阅读说明：本技术 一种ct和mr异机三维图像融合的配准方法及系统 (Registration method and system for three-dimensional image fusion of CT (computed tomography) and MR (magnetic resonance) different machines ) 是由 王勇 于 2021-06-08 设计创作，主要内容包括：本发明公开了一种CT和MR异机三维图像融合的系统,包括图像预处理模块,用于采集CT图像和MR图像,并对被对采集的图像进行预处理；图像融合模块,用于将CT图像和MR图像进行图像融合；图像评价模块,用于将融合后的图像进行综合评价。本发明首先通过小波去噪方法进行初步处理CT图像与MR图像,然后通过采用NSCT,即非下采样轮廓波变换技术对CT图像与MR图像进行融合,得到CT图像与MR图像融合后的图像,实现了CT图像与MR图像异机融合,其成本低廉、减轻病人的医疗负担、有着广阔的应用空间,并且配准效果良好,所获得的立体融合图像精确度高。(The invention discloses a CT and MR different-machine three-dimensional image fusion system, which comprises an image preprocessing module, a three-dimensional image fusion module and a three-dimensional image fusion module, wherein the image preprocessing module is used for acquiring a CT image and an MR image and preprocessing the acquired images; the image fusion module is used for carrying out image fusion on the CT image and the MR image; and the image evaluation module is used for comprehensively evaluating the fused images. According to the invention, the CT image and the MR image are firstly preliminarily processed by a wavelet denoising method, then the CT image and the MR image are fused by adopting NSCT (non-subsampled contourlet transform), namely a nonsubsampled contourlet transform technology, so that the image fused with the CT image and the MR image is obtained, the different-machine fusion of the CT image and the MR image is realized, the cost is low, the medical burden of a patient is reduced, the application space is wide, the registration effect is good, and the accuracy of the obtained three-dimensional fusion image is high.)

1. A CT and MR different-machine three-dimensional image fusion system is characterized by comprising an image preprocessing module, a three-dimensional image fusion module and a three-dimensional image fusion module, wherein the image preprocessing module is used for acquiring a CT image and an MR image and preprocessing the acquired images;

the image fusion module is used for carrying out image fusion on the CT image and the MR image;

and the image evaluation module is used for comprehensively evaluating the fused images.

2. The system for fusing three-dimensional images of different CT and MR machines according to claim 1, wherein the image preprocessing module comprises a CT scanning module, an MR scanning module and a preliminary processing module.

3. The system for fusing three-dimensional images of a CT and an MR different machine according to claim 2, wherein the CT scanning module is a CT scanner.

4. The system for fusing three-dimensional images of a CT and a MR different machine according to claim 2, wherein the MR scanning module is a nuclear magnetic resonance apparatus.

5. The system for fusing three-dimensional images of a CT and a MR different machine as claimed in claim 2, wherein the preliminary processing module is used for performing geometric correction and denoising on the collected images.

6. The system for fusing the three-dimensional images of the CT and the MR different machines as claimed in claim 1, wherein the image evaluation module has three values of ABC, A is a value, the overall fusion is good, and detail deviation can not be seen by naked eyes; b is usable, the focus is still fused, and other parts have obvious deviation; c is unusable, poor overall fusion, with significant deviation.

7. A registration method for three-dimensional image fusion of CT and MR different machines is characterized by comprising the following steps:

firstly, scanning an affected part through a CT scanning module and an MR scanning module to obtain a CT image and an MR image;

secondly, performing primary processing of geometric correction and denoising on the CT image and the MR image respectively;

thirdly, respectively carrying out NSCT decomposition on the CT image and the MR image after the primary treatment to obtain a low-pass coefficient A and a band-pass direction coefficient A of the CT image and a low-pass coefficient B and a band-pass direction coefficient B of the MR image;

fourthly, performing low-pass coefficient fusion on the low-pass coefficient A of the CT image and the low-pass coefficient B of the MR image, and simultaneously performing band-pass coefficient fusion on the band-pass direction coefficient A of the CT image and the band-pass direction coefficient B of the MR image;

fifthly, performing NSCT reconstruction on the data subjected to low-pass coefficient fusion and band-pass coefficient fusion, namely fusing a CT image and an MR image which can be obtained through NSCT inverse transformation;

and sixthly, after the fusion image is obtained, improving the subjective evaluation scoring table according to clinical requirements, simultaneously evaluating the fusion image of each patient by an attending physician and an imaging physician, and scoring according to the improved subjective evaluation scoring table, if scoring is diverged, scoring through negotiation.

Technical Field

The invention relates to the technical field of digital medical image engineering, in particular to a registration method and a registration system for three-dimensional image fusion of a CT (computed tomography) and an MR (magnetic resonance) different machine.

Background

Positron emission tomography (PET or PT) can obtain image information of a cell metabolism process in vitro in a non-invasive manner, and thus, is widely applied to early diagnosis and precise radiotherapy. Due to the defects of low spatial resolution and low signal-to-noise ratio, the anatomical positioning of a lesion area displayed by a PT image is not good enough and can only be regarded as functional positioning; computed Tomography (CT) images rigid body (bone, joint, etc.) lesions clearly, but does not visualize soft body (blood vessels, nerves, ligaments, joint capsules, etc.) lesions as compared to Magnetic resonance (MRI or MR). Therefore, the result of the fusion of the CT image and the MR image can accurately determine the located focus of hard tissue bone joint and the like and can also accurately determine the located focus of soft tissue.

In the field of image fusion, two-dimensional fusion is changed into high-dimensional fusion, homologous single-mode fusion is changed into heterologous two-mode fusion, black and white fusion is changed into color fusion, anatomical images are changed into functional images, different-machine fusion algorithms similar to the method are more and more developed at home and abroad, the images are more and more accurate, and the fusion level is higher and more.

The image fusion is divided into two modes of same-machine fusion (the scanning of different-source images simultaneously occurs on the same image device) and different-machine fusion (the scanning of different-source images occurs on different image devices at different time intervals). However, the same-machine integration equipment is very expensive, and is not easy to popularize due to high charge, so that the clinical application is limited. In the prior art, the two-dimensional fusion of the same-machine CT image and the MR image is relatively vivid but lacks of stereoscopic vision effect, and the scanning is simultaneously carried out on the same imaging equipment, so that the cost is very high, and the clinical application is limited. The cost of the different-machine fusion is relatively low, the different-machine fusion has wide application space, but the registration effect is not good, and the accuracy of the obtained three-dimensional fusion image is not high.

Disclosure of Invention

The invention aims to provide a registration method and a registration system for three-dimensional image fusion of a CT (computed tomography) and an MR (magnetic resonance) different machine, so as to solve the problems in the background technology.

In order to achieve the purpose, the invention adopts the following technical scheme:

a CT and MR different-machine three-dimensional image fusion system comprises an image preprocessing module, a three-dimensional image fusion module and a three-dimensional image fusion module, wherein the image preprocessing module is used for acquiring a CT image and an MR image and preprocessing the acquired images;

the image fusion module is used for carrying out image fusion on the CT image and the MR image;

and the image evaluation module is used for comprehensively evaluating the fused images.

As a further improvement scheme of the technical scheme: the image preprocessing module comprises a CT scanning module, an MR scanning module and a preliminary processing module.

As a further improvement scheme of the technical scheme: the CT scanning module is a CT scanner.

As a further improvement scheme of the technical scheme: the MR scanning module is a nuclear magnetic resonance apparatus.

As a further improvement scheme of the technical scheme: the preliminary processing module is used for carrying out geometric correction and denoising on the collected images.

As a further improvement scheme of the technical scheme: the image evaluation module has three values ABC, A is valuable, the whole fusion is good, and the detail deviation cannot be seen by naked eyes; b is usable, the focus is still fused, and other parts have obvious deviation; c is unusable, poor overall fusion, with significant deviation.

A registration method for three-dimensional image fusion of CT and MR different machines comprises the following steps:

firstly, scanning an affected part through a CT scanning module and an MR scanning module to obtain a CT image and an MR image;

secondly, performing primary processing of geometric correction and denoising on the CT image and the MR image respectively;

thirdly, respectively carrying out NSCT decomposition on the CT image and the MR image after the primary treatment to obtain a low-pass coefficient A and a band-pass direction coefficient A of the CT image and a low-pass coefficient B and a band-pass direction coefficient B of the MR image;

fourthly, performing low-pass coefficient fusion on the low-pass coefficient A of the CT image and the low-pass coefficient B of the MR image, and simultaneously performing band-pass coefficient fusion on the band-pass direction coefficient A of the CT image and the band-pass direction coefficient B of the MR image;

fifthly, performing NSCT reconstruction on the data subjected to low-pass coefficient fusion and band-pass coefficient fusion, namely fusing a CT image and an MR image which can be obtained through NSCT inverse transformation;

and sixthly, after the fusion image is obtained, improving the subjective evaluation scoring table according to clinical requirements, simultaneously evaluating the fusion image of each patient by an attending physician and an imaging physician, and scoring according to the improved subjective evaluation scoring table, if scoring is diverged, scoring through negotiation.

Compared with the prior art, the invention has the beneficial effects that:

according to the invention, the CT image and the MR image are firstly preliminarily processed by a wavelet denoising method, then the CT image and the MR image are fused by adopting NSCT (non-subsampled contourlet transform), namely a nonsubsampled contourlet transform technology, so that the image fused with the CT image and the MR image is obtained, the different-machine fusion of the CT image and the MR image is realized, the cost is low, the medical burden of a patient is reduced, the application space is wide, the registration effect is good, and the accuracy of the obtained three-dimensional fusion image is high.

The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings. The detailed description of the present invention is given in detail by the following examples and the accompanying drawings.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the invention without limiting the invention. In the drawings:

FIG. 1 is a schematic structural diagram of a registration method for three-dimensional image fusion of CT and MR different machines according to the present invention;

FIG. 2 is a schematic structural diagram of a CT and MR three-dimensional image fusion system according to the present invention;

FIG. 3 is a subjective evaluation scoring table of an image evaluation module in the CT and MR different-machine three-dimensional image fusion registration method and system provided by the invention.

Detailed Description

The principles and features of this invention are described below in conjunction with the following drawings, which are set forth by way of illustration only and are not intended to limit the scope of the invention. The invention is described in more detail in the following paragraphs by way of example with reference to the accompanying drawings. Advantages and features of the present invention will become apparent from the following description and from the claims. It is to be noted that the drawings are in a very simplified form and are not to precise scale, which is merely for the purpose of facilitating and distinctly claiming the embodiments of the present invention.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When a component is referred to as being "connected" to another component, it can be directly connected to the other component or intervening components may also be present. When a component is referred to as being "disposed on" another component, it can be directly on the other component or intervening components may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

Referring to fig. 1 to 3, in an embodiment of the present invention, a system for three-dimensional image fusion of a CT and MR different machine includes an image preprocessing module, configured to acquire a CT image and an MR image and preprocess the acquired images;

the image fusion module is used for carrying out image fusion on the CT image and the MR image;

and the image evaluation module is used for comprehensively evaluating the fused images.

Preferably, the image preprocessing module comprises a CT scanning module, an MR scanning module and a preliminary processing module

Preferably, the CT scanning module is a CT scanner, and the CT scanner scans the lesion of the patient to obtain a CT image.

Preferably, the MR scanning module is an nmr scanner, and the MR image is obtained by scanning the lesion of the patient with the nmr scanner.

Preferably, the preliminary processing module performs geometric correction and denoising on the collected image, performs preliminary processing on the image by using a wavelet denoising method, performs wavelet decomposition on the image signal at first, performs threshold quantization on the high-frequency coefficient subjected to hierarchical decomposition, and reconstructs the image signal by using a two-dimensional wavelet, thereby preliminarily completing image processing.

Preferably, the image evaluation module has three values of ABC, A is valuable, the whole fusion is good, and the detail deviation cannot be seen by naked eyes; b is usable, the focus is still fused, and other parts have obvious deviation; c is unusable, poor overall fusion, with significant deviation.

Preferably, the registration method for three-dimensional image fusion of the CT and MR different machines comprises the following steps:

firstly, scanning an affected part through a CT scanning module and an MR scanning module to obtain a CT image and an MR image;

secondly, performing primary processing of geometric correction and denoising on the CT image and the MR image respectively;

thirdly, respectively carrying out NSCT decomposition on the CT image and the MR image after the primary treatment to obtain a low-pass coefficient A and a band-pass direction coefficient A of the CT image and a low-pass coefficient B and a band-pass direction coefficient B of the MR image;

fourthly, performing low-pass coefficient fusion on the low-pass coefficient A of the CT image and the low-pass coefficient B of the MR image, and simultaneously performing band-pass coefficient fusion on the band-pass direction coefficient A of the CT image and the band-pass direction coefficient B of the MR image;

fifthly, performing NSCT reconstruction on the data subjected to low-pass coefficient fusion and band-pass coefficient fusion, namely fusing a CT image and an MR image which can be obtained through NSCT inverse transformation;

and sixthly, after the fusion image is obtained, improving the subjective evaluation scoring table according to clinical requirements, simultaneously evaluating the fusion image of each patient by an attending physician and an imaging physician, and scoring according to the improved subjective evaluation scoring table, if scoring is diverged, scoring through negotiation.

Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and/or modifications of the invention can be made, and equivalents and modifications of some features of the invention can be made without departing from the spirit and scope of the invention.