阅读说明：本技术 一种血管化学消融用导丝导引双层球囊导管 (Guide wire guiding double-layer balloon catheter for chemical ablation of blood vessels ) 是由 王怀杰 于 2019-10-31 设计创作，主要内容包括：本发明公开一种血管化学消融用导丝导引双层球囊导管,包括导管和沿导管外壁轴向设置的双层球囊,导管内腔体沿径向被分割成相互独立的导丝导引通道、球囊填充通道和给药通道；双层球囊包括相互包覆的内层球囊和外层球囊,内层球囊和外层球囊扩张后二者之间形成外腔体,外层球囊为疏松多孔结构,外层球囊上均匀密布有微孔；球囊扩张后,通过给药通道将药物送到外腔体,经微孔进入到球囊表面与靶血管内皮接触,精准地破坏靶血管壁；在治疗相同的靶血管情况下,与传统的化学破坏或热消融相比,可能极大地减少正常血液成分,并降低药物用量。(The invention discloses a guide wire guide double-layer balloon catheter for chemical ablation of blood vessels, which comprises a catheter and a double-layer balloon arranged axially along the outer wall of the catheter, wherein an inner cavity of the catheter is divided into a guide wire guide channel, a balloon filling channel and a drug delivery channel which are independent from each other along the radial direction; the double-layer balloon comprises an inner-layer balloon and an outer-layer balloon which are mutually coated, an outer cavity is formed between the inner-layer balloon and the outer-layer balloon after the inner-layer balloon and the outer-layer balloon are expanded, the outer-layer balloon is in a loose porous structure, and micropores are uniformly and densely distributed on the outer-layer balloon; after the saccule is expanded, the medicine is sent to the outer cavity through the medicine feeding channel, enters the surface of the saccule through the micropores and contacts with the endothelium of the target blood vessel, and the wall of the target blood vessel is accurately damaged; in the case of treating the same target blood vessel, it is possible to greatly reduce normal blood components and reduce the amount of the drug used, compared to conventional chemical destruction or thermal ablation.)

1. The utility model provides a double-deck sacculus pipe of seal wire guide for vascular chemistry ablation which characterized in that: comprises a catheter (1) and a double-layer balloon (2) arranged along the outer wall of the catheter in the axial direction, wherein the front end of the catheter (1) is a guide wire traction head, and the rear end of the catheter is connected with a connector (3); the inner cavity of the catheter (1) is divided into a guide wire guide channel (11), a balloon filling channel (12) and a drug delivery channel (13) which are independent from each other along the radial direction; the connector (3) is provided with a first interface (4), a second interface (5) and a third interface (6) which are respectively communicated with the guide wire guide channel (11), the balloon filling channel (12) and the drug administration channel (13); double-deck sacculus (2) are including inlayer sacculus (9) and outer sacculus (10) of mutual cladding, form outer cavity between the two after inlayer sacculus (9) and outer sacculus (10) expansion, form interior cavity in inlayer sacculus (9), it is isolated between two cavities, and outer sacculus (10) are loose porous structure, and evenly it has micropore (8) to gather on outer sacculus (10), sacculus filling channel (12) intercommunication in interior cavity and pipe (1), outer cavity and pipe (1) interconnection are given medicine passageway (13) intercommunication.

2. The guidewire-guided double-layer balloon catheter for vascular chemical ablation according to claim 1, wherein: micropores (8) on the outer layer saccule (10) are distributed at equal intervals.

3. The guidewire-guided double-layer balloon catheter for vascular chemical ablation according to claim 2, wherein: the outer side of the catheter is provided with developing marks (7), and the two developing marks (7) are positioned in the double-layer saccule (2) and close to the end part of the double-layer saccule (2).

4. A guidewire-guided double-layer balloon catheter for vascular chemical ablation according to any of claims 1-3, wherein: the double-layer saccule (2) is of a double-saccule structure arranged along the axial direction of the catheter (1), and the two saccules are mutually independent.

5. The guidewire-guided double-layer balloon catheter for vascular chemical ablation according to claim 4, wherein: the diameter of the catheter (1) is 5Fr-10 Fr.

6. The guidewire-guided double-layer balloon catheter for vascular chemical ablation according to claim 4, wherein: the diameter of the double-layer saccule (2) is 0.5cm-3.0cm, and the length is 3cm-10 cm.

7. The guidewire-guided double-layer balloon catheter for vascular chemical ablation according to claim 4, wherein: the volume of an outer cavity formed between the inner balloon (9) and the outer balloon (10) after the two balloons are expanded is 1.5-2.0 ml.

Technical Field

The invention relates to medical equipment, in particular to a guide wire guiding double-layer balloon catheter for chemical ablation of blood vessels.

Background

The existing interventional catheters are divided into two types according to purposes: vessel recanalization and blood flow blockage. The revascularization catheters are used for dilating stenotic vessels by mechanical dilation or micro-cutting, wherein a drug-coated stent or balloon can release drugs after dilation to prevent vascular restenosis. The thrombolysis catheter also belongs to a blood vessel recanalization catheter, and plays a role in recanalization by introducing thrombolysis medicines. The blood flow blocking catheter is an interventional catheter for blocking blood flow by means of balloon expansion and adherence.

The common interventional catheter is a balloon catheter, the basic structure of the common interventional catheter is a double-cavity structure, a central channel is a guide wire guide channel, the other channel at the tail part is a balloon filling channel which is communicated with a balloon, balloon expansion is realized by injecting gas or liquid, and the two cavities are isolated from each other. Balloons are classified as non-compliant, semi-compliant, and super-compliant.

The current various balloon catheters are designed for the purpose of recanalization of blood vessels or blocking of blood flow, and the application of chemical ablation by balloon administration is not considered. In certain diseases, blood vessels need to be destroyed for therapeutic purposes, such as severe greater saphenous vein varicose which requires removal or destruction of the greater saphenous vein, and KT syndrome which requires removal or destruction of the peripheral veins. The current primary methods are surgical resection, chemical disruption, or physical thermal ablation. The corresponding existing catheter approach for damaging blood vessels is divided into thermal ablation and drug injection through a catheter to damage the blood vessel walls, which are both inaccurate, and a large amount of normal blood is also damaged while the blood vessel walls are thermally or chemically damaged, so that medical potential hazards exist. In these diseases, only the vessel wall needs to be destroyed for therapeutic purposes.

Currently, no chemical ablation catheter is available to achieve precise destruction, such as precise anhydrous ethanol ablation of the vessel wall by a balloon catheter.

Disclosure of Invention

In order to overcome the defects of the prior art, the invention aims to provide the guide wire for the chemical ablation of the blood vessel, which can realize the accurate chemical destruction of the blood vessel wall, guide the double-layer balloon catheter, minimize the damage effect on normal blood and reduce the dosage of medicines.

In order to achieve the purpose, the invention adopts the technical scheme that:

a guide wire guide double-layer balloon catheter for chemical ablation of blood vessels comprises a catheter and a double-layer balloon arranged axially along the outer wall of the catheter, wherein the front end of the catheter is a guide wire traction head, and the rear end of the catheter is connected with a connector; the inner cavity of the catheter is divided into a guide wire guide channel, a balloon filling channel and a drug delivery channel which are independent from each other along the radial direction; the connector is provided with a first interface, a second interface and a third interface which are respectively communicated with the guide wire guide channel, the balloon filling channel and the drug delivery channel; the double-layer sacculus includes inlayer sacculus and outer sacculus of mutual cladding, forms outer cavity between the two after inlayer sacculus and the expansion of outer sacculus, forms interior cavity in the inlayer sacculus, and is isolated between two cavities, and outer sacculus is loose porous structure, and evenly it has the micropore to gather on the outer sacculus, interior cavity and pipe interior sacculus filling passageway intercommunication, outer cavity and pipe interconnection administration passageway intercommunication.

Further, micropores on the outer layer balloon are distributed at equal intervals.

Furthermore, the outer side of the catheter is provided with developing marks, and the two developing marks are positioned inside the double-layer balloon and close to the end part of the double-layer balloon.

Furthermore, the double-layer balloon is of a double-balloon structure arranged along the axial direction of the catheter, and the two balloons are mutually independent.

Further, the diameter of the conduit is 5Fr-10 Fr.

Further, the diameter of the double-layer balloon is 0.5cm-3.0cm, and the length of the double-layer balloon is 3cm-10 cm.

Furthermore, the volume of an outer cavity formed between the inner layer balloon and the outer layer balloon after the inner layer balloon and the outer layer balloon are expanded is 1.5-2.0 ml.

The invention has the following beneficial effects:

the guide wire guide double-layer balloon catheter for chemical ablation of blood vessels divides an inner cavity of the catheter into a guide wire guide channel, a balloon filling channel and a drug delivery channel which are independent from each other along the radial direction; one channel is used for guiding a guide wire, the other channel is used for filling a saccule, the third channel is communicated with an outer cavity formed between the inner saccule and the outer saccule after the inner saccule and the outer saccule are expanded, the outer saccule on the surface of the outer cavity is in a loose porous structure, micropores are uniformly and densely distributed on the outer saccule, after the saccule is expanded, a medicine is sent to the outer cavity through a medicine feeding channel, enters the surface of the saccule through the micropores and is contacted with the endothelium of a target blood vessel, and the wall of the; in the case of treating the same target blood vessel, it is possible to greatly reduce normal blood components and reduce the amount of the drug used, compared to conventional chemical destruction or thermal ablation.

When the sacculus is filled and is expanded back and the laminating of vascular wall, squeeze away blood, blood is few or basically not have blood between sacculus surface and the vascular wall, forms local high concentration environment after the medicine reaches the sacculus surface, and high concentration medicine is direct to contact and reach the destructive action with the vascular intima, will reduce the medicine quantity to the destructive action minimizing of normal blood simultaneously.

The connector sets up three independent interface respectively, and the pipe divides into three-dimensional branch form and leads to the sacculus surface, and each passageway does not influence each other, improves transport efficiency.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention

FIG. 2 is a schematic cross-sectional view of a catheter

FIG. 3 is a schematic view of a balloon structure

FIG. 4 is a partial enlarged view of the balloon

FIG. 5 is a schematic view of a double-balloon structure

In the figure: 1-catheter, 2-double-layer balloon, 3-connector, 4-first interface, 5-second interface, 6-third interface, 7-developing mark, 8-micropore, 9-inner-layer balloon, 10-outer-layer balloon, 11-guide wire guide channel, 12-balloon filling channel and 13-administration channel.

Detailed Description

The present invention will be described in further detail with reference to the following examples, which are not intended to limit the invention thereto.

As shown in figure 1, the guide wire guide double-layer balloon catheter for chemical ablation of blood vessels comprises a catheter 1 and a double-layer balloon 2 arranged along the axial direction of the outer wall of the catheter, wherein the balloon is coated outside the catheter 1 to form a closed structure, the balloon can expand after air or liquid is introduced into the catheter 1 to prop open a stenotic part of the blood vessels, the diameter of the catheter is 5Fr-10Fr, the diameter of the double-layer balloon 2 is 0.5cm-3.0cm, the length of the double-layer balloon is 3cm-10cm, and the balloon can be made of non-compliant, semi-compliant, compliant and super-compliant materials according to requirements.

As shown in fig. 2 and fig. 3, the front end of the catheter 1 is a guide wire traction head, the end part is small and gradually increases towards the back end, the back end of the catheter is connected with a connector 3, and the inner cavity of the catheter 1 is divided into a guide wire guide channel 11, a balloon filling channel 12 and a drug administration channel 13 which are mutually independent along the radial direction; the connector 3 is provided with a first interface 4, a second interface 5 and a third interface 6 which are respectively communicated with the guide wire guide channel 11, the balloon filling channel 12 and the administration channel 13; different materials are fed into the three channels through the structures, the second interface 5 is communicated with the guide wire guide channel 11 and keeps the same direction with the axial position of the catheter 1, the guide wire is prevented from being bent, and the guide wire guide channel 11 is used for the guide wire to pass through. Double-deck sacculus 2 is including the inlayer sacculus 9 and the outer sacculus 10 of mutual cladding, forms outer cavity between the two after inlayer sacculus 9 and the expansion of outer sacculus 10, forms interior cavity in the inlayer sacculus 9, it is isolated between two cavities, sacculus filling channel 12 and double-deck sacculus 2 inside cavity intercommunication, outer cavity and pipe 1 in-connection administration channel 13 intercommunication, send the sacculus into the focus position after, fill into air or liquid in the sacculus through sacculus filling channel 12 and fill up the expansion with the sacculus.

As shown in fig. 3 and 4, the outer balloon 10 is a loose porous structure, micropores 8 are uniformly and densely distributed on the outer balloon 10, and after the balloon is expanded, the micropores 8 are relaxed and opened to deliver the medicine to the surface of the balloon.

During the use, pack inlayer sacculus 9 earlier, then fill medicine to the passageway 13 of dosing through third interface 6 to certain pressure after, outer sacculus 10 surface micropore 8 is opened, and the medicine releases to the vascular wall, and the outer cavity volume that forms between the two after inlayer sacculus 9 and the expansion of outer sacculus 10 is 1.5-2.0ml, and the enough dose that holds needs has guaranteed the medicine supply volume.

As shown in fig. 3 and 4, a plurality of micropores 8 are distributed on the outer layer balloon 10 at equal intervals around the circumference, and the micropores 8 are easily stretched and opened after the balloon is expanded, so that the medicine can directly reach the surface of the balloon.

As shown in fig. 3 and 5, the developing marks 7 are arranged on the outer side of the catheter, the two developing marks 7 are positioned inside the double-layer balloon 2 and close to the end part of the double-layer balloon 2, and the balloon can conveniently track the position after entering the blood vessel.

As shown in fig. 5, the double-layer balloon 2 may also be a double-balloon structure disposed along the axial direction of the catheter 1, and the two balloons are independent from each other and respectively deliver drugs to the vascular lesion site.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solutions of the present invention and not for limiting the same, and although the present invention is described in detail with reference to the above embodiments, those of ordinary skill in the art should understand that: modifications and equivalents may be made to the embodiments of the invention without departing from the spirit and scope of the invention, which is to be covered by the claims.