阅读说明：本技术 一种具有抗蓝光功效修护眼霜及其制备方法 (Repair eye cream with blue light resisting effect and preparation method thereof ) 是由 夏有章 周道年 李名家 孙金龙 周丽 张卫平 于 2020-06-08 设计创作，主要内容包括：本发明提出了一种具有抗蓝光功效修护眼霜及其制备方法,所述抗蓝光功效修护眼霜包括功效组分、甘油、丁二醇、EDTA二钠、牛油果树果脂、鲸蜡硬脂醇、肉豆蔻酸异丙酯、双-PEG-18甲基醚二甲基硅烷、新戊二醇二辛酸酯、DC9040硅弹体、MONTANOV68乳化剂、SEPINOVEMT10增稠剂、SIMULSOL165乳化剂和去离子水,其中功效组分包括叶黄素、二裂酵母发酵产物溶孢物、乙酰基六肽-8、乙酰基四肽-5、棕榈酰五肽-4、可可籽提取物、烟酰胺、积雪草提取物、冰片、碳酸锌氢氧化物、琥珀粉、珍珠粉、硼砂、生育酚乙酸酯、葡糖基橙皮苷、尿囊素和富勒烯。本发明的具有抗蓝光功效修护眼霜,不仅具有抵御蓝光侵害,又具有修护功效,应用前景良好。(The invention provides a repair eye cream with an anti-blue-light effect and a preparation method thereof, wherein the repair eye cream with the anti-blue-light effect comprises an effect component, glycerin, butanediol, EDTA disodium, shea butter, cetostearyl alcohol, isopropyl myristate, bis-PEG-18 methyl ether dimethylsilane, neopentyl glycol dicaprylate, DC9040 silicon elastomer, MONTANOV68 emulsifier, SEPINOVEMT10 thickener, SIMULSOL165 emulsifier and deionized water, wherein the effect component comprises lutein, a yeast bifida fermentation product lysate, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, a cocoa seed extract, nicotinamide, a centella asiatica extract, borneol, zinc carbonate hydroxide, amber powder, pearl powder, borax, tocopheryl acetate, glucosyl hesperidin, allantoin and fullerene. The repair eye cream with the blue light resisting effect has the blue light resisting function, the repair effect and a good application prospect.)

1. The repair eye cream with the blue light resisting effect is characterized by comprising effective components, glycerin, butanediol, EDTA disodium, shea butter, cetostearyl alcohol, isopropyl myristate, bis-PEG-18 methyl ether dimethylsilane, neopentyl glycol dicaprylate, DC9040 silicon elastomer, MONTANOV68 emulsifier, SEPINOVEMT10 thickener, SIMULSOL165 emulsifier and deionized water.

2. The repair eye cream with anti-blue light effect of claim 1 wherein the effect component comprises: lutein, schizosaccharomyces cerevisiae fermentation product lysate, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, cacao seed extract, nicotinamide, centella asiatica extract, borneol, zinc carbonate hydroxide, amber powder, pearl powder, borax, tocopheryl acetate, glucosyl hesperidin, allantoin and fullerene.

3. The repair eye cream with the blue light resisting effect as claimed in claim 2, wherein the components are in parts by weight:

4. the repair eye cream with anti-blue light effect of claim 3, further comprising 1-10 parts of a stimulus-suppressing factor.

5. The repair eye cream with anti-blue light effect of claim 3, further comprising 1-10 parts of anti-allergic antipruritic.

6. The repair eye cream with anti-blue light effect of claim 3, further comprising 1-10 parts of an eye circumference pre-formulation.

7. The repair eye cream having anti-blue light effect of claim 3, further comprising 0.05-0.5 parts of a preservative and 0.15 parts of a perfume.

8. The method for preparing the eye cream with the blue light resisting effect as claimed in any one of claims 1 to 7, which is characterized by comprising the following steps:

heating allantoin, a stimulation inhibition factor, an anti-allergy antipruritic agent, glucosyl hesperidin, bis-PEG-18 methyl ether dimethylsilane, EDTA disodium and deionized water to 75-85 ℃, and preserving heat for 5-30 minutes to obtain a mixture phase A;

step two, mixing and heating shea butter, neopentyl glycol dicaprylate/dicaprate, MONTANOV68 emulsifier, cetostearyl alcohol, SIMULSOL165 emulsifier, isopropyl myristate, DC9040 silicon elastomer, tocopherol acetate and lutein to 75-85 ℃, and preserving heat for 5-30 minutes to obtain a mixture B phase;

step three, respectively crushing the amber powder, the pearl powder and the borax, sieving the mixture by a sieve of 100 meshes, mixing the mixture with zinc carbonate hydroxide, grinding the mixture, sieving the mixture by a sieve of 160 meshes, carrying out airflow crushing on the mixed medicinal powder to 200 meshes, and uniformly dispersing the mixed medicinal powder by glycerol at normal temperature to obtain a mixture C phase;

dispersing the SEPINOVEMT10 thickening agent uniformly with butanediol at normal temperature to obtain a mixture D phase;

dissolving borneol with butanediol at normal temperature to obtain a mixture E phase;

sixthly, dissolving the schizolysis product of the yeast for secondary fission, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, cocoa seed extract, nicotinamide, centella asiatica extract, fullerene and the eye circumference pre-mixture with the balance of deionized water at normal temperature to obtain a mixture F phase;

step seven, adding the mixture B phase after heat preservation into the mixture A phase, simultaneously adding the uniformly dispersed C phase, keeping the temperature at 75-85 ℃, vacuumizing, keeping high-speed homogenization and stirring for 5-30 minutes to obtain a first mixed phase;

step eight, adding the uniformly dispersed mixture phase D into the first mixed phase in a gathering manner, keeping the temperature at 75-85 ℃, vacuumizing, keeping high-speed homogenization, stirring for 5-30 minutes, stopping homogenization, keeping stirring and cooling to obtain a second mixed phase;

step nine, cooling the second mixed phase to 45-55 ℃, sequentially adding the uniformly mixed phase E and phase F, and keeping high-speed homogenization for 1-30 minutes to obtain a third mixed phase;

step ten, cooling the third mixed phase to 35-45 ℃, adding the preservative, the pH regulator and the essence, and stirring for 10-30 minutes to obtain the repair eye cream with the blue light resistance effect.

9. The method for preparing eye cream with anti-blue light effect according to claim 8, wherein the pH regulator is citric acid or aminomethyl propanol.

10. The process for preparing an eye cream with anti-blue light effect according to claim 8, wherein in the tenth step, a pH regulator is added to adjust the pH of the third mixed phase to 5.5-7.5.

Technical Field

The invention relates to the technical field of skin care products, in particular to a repair eye cream with an anti-blue-light effect and a preparation method thereof.

Background

The blue light is high-energy visible light with the wavelength of 400-500nm, the wavelength of the high-energy visible light is close to ultraviolet, the wavelength of the high-energy visible light is the shortest, 90% of the blue light which is contacted by people in daily life is from a natural light source, 10% of the blue light is from an artificial light source, the blue light intensity of electronic equipment can reach 80% of the sunlight, and obviously, the blue light is exposed to the blue light every day whether indoors or outdoors.

Blue light penetrates deeper into the skin than ultraviolet light, and can penetrate through the epidermis layer and the dermis layer and reach subcutaneous tissues, so that the blue light has the capacity of damaging all skin layers, and the mechanism of the blue light mainly comprises the following mechanisms: damage DNA and induce oxidative stress; weakening the epidermal barrier; damage to carbonylated proteins and lipids; inducing hyperpigmentation; damage to the extracellular matrix thereby accelerating aging; some studies have shown that overexposure to blue light results in protein aggregation in skin cells, exacerbating free radical production, causing cell damage and delaying repair.

Skin care products related to blue light resistance rarely appear on the market at present, and the blue light resistance mode of the existing skin care products mainly improves the physiological barrier of the horny layer by reducing the content of free radicals of the skin, and the problem that the skin is damaged due to the blue light cannot be solved in principle.

Disclosure of Invention

In view of the above, the invention provides a repair eye cream with an all-round blue light resisting effect and a preparation method thereof.

The technical scheme of the invention is realized as follows: the invention provides a repair eye cream with an anti-blue-light effect, which comprises an effect component, glycerin, butanediol, EDTA disodium, shea butter, cetostearyl alcohol, isopropyl myristate, bis-PEG-18 methyl ether dimethylsilane, neopentyl glycol dicaprylate, DC9040 silicon elastomer, MONTANOV68 emulsifier, SEPINOVEMT10 thickener, SIMULSOL165 emulsifier and deionized water.

On the basis of the technical scheme, preferably, the efficacy components comprise: lutein, schizosaccharomyces cerevisiae fermentation product lysate, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, cacao seed extract, nicotinamide, centella asiatica extract, borneol, zinc carbonate hydroxide, amber powder, pearl powder, borax, tocopheryl acetate, glucosyl hesperidin, allantoin and fullerene.

On the basis of the technical scheme, preferably, the weight parts of the components are as follows:

on the basis of the technical scheme, 1-10 parts of stimulation inhibition factors are preferably further included.

More preferably, the medicine also comprises 1 to 10 parts of anti-allergic antipruritic.

On the basis of the technical scheme, 1-10 parts of an eye circumference pre-blending agent is preferably further included.

On the basis of the technical scheme, the preservative preferably also comprises 0.05-5 parts of preservative and 0.15 part of essence.

On the basis of the technical scheme, preferably, the DC9040 silicon elastomer is a cyclopentadimethylsiloxane/polydimethylsiloxane cross-linked polymer, and the proportion of the cyclopentadimethylsiloxane to the polydimethylsiloxane is 70 wt%: 30 wt%.

On the basis of the technical scheme, preferably, the MONTANOV68 is a mixture of cetearyl alcohol and cetearyl glucoside, and the proportion of the cetearyl alcohol and the cetearyl glucoside is 80 wt%: 20 wt%.

On the basis of the technical scheme, preferably, the SEPINOV EMT10 is a mixture of hydroxyethyl acrylate, acryloyl dimethyl taurate copolymer, polysorbate-60, sorbitan isostearate and water, and the content ratio of the hydroxyethyl acrylate, the acryloyl dimethyl taurate copolymer, the polysorbate-60, the sorbitan isostearate and the water is 85 wt%: 5.5 wt%: 5.5 wt%: 4 wt%.

On the basis of the technical scheme, preferably, the SIMULSOL165 emulsifier is a mixture of glycerol stearate and PEG-100 stearate, and the content ratio of the glycerol stearate to the PEG-100 stearate is 50 wt%: 50 wt%.

On the basis of the technical scheme, preferably, the preservative is one of methyl hydroxybenzoate, propyl hydroxybenzoate and MicrocarePHDG.

The present invention uses lutein, which is a carotenoid, as a raw material, has excellent antioxidant activity and can filter high-energy blue light harmful to cells. The absorption spectrum characteristic band is between 400-500nm, and the absorption spectrum characteristic band just falls into a blue light region, and has a certain effect on blocking blue light. Meanwhile, the lutein can also effectively delay the degradation of skin elastin and collagen, so as to achieve the purpose of increasing skin elasticity.

The yeast lysate from the yeast fermentation is used as a raw material because severe UV or blue light irradiation causes irreparable cells in the skin, resulting in DNA double strand breaks. Micronucleus number is a measure of irreparable DNA damage. Under blue light pressure, a certain content of the secondary fission yeast fermentation product lysate can reduce the micronucleus formation rate. A biotechnically obtained split yeast fermentation lysate comprising metabolites, cytoplasmic components, cell wall components and polysaccharide complexes. Research shows that the lysate of the yeast fermentation product of the second split can stimulate a DNA moistening repair mechanism after ultraviolet or blue light irradiation, prevent the formation of double-strand breaks (micronuclei), effectively protect skin, keep the skin active, reduce the risk of chronic photodamage and resist the immunosuppression effect induced by ultraviolet or blue light.

Further, the present invention uses niacinamide and tocopheryl acetate. Nicotinamide (vitamin B3) in combination with tocopheryl acetate (vitamin E) protects against the production of reactive oxygen species ROS in the epidermis. Meanwhile, the niacinamide can relieve and prevent dark skin color, yellowing and vegetable color of the skin in the early aging process. Repairing damaged stratum corneum lipid barrier and improving skin resistance. Also has effects of deep water locking and moisturizing. The tocopherol acetate vitamin E has strong reducibility and can be used as an antioxidant. Can be used as antioxidant in vivo, and can eliminate free radicals in vivo and reduce the damage of ultraviolet rays to human body.

Furthermore, the cocoa seed extract, which is rich in molecular peptides, saccharides and polyphenols, can maintain the content of opsin photoreceptors under the pressure of blue light, reduce the content of active oxygen, promote the generation of more type I collagen and fibrillar protein-1, and remarkably improve the shape and length of the elastin fiber under UVB and blue light. Meanwhile, the content of Syndecano-4 can be obviously increased, which is very important for repairing the epidermis. It also reduces visible wrinkles and makes the skin surface smoother.

The glucosyl hesperidin in the raw materials has bioflavonoid with high solubility and stability, promotes penetrant, stimulates blood flow and blood circulation of skin, gives warm skin feel to the skin, effectively increases absorption and local metabolism of effective components, and relieves black eye circles, eye edema and tiredness.

The invention uses the centella extract in the raw materials, can effectively promote the tissue repair after skin injury, and particularly has important effect on promoting the anabolism of collagen. Fullerene has strong oxidation resistance, and has skin whitening and wrinkle resisting effects.

The acetyl tetrapeptide-5 in the raw material is used, so that microcirculation can be improved, liquid excretion can be promoted, water is inhibited from leaking into tissues from blood vessels, glycosylation is prevented, edema type eye bags can be effectively solved, and black eye circles can be improved; palmitoyl pentapeptide-4 can stimulate the synthesis of collagen and sucrose amino group hyaluronic acid, has long-acting anti-wrinkle and anti-aging effects, improves true wrinkles and black eye circles, can effectively improve aged sagging type eye bags, and improves black eye circles; acetyl tetrapeptide-5 has the effect of botulinum toxin, promotes the atrophy of hypertrophic eye muscles and effectively improves the muscular pouch. The synergistic effect of multiple active peptides can effectively and comprehensively improve under-eye puffiness and black eye circles.

The allantoin in the raw materials used in the invention has the effects of moistening skin and repairing skin injury, can promote cell growth and accelerate wound healing, has the physiological effect of softening a keratin layer, has good effect on repairing skin sunburn, and also has good moisture retention property.

The invention also provides a preparation method of the repair eye cream with the blue light resisting effect, which comprises the following steps:

heating allantoin, a stimulation inhibition factor, an anti-allergy antipruritic agent, glucosyl hesperidin, bis-PEG-18 methyl ether dimethylsilane, EDTA disodium and deionized water to 75-85 ℃, and preserving heat for 5-30 minutes to obtain a mixture phase A;

step two, mixing and heating shea butter, neopentyl glycol dicaprylate/dicaprate, MONTANOV68 emulsifier, cetostearyl alcohol, SIMULSOL165 emulsifier, isopropyl myristate, DC9040 silicon elastomer, tocopherol acetate and lutein to 75-85 ℃, and preserving heat for 5-30 minutes to obtain a mixture B phase;

step three, respectively crushing the amber powder, the pearl powder and the borax, sieving the mixture by a sieve of 100 meshes, mixing the mixture with zinc carbonate hydroxide, grinding the mixture, sieving the mixture by a sieve of 160 meshes, carrying out airflow crushing on the mixed medicinal powder to 200 meshes, and uniformly dispersing the mixed medicinal powder by glycerol at normal temperature to obtain a mixture C phase;

dispersing the SEPINOVEMT10 thickening agent uniformly with butanediol at normal temperature to obtain a mixture D phase;

dissolving borneol with butanediol at normal temperature to obtain a mixture E phase;

sixthly, dissolving the schizolysis product of the yeast for secondary fission, acetyl hexapeptide-8, acetyl tetrapeptide-5, palmitoyl pentapeptide-4, cocoa seed extract, nicotinamide, centella asiatica extract, fullerene and the eye circumference pre-mixture with the balance of deionized water at normal temperature to obtain a mixture F phase;

step seven, adding the mixture B phase after heat preservation into the mixture A phase, simultaneously adding the uniformly dispersed C phase, keeping the temperature at 75-85 ℃, vacuumizing, keeping high-speed homogenization and stirring for 5-30 minutes to obtain a first mixed phase;

step eight, adding the uniformly dispersed mixture phase D into the first mixed phase in a gathering manner, keeping the temperature at 75-85 ℃, vacuumizing, keeping high-speed homogenization, stirring for 5-30 minutes, stopping homogenization, keeping stirring and cooling to obtain a second mixed phase;

step nine, cooling the second mixed phase to 45-55 ℃, sequentially adding the uniformly mixed phase E and phase F, and keeping high-speed homogenization for 1-30 minutes to obtain a third mixed phase;

step ten, cooling the third mixed phase to 35-45 ℃, adding the preservative, the pH regulator and the essence, and stirring for 10-30 minutes to obtain the repair eye cream with the blue light resistance effect.

On the basis of the above technical scheme, preferably, the pH regulator is citric acid or aminomethyl propanol.

On the basis of the above technical scheme, preferably, in the tenth step, a pH regulator is added to adjust the pH of the third mixed phase to 5.5-7.5.

Compared with the prior art, the repair eye cream with the blue light resisting effect and the preparation method thereof have the following advantages

Has the advantages that:

compared with the prior art, the invention can resist blue light invasion more safely, more comprehensively and more deeply, and can effectively repair delicate skin around eyes, relieve and improve blood microcirculation around eyes, effectively fade fine lines, delay skin aging, improve black eye circles and eliminate sequelae of eye bags and the like after staying up at night.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

The amounts of the eye cream raw materials having anti-blue light effects of examples 1 to 7 of the present invention and the eye cream raw materials of the comparative example are shown in the following table: