阅读说明：本技术 一种复配驱蚊精油、应用及驱蚊剂 (Compound mosquito-repelling essential oil, application and mosquito repellent ) 是由 王永红 高洪昌 吴华 张兴 于 2019-11-01 设计创作，主要内容包括：本文发明公开了一种复配驱蚊精油、应用及驱蚊剂,一种复配驱蚊精油,含有荆芥油和薄荷油,荆芥油和薄荷油的质量比为1～9:9～1。可选的,荆芥油和薄荷油的质量比为3～7:7～3。优选的,荆芥油和薄荷油的质量比为7:3。本发明在发现了荆芥油和薄荷油对蚊虫具有驱避活性的基础上,为了进一步提高驱蚊活性,同时解决植物精油易挥发的缺点,本发明利用荆芥油和薄荷油的混合物为驱蚊活性成分,在一定比例下进行复配,制备成驱蚊精油,将精油用于制备驱蚊剂的应用,最后得到驱蚊剂。(The invention discloses compound mosquito-repellent essential oil, application and a mosquito repellent agent, and the compound mosquito-repellent essential oil contains catnip oil and mint oil, wherein the mass ratio of the catnip oil to the mint oil is 1-9: 9-1. Optionally, the mass ratio of the catmint oil to the mint oil is 3-7: 7-3. Preferably, the mass ratio of the catmint oil to the mint oil is 7: 3. On the basis of finding that the catmint oil and the mint oil have mosquito repelling activity, in order to further improve the mosquito repelling activity and solve the problem that the plant essential oil is volatile, the invention utilizes the mixture of the catmint oil and the mint oil as mosquito repelling active ingredients, compounds the active ingredients at a certain proportion to prepare the mosquito repelling essential oil, and applies the essential oil to the preparation of the mosquito repelling agent to finally obtain the mosquito repelling agent.)

1. The compound mosquito-repellent essential oil is characterized by comprising catnip oil and mint oil, wherein the mass ratio of the catnip oil to the mint oil is 1-9: 9-1.

2. The compound mosquito-repellent essential oil according to claim 1, wherein the mass ratio of the schizonepeta oil to the mint oil is 3-7: 7-3.

3. The compound mosquito-repellent essential oil according to claim 1, wherein the mass ratio of the catmint oil to the mint oil is 7: 3.

4. The application of the compound mosquito-repellent essential oil of any one of claims 1 to 3 in preparing a mosquito repellent, wherein the mosquito repellent is mosquito repellent liquid, mosquito repellent incense, mosquito repellent paste, mosquito repellent ointment or other mosquito repellent products.

5. The mosquito repellent is characterized by being mosquito repellent ointment, wherein the active ingredients of the mosquito repellent ointment are catnip oil and mint oil, and the mass ratio of the catnip oil to the mint oil is 1-9: 9-1.

6. The mosquito repellent is characterized by being mosquito repellent ointment, wherein the active ingredients of the mosquito repellent ointment are catnip oil and mint oil, and the mass ratio of the catnip oil to the mint oil is 3-7: 7-3.

7. The mosquito repellent is characterized by being mosquito repellent ointment, wherein the active ingredients of the mosquito repellent ointment are catmint oil and mint oil, and the mass ratio of the catmint oil to the mint oil is 7: 3.

8. A mosquito repellent according to any one of claims 5 to 6, which is characterized by being prepared from the following raw materials in percentage by weight: 10-30% of nano material containing active ingredients, 2-10% of emulsifier, 16-24% of dispersant, 15-20% of lubricant and the balance of solvent, wherein the sum of the mass percentages of the raw materials is 100%;

the nano material is nano silicon dioxide, the particle size of the nano silicon dioxide is 80-150 nm, and the drug loading of the nano silicon dioxide is 142.39%.

9. A mosquito repellent according to claim 8, wherein the emulsifier is cetyl alcohol, the dispersant is one of glyceryl monostearate and liquid paraffin, the lubricant is glycerin, and the solvent is water.

10. The mosquito repellent according to claim 8, characterized in that the preparation method comprises the following steps:

s1: weighing the activated nano-silica material, adding a proper amount of liquid paraffin to completely disperse the nano-silica, and then adding the catnip oil and the peppermint oil according to the formula amount for adsorption to obtain the drug-loaded nano-silica;

s2: melting glyceryl monostearate, cetyl alcohol and paraffin according to the formula amount, and adding the drug-loaded nano-silica as an oil phase;

s3: uniformly mixing glycerol, tween-80 and water in a formula amount to obtain a water phase;

s4: adding the water phase into the oil phase to form viscous white liquid, and cooling to obtain the final product.

Technical Field

The invention belongs to the field of sanitary pest prevention and control, and particularly relates to compound mosquito-repellent essential oil, application and a mosquito repellent.

Background field of the invention

Catnip oil is extracted from schizonepeta spike, catnip (Schizonepetatenuifoliabriq.) is a dry overground part of schizonepeta herb of annual herb of Labiatae, also known as pseudosci, is slightly warm in nature and pungent in taste, belongs to lung and liver meridians, is used for treating various exterior syndromes, is a clinical common traditional Chinese medicine, and has a long medicine use history and obvious medicine effect (2015, one part of the Chinese pharmacopoeia 2015. 2015: 232-.

Peppermint oil is extracted from plant mint (Mentha happalycalxBriq.) which is a plant of Mentha of Labiatae, is one of the traditional Chinese medicines commonly used in China, and is an important spice plant. Herba Menthae has effects of dispelling pathogenic wind, clearing heat away, and removing toxic substance, and can be used for treating wind-heat type common cold, headache, conjunctival congestion, sore throat, toothache, etc.

The research results of using plant essential oil to repel mosquitoes show that most of plant essential oil has certain mosquito repelling effect on the mosquitoes, and the mosquito repelling effect has certain difference. The plant essential oil has the defect of short persistence due to the characteristic of strong volatility, and the plant essential oil is prepared into a corresponding mosquito repellent preparation by using a nano slow-release material, so that the persistence of the plant essential oil is improved. The research reports on the application of the plant essential oil to the mosquito repellent preparation are relatively few, and the plant essential oil serving as a plant source substance has wide development space when being used for preparing the mosquito repellent preparation due to the characteristics of small environmental pollution, difficult generation of drug resistance, safety to human health and the like.

Disclosure of Invention

On the basis of finding that the catmint oil and the mint oil have mosquito repelling activity, in order to further improve the mosquito repelling activity and solve the problem that the plant essential oil is volatile, the invention utilizes the mixture of the catmint oil and the mint oil as mosquito repelling active ingredients, compounds the active ingredients at a certain proportion to prepare the mosquito repelling essential oil, and applies the essential oil to the preparation of the mosquito repelling agent to finally obtain the mosquito repelling agent.

In order to achieve the purpose, the invention adopts the technical scheme that:

a compound mosquito repellent essential oil comprises catnip oil and mint oil, wherein the mass ratio of the catnip oil to the mint oil is 1-9: 9-1.

Optionally, the mass ratio of the catmint oil to the mint oil is 3-7: 7-3.

Preferably, the mass ratio of the catmint oil to the mint oil is 7: 3.

The compound mosquito-repellent essential oil is applied to preparing a mosquito repellent, and the mosquito repellent is mosquito repellent liquid, mosquito repellent incense, mosquito repellent paste, mosquito repellent ointment or other mosquito repellent products.

The mosquito repellent is mosquito repellent ointment, active ingredients of the mosquito repellent ointment are catnip oil and mint oil, and the mass ratio of the catnip oil to the mint oil is 1-9: 9-1.

The mosquito repellent is mosquito repellent ointment, active ingredients of the mosquito repellent ointment are catnip oil and mint oil, and the mass ratio of the catnip oil to the mint oil is 3-7: 7-3.

The mosquito repellent is mosquito repellent ointment, the active ingredients of the mosquito repellent ointment are schizonepeta oil and mint oil, and the mass ratio of the schizonepeta oil to the mint oil is 7: 3.

Optionally, the composition is prepared from the following raw materials in percentage by weight: 10-30% of nano material containing active ingredients, 2-10% of emulsifier, 16-24% of dispersant, 15-20% of lubricant and the balance of solvent, wherein the sum of the mass percentages of the raw materials is 100%;

the nano material is nano silicon dioxide, the particle size of the nano silicon dioxide is 80-150 nm, and the drug loading of the nano silicon dioxide is 142.39%.

Optionally, the emulsifier is cetyl alcohol, the dispersant is one of glyceryl monostearate and liquid paraffin, the lubricant is glycerol, and the solvent is water.

Optionally, the preparation method comprises the following steps:

s1: weighing the activated nano-silica material, adding a proper amount of liquid paraffin to completely disperse the nano-silica, and then adding the catnip oil and the peppermint oil according to the formula amount for adsorption to obtain the drug-loaded nano-silica;

s2: melting glyceryl monostearate, cetyl alcohol and paraffin according to the formula amount, and adding the drug-loaded nano-silica as an oil phase;

s3: uniformly mixing glycerol, tween-80 and water in a formula amount to obtain a water phase;

s4: adding the water phase into the oil phase to form viscous white liquid, and cooling to obtain the final product.

The invention has the advantages that:

the catnip oil and the mint oil are natural plant source active substances, and the catnip oil and the mint oil are compounded in a certain proportion to achieve the synergistic effect and have high mosquito repellent activity.

Detailed Description

Based on 12 plant essential oils, the applicant finds that the two plant essential oils with the best mosquito repelling effect are schizonepeta oil and mint oil, the two plant essential oils have high mosquito repelling activity on aedes albopictus under different concentrations, and a nano mosquito repelling ointment with a good mosquito repelling effect can be prepared by compounding the two plant essential oils.

In order to more clearly understand the present invention and the efficacy of the pharmaceutical agent of the present invention, the present invention will be further described in detail by the following specific examples, which are given by the inventors according to the technical scheme of the present invention, and are only preferred examples of the present invention, but not limited to these examples.