阅读说明：本技术 一种治疗慢性乙肝的中药配方及其制作方法 (Traditional Chinese medicine formula for treating chronic hepatitis B and preparation method thereof ) 是由 梁平 李骞 于 2020-06-24 设计创作，主要内容包括：本发明涉及中药领域,一种治疗慢性乙肝的中药配方及其制作方法,药物组成以及重量配比为：柴胡5-30g,黄芩5-30g,枳实5-30g,油朴5-30g,川楝子5-30g,台乌5-30g,茵陈5-30g,板蓝根5-30g,虎杖5-30g,金钱草10-100g,夏枯草10-100g,半枝莲10-100g,白花蛇舌草10-100g；一种治疗慢性乙肝的中药的其制作方法,包括以下步骤：优点在于：由上述原料药物配伍组成的乙肝药,具有滋阴疏肝、健脾和胃、理气止痛、益气解毒、促成抗体生成,保护肝脏的作用。能有效的的治疗乙肝及其伴发的躯体化症状。(The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula for treating chronic hepatitis B and a preparation method thereof, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: 5-30g of radix bupleuri, 5-30g of scutellaria baicalensis, 5-30g of immature bitter orange, 5-30g of magnolia obavata, 5-30g of szechwan chinaberry fruit, 5-30g of radix aconiti agrestis, 5-30g of oriental wormwood, 5-30g of isatis root, 5-30g of polygonum cuspidatum, 10-100g of desmodium, 10-100g of selfheal, 10-100g of barbed skullcap herb and 10-100g of oldenlandia diffusa; a preparation method of a traditional Chinese medicine for treating chronic hepatitis B comprises the following steps: has the advantages that: the medicine for treating hepatitis B, which is prepared by the compatibility of the raw material medicines, has the functions of nourishing yin, soothing the liver, strengthening the spleen and stomach, regulating qi, relieving pain, tonifying qi, detoxifying, promoting antibody generation and protecting the liver. Can effectively treat hepatitis B and the concomitant somatization symptom thereof.)

1. The traditional Chinese medicine formula for treating chronic hepatitis B is characterized by comprising the following components in parts by weight: 5-30g of radix bupleuri, 5-30g of scutellaria baicalensis, 5-30g of immature bitter orange, 5-30g of magnolia obavata, 5-30g of szechwan chinaberry fruit, 5-30g of radix aconiti agrestis, 5-30g of oriental wormwood, 5-30g of isatis root, 5-30g of polygonum cuspidatum, 10-100g of desmodium, 10-100g of selfheal, 10-100g of barbed skullcap herb and 10-100g of oldenlandia diffusa.

2. The traditional Chinese medicine formula for treating chronic hepatitis B according to claim 1, which is characterized by comprising the following components in parts by weight: 5g of radix bupleuri, 5g of scutellaria baicalensis, 5g of immature bitter orange, 5g of magnolia officinalis, 5g of szechwan chinaberry fruit, 5g of radix linderae, 5g of oriental wormwood, 5g of isatis root, 50g of polygonum cuspidatum, 10g of desmodium, 10g of selfheal, 10g of scutellaria barbata and 10g of oldenlandia diffusa.

3. The traditional Chinese medicine formula for treating chronic hepatitis B according to claim 1, which is characterized by comprising the following components in parts by weight: 17g of radix bupleuri, 17g of scutellaria baicalensis, 17g of immature bitter orange, 17g of magnolia officinalis, 17g of szechwan chinaberry fruit, 17g of radix linderae, 17g of oriental wormwood, 17g of isatis root, 17g of polygonum cuspidatum, 55g of desmodium, 55g of selfheal, 55g of scutellaria barbata and 55g of oldenlandia diffusa.

4. The traditional Chinese medicine formula for treating chronic hepatitis B according to claim 1, which is characterized by comprising the following components in parts by weight: 30g of radix bupleuri, 30g of scutellaria baicalensis, 30g of immature bitter orange, 30g of magnolia officinalis, 30g of szechwan chinaberry fruit, 30g of radix linderae, 30g of oriental wormwood, 30g of isatis root, 30g of giant knotweed, 100g of desmodium, 100g of selfheal, 100g of barbed skullcap herb and 100g of oldenlandia diffusa.

5. The preparation method of the traditional Chinese medicine for treating chronic hepatitis B according to claim 1, characterized by comprising the following steps:

(1) mixing radix bupleuri, scutellaria baicalensis, immature bitter orange, magnolia officinalis, szechwan chinaberry fruit, radix aconiti agrestis, oriental wormwood, isatis root, polygonum cuspidatum, longhairy antenoron herb, selfheal, barbed skullcap herb and oldenlandia diffusa together according to the weight ratio, carrying out superfine grinding and grinding into powder;

(2) sterilizing the powder obtained in the step (1) by using an ultraviolet sterilization device;

(3) adding a proper amount of water into the powder obtained in the step (2), and kneading the powder into pills;

(4) drying the pills obtained in the step (3) at a low temperature;

(5) and (4) screening and packaging the pills obtained in the step (4).

Technical Field

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula for treating chronic hepatitis B and a preparation method thereof.

Background

Chronic hepatitis B (hepatitis B for short) refers to the clinical chronic hepatitis with positive hepatitis B virus detection, over half a year of disease course or indefinite disease date. Clinically, it is manifested as lassitude, aversion to food, nausea, abdominal distention, and pain in the liver. Liver is large, medium hardness, and slight tenderness. The serious disease may be accompanied by facial appearance of chronic liver disease, spider nevus, hepatomegaly, splenomegaly, and abnormal or persistent liver function. According to clinical manifestations, the disease is divided into mild, moderate and severe. The chronic hepatitis B carrying means that hepatitis B virus is detected to be positive, no chronic hepatitis symptom exists, serum ALT and AST have no abnormality after continuous follow-up for more than three times in one year, and liver histology examination is normal.

Therefore, how to find a medicine which can effectively treat acute and chronic hepatitis B is a problem which needs to be solved at present.

Disclosure of Invention

The invention aims to overcome the technical defects and provides a traditional Chinese medicine formula for treating chronic hepatitis B and a preparation method thereof.

In order to solve the technical problems, the technical scheme provided by the invention is a traditional Chinese medicine formula for treating chronic hepatitis B, and the traditional Chinese medicine formula comprises the following components in parts by weight: 5-30g of radix bupleuri, 5-30g of scutellaria baicalensis, 5-30g of immature bitter orange, 5-30g of magnolia obavata, 5-30g of szechwan chinaberry fruit, 5-30g of radix aconiti agrestis, 5-30g of oriental wormwood, 5-30g of isatis root, 5-30g of polygonum cuspidatum, 10-100g of desmodium, 10-100g of selfheal, 10-100g of barbed skullcap herb and 10-100g of oldenlandia diffusa.

The improvement comprises 5g of radix bupleuri, 5g of radix scutellariae, 5g of immature bitter orange, 5g of magnolia officinalis, 5g of szechwan chinaberry fruit, 5g of radix aconiti agrestis, 5g of oriental wormwood, 5g of radix isatidis, 50g of giant knotweed rhizome, 10g of desmodium, 10g of selfheal, 10g of herba scutellariae barbatae and 10g of oldenlandia diffusa.

For improvement, 17g of radix bupleuri, 17g of radix scutellariae, 17g of immature bitter orange, 17g of magnolia officinalis, 17g of szechwan chinaberry fruit, 17g of radix aconiti agrestis, 17g of oriental wormwood, 17g of radix isatidis, 17g of giant knotweed rhizome, 55g of desmodium, 55g of selfheal, 55g of herba scutellariae barbatae and 55g of oldenlandia diffusa.

As an improvement, 30g of radix bupleuri, 30g of radix scutellariae, 30g of immature bitter orange, 30g of magnolia officinalis, 30g of szechwan chinaberry fruit, 30g of radix linderae, 30g of oriental wormwood, 30g of radix isatidis, 30g of giant knotweed, 100g of desmodium, 100g of selfheal, 100g of barbed skullcap herb and 100g of oldenlandia diffusa.

A preparation method of a traditional Chinese medicine for treating chronic hepatitis B comprises the following steps: (1) mixing radix bupleuri, scutellaria baicalensis, immature bitter orange, magnolia officinalis, szechwan chinaberry fruit, radix aconiti agrestis, oriental wormwood, isatis root, polygonum cuspidatum, longhairy antenoron herb, selfheal, barbed skullcap herb and oldenlandia diffusa together according to the weight ratio, carrying out superfine grinding and grinding into powder;

(2) sterilizing the powder obtained in the step (1) by using an ultraviolet sterilization device;

(3) adding a proper amount of water into the powder obtained in the step (2), and kneading the powder into pills;

(4) drying the pills obtained in the step (3) at a low temperature;

(5) and (4) screening and packaging the pills obtained in the step (4).

Bupleurum root, the efficacy: harmonize exterior and interior, soothe liver, relieve depression, raise yang, lift sinking, allay fever and check malaria. The main treatment is as follows: can be used for treating common cold, fever, alternating chills and fever, distending pain in chest and hypochondrium, menoxenia, uterine prolapse, and proctoptosis.

Scutellaria baicalensis, efficacy: clear heat and dry dampness, purge fire and remove toxicity, stop bleeding, prevent abortion. The main treatment is as follows: can be used for treating damp-warm syndrome, summer-heat dampness, chest distress, emesis, dampness and heat distention, dysentery, jaundice, cough due to lung heat, hyperpyrexia, polydipsia, hematemesis, carbuncle, swelling, sore, and threatened abortion.

Immature bitter orange, efficacy: break qi and remove food retention, resolve phlegm and disperse distention and fullness. The main treatment is as follows: can be used for treating stagnation, abdominal distention, pain, dysentery, constipation, phlegm stagnation, qi stagnation, thoracic obstruction, and viscera prolapse.

Oil and plain, efficacy: dry dampness and resolve phlegm, descend qi and remove fullness. Can be used for treating damp stagnation, abdominal distention, emesis, diarrhea, dyspepsia, abdominal distention, constipation, phlegm retention, asthma, and cough.

Toosendan fruit, efficacy: to soothe the liver, release heat, promote qi circulation, alleviate pain and kill parasites. The main treatment is as follows: can be used for treating liver depression, pathogenic fire, distending pain of chest, hypochondrium, abdominal cavity, hernia pain, and abdominal pain due to parasitic infestation.

Taiwu, efficacy: promoting qi circulation to relieve pain, warming kidney to dispel cold, and can be used for treating cold accumulation and qi stagnation pain in chest and abdomen, pollakisuria, enuresis, menoxenia, dysmenorrhea, and abdominal pain due to cold in uterus. Radix Polygoni Multiflori Preparata is used for regulating and nourishing liver and kidney.

Herba artemisiae scopariae, the function: has effects of clearing away dampness and heat, promoting bile flow, and eliminating jaundice. The main treatment is as follows: can be used for treating jaundice, oliguria, damp warmth, summer dampness, eczema, and pruritus.

Isatis root, efficacy: clear heat and remove toxicity, cool blood and relieve sore throat. The main treatment is as follows: fever due to exogenous pathogens, early stage of epidemic febrile disease, swollen and sore throat, warm toxicity and macula, mumps, erysipelas, carbuncle, swelling and sore.

Giant knotweed rhizome, efficacy: promoting diuresis, removing jaundice, clearing heat, removing toxic substances, removing blood stasis, relieving pain, relieving cough, and eliminating phlegm. The main treatment is as follows: can be used for treating jaundice due to damp-heat pathogen, stranguria with turbid discharge, leukorrhagia, rheumatalgia, carbuncle, swelling, sore, scald due to water and fire, amenorrhea, abdominal mass, contusion injury, and cough due to lung heat.

Lysimachia christinae Hance, herba Lysimachiae Christinae, with functions and indications: induce diuresis to alleviate jaundice, induce diuresis to treat stranguria, remove toxicity and relieve swelling. Can be used for treating damp-heat jaundice, gallbladder distention, hypochondriac pain, stranguria with stone, stranguria with heat, difficulty and pain in urination, carbuncle, furuncle, and snake and insect bite.

Selfheal, medicinal property: pungent, bitter and cold. It enters liver and gallbladder meridians. Has the effects of clearing heat and purging fire, improving eyesight, resolving masses and relieving swelling. Barbat skullcap, for indication: has the effects of clearing away heat and toxic materials, promoting blood circulation, dispelling blood stasis, relieving swelling and pain, and preventing cancer; treating appendicitis, hepatitis, stomach ache, early hepatocarcinoma, lung cancer, cervical cancer, mastitis, etc.; it can be used for treating pain, furuncle, traumatic injury, and swelling and pain.

Oldenlandia diffusa, main treatment: cough and asthma due to lung heat; swollen and sore throat; intestinal abscess; furuncle, swelling, sore and ulcer; bite by poisonous snake; stranguria with heat manifested as painful urination; edema; dysentery; enteritis; jaundice due to damp-heat; it is good at treating various cancers.

Compared with the prior art, the invention has the advantages that: the medicine for treating hepatitis B, which is prepared by the compatibility of the raw material medicines, has the functions of nourishing yin, soothing the liver, strengthening the spleen and stomach, regulating qi, relieving pain, tonifying qi, detoxifying, promoting antibody generation and protecting the liver. Can effectively treat hepatitis B and the concomitant somatization symptom thereof.

Detailed Description

The following will explain the formula of the Chinese medicine for treating chronic hepatitis B and the preparation method thereof in further detail.

A traditional Chinese medicine formula for treating chronic hepatitis B comprises the following components in parts by weight: 5-30g of radix bupleuri, 5-30g of scutellaria baicalensis, 5-30g of immature bitter orange, 5-30g of magnolia obavata, 5-30g of szechwan chinaberry fruit, 5-30g of radix aconiti agrestis, 5-30g of oriental wormwood, 5-30g of isatis root, 5-30g of polygonum cuspidatum, 10-100g of desmodium, 10-100g of selfheal, 10-100g of barbed skullcap herb and 10-100g of oldenlandia diffusa.

A preparation method of a traditional Chinese medicine for treating chronic hepatitis B comprises the following steps: (1) mixing radix bupleuri, scutellaria baicalensis, immature bitter orange, magnolia officinalis, szechwan chinaberry fruit, radix aconiti agrestis, oriental wormwood, isatis root, polygonum cuspidatum, longhairy antenoron herb, selfheal, barbed skullcap herb and oldenlandia diffusa together according to the weight ratio, carrying out superfine grinding and grinding into powder;

(2) sterilizing the powder obtained in the step (1) by using an ultraviolet sterilization device;

(3) adding a proper amount of water into the powder obtained in the step (2), and kneading the powder into pills;

(4) drying the pills obtained in the step (3) at a low temperature;

(5) and (4) screening and packaging the pills obtained in the step (4).

Has the advantages that: the medicine for treating hepatitis B, which is prepared by the compatibility of the raw material medicines, has the functions of nourishing yin, soothing the liver, strengthening the spleen and stomach, regulating qi, relieving pain, tonifying qi, detoxifying, promoting antibody generation and protecting the liver. Can effectively treat hepatitis B and the concomitant somatization symptom thereof.