阅读说明：本技术 一种染色体酶激活因子护眼膏及制备方法 (Eye cream containing chromosomal enzyme activating factor and preparation method thereof ) 是由 王虎 于 2018-09-13 设计创作，主要内容包括：本发明公开了一种染色体酶激活因子护眼膏,其原料按重量份计为：水10-30份,复合染色体酶激活因子1-3份,薄荷5-20份,黄原胶0.5-1份,丙二醇10-20份,桂圆肉2-4份,天然冰片0.5-1.5份,三七提取物0.5-2份,金银花提取物0.5-2份,枸杞子2-8份、菊花6-10份、决明子12-20份。本发明的护眼膏制备方法为：将复合染色体酶激活因子,薄荷、黄原胶、丙二醇、桂圆肉、天然冰片、三七提取物、金银花提取物、枸杞子、菊花、决明子混合后,搅拌直至形成均匀的浸膏既得染色体酶激活因子护眼膏。本发明的护眼膏安全性高,辅助改善眼底病变、老花眼、飞蚊症、玻璃体混浊、黄斑变性、视神经萎缩、假性近视、弱视、远视、视力下降、眼发痒、干涩、疼痛、酸胀、流泪、结膜炎、沙眼的疾病。而且复合染色体酶激活因子眼膏,还适用于老人和儿童人群。(The invention discloses an eye cream containing a chromosomal enzyme activating factor, which comprises the following raw materials in parts by weight: 10-30 parts of water, 1-3 parts of compound chromosomal enzyme activating factor, 5-20 parts of mint, 0.5-1 part of xanthan gum, 10-20 parts of propylene glycol, 2-4 parts of longan pulp, 0.5-1.5 parts of natural borneol, 0.5-2 parts of pseudo-ginseng extract, 0.5-2 parts of honeysuckle extract, 2-8 parts of wolfberry fruit, 6-10 parts of chrysanthemum and 12-20 parts of cassia seed. The preparation method of the eye protection cream comprises the following steps: mixing the compound chromosomal enzyme activating factor, mint, xanthan gum, propylene glycol, longan pulp, natural borneol, pseudo-ginseng extract, honeysuckle extract, medlar, chrysanthemum and cassia seed, and stirring until uniform extractum is formed to obtain the chromosomal enzyme activating factor eye cream. The eye protection ointment has high safety, and can be used for assisting in improving diseases such as eyeground pathological changes, presbyopia, muscae volitantes, vitreous opacity, macular degeneration, optic atrophy, pseudomyopia, amblyopia, hypermetropia, visual deterioration, eye itching, dryness, pain, acid swelling, lacrimation, conjunctivitis and trachoma. And the compound chromosome enzyme activating factor eye ointment is also suitable for the old and children.)

1. An eye cream containing a chromosomal enzyme activating factor is characterized by comprising the following components in proportion: 10-30 parts of water, 1-3 parts of compound chromosomal enzyme activating factor, 5-20 parts of mint, 0.5-1 part of xanthan gum, 10-20 parts of propylene glycol, 2-4 parts of longan pulp, 0.5-1.5 parts of natural borneol, 0.5-2 parts of pseudo-ginseng extract, 0.5-2 parts of honeysuckle extract, 2-8 parts of wolfberry fruit, 6-10 parts of chrysanthemum and 12-20 parts of cassia seed.

2. An eye cream containing the composite chromosomal enzyme activator is prepared from the extract of yellow wine yeast through breaking cell wall and bioengineering, including the enzyme activators of EST1, EST2 EST3, TLCI and CDCI3 nuclear genes in yeast nucleic acid.

3. The eye ointment as claimed in claim 1, wherein the purity of the natural borneol is not less than 98.5%.

4. The eye cream as claimed in claim 1, wherein the extracts of fructus Lycii, flos Chrysanthemi, and semen Cassiae.

5. The eye ointment as set forth in claims 1 to 4, which is prepared by: mixing compound chromosomal enzyme activating factor, water, xanthan gum, propylene glycol, arillus longan, natural Borneolum Syntheticum, Notoginseng radix extract, flos Lonicerae extract, fructus Lycii, flos Chrysanthemi, and semen Cassiae, and high-speed shearing at 33-42 deg.C and stirring for 60-65min to obtain uniform extract.

6. The method for preparing an eye ointment for treating chromosomal enzyme activator according to claim 5, wherein the high shear rate is 6000-10000 rpm/min.

Background

According to the statistics of the world health organization (WH0), 4500 million people exist in the world, 1 hundred million and 8 million people exist in people with eye diseases, and various types of eye diseases exist. Age-related macular degeneration is a significant cause of vision loss and blindness in the elderly, and senile eye disease is the leading cause of blindness in middle aged and elderly people over 55 years of age in western countries. The number of people worldwide suffering from age-related macular degeneration (AMD) causing blurred vision and blindness is 2500-3000 ten thousand. According to research and analysis, except age and genetic factors, the method has a relationship with the intake of antioxidants in food, sunlight stimulation, radiation, smoking, working environment and the like, the quality and quantity of information communication are continuously improved along with the rapid development of scientific technology, and the method is developed from the treatment of traditional white and black paper to computer operation, and electrical equipment assembled by a cathode ray tube enters the society and families. Recent research shows that computer terminals can cause visual fatigue, also called VDT syndrome. The major ocular symptoms of VDT syndrome are: soreness, swelling, discomfort, difficulty concentrating, conjunctivitis or keratitis, even vision loss, increased intraocular pressure, and myopia. Systemic symptoms are: mainly treating general aching pain of shoulder, neck, waist and back, dysphoria, vegetative nerve functional disturbance, etc.

The eye cell chromosome telomerase is an enzyme consisting of a catalytic protein and an RNA template, and can synthesize DNA at the end of a chromosome to endow the cell with the immortality of replication. The Nobel expert panel considers that telomerase plays a key role in prolonging the life of human beings and treating diseases and function deterioration caused by various aging, and whether cells can continuously divide is not important, but the differentiated and mature cells bear a more important mission, namely, tissues and organs are operated to enable the life to be continued. By reasonably applying the technology of extracting the biological telomerase, the physiological age of human beings around the world can be increased inversely, and a plurality of chronic diseases which disturb the medical field can be treated. In 2009 elizabeth brankeben, carol grede and professor jack shashsha medical college, three american scientists found an enzyme in the cell responsible for the elongation of telomeres, named telomerase. The discovery of the telomerase leads human to see the eosin for resisting aging and curing diseases, the telomerase can fill up the telomere lost by DNA replication, and the repair and the extension of the telomere can lead the telomere not to be lost due to cell division, thereby increasing the number of cell division. Three scientists thus receive the current year's reward for nobel's physiology or medicine. Scientists have found that the human body is composed of cells, and people have aging and the cells also have aging. This is like a building, the life of which is largely related to the bricks that make up it. Cells are life-long, discovered by the cytologist hoffick (Hayflick) forty years ago, and grow human fibroblasts, one generation after another. However, in the case of a sufficient supply of nutrients, the cells cease to function until about 50 passages and actually enter the senescence phase, and the finding seems to tell that there is a senescence clock in the cells, which limits the number of cell divisions and thus the life span of the organism. Since the life-prolonging organism is formed by dividing a fertilized egg cell, the life-prolonging organism is divided into two parts, two parts and four parts, and the like to proliferate to form a fetus, and then the fetus is divided into young people. If the cells are no longer dividing, the individual undergoes cell death. The American Alpton International Biotech company successfully extracts a protease-telomerase factor activated protein (telomerase activator, which can repair human cells, fill up telomeres lost by DNA replication and repair and prolong the length of the telomeres) from yeast to reconstruct cell functions, repair human stem cell technology, improve human cell division and can be effectively used for treating eye diseases and complications of the eye diseases.

Disclosure of Invention

The invention provides an eye protection ointment containing a chromosomal enzyme activating factor, which is prepared by adding a compound chromosomal enzyme activating factor, extracts of natural borneol, pseudo-ginseng and the like and a honeysuckle extract into the eye protection ointment as active ingredients, so that the eye protection ointment has good safety and has multiple effects.

The invention adopts the following technical scheme: the eye cream containing the chromosomal enzyme activating factor comprises the following raw materials in parts by weight: 10-30 parts of water, 1-3 parts of compound chromosomal enzyme activating factor, 5-20 parts of mint, 0.5-1 part of xanthan gum, 10-20 parts of propylene glycol, 2-4 parts of longan pulp, 0.5-1.5 parts of natural borneol, 0.5-2 parts of pseudo-ginseng extract, 0.5-2 parts of honeysuckle extract, 2-8 parts of wolfberry fruit, 6-10 parts of chrysanthemum and 12-20 parts of cassia seed. Mixing propylene glycol, arillus longan, natural Borneolum Syntheticum, Notoginseng radix extract, flos Lonicerae extract, fructus Lycii, flos Chrysanthemi, and semen Cassiae, and shearing at 33-42 deg.C for 60-65min to obtain uniform extract. Further, the rotating speed of the high-speed shearing is 6000-10000 rpm/min. The invention has the advantages that: compared with the traditional eye protection ointment, the compound chromosomal enzyme activating factor added in the eye protection ointment is safe and non-toxic, has good physiological compatibility, and has the effects of clearing heat and relieving pain when being used with traditional Chinese medicines, and the eye protection ointment is compounded with the pseudo-ginseng extract and the honeysuckle extract for the first time, so that the eye protection ointment has an eye patch which can assist in improving eyeground pathological changes, presbyopia, muscae volitantes, vitreous opacity, macular degeneration, optic atrophy, pseudomyopia, hypermetropia, amblyopia, visual deterioration, dry and astringent eyes, itching, acid swelling, pain, lacrimation, conjunctivitis and trachoma; the compound chromosome enzyme activating factor eye ointment is suitable for teenagers, and children 3-4 years old and children 90 years old, and has obvious curative effect on eye ulcer, red swelling and eyeball congestion. The components added in the invention are all natural components, so that the product is more environment-friendly, green and healthy. In addition, the invention adopts a shear type high-speed mixing technology, utilizes high-speed rotation to fully mix all components, can greatly save mixing time and improve production and time efficiency.

Drawings

FIG. 1 shows the result of one month treatment of eyeground haemorrhage patients with the eye protection ointment of the invention. A, bleeding area image before treatment, B, recovery area image after one month of treatment.

Fig. 2 is a one month treatment result for treating eye disease patients with different symptoms, such as fundus oculi lesion, vitreous opacity, conjunctival hemorrhage, eye pain, and eye fatigue. The experimental group was treated with eye cream of chromosomal enzyme activating factor, the positive control group with chloramphenicol eye drops and the negative control group with normal saline, each group containing six patients.

Detailed Description

The following will further describe a chromosomal enzyme activator eye cream according to the present invention with reference to specific examples.