阅读说明：本技术 一种降低断奶仔猪腹泻的预混剂、组合物及其制备方法与应用 (Premix and composition for reducing diarrhea of weaned piglets as well as preparation method and application of premix and composition ) 是由 张军 汤建平 刘小成 张敬学 吴有林 于 2019-12-18 设计创作，主要内容包括：本申请提供一种降低断奶仔猪腹泻的预混剂、组合物及其制备方法与应用。一种降低断奶仔猪腹泻的预混剂的原料按照重量份数计包括：有机酸钙盐10-32份、燕麦壳15-25份、鱼油5-15份、谷氨酸钠5-18份、葡萄糖酸锌3-6份,以及载体4-62份,通过配伍共同作用,可促进仔猪肠道健康发育,提高免疫力,同时有效降低断奶仔猪腹泻率。(The application provides a premix for reducing diarrhea of weaned piglets, a composition, and a preparation method and application thereof. The premix for reducing diarrhea of weaned piglets comprises the following raw materials in parts by weight: 10-32 parts of organic acid calcium salt, 15-25 parts of oat hull, 5-15 parts of fish oil, 5-18 parts of sodium glutamate, 3-6 parts of zinc gluconate and 4-62 parts of carrier, and can promote healthy development of intestinal tracts of piglets, improve immunity and effectively reduce diarrhea rate of weaned piglets through compatibility and combined action.)

1. The premix for reducing diarrhea of weaned piglets is characterized by being compounded from the following raw materials in parts by weight:

2. the premix for reducing diarrhea of weaned piglets according to claim 1, wherein the raw materials comprise, in parts by weight:

3. the premix for reducing diarrhea of weaned piglets according to claim 1, wherein the organic calcium salt comprises, in parts by weight: 5-20 parts of calcium butyrate and 5-12 parts of calcium formate; optionally, the calcium salt of an organic acid comprises: 10-20 parts of calcium butyrate and 8-12 parts of calcium formate;

and/or the carrier is corncob meal.

4. A method for preparing the premix for reducing diarrhea in weaned piglets according to any of claims 1 to 3, wherein the fish oil and at least part of the carrier are mixed uniformly and then mixed uniformly with other raw materials.

5. A composition for reducing diarrhea in weaned piglets comprising the premix of any of claims 1 to 3 and a suspension of adult pig feces.

6. The composition for reducing diarrhea in weaned pigs according to claim 5, wherein said suspension of feces of adult pigs is mainly prepared from feces of fresh sows and phosphate buffer at a ratio of 1 g: 5-15mL of the phosphate buffer solution with the concentration of 0.05-0.2M.

7. The composition for reducing diarrhea in weaned pigs according to claim 5, wherein the premix and the suspension of feces from adult pigs are used in a ratio of 1 g: 1-3 ml.

8. A method of preparing a composition for reducing diarrhea in a weaned pig according to claim 5, wherein the premix is mixed with the suspension of feces from an adult pig.

9. Use of a premix for reducing diarrhea in weaned piglets according to any of claims 1 to 3, wherein the premix is added to the creep feed of piglets.

10. Use of a composition according to claim 5 for reducing diarrhea in weaned piglets, wherein the composition is added to the creep feed of the piglets.

Technical Field

The application relates to the field of feed additives, in particular to a premix and a composition for reducing diarrhea of weaned piglets, and a preparation method and application thereof.

Background

The weaning of piglets is a very important turning point in the growing process of pigs, and clinically, the weaning stress of piglets often causes diarrhea. The diarrhea of the weaned piglets can cause the survival rate of the piglets to be reduced, the meat-feed ratio to be reduced, the growth and development to be slow or even stopped, meanwhile, the diarrhea causes the physique to be reduced, the immunity to be reduced, the resistance to diseases is weakened, other diseases are easy to be generated secondarily, and the diarrhea is one of the main factors influencing the benefit of the farm.

At present, methods for treating diarrhea of weaned piglets are divided into preventive measures and therapeutic measures, but most of the methods cannot effectively reduce the diarrhea of the weaned piglets. In view of the above, the present invention is particularly proposed.

Disclosure of Invention

The embodiment of the application aims to provide a premix and a composition for reducing diarrhea of weaned piglets, and a preparation method and application thereof, which are used for promoting healthy development of intestinal tracts, improving immunity and realizing the technical effect of effectively reducing diarrhea of the weaned piglets.

In a first aspect, an embodiment of the application provides a premix for reducing diarrhea of weaned piglets, which is prepared by compounding raw materials, wherein the raw materials comprise, by weight:

in the technical scheme, the organic acid calcium salt can promote the proliferation of beneficial bacteria in the intestinal tract, generate a large amount of beneficial bacteria and maintain the acidic environment in the intestinal tract, thereby inhibiting the proliferation of harmful bacteria. The oat hulls can stimulate the intestinal tract and promote the development of the intestinal tract; the fish oil can lubricate the intestinal tract and promote the development of the intestinal tract; the sodium glutamate can promote the piglet to eat; zinc gluconate can improve immunity. Through the combined action of the raw materials, the feed can promote the healthy development of intestinal tracts of piglets, improve the immunity, promote the ingestion and treat both symptoms and root causes of diarrhea weaned piglets, thereby effectively reducing the diarrhea of the weaned piglets.

In one possible implementation mode, the raw materials comprise the following components in parts by weight:

in the technical scheme, the raw materials have strong synergistic effect according to the proportion, and the obtained premix can obviously reduce the diarrhea of weaned piglets.

In one possible implementation, the organic acid calcium salt comprises, in parts by weight: 5-20 parts of calcium butyrate and 5-12 parts of calcium formate; alternatively, the calcium salt of an organic acid comprises: 10-20 parts of calcium butyrate and 8-12 parts of calcium formate;

and/or the carrier is corncob meal.

In the technical scheme, the calcium butyrate can promote the proliferation of beneficial bacteria, the calcium formate can maintain an acidic environment and inhibit the proliferation of harmful bacteria, and the calcium butyrate and the calcium formate are used in a certain ratio, so that the proliferation of the beneficial bacteria can be effectively promoted, the proliferation of the harmful bacteria can be inhibited, and the healthy development of intestinal tracts can be promoted.

In a second aspect, the present application provides a method for preparing a premix for reducing diarrhea of weaned piglets, which is provided by the first aspect, the fish oil and at least a part of the carrier are mixed uniformly, and then the mixture is mixed uniformly with other raw materials.

In the technical scheme, the fish oil and part of the carrier are uniformly mixed and then are uniformly mixed with other raw materials, so that the caking phenomenon caused by the direct mixing of the fish oil and the other raw materials except the carrier can be avoided, and the effective uniform mixing of the raw materials is ensured.

In a third aspect, the present embodiments provide a composition for reducing diarrhea in weaned piglets, which comprises the premix provided in the first aspect and an adult pig manure suspension.

In the technical scheme, the premix can promote healthy development of intestinal tracts of piglets, improve immunity and promote ingestion, and the adult pig manure suspension can supplement intestinal bacteria for the piglets and promote intestinal health of the piglets.

In one possible implementation, the suspension of adult swine waste is made up of mainly fresh sow waste and phosphate buffer in a ratio of 1 g: 5 to 15mL of the buffer solution is mixed evenly, and the concentration of the phosphate buffer solution is 0.05 to 0.2M.

According to the technical scheme, the adult pig manure suspension formed by fresh sow manure and phosphate buffer solution according to a certain proportion can directly provide the required flora for intestinal tracts for piglets, and can ensure the activity of the flora.

In one possible implementation, the ratio of the amount of premix to the amount of adult swine waste suspension is 1 g: 1-3 ml.

In the technical scheme, the premix and the adult pig manure suspension are combined according to a certain proportion, so that the premix and the adult pig manure suspension can act together to give full play to the efficacy, and the piglet organism is prevented from being damaged due to excessive flora provided by the adult pig manure suspension.

In a fourth aspect, the present application provides a method for preparing the composition for reducing diarrhea of weaned pigs according to the third aspect, the premix is mixed with a suspension of feces of adult pigs.

According to the technical scheme, after the premix and the adult pig manure suspension are uniformly mixed, the premix and the adult pig manure can easily act together, and beneficial bacteria in intestinal tracts can be provided for piglets and can be proliferated, so that the intestinal health is promoted, and the diarrhea of weaned piglets is effectively reduced.

In a fifth aspect, the present embodiments provide a use of the premix for reducing diarrhea of weaned piglets provided in the first aspect, wherein the premix is added to a creep feed for piglets.

In the technical scheme, the premix is added into the creep feed of the piglets, so that the piglets can conveniently eat and take the premix, and the premix can effectively relieve the diarrhea of the piglets and reduce the diarrhea of the piglets.

In a sixth aspect, the present application provides a use of the composition for reducing diarrhea of a weaned pig provided in the third aspect, wherein the composition is added to a creep feed for the piglet.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

The premix and the composition for reducing diarrhea of weaned piglets, and the preparation method and the application thereof according to the embodiments of the present application are specifically described below.

The embodiment of the application provides a premix for reducing diarrhea of weaned piglets, which is prepared by compounding raw materials, wherein the raw materials comprise the following components in parts by weight: 10-32 parts of organic acid calcium salt, 15-25 parts of oat hull, 5-15 parts of fish oil, 5-18 parts of sodium glutamate, 3-6 parts of zinc gluconate and 4-62 parts of carrier, wherein the organic acid calcium salt comprises the following components in parts by weight: 5-20 parts of calcium butyrate and 5-12 parts of calcium formate. Optionally, the raw materials include, by weight: 18-32 parts of organic acid calcium salt, 20-25 parts of oat hull, 8-15 parts of fish oil, 10-18 parts of sodium glutamate, 4-6 parts of zinc gluconate and 4-40 parts of carrier, wherein the organic acid calcium salt comprises the following components in parts by weight: 10-20 parts of calcium butyrate and 8-12 parts of calcium formate. In the actual use process, the raw materials comprise the following components in parts by weight: 10-32 parts of organic acid calcium salt, 15-25 parts of oat hull, 5-15 parts of fish oil, 5-18 parts of sodium glutamate, 3-6 parts of zinc gluconate and the balance of a carrier. Optionally, the raw materials include, by weight: 18-32 parts of organic acid calcium salt, 20-25 parts of oat hull, 8-15 parts of fish oil, 10-18 parts of sodium glutamate, 4-6 parts of zinc gluconate and the balance of a carrier.

Illustratively, the raw materials comprise the following components in parts by weight: 10 parts of organic acid calcium salt, 15 parts of oat hull, 5 parts of fish oil, 5 parts of sodium glutamate, 3 parts of zinc gluconate and 62 parts of carrier; or the raw materials comprise the following components in parts by weight: 18 parts of organic acid calcium salt, 20 parts of oat hull, 8 parts of fish oil, 10 parts of sodium glutamate, 4 parts of zinc gluconate and 40 parts of carrier; or the raw materials comprise the following components in parts by weight: 25 parts of organic acid calcium salt, 25 parts of oat hull, 10 parts of fish oil, 15 parts of sodium glutamate, 5 parts of zinc gluconate and 20 parts of carrier; or the raw materials comprise the following components in parts by weight: 32 parts of organic acid calcium salt, 25 parts of oat hull, 15 parts of fish oil, 18 parts of sodium glutamate, 6 parts of zinc gluconate and 4 parts of carrier; or the raw materials comprise the following components in parts by weight: 25 parts of organic acid calcium salt, 20 parts of oat hull, 10 parts of fish oil, 10 parts of sodium glutamate, 5 parts of zinc gluconate and 30 parts of carrier.

In this embodiment, the carrier is not particularly limited, and only needs to carry other raw materials, and can be edible, such as one or a mixture of at least two of soybean meal, rice bran meal, corncob meal, and the like. In the embodiment, the carrier is corncob powder, so that the intestinal tracts of piglets are hardly stimulated.

In this embodiment, the solid raw materials including oat hulls are all in powder form, that is, the solid raw materials are pulverized into a certain particle size, generally below 50 meshes, so as to facilitate the ingestion and digestion of piglets.

The embodiment of the application also provides a preparation method of the premix for reducing diarrhea of weaned piglets, which comprises the steps of uniformly mixing the fish oil and at least part of carriers, and uniformly mixing the fish oil and other raw materials.

Optionally, the fish oil and the carrier with the weight not less than that of the fish oil are mixed uniformly according to the weight ratio of 1:1-2, for example, the fish oil and the corncob meal with the same weight are mixed uniformly and then mixed uniformly with other raw materials.

The embodiment of the application also provides an application of the premix for reducing diarrhea of the weaned piglets, and the premix is added into a creep feed for the piglets to relieve the diarrhea of the piglets. Optionally, 1-3g premix is added per 100g of creep.

In addition, the embodiment of the application provides a composition for reducing diarrhea of weaned piglets, which comprises the premix and the adult pig manure suspension, and in the embodiment, the dosage ratio of the premix to the adult pig manure suspension can be 1 g: 1-3 ml.

Since the feces of the adult pigs contain intestinal flora, the intestinal flora required by the intestinal tract of the piglets is provided for the piglets by adopting the feces suspension of the adult pigs, which is optional, the feces suspension of the adult pigs is mainly prepared by mixing fresh sow feces and phosphate buffer solution according to the dosage ratio of 1 g: 5 to 15mL of the buffer solution is mixed evenly, and the concentration of the phosphate buffer solution is 0.05 to 0.2M.

The embodiment of the application also provides a preparation method of the composition for reducing diarrhea of weaned piglets, which specifically comprises the following steps:

(1) preparing an adult pig manure suspension: taking fresh sow manure under anaerobic and aseptic conditions to facilitate centrifuging tubes, wherein the fresh sow manure is taken from a centrifuge tube according to the dosage ratio of 1 g: adding 5-15mL (mass-volume ratio) of sterile pre-reduced phosphate buffer solution (0.05-0.2M), and shaking and mixing uniformly to obtain an adult pig manure suspension.

(2) Mixing the premix and the adult pig manure suspension according to the dosage ratio of 1 g: mixing 1-3 ml.

The embodiment of the application also provides application of the composition for reducing the diarrhea of the weaned piglets, and the composition is added into a creep feed of the piglets. The creep feed is a feed prepared for replacing whole milk, is a feed for teaching piglets to eat, and is mainly prepared from dairy byproducts, wherein the nutritional indexes of the creep feed are that protein is not less than 20% and fat is not less than 6%. Alternatively, 2-6ml of the composition is added per 100g of the milk.

The features and properties of the present application are described in further detail below with reference to examples.