阅读说明：本技术 一种适用于食欲不振的助消化粉 (Digestion-aiding powder suitable for loss of appetite ) 是由 岳玉荣 于 2021-07-30 设计创作，主要内容包括：本发明属于中药技术领域,具体涉及一种适用于食欲不振的助消化粉。所述助消化粉制备原料包括以下组分,乌梅、白芍、苦瓜、焦山楂、苍术、南瓜花、龙胆、茵陈、厚朴、枸杞子、红枣、枳壳、雪莲、木香、金银花、金钱草、香附、苦参、维生素A、维生素B-(1)、维生素B-(2)、维生素B-(6)、维生素B-(12)、维生素C和叶酸。本发明采用多种中药和药食同源的原料得到了一种适用于孕期食欲不振的,效果较好的助消化粉,其中苍术、厚朴、木香、枸杞和枳壳合理搭配起到很好地胃排空作用,减少患者胃胀、积滞等症状,而进一步复配本发明其他组分,更能提高患者的食物利用率,起到助消化的作用。(The invention belongs to the technical field of traditional Chinese medicine, and provides a Chinese medicinal preparationRelates to a digestion-aiding powder suitable for inappetence. The raw materials for preparing the digestion-aiding powder comprise dark plum, white paeony root, bitter gourd, scorched hawthorn fruit, rhizoma atractylodis, cushaw flower, gentian, oriental wormwood, officinal magnolia bark, barbary wolfberry fruit, red date, bitter orange, snow lotus, costustoot, honeysuckle flower, longhairy antenoron herb, nutgrass galingale rhizome, lightyellow sophora root, vitamin A and vitamin B 1 Vitamin B 2 Vitamin B 6 Vitamin B 12 Vitamin C and folic acid. The digestion-aiding powder suitable for anorexia during pregnancy and good in effect is obtained by adopting various traditional Chinese medicines and raw materials which are homologous in medicine and food, wherein the rhizoma atractylodis, the mangnolia officinalis, the elecampane, the fructus lycii and the fructus aurantii are reasonably matched to play a good role in emptying the stomach, so that symptoms such as gastrectasia, indigestion and the like of a patient are reduced, and the other components are further compounded, so that the food utilization rate of the patient can be improved, and the digestion-aiding effect is achieved.)

1. A digestion-aiding powder suitable for loss of appetite is prepared from the following raw materials in parts by weight,

5-9 parts of dark plum fruit, 2-6 parts of white peony root, 5-8 parts of bitter gourd, 12-25 parts of scorched hawthorn fruit, 5-9 parts of rhizoma atractylodis, 6-10 parts of pumpkin flower, 2-7 parts of gentian, 5-8 parts of oriental wormwood, 3-15 parts of magnolia officinalis, 5-20 parts of wolfberry fruit, 5-20 parts of red date, 5-7 parts of bitter orange, 5-10 parts of snow lotus, 5-25 parts of costustoot, 10-20 parts of honeysuckle, 5-10 parts of desmodium, 5-10 parts of rhizoma cyperi, 5-10 parts of radix sophorae flavescentis, 0.0002-0.0006 part of vitamin A, and 5-25 parts of vitamin B₁ 0.002～0.006 parts, vitamin B₂0.002-0.006 part of vitamin B₆0.002-0.006 part of vitamin B₁₂0.0002 to 0.0006 portion of vitamin C, 0.2 to 0.6 portion of vitamin C and 0.01 to 0.1 portion of folic acid.

2. The digestion powder as claimed in claim 1, wherein the preparation raw material comprises the following components by weight portion,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 18 parts of scorched hawthorn fruit, 7 parts of rhizoma atractylodis, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costus root, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A and 7 parts of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

3. A method for preparing the digestion-aiding powder as claimed in any one of claims 1 or 2, wherein the raw materials are mixed according to parts by weight and ground into powder.

4. A method of preparing a digestion powder as claimed in any one of claims 1 or 2, comprising the steps of:

s1: mixing mume fructus, radix Paeoniae alba, fructus Momordicae Charantiae, fructus crataegi preparata, rhizoma Atractylodis, flos Cucurbitae, radix Gentianae, herba Artemisiae Scopariae, cortex Magnolia officinalis and fructus Lycii, grinding into powder, extracting with ethanol, filtering, and drying to obtain extract A;

s2: mixing fructus Jujubae, fructus Aurantii, herba Saussureae Involueratae, radix aucklandiae, flos Lonicerae, herba Lysimachiae Christinae, rhizoma Cyperi and radix Sophorae Flavescentis, grinding into powder, extracting with water-acetone, filtering and drying to obtain extract B;

s3: mixing extract A, extract B, vitamin A, and vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂Mixing the vitamin C and the folic acid, and grinding the mixture into powder to obtain the digestion-aiding powder.

5. The method as claimed in claim 4, wherein the milling step S1 is carried out by milling the mixture into 100-150 mesh powder.

6. The method of claim 4, wherein the ethanol extraction in S1 is performed at 60-80 ℃ for 20-24 hours at 15-20 times the total weight of the S1 raw material.

7. The method as claimed in claim 4, wherein the milling step S2 is carried out by milling the mixture into 100-150 mesh powder.

8. The preparation method of claim 4, wherein the water-acetone extraction is performed at a water-acetone volume ratio of (3-5):1, a total amount of water-acetone used 10-20 times of the total weight of the S2 raw material, and a temperature of 40-60 ℃ for 10-12 hours.

9. The method as claimed in claim 4, wherein in the step S3, the step of grinding is carried out by grinding the mixture into 150-mesh powder of 100 meshes.

10. Use of a digestive powder according to any one of claims 1 to 2 or a method according to any one of claims 3 to 9 in the preparation of a product associated with digestion.

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to digestion-aiding powder suitable for inappetence.

Background

Functional Dyspepsia (FD) belongs to digestive system diseases and can be classified into subgroups of dyskinetic dyspepsia, ulcerative dyspepsia, and nonspecific dyspepsia. The main symptoms are various digestive tract symptoms such as nausea, distention after eating for a long time, persistent abdominal distension, belching, epigastric pain, abnormal defecation and the like, but the auxiliary examination of the internal medicine has no obvious organic lesions. In FD diseases, the secretion of digestive enzymes, the absorption of food, the functions of a secretion system, a digestive tract power system, immunity, psychology and the like in an organism are abnormal, the pathological mechanism is complex, symptoms can occur repeatedly, the life quality of a patient is seriously reduced, and the mood of the patient is influenced.

At present, no specific therapy aiming at functional dyspepsia is available, experience treatment is mainly used, and different treatment schemes such as gastric acid secretion inhibition, gastrointestinal motility promoting drugs, helicobacter pylori eradication, antidepressant drugs and other gastric mucosa protective agents are performed according to the condition of a patient.

Pregnant people have a series of reactions such as dizziness, hypodynamia, inappetence, preference for acid food, aversion to greasy food, nausea, morning vomiting and the like due to the fact that chorionic gonadotropin (HCG) is increased, gastric acid secretion is reduced and gastric emptying time is prolonged, and the reactions are collectively called pregnancy reactions. Symptoms are similar to functional dyspepsia symptoms, but the market for products that alleviate pregnancy reactions is rare.

Chinese patent application CN105212205A discloses a composition for relieving vomiting of pregnant women and a preparation method thereof, wherein the preparation method of the composition comprises the following steps: (1) decocting: 5-9 parts of decocted honey-fried licorice root, 8-12 parts of dried orange peel and 4-6 parts of shaddock peel for 10-20 minutes, and 15-25 parts of concentrated solution is extracted after cooling for later use; (2) juicing: respectively juicing 20-50 parts of ginger, 30-50 parts of carrot, 1-5 parts of dragon fruit and 10-12 parts of dark plum, mixing with 10-15 parts of perilla leaf extract and 25-30 parts of fructus amomi extract, and filtering through fine cotton cloth for later use; (3) and (5) preparing a product.

Chinese patent application CN104815275A discloses an oral medicine for treating pregnancy reaction and a preparation method thereof, wherein the medicine comprises the following components in parts by mass: radix pseudostellariae, polygala tenuifolia, fructus amomi, spina date seed, semen cuscutae, radix ophiopogonis, fried eucommia ulmoides, dark plum pulp, cornus officinalis and ginger bamboo shavings 1-3 parts respectively. The preparation method of the medicine comprises the following steps: A. selecting high-quality clean first-grade radix pseudostellariae, polygala tenuifolia, fructus amomi, spina date seed, semen cuscutae, radix ophiopogonis, fried eucommia ulmoides, dark plum pulp, cornus officinalis and ginger bamboo shavings according to the mass part ratio, and respectively removing residual impurities and dust for later use; B. soaking the raw materials in cold boiled water for about half an hour until the materials penetrate into the tissues of the medicines, then placing the soaked medicines into an earthen pot, adding cold boiled water which is 45mm above the medicines, boiling with strong fire, decocting with slow fire for 35 minutes, pouring out the liquid medicine, adding warm boiled water again, decocting for 30 minutes, mixing twice, and filtering to obtain 600 ml of the liquid medicine.

Disclosure of Invention

The invention aims to provide digestion-aiding powder suitable for inappetence during pregnancy aiming at the problems of less products and poor effect in the prior art.

The purpose of the invention is realized by the following technical scheme.

A digestion-aiding powder suitable for anorexia during pregnancy is prepared from the following raw materials in parts by weight,

5-9 parts of dark plum fruit, 2-6 parts of white peony root, 5-8 parts of bitter gourd, 12-25 parts of scorched hawthorn fruit, 5-9 parts of rhizoma atractylodis, 6-10 parts of pumpkin flower, 2-7 parts of gentian, 5-8 parts of oriental wormwood, 3-15 parts of magnolia officinalis, 5-20 parts of wolfberry fruit, 5-20 parts of red date, 5-7 parts of bitter orange, 5-10 parts of snow lotus, 5-25 parts of costustoot, 10-20 parts of honeysuckle, 5-10 parts of desmodium, 5-10 parts of rhizoma cyperi, 5-10 parts of radix sophorae flavescentis, 0.0002-0.0006 part of vitamin A, and 5-25 parts of vitamin B₁0.002-0.006 part of vitamin B₂0.002-0.006 part of vitamin B₆0.002-0.006 part of vitamin B₁₂0.0002 to 0.0006 portion of vitamin C, 0.2 to 0.6 portion of vitamin C and 0.01 to 0.1 portion of folic acid.

Furthermore, the digestion-aiding powder is prepared from the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 18 parts of scorched hawthorn fruit, 7 parts of rhizoma atractylodis, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costus root, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A and 7 parts of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

The preparation method of the digestion-aiding powder can be obtained by directly mixing and grinding the raw materials in parts.

A preparation method of the digestion-aiding powder comprises the steps of mixing the raw materials in parts by weight, and grinding the mixture into powder.

Further, the grinding is to grind the powder material with 100-150 meshes.

The digestion powder can also be obtained by extracting the raw materials in parts by weight by a proper extraction method.

A preparation method of the digestion-aiding powder comprises the following steps:

s1: mixing mume fructus, radix Paeoniae alba, fructus Momordicae Charantiae, fructus crataegi preparata, rhizoma Atractylodis, flos Cucurbitae, radix Gentianae, herba Artemisiae Scopariae, cortex Magnolia officinalis and fructus Lycii, grinding into powder, extracting with ethanol, filtering, and drying to obtain extract A;

s2: mixing fructus Jujubae, fructus Aurantii, herba Saussureae Involueratae, radix aucklandiae, flos Lonicerae, herba Lysimachiae Christinae, rhizoma Cyperi and radix Sophorae Flavescentis, grinding into powder, extracting with water-acetone, filtering and drying to obtain extract B;

s3: mixing extract A, extract B, vitamin A, and vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂Mixing the vitamin C and the folic acid, and grinding the mixture into powder to obtain the digestion-aiding powder.

Further, in S1, the milling is to mill the mixture into 100-150 mesh powder.

Further, in S1, the ethanol extraction is carried out at 60-80 ℃ for 20-24 hours, wherein the dosage of the ethanol is 15-20 times of the total weight of the S1 raw materials.

Further, in S2, the milling is to mill the mixture into 100-150 mesh powder.

Further, the water-acetone extraction is carried out for 10-12 hours at the temperature of 40-60 ℃ when the volume ratio of water to acetone is (3-5):1, the total using amount of the water-acetone is 10-20 times of the total weight of the S2 raw material.

Further, in the step S3, the milling is to mill the mixture into 100-150 mesh powder.

The invention has the advantages that:

1. the digestion-aiding powder suitable for anorexia during pregnancy and good in effect is obtained by adopting various traditional Chinese medicines and raw materials which are homologous in medicine and food, wherein the rhizoma atractylodis, the mangnolia officinalis, the elecampane, the fructus lycii and the fructus aurantii are reasonably matched to play a good role in emptying the stomach, so that symptoms such as gastrectasia, indigestion and the like of a patient are reduced, and the other components are further compounded, so that the food utilization rate of the patient can be improved, and the digestion-aiding effect is achieved.

2. The bitter gourd, the radix sophorae flavescentis, the white paeony root, the gentian, the mangnolia officinalis, the rhizoma atractylodis, the fructus aurantii and other components in the components have a better taste and are not easy to enter the mouth, and the dark plum, the scorched hawthorn fruit, the red date, the snow lotus, the honeysuckle and other components are matched to cover pungent smell through fruit fragrance and flower fragrance, so that a user has better compliance and higher acceptability.

3. The digestion-aiding powder can be directly ground into powder to obtain a finished product, and can also obtain a better treatment effect by a proper extraction method.

Detailed Description

The raw materials used in the examples of the present invention are all commercially available dry products with a moisture content of 5-10%.

Example 1

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

9 parts of dark plum fruit, 2 parts of white paeony root, 8 parts of balsam pear, 12 parts of scorched hawthorn fruit, 9 parts of rhizoma atractylodis, 6 parts of cushaw flower, 7 parts of gentian, 5 parts of oriental wormwood and magnolia officinalis3 parts of medlar 20 parts, red date 5 parts, bitter orange 6 parts, snow lotus 10 parts, costustoot 5 parts, honeysuckle 20 parts, longhairy antenoron herb 10 parts, nutgrass galingale rhizome 10 parts, lightyellow sophora root 10 parts, vitamin A0.0006 part and vitamin B₁0.002 part of vitamin B₂0.006 part of vitamin B₆0.006 part of vitamin B₁₂0.0002 part, 0.2 part of vitamin C and 0.01 part of folic acid.

Drying the raw materials of the components, mixing, and grinding the raw materials together to obtain powder of 100 meshes, thereby obtaining the digestion-aiding powder.

Example 2

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

5 parts of dark plum fruit, 6 parts of white paeony root, 5 parts of balsam pear, 25 parts of scorched hawthorn fruit, 5 parts of rhizoma atractylodis, 10 parts of pumpkin flower, 2 parts of gentian, 5 parts of oriental wormwood, 15 parts of officinal magnolia bark, 5 parts of barbary wolfberry fruit, 20 parts of red date, 6 parts of bitter orange, 5 parts of snow lotus, 25 parts of costustoot, 10 parts of honeysuckle flower, 5 parts of longhairy antenoron herb, 5 parts of nutgrass galingale rhizome, 5 parts of lightyellow sophora root, 0.0002 part of vitamin A and 0.0002 part of vitamin B₁0.006 part of vitamin B₂0.002 part of vitamin B₆0.002 part of vitamin B₁₂0.0006 part, 0.6 part of vitamin C and 0.1 part of folic acid.

Drying the raw materials of the components, mixing, and grinding the raw materials together to 150-mesh powder to obtain the digestion-aiding powder.

Example 3

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 18 parts of scorched hawthorn fruit, 7 parts of rhizoma atractylodis, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costus root, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A and 7 parts of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

Drying the raw materials of the components, mixing, and grinding the raw materials together to 150-mesh powder to obtain the digestion-aiding powder.

Example 4

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 18 parts of scorched hawthorn fruit, 7 parts of rhizoma atractylodis, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costus root, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A and 7 parts of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

The digestion-aiding powder is prepared by the following steps:

a preparation method of the digestion-aiding powder comprises the following steps:

s1: mixing and grinding dark plum, white paeony root, bitter gourd, scorched hawthorn fruit, rhizoma atractylodis, cushaw flower, gentian, oriental wormwood, mangnolia officinalis and medlar to 100-mesh powder, adding ethanol with the weight part being 20 times of the total parts of the raw materials in the step, heating to 60 ℃, extracting for 20 hours, filtering while hot, recovering filtrate, concentrating and drying to obtain an extract A;

s2: mixing and grinding red date, fructus aurantii, saussurea involucrate, elecampane, honeysuckle, desmodium, rhizoma cyperi and radix sophorae flavescentis to 150-mesh powder, adding water-acetone mixed liquor which is 20 times of the total parts by weight of the raw materials in the step, wherein the volume ratio of the water to the acetone is 3:1, heating to 40 ℃, extracting for 12 hours, filtering while hot, recovering the filtrate, concentrating and drying to obtain an extract B;

s3: mixing extract A, extract B, vitamin A, and vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂Mixing the vitamin C and the folic acid, and grinding the mixture to 150 meshes of powder to obtain the digestion-aiding powder, wherein the total amount is 36 parts.

Example 5

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white peony root, 7 parts of balsam pear,18 parts of scorched hawthorn fruit, 7 parts of swordlike atractylodes rhizome, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costustoot, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A, and 0.0004 part of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

The digestion-aiding powder is prepared by the following steps:

a preparation method of the digestion-aiding powder comprises the following steps:

s1: mixing and grinding dark plum, white paeony root, bitter gourd, scorched hawthorn fruit, rhizoma atractylodis, cushaw flower, gentian, oriental wormwood, mangnolia officinalis and medlar to 150-mesh powder, adding ethanol with the weight part 15 times of the total parts of the raw materials, heating to 80 ℃, extracting for 24 hours, filtering while hot, recovering filtrate, concentrating and drying to obtain an extract A;

s2: mixing and grinding red date, fructus aurantii, saussurea involucrate, elecampane, honeysuckle, desmodium, rhizoma cyperi and radix sophorae flavescentis to 100-mesh powder, adding water-acetone mixed liquor which is 10 times of the total parts of the raw materials in the step in parts by weight, wherein the volume ratio of the water to the acetone is 5:1, heating to 60 ℃, extracting for 10 hours, filtering while hot, recovering the filtrate, concentrating, and drying to obtain an extract B;

s3: mixing extract A, extract B, vitamin A, and vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂Mixing the vitamin C and the folic acid, and grinding the mixture to 150 meshes of powder to obtain the digestion-aiding powder, wherein the total amount is 40 parts.

Comparative example 1

The difference from the example 3 is that the parts of the scorched hawthorn fruit, the atractylodes rhizome, the officinal magnolia bark and the costus root are different

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 5 parts of scorched hawthorn fruit, 22 parts of rhizoma atractylodis, 8 parts of cushaw flower, 5 parts of gentian, 7 parts of oriental wormwood, 20 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, and 3 parts of costustoot15 parts of honeysuckle, 7 parts of desmodium, 8 parts of rhizoma cyperi, 8 parts of radix sophorae flavescentis, 0.0004 part of vitamin A and vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

Drying the raw materials of the components, mixing, and grinding the raw materials together to 150-mesh powder to obtain the digestion-aiding powder.

Comparative example 2

The difference from example 4 is that all feedstocks were extracted using ethanol

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 18 parts of scorched hawthorn fruit, 7 parts of rhizoma atractylodis, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costus root, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A and 7 parts of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

The digestion-aiding powder is prepared by the following steps:

a preparation method of the digestion-aiding powder comprises the following steps:

s1: mixing the raw materials except the vitamins and the folic acid, grinding the raw materials into 100-mesh powder, adding 20 times of ethanol by weight of the total parts of the raw materials in the step, heating to 60 ℃, extracting for 20 hours, filtering while hot, recovering the filtrate, concentrating and drying to obtain an extract A;

s2: mixing extract A, vitamin A, and vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂Mixing the vitamin C and the folic acid, and grinding the mixture to 150-mesh powder to obtain 51 parts of the digestion-aiding powder.

Comparative example 3

The difference from example 4 is that pure acetone extraction was used in S2

A digestion-aiding powder suitable for anorexia during pregnancy comprises the following raw materials in parts by weight,

7 parts of dark plum fruit, 4 parts of white paeony root, 7 parts of balsam pear, 18 parts of scorched hawthorn fruit, 7 parts of rhizoma atractylodis, 8 parts of pumpkin flower, 5 parts of gentian, 7 parts of oriental wormwood, 10 parts of officinal magnolia bark, 12 parts of barbary wolfberry fruit, 15 parts of red date, 6 parts of bitter orange, 8 parts of snow lotus, 15 parts of costus root, 15 parts of honeysuckle flower, 7 parts of longhairy antenoron herb, 8 parts of nutgrass galingale rhizome, 8 parts of lightyellow sophora root, 0.0004 part of vitamin A and 7 parts of vitamin B₁0.004 portion of vitamin B₂0.004 portion of vitamin B₆0.004 portion of vitamin B₁₂0.0004 part, 0.4 part of vitamin C and 0.05 part of folic acid.

The digestion-aiding powder is prepared by the following steps:

a preparation method of the digestion-aiding powder comprises the following steps:

s1: mixing and grinding dark plum, white paeony root, bitter gourd, scorched hawthorn fruit, rhizoma atractylodis, cushaw flower, gentian, oriental wormwood, mangnolia officinalis and medlar to 100-mesh powder, adding ethanol with the weight part being 20 times of the total parts of the raw materials in the step, heating to 60 ℃, extracting for 20 hours, filtering while hot, recovering filtrate, concentrating and drying to obtain an extract A;

s2: mixing and grinding red date, fructus aurantii, saussurea involucrate, elecampane, honeysuckle, desmodium, rhizoma cyperi and radix sophorae flavescentis to 150-mesh powder, adding 20 weight parts of acetone in the total parts of the raw materials in the step, heating to 40 ℃, extracting for 12 hours, filtering while hot, recovering filtrate, concentrating and drying to obtain an extract B;

s3: mixing extract A, extract B, vitamin A, and vitamin B₁Vitamin B₂Vitamin B₆Vitamin B₁₂Mixing the vitamin C and the folic acid, and grinding the mixture to 150 meshes of powder to obtain the digestion-aiding powder, wherein the total amount is 33 parts.

The invention verifies the digestion-aiding effect of the product from two aspects of the gastric emptying experiment and the digestive enzyme activity of the rat.

Gastric emptying experiment

Experimental animals: SPF grade SD rats, female, 180-. During the experiment, the rats are raised in a quiet environment and are raised in cages, and are fed with common feed (which accords with GB 14924.3-2001 experimental animal mouse and rat compound feed) and freely eat drinking water. The drinking water and the feed are changed every day, so that the ventilation, cleanness and sanitation of the living environment of the animals are kept. Day (12 +/-2) hours, indoor temperature (20 +/-2) DEG C and relative humidity of 40-60 percent. Rats were housed for one week at baseline and were randomized into groups.

Modeling functional dyspepsia: the rat was held at the distal end 1/3 of the tail of the rat with a sponge of long sea, and the rat was subjected to violent and aggressive tearing with other rats to irritate the whole cage rat for 0.5 h/time. With the aggravation of fighting, rats can be scratched, in order to avoid inflammation interference, the injured parts are smeared with 0.5% iodophor to prevent infection, stimulation is carried out for 1 time and 4 times per day every 3 hours, the food intake is reduced after continuous stimulation is carried out for 7 days and 7 days, the gastric emptying rate is reduced, and the success of model building can be judged.

And (3) determination of digestive enzyme activity: the digestive enzyme activity of each experimental rat is tested after the model is made and the experimental period is over, and the test method refers to the experimental method for the digestive enzyme activity determination in the technical Specification for health food inspection and evaluation (2003 edition).

Calculating the gastric emptying rate: the rats are forbidden to eat water for 24h, then the rats are filled with 1g/mL of semisolid nutrient paste at a ratio of 10mL/kg, after standing for 1h, the rats are killed by cutting off the head, the abdominal cavity is cut open, the cardia and the pylorus are tied by using threads, the esophagus and the duodenum are cut off by clinging to the tying threads, and the stomachs are taken out. The stomach mass is weighed and recorded by using the balance; then cutting the stomach wall, washing the stomach contents with distilled water, sucking the water with filter paper, weighing the mass of the empty stomach, and finally calculating the gastric emptying rate: the gastric emptying rate is [ gavage amount- (stomach mass-stomach net mass) ]/gavage amount x 100%.

The formula of the semi-solid nutrient paste comprises: 10g of sodium carboxymethylcellulose (CMC-Na) is dissolved in 200mL of distilled water, 16g of milk powder, 8g of sugar, 8g of starch, 4mL of carbon ink and distilled water are respectively added, the mixture is uniformly stirred once, 300mL of black semisolid paste is prepared, the mixture is refrigerated in a refrigerator, and the black semisolid paste is taken out 2h before use and is returned to the room temperature.

The administration time is as follows: and (3) administration is started the next day after the molding is finished, the intragastric administration is carried out once every day at a fixed time, the intragastric distilled water with the same volume is infused in an experimental group without administration, and the administration period is 10 days.

Grouping and administration dose:

the normal control group is not subjected to molding treatment, and is fed with normal diet without medicine;

after model building, eating normally without dosing;

example 3, example 4, comparative examples 1-3, the dosage was calculated based on crude drug amount, and the dosage was 500mg/kg based on crude drug amount^.BW；

The number of rats in each experimental group was 5.

The results are shown in Table 1.

Table 1 data of experimental results of each group

Compared with a normal control group: p < 0.05, P < 0.01

The digestive powder can well recover the pepsin activity and the gastric emptying capacity of rats with functional dyspepsia, and can be used for well helping digestion in improving functional dyspepsia.

Finally, it should be noted that the above-mentioned contents are only used for illustrating the technical solutions of the present invention, and not for limiting the protection scope of the present invention, and that the simple modifications or equivalent substitutions of the technical solutions of the present invention by those of ordinary skill in the art can be made without departing from the spirit and scope of the technical solutions of the present invention.