阅读说明：本技术 一种抗皱保湿护肤水及其制备方法 (Anti-wrinkle moisturizing skin care lotion and preparation method thereof ) 是由 胡翠霞 苏学军 关珊 孔梦瑶 聂珊 杨心源 李宛津 于 2019-12-03 设计创作，主要内容包括：本发明涉及日化用品领域,更具体地,本发明提供了一种抗皱保湿护肤水及其制备方法。本发明第一方面提供一种抗皱保湿护肤水,按重量份计,制备原料至少包括1～4份调理剂、8～14份保湿剂、0.2～1份防腐剂、0.05～0.1份pH稳定剂、0.1～0.3份增溶剂、0.02～0.1份增稠剂、0.5～2份抗氧剂、2～7份醇类物质；所述增溶剂选自PEG-40氢化蓖麻油、PEG-60氢化蓖麻油、PEG-80氢化蓖麻油中的一种或几种组合。(The invention relates to the field of daily chemical articles, and particularly provides anti-wrinkle moisturizing lotion and a preparation method thereof. The invention provides anti-wrinkle moisturizing lotion which comprises, by weight, at least 1-4 parts of a conditioner, 8-14 parts of a humectant, 0.2-1 part of a preservative, 0.05-0.1 part of a pH stabilizer, 0.1-0.3 part of a solubilizer, 0.02-0.1 part of a thickener, 0.5-2 parts of an antioxidant and 2-7 parts of an alcohol substance; the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and PEG-80 hydrogenated castor oil.)

1. The anti-wrinkle moisturizing skin lotion is characterized by comprising, by weight, 1-4 parts of a conditioner, 8-14 parts of a humectant, 0.2-1 part of a preservative, 0.05-0.1 part of a pH stabilizer, 0.1-0.3 part of a solubilizer, 0.02-0.1 part of a thickener, 0.5-2 parts of an antioxidant and 2-7 parts of an alcohol substance;

the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and PEG-80 hydrogenated castor oil.

2. The anti-wrinkle moisturizing lotion according to claim 1, wherein the conditioning agent comprises jellyfish extract and schizandrin B.

3. The anti-wrinkle moisturizing lotion according to claim 2, wherein the conditioner further comprises a polypeptide solution.

4. The anti-wrinkle moisturizing toner as claimed in claim 3, wherein the weight ratio of the jellyfish extract to the schisandrin B to the polypeptide solution is 1: (0.05-0.3): (0.001-0.05).

5. The anti-wrinkle moisturizing lotion according to claim 1, wherein the moisturizer is selected from one or more of sodium hyaluronate, allantoin, oat glucan, amino acid, ceramide and mineral oil.

6. The anti-wrinkle moisturizing lotion according to claim 5, wherein the moisturizer comprises oat glucan, allantoin and sodium hyaluronate.

7. The anti-wrinkle moisturizing lotion according to claim 6, wherein the mass ratio of oat glucan to allantoin to sodium hyaluronate is 1: 1: (8-10).

8. The anti-wrinkle moisturizing lotion according to claim 7, wherein the molecular weight of the sodium hyaluronate is 200-400 kDa.

9. The anti-wrinkle moisturizing lotion according to claim 1, wherein the thickener is selected from one or more of sodium carboxymethylcellulose, hydroxyethyl cellulose, magnesium aluminum silicate and carbomer.

10. The preparation method of the anti-wrinkle moisturizing lotion according to any one of claims 1 to 9, characterized by comprising at least the following steps:

(1) heating pure water to 85-90 ℃, and preserving heat for 20-30 min;

(2) cooling the pure water to 35-70 ℃ by introducing cooling water, adding alcohol substances, a thickening agent, a humectant, an antioxidant, a preservative, a conditioning agent, a solubilizer, a pH stabilizer and essence, and stirring and dissolving to obtain a mixed solution;

(3) and cooling the mixed solution to 25-30 ℃ by introducing cooling water, and filtering to obtain the product.

Technical Field

The invention relates to the field of daily chemical articles, and particularly provides anti-wrinkle moisturizing lotion and a preparation method thereof.

Background

Skin aging is a continuous and gradual physiological process that directly affects the appearance and function of the skin. Wrinkles are the result of aging of the skin, as a result of lack of moisture, reduced surface fat, and decreased elasticity of the skin. With the continuous improvement of living standard of people, the anti-aging and wrinkle-removing become the topic of people's attention.

Anti-wrinkle products are emerging on the market today with attractive advertising, but several dozen exclamations are effective. Many skin care products for beautifying and anti-wrinkle can only be absorbed by the surface layer of skin to a great extent, but cannot really enter the dermis layer, so that the purposes of deep renewal and collagen supplement are achieved, and the effects of reducing wrinkles and delaying senescence are achieved.

With the aging, the collagen and the elastic fiber of the facial skin are gradually reduced, and wrinkles are generated, but many beauty anti-wrinkle skin care products can only be absorbed by the surface layer of the skin to a great extent and cannot really enter the dermis. In addition, many anti-wrinkle moisturizing products have the problems of low stability and low transparency, and limit the long-term use of the products.

Disclosure of Invention

In order to solve the technical problems, the first aspect of the invention provides an anti-wrinkle moisturizing lotion, which at least comprises, by weight, 1-4 parts of a conditioner, 8-14 parts of a humectant, 0.2-1 part of a preservative, 0.05-0.1 part of a pH stabilizer, 0.1-0.3 part of a solubilizer, 0.02-0.1 part of a thickener, 0.5-2 parts of an antioxidant and 2-7 parts of an alcohol substance; the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and PEG-80 hydrogenated castor oil.

As a preferred technical scheme of the invention, the conditioner comprises jellyfish extract and schisandrin B.

As a preferred technical scheme of the invention, the conditioning agent also comprises polypeptide solution.

As a preferred technical scheme of the invention, the mass ratio of the jellyfish extract to the schisandrin B to the polypeptide solution is 1: (0.05-0.3): (0.001-0.05).

As a preferable technical scheme of the invention, the humectant is selected from one or a combination of more of sodium hyaluronate, allantoin, oat glucan, amino acid, ceramide and mineral oil.

As a preferable technical scheme, the humectant comprises oat glucan, allantoin and sodium hyaluronate.

According to a preferable technical scheme, the mass ratio of the oat glucan to the allantoin to the sodium hyaluronate is 1: 1: (8-10).

As a preferable technical scheme of the invention, the molecular weight of the sodium hyaluronate is 200-400 kDa.

As a preferable technical scheme of the invention, the thickening agent is selected from one or a combination of more of sodium carboxymethylcellulose, hydroxyethyl cellulose, magnesium aluminum silicate and carbomer.

The second aspect of the invention provides a preparation method of the anti-wrinkle moisturizing lotion, which at least comprises the following steps:

(1) heating pure water to 85-90 ℃, and preserving heat for 20-30 min;

(2) cooling the pure water to 35-70 ℃ by introducing cooling water, adding alcohol substances, a thickening agent, a humectant, an antioxidant, a preservative, a conditioning agent, a solubilizer, a pH stabilizer and essence, and stirring and dissolving to obtain a mixed solution;

(3) and cooling the mixed solution to 25-30 ℃ by introducing cooling water, and filtering to obtain the product.

Has the advantages that: the invention provides an anti-wrinkle moisturizing lotion which can bring effects of reducing wrinkles, tightening skin, replenishing water, moisturizing and delaying aging, and meanwhile, has good stability and can keep good transparency.

Detailed Description

The disclosure may be understood more readily by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, including definitions, will control.

The terms "comprises," "comprising," "includes," "including," "has," "having," "contains," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.

When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted to include the ranges "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.

In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.

In order to solve the technical problems, the first aspect of the invention provides an anti-wrinkle moisturizing lotion, which at least comprises, by weight, 1-4 parts of a conditioner, 8-14 parts of a humectant, 0.2-1 part of a preservative, 0.05-0.1 part of a pH stabilizer, 0.1-0.3 part of a solubilizer, 0.02-0.1 part of a thickener, 0.5-2 parts of an antioxidant and 2-7 parts of an alcohol substance;

the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and PEG-80 hydrogenated castor oil.

In a preferred embodiment, the anti-wrinkle moisturizing lotion is prepared from at least 2 parts by weight of conditioner, 11 parts by weight of humectant, 0.6 part by weight of preservative, 0.07 part by weight of pH stabilizer, 0.2 part by weight of solubilizer, 0.06 part by weight of thickener, 2.2 parts by weight of antioxidant and 4 parts by weight of alcohol.

In a more preferable embodiment, the anti-wrinkle moisturizing lotion further comprises, by weight, 0.1-0.3 parts of essence and 70-90 parts of pure water.

In a more preferred embodiment, the anti-wrinkle moisturizing lotion further comprises 0.2 part of essence and 80 parts of pure water by weight.

<Conditioning agent>

The conditioner comprises jellyfish extract and schisandrin B.

In a preferred embodiment, the conditioning agent further comprises a polypeptide solution.

In a more preferred embodiment, the weight ratio of the jellyfish extract, schisandrin B and the polypeptide solution is 1: (0.05-0.3): (0.1-5); more preferably, the mass ratio of the jellyfish extract to the schisandrin B to the polypeptide solution is 1: 0.17: 2.5.

in a more preferred embodiment, the polypeptide solution comprises acetyl hexapeptide-8 and palmitoyl tripeptide-1.

In a more preferred embodiment, the mass ratio of acetyl hexapeptide-8 to palmitoyl tripeptide-1 is (2-5): 1; more preferably, the mass ratio of the acetyl hexapeptide-8 to the palmitoyl tripeptide-1 is 3: 1.

in a more preferred embodiment, the polypeptide solution is prepared by: acetyl hexapeptide-8 and palmitoyl tripeptide-1 were added to pure water containing 5 wt% glycerol and dissolved by stirring to prepare a 0.01 wt% polypeptide solution.

In a more preferred embodiment, the jellyfish extract is purchased from Guangzhou Reunion New materials science and technology, Inc.

The jellyfish extract is extracted from deep-sea jellyfish, the main component is mucin, the skin moisture loss caused by the external severe environment can be prevented, and the damaged skin can be quickly repaired, probably because of the synergistic effect of collagen, elastin, natural chondroitin and the like; the mucin can restore the elasticity of sensitive skin. The jellyfish extract has the effects of moisturizing and resisting aging, can regulate the barrier function of skin by promoting keratinization, locks nourishing components, can instantly perform infiltration and repair on damaged skin by activated stem cell complexes in jellyfish, and enhances the resistance of skin.

Schisandrin B is the latest anti-free radical substance extracted from Chinese herbal medicine schisandra, is known as 'cleaning of free radicals', can completely remove free radicals and delay aging; the spots are reduced, wrinkles are smoothed, and the elasticity and luster of the skin are enhanced; the degree of cell aging and damage is reduced, and the incidence rate of cell variation is reduced; increasing the immunity of skin. Schisandrin B can make skin smooth and elastic, and has effects of caring skin.

The two biological active peptides, namely acetyl hexapeptide-8 and palmitoyl tripeptide-1, can inhibit the release of the nerve conduction element acetylcholine, reduce the contraction of muscles and promote the generation of new collagen, so that static lines can be smoothed, the generation of dynamic lines and expression lines can be reduced, and the effects of reducing wrinkles, tightening skins and delaying senescence can be achieved.

<Moisture-retaining agent>

The humectant disclosed by the invention is selected from one or a combination of more of sodium hyaluronate, allantoin, oat glucan, amino acid, ceramide and mineral oil.

In a preferred embodiment, the moisturizer comprises oat dextran, allantoin, and sodium hyaluronate.

In a more preferred embodiment, the mass ratio of oat glucan, allantoin and sodium hyaluronate is 1: 1: (8-10); more preferably, the mass ratio of the oat glucan to the allantoin to the sodium hyaluronate is 1: 1: 9.

in a more preferred embodiment, the oat glucan is purchased from sienna bisde biotechnology limited.

In a more preferred embodiment, the sodium hyaluronate HAs a molecular weight of 200-400 kDa and is available from Rein biosciences, Suzhou under the designation RA-HA 04P.

In a more preferred embodiment, the sodium hyaluronate is 0.5 to 1.5 wt% of sodium hyaluronate aqueous solution; more preferably, the sodium hyaluronate is a 1 wt% aqueous solution of sodium hyaluronate.

<Preservative>

The preservative is selected from one or a combination of methyl hydroxybenzoate, phenoxyethanol, methylisothiazolinone, phenyl salicylate and methyl p-hydroxybenzoate.

In a preferred embodiment, the preservative comprises methylparaben and phenoxyethanol.

In a more preferred embodiment, the mass ratio of methylparaben to phenoxyethanol is 1: (0.8 to 1); more preferably, the mass ratio of methyl hydroxybenzoate to phenoxyethanol is 1: 0.9.

<pH stabilizer>

The pH stabilizer is selected from one or a combination of more of monoethanolamine, diethanolamine, triethanolamine, triisopropanolamine and sodium hydroxide.

In a preferred embodiment, the pH stabilizer is triethanolamine.

<Solubilizer>

The present invention relates to a surfactant having solubilizing ability.

In one embodiment, the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil and PEG-80 hydrogenated castor oil; the solubilizer is PEG-40 hydrogenated castor oil, and is purchased from Wuhan New land environmental protection materials GmbH.

<Thickening agent>

The thickening agent is selected from one or a combination of more of sodium carboxymethylcellulose, hydroxyethyl cellulose, magnesium aluminum silicate and carbomer.

In a preferred embodiment, the carbomer is selected from one or more of carbomer 980, carbomer 934 and carbomer 941; the thickener was carbomer 980, purchased from Guangzhou card powder Biotech, Inc.

In the experimental process, the applicant finds that when PEG-40 hydrogenated castor oil and carbomer 980 are added into the system, the prepared skin moisturizer has better stability and can keep better transparency.

<Antioxidant agent>

The antioxidant is selected from one or a combination of more of nicotinamide, persimmon leaf polyphenol, ascorbic acid and vitamin E.

In a preferred embodiment, the antioxidant is niacinamide.

<Alcohol substance>

The alcohol substance of the present invention is a compound having a hydroxyl group bonded to a carbon on a side chain of a hydrocarbon group or a benzene ring in a molecule.

In one embodiment, the alcohol is selected from one or more of ethanol, glycerol, propylene glycol, diglycerol, 1, 3-butylene glycol, xylitol, sorbitol, and polyethylene glycol.

In a preferred embodiment, the alcohol species include ethanol, glycerol, and propylene glycol.

In a more preferred embodiment, the mass ratio of ethanol, glycerol and propylene glycol is 1: (10-12): (10-12); more preferably, the mass ratio of the ethanol to the glycerol to the propylene glycol is 1: 11: 11.

<essence>

The essence of the invention is a substance which can generate pleasant smell and can cover the smell of a product substrate.

In one embodiment, the essence is selected from one or more of convallaria majalis essence, cymbidium alba essence, lilac essence and basil essence.

In a preferred embodiment, the essence is convallaria majalis essence purchased from Tianjin Xinnuson biotechnology, Inc.

The second aspect of the invention provides a preparation method of the anti-wrinkle moisturizing lotion, which at least comprises the following steps:

(1) heating pure water to 85-90 ℃, and preserving heat for 20-30 min;

(2) cooling the pure water to 35-70 ℃ by introducing cooling water, adding alcohol substances, a thickening agent, a humectant, an antioxidant, a preservative, a conditioning agent, a solubilizer, a pH stabilizer and essence, and stirring and dissolving to obtain a mixed solution;

(3) and cooling the mixed solution to 25-30 ℃ by introducing cooling water, and filtering to obtain the product.

In a preferred embodiment, the preparation method of the anti-wrinkle moisturizing lotion at least comprises the following steps:

(1) heating pure water to 85-90 ℃, and preserving heat for 20-30 min;

(2) cooling pure water to 60-70 ℃ by introducing cooling water, adding glycerol, carbomer 980, allantoin, nicotinamide, methylparaben and schisandrin B, and stirring for dissolving to obtain a first mixed solution;

(3) cooling the first mixed solution to 40-50 ℃ by introducing cooling water, adding sodium hyaluronate, oat glucan, ethanol, PEG-40 hydrogenated castor oil, triethanolamine, phenoxyethanol and essence, and stirring for dissolving to obtain a second mixed solution;

(4) cooling the second mixed solution to 35-40 ℃ by introducing cooling water, adding the jellyfish extract and the polypeptide solution, and stirring for dissolving to obtain a third mixed solution;

(5) and cooling the third mixed solution to 25-30 ℃ by introducing cooling water, and filtering by using 2 layers of 200-mesh nylon filter cloth to obtain the composite material.