阅读说明：本技术 一种抗菌消炎的吡啶酮组合物及包含其的化妆品 (Antibacterial and anti-inflammatory pyridone composition and cosmetic containing same ) 是由 陈晓辉 蔡建 薛天辉 秦莉锦 白丽静 于 2019-11-16 设计创作，主要内容包括：本发明公开了一种抗菌消炎的吡啶酮组合物及包含其的化妆品。所述吡啶酮组合物包含以下组分：吡啶酮乙醇胺盐9.0至11.0重量份；三乙酸甘油酯2.5至5.5重量份；以及环氧大豆油1.0至3.0重量份。根据本发明的吡啶酮组合物能够用于化妆品,特别是毛发化妆品和肤用化妆品中,高效且全面地抑制和杀灭各种致病细菌和真菌,预防和消灭致炎因子、去屑止痒、祛痘除斑。(The invention discloses an antibacterial and anti-inflammatory pyridone composition and a cosmetic containing the same. The pyridone composition comprises the following components: 9.0 to 11.0 parts by weight of pyridone ethanolamine salt; 2.5 to 5.5 parts by weight of glyceryl triacetate; and 1.0 to 3.0 parts by weight of epoxidized soybean oil. The pyridone composition can be used in cosmetics, particularly hair cosmetics and skin cosmetics, can effectively and comprehensively inhibit and kill various pathogenic bacteria and fungi, prevent and eliminate inflammatory factors, remove dandruff and relieve itching, and remove acne and spots.)

1. An antibacterial and anti-inflammatory pyridone composition, comprising the following components:

9.0 to 11.0 parts by weight of pyridone ethanolamine salt;

2.5 to 5.5 parts by weight of glyceryl triacetate; and

1.0 to 3.0 parts by weight of epoxidized soybean oil.

2. The pyridone composition of claim 1, wherein said pyridone composition comprises the following components:

9.5 to 10.5 parts by weight of pyridone ethanolamine salt;

3.5 to 4.5 parts by weight of glyceryl triacetate; and

1.5 to 2.5 parts by weight of epoxidized soybean oil.

3. The pyridone composition of claim 1, wherein said pyridone composition comprises the following components:

10.0 parts by weight of pyridone ethanolamine salt;

4.0 parts by weight of glyceryl triacetate; and

2.0 parts of epoxidized soybean oil.

4. The pyridone composition according to any one of claims 1 to 3, characterized in that the pyridone composition comprises a hydroxyl compound, wherein the hydroxyl compound is selected from the group consisting of 1, 3-propanediol, methylpropanediol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 2-octanediol, 1, 2-decanediol, 1, 5-pentanediol, 1, 6-hexanediol, 1, 8-octanediol, 1, 2-decanediol, ethylhexylglycerol, hexyloxy-propane-1, 2-diol, heptyloxy-propane-1, 2-diol, octyloxy-propane-1, 2-diol, 3-phenoxy-propane-1, 2-diol, 3-benzyloxy-propane-1, 2-diol, 3-phenylethoxy-propane-1, 2-diol, 3-phenylphenoxy-propane-1, 2-diol, 3-methylbenzyloxy-propane-1, 2-diol, sorbitol caprylate, triclosan, chitosan, farnesol, 2-butyloctanoic acid, 2-benzylheptan-1-ol, glycerol monolaurate, zinc pyrithione, thymol, eugenol, benzyl alcohol, 2-phenylethanol, 3-phenylpropanol, 2-phenoxyethanol, 1-phenoxy-propane-2-ol, 3-phenoxypropanol, benzyloxymethanol.

5. The pyridone composition of claim 4, wherein the weight ratio of the total pyridone ethanolamine salt, glyceryl triacetate, and epoxidized soybean oil to the hydroxy compound is from 0.5:99.5 to 99.5: 0.5.

6. A pyridone composition according to any one of claims 1 to 3, characterized in that it comprises a bactericidal adjuvant selected from the group consisting of octanoyl hydroxamic acid, climbazole, N' - (decan-1, 10-diyldipyridin-1-yl-4-ylidene) -dioctylamine-1-dihydrogenammonium chloride, benzoic acid and p-hydroxybenzoic acid, benzoic esters andparabens, benzoates and parabens, benzyl benzoate, propionic acid and salts thereof, salicylic acid and salts thereof, 2, 4-hexadienoic acid and salts thereof, levulinic acid and salts thereof, anisic acid and salts thereof, perillic acid and salts thereof, cinnamic acid and salts thereof, formaldehyde and paraformaldehyde, 4-hydroxybenzaldehyde, o-, m-and p-anisaldehyde, cinnamaldehyde, cinnamyl alcohol, 2-hydroxydiphenyl ether and salts thereof, 2-zinc-pyridine sulfide nitroxide, inorganic sulfites and bisulfites, sodium iodate, chlorobutanol, 4-ethylmercury- (II) 5-amino-1, 3-bis (2-hydroxybenzoic acid) salts and esters, salts and esters of benzoic acid and parabens, benzoic acid and salts of benzoic acid, salicylic acid and salts thereof, 2, 4-hexad, Dehydroacetic acid, formic acid, 1, 6-bis (4-amidino-2-bromophenoxy) -N-hexane and salts thereof, ethylmercury- (II) -sodium thiosalicylic acid, phenylmercuric acid and salts thereof, 10-undecylenic acid and salts thereof, 5-amino-1, 3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine, 5-bromo-5-nitro-1, 3-dioxane, 2-bromo-2-nitro-1, 3-propanediol, 2, 4-dichlorobenzyl alcohol, N- (4-chlorophenyl) -N ' - (3, 4-dichlorophenyl) -urea, 4-chloro-m-cresol, 2,4,4' -trichloro-2 ' -hydroxy-diphenyl ether, sodium ethylmercuric oxide- (II) -2-methyl-hexahydro-l, 5-bromo-5-nitro-1, 3-dioxane, 2-bromo-2-nitro-1, 3-propanediol, 4-chloro-3, 5-dimethylphenol, 1' -methylene-bis (3- (1-hydroxymethyl-2, 4-dioxoimidazolidin-5-yl) urea), poly- (hexamethylenebiguanide) hydrogen chloride, (benzyloxymethoxy) -methanohexamethylenetetramine, 1- (3-chloroallyl) -3,5, 7-triaza-1-azoie-tricyclo-decane chloride, 1- (4-chlorophenoxy) -1- (1H-imidazol-1-yl) -3, 3-dimethyl-2-butanone, 1, 3-bis- (hydroxymethyl) -5, 5-dimethyl-2, 4-imidazolidinedione, methyl-ethyl-1-carboxylate, methyl-1-hydroxy-5-methyl-2, 4, 1, 2-dibromo-2, 4-dicyanobutane, 2' -methylene-bis (6-bromo-4-chlorophenol), bromochlorophene, 5-chloro-2-methyl-3 (2H) -isothiazolinone, a mixture of 2-methyl-3 (2H) -isothiazolinone and magnesium chloride and magnesium nitrate, 2-octyl-2H-isothiazolin-3-one, 1, 2-benzisothiazol-3 (2H) -one, 2-benzyl-4-chlorophenol, 3- (4-chlorophenoxy) -1, 2-propanedione (chlorophenol ether), 2-chloroacetamide, chlorhexidine, acetic acid, chlorhexidine, gluconic acid, chlorhexidine hydrochloride, N-alkyl (C)₁₂-C₂₂) Trimethyl-ammonium bromide and N-alkyl (C)₁₂-C₂₂) Trimethyl-ammonium chloride, 4-dimethyl-1, 3-oxazolidine, N-hydroxymethyl-N- (1, 3-di (hydroxymethyl) -2, 5-dioxoimidazolidin-4-yl) -N' -hydroxy-methylurea, 1, 6-bis (4-amidino-benzene)Oxy) -n-hexane and its salts, glutaraldehyde, 5-ethyl-1-aza-3, 7-dioxabicyclo [ 3.3.0%]Octane, 3- (4-chlorophenoxy) -1, 2-propanediol, alkyl- (C)₈-C₁₈) -dimethyl-benzyl-ammonium chloride, alkyl- (C)₈-C₁₈) -dimethyl-benzylammonium bromide, alkyl- (C)₈-C₁₈) -dimethyl-benzyl-saccharinate, benzyl hemi-formaldehyde, 3-iodo-2-propynylbutyl carbamate, sodium hydroxymethyl-aminoacetate, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethyl glycinate, DMDM hydantoin, tropolone, (ethylenedioxy) dimethanol, 2-bromo-2- (bromomethyl) glutaronitrile, N- (3-aminopropyl) -N-dodecylpropane-1, 3-diamine, α ', α' -trimethyl-1, 3, 5-triazine-1, 3,5(2H,4H,6H) -triol, pyridine-2-thiol-1-oxide, sodium salt, tetrahydro-1, 3,4, 6-tetrakis (hydroxymethyl) imidazo [4,5-d]Imidazole-2, 5(1H,3H) -dione, 1, 3-bis (hydroxymethyl) -1- (1,3, 4-tris (hydroxymethyl) -2, 5-dioxoimidazolidin-4-yl) urea (diazoalkylimidazolium urea), 1, 3-bis (hydroxymethyl) -5, 5-dimethylimidazolidine-2, 4-dione, 3-acetyl-2-hydroxy-6-methyl-4H-pyran-4-one, cetylpyridinium chloride, 2, 4-hexadienyloxyoxime acid and mixtures thereof, antimicrobial peptides, acetophenone and derivatives thereof, chlorphenesin, diamidine and salts thereof, cymene and derivatives thereof, o-phenylphenol and salts thereof.

7. The pyridone composition of claim 6, wherein the weight ratio of the total weight of pyridone ethanolamine salt, glyceryl triacetate, and epoxidized soybean oil to the germicidal additive is from 0.5:99.5 to 99.5: 0.5.

8. Use of a pyridone composition according to any one of claims 1 to 7 in cosmetics.

9. A cosmetic comprising the pyridone composition of any one of claims 1 to 7 and a cosmetically acceptable adjuvant.

10. The cosmetic according to claim 9, wherein the cosmetic is a hair cosmetic or a skin cosmetic.

Technical Field

The invention relates to the field of cosmetics, and in particular relates to an antibacterial and anti-inflammatory pyridone composition and a cosmetic containing the same.

Background

Pyridone compounds, such as pyridone ethanolamine salt, are novel anti-dandruff antipruritic agents, have broad-spectrum killing and inhibiting effects on fungi and mold, have good therapeutic effects on tinea pedis and tinea manuum, have special body odor removing effects, and can be used as antiseptics in cosmetics and bactericides in toilet soaps. The principle of the pyridone ethanolamine salt dandruff removal is that abnormal reproduction of malassezia furfur which causes excessive dandruff and scalp itch can be killed and inhibited, and the pyridone ethanolamine salt dandruff removal agent has an antioxidant effect and an oxide decomposition capability, so that external factors generated by dandruff can be fundamentally blocked, the aim of radically treating the dandruff is fulfilled, and itching can be effectively relieved. Under the condition of the same amount or less addition amount, the anti-dandruff and anti-itching effect is obviously better than that of other anti-dandruff and anti-itching agents.

In addition, the pyridone ethanolamine salt has excellent solubility and compounding performance, and cannot generate precipitation or layering phenomenon when being mixed with other cosmetic raw materials; has extremely low irritation, does not cause the problems of alopecia, hair breakage and the like, and has better safety than similar dandruff-removing and itching-relieving products. Therefore, the pyridone ethanolamine salt is a multifunctional anti-dandruff and anti-itching bactericide, is widely applied to hair care products, bath foam, cosmetics and washing products, is the only anti-dandruff and anti-itching agent which can be used for no-wash hair products such as hair cream, hair gel, mousse, hair dye and the like at present, and has the following conventional dosage: 0.3-1.0% of anti-dandruff shampoo, 0.3-1.0% of anti-dandruff shampoo and 0.1-0.3% of hair conditioner.

Disclosure of Invention

[ problem ] to

However, most studies on the efficacy of pyridone ethanolamine salt in resisting malassezia bacteria are now conducted, and the skilled person would like to develop cosmetic compositions based on the pyridone ethanolamine salt, which can inhibit and kill other pathogenic bacteria and fungi more effectively and comprehensively to prevent and eliminate inflammatory factors, remove dandruff, relieve itching, remove acne and spots.

[ solution ]

In view of the defects of the prior art, the invention aims to provide an antibacterial and anti-inflammatory pyridone composition which can effectively inhibit and kill pathogenic bacteria and fungi, diminish inflammation, remove acnes and remove spots.

To achieve the above objects, one aspect of the present invention provides an antibacterial and anti-inflammatory pyridone composition comprising the following components:

9.0 to 11.0 parts by weight of pyridone ethanolamine salt;

2.5 to 5.5 parts by weight of glyceryl triacetate; and

1.0 to 3.0 parts by weight of epoxidized soybean oil.

In the above pyridone composition, the pyridone ethanolamine salt, chemical name: 1-hydroxy-4-methyl-6- (2,4,4, trimethylpentyl) -2-pyridone ethanolammonium salt of formula: c₁₄H₂₃NO₂·C₂H₇NO, molecular weight: 298.43, white or pale yellow crystalline powder, with very slight characteristic odor.

Triacetin, CAS No.: 102-76-1, formula: c₉H₁₄O₆The essence is colorless oily liquid, has faint fruity and sweet meat taste, has bitter taste at low concentration, is usually used in a daily chemical essence formula, is mainly used as a fragrance fixing agent, and has no report of obvious sterilization effect.

Epoxidized soybean oil, which is a product prepared by oxidizing soybean oil, is a light yellow viscous oily liquid at normal temperature, has excellent thermal stability and light stability, and also has excellent water resistance and oil resistance, can endow products with good mechanical strength, weather resistance and electrical property, is nontoxic, and has no obvious bactericidal effect.

However, the invention discovers that the capability of pyridone ethanolamine salt for inhibiting and killing pathogenic bacteria and fungi can be obviously improved by compounding the three components, and an obvious synergistic effect is generated. The pyridone composition according to the present invention can have a significantly reduced minimum inhibitory concentration at the same amount as the pyridone ethanolamine salt, indicating that triacetin and epoxidized soybean oil further improve the bactericidal and bacteriostatic ability of the pyridone ethanolamine salt, and the composition has excellent killing and inhibitory effects on Escherichia coli (Escherichia coli), Staphylococcus aureus (Staphylococcus aureus), Pseudomonas aeruginosa (Pseudomonas aeruginosa), Aspergillus niger (Aspergillus niger), candida albicans (Monilia or candida albicans), malassezia (pityspora), propionibacterium acnes (propionibacterium acnes), Brevibacterium epidermidis (Brevibacterium epidermidis), etc., exhibits broad-spectrum antibacterial ability, and also brings about excellent effects of removing dandruff, diminishing inflammation, relieving itching, removing acne, etc. on the above-mentioned bacteria, fungi, etc.

Preferably, in the pyridone composition of the present invention, the pyridone ethanolamine salt may be present in an amount of 9.0 to 11.0 parts by weight, preferably 9.2 to 10.8 parts by weight, 9.4 to 10.6 parts by weight, 9.6 to 10.4 parts by weight, 9.8 to 10.2 parts by weight, or 10.0 parts by weight; the glyceryl triacetate can be present in an amount of 2.5 to 5.5 parts by weight, preferably 2.7 to 5.3 parts by weight, 2.9 to 5.1 parts by weight, 3.1 to 4.9 parts by weight, 3.3 to 4.7 parts by weight, 3.5 to 4.5 parts by weight, 3.7 to 4.3 parts by weight, 3.9 to 4.1 parts by weight, or 4.0 parts by weight; and the epoxidized soybean oil may be present in an amount of 1.0 to 3.0 parts by weight, preferably 1.2 to 2.8 parts by weight, 1.4 to 2.6 parts by weight, 1.6 to 2.4 parts by weight, 1.8 to 2.2 parts by weight, or 2.0 parts by weight. Within the above range, the pyridone composition according to the present invention can sufficiently exhibit broad-spectrum killing and bacterial fungus-inhibiting capabilities with a low usage amount of the pyridone ethanolamine salt, thereby achieving the purposes of removing dandruff, relieving itching, diminishing inflammation, and removing acne.

Preferably, the antibacterial and anti-inflammatory pyridone composition according to the present invention comprises the following components:

9.5 to 10.5 parts by weight of pyridone ethanolamine salt;

3.5 to 4.5 parts by weight of glyceryl triacetate; and

1.5 to 2.5 parts by weight of epoxidized soybean oil.

More preferably, the antibacterial and anti-inflammatory pyridone composition according to the present invention comprises the following components:

10.0 parts by weight of pyridone ethanolamine salt;

4.0 parts by weight of glyceryl triacetate; and

2.0 parts of epoxidized soybean oil.

Further, the pyridone composition may further comprise a hydroxyl compound selected from the group consisting of 1, 3-propanediol, methylpropanediol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 2-octanediol, 1, 2-decanediol, 1, 5-pentanediol, 1, 6-hexanediol, 1, 8-octanediol, 1, 2-decanediol, ethylhexylglycerin, hexyloxy-propane-1, 2-diol, heptyloxy-propane-1, 2-diol, octyloxy-propane-1, 2-diol, 3-phenoxy-propane-1, 2-diol, 3-benzyloxy-propane-1, 2-diol, 3-phenylethoxy-propane-1, at least one of 2-diol, 3-phenylphenoxy-propane-1, 2-diol, 3-methylbenzyloxy-propane-1, 2-diol, sorbitol octanoate, triclosan, chitosan, farnesol, 2-butyloctanoic acid, 2-benzylheptan-1-ol, glycerol monolaurate, zinc pyrithione, thymol, eugenol, benzyl alcohol, 2-phenylethanol, 3-phenylpropanol, 2-phenoxyethanol, 1-phenoxy-propane-2-ol, 3-phenoxypropanol, and benzyloxymethanol, but the present invention is not limited thereto.

Preferably, the weight ratio of the total weight of the pyridone ethanolamine salt, glyceryl triacetate, and epoxidized soybean oil to the hydroxyl compound in the pyridone composition can be from 0.5:99.5 to 99.5:0.5, preferably from 1:99 to 99:1, from 10:90 to 90:10, from 30:70 to 70:30, more preferably 50: 50.

Further, the pyridone composition may further comprise a bactericidal adjuvant selected from the group consisting of octanoyl hydroxamic acid, climbazole, N' - (decan-1, 10-diyldipyridin-1-yl-4-ylidene) -dioctylamine-1-dihydroammonium chloride (octenidine hydrochloride), benzoic acid and p-hydroxybenzoic acid, benzoic acid esters and p-hydroxybenzoic acid esters, benzoic acid salts and p-hydroxybenzoic acid salts, benzyl benzoate, propionic acid and its salts, salicylic acid and its salts, 2, 4-hexadienoic acid (sorbic acid) and its salts, levulinic acid and its salts, anisic acid and its salts, perillic acid and its salts, cinnamic acid and its salts, formaldehyde and paraformaldehyde, 4-hydroxybenzaldehyde, o-, m-and p-anisaldehyde, cinnamaldehyde, cinnamyl alcohol, 2-hydroxydiphenyl ether and its salts, benzoic acid and its salts, and mixtures thereof, 2-zinc-pyridium sulfide nitroxide, inorganic sulfites and bisulfites, sodium iodate, chlorobutanol, 4-ethylmercury- (II) 5-amino-1, 3-bis (2-hydroxybenzoic acid), salts and esters of 4-ethylmercury- (II) 5-amino-1, 3-bis (2-hydroxybenzoic acid), dehydroacetic acid, formic acid, 1, 6-bis (4-amidino-2-bromophenoxy) -n-hexane and its salts, the sodium salt of ethylmercury- (II) -thiosalicylic acid, phenylmercuric acid and its salts, 10-undecylenic acid and its salts, 5-amino-1, 3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine, 5-bromo-5-nitro-1, 3-dioxane, 2-bromo-2-nitro-1, 3-propanediol, 2, 4-dichlorobenzyl alcohol, N- (4-chlorophenyl) -N '- (3, 4-dichlorophenyl) -urea, 4-chloro-m-cresol, 2,4,4' -trichloro-2 '-hydroxy-diphenyl ether, 4-chloro-3, 5-dimethylphenol, 1' -methylene-bis (3- (1-hydroxymethyl-2, 4-dioxoimidazolidin-5-yl) urea), poly- (hexamethylene biguanide) hydrogen chloride, (benzyloxymethoxy) -methanol hexamethylenetetramine, 1- (3-chloroallyl) -3,5, 7-triaza-1-azoie tricyclo-decane chloride, 1- (4-chlorophenoxy) -1- (1H-imidazol-1-yl) -3, 3-dimethyl-2-butanone, 1, 3-bis- (hydroxymethyl) -5, 5-dimethyl-2, 4-imidazolidinedione, 1, 2-dibromo-2, 4-dicyanobutane, 2' -methylene-bis (6-bromo-4-chlorophenol), bromochlorophene, 5-chloro-2-methyl-3 (2H) -isothiazolinone, a mixture of 2-methyl-3 (2H) -isothiazolinone and magnesium chloride and magnesium nitrate, 2-octyl-2H-isothiazol-3-one, 1, 2-benzisothiazol-3 (2H) -one, 2-benzyl-4-chlorophenol, 3- (4-chlorophenoxy) -1, 2-propanedione (chlorophenol ether), 2-chloroacetamide, chlorhexidine, acetic acid, chlorhexidine gluconate, chlorhexidine hydrochloride, N-alkyl (C)₁₂-C₂₂) Trimethyl-ammonium bromide and N-alkyl (C)₁₂-C₂₂) Trimethyl-ammonium chloride, 4-dimethyl-1, 3-oxazolidine, N-hydroxymethyl-N- (1, 3-bis (hydroxymethyl) -2, 5-dioxoimidazolidin-4-yl) -N' -hydroxy-methylurea, 1, 6-bis (4-amidino-phenoxy) -N-hexane and its salts, glutaraldehyde, 5-ethyl-1-aza-3, 7-dioxabicyclo [3.3.0]Octane, 3- (4-chlorophenoxy) -1, 2-propanediol, alkyl- (C)₈-C₁₈) -dimethyl-benzyl-ammonium chloride, alkyl- (C)₈-C₁₈) -dimethyl-benzylammonium bromide, alkyl- (C)₈-C₁₈) -dimethyl-benzyl-saccharinate, benzyl half-carbaldehyde, a carbamate3-iodo-2-propynylbutyl acid, sodium hydroxymethyl-aminoacetate, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethyl glycinate, DMDM hydantoin (DMDHYDANTOIn), tropolone, (ethylenedioxy) dimethanol, 2-bromo-2- (bromomethyl) glutaronitrile, N- (3-aminopropyl) -N-dodecylpropane-1, 3-diamine, alpha' -trimethyl-1, 3, 5-triazine-1, 3,5(2H,4H,6H) -triethanol, pyridine-2-thiol-1-oxide, sodium salt, tetrahydro-1, 3,4, 6-tetrakis (hydroxymethyl) imidazo [4,5-d []Imidazole-2, 5(1H,3H) -dione, 1, 3-bis (hydroxymethyl) -1- (1,3, 4-tris (hydroxymethyl) -2, 5-dioxoimidazolidin-4-yl) urea (diazoalkylimidazolium urea), 1, 3-bis (hydroxymethyl) -5, 5-dimethylimidazolidine-2, 4-dione, 3-acetyl-2-hydroxy-6-methyl-4H-pyran-4-one, cetylpyridinium chloride, 2, 4-hexadienyloxyoxime acid, and mixtures thereof, at least one of antibacterial peptide, acetophenone and its derivatives, chlorphenesin, dobutadine and its salts, cymene and its derivatives, o-phenylphenol and its salts, but the present invention is not limited thereto.

Preferably, in the pyridone composition, the weight ratio of the total weight of the pyridone ethanolamine salt, the glyceryl triacetate and the epoxidized soybean oil to the bactericidal adjuvant may be 0.5:99.5 to 99.5:0.5, preferably 1:99 to 99:1, 10:90 to 90:10, 30:70 to 70:30, more preferably 50: 50.

By including the above-mentioned hydroxyl compound and the bactericidal auxiliary, the pyridone composition according to the present invention can further enhance the ability to kill the above-mentioned escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, aspergillus niger, candida albicans, malassezia, propionibacterium acnes, brevibacterium epidermidis, and the like, and can also be resistant to other pathogenic bacteria, fungi, and the like.

The above pyridone composition according to the present invention can be applied to cosmetics.

Furthermore, it is another object of the present invention to provide a cosmetic comprising the pyridone composition according to the present invention and a cosmetically acceptable adjuvant.

Wherein the cosmetic can be hair cosmetic such as shampoo, rinse, nourishing hair lotion, hair styling product, permanent wave agent, Mousse (Mousse), shaving cream, etc.; or skin cosmetic such as face cream, facial mask, eye cream, face cleaning lotion, skin toner, sun cream, etc.

[ advantageous effects ]

In conclusion, the invention has the following beneficial effects:

the pyridone composition can be used in cosmetics, particularly hair cosmetics and skin cosmetics, can effectively and comprehensively inhibit and kill various pathogenic bacteria and fungi, prevent and eliminate inflammatory factors, remove dandruff and relieve itching, and remove acne and spots.

Detailed Description

The present invention will be described in further detail with reference to examples.

Source of raw materials

Pyridone ethanolamine salt with purity of 99% from Nicotiana oriental chemical Co., Ltd;

triacetin, 99% pure, available from Sigma Aldrich (Sigma-Aldrich);

epoxidized soybean oil, 99% pure, purchased from Sigma Aldrich (Sigma-Aldrich); and

o-cymene-5-ol, 99% pure, purchased from Sigma Aldrich (Sigma-Aldrich).

< example >