阅读说明：本技术 防治羊尿石病的中药饲料添加剂及其制备方法和应用 (Traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis and preparation method and application thereof ) 是由 崔小七 陈长青 徐靖东 杨宏琰 丁佳丽 牛思原 梁桂霞 刘示范 陈盟 赵静 张旭 于 2019-10-21 设计创作，主要内容包括：本发明属于羊尿石病的防治技术领域,具体涉及一种防治羊尿石病的中药饲料添加剂及其制备方法和应用。该中药饲料添加剂由以下重量份的组分制成：车前子0.1～0.3份,滑石粉0.06～0.24份,白茅根0.05～0.26份,黄芪0.06～0.25份,麦芽0.09～0.35份,山药0.06～0.25份,甘草0.06～0.25份。以上诸药合用,起清热利水、利尿通淋、健脾开胃、行气消食之功效,在精料补充料中添加使用,大大降低了羊尿石症的发病率,且对尿石病患病羊有很好的治疗作用,且能够提高羊采食量,提高生产性能,效果显著,具有重要的市场价值和社会价值。(The invention belongs to the technical field of prevention and treatment of sheep urolithiasis, and particularly relates to a traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis and a preparation method and application thereof. The traditional Chinese medicine feed additive is prepared from the following components in parts by weight: 0.1-0.3 part of semen plantaginis, 0.06-0.24 part of talcum powder, 0.05-0.26 part of lalang grass rhizome, 0.06-0.25 part of astragalus membranaceus, 0.09-0.35 part of malt, 0.06-0.25 part of Chinese yam and 0.06-0.25 part of liquorice. The traditional Chinese medicine composition has the effects of clearing heat, promoting diuresis, treating stranguria, tonifying spleen, stimulating appetite, promoting qi circulation and helping digestion, is added into concentrate supplement materials, greatly reduces the incidence rate of the sheep urolithiasis, has a good treatment effect on sheep suffering from the urolithiasis, can improve the feed intake of the sheep, improves the production performance, has a remarkable effect, and has important market value and social value.)

1. The traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis is characterized by being prepared from the following components in parts by weight: 0.1-0.3 part of semen plantaginis, 0.06-0.24 part of talcum powder, 0.05-0.26 part of lalang grass rhizome, 0.06-0.25 part of astragalus membranaceus, 0.09-0.35 part of malt, 0.06-0.25 part of Chinese yam and 0.06-0.25 part of liquorice; the talcum powder is prepared by selecting, purifying, pulverizing and drying traditional Chinese medicine talcum.

2. The traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis as claimed in claim 1, which is prepared from the following components in parts by weight: 0.15-0.25 of plantain seed, 0.1-0.2 of talcum powder, 0.11-0.2 of cogongrass rhizome, 0.1-0.21 of astragalus membranaceus, 0.15-0.29 of malt, 0.11-0.18 of Chinese yam and 0.1-0.19 of liquorice.

3. The traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis as claimed in claim 1, which is prepared from the following components in parts by weight: 0.2 parts of plantain seeds, 0.12 parts of talcum powder, 0.13 parts of cogongrass rhizome, 0.125 parts of astragalus, 0.175 parts of malt, 0.125 parts of Chinese yam and 0.125 parts of liquorice.

4. The preparation method of the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis of any one of claims 1 ~ 3, which is characterized by comprising the following steps of uniformly mixing the components in parts by weight according to any one of claims 1 ~ 3, crushing or uniformly mixing the components after crushing, and obtaining powder material, namely the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis.

5. The use of the Chinese medicinal feed additive for preventing and treating sheep urolithiasis of any one of claims 1 ~ 3, wherein the Chinese medicinal feed additive for preventing and treating sheep urolithiasis of any one of claims 1 ~ 3 is added in an amount of 0.5% -1.5% of the daily sheep concentrate for stirring and mixing for 1 month to prevent sheep urolithiasis, or the Chinese medicinal feed additive for preventing and treating sheep urolithiasis of any one of claims 1 ~ 3 is added in an amount of 1% -3% of the daily sheep concentrate for stirring and mixing for 1 week to treat sheep urolithiasis.

Technical Field

The invention belongs to the technical field of prevention and treatment of sheep urolithiasis, and particularly relates to a traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis and a preparation method and application thereof.

Background

The sheep urolithiasis is a disease which is caused by that salt crystals mainly comprising calcium carbonate and phosphate are generated or reserved in renal pelvis, ureter and urethra to make sheep difficult to urinate and cause inflammation of urinary organs. Stud rams, castrated and barn-fed fattening lambs are prone to develop, and ewes are rare. The incidence of urolithiasis tends to increase year by year in the fattening period of mutton sheep under the barn feeding condition. Groaning and groping of the diseased sheep, head return to the abdomen, manifesting as urophobia and severe anuresis, which present a urination posture but do not urinate, and at this time, goat diet is reduced or abolished. The cesarean examination shows that the bladder has one time of edema, the blood vessels of the bladder wall are congested, the urine is dark and tawny, calculus blocks are easy to block at the neck of the bladder and the bending part of the penis, a large amount of fine sand-like sediments and large calculus are covered on the bottom wall of the bladder, and the calculus is white and irregular in shape.

When the feed is fed with concentrated feed with high protein and high phosphorus for a long time, the uric acid in blood is increased, the proportion of calcium and phosphorus is disordered, and then urinary calculus is induced. Toxic substances such as gossypol and the like cause sheep chronic poisoning, damage to kidney, organic matters generated by inflammation can disturb the balance of crystals and colloid in urine, deposition of unstable colloid, bacteria and pus and necrotic tissues caused by the bacteria become stone cores, and the occurrence rate of stones is increased. When the sheep lacks water, the urine is concentrated, the urine output is obviously reduced, and the crystallization deposition is caused to generate the calculus. In the case of urinary tract obstruction, the urine flow is slow and crystalline components in the urine tend to stay and settle in the urinary tract, resulting in the formation of stones. Changes in urine pH, resulting in acidic or alkaline urine, can increase the deposition of mineral salts. Generally, alkaline urine forms phosphate and carbonate stones, and acidic urine forms silicate stones. When vitamin B6 is deficient, endogenous oxalic acid in the body is increased, which is helpful for the formation of calculus. The prevention and treatment measures comprise that the calcium-phosphorus ratio in the daily ration is reduced to about 2:1, the occurrence of urolithiasis can be reduced, the water intake of sheep is increased, and the formation of urinary calculus is reduced. The mild sheep only take diuretic and antibiotic drugs, and the severe sheep only cuts the urethra to take out the calculus. Therefore, in the feeding management of sheep, attention must be paid to sheep urolithiasis, disease conditions must be found in time, and targeted measures are taken to prevent and treat the disease, otherwise serious loss is caused.

The invention patent with publication number CN106212902A discloses a ramie mixed pellet feed for preventing sheep urolithiasis, which is characterized in that Chinese herbal medicine additives with the effects of diuresis, spleen tonifying, stomach benefiting, diarrhea stopping and the like are added into a ramie mixed pellet feed, so that the feed intake is improved, the urolithiasis with sheep dysuria as a main symptom caused by serious imbalance of the calcium-phosphorus ratio of ramie is relieved, the growth performance of the mutton sheep and the addition amount of the ramie in daily ration of the mutton sheep are improved, and whether the ramie mixed pellet feed has the effects of preventing and treating sheep urolithiasis cannot be judged.

Disclosure of Invention

The invention aims to provide the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis and the preparation method and application thereof, the traditional Chinese medicine feed additive is added into concentrate supplement, the morbidity of the sheep urolithiasis is greatly reduced, the traditional Chinese medicine feed additive has a good treatment effect on sheep suffering from the urolithiasis, the feed intake of the sheep can be increased, the production performance is improved, the effect is obvious, and the market value and the social value are important.

In order to achieve the purpose, the invention adopts the following technical scheme:

the invention provides a traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis, which is prepared from the following components in parts by weight: 0.1-0.3 part of semen plantaginis, 0.06-0.24 part of talcum powder, 0.05-0.26 part of lalang grass rhizome, 0.06-0.25 part of astragalus membranaceus, 0.09-0.35 part of malt, 0.06-0.25 part of Chinese yam and 0.06-0.25 part of liquorice; the talcum powder is prepared by selecting, purifying, pulverizing and drying traditional Chinese medicine talcum.

Preferably, the feed additive is prepared from the following components in parts by weight: 0.15-0.25 of plantain seed, 0.1-0.2 of talcum powder, 0.11-0.2 of cogongrass rhizome, 0.1-0.21 of astragalus membranaceus, 0.15-0.29 of malt, 0.11-0.18 of Chinese yam and 0.1-0.19 of liquorice.

Preferably, the feed additive is prepared from the following components in parts by weight: 0.2 parts of plantain seeds, 0.12 parts of talcum powder, 0.13 parts of cogongrass rhizome, 0.125 parts of astragalus, 0.175 parts of malt, 0.125 parts of Chinese yam and 0.125 parts of liquorice.

The invention also provides a preparation method of the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis, which comprises the following steps: according to the components in parts by weight, the components are uniformly mixed and then crushed or are uniformly mixed after being crushed, and the obtained powder is the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis.

The invention also provides the application of the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis, wherein the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis is added according to 0.5-1.5% of the daily concentrate quality of sheep, and is stirred and mixed uniformly for 1 month to prevent the sheep urolithiasis; or the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis is added according to 1-3% of the daily concentrate quality of sheep, and is stirred and mixed evenly for 1 week continuously to treat the sheep urolithiasis.

Compared with the prior art, the invention has the beneficial effects that:

the invention relates to a traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis, which contains semen plantaginis, talcum powder and lalang grass rhizome, and is used for clearing heat, promoting diuresis and treating stranguria; radix astragali has effects of invigorating qi, consolidating superficial resistance, promoting urination and promoting granulation; the yam has the effects of tonifying spleen and nourishing stomach, and tonifying kidney and arresting seminal emission; the malt has the effects of promoting qi circulation, promoting digestion, invigorating spleen and stimulating appetite; the liquorice tonifies the spleen and the qi, clears away heat and toxic materials and harmonizes the other drugs. The traditional Chinese medicine composition has the effects of clearing heat, promoting diuresis, treating stranguria, tonifying spleen, stimulating appetite, promoting qi circulation and helping digestion, is added into concentrate supplement materials, greatly reduces the incidence rate of sheep urolithiasis, has a good treatment effect on sheep suffering from urolithiasis, can improve the feed intake of sheep, improves the production performance, has a remarkable effect, and has important market value and social value.

The traditional Chinese medicine components in the traditional Chinese medicine feed additive for preventing and treating sheep urolithiasis prepared by the invention are all from 117 traditional Chinese medicines in the feed raw material catalog announced by Ministry of agriculture of the people's republic of China, can be directly used as feed raw materials, do not need to be subjected to medicine approval, are easily available in raw materials, have no toxic or side effect, have the advantages of simple preparation and low price, and are easy to popularize.

Detailed Description

The following examples are intended to illustrate the invention, but are not intended to limit the scope of the invention. Unless otherwise specified, the technical means used in the examples are conventional means well known to those skilled in the art. The test methods in the following examples are conventional methods unless otherwise specified.