阅读说明：本技术 一种灭菌消毒添加剂、灭菌消毒药水及其制备方法、涂覆有灭菌消毒药水的产品 (Sterilizing additive, sterilizing liquid medicine, preparation method of sterilizing liquid medicine and product coated with sterilizing liquid medicine ) 是由 赵文华 喻永元 杨启航 于 2020-04-23 设计创作，主要内容包括：本发明涉及一种灭菌消毒添加剂,其包含如下组成成分：重量比为30-40％的蒲公英的乙醇萃取物、重量比为20-30％的五味子的乙醇萃取物、重量比为10-20％的复合银离子胶体溶液、重量比为4-8％的季铵盐类、重量比为5-10％的磷酸盐类、重量比为0.1-2％的纳米二氧化钛粉体、以及重量比为0.5-2％的异噻唑啉酮或者苯并异噻唑啉酮或者两者的混合物。本发明还涉及一种灭菌消毒添加剂的制备方法。本发明还涉及含有灭菌消毒添加剂的灭菌消毒药水及其制备方法。本发明进一步涉及一种表面涂覆有灭菌消毒药水的产品。(The invention relates to a sterilization and disinfection additive, which comprises the following components: 30-40% of ethanol extract of dandelion, 20-30% of ethanol extract of schisandra chinensis, 10-20% of composite silver ion colloid solution, 4-8% of quaternary ammonium salt, 5-10% of phosphate, 0.1-2% of nano titanium dioxide powder and 0.5-2% of isothiazolinone or benzisothiazolinone or a mixture of the two. The invention also relates to a preparation method of the sterilizing and disinfecting additive. The invention also relates to a sterilizing liquid medicine containing the sterilizing additive and a preparation method thereof. The invention further relates to a product coated with a sterilizing and disinfecting liquid medicine.)

1. A sterilizing additive, which is characterized in that: the composition comprises the following components: 30-40% of ethanol extract of dandelion, 20-30% of ethanol extract of schisandra chinensis, 10-20% of composite silver ion colloid solution, 4-8% of quaternary ammonium salt, 5-10% of phosphate, 0.1-2% of nano titanium dioxide powder and 0.5-2% of isothiazolinone or benzisothiazolinone or a mixture of the two.

2. A sterilising additive as claimed in claim 1, wherein: the weight ratio of the dandelion ethanol extract is 35%, the weight ratio of the schisandra ethanol extract is 22%, the weight ratio of the composite silver ion colloid solution is 15%, the weight ratio of the quaternary ammonium salt is 6%, the weight ratio of the phosphate salt is 7%, the weight ratio of the nano titanium dioxide powder is 1%, and the weight ratio of the isothiazolinone or the benzisothiazolinone or the mixture of the isothiazolinone and the benzisothiazolinone is 1%.

3. A preparation method of a sterilization additive is characterized in that: the preparation method comprises the following steps:

step one, adding 30-40 wt% of ethanol extract of dandelion and 20-30 wt% of ethanol extract of schisandra chinensis into a reaction kettle, and stirring at low temperature for 15min to 1 h;

step two, sequentially mixing, dispersing and uniformly stirring 10-20 wt% of composite silver ion colloidal solution, 4-8 wt% of quaternary ammonium salt, 5-10 wt% of phosphate and 0.1-2 wt% of nano titanium dioxide powder for 15min-1 h;

step three, uniformly mixing the mixture obtained in the step two, adding the mixture into the reaction kettle obtained in the step one to perform dispersion mixing, heating to 50-55 ℃, keeping for 2 hours, stirring and mixing, and then cooling to 20 ℃;

step four, adding 0.5-2 wt% of isothiazolinone or benzisothiazolinone or a mixture of the isothiazolinone and the benzisothiazolinone into the product obtained in the step three; mixing uniformly, and performing closed low-temperature ultrasonic mixing reaction for 20min-1.5 h;

and step five, reducing the temperature to normal temperature to obtain the sterilization and disinfection additive product.

4. The sterilizing and disinfecting liquid medicine is characterized by comprising the following components: 5-15 wt% of the sterilization and disinfection additive as claimed in claim 1, 30-50 wt% of self-crosslinking polyacrylate emulsion, 7-15 wt% of nano-silica ethanol dispersion, 0.1-1 wt% of dispersant, 0.1-1 wt% of wetting agent, 0.1-2 wt% of curing agent, 10-20 wt% of silane coupling agent, 10-20 wt% of adhesion promoter, and 3-8 wt% of film-forming assistant.

5. A disinfectant fluid according to claim 1, wherein: the molecular formula of the dispersant is C₂₁H₁₄Na₂O₆Si₂。

6. A disinfectant fluid according to claim 1, wherein: the main component of the wetting agent is alkyl polyoxyethylene ether.

7. A disinfectant fluid according to claim 1, wherein: the silane coupling agent is gamma- (2, 3-glycidoxy) propyl trimethoxy silane.

8. A disinfectant fluid according to claim 1, wherein: the adhesion promoter comprises an easy Tech GT-2000 adhesion promoter produced by Shanghai Sanguin chemical Co., Ltd, or the curing agent comprises polyisocyanate, or the film-forming assistant comprises ethylene glycol phenyl ether.

9. A preparation method of a sterilization and disinfection liquid medicine is characterized by comprising the following steps: the preparation method comprises the following steps: the following components are added into 5-15 wt% of the sterilization additive as claimed in claim 1 by weight ratio: 7-15 wt% of nano silicon dioxide ethanol dispersion, 10-20 wt% of silane coupling agent, 30-50 wt% of self-crosslinking polyacrylate emulsion, 0.1-1 wt% of dispersing agent, 0.1-1 wt% of wetting agent, 0.1-2 wt% of curing agent, 10-20 wt% of adhesion promoter and 3-8 wt% of film forming assistant, and then mixing and stirring uniformly to prepare the sterilizing and disinfecting liquid medicine.

10. A product coated with the sterilizing agent of claim 4.

Technical Field

The invention relates to a sterilization and disinfection material and a preparation method thereof, in particular to a sterilization and disinfection additive with antimicrobial plant extract composition, a sterilization and disinfection liquid medicine and a preparation method thereof.

Background

The contact time of the mobile phone and the computer which are commonly used by people is long in daily use, the surfaces of the daily equipment are not coated with coatings with the sterilization and disinfection functions, and in the contact process, microorganisms on hands are transferred to the surfaces of electronic products such as the mobile phone and the like, so that the cleaning, the sterilization and disinfection effects are difficult to achieve, the sterilization and disinfection effects on the hands of users of the electronic products can not be basically achieved, the propagation of bacteria can not be inhibited and reduced, and the harm of the microorganisms to human bodies is reduced.

Therefore, there is a need to develop a sterilization material for forming a protective layer on the surface of an electronic product.

Disclosure of Invention

The invention aims to solve the technical problems that the existing sterilization additive has no continuous sterilization and disinfection performance, can not keep long-term effectiveness or achieve no long-term elimination of bacteria and reduction of virus propagation and the like

The technical problem to be solved by the invention is realized by the following technical scheme: the sterilizing and disinfecting additive comprises the following components: 30-40% of ethanol extract of dandelion, 20-30% of ethanol extract of schisandra chinensis, 10-20% of composite silver ion colloid solution, 4-8% of quaternary ammonium salt, 5-10% of phosphate, 0.1-2% of nano titanium dioxide powder and 0.5-2% of isothiazolinone or benzisothiazolinone or a mixture of the two.

Preferably, the weight ratio of the ethanol extract of dandelion is 35%, the weight ratio of the ethanol extract of schisandra chinensis is 22%, the weight ratio of the composite silver ion colloid solution is 15%, the weight ratio of quaternary ammonium salt is 6%, the weight ratio of phosphate is 7%, the weight ratio of nano titanium dioxide powder is 1%, and the weight ratio of isothiazolinone or benzisothiazolinone or the mixture of the isothiazolinone and the benzisothiazolinone is 1%.

The technical problem to be solved by the invention is realized by the following technical scheme: a preparation method of a sterilization additive is provided, and the preparation method comprises the following steps:

step one, adding 30-40 wt% of ethanol extract of dandelion and 20-30 wt% of ethanol extract of schisandra chinensis into a reaction kettle, and stirring at low temperature for 15min to 1 h;

step two, sequentially mixing, dispersing and uniformly stirring 10-20 wt% of composite silver ion colloidal solution, 4-8 wt% of quaternary ammonium salt, 5-10 wt% of phosphate and 0.1-2 wt% of nano titanium dioxide powder for 15min-1 h;

step three, uniformly mixing the mixture obtained in the step two, adding the mixture into the reaction kettle obtained in the step one to perform dispersion mixing, heating to 50-55 ℃, keeping for 2 hours, stirring and mixing, and then cooling to 20 ℃;

step four, adding 0.5-2 wt% of isothiazolinone or benzisothiazolinone or a mixture of the isothiazolinone and the benzisothiazolinone into the product obtained in the step three; mixing uniformly, and performing closed low-temperature ultrasonic mixing reaction for 20min-1.5 h;

and step five, reducing the temperature to normal temperature to obtain the sterilization and disinfection additive product.

The invention aims to solve another technical problem and provide a sterilizing liquid medicine and a preparation method thereof.

The other technical problem to be solved by the invention is realized by the following technical scheme: provides a sterilization and disinfection liquid medicine which comprises the following components: 5-15 wt% of sterilization and disinfection additive, 30-50 wt% of self-crosslinking polyacrylate emulsion, 7-15 wt% of nano silicon dioxide ethanol dispersion, 0.1-1 wt% of dispersant, 0.1-1 wt% of wetting agent, 0.1-2 wt% of curing agent, 10-20 wt% of silane coupling agent, 10-20 wt% of adhesion promoter and 3-8 wt% of film-forming assistant.

Preferably, the dispersant has the formula C₂₁H₁₄Na₂O₆Si₂。

Preferably, the main component of the wetting agent is alkyl polyoxyethylene ether.

Preferably, the silane coupling agent is gamma- (2, 3-glycidoxy) propyl trimethoxysilane.

Preferably, the adhesion promoter comprises an easy TechGT-2000 adhesion promoter, manufactured by Shanghai Sanger Wellkulturen chemical Co.

Preferably, the curing agent comprises a polyisocyanate.

Preferably, the coalescent includes ethylene glycol phenyl ether.

The other technical problem to be solved by the invention is realized by the following technical scheme: a preparation method of a sterilization and disinfection liquid medicine is provided, and the preparation method comprises the following steps: the following components are added into 5-15 wt% of the sterilizing and disinfecting additive by weight: 7-15 wt% of nano silicon dioxide ethanol dispersion, 10-20 wt% of silane coupling agent, 30-50 wt% of self-crosslinking polyacrylate emulsion, 0.1-1 wt% of dispersing agent, 0.1-1 wt% of wetting agent, 0.1-2 wt% of curing agent, 10-20 wt% of adhesion promoter and 3-8 wt% of film forming assistant, and then mixing and stirring uniformly to prepare the sterilizing and disinfecting liquid medicine.

Compared with the prior art, the invention has the following advantages: the dandelion ethanol extract and the schisandra ethanol extract in the formula have antibacterial and antiviral effects, and have inhibitory effects on staphylococcus aureus, hemolytic streptococcus, pneumococcus, pseudomonas aeruginosa, denatured bacillus, catacoccus, tubercle bacillus, influenza virus and various dermatophytes, the antiviral capability of the dandelion ethanol extract and the schisandra ethanol extract is improved by adding nano titanium dioxide photocatalyst and the synergistic effect of silver ion components, so that the dandelion ethanol extract and the schisandra ethanol extract have the inactivation effect on various viruses, and the isothiazolinone or/and benzisothiazolinone are added to keep the long-term sterilization and disinfection functions of the plant extracts.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

The invention relates to a preparation method and application of a sterilization and disinfection material, which are specially used for aiming at microbial source pollution, can eliminate, reduce and inhibit bacteria, fungi, yeasts and viruses on the product surfaces of industrial products (electronic products, automobiles and the like), medical supplies and living goods (home furnishing, clothing and the like) or in the product production, keep effective for a long time, can be directly added for use, or can be directly used as a coating material to form a film.

The invention relates to a sterilization additive, which comprises the following components: 30-40 wt% (30-40 wt%) of ethanol extract of dandelion, 20-30 wt% of ethanol extract of schisandra chinensis, 10-20 wt% of composite silver ion colloidal solution, 4-8 wt% of quaternary ammonium salt, 5-10 wt% of phosphate, 0.1-2 wt% of nano titanium dioxide powder, and 0.5-2 wt% of isothiazolinone or benzisothiazolinone or mixture of the two.

The preparation method of the sterilizing and disinfecting additive comprises the following steps:

1) adding 30-40 wt% of ethanol extract of dandelion and 20-30 wt% of ethanol extract of schisandra chinensis into a reaction kettle, and stirring at low temperature for 15min to 1 h;

2) sequentially mixing 10-20 wt% of composite silver ion colloidal solution, 4-8 wt% of quaternary ammonium salt, 5-10 wt% of phosphate and 0.1-2 wt% of nano titanium dioxide powder, dispersing, uniformly stirring, and mixing for 15min-1 h;

3) uniformly mixing the mixture obtained in the step 2), adding the mixture into the reaction kettle obtained in the step 1), dispersing and mixing the mixture, heating the mixture to 50-55 ℃, keeping the temperature for 2 hours, stirring and mixing the mixture, and then cooling the mixture to 20 ℃;

4) adding 0.5-2 wt% of isothiazolinone or benzisothiazolinone or a mixture of the two to the product of step 3); mixing uniformly, and performing closed low-temperature ultrasonic mixing reaction for 20min-1.5 h;

5) then the temperature is reduced, and the sterilizing and disinfecting additive product is obtained.

The invention relates to a sterilization and disinfection liquid medicine which comprises the following components: the invention relates to a sterilization and disinfection additive which is 5-15 wt%, self-crosslinking polyacrylate emulsion which is 30-50 wt%, nano silicon dioxide ethanol dispersion which is 7-15 wt%, dispersant which is 0.1-1 wt%, wetting agent which is 0.1-1 wt%, curing agent which is 0.1-2 wt%, silane coupling agent which is 10-20 wt%, adhesion promoter which is 10-20 wt% and film forming auxiliary agent which is 3-8 wt%.

The preparation process of the sterilizing and disinfecting liquid medicine comprises the following steps: the following components are added into the 5-15 wt% of the sterilizing and disinfecting additive of the invention by weight ratio: 7-15 wt% of nano silicon dioxide ethanol dispersion, 10-20 wt% of silane coupling agent, 30-50 wt% of self-crosslinking polyacrylate emulsion, 0.1-1 wt% of dispersing agent, 0.1-1 wt% of wetting agent, 0.1-2 wt% of curing agent, 10-20 wt% of adhesion promoter and 3-8 wt% of film-forming assistant, and the components are uniformly mixed and stirred to prepare the sterilization and disinfection liquid medicine.

Further, the dispersant can be produced by Keying chemistry and has a formula of KYC-9366C (molecular formula of C)₂₁H₁₄Na₂O₆Si₂) Or other dispersing agents.

The wetting agent comprises a wetting agent (main component: alkyl polyoxyethylene ether) which is produced by Beijing Maier chemical technology Limited and has the model number of HY-6170 or other wetting agents.

The silane coupling agent comprises KH-560 (molecular formula is C)₉H₂₀O₅Si, gamma- (2, 3-glycidoxy) propyltrimethoxysilane) or others.

The adhesion promoter includes EasyTech GT-2000 adhesion promoter manufactured by Shanghai Sanger chemical Co., Ltd or others.

The curing agent includes polyisocyanate or others.

The coalescing agents include ethylene glycol phenyl Ether (EPH) or others.

The adhesion promoter has the function that a protective layer of 1-5 microns can be formed on the surface of an object to be sprayed after the sterilization and disinfection liquid medicine is sprayed, and the protective layer has adhesion and wear resistance, so that the durable sterilization and disinfection effect is kept.

The dandelion ethanol extract and the schisandra ethanol extract in the formula have antibacterial and antiviral effects, and have inhibiting effects on staphylococcus aureus, hemolytic streptococcus, pneumococcus, pseudomonas aeruginosa, denatured bacillus, catacoccus, tubercle bacillus, influenza virus and various dermatophytes, the antiviral capability of the dandelion ethanol extract and the schisandra ethanol extract is improved by adding a nano titanium dioxide photocatalyst and the synergistic effect of silver ion components, so that the inactivation effect on various viruses is achieved, and meanwhile, isothiazolinone or/and benzisothiazolinone are added to keep the long-term sterilization and disinfection functions of the plant extracts.