阅读说明：本技术 一种新型静电纺丝给药装置 (Novel electrostatic spinning dosing device ) 是由 冯波 石九曜 高明 赵奇 苏丹 丁想 于 2019-12-05 设计创作，主要内容包括：一种新型静电纺丝给药装置属于给药装置技术领域,尤其涉及一种新型给药静电纺丝装置。本发明提供一种使用效果好的新型静电纺丝给药装置。本发明包括外壳、供液给药系统、气体发生装置和高压电源产生装置17,其特征在于外壳上设置有出气口10、进气口9和喷丝头14,进气口9通过气体发生装置与出气口10相连,出气口10设置在喷丝头14的外周；高压电源产生装置与喷丝头14的供电端口相连,供液给药系统与喷丝头14的给药输入端口相连。(The utility model provides a novel electrostatic spinning device of dosing belongs to the technical field of dosing, especially relates to a novel electrostatic spinning device of dosing. The invention provides a novel electrostatic spinning drug delivery device with a good using effect. The invention includes the outer cover, supplies liquid medicine feeding system, gas generator and high voltage power supply to produce the device 17, characterized by that there are air outlets 10, air inlets 9 and spinnerets 14 on the outer cover, the air inlet 9 couples to air outlet 10 through the gas generator, the air outlet 10 is set up in the periphery of the spinnerets 14; the high-voltage power supply generating device is connected with a power supply port of the spinneret 14, and the liquid supply and drug delivery system is connected with a drug delivery input port of the spinneret 14.)

1. A novel electrostatic spinning drug delivery device comprises a shell, a liquid supply drug delivery system, a gas generating device and a high-voltage power supply generating device (17), and is characterized in that the shell is provided with a gas outlet (10), a gas inlet (9) and a spinning nozzle (14), the gas inlet (9) is connected with the gas outlet (10) through the gas generating device, and the gas outlet (10) is arranged at the periphery of the spinning nozzle (14);

the high-voltage power supply generating device is connected with a power supply port of the spinneret (14), and the liquid supply and drug delivery system is connected with a drug delivery input port of the spinneret (14).

2. The novel electrostatic spinning drug delivery device as claimed in claim 1, characterized in that the liquid supply drug delivery system comprises an injector (15) for supplying the spinning precursor liquid to the spinneret (14) and a liquid supply driving part (16) for driving the injector (15).

3. The novel electrostatic spinning drug delivery device is characterized in that the liquid supply driving part (16) adopts a linear driving motor, and a push rod of the linear driving motor is connected with a piston of the injector (15); and the shell is provided with a forward and backward key (23) for controlling a push rod of the linear driving motor.

4. The novel electrostatic spinning drug delivery device according to claim 2, characterized in that the injector (15) is connected with the inner wall of the shell through a clamping groove, a liquid exchange cover (1) is arranged above the injector (15), and the liquid exchange cover (1) is connected with the shell in a clamping manner.

5. The novel electrostatic spinning drug delivery device according to claim 4, characterized in that the liquid changing cover (1) is provided with a transparent observation window (13) for observing the spinning precursor medicament liquid in the injector (15).

6. The novel electrospinning drug delivery device of claim 1, wherein the housing is provided with an infrared target (11), and the infrared target (11) is disposed below the spinneret (14).

7. The novel electrospinning drug delivery device of claim 1, wherein the spinneret (14) is a metal capillary spinneret.

8. The novel electrostatic spinning drug delivery device as claimed in claim 1, characterized in that the air outlet (10) is provided in a plurality and is distributed uniformly along the circumference of the spinneret (14).

9. The novel electrostatic spinning drug delivery device according to claim 1, characterized in that the outer shell comprises a transverse shell and a transverse lower shell, a vertical middle shell is connected between the upper shell and the lower shell, a vertical rear shell is connected between the rear parts of the upper shell and the lower shell, the gas outlet (10) is arranged at the front end of the upper shell, the gas inlet (9) is arranged at the front part of the lower shell, the front end of the middle shell is provided with an infrared target start button (3), the upper shell is provided with a wind volume control knob (5) of the gas generation device and a control button (12) for controlling the liquid supply speed of the liquid supply and drug delivery system, the rear end of the lower shell is provided with a power main switch (21), and the front end of the middle shell is.

10. The novel electrostatic spinning drug delivery device as claimed in claim 1, characterized in that the housing is provided with a patient lead connector (29), and the patient lead connector (29) is connected with the high voltage power supply generating device (17).

Technical Field

The invention belongs to the technical field of drug delivery devices, and particularly relates to a novel drug delivery electrostatic spinning device.

Background

The electrostatic spinning is one of the simplest and most efficient methods for preparing the nano fibers, and compared with the traditional nano material preparation technology, the method has the advantages of simple processing device, wide raw material source, low spinning cost, large-scale preparation and the like. In recent years, the method has been widely researched and reported at home and abroad. The nanofiber prepared by processing by the electrostatic spinning technology has the excellent characteristics of high specific surface area, larger length/diameter ratio, unique physical and chemical properties and the like, and shows great application potential in the fields of biological tissue engineering, wound auxiliary materials, filtration protection, drug sustained release, flexible devices and the like. The electrostatic spinning principle is very simple, and is briefly described as follows: under the action of a high-voltage electric field, polymer solution or melt at the spinning nozzle is sprayed out under the action of electrostatic field force to form jet flow, the jet flow is split and stretched in the falling process, and meanwhile, the solvent is volatilized to form nano fibers which are solidified and molded and deposited on the collecting electrode. The using effect of the existing electrostatic spinning device is yet to be further improved.

Disclosure of Invention

The invention aims at the problems and provides a novel electrostatic spinning drug delivery device with good use effect.

In order to achieve the purpose, the invention adopts the following technical scheme that the invention comprises a shell, a liquid supply and drug delivery system, a gas generation device and a high-voltage power supply generation device 17, and is characterized in that the shell is provided with a gas outlet 10, a gas inlet 9 and a spinning nozzle 14, wherein the gas inlet 9 is connected with the gas outlet 10 through the gas generation device, and the gas outlet 10 is arranged at the periphery of the spinning nozzle 14;

the high-voltage power supply generating device is connected with a power supply port of the spinneret 14, and the liquid supply and drug delivery system is connected with a drug delivery input port of the spinneret 14.

As a preferable mode, the liquid supply system of the present invention includes an injector 15 for supplying the spinning precursor liquid to the spinneret 14, and a liquid supply driving section 16 for driving the injector 15.

As another preferred scheme, the liquid supply driving part 16 adopts a linear driving motor, and a push rod of the linear driving motor is connected with a piston of the injector 15.

As another preferable scheme, the housing of the present invention is provided with a forward/backward button 23 for controlling a push rod of the linear driving motor.

As another preferred scheme, the injector 15 is connected with the inner wall of the shell through a clamping groove, the liquid changing cover 1 is arranged above the injector 15, and the liquid changing cover 1 is connected with the shell in a clamping mode.

As another preferred scheme, a transparent observation window 13 for observing the spinning precursor medicament liquid in the injector 15 is arranged on the liquid changing cover 1.

In another preferred embodiment, the housing of the present invention is provided with an infrared target 11, and the infrared target 11 is disposed below the spinneret 14.

As another preferable mode, the overlapping distance of the infrared targets 11 of the present invention is 20 CM.

As another preferred embodiment, a metal capillary spinneret is used as the spinneret 14 of the present invention.

As another preferred scheme, the gas generating device of the invention adopts a gas pump 24.

In another preferred embodiment, the air outlets 10 are provided in a plurality and are uniformly distributed along the circumference of the spinneret 14.

As another preferred scheme, the shell comprises a transverse shell and a transverse lower shell, a vertical middle shell is connected between the upper shell and the lower shell, a vertical rear shell is connected between the rear parts of the upper shell and the lower shell, the air outlet 10 is arranged at the front end of the upper shell, the air inlet 9 is arranged at the front part of the lower shell, the front end of the middle shell is provided with an infrared target starting button 3, the upper shell is provided with an air volume control knob 5 of the gas generating device and a control button 12 for controlling the liquid supply speed of the liquid supply and drug delivery system, the rear end of the lower shell is provided with a power supply main switch 21, and the front end of the middle shell is.

As another preferred scheme, the housing of the present invention is provided with a patient lead connector 29, and the patient lead connector 29 is connected with the high voltage power generating device 17.

As another preferable mode, the housing of the present invention is provided with a charging port 22 for charging the high-voltage power generating device 17.

As another preferable scheme, the shell of the invention is provided with charging indicator lamps 6 and 8 and an electric quantity alarm lamp 7.

As another preferred scheme, the infrared target 11 and the electric quantity alarm portion of the present invention include an LM3914 chip U1, a pin 5 of U1 is connected to an adjustment end of a rheostat RV1, one end of RV1 is connected to one end of a resistor R3, one end of a resistor R2, a pin 8 of U1, a pin 2 of U1, a first end of a switch SW1, and a first end of a switch SW2, the other end of R2 is connected to pins 6 and 7 of U2, the other end of R2 is connected to a pin 4 of U2, and the other end of RV2 is connected to a pin 3 of U2, an anode of a diode D2, an anode of the diode D2, a second end of the SW2, a pin 9 of the U2, and a second end of the SW 2;

the cathode of the diode D1, the cathode of the diode D2, the cathode of the diode D3, the cathode of the diode D4, the cathode of the diode D5, the cathode of the diode D6, the cathode of the diode D7, the cathode of the diode D8, the cathode of the diode D9 and the cathode of the diode D10 are correspondingly connected with pins 10-18 and 1 of the U1 respectively;

the third end of the SW1 is connected with the negative electrode of a 12V battery BAT1, and the positive electrode of the BAT1 is connected with the fourth end of the SW 1;

the third terminal of SW2 is connected to the anode of diode D11, the anode of diode D12, the cathode of D11 and the cathode of D12 are connected to the fourth terminal of SW 2.

Secondly, the high-voltage power supply generation device 17 comprises a 555 chip, wherein 4 pins of the 555 chip are respectively connected with one end of a resistor R4 and 8 pins of the 555 chip, the other end of R4 is respectively connected with a first end of a switch SW1, one end of a resistor R3, a pin 7 of the 555 chip and one end of the primary side of a transformer TR1, the other end of the primary side of the TR1 is respectively connected with a collector of an NPN triode Q2 and a collector of an NPN triode Q1, an emitter of the Q2 is respectively connected with a second end of a SW1, a pin 1 of the 555 chip, one end of a capacitor C2, one end of a resistor R2, one end of a;

the base of Q2 is connected with the emitter of Q1 and the other end of R2, the base of Q1 is connected with pin 3 of U1 through resistor R1, the other end of R3 is connected with pin 2 of 555 chip, pin 6 of 555 chip and the other end of C2, the third end of SW1 is connected with the positive pole of BAT1, the negative pole of BAT1 is connected with the fourth end of SW 1; the other end of the C1 is connected with the anode of a diode D1, and the cathode of D1 is connected with the other end of the secondary side of the TR 1.

In addition, the liquid feeding and drug administration system and the gas generating device of the invention comprise a first NE555 chip and a second NE555 chip, wherein 4 pins of the first NE555 chip are respectively connected with one end of a resistor R1, 8 pins of the first NE555 chip, a first end of a switch SW1, one end of a resistor R3, 4 pins of the second NE555 chip, 8 pins of the second NE555 chip, a cathode of a diode D6 and one end of a second motor, the other end of the second motor is respectively connected with a D6 anode, an NPN triode Q2 collector, a cathode of a diode D3 and a first end of a switch SW2, a base of the Q2 is connected with a 3 pin of the second NE555 chip through a resistor R4, a 6 pin of the second NE555 chip is respectively connected with a 2 pin of the second NE555 chip, one end of a capacitor C4 and an adjusting end of a rheostat RV2, and the other end of C4 is respectively connected with a 1 pin, an emitter of the Q2, an emitter of the second NE 2, a second end of the SW1, a 1 pin of the;

one end of RV2 is connected with the anode of diode D4, the cathode of D4 is connected with the other end of resistor R3, the anode of diode D5 and the 7 pin of the second NE555 chip, the 5 pin of the second NE555 chip is grounded through capacitor C5;

the pin 5 of the first NE555 chip is grounded through a capacitor C2, the base electrode of the Q1 is connected with the pin 3 of the first NE555 chip through a resistor R2, the collector electrode of the Q1 is respectively connected with the anode of the D3 and the second end of the SW2, the third end of the SW2 is respectively connected with the fourth end of the SW2 and one end of the first motor, and the other end of the first motor is respectively connected with the fifth end of the SW2 and the sixth end of the SW 2;

the other end of the C1 is respectively connected with a pin 2 of the first NE555 chip, a pin 6 of the first NE555 chip and an adjusting end of a rheostat RV1, one end of the RV1 is connected with the anode of a diode D1, the other end of the RV1 is connected with the cathode of a diode D2, and the cathode of the D1 is respectively connected with the other end of the R1 and the pin 7 of the D2 anode of the first NE555 chip;

the third terminal of SW1 is connected to the positive electrode of battery B1, and the negative electrode of B1 is connected to the fourth terminal of SW 1.

The invention has the beneficial effects.

The air outlet 10 of the invention is arranged at the periphery of the spinning nozzle 14, and the air outlet 10 discharges to form directional air flow, thereby realizing directional drug delivery.

Drawings

The invention is further described with reference to the following figures and detailed description. The scope of the invention is not limited to the following expressions.

FIG. 1: the appearance of the device is schematic.

FIG. 2: the internal mechanism of the device is shown schematically.

FIG. 3: the spinning nozzle of the invention is structurally schematic.

FIG. 4: the device of the invention has another angle and appearance schematic diagram.

FIG. 5: the invention relates to a circuit schematic diagram of an electric quantity target device.

FIG. 6: the electrical structure of the invention.

FIG. 7: the invention relates to a high-voltage module circuit schematic diagram.

FIG. 8: the invention discloses a circuit schematic diagram of a propulsion orientation device.

In FIGS. 1-4: 1-replacing the liquid cover; 2-a charging seat; 3-infrared target start button; 4-start button; 5-air volume adjusting button; 6-charging display green light; 7-electric quantity warning light; 8-charging display red light; 9-an air inlet; 10-air outlet; 11-an infrared target; 12-motor propulsion speed control button; 13-a transparent observation window; 14-a spinneret; 15-a syringe; 16-a linear push motor; 17-a high voltage power generating device; 18-a push motor controller; 19-a charging-stand battery; 20-a floor shield; 21-power master switch; 22-a charging port; 23-forward and backward keys; 24-a miniature air pump; 25-a gas delivery conduit; 26-air pump controller; 27-a metal dome; 28-an outlet pipe; 29-patient lead interface.

Detailed Description

As shown in the figure, the invention comprises a shell, a liquid supply and drug delivery system, a gas generating device and a high-voltage power supply generating device 17, wherein the shell is provided with a gas outlet 10, a gas inlet 9 and a spinneret 14, the gas inlet 9 is connected with the gas outlet 10 through the gas generating device, and the gas outlet 10 is arranged at the periphery of the spinneret 14;

the high-voltage power supply generating device is connected with a power supply port of the spinneret 14, and the liquid supply and drug delivery system is connected with a drug delivery input port of the spinneret 14.

The liquid supply system includes an injector 15 for supplying a spinning precursor liquid to the spinneret 14 and a liquid supply driving section 16 for driving the injector 15.

The liquid supply driving part 16 adopts a linear driving motor, and a push rod of the linear driving motor is connected with a piston of the injector 15.

The housing is provided with a forward and backward push button 23 for controlling the push rod of the linear drive motor.

The injector 15 is connected with the inner wall of the shell through a clamping groove, the liquid changing cover 1 is arranged above the injector 15, and the liquid changing cover 1 is connected with the shell in a clamping mode.

The outlet of the barrel of injector 15 is linked to spinneret 14. When the device is used, the liquid changing cover 1 of the gun body shell is opened firstly, the syringe 15 is taken out, the spinning precursor medicament liquid is added into the syringe 15, the syringe 15 is put back to the shell for fixing, and then the liquid changing cover 1 is closed.

And a transparent observation window 13 for observing the spinning precursor medicament liquid in the injector 15 is arranged on the liquid changing cover 1.

The shell is provided with an infrared target 11, and the infrared target 11 is arranged below the spinning nozzle 14. The infrared target 11 is adopted for positioning, the two-point coincidence is an effective spinning administration distance, the coincidence distance is 20CM, effective spinning administration can be carried out on multiple points along with the movement of the gun body, the wound of a patient is not contacted, and unnecessary infection and adverse reaction are avoided.

The coincidence distance of the infrared targets 11 is 20 CM.

The spinneret 14 is a metal capillary spinneret.

The gas generating device adopts a gas pump 24.

The air outlets 10 are distributed uniformly along the circumference of the spinneret 14. The central axis of the circle enclosed by the air outlet 10 coincides with the central axis of the spinneret 14.

The shell includes horizontal shell and horizontal inferior valve, and the epitheca is connected with vertical mesochite with the inferior valve middle part, and the epitheca is connected with vertical backshell with the inferior valve rear portion, gas outlet 10 sets up at the epitheca front end, and air inlet 9 sets up anterior at the inferior valve, and the mesochite front end is provided with infrared mark target start button 3, is provided with gas generating device's amount of wind control knob 5 and control button 12 that the control supplied liquid dosing system liquid feed rate on the epitheca, and the inferior valve rear end is provided with power master switch 21, and the mesochite front end is provided with and supplies liquid dosing system start button 4.

The invention can adjust the relevant parameters of the nano spinning by a knob and a button to achieve accurate directional administration.

The air volume control knob 5 can adjust the air output volume of the air pump 24 (the model number of the air pump is VN-T412V 3.2.2L/min 12W) to control the flow velocity and flow volume of the air flow sprayed at the air output volume of the handheld spray gun, so that the auxiliary air flow is adjusted according to actual needs, and the directional deposition of the electro-spun fibers is better realized.

The advancing speed of a push rod of a linear driving motor is controlled by a control button 12 for controlling the liquid supply speed of a liquid supply and drug delivery system, so that the movement speed of a piston of the injector 15 can be accurately controlled, and the speed of the spinning precursor medicament injected into the capillary metal tube by a needle cylinder of the injector 15 is further accurately controlled.

The liquid supply system composed of the syringe 15 needle cylinder, the syringe 15 piston and the miniature linear driving motor is very small and exquisite, the handheld operation is convenient, the propelling speed of the push rod of the linear driving motor is controlled through the motor controller, the power running speed of the syringe 15 piston can be accurately controlled, the liquid supply speed of the spinning precursor medicament liquid of the metal capillary injected into the syringe 15 needle cylinder is further accurately controlled, and the adjustment and the use are convenient.

The shell is provided with a patient connector 29, and the patient connector 29 is connected with the high-voltage power supply generating device 17.

A charging port 22 for charging the high-voltage power supply generation device 17 is provided on the housing.

When the device is in the charging process, the side of the gun body displays that the red light is on, and when the electric quantity is full, the side of the gun body displays that the green light is on. When the charging base consumes about 10% of the electric quantity after being used for a period of time, the blue lamp 7 beside the gun body shell is lighted to prompt that the device should be charged.

The infrared target 11 and the electric quantity alarm part comprise an LM3914 chip U1, a pin 5 of U1 is connected with an adjusting end of a rheostat RV1, one end of the RV1 is respectively connected with one end of a resistor R3, one end of a resistor R2, a pin 8 of U1, a pin 2 of U1, a first end of a switch SW1 and a first end of a switch SW2, the other end of the R2 is respectively connected with pins 6 and 7 of U2, the other end of the R2 is connected with a pin 4 of the U2, and the other end of the RV2 is respectively connected with a pin 3 of the U2, an anode of a diode D2, an anode of the diode D2, a second end of the SW2, a pin 9 of the;

the cathode of the diode D1, the cathode of the diode D2, the cathode of the diode D3, the cathode of the diode D4, the cathode of the diode D5, the cathode of the diode D6, the cathode of the diode D7, the cathode of the diode D8, the cathode of the diode D9 and the cathode of the diode D10 are correspondingly connected with pins 10-18 and 1 of the U1 respectively;

the third end of the SW1 is connected with the negative electrode of a 12V battery BAT1, and the positive electrode of the BAT1 is connected with the fourth end of the SW 1;

the third terminal of SW2 is connected to the anode of diode D11, the anode of diode D12, the cathode of D11 and the cathode of D12 are connected to the fourth terminal of SW 2.

D1-D10 are used for indicating the electric quantity, and the number of the lamp displays is reduced along with the reduction of the electric quantity.

D11 and D12 are infrared targets, and an opening/closing switch is used for opening and closing the infrared targets.

The high-voltage power supply generating device comprises a 555 chip, wherein 4 pins of the 555 chip are respectively connected with one end of a resistor R4 and 8 pins of the 555 chip, the other end of R4 is respectively connected with a first end of a switch SW1, one end of a resistor R3, a pin 7 of the 555 chip and one end of a primary side of a transformer TR1, the other end of the primary side of a TR1 is respectively connected with a collector of an NPN triode Q2 and a collector of an NPN triode Q1, an emitter of the Q2 is respectively connected with a second end of a SW1, a pin 1 of the 555 chip, one end of a capacitor C2, one end of a resistor R2, one end;

the base of Q2 is connected with the emitter of Q1 and the other end of R2, the base of Q1 is connected with pin 3 of U1 through resistor R1, the other end of R3 is connected with pin 2 of 555 chip, pin 6 of 555 chip and the other end of C2, the third end of SW1 is connected with the positive pole of BAT1, the negative pole of BAT1 is connected with the fourth end of SW 1; the other end of the C1 is connected with the anode of a diode D1, and the cathode of D1 is connected with the other end of the secondary side of the TR 1.

The liquid feeding and drug delivery system and the gas generating device comprise a first NE555 chip and a second NE555 chip, wherein a pin 4 of the first NE555 chip is respectively connected with one end of a resistor R1, a pin 8 of the first NE555 chip, a first end of a switch SW1, one end of a resistor R3, a pin 4 of the second NE555 chip, a pin 8 of the second NE555 chip, a cathode of a diode D6 and one end of a second motor, the other end of the second motor is respectively connected with a D6 anode, an NPN triode Q2 collector, a cathode of a diode D3 and a first end of a switch SW2, a base of the Q2 is connected with a pin 3 of the second NE555 chip through a resistor R4, a pin 6 of the second NE555 chip is respectively connected with a pin 2 of the second NE555 chip, one end of a capacitor C4 and an adjusting end of a rheostat RV2, and the other end of the C4 is respectively connected with a pin 1, a pin of the NPN 2, an emitter, a second end of the second NE 1, a pin of the first NE;

one end of RV2 is connected with the anode of diode D4, the cathode of D4 is connected with the other end of resistor R3, the anode of diode D5 and the 7 pin of the second NE555 chip, the 5 pin of the second NE555 chip is grounded through capacitor C5;

the pin 5 of the first NE555 chip is grounded through a capacitor C2, the base electrode of the Q1 is connected with the pin 3 of the first NE555 chip through a resistor R2, the collector electrode of the Q1 is respectively connected with the anode of the D3 and the second end of the SW2, the third end of the SW2 is respectively connected with the fourth end of the SW2 and one end of the first motor, and the other end of the first motor is respectively connected with the fifth end of the SW2 and the sixth end of the SW 2;

the other end of the C1 is respectively connected with a pin 2 of the first NE555 chip, a pin 6 of the first NE555 chip and an adjusting end of a rheostat RV1, one end of the RV1 is connected with the anode of a diode D1, the other end of the RV1 is connected with the cathode of a diode D2, and the cathode of the D1 is respectively connected with the other end of the R1 and the pin 7 of the D2 anode of the first NE555 chip;

the third terminal of SW1 is connected to the positive electrode of battery B1, and the negative electrode of B1 is connected to the fourth terminal of SW 1.

The second motor is an air pump motor.

The metal spring plate 27 is used for clamping the capillary needle tube at the front end of the injector to enable liquid in the injector to enter the spinneret, the metal spring plate 27 is electrically connected with the metal spinneret, the metal spring plate 27 is connected with the positive electrode of the high-voltage power supply generating device 17 through a lead, and the positive electrode of the high-voltage power supply generating device 17 is electrically transmitted to the spinneret through the metal spring plate 27.

The working process of the invention is explained below with reference to the drawings.

When the device is used, the buckle cover of the liquid supply system is firstly opened, and the prepared electric spinning precursor medicament liquid is added into the liquid supply mechanism of the handheld spray gun. And starting an infrared target button, and adjusting the infrared target 11 until the two points coincide to obtain the ideal spinning distance. The method comprises the steps that a power switch is started after the gas output of a gas generating device is adjusted, a liquid supply driving part 16 operates to drive a piston of an injector 15 to move forwards, gas of a gas inlet 9 is conveyed through a guide pipe connected with a gas outlet 10 under the action of the gas generating device, the gas outlet 10 discharges gas to form directional gas flow, a spinning nozzle 14 is connected with the positive electrode of a voltage output end of a high-voltage power generating device 17, spinning precursor liquid generates jet flow at the jet opening of the spinning nozzle 14 under the action of electric field force, the spinning nozzle 14 extends out of a gun body shell from the gas outlet 10, the jet opening of the spinning nozzle 14 is coincided with the central axis of the gas outlet 10, and the spinning precursor liquid jet flow is directionally deposited at a micro-nano electrode or.

When the device is used, the operation can be realized only by aligning the handheld gun mouth to the affected part and opening the start button 3 of the infrared target 11, the use and the adjustment are convenient, meanwhile, the adjustable output gas structure is designed at the front part of the gun body to provide auxiliary gas flow for the handheld spray gun, the operability of the electric defense drug administration process is improved while the portability is maintained, the quality and the yield of the electric defense nanofiber are improved more obviously, in addition, the infrared target 11 designed by the invention can accurately position the spinning distance, and the accurate drug administration is realized.

After the high-voltage power supply generating device is powered by the power supply, the anode of the voltage output end is connected with the spinning nozzle 14 through a lead, and the cathode of the high-voltage power supply generating device is connected with a patient.

It should be understood that the detailed description of the present invention is only for illustrating the present invention and is not limited by the technical solutions described in the embodiments of the present invention, and those skilled in the art should understand that the present invention can be modified or substituted equally to achieve the same technical effects; as long as the use requirements are met, the method is within the protection scope of the invention.