阅读说明：本技术 一种用抗菌防污微胶囊整理棉布绷带的方法 (A method of cotton bandage is arranged with the antifouling microcapsules of antibacterial ) 是由 朱清 于 2019-08-09 设计创作，主要内容包括：本发明公开了一种用抗菌防污微胶囊整理棉布绷带的方法,将低表面能的整理剂、无水乙醇和去离子水充分混合,滴加冰乙酸水解后,将碱减量处理的棉布绷带浸入其中,水浴振荡得氟硅烷处理的棉布绷带；向芦荟苷-氧化石墨烯-甜菜碱复合凝胶中加阿拉伯树胶粉溶液搅拌溶解,滴加水溶性壳聚糖溶液,恒温水浴磁力搅拌,加同温同体积的蒸馏水混匀,恒温搅拌复凝聚,降温,添加戊二醛交联固化反应,静置过滤、真空冷冻干燥得抗菌防污微胶囊；将所得抗菌防污微胶囊加入水中,在水浴中磁力搅拌,加入渗透剂,得抗菌防污整理液,将所得氟硅烷处理的棉布绷带在其中浸渍,轧压,二次浸渍,二次轧压,预烘,烘焙,皂洗、水洗、自然干燥得抗菌防污整理的棉布绷带。(The invention discloses a kind of methods for arranging cotton bandage with the antifouling microcapsules of antibacterial, the finishing agent, dehydrated alcohol and deionized water of low-surface-energy are sufficiently mixed, be added dropwise glacial acetic acid hydrolysis after, the cotton bandage of alkali decrement treatment is immersed, water-bath vibrate silicon fluoride processing cotton bandage；Add gum arabic powder solution stirring and dissolving into barbaloin-graphene oxide-glycine betaine plural gel, water soluble chitosan solution is added dropwise, water bath with thermostatic control magnetic agitation, the distilled water of equality of temperature same volume is added to mix, the multiple cohesion of constant temperature stirring, glutaraldehyde cross-linking curing reaction is added in cooling, stands filtering, vacuum freeze drying obtains the antifouling microcapsules of antibacterial；The antifouling microcapsules of gained antibacterial are added to the water, magnetic agitation in a water bath, bleeding agent is added, obtains antibacterial antifouling finishing liquid, the cotton bandage that gained silicon fluoride is handled is impregnated wherein, roll compacting, double-steeping, secondary roll compacting, preliminary drying, bake, soap, wash, spontaneously drying antibacterial soil resistant finish cotton bandage.)

1. a kind of method for arranging cotton bandage with the antifouling microcapsules of antibacterial, which is characterized in that include the following steps, following raw materials By weight:

The silicon fluoride treatment process of cotton bandage:

By finishing agent 1H, 1H, 2H, 2H- perfluoro capryl triethoxysilane, the 99-198 parts of dehydrated alcohols of 1-2 parts of low-surface-energies It is sufficiently mixed with 100-200 parts of deionized waters, it is 3 that glacial acetic acid, which is added dropwise, and adjusts pH, after hydrolyzing 30-40min, by bath raio 1:40 by alkali The cotton bandage of decrement treatment is immersed, and vibrates 1-2h in 90-95 DEG C of water-bath, take out silicon fluoride processing cotton it is taut Band；

(2) preparation method of the antifouling microcapsules of antibacterial:

3.3-6.7 parts of gum arabic powder solution, In are added into 1-2 parts of barbaloin-graphene oxide-glycine betaine plural gels 0.67-1.3 parts of water soluble chitosan solution, the magnetic agitation in 40-45 DEG C of water bath with thermostatic control is added dropwise in stirring and dissolving at 40-45 DEG C 10-15min, the distilled water that equality of temperature same volume is added mix, and adjusting pH is 4-5, and constant temperature stirs multiple cohesion, and taking-up is cooled to 0-5 DEG C, 0.1-0.2 parts of glutaraldehyde cross-linking curing reaction 30-40min are added, it is antifouling micro- that standing filters, vacuum freeze drying obtains antibacterial Capsule；

(3) padding process of cotton bandage:

The gained antifouling microcapsules 1:5 of antibacterial in (2) is added to the water, 2-3 parts of infiltrations are added in the magnetic agitation in 40-50 DEG C of water-bath Saturating agent obtains antibacterial antifouling finishing liquid, by the cotton bandage of gained silicon fluoride processing in (1) by bath raio 1:30 in antibacterial soil resistant finish 30-40min, roll compacting, double-steeping 30-40min, secondary roll compacting, the preliminary drying 10-20min at 40-50 DEG C, in 80- are impregnated in liquid Bake 5-10min at 100 DEG C, soap, wash, spontaneously drying antibacterial soil resistant finish cotton bandage.

2. a kind of method for arranging cotton bandage with the antifouling microcapsules of antibacterial according to claim 1, which is characterized in that step Suddenly in (1) cotton bandage alkali decrement treatment technique: by sodium hydroxide solution heating water bath that mass concentration is 25g/L to 75- 90 DEG C, pretreated cotton bandage is immersed by bath raio 1:30-40, the cetyl three of 1-2 parts of promotor 2g/L is added Ammonio methacrylate, alkali decrement treatment 1-2h, washing to neutrality, drying obtains the cotton of alkali decrement treatment in 40-50 DEG C of baking oven Bandage；

The preprocess method of cotton bandage: being cleaned by ultrasonic 10-15min for cotton bandage in acetone, takes out, in deionized water After being cleaned by ultrasonic 5-10min, pretreated cotton bandage is dried to obtain in 55-60 DEG C of baking oven.

3. a kind of method for arranging cotton bandage with the antifouling microcapsules of antibacterial according to claim 1, which is characterized in that step Suddenly barbaloin-graphene oxide-glycine betaine plural gel preparation in (2): 3-6 parts of carbomers are swollen in deionized water, 2-4 parts of barbaloins and 2-4 parts of graphene oxides-glycine betaine composite material is added, ultrasound mixes, and three second of 1-2 part is added dropwise under stirring Hydramine obtains barbaloin-graphene oxide-glycine betaine plural gel；

The synthesis of graphene oxide-glycine betaine composite material: add 100-200 parts of deionizations into 0.1-0.2 parts of graphene oxides Water, ultrasonic 40-50min are uniformly dispersed, and are warming up to 80-85 DEG C, and 2-4 parts of empgen BBs are added dropwise, and return stirring reacts 6- 8h, it is cooling, graphene oxide-glycine betaine composite material is dried to obtain in 80-85 DEG C.

4. a kind of method for arranging cotton bandage with the antifouling microcapsules of antibacterial according to claim 1, which is characterized in that step Suddenly the mass concentration of gum arabic powder solution is 90-100g/L in (2), and the mass concentration of water soluble chitosan solution is 15- 25g/L。

5. a kind of method for arranging cotton bandage with the antifouling microcapsules of antibacterial according to claim 1, which is characterized in that step Suddenly bleeding agent is penetrating agent JFC, pick-up 70-80% in (3).

Technical field

The invention belongs to bandage fields, and in particular to a method of cotton bandage is arranged with the antifouling microcapsules of antibacterial.

Background technique

In orthopaedics therapy, carrying out " fixation " using bandage is an important surgical measure.The stone being widely used at present Existing more than 100 years history of cream bandage, but plaster bandage still has many disadvantages in clinical application, and such as solidification is relatively slow, heavy Frangible, gas permeability and X-ray transparent are poor, and cannot enter water etc. after hardening.Therefore, external to have been had developed from the seventies " medical polymer bandage " replaces traditional plaster bandage, achieves good effect in clinical use.In the prior art Medical polymer bandage have the defects that resistant, antibacterial effect are poor, during use, it is easy to by spot dirt Dye, and then easily cause the generation of wound infection phenomenon.

Summary of the invention

The purpose of the present invention is being directed to existing problem, provides and a kind of arrange cotton bandage with the antifouling microcapsules of antibacterial Method, the modification cotton bandage according to this method preparation have excellent antibacterial bacteriostatic performance and resistant anti-pollution.

The present invention is achieved by the following technical solutions:

A method of arranging cotton bandage with the antifouling microcapsules of antibacterial, include the following steps, following raw materials by weight:

(1) the silicon fluoride treatment process of cotton bandage:

By finishing agent 1H, 1H, 2H, 2H- perfluoro capryl triethoxysilane, the 99-198 parts of dehydrated alcohols of 1-2 parts of low-surface-energies It is sufficiently mixed with 100-200 parts of deionized waters, it is 3 that glacial acetic acid, which is added dropwise, and adjusts pH, after hydrolyzing 30-40min, by bath raio 1:40 by alkali The cotton bandage of decrement treatment is immersed, and vibrates 1-2h in 90-95 DEG C of water-bath, take out silicon fluoride processing cotton it is taut Band；

Ultrasonic cleaning pretreatment first is carried out to cotton bandage with acetone, deionized water, removes greasy dirt, the dust of cotton bandage surface Equal impurity, then alkali decrement treatment is carried out to pretreatment cotton bandage with sodium hydroxide solution, work is introduced in cotton bandage surface Property group, activate material surface, generate that etch and increase its chemistry living by using Alkali reduction pretreatment cotton bandage surface Property, low-surface-energy processing is then carried out to alkali decrement treatment cotton bandage using silicon fluoride, after Alkali reduction-silicon fluoride joint arranges Cotton bandage surface presence-CH₃、-CF₂And the groups such as Si-O, material surface can be promoted to low when combining with silicon fluoride and arranging The absorption of surface energy finishing agent, the cotton bandage surface after arrangement have etching groove, and have obvious uniform particle attachment, make It obtains cotton bandage surface and has lower surface energy, to reach water, oil and soil repellent effect；

(2) preparation method of the antifouling microcapsules of antibacterial:

3.3-6.7 parts of gum arabic powder solution, In are added into 1-2 parts of barbaloin-graphene oxide-glycine betaine plural gels 0.67-1.3 parts of water soluble chitosan solution, the magnetic agitation in 40-45 DEG C of water bath with thermostatic control is added dropwise in stirring and dissolving at 40-45 DEG C 10-15min, the distilled water that equality of temperature same volume is added mix, and adjusting pH is 4-5, and constant temperature stirs multiple cohesion, and taking-up is cooled to 0-5 DEG C, 0.1-0.2 parts of glutaraldehyde cross-linking curing reaction 30-40min are added, it is antifouling micro- that standing filters, vacuum freeze drying obtains antibacterial Capsule；

Composite material is prepared using the compound empgen BB of graphene oxide, surface of graphene oxide contain a large amount of C=O, C=C ,-OH oxygen-containing functional group, for further with glycine betaine is compound provides functional group, in graphene oxide-glycine betaine composite material The carboxyl for belonging to graphene oxide disappears, and generates amide group, the two is successfully grafted；Coarse surface of graphene oxide is in lamella Graphene oxide-glycine betaine composite material configuration of surface of shape structure, synthesis is different from the smooth surface of glycine betaine, and is formed Reunion and porous structure；The hydrophobicity that graphene oxide is changed after grafting glycine betaine, becomes hydrophilic, by multiple with glycine betaine It closes, graphene oxide based nano-material has chemical activity；The composite material is strong to the cleaning dirt-removing power of albumen and greasy dirt；

Barbaloin-graphite oxide is prepared for using graphene oxide-glycine betaine, carbomer, barbaloin, triethanolamine as raw material again Alkene-glycine betaine plural gel；Using barbaloin-graphene oxide-glycine betaine plural gel as microcapsules core material, with Arab tree Rubber powder, water soluble chitosan are wall material, prepare the antifouling microcapsules of antibacterial by phase separation method, appearance is more regular and homogeneity compared with Good, in irregular spherical shape, barbaloin-graphene oxide-glycine betaine plural gel is wrapped in microcapsules, has sustained-release antibacterial Anti-fouling effect；

(3) padding process of cotton bandage:

The gained antifouling microcapsules 1:5 of antibacterial in (2) is added to the water, 2-3 parts of infiltrations are added in the magnetic agitation in 40-50 DEG C of water-bath Saturating agent obtains antibacterial antifouling finishing liquid, by the cotton bandage of gained silicon fluoride processing in (1) by bath raio 1:30 in antibacterial soil resistant finish 30-40min, roll compacting, double-steeping 30-40min, secondary roll compacting, the preliminary drying 10-20min at 40-50 DEG C, in 80- are impregnated in liquid Bake 5-10min at 100 DEG C, soap, wash, spontaneously drying antibacterial soil resistant finish cotton bandage；

The antifouling microcapsules of antibacterial are arranged in a manner of second dipping and rolling on cotton bandage, its excellent antibacterial soil resistance is assigned Can, finishing method process is simple, easy to operate；Cotton bandage after arrangement is preferable to the fungistatic effect of bacterium and fungi.

Further, in step (1) cotton bandage alkali decrement treatment technique: by mass concentration be 25g/L hydroxide Pretreated cotton bandage is immersed by sodium solution heating water bath to 75-90 DEG C, by bath raio 1:30-40, and 1-2 parts of promotions are added The hexadecyltrimethylammonium chloride of agent 2g/L, alkali decrement treatment 1-2h are washed to neutrality, are dried in 40-50 DEG C of baking oven To the cotton bandage of alkali decrement treatment；

The preprocess method of cotton bandage: being cleaned by ultrasonic 10-15min for cotton bandage in acetone, takes out, in deionized water After being cleaned by ultrasonic 5-10min, pretreated cotton bandage is dried to obtain in 55-60 DEG C of baking oven.

Further, barbaloin-graphene oxide-glycine betaine plural gel preparation in step (2): by 3-6 parts of card waves Nurse is swollen in deionized water, and 2-4 parts of barbaloins and 2-4 parts of graphene oxides-glycine betaine composite material is added, and ultrasound mixes, Stirring is lower to be added dropwise 1-2 parts of triethanolamines, obtains barbaloin-graphene oxide-glycine betaine plural gel；

The synthesis of graphene oxide-glycine betaine composite material: add 100-200 parts of deionizations into 0.1-0.2 parts of graphene oxides Water, ultrasonic 40-50min are uniformly dispersed, and are warming up to 80-85 DEG C, and 2-4 parts of empgen BBs are added dropwise, and return stirring reacts 6- 8h, it is cooling, graphene oxide-glycine betaine composite material is dried to obtain in 80-85 DEG C.

Further, the mass concentration of gum arabic powder solution is 90-100g/L, water soluble chitosan in step (2) The mass concentration of solution is 15-25g/L.

Further, bleeding agent is penetrating agent JFC, pick-up 70-80% in step (3).

The present invention has the advantage that compared with prior art

(1) ultrasonic cleaning pretreatment first carried out to cotton bandage with acetone, deionized water, remove cotton bandage surface greasy dirt, The impurity such as dust, then alkali decrement treatment is carried out to pretreatment cotton bandage with sodium hydroxide solution, it is introduced in cotton bandage surface Active group, activates material surface, generates by using Alkali reduction pretreatment cotton bandage surface and etches and increase its change Activity is learned, low-surface-energy processing is then carried out to alkali decrement treatment cotton bandage using silicon fluoride, Alkali reduction-silicon fluoride joint is whole Cotton bandage surface presence-CH after reason₃、-CF₂And the groups such as Si-O, material surface can be promoted when combining with silicon fluoride and arranging Absorption to low-surface-energy finishing agent, the cotton bandage surface after arrangement have etching groove, and have obvious uniform particle attached , enable cotton bandage surface to have lower surface, to reach water, oil and soil repellent effect.

(2) composite material is prepared using the compound empgen BB of graphene oxide, surface of graphene oxide contains greatly C=O, C=C ,-OH oxygen-containing functional group of amount, for further with glycine betaine is compound provides functional group, graphene oxide-glycine betaine is multiple The carboxyl for belonging to graphene oxide in condensation material disappears, and generates amide group, the two is successfully grafted；Surface of graphene oxide is thick It is rough in laminar structured, graphene oxide-glycine betaine composite material configuration of surface of synthesis is different from the smooth table of glycine betaine Face, and form reunion and porous structure；The hydrophobicity that graphene oxide is changed after grafting glycine betaine, becomes hydrophilic, passes through Compound with glycine betaine, graphene oxide based nano-material has chemical activity；Cleaning of the composite material to albumen and greasy dirt Dirt-removing power is strong；

Barbaloin-graphite oxide is prepared for using graphene oxide-glycine betaine, carbomer, barbaloin, triethanolamine as raw material again Alkene-glycine betaine plural gel；Using barbaloin-graphene oxide-glycine betaine plural gel as microcapsules core material, with Arab tree Rubber powder, water soluble chitosan are wall material, prepare the antifouling microcapsules of antibacterial by phase separation method, appearance is more regular and homogeneity compared with Good, in irregular spherical shape, barbaloin-graphene oxide-glycine betaine plural gel is wrapped in microcapsules, has sustained-release antibacterial Anti-fouling effect.

(3) the antifouling microcapsules of antibacterial are arranged in a manner of second dipping and rolling on cotton bandage, assigns its excellent antibacterial Anti-pollution, finishing method process is simple, easy to operate；Cotton bandage after arrangement to the fungistatic effect of bacterium and fungi compared with It is good.

Specific embodiment