阅读说明：本技术 一种医用彩色橡胶滴头及其制备方法 (Medical colored rubber dropper and preparation method thereof ) 是由 闫礼 卢晨灏 马瑞欣 陈雪姣 杨树林 魏晓翠 王子梦 商杰欣 李岱岳 陈明 曾海 于 2021-08-31 设计创作，主要内容包括：本发明公开了一种医用彩色橡胶滴头及其制备方法,包括以下重量份的组分：聚异戊二烯橡胶100份、硫化剂1～4份、促进剂0.5～3份、ZnO 2～10份、硬脂酸1～3份、煅烧陶土15～20份、抗氧剂1076 0.5～1份、硅油1～3份和着色剂,本发明通过对配方和工艺的创新优化,保证了与药品的相容性及产品稳定性,且抗老化性能和化学性能更优异、颜色多样,满足婴幼儿用药产品市场新的快速发展需求；同时,有较高的产品定伸强力,保证产品在脱模过程中不易变形或碎裂。(The invention discloses a medical colored rubber dropper and a preparation method thereof, wherein the medical colored rubber dropper comprises the following components in parts by weight: 100 parts of polyisoprene rubber, 1-4 parts of vulcanizing agent, 0.5-3 parts of accelerator, 2-10 parts of ZnO, 1-3 parts of stearic acid, 15-20 parts of calcined argil, 10760.5-1 parts of antioxidant, 1-3 parts of silicone oil and colorant, the invention ensures the compatibility with medicines and the product stability through the innovation and optimization of the formula and process, has more excellent ageing resistance and chemical property and various colors, and meets the new rapid development requirement of the infant medicine product market; meanwhile, the product has higher stretching strength, and ensures that the product is not easy to deform or crack in the demoulding process.)

1. A medical color rubber dripper is characterized in that: the raw rubber is polyisoprene rubber.

2. The medical colored rubber dripper of claim 1, wherein: the paint comprises the following components in parts by weight: 100 parts of polyisoprene rubber, 1-4 parts of vulcanizing agent, 0.5-3 parts of accelerator, 2-10 parts of ZnO, 1-3 parts of stearic acid, 15-20 parts of calcined pottery clay, 10760.5-1 part of antioxidant, 1-3 parts of silicone oil and colorant.

3. The medical colored rubber dripper according to claim 2, wherein: the colorant comprises 3-15 parts of titanium dioxide and 0.1-10 parts of carbon black or 1-10 parts of ferric oxide or 1-7 parts of taijing blue.

4. The medical colored rubber dripper according to claim 2, wherein: the vulcanizing agent is sulfur, and the accelerator is TRA.

5. The preparation method of the medical colored rubber dripper of claim 1, wherein the preparation method comprises the following steps: the method comprises the following specific steps:

s1, mixing rubber: accurately weighing each component, cutting rubber into blocks, adding the rubber blocks into an internal mixer for internal mixing, transferring the internal mixing rubber to an open mill for discharging and sheet discharging, cooling a hanging rack, rolling or horizontally placing, standing the rubber material for not less than 24 hours, and sending the rubber material to the next process for use;

wherein, the charging sequence is as follows: firstly adding polyisoprene rubber and a coloring agent, then adding an antioxidant 1076, zinc oxide, stearic acid, calcined argil and silicone oil, and finally adding an accelerator and a vulcanizing agent;

s2, molding: sheeting by a four-roller calender, cooling to room temperature by an 8-roller cooling machine, cutting into pieces, cutting into strips and weighing by an automatic cutting machine;

s3, vulcanization: putting the sheet obtained in the step S2 into a vulcanizing machine for vulcanization;

s4, trimming: after vulcanization, the whole piece is automatically punched, automatically positioned by a manipulator, automatically placed, punched and discharged;

s5, cleaning: cleaning the product in a ten thousand grade clean area by using purified water without a heat source, cooling the product to room temperature and discharging the product;

s6, packaging: double-layer aseptic bags are used for packaging, and the outer package is packaged by double-layer corrugated cartons.

6. The preparation method of the medical colored rubber dropper according to claim 5, wherein the preparation method comprises the following steps: the banburying conditions in the step S1 are as follows: the top plug pressure is 0.6Mpa, the banburying temperature is 110 plus or minus 5 ℃, and the banburying time is 10 minutes.

7. The preparation method of the medical colored rubber dropper according to claim 5, wherein the preparation method comprises the following steps: and in the step S1, cooling the racks to below 60 ℃.

8. The preparation method of the medical colored rubber dropper according to claim 5, wherein the preparation method comprises the following steps: the temperature of the four-roll calender in the step S2 is 70 +/-5 ℃.

9. The preparation method of the medical colored rubber dropper according to claim 5, wherein the preparation method comprises the following steps: the sulfurization conditions in the step S3 are as follows: the temperature is 150 +/-10 ℃, the pressure is 20 +/-3 Mpa, and the time is 4 +/-1 minute.

10. The preparation method of the medical colored rubber dropper according to claim 5, wherein the preparation method comprises the following steps: the cleaning temperature in the step S5 is 80 +/-5 ℃.

Technical Field

The invention relates to a medical colored rubber dropper and a preparation method thereof, belonging to the field of medical rubber.

Background

The invention relates to a rubber dropper which is a medicine feeding device applied to infants. Wherein, the medicine feeding device comprises three parts of a rubber dropper, a dropper tube body and a measuring cup. The rubber dropper is used for sucking air in the dropper to enable liquid medicine to enter the dropper, and the liquid medicine can be directly dripped into the mouth of an infant or a measuring cup. The rubber dropper can be used for a medicine feeding device and also can be used for chemical experiments, such as sucking a small amount of chemical reagents to perform chemical reaction operation, or sucking and dripping medicines in the pharmaceutical industry. The method has the advantages of simple and convenient operation, cleanness, safety, stable quality and accurate and reliable test data, and is generally applied to various medical institutions and medicine research and development institutions.

However, the existing rubber drippers have poor aging resistance, unstable product quality, deep color, serious fading and certain odor, contain non-rubber substances such as protein, fatty acid and the like, and cannot meet the regulatory requirements of direct contact with medicines.

Therefore, people always improve the formula and the production process of the rubber dripper, but because the internal structure of a rubber dripper product is complex and the height of the dripper is high, namely the depth of a groove of the mold dripper is deep during processing, the dripper has high requirement on the stretching strength of the dripper in order to ensure that the dripper is not easy to deform or crack in the demolding process, and the development of the rubber dripper is always restricted.

Disclosure of Invention

The technical problem to be solved by the invention is to provide the medical colored rubber dropper and the preparation method thereof, which can increase the stretching strength of a product, ensure that the product is not easy to deform or crack in the demolding process, and have more excellent anti-aging performance and chemical performance.

In order to solve the technical problems, the technical scheme adopted by the invention is as follows:

a medical color rubber dropper, wherein the raw rubber is polyisoprene rubber.

The technical scheme of the invention is further improved as follows: the paint comprises the following components in parts by weight: 100 parts of polyisoprene rubber, 1-4 parts of vulcanizing agent, 0.5-3 parts of accelerator, 2-10 parts of ZnO, 1-3 parts of stearic acid, 15-20 parts of calcined pottery clay, 10760.5-1 part of antioxidant, 1-3 parts of silicone oil and colorant.

The technical scheme of the invention is further improved as follows: the colorant comprises 3-15 parts of titanium dioxide and 0.1-10 parts of carbon black or 1-10 parts of ferric oxide or 1-7 parts of taijing blue.

The technical scheme of the invention is further improved as follows: the vulcanizing agent is sulfur, and the accelerator is TRA.

The technical scheme of the invention is further improved as follows: the method comprises the following specific steps:

s1, mixing rubber: accurately weighing each component, cutting rubber into blocks, adding the rubber blocks into an internal mixer for internal mixing, transferring the internal mixing rubber to an open mill for discharging and sheet discharging, cooling a hanging rack, rolling or horizontally placing, standing the rubber material for not less than 24 hours, and sending the rubber material to the next process for use;

wherein, the charging sequence is as follows: firstly adding polyisoprene rubber and a coloring agent, then adding an antioxidant 1076, zinc oxide, stearic acid, calcined argil and silicone oil, and finally adding an accelerator and a vulcanizing agent;

s2, molding: sheeting by a four-roller calender, cooling to room temperature by an 8-roller cooling machine, cutting into pieces, cutting into strips and weighing by an automatic cutting machine;

s3, vulcanization: putting the sheet obtained in the step S2 into a vulcanizing machine for vulcanization;

s4, trimming: after vulcanization, the whole piece is automatically punched, automatically positioned by a manipulator, automatically placed, punched and discharged;

s5, cleaning: the product is cleaned by purified water without heat source in a ten thousand grade clean area, and cooled to room temperature for discharge.

S6, packaging: double-layer aseptic bags are used for packaging, and the outer package is packaged by double-layer corrugated cartons.

The technical scheme of the invention is further improved as follows: the banburying conditions in the step S1 are as follows: the top plug pressure is 0.6Mpa, the banburying temperature is 110 plus or minus 5 ℃, and the banburying time is 10 minutes.

The technical scheme of the invention is further improved as follows: and in the step S1, cooling the racks to below 60 ℃.

The technical scheme of the invention is further improved as follows: the temperature of the four-roll calender in the step S2 is 70 +/-5 ℃.

The technical scheme of the invention is further improved as follows: the sulfurization conditions in the step S3 are as follows: the temperature is 150 +/-10 ℃, the pressure is 20 +/-3 Mpa, and the time is 4 +/-1 minute.

The technical scheme of the invention is further improved as follows: the cleaning temperature in the step S5 is 80 +/-5 ℃.

Due to the adoption of the technical scheme, the invention has the technical progress that:

the formula and the process are innovated and optimized, so that the compatibility with medicines and the product stability are ensured, the anti-aging performance and the chemical performance are more excellent, the colors are various, and the new rapid development requirement of the infant medicine feeding market is met; meanwhile, the product has higher stretching strength, and ensures that the product is not easy to deform or crack in the demoulding process.

Drawings

FIG. 1 is a process flow diagram of the present invention.

Detailed Description

The present invention will be described in further detail with reference to the following examples:

example 1: grey rubber water dropper

TABLE 1 Grey rubber dropper composition Table

The preparation process is shown in figure 1:

s1, mixing rubber: accurately weighing the components according to the following table 1, wherein the rubber is cut into blocks and added into an internal mixer for internal mixing, and the internal mixing conditions are as follows: the top plug pressure is 0.6Mpa, the maximum banburying temperature is 115 ℃, and the banburying time is 10 minutes. The charging sequence is as follows: firstly adding polyisoprene rubber and a coloring agent, then adding an antioxidant 1076, zinc oxide, stearic acid, calcined argil and silicone oil, and finally adding an accelerator and a vulcanizing agent;

and then transferring the banburying adhesive to an open mill for discharging and sheet discharging, cooling the hanging rack to below 60 ℃, rolling or horizontally placing, standing the adhesive for not less than 24 hours, and sending the adhesive to the next process for use.

S2, molding: sheeting by a four-roller calender at the temperature of 70 +/-5 ℃, cooling to room temperature by an 8-roller cooling machine, cutting, slitting and weighing by an automatic cutting machine, wherein the standard weight tolerance of the film is +/-5 g, and rechecking and weighing by an artificial electronic scale.

S3, vulcanization: the sheet obtained in step S2 is put into a vulcanizer to be vulcanized, and the vulcanization conditions are as follows: the temperature is 150 +/-10 ℃, the pressure is 20 +/-3 Mpa, and the time is 4 +/-1 minute.

S4, trimming: after vulcanization, the whole piece is automatically punched, the manipulator is automatically positioned, and the material is automatically placed and punched and discharged.

S5, cleaning: the product is cleaned by purified water without heat source in a ten thousand grade clean area, the cleaning temperature is 80 plus or minus 5 ℃, and the product is cooled to room temperature and discharged.

S6, packaging: double-layer aseptic bags are used for packaging, and the outer package is packaged by double-layer corrugated cartons.

Example 2: red rubber water dropper

TABLE 2 Red rubber dripper component Table

The preparation process was the same as in example 1.

Example 3: blue rubber water dropper

TABLE 3 blue rubber drop head composition table

The preparation process was the same as in example 1.

And (3) performance detection:

[ physical Properties ]

Sealing property: take 10 of this product, insert into dropper each one. The dropper is pinched by hand, the dropper is vertically inserted into the water, and the dropper is released, so that the water can be sucked to more than three-fourths of the volume of the dropper. The dropper was removed and observed for 30 seconds. No more than 1 drop of water per one plant should naturally drip.

And (3) measuring the tensile property: performed according to GB/T528-2009.

And (3) hardness measurement: performed according to GB/T531-2008.

The performance test results are shown in the following table:

TABLE 4 Performance test Table