阅读说明：本技术 基于sers微流控联的多点检测循环吸附系统 (Multi-point detection circulating adsorption system based on SERS micro-fluidic coupling ) 是由 周福敬 于 2019-09-22 设计创作，主要内容包括：本发明公开了基于SERS微流控联的多点检测循环吸附系统,属于提铀技术领域,基于SERS微流控联的多点检测循环吸附系统,包括与控制系统相连接的可切换式吸附系统和废液处理系统,可切换式吸附系统和废液处理系统之间连接有循环系统,循环系统包括狭长检测管道、污水排放阀、回流循环管道和污水循环阀,狭长检测管道内部连接有多点检测机构,可实现每次铀酰离子在可切换式吸附系统中接受吸附后对污水进行实时多点检测,且多点检测设置于狭窄的管道中,大大缩小了检测面积,实现全方位无死角检测,大大提高了检测精确度,并且根据实时检测数据通过控制系统控制未达指标的污水回流至吸附系统中,实现多次循环吸附,实现最终的高效排放。(the invention discloses a multipoint detection circulating adsorption system based on SERS micro-fluidic coupling, belonging to the technical field of uranium extraction, and comprising a switchable adsorption system and a waste liquid treatment system which are connected with a control system, wherein a circulating system is connected between the switchable adsorption system and the waste liquid treatment system, the circulating system comprises a long and narrow detection pipeline, a sewage discharge valve, a backflow circulating pipeline and a sewage circulating valve, a multipoint detection mechanism is connected in the long and narrow detection pipeline, so that real-time multipoint detection of sewage can be realized after uranyl ions are adsorbed in the switchable adsorption system every time, the multipoint detection is arranged in the narrow pipeline, the detection area is greatly reduced, omnibearing dead-angle-free detection is realized, the detection accuracy is greatly improved, and sewage which does not reach the index is controlled to flow back to the adsorption system through the control system according to real-time detection data, multiple times of circulating adsorption is realized, and the final high-efficiency discharge is realized.)

1. multipoint detection circulation adsorption system based on SERS micro-fluidic antithetical couplet, its characterized in that: the device comprises a switchable adsorption system and a waste liquid treatment system which are connected with a control system, wherein a circulating system is connected between the switchable adsorption system and the waste liquid treatment system, the circulating system comprises an elongated detection pipeline (1), a sewage discharge valve (2), a backflow circulating pipeline (3) and a sewage circulating valve (4), two ends of the elongated detection pipeline (1) are respectively connected with the switchable adsorption system and the waste liquid treatment system, one end of the backflow circulating pipeline (3) is connected with the switchable adsorption system, the other end of the backflow circulating pipeline (3) is communicated with one end, close to the waste liquid treatment system, of the elongated detection pipeline (1), the sewage discharge valve (2) is connected onto the elongated detection pipeline (1), the sewage circulating valve (4) is connected onto the backflow circulating pipeline (3), and a multi-point detection mechanism is connected into the elongated detection pipeline (1), and the multipoint detection mechanism is positioned between the switchable adsorption system and the sewage discharge valve (2).

2. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 1, wherein: the switchable adsorption system includes a tank adsorption system and a column adsorption system.

3. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 1, wherein: the multipoint detection mechanism comprises a plurality of mountain-type detection peak blocks (5), and the mountain-type detection peak blocks (5) are uniformly and fixedly connected to the inner wall of the long and narrow detection pipeline (1).

4. The SERS microfluidic-based multi-point detection cyclic adsorption system according to claim 3, wherein: the mountain-type detection peak blocks (5) are distributed on the inner wall of the long and narrow detection pipeline (1) in a staggered and annular mode, and the distance between every two adjacent mountain-type detection peak blocks (5) is 10-15 cm.

5. The SERS microfluidic-based multi-point detection cyclic adsorption system according to claim 4, wherein: the mountain-type peak detection block (5) comprises an ion detection block (51) and a reinforcing slope (52), the ion detection block (51) and the reinforcing slope (52) are both fixedly connected with the inner wall of the long and narrow detection pipeline (1), one end, close to the switchable adsorption system, of the ion detection block (51) is connected with a micro-fluidic chip, and the reinforcing slope (52) is fixedly connected to one end, far away from the micro-fluidic chip, of the ion detection block (51).

6. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 5, wherein: the reinforcing slope (52) is wedge-shaped, and a smooth coating is arranged on the surface of the reinforcing slope (52).

7. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 5, wherein: the height of the ion detection block (51) is 1/2-3/5 of the inner diameter of the long and narrow detection pipeline (1).

8. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 1, wherein: and a flow speed control unit is arranged at the sewage discharge valve (2).

9. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 2, wherein: uranium adsorbing materials are filled in the groove type adsorption system and the column adsorption system.

10. The SERS microfluidic-based multi-point detection cyclic adsorption system of claim 1, wherein: the length of the long and narrow detection pipeline (1) is 3-4m, and the long and narrow detection pipeline (1) is made of a hard plastic pipe.

Technical Field

The invention relates to the technical field of uranium extraction, in particular to a multi-point detection cyclic adsorption system based on SERS micro-fluidic coupling.

Background

With the decreasing global resources and the increasing population, people begin to explore and utilize unconventional reserve forms of industrial metals and minerals in order to prevent social, political and environmental factors from affecting energy supply safety and causing global economic problems. The main source of uranium is uranium asphalt ore UO, the distribution of uranium ore is concentrated, the storage capacity of economic uranium ores in 15 countries can meet the requirement of nuclear power generation development, and the total of Australia and Kazakhstan accounts for 33%. With the current uranium resource consumption rate, the worldwide uranium ore resource reserves can maintain the development of nuclear power for 80-120 years; however, by 2050, the total population of the whole world exceeds 130 hundred million, new economy is continuously developed, and the energy demand is doubled. In the past 20 years, although the energy consumption of the united states and developed countries is gradually reduced, the energy consumption at the global level is still improved by 30%; in the estimated 2040 years, the nuclear power generation capacity is doubled compared with that of the prior art, and the guarantee of the uranium resource reserve becomes the key for solving the problem of energy safety.

The uranium exists in the seawater in a stable state of Ca [ UO (CO) ], the concentration is 3.3 mu g L, although the concentration is very low, the total amount of uranium resources can reach 45 hundred million tons after being estimated due to huge global seawater, and the total amount of uranium resources is 1000 times of that of the traditional terrestrial uranium ore resources, so that the power generation sustainable development of human nuclear energy can be met for thousands of years. In order to guarantee the uranium resource supply of the countries with scarce uranium resources and prevent the uranium resource supply chain from generating rapid fluctuation, the research work of extracting uranium from the mature and low-carbon seawater is developed to meet the requirement of human beings on energy is imperative.

In the research of extracting uranium from seawater, the performance evaluation of a uranium adsorption material is critical. The performance of studying the uranium adsorption material at present mainly adopts the form of column adsorption, and has the disappearance to the adsorption form research of uranium adsorption material in real sea water, and research equipment's degree of automation is lower moreover, and is uncontrollable to the condition of uranium adsorption material in adsorption process. The device for researching the adsorption form of the uranium adsorption material in the real seawater is very important for researching the performance of the uranium adsorption material, and the adsorption condition is controllable.

Surface Enhanced Raman Scattering (SERS) is a novel trace characterization technique based on raman scattering. The SERS technology does not need a complex pretreatment process, is short in detection time consumption, fast in response and simple and convenient to operate, can carry out detection work in a complex field environment by combining an SERS substrate along with popularization of a miniaturized Raman spectrometer, and is a novel technology suitable for field detection of trace uranyl ions under a nuclear emergency condition. However, the existing SERS research mainly focuses on the adsorption rule and species analysis of uranyl ions, and reports of rapid, accurate, and high-throughput field detection of real environmental samples are still insufficient.

The Wanxiaolin researchers team of Chinese engineering physics research institute firstly designs double-stranded DNA which has specific recognition on UO22+ ions, and labels a reporter molecule rhodamine B (RhB) at the 5-bit end of a substrate chain. And respectively introducing the double-stranded DNA and the UO22+ ion solution to be detected into a pipeline of the microfluidic chip, and carrying out the DNase cleavage reaction in a microfluidic long and narrow U-shaped microchannel. After reaction, substrate chains of the double-stranded DNA are broken at the rA site, and cleavage products marked with RhB are shunted into three parallel samples for high-throughput parallel testing of three SERS biochips. SERS biochips are three-dimensional ordered arrays of ZnO-Ag mesoporous nanoplatelets that have been modified with single-stranded dna (ssDNA), where ssDNA is a sequence complementary to 5' -RhB-labeled lytic dna (csdna) in the reaction product. After the two are annealed into a double chain, the reporter molecule RhB is attached to the surface of the three-dimensional ZnO-Ag composite substrate to generate a Raman signal. The concentration of UO22+ is indirectly changed by the strength of Raman signal. The detection Limit (LOD) of the sensor to UO22+ is 3.71X 10-15M by establishing a standard curve and according to a calculation formula. This result clearly meets the requirements of the U.S. Environmental Protection Agency (EPA) (130 nM). This is currently the most sensitive method for UO22+ ion detection compared to other analytical methods reported in the last two years. In addition, when the concentration of UO22+ ion is only 0.005% of the concentration of other 15 toxic metal ions, the biosensor can still show excellent ability to selectively recognize UO22+ ion. Next, the authors tested five different concentrations (n = 6) of tap water and river water that mimic contamination with UO22+ ions using biosensors. By washing the buffer solution, the chip was reused 2 times, and 6 parallel data were obtained for each concentration level, indicating its efficient detection capability. Meanwhile, the recovery rate of the samples with five different concentrations (n = 6) is 95.2% -106.3%, and the RSD value is 2.6% -5.8%. In addition, the whole DNase cleavage reaction and high-throughput parallel detection can be carried out more than 3 times on the reusable SERS-microfluidic biosensor.

At present, need urgently to develop one set of automatic controllable uranium adsorption system, but during uranyl ion detection among the current uranium adsorption system, often only simple sample detection or small region detect when detecting, detect not comprehensively, the degree of accuracy of testing result is low, leads to the uranyl ion content in the sewage not to reduce the index and just discharge, aggravates the polluted environment.

Disclosure of Invention

1. Technical problem to be solved

Aiming at the problems in the prior art, the invention aims to provide a SERS micro-fluidic coupling-based multi-point detection circulating adsorption system, which can realize real-time multi-point detection on sewage after adsorption of uranyl ions is completed each time, and the multi-point detection is arranged in a narrow pipeline, so that the detection area is greatly reduced, omnibearing non-dead-angle detection is realized, the detection accuracy is greatly improved, sewage which does not reach indexes is controlled to flow back into the adsorption system through a control system according to real-time detection data, multiple circulating adsorption is realized, and the final efficient discharge is realized.

2. Technical scheme

In order to solve the above problems, the present invention adopts the following technical solutions.

The multi-point detection circulating adsorption system based on SERS micro-fluidic coupling comprises a switchable adsorption system and a waste liquid treatment system which are connected with a control system, wherein a circulating system is connected between the switchable adsorption system and the waste liquid treatment system, the circulating system comprises a long and narrow detection pipeline, a waste liquid discharge valve, a backflow circulating pipeline and a sewage circulating valve, two ends of the long and narrow detection pipeline are respectively connected with the switchable adsorption system and the waste liquid treatment system, one end of the backflow circulating pipeline is connected with the switchable adsorption system, the other end of the backflow circulating pipeline is communicated with one end, close to the waste liquid treatment system, of the long and narrow detection pipeline, the sewage discharge valve is connected onto the long and narrow detection pipeline, the sewage circulating valve is connected onto the backflow circulating pipeline, a multi-point detection mechanism is connected inside the long and narrow detection pipeline, and the multi-point detection mechanism is positioned between the switchable adsorption, can realize that uranyl ion accepts in switchable formula adsorption system at every turn and adsorbs the back and carry out real-time multiple spot to sewage and detect, and the multiple spot detects and sets up in constrictive pipeline, has reduced detection area greatly, realizes that all-round no dead angle detects, has improved the detection accuracy greatly to in controlling the sewage that does not reach the index through control system according to real-time detection data backward flow to adsorption system, realize manifold cycles and adsorb, realize ultimate high-efficient emission.

Furthermore, the switchable adsorption system comprises a groove type adsorption system and a column adsorption system, uranium adsorption materials are filled in the groove type adsorption system and the column adsorption system, a stirring groove for adsorption operation is arranged in the groove type adsorption system, and the switchable adsorption system has the advantages of simple and compact structure, small volume and high efficiency, can effectively adsorb uranyl ions in sewage, improve the sewage purification performance, separate each component by different adsorption force of the adsorbent in the column adsorption system to each component of the sewage, and the uranyl ions are effectively adsorbed, the content of the uranyl ions in the sewage can be effectively reduced, a technician selects a proper adsorption system according to the actual content of the uranyl ions in the sewage, the adsorption device for uranium in aqueous solution, which is obtained by earlier experiments, for example, the adsorption device for uranium in aqueous solution proposed in chinese patent application No. CN201811272422.9, can be designed by referring to the scheme of the adsorption condition for uranium in the patent.

Furthermore, the multipoint detection mechanism comprises a plurality of mountain-type detection peak blocks which are uniformly and fixedly connected on the inner wall of the long and narrow detection pipeline, the long and narrow detection pipeline can limit the throughput of sewage, the detection area is greatly reduced, a large amount of sewage passing through is contacted with the mountain-type detection peak blocks and is detected, the omnibearing dead-angle-free detection is realized, the detection accuracy is greatly improved, in addition, the mountain-type detection peak blocks are distributed on the inner wall of the long and narrow detection pipeline in a staggered and annular mode, the mountain-type detection peak blocks have certain blocking effect on the sewage flowing through, the blocking effect can form a stirring effect on the sewage, the distribution of uranyl ions in the flowing sewage is more uniform, the detection is more accurate, the distance between two adjacent mountain-type detection peak blocks is 10-15cm, the space can ensure that the mountain-type detection peak blocks are not wasted and the manufacturing process is not aggravated, the optimal detection effect is realized; if the distance is too small, manufacturing materials of the mountain-type detection peak block are wasted, the manufacturing process is aggravated, and if the distance is too small, sewage flow is easy to be too small, and the drainage rate is reduced; too big difficult multiple spot detection mechanism that utilizes of distance forms the stirring effect to sewage, reduces detection accuracy.

Furthermore, the mountain-type detection peak block comprises an ion detection block and a reinforcing slope, the ion detection block and the reinforcing slope are both fixedly connected with the inner wall of the long and narrow detection pipeline, one end, close to the switchable adsorption system, of the ion detection block is connected with a micro-fluidic chip, the micro-fluidic chip has high-efficiency detection capacity, the reinforcing slope is fixedly connected to one end, far away from the micro-fluidic chip, of the ion detection block, sewage is introduced into the waste liquid treatment system through the switchable adsorption system, and the reinforcing slope is located at one end, back of the ion detection block, so that the impact force of the sewage on the ion detection block can be reduced, and the sewage is prevented from flushing the ion detection block.

Further, the reinforcement slope is wedge-shaped, and reinforcement slope surface is equipped with smooth coating, and wedge-shaped reinforcement slope can bear great impact force, guarantees that the micro-fluidic chip on the ion detection piece detects steadily, and the smooth coating on the reinforcement slope surface can reduce the impact force of sewage to the reinforcement slope, still can effectively protect the difficult impaired of reinforcement slope.

Furthermore, the height of the ion detection block is 1/2-3/5 of the inner diameter of the long and narrow detection pipeline, the height can ensure that the best detection effect is realized on the basis of not aggravating the manufacturing process, the height is too low, a multi-point detection mechanism is not easy to form an efficient stirring effect on sewage, and the detection accuracy is reduced; too high height may aggravate the manufacturing process, and may easily cause too small sewage flow rate and decrease the drainage rate.

Furthermore, a flow rate control unit is arranged at the sewage discharge valve and can be used for finally controlling the sewage discharge speed, the optimal flow rate control needs to be determined according to the content of uranyl ions in the actual sewage, and the optimal flow rate control can play an important role in removing the uranyl ions.

Furthermore, the length of the long and narrow detection pipeline is 3-4m, the long and narrow detection pipeline is made of hard plastic pipes, the hard long and narrow detection pipeline can ensure that the pipeline is not easy to bend, so that the influence on a multipoint detection mechanism inside the hard long and narrow detection pipeline is not easy to cause, the multipoint detection mechanism is ensured to normally exert the detection function, the long and narrow detection pipeline is too short, the number of mountain-shaped detection peak blocks is reduced, the accuracy to be measured is reduced, the pipe is wasted if the long and narrow detection pipeline is too long, the drainage time is prolonged to a certain extent, and the drainage rate is reduced.

3. Advantageous effects

Compared with the prior art, the invention has the advantages that:

(1) This scheme is at long and narrow detection pipeline internal connection multiple spot detection mechanism, can realize that each time the uranyl ion accepts to adsorb the back and carry out real-time multiple spot detection to sewage in switchable formula adsorption system, and the multiple spot detects and sets up in constrictive pipeline, has reduced detection area greatly, realizes all-round no dead angle and detects, has improved the detection accuracy greatly, and in passing through the sewage backward flow that control system control did not reach the index to adsorption system according to real-time detection data, realize manifold cycles and adsorb, realize ultimate high-efficient emission.

(2) The multipoint detection mechanism comprises a plurality of mountain-type detection peak blocks which are uniformly and fixedly connected on the inner wall of the long and narrow detection pipeline, the long and narrow detection pipeline can limit the throughput of sewage, the detection area is greatly reduced, a large amount of sewage which passes through is contacted with the mountain-type detection peak blocks and is detected, the omnibearing detection without dead angles is realized, the detection accuracy is greatly improved, in addition, the mountain-type detection peak blocks are distributed on the inner wall of the long and narrow detection pipeline in a staggered and annular mode, the mountain-type detection peak blocks have certain blocking effect on the sewage which flows through, the blocking effect can form a stirring effect on the sewage, the distribution of uranyl ions in the flowing sewage is more uniform, the detection is more accurate, the distance between two adjacent mountain-type detection peak blocks is 10-15cm, and the distance can ensure that the mountain-type detection peak blocks are not wasted and the manufacturing process is not aggravated, the optimal detection effect is realized; if the distance is too small, manufacturing materials of the mountain-type detection peak block are wasted, the manufacturing process is aggravated, and if the distance is too small, sewage flow is easy to be too small, and the drainage rate is reduced; too big difficult multiple spot detection mechanism that utilizes of distance forms the stirring effect to sewage, reduces detection accuracy.

(3) Mountain-type detects peak piece and includes ion detection piece and reinforcement slope, ion detection piece and reinforcement slope all with long and narrow detection pipeline's inner wall fixed connection, the one end that ion detection piece is close to switchable formula adsorption system is connected with micro-fluidic chip, micro-fluidic chip has efficient detection ability, reinforcement slope fixed connection keeps away from micro-fluidic chip's one end in the ion detection piece, sewage lets in waste liquid treatment system by switchable formula adsorption system, the reinforcement slope is located the one end of ion detection piece back of the body water, can alleviate the impact force of sewage to the ion detection piece, prevent that sewage from the ion detection piece from dashing away from long and narrow detection pipeline's inner wall.

(4) The reinforcement slope is the wedge, and reinforcement slope surface is equipped with smooth coating, and wedge-shaped reinforcement slope can bear great impact force, guarantees that the micro-fluidic chip on the ion detection piece detects steadily, and smooth coating on the reinforcement slope surface can reduce sewage to the impact force on reinforcement slope, still can effectively protect the difficult impaired of reinforcement slope.

(5) The height of the ion detection block is 1/2-3/5 of the inner diameter of the long and narrow detection pipeline, the height can ensure that the best detection effect is realized on the basis of not aggravating the manufacturing process, the height is too low, the efficient stirring effect on sewage is not easy to form by utilizing a multipoint detection mechanism, and the detection accuracy is reduced; too high height may aggravate the manufacturing process, and may easily cause too small sewage flow rate and decrease the drainage rate.

(6) The sewage discharge valve is provided with a flow rate control unit which can carry out final control on the speed of sewage discharge, the optimal flow rate control needs to be determined according to the content of uranyl ions in the actual sewage, and the optimal flow rate control can play an important role in removing the uranyl ions.

(7) The length of the long and narrow detection pipeline is 3-4m, the long and narrow detection pipeline is made of hard plastic pipes, the hard long and narrow detection pipeline can ensure that the pipeline is not easy to bend, so that the influence on a multipoint detection mechanism inside the pipeline is not easy to cause, the multipoint detection mechanism is ensured to normally exert the detection function, the long and narrow detection pipeline is too short, the number of mountain-shaped detection peak blocks is reduced, the accuracy of detection is reduced, the pipe is wasted if the long and narrow detection pipeline is too long, the drainage time is prolonged to a certain extent, and the drainage rate is reduced.

Drawings

FIG. 1 is a schematic structural view of the present invention in a state where both a tank-type adsorption system and a column adsorption system are used;

FIG. 2 is a schematic structural view of a single-use tank-type adsorption system according to the present invention;

FIG. 3 is a schematic view of the single-column adsorption system according to the present invention;

FIG. 4 is a schematic view of a partial cross-sectional structure at A in FIGS. 1, 2 and 3;

FIG. 5 is a schematic view of the structure at B in FIG. 4;

FIG. 6 is a schematic cross-sectional view of an elongated inspection pipe of the present invention.

The reference numbers in the figures illustrate:

The device comprises a long and narrow detection pipeline 1, a sewage discharge valve 2, a backflow circulation pipeline 3, a sewage circulation valve 4, a mountain-type detection peak block 5, an ion detection block 51 and a reinforced slope 52.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention; it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by those skilled in the art without any inventive work are within the scope of the present invention.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.