阅读说明：本技术 一种临床医学用血浆采集方法及装置 (Plasma collection method and device for clinical medicine ) 是由 陈玟荪 于 2019-10-16 设计创作，主要内容包括：本发明涉及血液采集技术领域,一种临床医学用血浆采集方法及装置,包括以下步骤:将采血针连接到全血收集外管上；使用采血针进行穿刺,通过按压推压组件进行全血采集,共采集3ml—5ml全血到全血收集外管中；手持全血采集外管左右摇晃20s—40s,使内部全血与抗凝剂充分混合；将全血收集外管放置在放置架上静置4min—6min,使用推压组件对全血进行加压过滤,并使过滤得到的血浆收集到血浆采集管中；将血浆采集管取下,然后密封待用。本发明流程简单,便于使用,可以有效提高血浆的采集效率,减轻医护人员的劳动量。(The invention relates to the technical field of blood collection, in particular to a method and a device for collecting plasma for clinical medicine, which comprises the following steps of connecting a blood collecting needle to a whole blood collecting outer tube; puncturing by using a blood taking needle, collecting whole blood by pressing a pushing and pressing assembly, and collecting 3-5 ml of whole blood into a whole blood collecting outer tube; shaking the hand-held whole blood collection outer tube left and right for 20-40 s to fully mix the internal whole blood with the anticoagulant; placing the whole blood collection outer tube on a placing rack for standing for 4-6 min, performing pressure filtration on the whole blood by using a pushing assembly, and collecting plasma obtained by filtration into a plasma collection tube; the plasma collection tube is removed and then sealed for use. The invention has simple flow and convenient use, can effectively improve the collection efficiency of blood plasma and reduce the labor amount of medical personnel.)

1. A method for collecting plasma for clinical medicine is characterized in that: comprises the following steps of (a) carrying out,

connecting a blood collection needle to the whole blood collection outer tube;

performing venipuncture by using a blood taking needle, collecting whole blood by pressing a pushing assembly, and collecting 3-5 ml of whole blood into a whole blood collecting outer tube;

shaking the hand-held whole blood collection outer tube left and right for 20-40 s to fully mix the internal whole blood with the anticoagulant;

standing the whole blood collection outer tube for 4-6 min, performing pressure filtration on the whole blood by using a pushing assembly, and collecting plasma obtained by filtration into a plasma collection tube;

the plasma collection tube is removed and then sealed for use.

2. The acquisition method according to claim 1, characterized in that: the anticoagulant is pre-loaded into the whole blood collection tube.

3. The acquisition method according to claim 1, characterized in that: the pushing assembly is arranged inside the whole blood collection outer tube, whole blood can enter the whole blood collection outer tube by pressing the pushing assembly, and the pushing assembly can automatically pressurize the whole blood collection outer tube after being released.

4. The acquisition method according to claim 1, characterized in that: the plasma collection tube and the whole blood collection outer tube are connected by a luer connector.

5. The utility model provides a clinical medicine uses plasma collection system which characterized in that: comprising a whole blood collection outer tube and a pushing assembly, the pushing assembly is positioned inside the whole blood collection outer tube, the front end of the whole blood collection outer tube is provided with a blood drawing port, the inner side of the hemospasia opening is provided with a one-way valve, the front end of the whole blood collection outer tube is also provided with a filtering opening, the blood filtering membrane is placed in the filtering port, the plasma collecting tube is arranged outside the filtering port, the pushing and pressing assembly comprises a sealing gasket, a first push rod and a second push rod, the first push rod can be driven to move reversely by pressing the second push rod, so that the first push rod can drive the sealing gasket to move to form negative pressure in the whole blood collecting outer tube, and a repressing device is also arranged between the first push rod and the second push rod, and the repressing device can drive the first push rod to move to the initial position when the second push rod is not pressed.

6. A clinical medical plasma collection device according to claim 5, wherein: the inner side of one end of the second push rod is provided with a gear, the other end of the second push rod is provided with a pressing sheet, the surface of the first push rod is provided with a rack corresponding to the gear, and the gear is meshed with the rack.

7. The clinical medical plasma collection device according to claim 6, wherein: the repressing device is a spring, one end of the spring is fixed on the first push rod, and the other end of the spring is arranged on the second push rod.

8. A clinical medical plasma collection device according to claim 5, wherein: the outer side of the whole blood collection outer tube is provided with a clamping part.

9. A clinical medical plasma collection device according to claim 5, wherein: the rack is provided with an upper support and a lower support.

10. A clinical medical plasma collection device according to claim 5, wherein: the plasma collecting tube comprises a tube body and a tube plug.

Technical Field

The invention relates to the technical field of blood collection, in particular to a method and a device for collecting plasma for clinical medicine.

Background

Blood specimens used in clinical examinations in medical institutions are generally obtained by collecting blood from veins, arteries or extremities (finger tips, heels or earlobes) of the human body, and the types of blood specimens are classified into whole blood, serum and plasma. The blood plasma is light yellow liquid without blood visible components after blood is subjected to anticoagulation treatment and natural precipitation or centrifugation after being separated from the body. The plasma sample has wide application in clinical experiment, and may be used in measuring biochemical components, immunological indexes, blood coagulation function, gene analysis, etc. of human blood.

The traditional plasma collection is mostly to collect whole blood and then obtain plasma through centrifugal precipitation. Because the centrifuge is heavy, the whole blood can only be stored and then taken back to a laboratory for plasma collection, so that the time consumption is long, clinical disease treatment is easily delayed, and the whole blood collected by the centrifugation method is more and more not suitable for the detection requirement of POCT (point of care testing) along with the improvement of the clinical treatment requirement. Meanwhile, when collecting the plasma samples of a plurality of people, if the plasma samples are collected by a centrifugal method, whole blood needs to be collected one by one, and after the whole blood samples are completely collected, the whole blood samples are collected by centrifugation, so that the collection efficiency of the plasma is reduced, and the labor amount of medical staff is increased.

Disclosure of Invention

The invention aims to provide a plasma collecting method and a device for clinical medicine, which are used for solving the problems of time consumption and low efficiency of the existing plasma collecting method.

In order to achieve the purpose, the invention adopts the following technical scheme:

a plasma collecting method for clinical medicine comprises the steps of attaching a blood collection needle to a whole blood collection outer tube; performing venipuncture by using a blood taking needle, collecting whole blood by pressing a pushing assembly, and collecting 3-5 ml of whole blood into a whole blood collecting outer tube; shaking the hand-held whole blood collection outer tube left and right for 20-40 s to fully mix the internal whole blood with the anticoagulant; standing the whole blood collection outer tube for 4-6 min, performing pressure filtration on the whole blood by using a pushing assembly, and collecting plasma obtained by filtration into a plasma collection tube; the plasma collection tube is removed and then sealed for use.

Furthermore, the anticoagulant is pre-loaded into the whole blood collection outer tube, and is not required to be added before being used, so that the operation flow of collecting the plasma is simplified to a greater extent, and the pollution of the outside to the whole blood is also avoided.

Further, it installs to bulldoze the subassembly inside the outer tube is collected to whole blood, through pressing it can make whole blood get into to bulldoze the subassembly in the outer tube is collected to whole blood, the release back it can be automatic right to bulldoze the subassembly whole blood and collect the outer tube pressurization to can thoroughly liberate medical personnel's both hands in the pressurization filtration stage, make it can operate other work, both shortened medical personnel's operating time greatly, alleviateed medical personnel's the amount of labour again.

Further, the plasma collecting tube and the whole blood collecting outer tube are connected through a luer connector, so that the connection is tighter, and leakage can be prevented.

In addition, the invention also provides a plasma collecting device for clinical medicine, which comprises a whole blood collecting outer tube and a pushing assembly, the pushing assembly is positioned inside the whole blood collection outer tube, the front end of the whole blood collection outer tube is provided with a blood drawing port, the inner side of the hemospasia opening is provided with a one-way valve, the front end of the whole blood collection outer tube is also provided with a filtering opening, the blood filtering membrane is placed in the filtering port, the plasma collecting tube is arranged outside the filtering port, the pushing and pressing assembly comprises a sealing gasket, a first push rod and a second push rod, the first push rod can be driven to move reversely by pressing the second push rod, so that the first push rod can drive the sealing gasket to move to form negative pressure in the whole blood collecting outer tube, and a repressing device is also arranged between the first push rod and the second push rod, and the repressing device can drive the first push rod to move to the initial position when the second push rod is not pressed.

Furthermore, a gear is arranged on the inner side of one end of the second push rod, a pressing sheet is arranged at the other end of the second push rod, a rack corresponding to the gear is arranged on the surface of the first push rod, the gear is meshed with the rack, and reverse movement of the second push rod and the first push rod can be achieved through relative movement of the gear and the gear.

Furthermore, the repressing device is a spring, one end of the spring is fixed on the first push rod, and the other end of the spring is arranged on the second push rod.

Furthermore, the whole blood collection outer tube is provided with a clamping part on the outer side, so that fingers can be used for clamping conveniently during operation.

Further, still include the rack, be provided with upper bracket and lower carriage on the rack, the upper bracket is used for placing whole blood collection outer tube, and the lower carriage is used for placing plasma collection pipe.

Further, the plasma collection tube comprises a tube body and a tube plug, and is convenient to seal and store.

The invention has the beneficial effects that:

according to the collection method, the whole blood and the anticoagulant are fully mixed, and then the blood plasma is collected in a pressurization filtering mode, so that the collection mode is simple, the time is saved, and the working efficiency is high; the collection system can accomplish whole blood collection fast through the cooperation of first push rod and second push rod by one hand, then rely on the repressurization device can accomplish the pressure filtration of whole blood automatically, can effectively simplify the flow of gathering plasma and save the time of gathering plasma, has effectively reduced the time that the disease waited for the inspection result, can effectively alleviate medical staff's the amount of labour moreover when taking a sample on a large scale.

Drawings

FIG. 1 is a flow chart of a method according to an embodiment of the present invention.

FIG. 2 is a front sectional view of an embodiment of the present invention.

Fig. 3 is a perspective view of an embodiment of the present invention.

FIG. 4 is a front sectional view of the embodiment of the present invention in a placed state.

FIG. 5 is a schematic view of a plasma collection tube according to an embodiment of the present invention.

In the figure: the blood collection device comprises a whole blood collection outer tube 1, a filtration port 11, a blood drawing port 12, a one-way valve 13, a blood plasma collection tube 2, a tube body 21, a tube plug 22, a pushing assembly 3, a sealing gasket 31, a first push rod 32, a gear 33, a second push rod 34, a pressing sheet 35, a clamping part 4, a blood filtration membrane 5, a spring 6, a placing frame 7, an upper bracket 71 and a lower bracket 72.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.

It should be noted that "first" and "second" in this specification are used only for distinguishing different components, and do not indicate a specific order or sequence; furthermore, the terms "one end", "the other end", "inside", "outside", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

Referring to fig. 1 to 5, a plasma collection method for clinical medicine includes the steps of,

s1, connecting the blood taking needle to the whole blood collecting outer tube 1;

s2, performing venipuncture by using a blood taking needle, collecting whole blood by pressing the pushing and pressing component 3, collecting 3-5 ml of whole blood into the whole blood collecting outer tube 1, and ensuring sufficient plasma testing dosage;

s3, shaking the whole blood collection outer tube 1 left and right for 20-40S by hand to fully mix the whole blood and the anticoagulant inside;

s4, placing the whole blood collection outer tube 1 on a placing rack 7 to stand still for 4-6 min, using a pushing assembly 3 to perform pressure filtration on the whole blood, and collecting the filtered plasma into a plasma collection tube 2;

s5, the plasma collecting tube 2 is taken down and sealed for standby.

In this case, the anticoagulant is pre-loaded into the whole blood collection tube 1 in advance without being separately added. The pushing and pressing component 3 is arranged inside the whole blood collection outer tube 1, negative pressure can be formed inside the whole blood collection outer tube 1 by pressing the pushing and pressing component 3, whole blood enters, after the pushing and pressing component 3 is released, the pushing and pressing component 3 can reset automatically, whole blood pressurization and filtration can be completed in the process, and filtered plasma enters the plasma collection tube 2. Wherein, the blood plasma collecting tube 2 is connected with the whole blood collecting outer tube 1 through a luer joint, and is convenient to pick.

Referring to fig. 2-5, a plasma collecting device for clinical medicine obtained by the above collecting method comprises a whole blood collecting outer tube 1 and a pushing assembly 3, wherein the pushing assembly 3 is located inside the whole blood collecting outer tube 1, a blood drawing port 12 is arranged at the front end of the whole blood collecting outer tube 1, a one-way valve 13 is arranged inside the blood drawing port 12, the one-way valve 13 can allow whole blood to enter the inside of the whole blood collecting outer tube 1, a filtering port 11 is further arranged at the front end of the whole blood collecting outer tube 1, a blood filtering membrane 5 is arranged in the filtering port 11, the blood filtering membrane 5 is used for filtering red blood cells and other substances in the whole blood, a plasma collecting tube 2 is arranged outside the filtering port 11, the pushing assembly 3 comprises a sealing gasket 31, a first push rod 32 and a second push rod 34, a gear 33 is arranged inside one end of the second push rod 34, a pressing sheet 35 is arranged at the other end of the second push rod, and the gear 33 is meshed with the rack, the gear 33 can drive the rack to move by pressing the second push rod 34, so that the first push rod 32 is driven to move reversely, the first push rod 32 can drive the sealing gasket 31 to move to form negative pressure in the whole blood collecting outer tube 1, the spring 6 is further arranged between the first push rod 32 and the second push rod 34, one end of the spring 6 is fixed on the first push rod 32, the other end of the spring is arranged on the second push rod 34, and the first push rod 32 can be driven to move to the initial position when the second push rod 34 is not pressed.

Wherein, the whole blood collecting outer tube 1 is provided with a clamping part 4 on the outer side. The placing frame 7 is divided into an upper bracket 71 and a lower bracket 72, wherein the upper bracket 71 is used for hanging the whole blood collection outer tube 1, and the lower bracket 72 is used for accommodating the plasma collection tube 2. The plasma collecting tube 2 is divided into a tube body 21 and a tube plug 22, and the tube plug 22 can be covered on the tube body 21 after plasma is contained, so that the plasma collecting tube is convenient to store and place.

When in use, the whole blood collecting outer tube 1 is held by hand, the blood taking needle is arranged on the blood drawing port 12, then the arm of a patient can be pressed by the tourniquet, and the vein is selected and disinfected. Then, the blood collection tube 1 is punctured by the blood collection needle, after the blood collection needle is inserted into a blood vessel, the blood collection needle is stably held by one hand, the whole blood collection tube 1 is held by the other hand, the index finger and the middle finger are clamped on the clamping part 4, the pressing piece 35 is pressed by the thumb, the second push rod 34 is pressed to move towards the first push rod 32, the gear 33 inside the second push rod 34 is driven by the second push rod 34 to rotate, the rack meshed with the second push rod moves towards the direction opposite to the direction of the second push rod 34, the first push rod 32 drives the sealing gasket 31 to move outwards, negative pressure is formed inside the whole blood collection tube 1, and blood can enter the whole blood collection tube 1 through the blood collection needle.

Then the blood taking needle is pulled out, and then the whole blood collection outer tube 1 is held by hand to uniformly shake, so that the whole blood and the pre-rotated anticoagulant in the whole blood collection outer tube 1 are fully mixed and contacted to prevent the blood from coagulating. And then placing the whole blood collection outer tube 1 on a placing rack 7 for standing. When the blood collection tube is in a standing state, the pressure of the spring 6 is released, so that the first push rod 32 and the second push rod 34 start to restore to the initial positions, the sealing gasket 33 starts to press the whole blood inwards, the one-way valve 13 in the blood outlet 12 can ensure that the whole blood does not overflow from the blood drawing port 12 when the pressure is applied, the whole blood is filtered through the blood filtering membrane 5 in the filtering port 11, the filtered blood plasma flows into the tube body 21 of the blood collection tube 2 connected to the outside of the filtering port, and the tube body 21 can be pulled down for use or the tube plug 22 is covered for storage and standby.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.