阅读说明：本技术 一种消毒剂的泡沫型助剂及其制备方法 (Foam type auxiliary agent of disinfectant and preparation method thereof ) 是由 杜海峰 孙艳红 徐宁宁 于 2019-11-01 设计创作，主要内容包括：本发明公开了一种消毒剂的泡沫型助剂及其制备方法。所述助剂包括如下重量份的原料：发泡剂1～20份,稳泡剂0.5～10份,pH调节剂1～10份,水60～97.5份。本发明所述助剂可以产生丰富、细腻的泡沫,可进行5～50倍体积发泡,与杀菌成分戊二醛、季铵盐协同作用,可提高杀菌效率,有效杀灭细菌、病毒、芽孢,能够实现大规模对动物、牧场及畜禽栏舍、兽医临床器械的消毒,极大节约了使用成本,减少资源浪费；本发明所述消毒剂的泡沫型助剂产品制备方法操作简单,原料易得,适合规模化生产。(The invention discloses a foam type auxiliary agent of a disinfectant and a preparation method thereof. The auxiliary agent comprises the following raw materials in parts by weight: 1-20 parts of foaming agent, 0.5-10 parts of foam stabilizer, 1-10 parts of pH regulator and 60-97.5 parts of water. The auxiliary agent can generate rich and fine foam, can be foamed by 5-50 times in volume, can be used for synergistically acting with sterilization components of glutaraldehyde and quaternary ammonium salt, can improve the sterilization efficiency, effectively kill bacteria, viruses and spores, can realize large-scale sterilization of animals, pastures, livestock and poultry houses and veterinary clinical instruments, greatly saves the use cost and reduces the resource waste; the preparation method of the foam type auxiliary agent product of the disinfectant is simple to operate, easily available in raw materials and suitable for large-scale production.)

1. A foam type auxiliary agent of a disinfectant is characterized in that the foam type auxiliary agent is used for a quaternary ammonium salt/glutaraldehyde disinfectant and comprises the following raw materials in parts by weight: 1-20 parts of foaming agent, 0.5-10 parts of foam stabilizer, 1-10 parts of pH regulator and 60-97.5 parts of water.

2. The foam adjuvant for disinfectant according to claim 1, wherein said foaming agent comprises nonionic surfactant or zwitterionic surfactant, said nonionic surfactant comprises one or combination of fatty alcohol polyoxyethylene ether, polyoxyethylated ionic surfactant, coconut oil fatty acid diethanolamide, and alkanolamide polyoxyethylether;

the zwitterionic surfactant comprises one or a combination of dodecyl dimethyl ammonium oxide, cocamidopropyl betaine, lauramidopropyl betaine and octadecyl dihydroxyethyl amine oxide.

3. The foam adjuvant for disinfectant according to claim 1, wherein said foam stabilizer comprises one or a combination of polyacrylamide, polyvinyl alcohol, polyvinylpyrrolidone or polyethylene oxide.

4. The foam adjuvant for disinfectant according to claim 1, wherein said pH regulator comprises inorganic acid or organic acid, said inorganic acid comprises one or combination of hydrochloric acid, phosphoric acid, nitric acid, sulfuric acid; the organic acid comprises one or a combination of lactic acid, acetic acid and citric acid.

5. A method of preparing a foam adjuvant for disinfectants according to any of claims 1 to 4, comprising:

mixing a foaming agent, a foam stabilizer and water in proportion;

slowly stirring at a constant speed, and simultaneously adding a pH regulator to regulate the pH value to a set range;

continuously stirring for the first time; and

stopping stirring, and standing for a second time.

6. The method according to claim 5, wherein the pH is set within a range of 2 to 5.

7. The method of claim 5, wherein the first time is between 1.0 and 2.5 hours.

8. The method of claim 5, wherein the second time is between 0.8 and 1.2 hours.

9. The method of claim 5, wherein the stirring speed is 5 to 150 rpm.

Technical Field

The invention belongs to the technical field of veterinary products, and particularly relates to a foam type auxiliary agent of a disinfectant and a preparation method thereof.

Background

In recent years, with the increasing intensification degree of the livestock breeding industry, the breeding density is increased, the transmission speed of infectious diseases of animals is increased, and various animal epidemic diseases emerge endlessly. At present, the application of disinfectants to disinfect and treat livestock and poultry housing, environment and livestock and poultry diseases becomes an important measure for preventing and controlling the livestock and poultry diseases.

Glutaraldehyde is an aldehyde disinfectant, the killing effect of the aldehyde disinfectant on microorganisms mainly depends on aldehyde groups, and the medicines mainly act on mycoprotein to cause protein coagulation to cause bacterial death, and the action mechanism is as follows: unsaturated aldehyde groups existing in the aldehyde solution can act on mercapto, hydroxyl, carboxyl and amino of mural lipoprotein or other components, so that after alkylation, mural protein is crosslinked or lipid chain residues in mural teichoic acid form side chains, thereby closing cell walls, and preventing microorganisms from absorbing nutrient substances and discharging wastes; in addition, glutaraldehyde can inhibit the activity of dehydrogenase and periplasmatase, and inhibit the synthesis of RNA, DNA and protein, thereby achieving the effect of quick sterilization. Glutaraldehyde: has broad-spectrum, high-efficiency and quick-acting bactericidal action. Broad-spectrum sterilization, which can kill all microorganisms in propagules such as bacteria, viruses, fungi, bacterial spores, fungal spores, mycobacteria and the like; the sterilizing and inflammation diminishing effect is good, the permeability is strong, and the sterilizing effect is high; the performance is stable. The sterilization agent is not influenced by water quality (soft and hard) and temperature, and has strong bactericidal power at low temperature; fixing hoof, protecting hoof, and increasing hardness of hoof cutin.

The quaternary ammonium salt has lipophilic disinfection effect, is used as cationic surfactant, has strong wetting effect, and can dissolve bacterial cell wall, cell membrane and virus envelope, resulting in membrane permeability change and component outflow. Glutaraldehyde has hydrophilic disinfection effect, and is combined with capsid protein of virus and enzyme of microorganism to solidify protein; binding to microbial nucleic acids denatures the nucleic acids and kills the microbes. With the help of the lipophilic disinfectant quaternary ammonium salt, the glutaraldehyde can enter the microbial cells to rapidly exert the effect.

The quaternary ammonium salt/glutaraldehyde disinfectant has been widely applied to the livestock breeding industry and is used for disinfecting animals, pastures, livestock and poultry houses and veterinary clinical instruments. Can effectively kill bacteria, viruses and spores. However, the quaternary ammonium salt/glutaraldehyde disinfectant is diluted and used as a liquid, so that a large amount of liquid is wasted and is inconvenient to observe.

Disclosure of Invention

In view of the above-mentioned drawbacks of the prior art, the present invention provides a foam-type adjuvant for disinfectant and a preparation method thereof, so as to solve the above-mentioned problems.

According to a first aspect of the invention, a foam type auxiliary agent of a disinfectant is provided, which comprises the following raw materials in parts by weight: 1-20 parts of foaming agent, 0.5-10 parts of foam stabilizer, 1-10 parts of pH regulator and 60-97.5 parts of water.

Preferably, for the foam-type assistant of the disinfectant, the foaming agent comprises a nonionic surfactant or a zwitterionic surfactant, and the nonionic surfactant comprises one or a combination of fatty alcohol-polyoxyethylene ether, a polyoxyethylenated ionic surfactant, coconut oil fatty acid diethanolamide and alkanolamide polyoxyethylether;

the zwitterionic surfactant comprises one or a combination of dodecyl dimethyl ammonium oxide, cocamidopropyl betaine, lauramidopropyl betaine and octadecyl dihydroxyethyl amine oxide.

Preferably, for the foam-type assistant of the disinfectant, the foam stabilizer comprises any one or a combination of polyacrylamide, polyvinyl alcohol, polyvinylpyrrolidone or polyethylene oxide.

Preferably, for the foam type auxiliary agent of the disinfectant, the pH regulator comprises inorganic acid or organic acid, and the inorganic acid comprises one or a combination of hydrochloric acid, phosphoric acid, nitric acid and sulfuric acid;

the organic acid comprises one or a combination of lactic acid, acetic acid and citric acid.

According to a second aspect of the present invention, there is provided a method of preparing a foam adjuvant for a disinfectant, comprising:

mixing a foaming agent, a foam stabilizer and water in proportion;

slowly stirring at a constant speed, and simultaneously adding a pH regulator to regulate the pH value to a set range;

continuously stirring for the first time; and

stopping stirring, and standing for a second time.

Preferably, for the preparation method, the set range of the pH is 2-5.

Preferably, for the preparation method, the first time is between 1.0 and 2.5 hours.

Preferably, for the preparation process, the second time is between 0.8 and 1.2 h.

Preferably, for the preparation method, the stirring speed is 5-150 rpm.

The water is deionized water, which means the deionized water after removing impurities in the form of ions.

Compared with the prior art, the foam type auxiliary agent for the disinfectant and the preparation method thereof provided by the invention have the technical effects that at least: the auxiliary agent can generate rich and fine foam, can perform 5-50 times of volume foaming, can uniformly distribute the disinfectant in the foam under the synergistic action of the disinfectant components glutaraldehyde and quaternary ammonium salt, increases the distribution area of the disinfectant, can better play the role of the disinfectant, improves the sterilization efficiency, effectively kills bacteria, viruses and spores, can realize large-scale sterilization of animals, pastures, livestock and poultry houses and veterinary clinical instruments, greatly saves the use cost and reduces the resource waste; the preparation method of the foam type auxiliary agent product of the disinfectant is simple to operate, easily available in raw materials and suitable for large-scale production.

Detailed Description

The present invention will be described below with reference to specific examples, but the present invention is not limited thereto. The experimental methods described in the following examples are all conventional methods unless otherwise specified; the reagents and materials are commercially available without specific reference, and the following examples are not intended to limit the scope of the present invention, and all equivalent implementations or modifications without departing from the scope of the present invention are intended to be included in the scope of the present invention.

The embodiment of the invention provides a foam type auxiliary agent of a disinfectant, which comprises the following raw materials in parts by weight: 1-20 parts of foaming agent, 0.5-10 parts of foam stabilizer, 1-10 parts of pH regulator and 60-97.5 parts of water.

Preferably, for the foam-type assistant of the disinfectant, the foaming agent comprises a nonionic surfactant or a zwitterionic surfactant, and the nonionic surfactant comprises one or a combination of fatty alcohol-polyoxyethylene ether, a polyoxyethylenated ionic surfactant, coconut oil fatty acid diethanolamide and alkanolamide polyoxyethylether;

the zwitterionic surfactant comprises one or a combination of dodecyl dimethyl ammonium oxide, cocamidopropyl betaine, lauramidopropyl betaine and octadecyl dihydroxyethyl amine oxide.

Preferably, for the foam-type assistant of the disinfectant, the foam stabilizer comprises any one or a combination of polyacrylamide, polyvinyl alcohol, polyvinylpyrrolidone or polyethylene oxide.

Preferably, for the foam type auxiliary agent of the disinfectant, the pH regulator comprises inorganic acid or organic acid, and the inorganic acid comprises one or a combination of hydrochloric acid, phosphoric acid, nitric acid and sulfuric acid;

the organic acid comprises one or a combination of lactic acid, acetic acid and citric acid.

The auxiliary agent and the quaternary ammonium salt/glutaraldehyde disinfectant are produced separately, when the disinfectant is used, the auxiliary agent and the disinfectant are mixed according to a certain proportion and then diluted, the auxiliary agent can generate abundant foam by special equipment, and the quaternary ammonium salt/glutaraldehyde disinfectant carried by the foam directly acts on the disinfection of animals, pastures, livestock and poultry houses and veterinary clinical instruments, can effectively kill bacteria, viruses and spores, can generate abundant and fine foam, reduces resource waste, saves cost, and can also act synergistically with the sterilization components glutaraldehyde and quaternary ammonium salt to improve the sterilization efficiency.

In the embodiment of the invention, the auxiliary agent can be prepared by the following method:

mixing a foaming agent, a foam stabilizer and water in proportion;

slowly stirring at a constant speed, and simultaneously adding a pH regulator to regulate the pH value to a set range;

continuously stirring for the first time; and

stopping stirring, and standing for a second time.

Preferably, for the preparation method, the set range of the pH is 2-5.

Preferably, for the preparation method, the first time is between 1.0 and 2.5 hours.

Preferably, for the preparation process, the second time is between 0.8 and 1.2 h.

Preferably, for the preparation method, the stirring speed is 5-150 rpm.

The water is deionized water, which means the deionized water after removing impurities in the form of ions.

The method is simple, the raw materials are easy to obtain, and the method is suitable for large-scale production.