102 being to perform dynamic receive focusing, i.e., to realign the RF signals from the same location along the various scanlines.

Image processor 112 may perform processing specific to the active imaging mode, including 2D scan conversion to convert image data from a sound ray grid to an X-Y pixel image for display. For spectral doppler mode, the image processor 112 may perform wall filtering followed by spectral analysis of the doppler shifted signal samples, typically using a sliding FFT window. The image processor 112 may also generate stereo audio signal outputs corresponding to the forward and reverse blood flow signals. In cooperation with the master controller 104, the image processor 112 may also format images from two or more active imaging modes, including displaying annotations, graphic overlays, and playback of movie files and recorded timeline data.

The cine buffer 114 provides resident digital image storage for loop viewing of a single image or multiple images and serves as a buffer for transferring images to a digital archival device. On most systems, the video images at the end of the data processing path can be stored in a cine memory. In state-of-the-art systems, amplitude detected beamformed data may also be stored in cine memory 114. For spectral doppler, the wall filtered baseband doppler I/Q data at the user selected sampling gate may be stored in cine memory 114. Subsequently, display 116 may display the ultrasound images created by image processor 112 and/or images created using data stored in cine memory 114.

The beam synthesizer 102, the master controller 104, the image processor 112, the cine memory 114, and the display may be included as part of a master processing console 118 of the ultrasound system 100. In various embodiments, the main processing console 118 may include more or fewer components or subsystems. The ultrasound transducer 110 may be incorporated in a device separate from the main processing console 118, for example, in a separate device that is wired or wirelessly connected to the main processing console 118. This allows for easier manipulation of the ultrasound transducer 110 when performing a particular ultrasound procedure on a patient. Further, the transducer 110 may be an array transducer comprising an array of transmit and receive array elements for transmitting and receiving ultrasound waves.

FIG. 2 is a flowchart 200 of an example method for enhancing an ultrasound image of an ROI within a region of interest and displaying the ROI ultrasound image simultaneously with a master ultrasound image of the region of interest. The example method shown in fig. 2 and other methods and techniques for ultrasound imaging described herein may be performed by a suitable ultrasound imaging system, such as the ultrasound system 100 shown in fig. 1. For example, the example methods and techniques for ultrasound imaging described herein may be implemented using one or both of the ultrasound transducer 110 and the main processing console 118 (e.g., image processor 112) of the ultrasound system 100.

As previously mentioned, in many ultrasound applications, a particular region of interest within an ultrasound image of an object region is more important than other regions in the object region. For example, when imaging a tumor, the tumor itself is more meaningful to the physician than a non-tumor region. Therefore, it would be beneficial to provide the operator with image enhancement functionality (e.g., improving image resolution) of the ROI of the region of interest in the ultrasound image.

Acoustic zooming, also known as front-end zooming, has been used to magnify a portion of an ultrasound image within a user-specified ROI so that the user can better visualize the details of the portion of the image that includes the ROI. In particular, since the selected ROI box is typically smaller than the full size image, which typically means fewer transmit triggers and fewer receive lines, the user may obtain a higher frame rate image (e.g., improved temporal resolution) of the ROI. However, acoustic zoom techniques for enhanced imaging in the ROI have drawbacks. In particular, by acoustic scaling techniques, only the scaled image portion is displayed. Thus, the relationship between the zoomed image portion and the rest of the entire image is lost, which is detrimental to the ultrasound operator.

Alternatively, the ultrasound image may be magnified by linear interpolation to enhance the image within the ROI. This magnification is commonly referred to as back-end zooming or display zooming. There are also deficiencies in magnifying an ultrasound image to create an enhanced ultrasound image. In particular, the zoomed image portion of the ultrasound image created using interpolation has no enhanced image quality other than magnification.

The present invention includes ultrasound imaging techniques and systems for implementing techniques that facilitate independent creation of ultrasound images of ROIs within a region of an object. Subsequently, the independently formed ROI ultrasound image may be displayed simultaneously with the master ultrasound image of the object region. When formed separately from the master ultrasound image, the ROI ultrasound image may be enhanced as compared to the master ultrasound image. As used herein, enhancing/augmenting may include altering/augmenting the applicable characteristics of the ultrasound image, such as increasing spatial resolution, increasing contrast resolution, increasing temporal resolution, and increasing penetration resolution, as compared to the master ultrasound image. For example, and as will be discussed in more detail later, the ROI ultrasound image may be processed to have an improved spatial resolution compared to the master ultrasound image. This is advantageous compared to typical magnification techniques for enhancing ultrasound images, which only have an increased magnification.

The master ultrasound image and the ROI ultrasound image (e.g., the enhanced ROI ultrasound image) that is generated independently from the master ultrasound image may be simultaneously displayed. This may allow the operator to examine both the entire object region and the ROI within the object region at the same time. This is advantageous over typical acoustic scaling techniques where the relationship between the ROI ultrasound image and the master ultrasound image is lost, which is detrimental to the ultrasound operator.

Returning to the example flowchart 200 shown in fig. 2. In step 202, main channel domain data of a subject region for performing ultrasound imaging of the subject region is acquired. Main channel domain data of the subject region may be acquired by a suitable ultrasound transducer, such as ultrasound transducer 110 shown in fig. 1. As used herein, channel domain data includes data generated from transducer elements and from each transmit/receive cycle used to generate ultrasound images. For example, in a 128 channel system using a single focal zone and sampling to a depth of 16 centimeters in a curved array format, there may be approximately 192 transmit receive cycles. The channel domain data may include data used to generate ultrasound images prior to any processing of the data. For example, the channel domain data may include data generated by the transducer before pre-processing the data for beamforming, before actually beamforming, and/or after beamforming to post-process the data for generating an ultrasound image.

In step 204, ROI channel domain data for performing ultrasound imaging of the ROI within the region of the object is acquired. ROI channel region data of the ROI within the object region may be acquired by a suitable ultrasound transducer, such as ultrasound transducer 110 shown in fig. 1. The ROI in the object region may comprise a subset of the object region. In particular, the ROI in the object region may comprise a subset of the object region rendered in the one or more master ultrasound images.

ROI channel domain data of the ROI within the region of the object may be acquired by changing ROI data acquisition parameters used for collecting/acquiring/generating the ROI channel domain data. In particular, the ROI channel domain data may be acquired by changing ROI data acquisition parameters relative to main channel domain data acquisition parameters used for acquiring main channel domain data of the object region. The data acquisition parameters may include applicable parameters for acquiring channel domain data by the ultrasound transducer. In particular, the data acquisition parameters may include transmit and receive imaging parameters for collecting channel domain data. More specifically, the data acquisition parameters may include the transmit frequency of the ultrasound waves used to collect the channel domain data, the transmit waveform design of the ultrasound waves, the front-end analog gain, and the transmit aperture and focus design. For example, ROI data may be acquired with an ultrasound focus that is larger than the focus of the ultrasound used to acquire the main ultrasound data. In another example, ROI data may be acquired using ultrasound waves of a first waveform design, while primary ultrasound data may be acquired using ultrasound waves of a second waveform design different from the first waveform design used to acquire ROI data.

At step 206, one or more master ultrasound images of the object region are formed using the master channel domain data. In particular, a sonication operation may be applied to the main channel domain data to generate one or more main ultrasound images. The sonication operations may include applicable operations applied to the channel domain data for the purpose of generating one or more ultrasound images. In particular, the sonication operations may include applicable operations applied to the channel domain data before post-beamforming data processing/back-end processing is applied to generate one or more ultrasound images. More specifically, the sonication operations may include data operations applied to generate beamformed data from the channel domain data, which may then be post-processed to form one or more ultrasound images. Additionally, as described herein, the sonication operation may include a plurality of sub-operations. In particular, the sonication operation may include a plurality of operations applied to the channel domain data to process the data according to the sonication operation. For example, the sonication operation may include a least-variance operation and a phase-coherent operation applied to the channel-domain data as part of the overall sonication operation.

Further, the sonication operations may include operations for beamforming the channel domain data. In particular, the sonication operations may include beamforming operations for ultimately creating beamformed data from the channel domain data. For example, the sonication operation may be a coherent beam-forming operation, a digital beam-forming operation, a synthetic aperture beam-forming operation or an adaptive beam-forming operation.

Additionally, the sonication operation may include post-processing/post-beamforming data processing. The back-end processing may include suitable operations for forming an ultrasound image from the beamformed data. For example, back-end processing may include upsampling, downsampling, log compression, detection, spatial filtering, adaptive filtering, scan conversion, and so forth, which facilitate display of ultrasound image data.

At step 208, one or more ROI ultrasound images of the ROI are formed from ROI channel domain data of the ROI within the region of interest. In particular, one or more ROI ultrasound images of the ROI may be formed independently of the one or more master ultrasound images. More specifically, sonication operations may be applied to the ROI channel domain data to form one or more ROI ultrasound images independent of the ROI of the one or more master ultrasound images. When the ROI ultrasound image is formed separately from the master ultrasound image, the ROI ultrasound image may be formed by enhancing a different aspect of the image, rather than simply enlarging the master ultrasound image. For example, the ROI image may have improved spatial resolution, improved contrast resolution, improved temporal resolution, and improved penetration resolution compared to the master ultrasound image. In addition, by forming the ROI ultrasound image separately from the master ultrasound image, as will be discussed in more detail later, the ROI ultrasound image and the master ultrasound image can be displayed simultaneously.

By controlling the changed ROI data acquisition parameters used for acquiring the ROI channel domain data relative to the main channel domain data acquisition parameters used for acquiring the main channel domain data, the ROI ultrasound image can be formed independently of the main ultrasound image. In particular, ROI channel domain data may be acquired independently of the main channel domain data according to ROI channel domain acquisition parameters, and may be used to independently form an ROI ultrasound image. For example, ROI channel domain data may be acquired using a higher ultrasound transmit frequency than the ultrasound frequency used to acquire the main channel domain data of the subject region. Subsequently, the ROI channel domain data acquired at the higher ultrasound transmit frequency can be used to generate the ROI ultrasound image independently of the master ultrasound image.

Fig. 3 shows an example imaging sequence 300 of ROI ultrasound frames and main ultrasound frames acquired according to varying data acquisition parameters. In particular, the exemplary imaging sequence 300 shown in fig. 3 may be used to generate an ROI ultrasound image independently of the master ultrasound image. In particular, both transmit and receive imaging parameters may be selected to provide an ROI image with enhanced spatial resolution with minimal impact on the overall frame rate of the master ultrasound image. More specifically, in the example imaging sequence 300, the T2 for ROI frame acquisition is less than the T1/is a fraction of T1 for the primary frame acquisition. The resulting frame rate is given by equation 1 below.

1/T = 1/(T₁+ T₂)<1/ T₁.

Equation 1

Therefore, the main frame and the ROI frame can be matched one-to-one at the same frame rate to make correlation between the ROI ultrasound image and the main ultrasound image easier. This is advantageous because the ROI frame has a higher TX region density and a higher RX line density for stronger focusing and better spatial resolution, e.g., corresponding to an enhanced ROI ultrasound image.

Fig. 4 shows another example imaging sequence 400 of an ROI ultrasound frame and a main ultrasound frame acquired according to varying data acquisition parameters. In the imaging sequence 400 shown in fig. 4, the frame rate within the ROI is updated faster than the frame of the primary ultrasound image of the subject region. In particular, the master ultrasound frame rate acquisition for the master ultrasound image may be divided into K groups (e.g., P1, P2, P3). The ROI frame time is 1/K of the primary frame time, as shown in equation 2 below.

T₃= T/K (e.g., K = 3 in the figure)

Equation 2

Therefore, the ROI frame rate is K × main frame rate. Furthermore, this may significantly improve the temporal resolution of the image portion within the ROI compared to the master ultrasound image.

Fig. 5 shows yet another example imaging sequence 500 acquired according to varying acquisition parameters. The example imaging sequence 500 shown in fig. 5 generates a master frame using Plane Wave Imaging (PWI). As a result, T1 was shorter than T2. The resulting frame rate is represented by equation 3 below.

1/T = 1/(T₁+ T₂)

Equation 3

In particular, the resulting frame rate may be much faster than that of conventional full-scale B-mode imaging. However, the ROI frame may still use the focused TX beam and higher TX region density for better focus and/or higher frequency than the master ultrasound image of the object region, resulting in enhanced resolution in the ROI ultrasound image. In particular, both spatial resolution and temporal resolution may be enhanced for the ROI ultrasound image when compared to the master ultrasound image.

Returning to the flow chart 200 shown in fig. 2. Imaging parameters for generating one or more ROI ultrasound images may be changed to generate one or more ROI ultrasound images independently of the one or more master ultrasound images. In particular, the imaging parameters used to generate the one or more ROI ultrasound images may be changed relative to the imaging parameters used to generate the one or more master ultrasound images in order to independently form the ROI ultrasound images. The imaging parameters include applicable parameters for controlling the application of the sonication operation to produce the ultrasound image. In particular, the imaging parameters may indicate a particular sonication operation to be applied to generate the ultrasound image and how the particular sonication operation is to be applied to generate the ultrasound image. For example, the imaging parameters may specify that a particular beamforming operation be applied to generate the ROI image. In another example, the imaging parameters may specify values of parameters of a particular beamforming operation to apply in generating the ROI image.

Further, the back-end processing may be altered to generate one or more ROI ultrasound images independently of the one or more master ultrasound images. In particular, a different back-end process than that used to produce the master ultrasound image may be applied to generate the ROI ultrasound image. For example, filtering may be applied to generate an ROI ultrasound image as compared to the master ultrasound image to further generate an enhanced ROI ultrasound image.

In step 210, the one or more ROI ultrasound images are displayed simultaneously with the one or more master ultrasound images. In particular, the one or more ROI ultrasound images and the one or more master ultrasound images may be displayed simultaneously in real time as the images are formed. By displaying the ROI ultrasound image and the master ultrasound image simultaneously, the user can more easily concentrate on the region image with enhanced image quality within a given ROI, and also obtain a visualization of the entire field of view of the object region. As previously discussed, this is advantageous over current ultrasound imaging techniques, where the relationship between the ROI image and the master ultrasound image is lost due to the creation of the ROI image by zooming in.

The ROI ultrasound image may be displayed within the master ultrasound image while simultaneously displayed with the master ultrasound image. In particular, fig. 6 shows an exemplary ultrasound image display format 600 in which an ROI ultrasound image 602 (e.g., an enhanced ROI ultrasound image) is displayed within a master ultrasound image 604. More specifically, the ROI ultrasound image 602 is rendered at the location where the ROI is actually displayed in the master ultrasound image 604, e.g., the region of the master ultrasound image 604 corresponding to the ROI. As will be discussed in more detail later, the ROI ultrasound image 602 itself may be further enlarged while still being displayed in the master ultrasound image 604.

Alternatively, the ROI ultrasound image may be displayed adjacent to the master ultrasound image when displayed simultaneously with the master ultrasound image. Fig. 7 shows an example ultrasound image display format 700 in which an ROI ultrasound image 702 (e.g., an enhanced ROI ultrasound image) is displayed adjacent to a master ultrasound image 704. As will be discussed in more detail later, the ROI ultrasound image 702 itself may be further enlarged while still being displayed adjacent to the master ultrasound image 704. The image display format 700 includes an indicator, such as a dashed box, that shows the ROI in the master ultrasound image 704. The indicator may be movable by an operator. The ROI ultrasound image 702 can then be updated based on the movement of the pointer to display the new ROI covered by the pointer. Using the techniques described herein, the ROI ultrasound image 702 can be updated based on the position and shape of the pointer selected by the user.

Returning to fig. 2, the various techniques described with reference to flowchart 200 shown in fig. 2 may be performed based on input received from an operator/user. In particular, the operator may provide input, such as ROI control input, for controlling the enhancement and display of the one or more ROI ultrasound images. The ROI control input can specify an ROI for imaging (e.g., in the master ultrasound image) to form the ROI ultrasound image independently of the master ultrasound image. For example, the ROI control input may specify the size and/or shape of the ROI within the region of the object for imaging to generate one or more ROI ultrasound images. In another example, the ROI control input may specify that the ROI be moved within the region of the object to effectively create a new ROI in order to generate an ultrasound image of the new ROI. In turn, an ultrasound processing system (such as main processing console 118) may select an ROI based on the received ROI control input and then generate an ultrasound image of the ROI independently of the main ultrasound image forming the region of the object.

The ROI control input may specify how the ultrasound image of the ROI is to be generated independently of the primary ultrasound image forming the region of interest. In particular, the ROI control input may specify one or a combination of data acquisition parameters for acquiring the ROI channel domain data, imaging parameters and corresponding sonication operations for generating the ROI ultrasound image independently of the master ultrasound image, and back-end processing applied in generating and displaying the ROI ultrasound image (e.g., displaying the ROI image concurrently with the primary ultrasound image). Furthermore, the ROI control input may specify different ways to enhance the ROI ultrasound image. In particular, the ROI ultrasound image may specify an increase in one or a combination of spatial resolution, contrast resolution, temporal resolution, and penetration resolution in the ROI ultrasound image as compared to the master ultrasound image of the object region. Accordingly, the user may control/select which aspects of the ROI to change when generating an ROI ultrasound image (e.g., an enhanced ROI ultrasound image) independently of the master ultrasound image of the object region. For example, the operator may provide an ROI control input to specify that the temporal resolution in the ROI ultrasound image is increased by an amount compared to the master ultrasound image of the object region.

Further, the ROI control input can include magnification instructions for magnifying an ROI image (e.g., an ROI image that has been enhanced according to the techniques described herein). In particular, the magnification instructions may specify a magnification scale factor for magnifying the ROI images (e.g., when they are currently displayed with the master ultrasound image). In addition, the magnification instructions may specify a region within the ROI to be magnified to generate a magnified ROI image. In turn, the applicable ultrasound processing system (e.g., main processing console 118) may magnify the ROI image according to the magnification instructions as part of the ROI control input. The enlarged ROI image may then be displayed simultaneously with the master ultrasound image of the object region.

Fig. 8 shows another exemplary flowchart 800 of an exemplary method for generating an ROI ultrasound image of an object region independently of a master ultrasound image of the object region to simultaneously display the ROI ultrasound image and the master ultrasound image. In step 802, primary frame data of the object region is acquired. At step 804, a full image/master ultrasound image is formed from the master frame data acquired at step 802. At step 806, the full image is processed and at step 808, the processed full image is scan converted for display.

Before or simultaneously with the preceding steps, in step 810, an ROI in the object region is selected. At step 812, ROI data for the selected ROI is acquired. At step 814, an ROI image is formed from the ROI data acquired at step 812. At step 814, an ROI image may also be formed using the main frame data acquired at step 802. At step 816, the ROI image is processed. At step 818, the processed ROI image is enlarged and scan converted for display. The ROI image may be enlarged based on ROI control input received from the operator. Finally, at step 820, after the scan conversion of steps 808 and 818, the ROI image and the full image are displayed simultaneously.

The techniques described herein, including the methods shown in fig. 2 and 8, may be applied in applicable ultrasound imaging modes, such as B-mode, Contrast Enhanced Ultrasound (CEUS), CD mode, 2D/3D/4D, and so forth. In particular, the techniques described herein are not limited to B-mode, but may also be applied to other modes in which improved temporal resolution within the region of interest has substantial clinical value, such as CEUS.

The invention has been described with reference to various exemplary embodiments including the best mode. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope of the present invention. For example, various operational steps, as well as components for performing the operational steps, may be implemented in alternative ways, e.g., one or more of the steps may be deleted, modified or combined with other steps, depending on the particular application or taking into account any number of cost functions associated with the operation of the system.

While the principles of the invention have been illustrated in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components may be used which are particularly adapted to specific environments and operative requirements without departing from the principles and scope of the present invention. These and other changes or modifications are intended to be included within the scope of the present invention.

The foregoing has been described with reference to various embodiments. However, one of ordinary skill in the art would appreciate that various modifications and changes may be made without departing from the scope of the present invention. Accordingly, the present disclosure is to be considered as illustrative and not restrictive, and all such modifications are intended to be included within the scope thereof. Benefits, other advantages, and solutions to problems have been described above with regard to various embodiments. However, the benefits, advantages, solutions to problems, and any element(s) that may cause any benefit, advantage, or solution to occur or become more pronounced are not to be construed as a critical, required, or essential feature or element. As used herein, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, system, article, or apparatus. Also, as used herein, the terms "coupled," "coupling," and any other variation thereof, are intended to cover a physical connection, an electrical connection, a magnetic connection, an optical connection, a communicative connection, a functional connection, and/or any other connection.

It will be appreciated by those skilled in the art that many changes could be made to the details of the above-described embodiments without departing from the underlying principles of the invention. Accordingly, the scope of the invention should be determined from the following claims.