阅读说明：本技术 一种抗菌保湿面膜 (Antibacterial moisturizing mask ) 是由 不公告发明人 于 2020-05-14 设计创作，主要内容包括：本发明公开了一种抗菌保湿面膜,包括抗菌保湿乳液和无纺布面膜纸,将抗菌保湿乳液浸透无纺布面膜纸后,经杀菌处理后封装得到,该抗菌保湿乳液,包括以下重量份的原料：15-20份甘油、1-3份PEG-100硬脂酸酯、2-4份鲸蜡硬脂醇、0.5-1份棕榈酸乙基己酯、2-5份聚二甲基硅氧烷、1-4份透明质酸、3-7份黄原胶、0.2-0.5份抗菌剂、2-5份维生素E、3-7份胶原蛋白、35-50份丙二醇、200份去离子水；组成配方合理,制备方法简单,易于放大化生产,制备的面膜易吸收,质地均匀,保湿性良好,且具有一定的美白效果。(The invention discloses an antibacterial moisturizing mask which comprises antibacterial moisturizing emulsion and non-woven fabric mask paper, wherein the antibacterial moisturizing emulsion is obtained by soaking the non-woven fabric mask paper with the antibacterial moisturizing emulsion, sterilizing and packaging, and comprises the following raw materials in parts by weight: 15-20 parts of glycerol, 1-3 parts of PEG-100 stearate, 2-4 parts of cetostearyl alcohol, 0.5-1 part of ethylhexyl palmitate, 2-5 parts of polydimethylsiloxane, 1-4 parts of hyaluronic acid, 3-7 parts of xanthan gum, 0.2-0.5 part of an antibacterial agent, 2-5 parts of vitamin E, 3-7 parts of collagen, 35-50 parts of propylene glycol and 200 parts of deionized water; the facial mask has the advantages of reasonable composition formula, simple preparation method, easy scale-up production, easy absorption, uniform texture, good moisture retention and certain whitening effect.)

1. The antibacterial moisturizing mask comprises an antibacterial moisturizing emulsion and non-woven fabric mask paper, and is obtained by packaging after the antibacterial moisturizing emulsion is soaked in the non-woven fabric mask paper and is subjected to sterilization treatment, and the antibacterial moisturizing mask is characterized in that: the antibacterial moisturizing emulsion comprises the following raw materials in parts by weight: 15-20 parts of glycerol, 1-3 parts of PEG-100 stearate, 2-4 parts of cetostearyl alcohol, 0.5-1 part of ethylhexyl palmitate, 2-5 parts of polydimethylsiloxane, 1-4 parts of hyaluronic acid, 3-7 parts of xanthan gum, 0.2-0.5 part of an antibacterial agent, 2-5 parts of vitamin E, 3-7 parts of collagen, 35-50 parts of propylene glycol and 200 parts of deionized water.

2. The antibacterial moisture mask according to claim 1, wherein: the preparation method of the antibacterial moisturizing emulsion specifically comprises the following steps:

preparation of phase A: adding glycerol, hyaluronic acid, vitamin E, collagen, propylene glycol and deionized water into a flask, then putting the flask into a water bath kettle, and uniformly stirring for later use;

preparation of phase B: adding PEG-100 stearate, stearyl alcohol wax, ethylhexyl palmitate, polydimethylsiloxane, xanthan gum and an antibacterial agent into another flask, then putting the flask into a water bath kettle, and uniformly stirring for later use;

and then slowly adding the uniformly mixed phase B into the phase A while stirring the phase A, keeping the temperature and stirring for 1h after the phase A is added, and finally transferring the uniformly mixed emulsion into a homogenizer for homogenizing and emulsifying for 3-5min to obtain the antibacterial moisturizing emulsion.

3. The antibacterial moisture mask according to claim 2, wherein: the temperature of the water bath of the phase A and the phase B is 70-75 ℃.

4. The antibacterial moisture mask according to claim 1, wherein: the preparation method of the antibacterial agent comprises the following steps:

adding 10mml of phloroglucinol, 11-12mmol of 3, 5-dimethylphenylacetic acid and a catalyst into a reaction kettle, then adding 200-250ml of DMF (dimethyl formamide) solvent, stirring for dissolving, introducing nitrogen for protection, heating to 65-70 ℃, preserving heat, stirring for reacting for 2-2.5h, rotationally evaporating to remove the solvent, cooling to room temperature, adding 100-120ml of 10 mass percent hydrochloric acid aqueous solution, stirring for 15-20min, performing suction filtration, washing a filtrate by using deionized water until the pH value is 6.4-7.0, and then performing recrystallization by using 45 mass percent ethanol aqueous solution to obtain a compound N;

secondly, adding a compound N, a catalyst and 200ml of 150-5-inch solvent DMF (dimethyl formamide) into a reaction kettle, stirring for dissolving, introducing nitrogen for protection, dropwise adding 4-5ml of a cyclization agent in the nitrogen atmosphere, heating to 70-75 ℃ while stirring after the addition is finished, preserving heat, stirring for reaction for 2-3h, adding 200ml of deionized water after the reaction is finished, stirring for 5-10min, performing suction filtration, dissolving a filtrate by using a hot 70-75% ethanol solution at 60-65 ℃, filtering while the filtrate is hot, naturally cooling the filtrate to room temperature, standing in a refrigerator at 0-5 ℃ for 3-4h, filtering, and drying to obtain an antibacterial agent M;

the antimicrobial agent M has the following reaction formula:

。

5. the antibacterial moisture mask according to claim 4, wherein: the catalyst in the first step is AlCl₃The addition amount of the catalyst is 1.5-3 mmol.

6. The antibacterial moisture mask according to claim 4, wherein: in the second step, the catalyst is sodium acetate, and the adding amount of the catalyst is 5-8 g.

7. The antibacterial moisture mask according to claim 4, wherein: the cyclization agent in the second step is DMF-phosphorus oxychloride.

8. The antibacterial moisture mask according to claim 7, wherein: the preparation method of the cyclization agent comprises the following steps: adding 4ml of DMF into a beaker, dropwise adding 3-4ml of phosphorus oxychloride while stirring, after dropwise adding, heating to 40-45 ℃ while stirring, and keeping the temperature and stirring for 25-30min to obtain the DMF-phosphorus oxychloride cyclization agent.

Technical Field

The invention belongs to the technical field of cosmetics, and particularly relates to an antibacterial moisturizing mask.

Background

Facial masks, one category of skin care products. The most basic and important purpose is to make up and remove makeup and wash the face still insufficient cleaning work, and realize other maintenance functions such as moisturizing, whitening, anti-aging, grease balancing and the like by matching with other essential components on the basis; the facial mask essence contains more nutrient components, and a preservative is required to be additionally added to inhibit the growth and reproduction of microorganisms, so that the cosmetic has stable property, is not easy to deteriorate after being uncovered and is prolonged in storage time. Common cosmetic preservatives include benzyl alcohol, benzoic acid, salicylic acid, boric acid, sorbic acid, other alcohols, aldehydes and other substances, and the cosmetic preservatives have good antiseptic and antibacterial effects, but do not have a skin care effect and can increase the probability of allergy to sensitive skin, so that the development of the antibacterial agent with the care effect is of great significance.

Disclosure of Invention

The invention aims to provide an antibacterial moisturizing mask which comprises antibacterial moisturizing emulsion and non-woven fabric mask paper, wherein the antibacterial moisturizing emulsion is obtained by soaking the non-woven fabric mask paper in the antibacterial moisturizing emulsion, sterilizing and packaging; the facial mask has the advantages of reasonable composition formula, simple preparation method, easy scale-up production, easy absorption, uniform texture, good moisture retention and certain whitening effect.

The purpose of the invention can be realized by the following technical scheme:

the antibacterial moisturizing facial mask comprises an antibacterial moisturizing emulsion and non-woven fabric facial mask paper, wherein the antibacterial moisturizing emulsion is obtained by soaking the non-woven fabric facial mask paper with the antibacterial moisturizing emulsion, sterilizing and packaging, and the antibacterial moisturizing emulsion comprises the following raw materials in parts by weight: 15-20 parts of glycerol, 1-3 parts of PEG-100 stearate, 2-4 parts of cetostearyl alcohol, 0.5-1 part of ethylhexyl palmitate, 2-5 parts of polydimethylsiloxane, 1-4 parts of hyaluronic acid, 3-7 parts of xanthan gum, 0.2-0.5 part of an antibacterial agent, 2-5 parts of vitamin E, 3-7 parts of collagen, 35-50 parts of propylene glycol and 200 parts of deionized water.

Further, the preparation method of the antibacterial moisturizing emulsion specifically comprises the following steps:

preparation of phase A: adding glycerol, hyaluronic acid, vitamin E, collagen, propylene glycol and deionized water into a flask, then putting the flask into a water bath kettle, and uniformly stirring for later use;

preparation of phase B: adding PEG-100 stearate, stearyl alcohol wax, ethylhexyl palmitate, polydimethylsiloxane, xanthan gum and an antibacterial agent into another flask, then putting the flask into a water bath kettle, and uniformly stirring for later use;

and then slowly adding the uniformly mixed phase B into the phase A while stirring the phase A, keeping the temperature and stirring for 1h after the phase A is added, and finally transferring the uniformly mixed emulsion into a homogenizer for homogenizing and emulsifying for 3-5min to obtain the antibacterial moisturizing emulsion.

Further, the temperature of the A phase water bath kettle and the B phase water bath kettle is 70-75 ℃.

Further, the preparation method of the antibacterial agent comprises the following steps:

adding 10mml of phloroglucinol, 11-12mmol of 3, 5-dimethyl phenylacetic acid and a catalyst into a reaction kettle, then adding 200-250ml of DMF (dimethyl formamide) solvent, stirring and dissolving, introducing nitrogen for protection, heating to 65-70 ℃, preserving heat, stirring and reacting for 2-2.5h, performing rotary evaporation to remove the solvent, cooling to room temperature, adding 100-120ml of 10 mass percent hydrochloric acid aqueous solution, stirring for 15-20min, performing suction filtration, washing a filtrate by using deionized water until the pH value is 6.4-7.0, and then performing recrystallization by using 45 mass percent ethanol aqueous solution to obtain a compound N;

secondly, adding a compound N, a catalyst and 200ml of 150-5-inch solvent DMF (dimethyl formamide) into a reaction kettle, stirring for dissolving, introducing nitrogen for protection, dropwise adding 4-5ml of cyclizing agent into the reaction kettle in the nitrogen atmosphere, heating to 70-75 ℃ while stirring after the addition is finished, preserving heat, stirring for reacting for 2-3h, adding 200ml of deionized water after the reaction is finished, stirring for 5-10min, performing suction filtration, dissolving a filtrate by using a hot 70-75% ethanol solution at 60-65 ℃, filtering while the filtrate is hot, naturally cooling the filtrate to room temperature, standing in a refrigerator at 0-5 ℃ for 3-4h, filtering, and drying to obtain the antibacterial agent M;

the antimicrobial agent M has the following reaction formula:

further, the catalyst in the first step is AlCl₃The addition amount of the catalyst is 1.5-3 mmol.

Furthermore, the catalyst in the second step is sodium acetate, and the adding amount of the catalyst is 5-8 g.

Further, the cyclization agent in the second step is DMF-phosphorus oxychloride.

Further, the preparation method of the cyclization agent comprises the following steps: adding 4ml of DMF into a beaker, dropwise adding 3-4ml of phosphorus oxychloride while stirring, after dropwise adding, heating to 40-45 ℃ while stirring, and keeping the temperature and stirring for 25-30min to obtain the DMF-phosphorus oxychloride cyclization agent.

The invention has the beneficial effects that:

the invention provides an antibacterial moisturizing mask, which comprises antibacterial moisturizing emulsion and non-woven fabric mask paper, wherein the antibacterial moisturizing emulsion is obtained by soaking the non-woven fabric mask paper in the antibacterial moisturizing emulsion, sterilizing and packaging; the composition formula is reasonable, the preparation method is simple, the large-scale production is easy, the prepared mask is easy to absorb, uniform in texture and good in moisture retention, and has a certain whitening effect;

the prepared antibacterial agent takes phloroglucinol and 3, 5-dimethylphenyl acetic acid as raw materials and adopts AlCl as a catalyst₃Under the action of the sodium acetate catalyst and the cyclization agent, performing a Friedel-crafts acylation reaction to prepare a compound N, and then performing an intramolecular cyclization reaction on the compound N under the action of the sodium acetate catalyst and the cyclization agent to obtain an antibacterial agent M; the antibacterial agent M structure contains antibacterial functional group phenolic hydroxyl, has good sterilization and oxidation resistance effects, does not need to add an additional preservative, prolongs the shelf life of the mask, and can chelate metal ions such as iron ions or copper ions with carbonyl and phenolic hydroxyl on ortho-position in the antibacterial agent M structure(s) ((L is metal ion) to reduce the generation of oxygen free radicals, and the activity of tyrosinase can be inhibited by chelating copper ions to reduce the generation of melanin, thereby achieving the whitening effect.

Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used for describing the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without any creative effort.

FIG. 1 is a reaction scheme of the antibacterial agent of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.