阅读说明：本技术 一种自动制冷恒温冰袋及其制备工艺 (Automatic refrigeration constant-temperature ice bag and preparation process thereof ) 是由 丁文凯 于 2019-09-25 设计创作，主要内容包括：本发明公开了一种自动制冷恒温冰袋及其制备工艺。自动制冷恒温冰袋,包括外袋,所述外袋内设置有内袋、制冷剂和蓄冷剂,所述内袋密闭装有水。本发明的自动制冷恒温冰袋通过在外袋中设置内袋、制冷剂和蓄冷剂,将内袋捏破后,内袋中的水流出来与制冷剂充分接触,可以使温度快速降低,降温后,蓄冷剂进一步溶于低温的溶液中,进而形成凝胶,起到控温的作用,使外袋内的温度长时间保持在低温状态；且本发明的自动制冷恒温冰袋体积小、重量轻、可随身携带,使用方便,随用随取,可根据医用生物制品数量和容积,配备不同数量的冰袋。自动制冷恒温冰袋制备工艺,包括：将水装于内袋中,封口；将内袋、制冷剂、蓄冷剂装于外袋中,封口。(The invention discloses an automatic refrigeration constant-temperature ice bag and a preparation process thereof. The automatic refrigeration constant temperature ice bag comprises an outer bag, wherein an inner bag, a refrigerant and a coolant are arranged in the outer bag, and the inner bag is hermetically filled with water. According to the automatic refrigeration constant-temperature ice bag, the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant temperature ice bag has small volume, light weight, portability, convenient use and random access, and can be provided with different numbers of ice bags according to the number and the volume of medical biological products. The preparation process of the automatic refrigeration constant temperature ice bag comprises the following steps: filling water into the inner bag, and sealing; the inner bag, the refrigerant and the cold storage agent are filled in the outer bag and sealed.)

1. An automatic refrigeration constant temperature ice bag which characterized in that: the cold storage bag comprises an outer bag, wherein an inner bag, a refrigerant and a cold storage agent are arranged in the outer bag, and water is hermetically filled in the inner bag.

2. An automatic refrigerating thermostatic ice bag as claimed in claim 1, wherein: the refrigerant is carbamide.

3. An automatic refrigerating thermostatic ice bag as claimed in claim 2, wherein: the cold storage agent is sodium polyacrylate.

4. An automatic refrigerating thermostatic ice bag as claimed in claim 3, wherein: the refrigerant, the water and the coolant are respectively 105 parts, 100 parts and 5 parts by mass.

5. An automatic refrigerating thermostatic ice bag as claimed in claim 1, wherein: the outer bag is a closed composite film bag.

6. An automatic refrigerating thermostatic ice bag as claimed in claim 1, wherein: the inner bag is a sealed plastic bag.

7. An automatic refrigerating thermostatic ice bag as claimed in any one of claims 1 to 6 wherein: a non-woven fabric bag is arranged in the outer bag, and the coolant is filled in the non-woven fabric bag.

8. An automatic refrigerating thermostatic ice bag as claimed in claim 7 wherein: the specification of the outer bag is 25 cmX12.5cm;

the specification of the inner bag is 12cmX8 cm;

the specification of the non-woven cloth bag is 8cmX6 cm.

9. A preparation process of an automatic refrigeration constant-temperature ice bag is characterized by comprising the following steps:

filling water into the inner bag, and sealing;

the inner bag, the refrigerant and the cold storage agent are filled in the outer bag and sealed.

Technical Field

The invention relates to the technical field of medical biological product cold chain transportation, in particular to an automatic refrigeration constant-temperature ice bag and a preparation process thereof.

Background

The medical cold chain transportation needs to be carried by a refrigerator car, and the temperature is controlled to be 2^-At the temperature of 8 ℃, and can not be transported together with fruits and seafood. The company like the Shufeng cold chain charges 250 Yuan for short-distance transportation within 100 kilometers, and the transportation cost is high.

Some companies with strong strength and large sales quantity configure refrigerated vehicles by themselves and transport medical cold chain goods by themselves. The companies with weak strength and low sales volume cannot arrange the refrigerator cars by themselves or carry the goods such as the smooth and rich cold chain.

The short-distance transportation can adopt foamThe heat preservation box is matched with a proper amount of ice bags, so that the temperature can be kept at 2 DEG^-Transporting the medical biological product at 8 ℃. The traditional ice bag needs to be frozen in a refrigerator for 24 hours and can be used after cold accumulation. The refrigerator is depended on, the power supply is depended on, the time is limited, and the refrigerator cannot be taken and used at any time. For some outdoor and special cases, the refrigerator is not available, the power supply is not available, and the refrigerator is required to be used immediately, which is very inconvenient.

Some companies adopt a normal-temperature transportation mode for vaccines due to various condition limitations of medical cold-chain long-distance transportation and short-distance transportation, so that a toxic vaccine event with great social harm is caused. The vaccine stimulates the human immune system through the antigen part, thereby protecting the human health. The core of the vaccine is antigen, the biological activity of the antigen is not ensured, and most of the vaccines are 2^-Storing and transporting at 8 deg.C. The problems caused by vaccine inactivation are two kinds: 1. vaccine inactivation is not perceived and can have serious consequences for vaccines such as rabies, tetanus and the like, by exposing the vaccinee unconsciously to the corresponding disease. 2. Inactivation of the vaccine, which corresponds to injection of the corresponding pathogen into the vaccinee, leads to the development of new diseases.

Disclosure of Invention

Based on the above, the invention aims to provide an automatic refrigeration constant-temperature ice bag and a preparation process thereof.

The automatic refrigeration constant temperature ice bag comprises an outer bag, wherein an inner bag, a refrigerant and a coolant are arranged in the outer bag, and the inner bag is hermetically filled with water.

According to the automatic refrigeration constant-temperature ice bag, the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant temperature ice bag has small volume, light weight, portability, convenient use and random access, and can be provided with different numbers of ice bags according to the number and the volume of medical biological products.

Further preferably, the refrigerant is carbamide. The carbamide can absorb heat and refrigerate quickly when dissolved in water, so that the temperature is quickly reduced to about 2 ℃, and the carbamide has low price and high safety, and can reduce the production cost and ensure the safety.

Further preferably, the coolant is sodium polyacrylate. The sodium polyacrylate is a high molecular compound with hydrophilic and hydrophobic groups, is slowly dissolved in water to form extremely viscous transparent gel, so that the constant temperature is kept for a long time, the temperature is conveniently controlled to be 2-8 ℃, the cost of the sodium polyacrylate is low, the sodium polyacrylate is safe, and the manufactured ice bag is cheap, high in quality and safe.

Further preferably, the refrigerant, the water, and the coolant are 105 parts, 100 parts, and 5 parts, respectively, by mass. The refrigerant, the water and the coolant are arranged according to the mass parts, so that the refrigeration and constant temperature effects of the ice bag can be ensured while materials are saved and the volume is reduced.

Further preferably, the outer bag is a closed composite film bag. The composite film bag has stable structure and low cost.

Further preferably, the inner bag is a sealed plastic bag. The plastic bag is convenient to break by pinching and has low cost.

Further preferably, a non-woven fabric bag is arranged in the outer bag, and the coolant is filled in the non-woven fabric bag. The non-woven fabric bag can facilitate the solution to permeate, so that the coolant is more fully dissolved in the solution.

Further preferably, the outer bag has a specification of 25 cmX12.5cm;

the specification of the inner bag is 12cmX8 cm;

the specification of the non-woven cloth bag is 8cmX6 cm.

The outer bag, the inner bag and the non-woven bag are designed into the specifications, so that the ice bag has small volume, light weight, portability, convenient use and low production cost.

Compared with the prior art, the automatic refrigeration constant-temperature ice bag has the advantages that the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant-temperature ice bag has small volume, light weight, portability, convenient use and convenient taking at any time, and can be provided with ice bags with different quantities according to the quantity and the volume of reagents. The automatic refrigeration constant temperature ice bag has the characteristics of simple structure, small volume, convenient use and the like.

The invention further provides a preparation process of the automatic refrigeration constant-temperature ice bag, which comprises the following steps:

filling water into the inner bag, and sealing;

the inner bag, the refrigerant and the cold storage agent are filled in the outer bag and sealed.

The preparation process of the automatic refrigeration constant-temperature ice bag is simple in preparation process, low in preparation cost and suitable for popularization and application.

For a better understanding and practice, the invention is described in detail below with reference to the accompanying drawings.

Drawings

Fig. 1 is a schematic structural view of a preferred structure of the automatic refrigerating constant temperature ice bag of the present invention.

Detailed Description

The terms of orientation of up, down, left, right, front, back, top, bottom, and the like, referred to or as may be referred to in this specification, are defined relative to the configuration shown in the figures, and are relative concepts. Therefore, it may be changed according to different positions and different use states. Therefore, these and other directional terms should not be construed as limiting terms.

The implementations described in the exemplary embodiments below are not intended to represent all implementations consistent with the present disclosure. Rather, they are merely examples of methods consistent with certain aspects of the present disclosure, as detailed in the appended claims.

The terminology used in the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in this disclosure and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.

Referring to fig. 1, fig. 1 is a schematic structural view of a preferred structure of an automatic refrigerating and constant temperature ice bag according to the present invention.

The automatic refrigeration constant temperature ice bag comprises an outer bag 1, wherein an inner bag 2, a refrigerant 3 and a coolant are arranged in the outer bag 1, and the inner bag 2 is hermetically filled with water. The inner bag 2, the refrigerant 3 and the coolant are arranged in the outer bag 1, after the inner bag 2 is pinched to be broken, the water in the inner bag 2 flows out to fully contact with the refrigerant 3, so that the temperature can be quickly reduced, and after the temperature is reduced, the coolant is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag 1 is kept in a low-temperature state for a long time; the automatic refrigeration constant temperature ice bag has small volume, light weight, portability, convenient use and random access, and can be provided with different numbers of ice bags according to the number and the volume of medical biological products.

Specifically, the outer bag 1 is a sealed composite film bag. The composite film bag has stable structure and low cost.

The inner bag 2 is a sealed plastic bag. The plastic bag is convenient to break by pinching and has low cost.

Preferably, a non-woven fabric bag 4 is arranged in the outer bag 1, and the coolant is filled in the non-woven fabric bag 4. The non-woven fabric bag 4 can facilitate the infiltration of the solution, so that the coolant is more fully dissolved in the solution.

The outer bag 1 of this example had a size of 25 cmX12.5cm.

The specification of the inner bag 2 is 12cmX8 cm.

The specification of the non-woven cloth bag 4 is 8cmX6 cm.

The outer bag 1, the inner bag 2 and the non-woven bag 4 are designed into the specifications, so that the ice bag has small volume, light weight, portability, convenient use and low production cost.

The refrigerant 3 of the present embodiment is preferably selected from carbamide. The carbamide can absorb heat and refrigerate quickly when dissolved in water, so that the temperature is quickly reduced to about 2 ℃, and the carbamide has low price and high safety, and can reduce the production cost and ensure the safety.

The cold-storage agent is preferably sodium polyacrylate. The sodium polyacrylate is a high molecular compound with hydrophilic and hydrophobic groups, is slowly dissolved in water to form extremely viscous transparent gel, so that the constant temperature is kept for a long time, the temperature is conveniently controlled to be 2-8 ℃, the cost of the sodium polyacrylate is low, the sodium polyacrylate is safe, and the manufactured ice bag is cheap, high in quality and safe.

The refrigerant 3, the water and the coolant are 105 parts, 100 parts and 5 parts by mass respectively. The refrigerant 3, the water and the coolant are arranged according to the mass parts, so that the refrigeration and constant temperature effects of the ice bag can be ensured while materials are saved and the volume is reduced.

The refrigerant 3, water, and coolant of the present embodiment are respectively set to 105g, 100g, and 5 g.

The invention discloses a using method of an automatic refrigeration constant-temperature ice bag, which comprises the following steps:

the inner bag 2 is broken by pinching, water in the inner bag 2 flows out and is fully contacted with the solid of the refrigerant 3, and the temperature is rapidly reduced to 2 ℃. Shaking the ice bag to make the coolant in the non-woven bag 4 contact with the solution to form gel, storing the gel in the ice bag to reach the biological reagent refrigeration temperature 2^-And (4) putting the cold storage boxes at the temperature of 8 ℃, and configuring different quantities according to the goods and the volume of the cold storage boxes. After once use, the ice bag can be used as a constant temperature ice bag and put into a refrigerator for cold storage and repeated use.

The coolant of the automatic refrigeration constant temperature ice bag of the invention ensures that the constant temperature is kept for a long time, and is convenient for temperature control and transportation. The automatic refrigeration constant-temperature ice bag has the cost of about 2 yuan/bag, is cheap and good, and has the transportation cost of about 1/10 of the cost of a cold chain, which is the cost of common express delivery.

Note that:

1. if the outer package is damaged and the content overflows, the package can not be used.

2. If the product is accidentally damaged and the contents are stained on the skin or eyes, the product can be cleaned with clear water.

3. Storage conditions are as follows: storing in a cool and dry place.

In order to prove the effect of the automatic refrigerating constant-temperature ice bag, the following experiments were carried out using the commercially available ice bag and the components in the automatic refrigerating constant-temperature ice bag of the present invention:

and (3) analyzing an experimental result: experiments carried out by using the components in the automatic refrigeration constant-temperature ice bag can rapidly reduce the temperature to below 2 ℃ within 90 seconds, the temperature reduction time and temperature are obviously better than those of common ice bags or similar mixtures purchased in the market, the raw materials are safe, and the method is not limited by the national purchase policy.

The automatic refrigeration constant temperature ice bag of the invention is compared with the similar ice bag of another applied patent, and the list is as follows:

compared with the prior art, the automatic refrigeration constant-temperature ice bag has the advantages that the inner bag, the refrigerant and the cold storage agent are arranged in the outer bag, after the inner bag is pinched broken, water in the inner bag flows out to be fully contacted with the refrigerant, so that the temperature can be quickly reduced, and after the temperature is reduced, the cold storage agent is further dissolved in a low-temperature solution to form gel, so that the temperature control effect is achieved, and the temperature in the outer bag is kept in a low-temperature state for a long time; the automatic refrigeration constant-temperature ice bag has small volume, light weight, portability, convenient use and convenient taking at any time, and can be provided with ice bags with different quantities according to the quantity and the volume of reagents. The automatic refrigeration constant temperature ice bag has the characteristics of simple structure, small volume, convenient use and the like.

The automatic refrigeration constant temperature ice bag has the beneficial effects that:

1. the patient benefits.

Due to the high cost of cold chain transportation of biological products, such cost is transferred to patients, which increases the economic burden and mental burden of patients. Some companies are on the other hand not 2 due to the high cost of cold chain transportation^-The transportation of medical biologicals between 8 ℃ like "vaccine" events seriously jeopardizes the health of the patient. The automatic refrigeration constant-temperature ice bag can help some patients to transport medical biological products in a cold chain, such as insulin in the cold chain of diabetic patients.

2. The hospital benefits.

Due to the high cost of cold chain transportation of biological products, such costs are also transferred to hospitals, which increases the cost and the medical insurance payment burden of hospitals. If the cold chain transportation temperature of the medical biological product is unqualified, medical accidents can be caused, and the reputation of a hospital is influenced. In addition, the medical biological products are frequently transported between the pharmacy and the department in the hospital by cold chain transportation of serum, biological medicines and the like.

3. The manufacturing enterprise benefits.

The automatic refrigeration constant-temperature ice bag is low in price and convenient to use, and reduces the cold chain transportation cost of production enterprises.

The preparation process of the automatic refrigeration constant temperature ice bag comprises the following steps:

water is filled in the inner bag 2 and is sealed;

the inner bag 2, the refrigerant 3 and the cold storage agent are arranged in the outer bag 1 and sealed.

Specifically, 100 ml of water is filled in a plastic bag, and the plastic bag is sealed to form the inner bag 2.5 g of coolant (sodium polyacrylate) is filled in the non-woven cloth bag 4 and sealed. 105g of refrigerant 3 (carbamide) is filled in the composite film bag, and then the inner bag 2 and the non-woven bag 4 are put in and sealed to form the outer bag 1.

The preparation process of the automatic refrigeration constant-temperature ice bag is simple in preparation process, low in preparation cost and suitable for popularization and application.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.