阅读说明：本技术 一种自适应体型的小动物夹持保温装置及其控制方法 (Small animal clamping and heat-preserving device adaptive to body shape and control method thereof ) 是由 耿慕峰 卢闫晔 任秋实 于 2019-11-25 设计创作，主要内容包括：本发明公开了一种自适应体型的小动物夹持保温装置及其控制方法。本发明采用具有弹性的囊体,有效地减少对小动物的伤害；同时通过流体速度控制及加热装置实时地调节流体的注入速度,以实现对小动物的精准压力夹持,一方面能够适应更多体型大小的小动物,另一方面能够更加精确的将压力分段控制在小动物身体的不同区域；通过实时调节流体的温度,能够有效地将实验温度控制在要求范围内；除此以外,此装置使小动物保持立着的姿态,对于一些需要让小动物长时间处于立姿状态的一些特殊设计的实验装置,具有广大的应用前景；本发明提高了固定压力精度,实现了温度实时调节,减少了对小动物的伤害,简化了实验人员操作复杂度。(The invention discloses a self-adaptive body type small animal clamping and heat-insulating device and a control method thereof. The elastic capsule is adopted, so that the damage to the small animals is effectively reduced; meanwhile, the injection speed of the fluid is adjusted in real time through the fluid speed control and heating device, so that accurate pressure clamping on the small animals is realized, on one hand, the small animals with more body sizes can be adapted, and on the other hand, the pressure can be controlled in different areas of the bodies of the small animals in a segmented mode more accurately; the experimental temperature can be effectively controlled within a required range by adjusting the temperature of the fluid in real time; in addition, the device enables the small animal to keep a standing posture, and has wide application prospect for some specially designed experimental devices which need to enable the small animal to be in a standing posture state for a long time; the invention improves the precision of the fixed pressure, realizes the real-time adjustment of the temperature, reduces the damage to the small animals and simplifies the operation complexity of experimenters.)

1. The utility model provides a little animal centre gripping heat preservation device of self-adaptation size which characterized in that, little animal centre gripping heat preservation device of self-adaptation size includes: the device comprises an outer housing, an upper baffle, a lower baffle, a capsule body, a sensor unit, an inflow pipeline, a drainage pipeline, an inflow valve, a drainage valve, a fluid speed control and heating device, an A/D conversion circuit and a controller; the outer casing is a shell with a cylindrical space inside; a lower baffle is arranged at the bottom of the outer housing; the bag body is arranged in the outer housing, the bag body surrounds the inner wall of the outer housing, a through hole is formed in the middle of the bag body, a closed space is formed by the wall of the bag body in a surrounding mode, the bag body gradually expands inwards and is extruded along with the increase of injected fluid, and the bag body is made of elastic materials; the height of the outer cover shell is greater than the maximum height of the bag body after being filled with fluid; an upper baffle is arranged at the top of the outer housing; the upper baffle and the lower baffle are both provided with vent holes which are coaxial with the through holes of the bag body; a sensor unit is arranged on the outer surface of the through hole of the capsule body and comprises one or more pressure sensors and one or more temperature sensors; the sensor unit is connected to an A/D conversion circuit outside the outer housing; the A/D conversion circuit is connected to the controller; the bag body is provided with a flow inlet pipeline and a flow outlet pipeline which are respectively communicated with the closed space in the bag body; the inflow pipeline and the drainage pipeline are respectively connected to the fluid speed control and heating device through an inflow valve and a drainage valve; the fluid speed control and heating device is connected to the controller; the bag body, the sensor unit, the inflow pipeline, the drainage pipeline, the inflow valve, the drainage valve and the fluid speed control and heating device form a bag body mode assembly; the self-adaptive small animal clamping and heat preservation device adopts one or more sets of bag-shaped mode components; for the multi-set capsule mode assembly, a plurality of capsules are sequentially stacked in the outer housing from top to bottom, and through holes in the plurality of capsules are coaxial; when the capsule body is not filled with fluid, the small animal is put into the through hole in the middle of the capsule body and covered with the baffle; the fluid speed control and heating device fills fluid into the bag body through the inlet valve and the inlet pipeline, and flows back to the fluid speed control and heating device through the outlet pipeline and the outlet valve; the sensor unit collects temperature and pressure signals at the through hole of the capsule body and transmits the temperature and pressure signals to the A/D conversion circuit; the A/D conversion circuit converts the analog signal into a digital signal and transmits the digital signal to the controller; the controller adjusts the fluid speed control and the heating temperature of the heating device to the fluid according to the measured temperature signal so as to adjust the temperature of the through hole of the capsule body; the controller controls the injection speed of the fluid through the fluid speed control and heating device according to the measured pressure signal, so as to adjust the pressure at the through hole of the capsule body; the utricule has elasticity, under the unchangeable circumstances of bleeder valve aperture, adjusts the injection velocity of fluid through fluid speed control and heating device and can accurately control the utricule to the pressure of toy, finally realizes the maintenance and the control of pressure to the toy body temperature.

2. The adaptive-body-type small-animal holding and heat preserving device as claimed in claim 1, wherein the upper and lower baffles are connected with the outer casing by a snap-fit connection.

3. The adaptive-type small-animal holding and warming device according to claim 1, wherein the fluid speed control and heating device comprises: the device comprises a heating rod, a fluid conveying pipe, a fluid storage box, a fluid supply valve and a centrifugal pump; wherein the heating rod and the centrifugal pump are connected to the controller; the inlet of the fluid conveying pipe is connected to a drainage pipeline through a drainage valve; the fluid conveying pipe is wound on the heating rod; the outlet of the fluid delivery pipe is connected to the fluid storage box; the bottom of the fluid storage box is connected to the inlet of the centrifugal pump, and the outlet of the centrifugal pump is connected to the inflow pipeline through the inflow valve; a fluid replenishing valve is arranged at the top of the fluid storage box; replenishing fluid to the fluid reservoir through a fluid replenishment valve; the fluid in the capsule body is recovered to the fluid conveying pipe through the drainage pipeline and the drainage valve, and flows through the heating rod to heat the fluid; the controller controls the heating time of the heating rod so as to enable the temperature of the fluid to reach a set value; the heated fluid enters a fluid storage box; the fluid flows from the storage tank to the centrifugal pump, and the controller controls the flow rate of the fluid by controlling the rotating speed of an impeller of the centrifugal pump, so that the temperature and the flow rate of the fluid are controlled.

4. The adaptive-type small-animal holding and warming device according to claim 1, wherein the material of the bladder is one of rubber, latex and polyurethane having elasticity.

5. The adaptive-type small-animal holding and warming device according to claim 1, wherein the fluid is a gas or a liquid.

6. A control method of a self-adaptive small animal holding and heat preserving device is characterized by comprising the following steps:

1) according to the temperature requirement of the experiment, firstly, preheating the fluid in a fluid speed control and heating device;

2) opening an inflow valve, closing a discharge valve, starting a fluid speed control and heating device, and judging whether the pressure reaches a set pressure initial value or not by a controller through a pressure signal from a sensor unit;

3) when the measured pressure is equal to a set initial value, the controller initiates an instruction to the fluid speed control and heating device, opens the drainage valve, and the fluid speed control and heating device fills fluid into the bag body through the drainage valve and the inlet pipeline and flows back to the fluid speed control and heating device through the drainage pipeline and the drainage valve;

4) the sensor unit collects temperature and pressure signals at the through hole of the capsule body and transmits the temperature and pressure signals to the A/D conversion circuit; the A/D conversion circuit converts the analog signal into a digital signal and transmits the digital signal to the controller;

5) the controller adjusts the fluid speed control and the heating temperature of the heating device to the fluid according to the measured temperature signal so as to adjust the temperature of the through hole of the capsule body; the capsule body has elasticity, and the controller can accurately control the pressure at the through hole of the capsule body by controlling the fluid speed and adjusting the injection speed of the fluid through the heating device under the condition that the aperture of the drain valve is not changed according to the measured pressure signal; finally, the control of temperature and pressure is realized;

6) and after the experiment is finished, closing the inflow valve and opening the drainage valve to release the fluid.

Technical Field

The invention relates to the technology of medical experiment auxiliary devices, in particular to a self-adaptive body type small animal clamping and heat-insulating device and a control method thereof.

Background

In some medical experiments, it is desirable to immobilize and maintain a body temperature in small animals. The current methods of fixation include holding the small animal in place by a combination of rigid plates or holding the small animal in place by a clamp on its limb. The current heat preservation devices for small animals mostly adopt a mode of covering the body of the small animal with heat preservation materials such as quilts. Generally, most of the existing clamping and heat-preserving devices for small animals are fixed, and the clamping and heat-preserving methods have certain limitations. On one hand, the small animals are easily damaged, on the other hand, most of the clamping and heat preservation methods are only suitable for the lying or lying posture of the small animals and cannot be suitable for special experimental environments needing the small animals to keep the standing posture, particularly for the mice, the mice always keep the standing posture in the upward climbing process, and the holding of the mice in the standing posture is very important and necessary in specific research. In addition, some specially designed experimental devices also need to keep the small animals in a standing state for a long time.

Therefore, there is a need for a small animal holding and warming device which does not cause damage to small animals, can adapt to the standing position of small animals and can maintain normal body temperature.

Disclosure of Invention

In order to solve the problems and the defects in the background technology, the invention provides a self-adaptive body type small animal clamping and heat-insulating device and a control method thereof; automatically pressurizing and fixing the small animals with different body states and sizes to a set pressure threshold value by controlling the speed of the fluid; fixing the small animal in a standing posture to adapt to a specific research experiment scene; while the small animals are kept warm by the preheated fluid.

The invention aims to provide a self-adaptive small animal holding and heat preserving device.

The adaptive-size small animal holding and heat preserving device comprises: the device comprises an outer housing, an upper baffle, a lower baffle, a capsule body, a sensor unit, an inflow pipeline, a drainage pipeline, an inflow valve, a drainage valve, a fluid speed control and heating device, an A/D conversion circuit and a controller; the outer casing is a shell with a cylindrical space inside; a lower baffle is arranged at the bottom of the outer housing; the bag body is arranged in the outer housing, the bag body surrounds the inner wall of the outer housing, a through hole is formed in the middle of the bag body, a closed space is formed by the wall of the bag body in a surrounding mode, the bag body gradually expands inwards and is extruded along with the increase of injected fluid, and the bag body is made of elastic materials; the height of the outer cover shell is greater than the maximum height of the bag body after being filled with fluid; an upper baffle is arranged at the top of the outer housing; the upper baffle and the lower baffle are both provided with vent holes which are coaxial with the through holes of the bag body; a sensor unit is arranged on the outer surface of the through hole of the capsule body and comprises one or more pressure sensors and one or more temperature sensors; the sensor unit is connected to an A/D conversion circuit outside the outer housing; the A/D conversion circuit is connected to the controller; the bag body is provided with a flow inlet pipeline and a flow outlet pipeline which are respectively communicated with the closed space in the bag body; the inflow pipeline and the drainage pipeline are respectively connected to the fluid speed control and heating device through an inflow valve and a drainage valve; the fluid speed control and heating device is connected to the controller; the bag body, the sensor unit, the inflow pipeline, the drainage pipeline, the inflow valve, the drainage valve and the fluid speed control and heating device form a bag body mode assembly; one or more sets of balloon mode components are adopted; for the multi-set capsule mode assembly, a plurality of capsules are sequentially stacked in the outer housing from top to bottom, and through holes in the plurality of capsules are coaxial; when the capsule body is not filled with fluid, the small animal is put into the through hole in the middle of the capsule body and covered with the baffle; the fluid speed control and heating device fills fluid into the bag body through the inlet valve and the inlet pipeline, and flows back to the fluid speed control and heating device through the outlet pipeline and the outlet valve; the sensor unit collects temperature and pressure signals at the through hole of the capsule body and transmits the temperature and pressure signals to the A/D conversion circuit; the A/D conversion circuit converts the analog signal into a digital signal and transmits the digital signal to the controller; the controller adjusts the fluid speed control and the heating temperature of the heating device to the fluid according to the measured temperature signal so as to adjust the temperature of the through hole of the capsule body; the controller controls the injection speed of the fluid through the fluid speed control and heating device according to the measured pressure signal, so as to adjust the pressure at the through hole of the capsule body; the utricule has elasticity, under the unchangeable circumstances of bleeder valve aperture, adjusts the injection velocity of fluid through fluid speed control and heating device and can accurately control the utricule to the pressure of toy, finally realizes the maintenance and the control of pressure to the toy body temperature.

The upper baffle and the lower baffle are connected with the outer housing in a buckling mode.

The fluid velocity control and heating apparatus comprises: the device comprises a heating rod, a fluid conveying pipe, a fluid storage box, a fluid supply valve and a centrifugal pump; wherein the heating rod and the centrifugal pump are connected to the controller; the inlet of the fluid conveying pipe is connected to a drainage pipeline through a drainage valve; the fluid conveying pipe is wound on the heating rod; the outlet of the fluid delivery pipe is connected to the fluid storage box; the bottom of the fluid storage box is connected to the inlet of the centrifugal pump, and the outlet of the centrifugal pump is connected to the inflow pipeline through the inflow valve; a fluid replenishing valve is arranged at the top of the fluid storage box; replenishing fluid to the fluid reservoir through a fluid replenishment valve; the fluid in the capsule body is recovered to the fluid conveying pipe through the drainage pipeline and the drainage valve, and flows through the heating rod to heat the fluid; the controller controls the heating time of the heating rod so as to enable the temperature of the fluid to reach a set value; the heated fluid enters a fluid storage box; the fluid flows from the storage tank to the centrifugal pump, and the controller controls the flow rate of the fluid by controlling the rotating speed of an impeller of the centrifugal pump, so that the temperature and the flow rate of the fluid are controlled.

The centrifugal pump comprises a pump shell and an impeller, and a fluid channel is formed between the pump shell and the impeller; the fluid fills the pump case at first, and the impeller high-speed rotation, the fluid produces high-speed under the centrifugal force effect, and high-speed fluid passes through the fluid passage that the diameter gradually enlarges, realizes the effect of pressure boost, and the controller is through the rotational speed of control impeller, the speed of fluid, and the impeller rotational speed is higher, and the velocity of flow of fluid is faster, otherwise, the velocity of flow of fluid is slower.

The material of the capsule body is one of elastic rubber, latex and polyurethane, so that the damage to the small animals is effectively reduced. The upper baffle and the lower baffle are provided with vent holes, so that the breathing and ventilation requirements of the small animals are met, and enough space is arranged above the bag body, so that the small animals are prevented from suffocating and dying.

The fluid is gas or liquid, air, nitrogen, oil or water.

For medical imaging experiments, the outer housing, the upper baffle and the lower baffle are made of acrylic or wood; for the physiological signal monitoring experiment, acrylic, steel, aluminum, copper or wood is adopted.

The invention also aims to provide a control method of the adaptive-size small animal holding and heat preserving device.

The invention discloses a control method of a self-adaptive body type small animal clamping and heat preserving device, which comprises the following steps:

1) according to the temperature requirement of the experiment, firstly, preheating the fluid in a fluid speed control and heating device;

2) opening an inflow valve, closing a discharge valve, starting a fluid speed control and heating device, and judging whether the pressure reaches a set pressure initial value or not by a controller through a pressure signal from a sensor unit;

3) when the measured pressure is equal to a set initial value, the controller initiates an instruction to the fluid speed control and heating device, opens the drainage valve, and the fluid speed control and heating device fills fluid into the bag body through the drainage valve and the inlet pipeline and flows back to the fluid speed control and heating device through the drainage pipeline and the drainage valve;

4) the sensor unit collects temperature and pressure signals at the through hole of the capsule body and transmits the temperature and pressure signals to the A/D conversion circuit; the A/D conversion circuit converts the analog signal into a digital signal and transmits the digital signal to the controller;

5) the controller adjusts the fluid speed control and the heating temperature of the heating device to the fluid according to the measured temperature signal so as to adjust the temperature of the through hole of the capsule body; the capsule body has elasticity, and the controller can accurately control the pressure at the through hole of the capsule body by controlling the fluid speed and adjusting the injection speed of the fluid through the heating device under the condition that the aperture of the drain valve is not changed according to the measured pressure signal; finally, the control of temperature and pressure is realized;

6) and after the experiment is finished, closing the inflow valve and opening the drainage valve to release the fluid.

The invention has the advantages that:

compared with a rigid fixing device and a clamp, the elastic capsule body effectively reduces the damage to the small animals; meanwhile, the injection speed of the fluid is adjusted in real time through the fluid speed control and heating device, so that accurate pressure clamping on the small animals is realized, on one hand, the small animals with more body sizes can be adapted, and on the other hand, the pressure can be controlled in different areas of the bodies of the small animals in a segmented mode more accurately; the preheating temperature of the fluid is adjusted in real time through the fluid speed control and heating device, so that the experimental temperature can be effectively controlled within a required range; in addition, the device enables the small animal to keep a standing posture, and has wide application prospect for some specially designed experimental devices which need to enable the small animal to be in a standing posture state for a long time; the invention improves the precision of the fixed pressure, realizes the real-time adjustment of the temperature, reduces the damage to the small animals and simplifies the operation complexity of experimenters.

Drawings

FIG. 1 is a schematic view of a first embodiment of the adaptive-size small-animal holding and warming device according to the present invention;

FIG. 2 is a schematic view of an experimental process of a first embodiment of the adaptive-type small-animal holding and warming device according to the present invention;

FIG. 3 is a schematic view of a fluid velocity control and heating device of a first embodiment of the adaptive-type small-animal holding and warming device of the present invention;

FIG. 4 is a schematic view of a bladder of a first embodiment of the adaptive-type small-animal holding and warming device of the present invention when not filled with fluid;

fig. 5 is a schematic view of a second embodiment of the adaptive-size small-animal holding and warming device according to the present invention.

Detailed Description

The invention will be further elucidated by means of specific embodiments in the following with reference to the drawing.