阅读说明：本技术 动物原位吸药设备 (Animal in-situ medicine suction equipment ) 是由 陈欢 刘光林 侯宏卫 刘明达 田雨闪 丁政 付亚宁 李凯欣 韩书磊 王红娟 李俊 于 2021-06-21 设计创作，主要内容包括：本发明公开了一种动物原位吸药设备,包括操作室、储药箱、第一感应装置、传感器及控制器,操作室用于容纳动物；第一感应装置包括第一漏斗和第二漏斗,第二漏斗套设安装在第一漏斗内且密封安装在安装孔内；储药箱包括与控制器通信连接的阀门；传感器与控制器通信连接,传感器包括之间设置有红外线的感应端和发射端；当动物的鼻子伸进第二漏斗的喇叭口内时,阻挡了红外线的传播路径,此时控制器控制阀门开启；当动物的鼻子离开第二漏斗的喇叭口时,控制器控制阀门关闭；第一漏斗的喇叭口处设置有负压。本发明提供的动物原位吸药设备,避免了动物全身暴漏在雾化药环境下,降低了雾化药对动物身体的损伤,提高了动物对药品成瘾性实验结果的准确性。(The invention discloses an animal in-situ medicine suction device which comprises an operation chamber, a medicine storage box, a first sensing device, a sensor and a controller, wherein the operation chamber is used for accommodating animals; the first induction device comprises a first funnel and a second funnel, and the second funnel is sleeved in the first funnel and hermetically arranged in the mounting hole; the medicine storage box comprises a valve which is in communication connection with the controller; the sensor is in communication connection with the controller and comprises an induction end and an emission end, and infrared rays are arranged between the induction end and the emission end; when the nose of the animal extends into the bell mouth of the second funnel, the transmission path of the infrared ray is blocked, and the controller controls the valve to be opened; when the nose of the animal leaves the bell mouth of the second funnel, the controller controls the valve to be closed; the bell mouth of the first funnel is provided with negative pressure. The animal in-situ drug suction equipment provided by the invention avoids the whole body of an animal from leaking in the atomized drug environment, reduces the damage of the atomized drug to the animal body, and improves the accuracy of the experimental result of the animal on drug addiction.)

1. The utility model provides an animal normal position inhales medicine equipment which characterized in that, includes transparent control chamber, contains the explosive box, first induction system, sensor and the controller of atomizing medicine, wherein:

the operation room is used for accommodating animals and comprises an installation surface, and installation holes are formed in the installation surface;

the first induction device comprises a first funnel and a second funnel, the bell mouth of the first funnel and the bell mouth of the second funnel are arranged on the same side, the second funnel is sleeved in the first funnel, and the bell mouth of the first funnel faces the inside of the operation chamber and is hermetically arranged in the installation hole;

the medicine storage box is communicated with the inner channel of the second hopper and used for providing atomized medicines for the animals, and the medicine storage box comprises a valve which is in communication connection with the controller; the sensor is in communication connection with the controller and comprises an induction end and an emission end, the induction end and the emission end are respectively installed at two opposite ends of the bell mouth of the second funnel, and infrared rays are arranged between the emission end and the induction end;

when the nose of the animal extends into the bell mouth of the second funnel, the nose of the animal blocks the propagation path of the infrared rays, and the controller controls the valve to be opened to provide the atomized medicine to the animal; when the nose of the animal leaves the bell mouth of the second funnel, the controller controls the valve to be closed to stop supplying the atomized medicine;

the bell mouth department of first funnel is provided with the negative pressure for will remain the atomized medicine in the control chamber discharges the control chamber.

2. The animal in-situ medicine suction device as claimed in claim 1, wherein the time interval between the opening of the two adjacent valves is set as t, and the time interval between the nose of the animal extending into the bell mouth of the second funnel is set as t₁When t is₁When t is less than or equal to t, the valve is closed, and when t is less than or equal to t₁And when the value is larger than t, the valve is opened.

3. The animal in situ drug intake apparatus of claim 2, wherein the drug reservoir comprises a pressurized air pump in communication with the controller, the pressurized air pump delivering the aerosolized drug to the second hopper when the valve is opened.

4. The animal in-situ medicine suction device according to claim 3, further comprising a waste gas adsorption box, a gas recovery pump, a recovery conduit and a communication conduit, wherein the gas recovery pump is in communication connection with the controller, one end of the recovery conduit is in sealed communication with the tail of the first funnel, the other end of the recovery conduit is in sealed communication with the waste gas adsorption box, and the waste gas adsorption box and the gas recovery pump are in sealed communication through the communication conduit.

5. The animal in situ drug uptake apparatus of claim 4, wherein the first sensing device further comprises at least one support bracket mounted between an outer sidewall of the second funnel and an inner sidewall of the first funnel.

6. The animal in-situ medicine suction device according to claim 5, further comprising a second sensing device, wherein the structure of the second sensing device is the same as that of the first sensing device, the number of the mounting holes is two, the first sensing device and the second sensing device are respectively and correspondingly and hermetically mounted in the two mounting holes, and the second sensing device is communicated with the gas recovery pump, so that the second sensing device generates negative pressure at the corresponding bell mouth of the first funnel.

7. The animal in-situ medicine suction device according to claim 6, further comprising an atomized medicine generation box and a smoke concentration sensor, wherein the smoke concentration sensor is installed in the medicine storage box, and is communicated with the controller; the atomizing medicine produce the case with the explosive box is linked together, the atomizing medicine produces and is provided with the electron smog spinning disk atomiser that is used for atomizing the medicine on the case, electron smog spinning disk atomiser with the controller is linked together, works as smoke concentration sensor detects in the explosive box when the concentration of atomizing medicine is less than first threshold value, controller control electron smog spinning disk atomiser opens in order to produce atomizing medicine.

8. The animal in-situ medicine suction device according to claim 7, further comprising an air pressure sensor and a pressure release valve, wherein the air pressure sensor is installed in the medicine storage box, the medicine storage box further comprises a connecting surface, a pressure release hole is formed in the connecting surface, the pressure release valve is installed in the pressure release hole in a sealing mode, the pressure release valve is in communication connection with the controller, and when the air pressure sensor detects that the pressure in the medicine storage box exceeds a second threshold value, the controller controls the pressure release valve to be opened so that the pressure in the medicine storage box is reduced to be smaller than or equal to the second threshold value.

9. The animal in-situ medicine suction device according to claim 8, further comprising a sound generator, a first prompting lamp, a second prompting lamp and a cage lamp, wherein the sound generator, the first prompting lamp, the second prompting lamp and the cage lamp are all installed in the operating room, the first prompting lamp is installed on one side of the first induction device, the second prompting lamp is installed on one side of the second induction device, and the sound generator, the first prompting lamp, the second prompting lamp and the cage lamp are all electrically connected with the controller.

10. The animal in-situ medicine suction device according to claim 9, further comprising a sound insulation box, wherein the sound insulation box is sleeved outside the operation room, the first sensing device and the second sensing device, and an ambient noise fan is installed on the sound insulation box.

11. The animal in situ aspiration drug device of claim 10, wherein the chamber further comprises a plurality of conductive metal rods electrically connected to the controller, the plurality of conductive metal rods being tiled above the bottom of the chamber with a gap therebetween, wherein a removably mounted collection box is provided in the gap for collecting the feces and urine of the animal.

12. The animal in situ drug uptake apparatus of any of claims 1-11, wherein at least one of the first and second sensing devices is integrally formed.

Technical Field

The invention relates to the technical field of animal addiction behaviors, in particular to an animal in-situ medicine suction device.

Background

The self-administration experiment is a common method for behavioral and pharmacological research, is widely applied to the field of drug addiction behavioral research, utilizes the positive reinforcement effect (the effect of generating special psychological experience and mental feeling) of certain drugs, controls animals to do specified actions according to set experimental steps, and gives certain excitation to the animals (rats, mice, monkeys and the like are frequently adopted), so that the animals establish the connection between behaviors and rewards, and further simulate the drug addiction condition of human beings.

At present, the common intake method of most of the addictive substances is oral-nasal inhalation (including smoking, nasal inhalation, oral-nasal inhalation and the like), and the medicines inhaled from the mouth and the nose are generally atomized and then enter an artery through a respiratory tract for circulation. In the prior art, the experiment about aerosol administration has the following problems that for example, the whole body of an animal is exposed to the environment of the atomized medicine, the atomized medicine can not only damage the skin, eyes and ears of the animal, but also reduce the accuracy of the experiment result of the addiction of the animal to the medicine.

Disclosure of Invention

In view of this, the present invention provides an in-situ drug inhalation apparatus for animals, so as to prevent the animals from leaking into the environment of atomized drug, reduce the damage of the atomized drug to the animal body, and improve the accuracy of the experimental result of the animal addiction to the drug.

Based on the above purpose, the present invention provides an animal in-situ drug-sucking device, comprising a transparent operating room, a drug storage box containing atomized drugs, a first sensing device, a sensor and a controller, wherein: the operation room is used for accommodating animals and comprises an installation surface, and installation holes are formed in the installation surface; the first induction device comprises a first funnel and a second funnel, the bell mouth of the first funnel and the bell mouth of the second funnel are arranged on the same side, the second funnel is sleeved in the first funnel, and the bell mouth of the first funnel faces the inside of the operation chamber and is hermetically arranged in the installation hole; the medicine storage box is communicated with the inner channel of the second hopper and used for providing atomized medicines for the animals, and the medicine storage box comprises a valve which is in communication connection with the controller; the sensor is in communication connection with the controller and comprises an induction end and an emission end, the induction end and the emission end are respectively installed at two opposite ends of the bell mouth of the second funnel, and infrared rays are arranged between the emission end and the induction end; when the nose of the animal extends into the bell mouth of the second funnel, the nose of the animal blocks the propagation path of the infrared rays, and the controller controls the valve to be opened to provide the atomized medicine to the animal; when the nose of the animal leaves the bell mouth of the second funnel, the controller controls the valve to be closed to stop supplying the atomized medicine; the bell mouth department of first funnel is provided with the negative pressure for will remain the atomized medicine in the control chamber discharges the control chamber.

Optionally, the time interval between the opening of the two adjacent valves is set as t, the interval between the nose of the two adjacent animals extending into the bell mouth of the second funnel is set as t1, when t1 is less than or equal to t, the valve is closed, and when t1 is greater than t, the valve is opened.

Optionally, the medicine storage box includes a pressurization air pump, the pressurization air pump is in communication connection with the controller, and when the valve is opened, the pressurization air pump conveys the atomized medicine to the second hopper.

Optionally, animal normal position inhales medicine equipment still includes waste gas and adsorbs box, gaseous recovery pump, recovery pipe and intercommunication pipe, gaseous recovery pump with controller communication connection, the sealed intercommunication of the one end of recovering the pipe is in the afterbody of first funnel, the sealed intercommunication of the other end of recovering the pipe is in the waste gas adsorbs the box, waste gas adsorb the box with gaseous recovery pump passes through intercommunication pipe is sealed intercommunication mutually.

Optionally, the first sensing device further includes at least one support frame, and the support frame is installed between the outer side wall of the second funnel and the inner side wall of the first funnel.

Optionally, animal normal position inhales medicine equipment still includes second induction system, the structure of second induction system with first induction system's structure is the same, the mounting hole is two, first induction system with second induction system is respectively one-to-one sealed mounting two in the mounting hole, second induction system with the pump intercommunication is withdrawed to gas, so that second induction system is at its correspondence the horn mouth department of first funnel produces the negative pressure.

Optionally, the animal in-situ medicine suction device further comprises an atomized medicine generation box and a smoke concentration sensor, the smoke concentration sensor is installed in the medicine storage box, and the smoke concentration sensor is communicated with the controller; the atomizing medicine produce the case with the explosive box is linked together, the atomizing medicine produces and is provided with the electron smog spinning disk atomiser that is used for atomizing the medicine on the case, electron smog spinning disk atomiser with the controller is linked together, works as smoke concentration sensor detects in the explosive box when the concentration of atomizing medicine is less than first threshold value, controller control electron smog spinning disk atomiser opens in order to produce atomizing medicine.

Optionally, animal normal position inhales medicine equipment still includes baroceptor and relief valve, baroceptor installs in the explosive box, the explosive box still includes the connection face, the pressure release hole has been seted up on the connection face, the relief valve is sealed to be installed on the pressure release hole, the relief valve with controller communication connection works as baroceptor detects when pressure in the explosive box exceeds the second threshold value, the controller control the pressure release valve is opened, so that pressure in the explosive box reduces to be less than or equal to the second threshold value.

Optionally, animal normal position inhales medicine equipment still includes sound generator, first warning light, second warning light and cage lamp, sound generator first warning light the second warning light reaches the cage lamp is all installed in the control chamber, just first warning light is installed one side of first induction system, the second warning light is installed one side of second induction system, sound generator first warning light the second warning light reaches the cage lamp all with the controller electricity is connected.

Optionally, animal normal position inhales medicine equipment still includes the sound-proof box, the sound-proof box cover is established and is installed the control chamber first induction system reaches outside the second induction system, install the ambient noise fan on the sound-proof box.

Optionally, the control chamber still includes a plurality of electrically conductive metal poles, electrically conductive metal pole with the controller electricity is connected, and is a plurality of electrically conductive metal pole tiling is in the top of the bottom of control chamber, and with leave the clearance between the bottom of control chamber, be provided with demountable installation's collection box in the clearance, be used for collecting animal's excrement and urine.

Optionally, at least one of the first sensing device and the second sensing device is integrally formed.

The animal in-situ medicine suction equipment comprises a transparent operating room, a medicine storage box containing atomized medicines, a first sensing device, a sensor and a controller, wherein the first sensing device is hermetically mounted on a mounting surface in the operating room, the medicine storage box is communicated with an internal channel of a second funnel, animals are positioned in the operating room, when the noses of the animals stretch into a bell mouth of the second funnel, the noses of the animals block an infrared propagation path, and the controller controls a valve to be opened to provide the atomized medicines to the animals; when the nose of animal left the horn mouth of second funnel, controller control flap closed to stop providing the atomized medicine, in above-mentioned experimentation, the horn mouth department of first funnel is provided with the negative pressure all the time for will remain the atomized medicine in the control chamber and discharge the control chamber in time, thereby avoided the animal at the in-process of experiment, whole body violently leaks under the atomized medicine environment, reduced the damage of atomized medicine to the animal body, and improved the accuracy of animal to the medicine addiction experimental result.

Drawings

The objects and advantages of the present invention will be understood by the following detailed description of the preferred embodiments of the invention, taken in conjunction with the accompanying drawings, in which:

FIG. 1 is a schematic structural view of an in situ animal drug inhalation apparatus according to an embodiment of the present invention;

FIG. 2 is a first view of a first sensing device or a second sensing device of an in situ animal drug uptake apparatus according to an embodiment of the present invention;

FIG. 3 is a second view of the first sensing device or the second sensing device of the animal in situ drug delivery apparatus according to one embodiment of the present invention;

fig. 4 is a schematic structural diagram of an animal in-situ drug inhalation device according to another embodiment of the present invention.

Description of reference numerals:

1: an operation chamber; 2: a medicine storage box; 3: a first sensing device; 4: a sensor; 5: a controller; 6: a pressurized air pump; 7: an exhaust gas adsorption cartridge; 8: a gas withdrawal pump; 9: a recovery conduit; 10: a communicating conduit; 11: a mounting surface; 12: a second sensing device; 13: an atomized medicine generating chamber; 14: a smoke concentration sensor; 15: an air pressure sensor; 16: a pressure relief valve; 17: a sound generator; 18: a first warning light; 19: a second warning light; 20: a cage lamp; 21: a valve; 22: a sound insulation box; 23: a conductive metal rod; 24: an ambient noise fan; 25: an automatic smoking machine; 26: an electronic cigarette atomizer; 31: a first hopper; 32: a second hopper; 33: a flare of the first funnel; 34: a bell mouth of the second funnel; 35: a support frame; 36: a tail of the first funnel; 37: the tail part of the second funnel; 51: a transmitting end; 52: a sensing end; 53: a computer; 54: signal collection and processing software; 55: and a wireless transmission module.

Detailed Description

The present invention will be described in detail with reference to examples. In which like parts are designated by like reference numerals. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.

As shown in fig. 1 to 4, the animal in-situ drug inhalation apparatus provided by the present invention comprises a transparent operation room 1, a drug storage box 2 containing atomized drugs, a first sensing device 3, a sensor 4 and a controller 5, wherein: the operation room 1 is used for accommodating animals, the operation room 1 comprises an installation surface 11, and the installation surface 11 is provided with an installation hole; the first induction device 3 comprises a first funnel 31 and a second funnel 32, a bell mouth 33 of the first funnel and a bell mouth 34 of the second funnel are arranged on the same side, the second funnel 32 is sleeved in the first funnel 31, the bell mouth 33 of the first funnel faces the inside of the operation chamber 1, and the first funnel is hermetically arranged in the installation hole; the medicine storage box 2 is communicated with the inner channel of the second hopper 32 and used for providing atomized medicine for animals, the medicine storage box 2 comprises a valve 21, and the valve 21 is in communication connection with the controller 5; the sensor 4 is in communication connection with the controller 5, the sensor 4 comprises a sensing end and an emitting end, the sensing end and the emitting end are respectively installed at two opposite ends of the bell mouth 34 of the second funnel, and infrared rays are arranged between the emitting end and the sensing end; when the nose of the animal extends into the bell mouth 34 of the second funnel, the nose of the animal blocks the propagation path of the infrared ray, and the controller 5 controls the valve 21 to be opened to provide the atomized medicine to the animal; when the nose of the animal leaves the bell mouth 34 of the second funnel, the controller 5 controls the valve 21 to close to stop supplying the atomized medicine; a negative pressure is provided at the bell mouth 33 of the first funnel for discharging the atomized medicine remaining in the operation chamber 1 out of the operation chamber 1.

It should be noted that: the animal can be a mouse meeting experimental conditions; the operation room 1 is provided with a door which can be manually opened and closed, so that animals can be conveniently placed into the operation room 1 or taken out of the operation room 1, and the operation room 1 is made of plastic; the medicine storage box 2 is arranged in a sealed mode, and the valve 21 is communicated with the medicine storage box 2 in a sealed mode; the bell mouth 33 of the first funnel and the bell mouth 34 of the second funnel are both communicated with the operation chamber 1 in a sealing way through mounting holes, and the first sensing device 3 is detachably and hermetically mounted on the mounting surface 11 so as to facilitate the replacement of the first sensing device 3; the transmitting end constantly transmits infrared rays to the sensing end; the medicine box 2 may communicate with the tail portion 37 of the second hopper; the controller 5 can comprise a computer 53, signal collecting and processing software 54 and a wireless transmission module 55, the computer 53, the signal collecting and processing software 54 and the wireless transmission module 55 can display and record the nasal touch behaviors of the animal in the experiment and the working conditions of all elements in real time, and an animal self-administration behavior model is established through the behaviors that the animal touches and inhales atomized medicine by itself; the inner diameter of the bell mouth 34 of the second funnel is matched with the size of the nose of the animal, so that the nose of the animal can extend into the bell mouth 34 of the second funnel; preferably, the bell mouth 33 of the first funnel completely covers the bell mouth 34 of the second funnel, so as to instantaneously discharge the atomized medicine which is not inhaled by the animal and escapes to the vicinity of the bell mouth 34 of the second funnel out of the operation chamber 1 in time.

The animal in-situ medicine suction equipment provided by the invention comprises a transparent operating room 1, a medicine storage box 2 containing atomized medicines, a first sensing device 3, a sensor 4 and a controller 5, wherein the first sensing device 3 is hermetically mounted on a mounting surface 11 in the operating room 1, the medicine storage box 2 is communicated with an internal channel of a second funnel 32, animals are positioned in the operating room 1, when the noses of the animals extend into a bell mouth 34 of the second funnel, the noses of the animals block a transmission path of infrared rays, and the controller 5 controls a valve 21 to be opened to provide the atomized medicines for the animals; when the nose of the animal leaves the bell mouth 34 of the second funnel, the controller 5 controls the valve 21 to be closed to stop providing the atomized medicine, in the experimental process, the bell mouth 33 of the first funnel is always provided with negative pressure for discharging the atomized medicine remained in the operation room 1 out of the operation room 1 in time, so that the situation that the animal violently leaks to the whole body under the environment of the atomized medicine in the experimental process of the animal is avoided, the damage of the atomized medicine to the animal body is reduced, and the accuracy of the experimental result of the animal on the addiction to the medicine is improved.

In one embodiment of the present invention, the time interval between the opening of two adjacent valves 21 is set as t, the time interval between the noses of two adjacent animals extending into the bell mouth 34 of the second funnel is set as t1, when t1 is less than or equal to t, valve 21 is closed, and when t1 is greater than t, valve 21 is opened, so that the animal is prevented from excessively and continuously inhaling the atomized medicine in a short time, and the animal is prevented from causing physical injury, specifically, t may be set to 30 seconds and, when the animal's nose is inserted into the flare 34 of the second funnel two or more times within 30 seconds, although the animal's nose blocks the infrared ray propagation path two or more times, the controller 5 still controls the valve 21 to be closed, the medicine storage box 2 still does not provide atomized medicine for the animals, so that the animals are prevented from excessively and continuously inhaling the atomized medicine in a short time to cause body damage, and the use safety of the animal in-situ medicine inhaling equipment is improved.

As shown in fig. 1, the medicine tank 2 includes a pressurization air pump 6, the pressurization air pump 6 is connected in communication with the controller 5, and when the valve 21 is opened, the pressurization air pump 6 delivers the atomized medicine to the second hopper 32. In this embodiment, specifically, the controller 5 can control the pressurization air pump 6 to be opened or closed as required, and the medicine storage box 2 provides atomized medicine to the animal through the pressurization air pump 6, so that the operation convenience of the animal in-situ medicine suction device is improved.

As shown in fig. 1, the animal in-situ drug inhalation device further comprises a waste gas adsorption box 7, a gas recovery pump 8, a recovery conduit 9 and a communication conduit 10, wherein the gas recovery pump 8 is in communication connection with the controller 5, one end of the recovery conduit 9 is hermetically communicated with the tail 36 of the first funnel, the other end of the recovery conduit 9 is hermetically communicated in the waste gas adsorption box 7, and the waste gas adsorption box 7 and the gas recovery pump 8 are hermetically communicated through the communication conduit 10. It should be noted that: be provided with the material that can adsorb the atomizing medicine in the waste gas adsorbs box 7, can not inhale internal atomizing medicine with the animal and collect in waste gas adsorbs box 7, and gas is withdrawed pump 8 and can be further collected waste gas adsorption box 7 atomizing medicine that has not collected, has avoided the atomizing medicine to enter into the air, polluted environment. In this embodiment, the controller 5 controls the gas recovery pump 8 to continuously provide negative pressure to the vicinity of the bell mouth 33 of the first funnel, that is, the gas recovery pump 8 can instantly discharge the atomized medicine which is dissipated in the operation room 1 and is not inhaled into the body by the animal out of the operation room 1 in time, so as to prevent the whole body of the animal from being exposed in the atomized medicine environment, reduce the damage of the atomized medicine to the body of the animal, and improve the accuracy of the experimental result of the addiction of the animal to the medicine.

As shown in fig. 2 and 3, the first sensing device 3 further includes at least one support bracket 35, and the support bracket 35 is installed between the outer sidewall of the second funnel 32 and the inner sidewall of the first funnel 31. In this embodiment, the supporting frame 35 increases the supporting strength between the first funnel 31 and the second funnel 32, and improves the structural strength of the first sensing device 3.

As shown in fig. 1, the animal in-situ drug inhalation device further comprises a second sensing device 12, the structure of the second sensing device 12 is the same as that of the first sensing device 3, the number of the mounting holes is two, the first sensing device 3 and the second sensing device 12 are respectively and correspondingly and hermetically mounted in the two mounting holes one by one, and the second sensing device 12 is communicated with the gas recovery pump 8, so that the second sensing device 12 generates negative pressure at the corresponding bell mouth 33 of the first funnel. The second sensing device 12 is not in communication with the medicine box 2, that is, the second sensing device 12 does not contain atomized medicine. In this embodiment, the second sensing device 12 is also provided with the same negative pressure as that on the first sensing device 3 at the bell mouth 33 of the first funnel, so that when the animal is located at the first sensing device 3 or the second sensing device 12, the animal feels the same, if the animal still wants to obtain the atomized medicine through the first sensing device 3, the addiction of the animal to the atomized medicine is proved, and the accuracy of the experimental result of the addiction of the animal to the medicine in the animal in-situ medicine suction device is improved.

As shown in fig. 1, the animal in-situ medicine suction device further comprises an atomized medicine generation box 13 and a smoke concentration sensor 14, wherein the smoke concentration sensor 14 is installed in the medicine storage box 2, and the smoke concentration sensor 14 is communicated with the controller 5; atomized medicine produces case 13 and is linked together with explosive box 2, and atomized medicine produces and is provided with on the case 13 and is used for the atomizing electron smog spinning disk atomiser 26 of medicine, and electron smog spinning disk atomiser 26 is linked together with controller 5, and when smoke concentration sensor 14 detected the concentration of atomized medicine in explosive box 2 and is less than first threshold value, controller 5 control electron smog spinning disk atomiser 26 opened in order to produce atomized medicine. It should be noted that the atomized medicine generating box 13 can be replaced by an automatic smoking machine 25, and the automatic smoking machine 25 can continuously simulate a person to smoke cigarettes mouth by mouth to generate cigarette smoke and perform real animal cigarette smoke inhalation simulation. In this embodiment, the smoke concentration sensor 14 can ensure that the medicine storage box 2 can stably supply atomized medicines, so that inaccurate experimental results caused by untimely supply of atomized medicines in the medicine storage box 2 are avoided, and the accuracy of experimental results of animal addiction to medicines in animal in-situ medicine suction equipment is improved.

As shown in fig. 1, the animal in-situ medicine suction device further comprises an air pressure sensor 15 and a pressure release valve 16, the air pressure sensor 15 is installed in the medicine storage box 2, the medicine storage box 2 further comprises a connecting surface, a pressure release hole is formed in the connecting surface, the pressure release valve 16 is installed on the pressure release hole in a sealing mode, the pressure release valve 16 is in communication connection with the controller 5, when the air pressure sensor 15 detects that the pressure in the medicine storage box 2 exceeds a second threshold value, the controller 5 controls the pressure release valve 16 to be opened, so that the pressure in the medicine storage box 2 is reduced to be smaller than or equal to the second threshold value. In the embodiment, the atomized medicine with stable pressure in the medicine storage box 2 is ensured, so that the atomized medicine with stable pressure is provided for experiments, and the accuracy of experimental results of animal addiction to medicines in animal in-situ medicine suction equipment is improved.

As shown in fig. 1, the animal in-situ drug inhalation device further comprises a sound generator 17, a first prompt lamp 18, a second prompt lamp 19 and a cage lamp 20, wherein the sound generator 17, the first prompt lamp 18, the second prompt lamp 19 and the cage lamp 20 are all installed in the operation room 1, the first prompt lamp 18 is installed on one side of the first induction device 3, the second prompt lamp 19 is installed on one side of the second induction device 12, and the sound generator 17, the first prompt lamp 18, the second prompt lamp 19 and the cage lamp 20 are all electrically connected with the controller 5. It should be noted that: specifically, when the animal does not enter the operation room 1, the cage lamp 20 is set to be not on, and when the animal enters the operation room 1, the cage lamp 20 is on, so that illumination is provided for the movement of the animal; when an animal enters the operation room 1, the controller 5 controls the sound generator 17 to generate sound to remind the animal to enter the operation room 1; when the animal is located first induction system 3 one side, first warning light 18 is bright, when the animal is located second induction system 12 one side, second warning light 19 is bright to can know the position of animal in control chamber 1 more directly perceivedly, this embodiment has improved the convenient to use nature of animal normal position medicine suction device.

As shown in fig. 4, the animal in-situ inhalation apparatus further comprises a sound insulation box 22, the sound insulation box 22 is sleeved outside the operation room 1, the first sensing device 3 and the second sensing device 12, and the sound insulation box 22 is provided with an ambient noise fan 24. It should be noted that: the sound insulation board is made of a wood board, and the inner wall of the sound insulation box 22 is covered with rough EVA foam, so that external noise is isolated and adsorbed, and a dark environment is caused while sound insulation is performed; the ambient noise fan 24 can provide slight ambient white noise and ventilate. In this embodiment, the sound-proof box 22 isolates and adsorbs external noise, thereby avoiding the influence of the external noise on animals and improving the accuracy of the experimental results of the addiction of the animals to drugs in the animal in-situ drug-absorbing equipment.

As shown in fig. 1, the operation room 1 further comprises a plurality of conductive metal rods 23, the conductive metal rods 23 are electrically connected with the controller 5, the conductive metal rods 23 are tiled above the bottom of the operation room 1, a gap is reserved between the conductive metal rods and the bottom of the operation room 1, and a detachably mounted collecting box is arranged in the gap and used for collecting excrement and urine of animals, so that the convenience in use of the animal in-situ medicine suction device is improved. In the embodiment, the controller 5 energizes the conductive metal rod 23, so that current is applied to the soles of the animals, whether the drug foraging behaviors of the animals are inhibited or not is observed, and then the addiction of the animals to the drugs is judged, namely the animals expect to be electrified or want to extend the nose into the bell mouth 34 of the second funnel to obtain the atomized drugs.

In this embodiment, at least one of the first sensing device 3 and the second sensing device 12 is integrally formed, and is integrally formed, so that the number of open molds is reduced, the manufacturing process is simplified, and mass production is facilitated, and the first sensing device 3 and the second sensing device 12 may be made of glass and are integrally formed by a drawing process.

In another embodiment of the present invention, the controller 5 can be connected to and control a plurality of the above-mentioned animal in-situ drug inhalation devices at the same time, so as to realize batch training, save experimenters' time and reduce the difference between groups caused by different training times.

The experimental process provided by the invention is as follows: firstly, animals are gently placed into the laboratory operation room 1, the door of the laboratory operation room 1 is closed, the door lock catch of the sound insulation box 22 is buckled, at the moment, the cage lamp 20 is lightened, and the sound generator 17 generates buzzing sound for 2 seconds; then, when the nose of the animal extends into the bell mouth 34 of the second funnel in the first sensing device 3, the cage lamp 20 is turned off, the first indicator lamp 18 is turned on for 5 seconds to provide basic illumination and direction information, and the pressurizing air pump 6 is operated and the valve 21 is turned on to continuously supply the atomized medicine for 3 seconds. The refractory period of the system is within 30 seconds after the atomization, namely within 30 seconds after the atomization medicine is given for the first time, no matter how many times the nose of the animal extends into the bell mouth 34 of the second funnel, the valve 21 is closed, namely the atomization medicine is not provided for the animal; after the refractory period of 30 seconds, when the nose of the animal extends into the bell mouth 34 of the second funnel on the first induction device 3 again, the controller 5 controls the valve 21 to be opened, namely atomized medicine is provided for the animal; when the nose of the animal leaves the bell mouth 34 of the second funnel in the first induction device 3, the valve 21 is closed, the supply of the atomized medicine is stopped, and the processes are cycled in sequence; finally, when the administration frequency of the atomized medicine exceeds 60 times, or the experiment time exceeds 90 minutes, the experiment is ended.

It should be noted that: besides the study of in-situ drug absorption and addiction of animals, the system can also carry out the study of withdrawal after addiction and relapse after withdrawal, and the program can be adjusted only according to the experimental scheme. In addition, fixed intervals, fixed ratios, progressive ratios and other administration modes can be set through a program (training modes can be modified according to the program so as to adjust different training modes), so that further animal drug addiction research can be completed.

The animal in-situ medicine suction equipment provided by the invention comprises a transparent operating room 1, a medicine storage box 2 containing atomized medicines, a first sensing device 3, a sensor 4 and a controller 5, wherein the first sensing device 3 is hermetically mounted on a mounting surface 11 in the operating room 1, the medicine storage box 2 is communicated with an internal channel of a second funnel 32, animals are positioned in the operating room 1, when the noses of the animals extend into a bell mouth 34 of the second funnel, the noses of the animals block a transmission path of infrared rays, and the controller 5 controls a valve 21 to be opened to provide the atomized medicines for the animals; when the nose of the animal leaves the bell mouth 34 of the second funnel, the controller 5 controls the valve 21 to be closed to stop providing the atomized medicine, in the experimental process, the bell mouth 33 of the first funnel is always provided with negative pressure for discharging the atomized medicine remained in the operation room 1 out of the operation room 1 in time, so that the situation that the animal violently leaks to the whole body under the environment of the atomized medicine in the experimental process of the animal is avoided, the damage of the atomized medicine to the animal body is reduced, and the accuracy of the experimental result of the animal on the addiction to the medicine is improved.

Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.