阅读说明：本技术 一种眼科晶状体超声成像方法及装置 (A kind of ophthalmic lens ultrasonic imaging method and device ) 是由 周盛 王晓春 杨军 计建军 王延群 于 2019-07-30 设计创作，主要内容包括：本发明提供一种眼科晶状体超声成像方法及装置,所述方法如下步骤：获取高位数格雷编码序列和低位数格雷编码序列；在高位数格雷编码序列和低位数格雷编码序列的激励下产生高位数编码超声波和低位数编码超声波发射至人体眼部组织；接收人体眼部组织反射回的与所述高位数编码超声波和低位数编码超声波相应的超声回波信号,并对所述超声回波信号进行放大以及模数转化处理获得数字回波信号；对所述数字回波信号进行数据处理获得图像数据信号；将所述图像数据信号成像,获得与所述高位数编码超声波和低位数编码超声波相应的超声灰阶图像。该眼科晶状体超声成像方法及装置,具有能够提高人体眼部晶状体的探测深度,从而实现晶状体的全景成像的优点。(The present invention provides a kind of ophthalmic lens ultrasonic imaging method and device, the method following steps: obtaining seniority top digit gray-code sequence and lower-order digit gray-code sequence；High-order number encoder ultrasonic wave is generated under the excitation of seniority top digit gray-code sequence and lower-order digit gray-code sequence and low level number encoder ultrasonic wave emits to human body ocular tissue；The ultrasound echo signal corresponding with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave that human body ocular tissue is reflected back is received, and the ultrasound echo signal is amplified and analog-to-digital conversion processing obtains digital echo signal；Data processing is carried out to the digital echo signal and obtains viewdata signal；Described image data-signal is imaged, ultrasound grayscale image corresponding with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave is obtained.The ophthalmic lens ultrasonic imaging method and device, having can be improved the lenticular investigation depth of human body eye, thus the advantages of realizing lenticular panoramic imagery.)

1. a kind of ophthalmic lens ultrasonic imaging method, characterized by the following steps:

Obtain seniority top digit gray-code sequence and lower-order digit gray-code sequence；

High-order number encoder ultrasonic wave and low is generated under the excitation of seniority top digit gray-code sequence and lower-order digit gray-code sequence Digit code ultrasonic wave emits to human body ocular tissue；

Receive that human body ocular tissue is reflected back with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave is corresponding surpasses Sound echo-signal, and the ultrasound echo signal is amplified and analog-to-digital conversion processing obtain digital echo signal；

Data processing is carried out to the digital echo signal and obtains viewdata signal；

Described image data-signal is imaged, is obtained corresponding with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave Ultrasound grayscale image.

2. ophthalmic lens ultrasonic imaging method according to claim 1, it is characterised in that: to the digital echo signal The step of carrying out data processing includes: to be decoded compaction algorithms to the digital echo signal to obtain decoded number and return Wave signal；Dynamic digital filtering processing is carried out to compressed digital echo signal is decoded, digital detection is handled, at logarithmic transformation Reason and median filter process are to obtain viewdata signal.

3. ophthalmic lens ultrasonic imaging method according to claim 1, it is characterised in that: the high position number encoder ultrasound Wave is generated by 16 gray-code sequence excitations；The low level number encoder ultrasonic wave is generated by 4 gray-code sequence excitations.

4. ophthalmic lens ultrasonic imaging method according to claim 1, it is characterised in that: surpass the high-order number encoder Successively compartment of terrain emits to human body ocular tissue to obtain the continuous ultrasound grayscale figure of multiframe for sound wave and low level number encoder ultrasonic wave Picture.

5. ophthalmic lens ultrasonic imaging method according to claim 4, it is characterised in that: to the ultrasound grayscale of consecutive frame Image is weighted the ultrasound grayscale image for subtracting each other processing to obtain lens interior.

6. ophthalmic lens ultrasonic imaging method according to claim 5, it is characterised in that: obtain the lens interior Ultrasound grayscale image pixel quantity and each pixel grayscale value, and calculate the average gray of all pixels point Value.

7. ophthalmic lens ultrasonic imaging method according to claim 1, it is characterised in that: to the lens interior Ultrasound grayscale image carries out binary conversion treatment, distinguishes the high echogenic area domain and low echo area domain in image.

8. ophthalmic lens ultrasonic imaging method according to claim 1, it is characterised in that: to the lens interior Ultrasound grayscale image carries out the differential process of x-axis direction and the gray value on y-axis direction respectively, and draws out matched curve figure, Realize the texture analysis of image.

9. a kind of ophthalmic lens panoramic imaging device, it is characterised in that: may be programmed including programmable logic device and with described The ultrasonic transducer and signal processing module of logical device electrical connection；

The programmable logic device obtains seniority top digit gray-code sequence and lower-order digit gray-code sequence, by the seniority top digit Gray-code sequence and lower-order digit gray-code sequence are exported to the ultrasonic transducer, motivate ultrasonic transducer to generate high Digit code ultrasonic wave and low level number encoder ultrasonic wave emit to human body ocular tissue；

What the ultrasonic transducer reception human body ocular tissue was reflected back compiles with the high-order number encoder ultrasonic wave and lower-order digit The code corresponding ultrasound echo signal of ultrasonic wave, is sent to the signal processing module；

The signal processing module is received and is amplified to the ultrasound echo signal and analog-to-digital conversion process, is obtained number and is returned Wave signal, and it is sent to the programmable logic device；

The programmable logic device carries out data processing to the digital echo signal and obtains viewdata signal, and will be described Viewdata signal is transmitted to host computer imaging, obtains corresponding to the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave Ultrasound grayscale image.

10. ophthalmic lens panoramic imaging device according to claim 9, it is characterised in that: the programmable logic device Part is provided with sequentially connected decoding tool of compression, dynamic digital filtering device, digital detector, logarithmic converter and median filtering Device；

The decoding tool of compression is decoded compaction algorithms to the digital echo signal to obtain decoded digital echo Signal；

The dynamic digital filtering device carries out dynamic digital filtering processing to compressed digital echo signal is decoded；

The digital detector carries out digital detection processing to the filtered digital echo signal of the dynamic digital filtering device；

The logarithmic converter carries out logarithmic transformation processing to the digital detector detection treated digital echo signal；

The median filter carries out median filter process to the logarithmic converter treated digital echo signal and obtains institute State viewdata signal.

Technical field

The present invention relates to ophthalmology technical field of imaging, more particularly to a kind of ophthalmic lens ultrasonic imaging method and dress It sets.

Background technique

Cataract is the primary factor of China's mid-aged population blinding, if being capable of its type of accurate judgement and durometer level Not, there is important clinical meaning for the success rate of the treatment of cataract such as ultrasonic emulsification intraocular lens implantation.And it is white interior The judgement of the hardness level and type of barrier then depends on the judgement of human body eye crystalline lens character, therefore, human body eye crystalline lens Detection it is particularly important.Generally observe lenticular form on the clinical ophthalmology of early stage using optical detection apparatus, but due to Optical check is easy to be influenced by refracting media nubecula degree and pupil size, and the crystallin qualitative change of cataract patient Property and cause the transparency decline can interfere even block light normal propagation, therefore, optical detection can not detect eye well Portion organizes overall picture, and during medical development, ultrasound detection is gradually instead of the optical detection of early stage.

Currently, the ultrasonic detection equipment for clinical ophthalmology is mainly ultrasound biomicroscopy UBM, pass through single pulse excitation Signal excitation ultrasonic transducer issues ultrasonic wave and emits to human body ocular tissue, obtains the ultrasound that human body ocular tissue is reflected back and returns Wave simultaneously forms ultrasound image to carry out the analysis and judgement of eye crystalline lens character.But due to motivating ultrasound by single pulse signal The depth for the human body ocular tissue that the detection method of wave can detect is shallower, cannot achieve lenticular panoramic imagery.

Summary of the invention

To overcome the problems in correlation technique, the embodiment of the invention provides a kind of ophthalmic lens ultrasonic imaging sides Method has the advantages that can be improved the lenticular investigation depth of human body eye to realize lenticular panoramic imagery.

A kind of ophthalmic lens ultrasonic imaging method, includes the following steps:

Obtain seniority top digit gray-code sequence and lower-order digit gray-code sequence；

High-order number encoder ultrasonic wave is generated under the excitation of seniority top digit gray-code sequence and lower-order digit gray-code sequence Emit with low level number encoder ultrasonic wave to human body ocular tissue；

Reception human body ocular tissue is reflected back corresponding to the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave Ultrasound echo signal, and the ultrasound echo signal is amplified and analog-to-digital conversion processing obtain digital echo signal；

Data processing is carried out to the digital echo signal and obtains viewdata signal；

Described image data-signal is imaged, is obtained and the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave phase The ultrasound grayscale image answered.

Ophthalmic lens ultrasonic imaging method described in the present embodiment joins by using high-order number encoder and low level number encoder Synthesized image can realize the detection of more depth to human body eye crystalline lens, to realize lenticular panoramic imagery.

Further, the step of carrying out data processing to the digital echo signal includes: to the digital echo signal Compaction algorithms are decoded to obtain decoded digital echo signal；Dynamic is carried out to compressed digital echo signal is decoded Digital filtering processing, digital detection processing, logarithmic transformation processing and median filter process are to obtain viewdata signal.

Further, the high-order number encoder ultrasonic wave is generated by 16 gray-code sequence excitations；The lower-order digit is compiled Code ultrasonic wave is generated by 4 gray-code sequence excitations.

Further, by the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave, successively compartment of terrain emits to human body Ocular tissue is to obtain the continuous ultrasound grayscale image of multiframe.

Further, obtain the ultrasound grayscale image of the lens interior pixel quantity and each pixel Grayscale value, and the average gray value of all pixels point is calculated, lenticular muddy degree is judged according to the average gray value.

Further, binary conversion treatment is carried out to the ultrasound grayscale image of the lens interior, distinguished in image High echogenic area domain and low echo area domain, are judged with the type to cataract.

Further, the ash in x-axis direction and y-axis direction is carried out respectively to the ultrasound grayscale image of the lens interior The differential process of angle value, and matched curve figure is drawn out, realize the texture analysis of image.

The embodiment of the invention also provides a kind of ophthalmic lens panoramic imaging device, including programmable logic device and with The ultrasonic transducer and signal processing module of the programmable logic device electrical connection；

The programmable logic device obtains seniority top digit gray-code sequence and lower-order digit gray-code sequence, by the height Digit gray-code sequence and lower-order digit gray-code sequence are exported to the ultrasonic transducer, and ultrasonic transducer is motivated to produce Raw high position number encoder ultrasonic wave and low level number encoder ultrasonic wave emit to human body ocular tissue；

The ultrasonic transducer receive that human body ocular tissue is reflected back with the high-order number encoder ultrasonic wave and low level The corresponding ultrasound echo signal of number encoder ultrasonic wave, is sent to the signal processing module；

The signal processing module is received and is amplified to the ultrasound echo signal and analog-to-digital conversion process, obtains number Word echo-signal, and it is sent to the programmable logic device；

The programmable logic device carries out data processing to the digital echo signal and obtains viewdata signal, and will Described image data signal transmission to host computer is imaged, and obtains and the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave Corresponding ultrasound grayscale image.

Further, the programmable logic device is provided with sequentially connected decoding tool of compression, dynamic digital filtering Device, digital detector, logarithmic converter and median filter；

The decoding tool of compression is decoded compaction algorithms to the digital echo signal to obtain decoded number Echo-signal；

The dynamic digital filtering device carries out dynamic digital filtering processing to compressed digital echo signal is decoded；

The digital detector carries out at digital detection the filtered digital echo signal of the dynamic digital filtering device Reason；

The logarithmic converter carries out at logarithmic transformation the digital detector detection treated digital echo signal Reason；

The median filter carries out median filter process to the logarithmic converter treated digital echo signal.

Ophthalmic lens panoramic imaging device described in the embodiment of the present invention can be realized the lenticular depth of eye and visit It surveys, obtains lenticular panoramic imagery, in order to which doctor is to the crystalline lens hardness level of cataract patient and cataract type Judgement.

It should be understood that above general description and following detailed description be only it is exemplary and explanatory, not It can the limitation present invention.

In order to better understand and implement, the invention will now be described in detail with reference to the accompanying drawings.

Detailed description of the invention

Fig. 1 is the flow chart of ophthalmic lens ultrasonic imaging method described in the embodiment of the present invention；

Fig. 2 is the flow chart of data processing figure of digital echo signal described in the embodiment of the present invention；

Fig. 3 is the structural schematic diagram of ophthalmic lens supersonic imaging device described in the embodiment of the present invention.

Specific embodiment

Example embodiments are described in detail here, and the example is illustrated in the accompanying drawings.Following description is related to When attached drawing, unless otherwise indicated, the same numbers in different drawings indicate the same or similar elements.Following exemplary embodiment Described in embodiment do not represent all embodiments consistented with the present invention.On the contrary, they be only with it is such as appended The example of device and method being described in detail in claims, some aspects of the invention are consistent.

It is only to be not intended to limit the invention merely for for the purpose of describing particular embodiments in terminology used in the present invention. It is also intended in the present invention and the "an" of singular used in the attached claims, " described " and "the" including majority Form, unless the context clearly indicates other meaning.It is also understood that term "and/or" used herein refers to and wraps It may be combined containing one or more associated any or all of project listed.

The running environment of this ophthalmic lens ultrasonic imaging method includes programmable logic device and patrols with described may be programmed Collect ultrasonic transducer, signal processing module and the host computer of device electrical connection.

Referring to Fig. 1, its flow chart for ophthalmic lens ultrasonic imaging method described in the embodiment of the present invention.

In the present embodiment, the ophthalmic lens ultrasonic imaging method includes the following steps:

S1: seniority top digit gray-code sequence and lower-order digit gray-code sequence are obtained；

S2: high-order number encoder ultrasound is generated under the excitation of seniority top digit gray-code sequence and lower-order digit gray-code sequence Wave and low level number encoder ultrasonic wave emit to human body ocular tissue；

S3: receive that human body ocular tissue is reflected back with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave phase The ultrasound echo signal answered, and the ultrasound echo signal is amplified and analog-to-digital conversion processing obtain digital echo letter Number；

S4: data processing is carried out to the digital echo signal and obtains viewdata signal；

S5: described image data-signal is imaged, and is obtained and the high-order number encoder ultrasonic wave and low level number encoder ultrasound The corresponding ultrasound grayscale image of wave.

Gray code is illustrated below: in the coding of one group of number, if the adjacent code of any two only has one Binary number is different, then claim it is this be encoded to Gray code (Gray Code), additionally, due between maximum number and minimum number also only one Digit is different, i.e., " joins end to end ", therefore also known as cyclic code or reflected code.Gray code belongs to Reliability codes, is a kind of mistake The coding mode accidentally minimized.Because although natural binary code directly can be converted into analog signal by D/A converter, But in certain situations, for example, from metric 3 be converted to 4 when binary code each will become, digital circuit can be made to generate Very big peak current pulse.And Gray code is then without this disadvantage, when adjacent interdigit is converted, only one generation becomes for it Change, logic obscures when greatly reducing by a state to next state.Due to two adjacent code characters of this coding Between an only difference, thus in corner displacement amount-digital quantity conversion for direction, when the corner displacement in direction Minor change occurs for amount, and when may cause digital quantity and changing, Gray code only changes one, same with other codings in this way When a possibility that changing two or the case where multidigit compared to more reliable, error can be reduced.

In step s 2, the high-order number encoder ultrasonic wave is generated by 16 gray-code sequence excitations；The lower-order digit It encodes ultrasonic wave to be generated by 4 gray-code sequence excitations, and the high-order number encoder ultrasonic wave and low level number encoder is ultrasonic Successively compartment of terrain emits to human body ocular tissue to obtain multiframe continuous ultrasound grayscale image wave.In the specific implementation process, First emit the seniority top digit ultrasonic wave that 16 gray-code sequence excitations generate, obtains a frame image；Then emit 4 Grays again to compile The lower-order digit ultrasonic wave that code train excitation generates, obtains the second frame image, the transmitting high position number encoder ultrasound being successively spaced in this way Wave and low level number encoder ultrasonic wave are obtained with corresponding multiframe continuous ultrasound gray scale image.

The ophthalmic lens ultrasonic imaging method of the invention single pulse excitation traditional using digital coding motivation substitution, makes System voice output parameter is under the premise of meeting coherent detection standard, while keeping emitting voltage and image resolution ratio, improves The average emitted power of ultrasonic wave realizes effective promotion of supersonic sounding depth, obtains the panoramic imagery of ophthalmic lens.

Referring to Fig. 2, its flow chart of data processing figure for digital echo signal described in the embodiment of the present invention.

In step s 4, the step of carrying out data processing to the digital echo signal includes: S41: being returned to the number Wave signal is decoded compaction algorithms to obtain decoded digital echo signal；S42: believe compressed digital echo is decoded Number carry out dynamic digital filtering processing；S43: digital detection processing is carried out to the digital echo signal after dynamic digital filtering； S44: logarithmic transformation processing is carried out to digital detection treated digital echo signal；S45: to logarithmic transformation treated number Echo-signal carries out median filter process, obtains viewdata signal.

Described image data-signal is finally converted into the identifiable data flow of USB, host computer is transmitted to by USB interface Imaging obtains ultrasound grayscale image corresponding with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave.

Ophthalmic lens ultrasonic imaging method described in the present embodiment joins by using high-order number encoder and low level number encoder Synthesized image can realize the detection of more depth to human body eye crystalline lens, to realize lenticular panoramic imagery.

Further, also the ultrasound grayscale image of consecutive frame is weighted and subtracts each other processing, with obtain small signal message compared with The ultrasound grayscale image of the lens interior of horn of plenty.Wherein, small signal refers to the human body echo that ultrasonic transducer receives The method of weak signal in information, height digit code excitation ultrasonic imaging can make the small signal in ultrasound grayscale image Information is remarkably reinforced；Corresponding with small signal is big signal, is referred in human body echo information that ultrasonic transducer receives Strong signal.

Since the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave are that successively compartment of terrain emits to human body eye Tissue, then correspondingly, the ultrasonic transducer, which can be successively spaced, to be received and the high-order number encoder ultrasonic wave and low level Number encoder ultrasonic wave corresponding ultrasound echo signal obtains multiframe continuous ultrasound grayscale image when imaging, therein adjacent Frame image is then corresponding with high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave respectively.By two width ultrasound grayscales of consecutive frame Image, which is weighted, subtracts each other processing, to remove the strong reflections such as boundary ultrasound information, the small letter of cataract part in prominent crystalline lens Number information, eliminates the interference of big signal, and the ultrasound grayscale image of lens interior can then be obtained by finally carrying out regional choice.

Since the average gray value of ultrasonic imaging is one of the judgment criteria of cataract muddiness degree, it is worth bigger, muddy journey It spends more serious.It, can also ultrasound grayscale figure to the lens interior for the lenticular turbidity for judging cataract patient The average gray value of the pixel of picture is calculated, if average gray value is higher, the turbidity of cataractous lens is got over The eyesight of height, patient is poorer.Its calculation are as follows: obtain the pixel quantity of the ultrasound grayscale image of the lens interior with And the grayscale value of each pixel；Calculate the average gray value of all pixels point；Judged according to the average gray value crystalline The muddy degree of body.

The property of cataract can be divided into property under cortex, nuclearity and Lens capsular.For convenient for sentencing to cataract property It is disconnected, it also needs to carry out binary conversion treatment to the ultrasound grayscale image of the lens interior, to obtain high echogenic area and low echo area Location map, that is, distinguish the high echogenic area domain and low echo area domain in image, and according to the distributing position of high echogenic area The property of qualitative analysis cataract is judged with the type to cataract.

For the texture analysis for realizing image, also need to carry out x-axis side respectively to the ultrasound grayscale image of the lens interior To the differential process with the gray value on y-axis direction, and matched curve figure is drawn out, to obtain grayscale numerical value in both direction The slope of curve variation Two dimensional Distribution, to judge cataract hardness rank.Grayscale value slope variation is relatively gentle, determines hard It spends lower；Slope appearance is obviously mutated, and determines that hardness is higher.

Ophthalmic lens ultrasonic imaging method described in the present embodiment joins by using high-order number encoder and low level number encoder Synthesized image can realize the detection of more depth, not only to improve the average emitted power of ultrasonic wave to human body eye crystalline lens It can detect on lenticular along part, moreover it is possible to lenticular trailing edge portion is detected, to realize the lenticular entirety of eye Detection, obtains lenticular panoramic imagery.Meanwhile it being easy to implement corneal thickness, anterior chamber depth, crystal thickness, signal amplitude and declining Subtract, frequency shift (FS), the parameters such as average brightness automatic measurement；Furthermore it is also possible to by Texture Analysis of B Scan Image algorithm with reality The automatic detection and hardness classification of existing Lenticular cataract type.

The present invention also provides a kind of ophthalmic lens supersonic imaging device, specific structure is referring to Fig. 3, it is this The structural schematic diagram of the ophthalmic lens supersonic imaging device is implemented in invention.

The ophthalmic lens supersonic imaging device include programmable logic device 10 and with the programmable logic device The ultrasonic transducer 20 and signal processing module 30 of 10 electrical connections.For realize ultrasound grayscale image imaging, by the ophthalmology Crystalline lens supersonic imaging device is connect by data line with host computer 40, and host computer 40 is equipped with image processing software, in image It is observed that obtained ultrasound grayscale image in processing software, and ultrasound grayscale image can be carried out by image processing software Analysis and processing.It is shown it should be noted that host computer 40 can be laptop, desktop computer, and other have Screen, memory, processor electronic equipment.

The programmable logic device 10 obtains seniority top digit gray-code sequence and lower-order digit gray-code sequence, will be described Seniority top digit gray-code sequence and lower-order digit gray-code sequence are exported to the ultrasonic transducer 20.Specifically, Gray compiles Code sequence can write in advance in the memory of programmable logic device 10, when programmable logic device 10 receives host computer 40 Transmitting trigger signal after, pass through specific I/O interface exports coding pulse signal to ultrasonic transducer 20 motivate ultrasonic waves It can the generation coding ultrasonic wave transmitting of device 20.

The ultrasonic transducer 20 under the excitation of seniority top digit gray-code sequence and lower-order digit gray-code sequence according to The high-order number encoder ultrasonic wave of secondary generation and low level number encoder ultrasonic wave emit to human body ocular tissue, wherein the seniority top digit encodes Ultrasonic wave is generated by 16 gray-code sequence excitations；The low level number encoder ultrasonic wave is produced by 4 gray-code sequence excitations It is raw.

When human body ocular tissue is by ultrasonic reflections, the ultrasonic transducer 20 receives human body ocular tissue and is reflected back Ultrasound echo signal corresponding with the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave, be sent at the signal Manage module 30.Specifically, the ultrasonic transducer 20 be single crystal oscillator broadband ultrasonic transducer, centre frequency 50Hz, Bandwidth is 70%.

The signal output end of the programmable logic device 10 is also connected with very short reach transmitting module, very short reach Transmitting module generates high-voltage pulse under the Gray code pulse signal effect and exports to the ultrasonic transducer 20.It is described Ultrasonic transducer 20 receives the high-voltage pulse, and coding ultrasonic wave is generated under the excitation of the high-voltage pulse and is emitted to human body Ocular tissue, i.e., successively interval generates high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave emits to human body ocular tissue.

The signal processing module 30 is received and is amplified to the ultrasound echo signal and analog-to-digital conversion process, is obtained Digital echo signal, and it is sent to the programmable logic device 10.

In the present embodiment, the signal processing module 30 includes being sequentially connected to 20 signal of the ultrasonic transducer output The preamble reception amplifying circuit and high-speed data analog-to-digital conversion module at end.The preamble reception amplifying circuit receives described encode back Wave signal, and coded echo signal is amplified, output to the high-speed data analog-to-digital conversion module.The high-speed data mould Amplified coded echo signal is carried out analog-to-digital conversion and obtains digital coding echo-signal by number conversion modules, be sent to it is described can In the memory of programmed logic device 10.Wherein, the sample frequency of high-speed data analog-to-digital conversion module be 240MHz, 14.

Specifically, the overall gain of the pre-amplification circuit is 80dB, adjustable gain range is 40dB.The preposition amplification Circuit includes the operational amplifier chip of one group of low noise, high speed, the negative-feedback mode powered using single supply, in conjunction with passive filter Wave network, realize matching with ultrasonic transducer with couple, obtain better signal processing efficiency.It is to ultrasonic wave transducer The ultrasound echo signal that device receives carries out primary amplification, and gain amplifier can pass through host computer 40 between 15~20dB Realize the gain adjustment of pre-amplification circuit, adjustable gain range is 40dB, to obtain better image data.

The high-speed data analog-to-digital conversion module realizes analog signal to number using high speed analog-to-digital converter chip as core The transformation of signal, sample frequency 240MHz, digit 14bits.

The programmable logic device 10 carries out data processing to the digital echo signal and obtains and seniority top digit volume Code ultrasonic wave and the corresponding viewdata signal of low level number encoder ultrasonic wave, and described image data-signal is converted to USB can The data stream transmitting of identification to the host computer 40 is imaged, and obtains and the high-order number encoder ultrasonic wave and low level number encoder ultrasound The continuous ultrasound grayscale image of the corresponding multiframe of wave, to realize the panoramic imagery of lens interior.

The programmable logic device 10 be internally provided with decoding tool of compression interconnected, dynamic digital filtering device, Digital detector, logarithmic converter and median filter；Wherein, the process of data processing is by decoding tool of compression, dynamic digital Filter, digital detector, logarithmic converter and median filter are sequentially completed.Data are carried out to the digital echo signal Specific step includes: to be decoded compaction algorithms to the digital echo signal by decoding tool of compression to obtain in processing Decoded digital echo signal；Dynamic digital is carried out to compressed digital echo signal is decoded by dynamic digital filtering device Filtering processing；Digital detection processing is carried out to the digital echo signal after dynamic digital filtering by digital detector；By right A/D converter carries out logarithmic transformation processing to digital detection treated digital echo signal；Finally by median filter to right Transformation of variables treated digital echo signal carries out median filter process, obtains viewdata signal.

Due to normal eye's crystalline lens be it is colorless and transparent, shown as in ultrasonic imaging only before and after crystalline lens boundary have Apparent echo information, and lens interior is without any signal.And the crystalline lens of cataract patient can gradually become muddy by transparent It is turbid, and as the intensification of cataract degree, internal can be more and more muddy, translucency slowly declines, until blindness, and get over Ultrasonic wave can be emitted come more muddy crystalline lens, i.e. different degrees of return occurs in the lens interior of cataract patient Wave information, echo information are abundanter, then it represents that lenticular turbidity is higher, and the decaying of ultrasonic energy is also more serious.

Subtract each other processing in addition, being also weighted by ultrasound grayscale image of the host computer 40 to consecutive frame, to obtain small letter The ultrasound grayscale image of number information lens interior more abundant.Wherein, small signal refers to what ultrasonic transducer received The method of weak signal in human body echo information, height digit code excitation ultrasonic imaging can make in ultrasound grayscale image Small signal message be remarkably reinforced；Big signal refers to the strong signal in the human body echo information that ultrasonic transducer receives.

Since the high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave are that successively compartment of terrain emits to human body eye Tissue, then correspondingly, the ultrasonic transducer, which can be successively spaced, to be received and the high-order number encoder ultrasonic wave and low level Number encoder ultrasonic wave corresponding ultrasound echo signal obtains the continuous ultrasound grayscale image of multiframe, and consecutive frame figure when imaging As then corresponding with high-order number encoder ultrasonic wave and low level number encoder ultrasonic wave respectively.By two width ultrasound grayscale images of consecutive frame It is weighted and subtracts each other the strong reflections ultrasound informations such as processing removal boundary, the small signal message of cataract part in prominent crystalline lens, The interference of big signal is eliminated, the ultrasound grayscale image of lens interior can then be obtained by finally carrying out regional choice, in order to rear Continuous computer assisted image processing.

Since the average gray value of ultrasonic imaging is one of the judgment criteria of cataract muddiness degree, it is worth bigger, muddy journey It spends more serious.It, can also be by host computer 40 to the lens interior for the lenticular turbidity for judging cataract patient The average gray value of pixel of ultrasound grayscale image calculated, if average gray value is higher, cataractous lens Turbidity it is higher, the eyesight of patient is poorer.Specifically implementation steps are as follows: obtain the ultrasound grayscale figure of the lens interior The grayscale value of the pixel quantity of picture and each pixel；Calculate the average gray value of all pixels point；According to described flat Equal gray value judges lenticular muddy degree.

The property of cataract can be divided into property under cortex, nuclearity and Lens capsular.For convenient for sentencing to cataract property It is disconnected, binary conversion treatment is also carried out by ultrasound grayscale image of the host computer 40 to the lens interior, to obtain high echogenic area With the location map of low echo area, that is, high echogenic area domain and low echo area domain in image are distinguished, and according to high echogenic area Distributing position qualitative analysis cataract property.

Texture analysis refers to the crystalline lens ultrasound image to cataract patient, removes the information progress of inside behind the interface of front and back Analysis and processing.For the texture analysis for realizing image, also pass through host computer 40 to the ultrasound grayscale image of the lens interior The differential process of x-axis direction and the gray value on y-axis direction is carried out respectively, and draws out matched curve figure, to obtain two The Two dimensional Distribution of the slope of curve variation of grayscale numerical value on direction, to judge cataract hardness rank.Grayscale value slope variation phase To gentle, determine that hardness is lower；Slope appearance is obviously mutated, and determines that hardness is higher.

Furthermore it is also possible to judge that lenticular cataract is muddy along the difference of the echo information on boundary using crystalline lens front and back Turbid degree and hardness.Since normal human's crystals are uniform dielectric, ultrasonic echo information will not be generated.When there is cataract When disease, it just will appear different degrees of ultrasound echo signal, with the raising of lesion degree, information also can gradually be enriched, This also leads to echo information of the crystal front and back along boundary and significant difference occurs in terms of spectrum distribution and amplitude distribution.Therefore, Automatic detection can be realized by interface boundary before and after the crystalline lens ultrasound two dimensional image to cataract patient, and combine energy converter Bandwidth distribution, calculate boundary echo information frequency shift (FS) and amplitude attenuation mean value and variance yields, with the class to cataract Type is judged.

Ophthalmic lens supersonic imaging device described in the present embodiment emits high-order number encoder ultrasonic wave by being successively spaced With low level number encoder ultrasonic wave, the energy of ultrasonic signal is improved to improve the average emitted power of ultrasonic wave, it can be to people Body eye crystalline lens realizes the detection of more depth, and can significantly improve the acquisition of tiny signal in ultrasound echo signal, rich The diagnostic message of rich cataractous lens.Meanwhile to the seniority top digit coded echo signal and lower-order digit coded echo signal of acquisition Related computing is carried out finally to divide ultrasound grayscale image to obtain the panorama ultrasound grayscale image of lens interior Analysis processing.Obtain panorama ultrasound grayscale image be advantageously implemented corneal thickness, anterior chamber depth, crystal thickness, signal amplitude decaying, The automatic measurement of the parameters such as frequency shift (FS), average brightness；In addition, can also be realized by Texture Analysis of B Scan Image algorithm crystalline The automatic detection and hardness classification of body cataract type.

The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention Range.