阅读说明：本技术 一种防抖手持式oct探头 (Anti-shake hand-held type OCT probe ) 是由 谢林春 杨建龙 施鹏程 黄昕 胡衍 杨燕鹤 刘江 于 2019-10-30 设计创作，主要内容包括：本发明涉及眼底光学相干断层扫描成像技术领域,具体涉及一种防抖手持式OCT探头。包括：光路模块,设有壳体、设于所述壳体内的成像光路和照明光路；固定支架,用于安装所述光路模块；稳定器,设有用于装配所述固定支架的支撑托板。上述技术方案中,将所述光路模块与所述稳定器相结合,通过所述稳定器消除光路模块在数据采集过程中的人为抖动产生的图像运动伪影偏差。(The invention relates to the technical field of fundus optical coherence tomography imaging, in particular to an anti-shake handheld OCT probe. The method comprises the following steps: the light path module is provided with a shell, and an imaging light path and an illumination light path which are arranged in the shell; the fixed bracket is used for mounting the light path module; and the stabilizer is provided with a supporting plate for assembling the fixed support. In the above technical solution, the light path module is combined with the stabilizer, and the stabilizer eliminates an image motion artifact deviation caused by artificial jitter of the light path module in a data acquisition process.)

1. An anti-shake handheld OCT probe, comprising:

the light path module comprises a shell, an imaging light path and an illumination light path, wherein the imaging light path and the illumination light path are arranged in the shell;

the fixed bracket is used for mounting the light path module;

and the stabilizer is provided with a supporting plate for assembling the fixed support.

2. The anti-shake handheld OCT probe of claim 1, wherein:

the stabilizer also comprises a controller, a pitching shaft, a rolling shaft and a course shaft;

the controller controls the course shaft to drive the supporting plate to rotate on a first plane, controls the pitching shaft to drive the supporting plate to rotate on a second plane, and controls the transverse roller to drive the supporting plate to rotate on a third plane;

the first plane, the second plane and the third plane are vertical to each other.

3. An anti-shake hand-held OCT probe according to claim 2, wherein:

the stabilizer further includes a gyroscope for detecting a positional deviation;

and the controller controls the pitching shaft, the rolling shaft and the course shaft to perform reverse position compensation according to the position deviation detected by the gyroscope.

4. An anti-shake hand-held OCT probe according to claim 3, wherein:

the illumination light path comprises an illumination light source, an ocular lens, a light splitter and a display screen;

and the illuminating light emitted by the illuminating light source towards the test position is reflected at the test position and then passes through the eye lens and the beam splitter to irradiate the display screen.

5. An anti-shake hand-held OCT probe according to claim 4, wherein:

the imaging light path comprises a laser collimator, a focusing lens, a scanning galvanometer, a lens, the beam splitter and the ocular lens;

the imaging light emitted by the laser collimator enters the scanning galvanometer after being subjected to focusing processing by the focusing lens, is reflected by the scanning galvanometer to the lens to be emitted to the optical splitter, and passes through the ocular lens after being reflected by the optical splitter to enter the test position.

6. An anti-shake hand-held OCT probe according to claim 5, wherein:

the lens and the eye lens are achromatic double-cemented lenses.

7. An anti-shake hand-held OCT probe according to claim 5, wherein:

the light splitter is a short-wave-pass dichroic mirror.

8. An anti-shake hand-held OCT probe according to claim 5, wherein:

the focal length of the focusing lens is adjusted in a range of-77 to + 77.

9. An anti-shake hand-held OCT probe according to claim 3, wherein:

the iris camera control system is characterized by further comprising an iris camera arranged at the test position and an iris camera control panel in communication connection with the iris camera.

10. An anti-shake hand-held OCT probe according to claim 3, wherein:

the stabilizer is in communication connection with the iris camera control panel;

the stabilizer tracks a tracking object locked by the iris control panel.

Technical Field

The invention relates to the technical field of fundus optical coherence tomography imaging, in particular to an anti-shake handheld OCT probe.

Background

Optical Coherence Tomography (OCT) is a low-loss, high-resolution, non-invasive imaging modality. The method utilizes the basic principle of a weak coherent light interferometer to detect back reflection or several scattering signals of incident weak coherent light at different depth levels of biological tissues, and two-dimensional or three-dimensional structural images of the biological tissues can be obtained by scanning. The method can be used for acquiring high-resolution images in human ophthalmology, and is widely applied to ophthalmology diagnosis and treatment of various diseases, such as retinal vascular diseases, glaucoma, idiopathic macular foveal capillary vasodilation, diabetic retinopathy, choroidal neovascularization, optic neuritis and other various ophthalmology diseases.

However, most commercial ophthalmic OCT devices are bulky and are mounted on a table for data acquisition, which requires the patient or subject to sit upright in front of the machine device and hold the eye open for several minutes to complete the image acquisition. It is particularly difficult to acquire data of special patients such as anesthesia patients, severe patients in bed, infants, retinopathy premature infants and the like.

In order to improve operability and application range of the OCT system, various handheld OCT probes have been developed in the form of commercial products in recent years for research and clinical applications (for example, a handheld OCT probe and an OCT measurement system disclosed in utility model patent No. CN202699100U, publication No. 2013, 1 month and 30 days). Most of the handheld probes select a handheld mode, and mechanical adjustment and alignment are performed by using arms, because human bodies have uncontrollable factors, a data collector has certain jitter in the operation process or the data collector cannot keep a good static state such as an infant, and a data collecting signal becomes fuzzy or is difficult to collect, and imaging problems such as image motion artifacts are easily generated.

Disclosure of Invention

The invention provides an anti-shake handheld OCT probe aiming at the defects and shortcomings that the existing OCT probe can not effectively solve hand shake in the data acquisition process, can only depend on an arm to perform mechanical adjustment for alignment and focusing, and can not effectively eliminate shake, motion artifacts and the like in the data acquisition process, and the anti-shake handheld OCT probe is characterized by comprising the following components:

the light path module comprises a shell, an imaging light path and an illumination light path, wherein the imaging light path and the illumination light path are arranged in the shell;

the fixed bracket is used for mounting the light path module;

and the stabilizer is provided with a supporting plate for assembling the fixed support.

In the above technical solution, the light path module is combined with the stabilizer, and the stabilizer eliminates an image motion artifact deviation caused by artificial jitter of the light path module in a data acquisition process.

Preferably, the stabilizer further comprises a controller, a pitch axis, a roll axis, and a heading axis; the controller controls the course shaft to drive the supporting plate to rotate on a first plane, controls the pitching shaft to drive the supporting plate to rotate on a second plane, and controls the transverse roller to drive the supporting plate to rotate on a third plane; the first plane, the second plane and the third plane are vertical to each other. The controller coordinates the pitch axis, the roll axis, and the heading axis to maintain stability of the support pallet.

Preferably, the stabilizer further includes a gyroscope for detecting a positional deviation; and the controller controls the pitching shaft, the rolling shaft and the course shaft to perform reverse position compensation according to the position deviation detected by the gyroscope.

Preferably, the illumination light path comprises an illumination light source, an ocular lens, a beam splitter and a display screen; and the illuminating light emitted by the illuminating light source towards the test position is reflected at the test position and then passes through the eye lens and the beam splitter to irradiate the display screen. The display screen can display static or dynamic pictures and is used for attracting the attention of a tested user when data are collected, and the tested target can be conveniently aligned and focused.

Preferably, the imaging optical path comprises a laser collimator, a focusing lens, a scanning galvanometer, a lens, the beam splitter and the ocular lens; the imaging light emitted by the laser collimator enters the scanning galvanometer after being subjected to focusing processing by the focusing lens, is reflected by the scanning galvanometer to the lens to be emitted to the optical splitter, and passes through the ocular lens after being reflected by the optical splitter to enter the test position.

Preferably, the lens and the eyepiece lens are achromatic double cemented lenses.

Preferably, the light splitter is a short-wave-pass dichroic mirror.

Preferably, the focal length of the focusing lens is adjusted in a range of-77 mm to +77 mm.

Preferably, the device also comprises an iris camera arranged at the test position and an iris camera control panel in communication connection with the iris camera.

Preferably, the stabilizer is in communication connection with the iris camera control panel; the stabilizer tracks a tracking object locked by the iris control panel. The probe can automatically track and adjust along with the movement of eyeballs, and the problems that the focusing is difficult and the image is difficult to obtain due to the fact that the object to be measured is continuously shaken in conventional equipment can be solved.

The invention has the following beneficial effects:

1. the light path module used by the invention is combined with the stabilizer, the stabilizer has an automatic reverse compensation function, can eliminate shaking conditions of various sizes in the data acquisition process, has an automatic balancing anti-shaking function, and eliminates image motion artifact deviation generated by artificial shaking in the data acquisition process.

2. The iris camera used by the invention is combined with the stabilizer, has an automatic tracking and following function, and the probe can automatically track and adjust along with the movement of eyeballs, so that the problems of difficult focusing and difficult image acquisition caused by continuous shaking of the measured object in conventional equipment can be solved.

3. The handheld design of the invention ensures that the equipment using the probe is not limited by the field and has good environmental adaptability.

4. The invention adopts the display screen to display different static markers or small object dynamic pictures, and the images are flexible and changeable, thereby meeting the requirements of different types of patients to be tested.

Drawings

FIG. 1 is a schematic diagram of an imaging system of an anti-shake hand-held OCT probe of the invention;

FIG. 2 is a schematic structural diagram of an anti-shake stabilizer used in the present invention;

figure 3 is a side view of an embodiment of the anti-shake hand-held OCT probe design of the present invention.

Detailed Description

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. Unless otherwise defined, all terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that the conventional terms should be interpreted as having a meaning that is consistent with their meaning in the relevant art and this disclosure. The present disclosure is to be considered as an example of the invention and is not intended to limit the invention to the particular embodiments.

Fig. 1, fig. 2 and fig. 3 are schematic structural diagrams of an embodiment of an anti-shake hand-held OCT probe according to the present invention. The optical path module 100 comprises a housing 110, and the optical path module 100 comprises a stabilizer 200, and the optical components involved in the whole optical path are fixed in the housing 110. The housing 110 is mounted to the stabilizer 200 by a fixing bracket 301. The probe equipment of this embodiment is easily assembled and is dismantled, and the structure is compacter, portable.

The optical components in the optical path module 100 include a laser collimator 101, a focusing lens 102, a scanning galvanometer 103, a lens 104, a beam splitter 105, a display screen 106, an ocular lens 107, an illumination light source 108, and an iris camera 109, which are used to form an imaging optical path and an illumination optical path. The stabilizer 200 includes a control module, an iris camera 109, and an iris camera control panel 302.

The illumination light source 108 is an LED white light source, and irradiates an eyeball of the user to be measured from the side, and enters the fundus through the pupil to form reflected light.

The adjustable focus lens 102 is an electronic adjustable focus lens which can be changed from a concave surface to a convex surface rapidly after being electrified, and the focal length of the adjustable focus lens is adjusted between-77 mm and 77 mm.

The scanning galvanometer 103 is a two-dimensional mechanical scanning galvanometer.

The ocular lens 107 is an achromatic doublet of focal length 30 and the lens 104 is an achromatic doublet of focal length 50.

The beam splitter 105 uses a dichroic mirror, such as a short-wave pass dichroic mirror, with a cut-off wavelength of 650 nm. 95% or more of light having a wavelength of 650nm or more can be reflected, and 95% or more of light having a wavelength of 650nm or less can be transmitted.

The display screen 106 is a miniature electronic display screen, and can display different static markers or dynamic pictures of small objects. When the probe is used for data acquisition, the image can be played as required to attract the attention of a tested user, and the alignment and focusing during testing are facilitated.

And the iris camera 109 is used for displaying the focused object image in real time so as to automatically track and follow the moving object. The iris camera 109 is connected to the iris camera control panel 302 through a data line so that the movement of the iris camera control panel 302 does not affect the movement of the iris camera 109.

The housing 110 is printed in 3D, the optical devices are assembled and fixed in the housing 110, and the housing 110 has mounting holes for mounting on the support plate 202 of the stabilizer 200.

Fig. 1 is a schematic diagram of an imaging system of the anti-shake hand-held OCT probe of the present invention:

the illumination light path comprises an illumination light source 108, an ocular lens 107, a beam splitter 105 and a display screen 106, and illumination light emitted by the illumination light source 108 towards the test position is reflected at the test position and then passes through the beam splitter 105 through the ocular lens 107 to be irradiated to the display screen 106. Specifically, in the present embodiment, the white light emitted from the illumination light source 108 toward the test position irradiates the surface of the eyeball E of the tested person to generate reflected light, the reflected light passes through the ocular lens 107 and enters the light splitter 105 after being amplified, the light splitter 105 can transmit the white light completely, and the light irradiates the display screen 106.

The imaging optical path comprises a laser collimator 101, a focusing lens 102, a scanning galvanometer 103, a lens 104, a beam splitter 105 and an ocular lens 107. Imaging light emitted by the laser collimator 101 enters the scanning galvanometer 103 after being subjected to focusing processing by the focusing lens 102, is reflected by the scanning galvanometer 103 to the lens 104 and then emitted to the light splitter 105, and passes through the ocular lens 107 after being reflected by the light splitter 105 and enters a test position. In this embodiment, the imaging light path employs infrared light with a wavelength of 800-850 nm. The infrared light passes through the focusing lens 102 after being collimated and corrected by the laser collimator 101, different focal lengths of the focusing lens 102 are adjusted according to actual needs, infrared light beams subjected to focusing are reflected by the scanning galvanometer 103 and then enter the lens 104, the light beams pass through the light splitter 105, the light splitter (dichroic mirror) can carry out total reflection on infrared light with the wavelength of 800-850 nm, and the light beams pass through the eye lens 107 after being totally reflected to the eye lens 107 and enter an eyeball E of a tested person located at a testing position.

Fig. 2 is a schematic view of a stabilizer used in the present invention. The stabilizer 200 of the present embodiment has an automatic anti-shake function. Including a rocker 201, a support plate 202, a pitch axis 203 rotating about the Y-axis, a roll axis 204 rotating about the X-axis, a yaw axis 205 rotating about the Z-axis, a controller (not shown), a gyroscope (not shown). A motor is respectively arranged in the roll shaft 204, the pitch shaft 203 and the heading shaft 205 of the stabilizer and respectively controls the movement in three directions of XYZ correspondingly. When the hand shakes or the measured person shakes to cause the spatial position to change in the data acquisition process of the probe, the three motors can perform reverse position compensation, correct the inclination of the picture, reduce and filter the shaking problem in the acquisition process, and the auxiliary device is used for shooting a tool for stabilizing images. The controller is electrically connected with the three motors respectively, so that the controller can control the course shaft to drive the supporting plate to rotate on a first plane (namely to rotate around the Z axis of a rectangular coordinate system), control the pitch shaft to drive the supporting plate to rotate on a second plane (namely to rotate around the Y axis of the rectangular coordinate system), and control the transverse roller to drive the supporting plate to rotate on a third plane (namely to rotate around the X axis of the rectangular coordinate system).

Fig. 3 is a schematic structural diagram of an anti-shake hand-held OCT probe according to the present invention. The probe design is composed of a light path module 100, a stabilizer 200, a fixed bracket 301 and an iris camera control panel 302 connected with an iris camera 109. The specific working process is as follows:

the optical path module 100 is mounted on a fixing bracket 301, and the fixing bracket 301 is assembled on the support plate 202 of the stabilizer 200 and adjusted to be well balanced. The iris control panel 302 is connected with the stabilizer 200 through Bluetooth, a picture in front of the ocular lens 107 can be transmitted to the iris camera control panel 302 through the iris camera 109 installed at the test position, and the rocker 201 on the stabilizer 200 adjusts the rotation of the light path module 100 installed on the support plate 202 in all directions.

The connected stabilizer 200 is held by hand, the rocker 201 of the stabilizer is adjusted, and the ocular lens 107 is aligned with the eyeball M of the detected person. In the data acquisition process, the three motors of the stabilizer 200 drive the balance shafts (i.e., the pitch shaft, the roll shaft and the course shaft) to increase stability, and drive the light path module 100 to acquire data of the target to be detected, so as to eliminate instability caused by hand shake of an operator.

The eyeball M of the subject is frame-grabbed on the screen of the iris camera control panel 302 of the connected stabilizer 200 to lock the tracking object. The stabilizer 200 automatically tracks the movement of the following object according to the acquired reference object, so that the stabilizer can track the tracking object locked by the iris control panel 302. The eyeball M of the tested person moves left and right or the head shakes, the probe and the iris camera 109 automatically track and move together, and then data acquisition of different requirements can be completed according to requirements.

Although embodiments of the present invention have been described, various changes or modifications may be made by one of ordinary skill in the art within the scope of the appended claims.