阅读说明：本技术 一种体内病灶体积的自动测量系统及方法 (Automatic measuring system and method for focus volume in vivo ) 是由 杨军 于 2021-08-18 设计创作，主要内容包括：本发明公开一种体内病灶体积的自动测量系统,包括影像获取系统、影像差异分析系统、病灶轮廓识别系统和病灶体积测量系统,由影像获取系统获取影像并经过影像差异分析系统对病灶与正常组织的差异性识别分析,通过病灶轮廓识别系统识别出整个病灶的轮廓,进而通过病灶体积测量系统精确测量出轮廓内的病灶体积；本发明可以高效、快捷的获取病灶的体积,为临床诊断、治疗提供理论基础,适合医疗机构推广使用。(The invention discloses an automatic measuring system of focus volume in vivo, comprising an image acquisition system, an image difference analysis system, a focus contour recognition system and a focus volume measuring system, wherein the image acquisition system acquires images, the difference recognition analysis of a focus and normal tissues is carried out through the image difference analysis system, the contour of the whole focus is recognized through the focus contour recognition system, and the focus volume in the contour is accurately measured through the focus volume measuring system; the invention can efficiently and quickly acquire the volume of the focus, provides a theoretical basis for clinical diagnosis and treatment, and is suitable for popularization and use in medical institutions.)

1. An automatic measurement system for lesion volume in vivo, characterized by: the system comprises an image acquisition system, an image difference analysis system, a focus contour recognition system and a focus volume measurement system, wherein the image acquisition system acquires images, the image difference analysis system performs difference recognition analysis on focuses and normal tissues, the focus contour recognition system recognizes the contour of the whole focus, and the focus volume measurement system accurately measures the focus volume in the contour;

the image acquisition system is a medical image acquired by medical imaging equipment, and comprises images acquired by CT and MRI;

the image difference analysis system comprises a capture system, a CT value determination system and a difference analysis system, wherein the capture system comprises an input module and a tool module, and the input module selects the tool module to define a focus area on the acquired image;

the CT value measuring system measures the CT value based on the circled area, and the measuring formula of the CT value is as follows:

the value of mu can be represented by₀e^-μdIn the formula, mu and mu_ωRespectively, the test object and the water attenuation system,is a calibration factor;

the CT value measuring system measures CT values based on the defined region, the measured CT values have differences in the defined region, the difference analyzing system analyzes the differences among the measured CT values, and the focus region CT values in the defined region are obtained through comparison;

the focus contour recognition system comprises a homonymous diffusion system and a three-dimensional contour recognition system, diffusion recognition is carried out on positions of homonymous CT values in a focus area on the basis of the CT values, the diffused contours are recognized by the three-dimensional contour recognition system after the diffusion is finished, and edge detection and contour extraction are carried out by the three-dimensional contour recognition system;

the lesion volume measurement system performs volume measurement through a three-dimensional contour acquired by the lesion contour recognition system, and the volume measurement is automatically measured by the lesion volume measurement system.

2. The system for automated in vivo lesion volume measurement according to claim 1, wherein: the focus contour recognition system fills and marks focus areas through different colors on the basis of CT values, and completely fills and marks the areas with the same CT value according to the same CT value principle.

3. The automated lesion volume measurement method of the automated in vivo lesion volume-based measurement system according to any one of claims 1 to 2, wherein:

the automatic in vivo lesion volume measuring method comprises the following steps:

step 1, acquiring an imaging image

Acquiring medical images through CT and MRI, and leading the acquired medical images into a system;

step 2, analyzing the difference of the images of the delineating area

After the medical image acquired in the step 1 is imported into the system, an operator can select a tool module by using an input module to define a region of a suspected focus on the acquired image, a CT value determination system performs CT value determination based on the defined region, the CT values in the region are inevitably different due to the fact that the defined region is manually operated, and a difference analysis system acquires the CT value of the focus region in the defined region by comparison to finally determine the CT value of the focus region;

step 3. identification of focus contour

After the focus area CT value is determined, performing diffusion identification on the position of the focus area with the CT value, wherein the principle is that filling identification is performed on the position area with the same CT value by different colors, and after filling is completed, a three-dimensional contour identification system identifies and scans the filled focus contour by edge detection and contour extraction;

step 4. automatic measurement of lesion volume

And performing calculation measurement on the volume of the focus by a focus volume measurement system on the focus contour identified based on the three-dimensional contour.

4. A method for automated in vivo lesion volume measurement as defined in claim 3, wherein: and 2, analyzing the difference of the CT values in the region, namely determining the CT value of the region different from the normal tissue as a lesion region by comparing the CT values of the normal tissue.

5. A method for automated in vivo lesion volume measurement as defined in claim 3, wherein: in the automatic in-vivo lesion volume measuring method, if the CT value of the lesion area obtained in the step 2 is not different or is the same as that of a normal tissue, the whole measuring process is finished.

Technical Field

The invention relates to the technical field of focus volume measurement, in particular to an automatic measurement system and method for focus volume in vivo.

Background

The focus is the diseased part of the body. For example, a certain portion of the lung is destroyed by tubercle bacillus, and this portion is the focus of tuberculosis. A limited diseased tissue with pathogenic microorganisms is called a lesion. Besides the lesions themselves in the human body, they often cause diseases of distant organs.

The measurement of the focus volume has great significance for the health examination of patients and the later diagnosis and treatment, relates to the center of gravity of the whole diagnosis and treatment, and utilizes the three-dimensional image to analyze the three-dimensional shape of the internal structure of the organ along with the development of the medical imaging technology so as to analyze and judge whether diseases exist in the organ and become an auxiliary means for disease diagnosis; that is, the CT technology in the existing imaging technology is used to realize the estimation and measurement of the lesion volume, but there are many defects, such as the difference of CT values generally reflected by the lesion parameters obtained by CT diagnosis, but the lesion volume cannot be obtained quickly in the existing technology.

In summary, the prior art has the following disadvantages: at present, a system and a method for quickly and accurately measuring the volume of a focus in a body are lacked, so that the diagnosis of imaging and subsequent clinical treatment are influenced.

Disclosure of Invention

Aiming at the problems in the prior art, the invention provides an automatic measuring system and method for the volume of a focus in vivo, which are used for obtaining a focus outline by analyzing the difference degree of image parameters of a defined position and automatically calculating and measuring the volume of the focus.

In order to achieve the technical purpose and achieve the technical effect, the invention is realized by the following technical scheme:

an automatic measuring system for the volume of a focus in vivo comprises an image acquisition system, an image difference analysis system, a focus contour recognition system and a focus volume measuring system, wherein the image acquisition system acquires an image, the image difference analysis system performs difference recognition analysis on the focus and normal tissues, the focus contour recognition system recognizes the contour of the whole focus, and the focus volume measuring system accurately measures the focus volume in the contour;

the medical image acquired by the image acquisition system for medical imaging equipment is original data acquired by CT, and the original data is CT volume data, namely a cross-axis position thin-layer image;

the image difference analysis system comprises a capture system, a CT value determination system and a difference analysis system, wherein the capture system comprises an input module and a tool module, and the input module selects the tool module to define a focus area on the acquired image;

the CT value measuring system measures the CT value based on the circled area, and the measuring formula of the CT value is as follows:

the value of mu can be represented by₀e^-μdIn the formula, mu and mu_ωRespectively, the test object and the water attenuation system,is a calibration factor;

the CT value measuring system measures CT values based on the defined region, the measured CT values have differences in the defined region, the difference analyzing system analyzes the differences among the measured CT values, and the focus region CT values in the defined region are obtained through comparison;

the focus contour recognition system comprises a homonymous diffusion system and a three-dimensional contour recognition system, diffusion recognition is carried out on positions of homonymous CT values in a focus area on the basis of the CT values, the diffused contours are recognized by the three-dimensional contour recognition system after the diffusion is finished, and edge detection and contour extraction are carried out by the three-dimensional contour recognition system;

the focus volume measurement system performs volume measurement through a three-dimensional profile acquired by the focus profile recognition system, and the volume measurement is automatically measured by the focus volume measurement system;

furthermore, the lesion contour recognition system fills and marks lesion regions by different colors on the basis of the CT value, and completely fills and marks the regions with the same CT value according to the same CT value principle.

Furthermore, the focus area of the image difference analysis system is defined as a region in which an area of interest is delineated on a horizontal axis position or a reconstructed coronal position or a reconstructed sagittal position to automatically and quickly measure the volume of the focus.

Another object of the present invention is to provide an automatic lesion volume measuring method based on an automatic in vivo lesion volume measuring system;

the automatic in vivo lesion volume measuring method comprises the following steps:

step 1, acquiring an imaging image

Acquiring medical images through CT and MRI, and leading the acquired medical images into a system;

step 2, analyzing the difference of the images of the delineating area

After the medical image acquired in the step 1 is imported into the system, an operator can select a tool module by using an input module to define a region of a suspected focus on the acquired image, a CT value determination system performs CT value determination based on the defined region, the CT values in the region are inevitably different due to the fact that the defined region is manually operated, and a difference analysis system acquires the CT value of the focus region in the defined region by comparison to finally determine the CT value of the focus region;

step 3. identification of focus contour

After the focus area CT value is determined, performing diffusion identification on the position of the focus area with the CT value, wherein the principle is that filling identification is performed on the position area with the same CT value by different colors, and after filling is completed, a three-dimensional contour identification system identifies and scans the filled focus contour by edge detection and contour extraction;

step 4. automatic measurement of lesion volume

And performing calculation measurement on the volume of the focus by a focus volume measurement system on the focus contour identified based on the three-dimensional contour.

Further, the step 2 analyzes the difference of the CT values in the region by comparing the CT values of the normal tissue and determining the CT value measured in the region different from the normal tissue as the lesion region.

Further, in the automatic in vivo lesion volume measuring method, if there is no difference or the CT value of the lesion region obtained in step 2 is the same as that of the normal tissue, the whole measuring process is finished.

The invention has the beneficial effects that: the invention relates to an automatic measuring system and a method for the volume of a focus in vivo, which obtains a focus outline by analyzing the image parameter difference degree of a delineation position, automatically calculates and measures the volume of the focus, artificially selects a suspected focus position to delineate a region, then identifies and analyzes the difference between the focus and normal tissues by an image difference analysis system, identifies the outline of the whole focus by a focus outline identification system, and further accurately measures the focus volume in the outline by a focus volume measurement system; the device can efficiently and quickly acquire the volume of the focus, simplify the measurement method, reduce the clinical workload, improve the working efficiency, provide a theoretical basis for clinical diagnosis and treatment, and is suitable for popularization and use in medical institutions.

Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic diagram of an automatic in vivo lesion volume measurement system according to an embodiment of the present invention;

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

As shown in fig. 1

An automatic measuring system for the volume of a focus in vivo comprises an image acquisition system, an image difference analysis system, a focus contour recognition system and a focus volume measuring system, wherein the image acquisition system acquires an image, the image difference analysis system performs difference recognition analysis on the focus and normal tissues, the focus contour recognition system recognizes the contour of the whole focus, and the focus volume measuring system accurately measures the focus volume in the contour;

the image acquisition system is a medical image acquired by medical imaging equipment, and comprises images acquired by CT and MRI;

the image difference analysis system comprises a capture system, a CT value determination system and a difference analysis system, wherein the capture system comprises an input module and a tool module, and the input module selects the tool module to define a focus area on the acquired image;

the CT value measuring system measures the CT value based on the circled area, and the measuring formula of the CT value is as follows:

the value of mu can be represented by₀e^-μdIn the formula, mu and mu_ωRespectively, the test object and the water attenuation system,is a calibration factor;

the CT value measuring system measures CT values based on the defined region, the measured CT values have differences in the defined region, the difference analyzing system analyzes the differences among the measured CT values, and the focus region CT values in the defined region are obtained through comparison;

the focus contour recognition system comprises a homonymous diffusion system and a three-dimensional contour recognition system, diffusion recognition is carried out on positions of homonymous CT values in a focus area on the basis of the CT values, the diffused contours are recognized by the three-dimensional contour recognition system after the diffusion is finished, and edge detection and contour extraction are carried out by the three-dimensional contour recognition system;

the lesion volume measurement system performs volume measurement through a three-dimensional contour acquired by the lesion contour recognition system, and the volume measurement is automatically measured by the lesion volume measurement system.

Examples

The automatic in vivo lesion volume measuring method comprises the following steps:

step 1, acquiring an imaging image

The medical image is acquired through CT and MRI, the acquired medical image is guided into the system, and the acquired medical image is acquired through CT and MRI scanning, so that each parameter of the medical image can be accurately acquired;

step 2, analyzing the difference of the images of the delineating area

After the medical image acquired in the step 1 is imported into the system, an operator can select a tool module by using an input module to define a region of a suspected focus on the acquired image, a CT value determination system performs CT value determination based on the defined region, the CT values in the region are inevitably different due to the fact that the defined region is manually operated, and a difference analysis system acquires the CT value of the focus region in the defined region by comparison to finally determine the CT value of the focus region;

analyzing the difference of the CT values in the region, namely, determining the CT value of the region different from the normal tissue as a focus region by comparing the CT value of the normal tissue;

if there is no difference or the CT value is the same as that of the normal tissue, the whole measuring process is finished.

For the delineation of the whole delineation area, the delineation can be carried out by a square or round module according to the module, the delineation mode can be that a reference point is designated, the reference point determines the post-stretching, the stretching direction is four directions, namely front, back, left and right, and the calculation of the next step is started when the operation is not carried out for 3 seconds after the delineation area is selected;

the CT value measuring system measures the CT value based on the circled area, and the measuring formula of the CT value is as follows:

the value of mu can be represented by₀e^-μdIn the formula, mu and mu_ωRespectively, the test object and the water attenuation system,is a calibration factor;

the CT values in the circled area are calculated, and are different inevitably because the selection process is the rough operation, different CT values are displayed respectively when the CT values are calculated, and the CT values of the focus tissues can be obtained by filtering the CT values of the normal tissues after the comparison through the comparison of the CT values;

step 3. identification of focus contour

After the focus area CT value is determined, performing diffusion identification on the position of the focus area with the CT value, wherein the principle is that filling identification is performed on the position area with the same CT value by different colors, and after filling is completed, a three-dimensional contour identification system identifies and scans the filled focus contour by edge detection and contour extraction;

based on filling diffusion marks with the same CT value, the three-dimensional marking is carried out based on medical images in the marking process through a software algorithm of a computer, then edge detection and contour extraction are carried out through a three-dimensional contour recognition system, and a filled three-dimensional focus volume model is obtained after extraction;

step 4. automatic measurement of lesion volume

Calculating and measuring the volume of the focus by a focus volume measuring system on the basis of the focus contour identified by the three-dimensional contour;

calculating the volume of the irregular focus, and automatically generating by computer software;

for the above steps, if the computed CT values within the delineated region are consistent, there are generally two cases: the focus delineating is incomplete or no focus area, and for the situation, the calculation is finished;

of course, the above calculation process is not one-time calculation, and may be calculated after regions of different specifications are defined, and finally an average value is calculated to obtain a volume value of the lesion volume model and the volume value of the volume model.

The technical scheme of the invention is quick to operate, and an operator can calculate and compare the suspected lesion area on the medical image by the system to further obtain a lesion volume model and a numerical value, so that the system is suitable for popularization and use in medical institutions.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.