阅读说明：本技术 一种含螺虫乙酯和甲维盐的农药组合物 (Pesticide composition containing spirotetramat and emamectin benzoate ) 是由 尚庆利 潘怡欧 刘雪梅 杨凤婷 于 2021-09-16 设计创作，主要内容包括：一种含螺虫乙酯和甲维盐的农药组合物属农药及应用技术领域,本发明由活性成分螺虫乙酯和甲维盐二元复配,螺虫乙酯和甲维盐的质量比为1:9～49,优选质量比为1:19～29；所述农药组合物的剂型为悬浮剂和水分散粒剂；本发明具有明显的增效作用,能减少杀虫剂的用量,降低生产成本和使用成本,还能延缓害虫抗药性的产生,可用于抗性害虫的综合治理。(A pesticide composition containing spirotetramat and emamectin benzoate belongs to the technical field of pesticides and application, and is prepared by compounding active ingredients spirotetramat and emamectin benzoate in a binary manner, wherein the mass ratio of the spirotetramat to the emamectin benzoate is 1: 9-49, and the preferable mass ratio is 1: 19-29; the pesticide composition is in the dosage forms of a suspending agent and water dispersible granules; the invention has obvious synergistic effect, can reduce the dosage of the pesticide, reduce the production cost and the use cost, can delay the generation of the drug resistance of pests, and can be used for the comprehensive treatment of resistant pests.)

1. A pesticide composition containing spirotetramat and emamectin benzoate is characterized in that: the pesticide composition is prepared by binary compounding of active ingredients of spirotetramat and emamectin benzoate, wherein the mass ratio of the spirotetramat to the emamectin benzoate is 1: 9-49, and the preferable mass ratio is 1: 19-29.

2. The pesticide composition containing spirotetramat and emamectin benzoate according to claim 1, which is characterized in that: the pesticide composition is in the dosage forms of a suspending agent and water dispersible granules.

3. The pesticide composition containing the spirotetramat and the emamectin benzoate according to claim 2, wherein when the pesticide composition is a suspending agent, the pesticide composition comprises the following components in percentage by weight: 3% of spirotetramat, 57-87% of emamectin benzoate, 8-10% of polyoxyethylene polyoxypropylene block copolymer, 3-5% of nekal, 1.5-2% of carboxymethyl cellulose, 0.3-0.5% of potassium sorbate, 0.1% of silicone oil, 2.5-3% of ethylene glycol and 20-25% of deionized water.

4. The pesticide composition containing the spirotetramat and the emamectin benzoate according to claim 2, wherein when the pesticide composition is in the form of water dispersible granules, the pesticide composition comprises the following components in percentage by weight: 3% of spirotetramat, 57-87% of emamectin benzoate, 3-5% of sodium methylene dinaphthalene sulfonate, 7-10% of maleic acid-acrylic acid copolymer salt, 5-8% of alkyl succinate sulfonic acid sodium salt, 5% of bentonite and 18-20% of diatomite.

5. Use of a pesticidal composition comprising spirotetramat and an emamectin benzoate according to claim 1 for the control of crop pests from the orders hemiptera, lepidoptera, coleoptera, thysanoptera and diptera.

Technical Field

The invention belongs to the technical field of pesticides and application, and particularly relates to a pesticide composition containing spirotetramat and emamectin benzoate, which is mainly applied to prevention and treatment of piercing-sucking pests such as cotton aphids and the like on crops.

Background

The pesticide combination strategy is based on the fact that: if the possibility of resistance to one of the two insecticides is a rare and independent event, then the possibility of simultaneous resistance to both insecticides in the mixture is extremely low. The combined application of insecticides with different action mechanisms is one of the important means for controlling and delaying the drug resistance of pests.

Spirotetramat (spirotetramat), which is a tetronic acid compound, is one of modern insecticides with bidirectional systemic conductivity so far. The compound can move upwards and downwards in the whole plant body to reach leaf surfaces and barks, so that the compound can prevent and control pests on inner leaves of lettuce and Chinese cabbage and fruit tree barks. This unique systemic property protects the nascent stems, leaves and roots from the growth of pest eggs and larvae. The spirotetramat has long lasting period and can provide effective control for 8 weeks. The spirotetramat has high efficiency and broad spectrum, and can effectively prevent and control various sucking mouthparts pests, such as aphids, thrips, psyllids, mealybugs, whiteflies, scale insects and the like.

The Emamectin Benzoate (also called Emamectin Benzoate) has extremely high activity on lepidoptera insect larvae and other pests, has both stomach toxicity and contact poisoning effects, does not harm beneficial insects in the process of controlling the pests, is beneficial to the comprehensive control of the pests, expands the insecticidal spectrum and reduces the toxicity to people and livestock. Considering that the pesticide is an environment-friendly low-toxicity pesticide, the pesticide is used for preventing and treating more insect pests on industrial crops such as tobacco, tea, cotton and the like and all vegetable crops in China at present. Is easily degraded under the influence of factors such as over-high or over-low environmental acidity, illumination and the like.

Disclosure of Invention

The spirotetramat has good effect and application prospect in the aspect of preventing and controlling piercing-sucking pests such as cotton aphids and the like. However, in view of the rapid development of the resistance of field cotton aphids to spirotetramat and the high sale price of spirotetramat in the market, in order to solve the problem of drug resistance of cotton aphids, we intend to compound other pesticide compounds for preventing and treating piercing-sucking mouthpart pests with lower cost with spirotetramat to provide a pesticide composition containing a small amount of spirotetramat.

The pesticide composition containing the spirotetramat and the emamectin benzoate is prepared by compounding the active ingredients spirotetramat and emamectin benzoate in a binary manner, wherein the mass ratio of the spirotetramat to the emamectin benzoate is 1: 9-49, and the preferable mass ratio is 1: 19-29.

The pesticide composition is in the dosage forms of a suspending agent and water dispersible granules.

When the pesticide composition is a suspending agent, the components in percentage by weight are as follows: 3% of spirotetramat, 57-87% of emamectin benzoate, 8-10% of polyoxyethylene polyoxypropylene block copolymer, 3-5% of nekal, 1.5-2% of carboxymethyl cellulose, 0.3-0.5% of potassium sorbate, 0.1% of silicone oil, 2.5-3% of ethylene glycol and 20-25% of deionized water; the suspending agent comprises the following specific production steps: mixing other auxiliary agents, uniformly mixing by high-speed shearing, adding the spirotetramat and emamectin benzoate as effective components, and sanding for 3 hours in a sand mill of 2000r/min to ensure that the particle size is below 5mm, thus preparing the suspending agent of the composition.

When the pesticide composition is in the form of water dispersible granules, the pesticide composition comprises the following components in percentage by weight: 3% of spirotetramat, 57-87% of emamectin benzoate, 3-5% of sodium methylene dinaphthalene sulfonate, 7-10% of maleic acid-acrylic acid copolymer salt, 5-8% of alkyl succinate sulfonic acid sodium salt, 5% of bentonite and 18-20% of diatomite; the water dispersible granule comprises the following specific production steps: according to the formula, the spirotetramat, the emamectin benzoate, the dispersant, the wetting agent, the disintegrant and the filler are uniformly mixed, the mixture is crushed by an ultramicro jet mill, the wettable powder and a certain amount of water (a binder is dissolved in water in advance) are mixed after being crushed, the mixture is kneaded in a kneading machine to prepare a plastic material, and finally the plastic material is sent into an extrusion granulator for granulation, and the water dispersible granule of the composition is obtained through drying and screening.

The pesticide composition containing the spirotetramat and the emamectin benzoate can be applied to the prevention and control of crop pests, wherein the crop pests are hemiptera, lepidoptera, coleopteran, thysanoptera and diptera pests, such as diaphorina citri, brown planthopper, laodelphax striatellus, bemisia tabaci, wheat aphid, cotton aphid, green peach aphid, celery aphid, mealybug, citrus mealybug, diamond back moth, cotton bollworm, tobacco budworm, armyworm, asparagus caterpillar, spodoptera exigua, cabbage looper, cabbage caterpillar, rice stem borer, rice leaf roller, corn borer, leaf roller moths, carpophagus, potato beetle, thrips and the like.

The pesticide of the invention relates to a solvent, a dispersant, a wetting agent, a disintegrating agent, a thickening agent, an antifreezing agent, a defoaming agent and a filler in the production process, wherein:

the solvent is as follows: toluene, xylene, biodiesel, diesel oil, methanol, ethanol, n-butanol, isopropanol, turpentine, dimethylformamide, dimethyl sulfoxide, water and other solvents.

The dispersant is as follows: sodium lignosulfonate, calcium lignosulfonate, sodium naphthalenesulfonate formaldehyde condensate (NNO), laureth, dioctyl sodium sulfosuccinate, alkylphenol ethoxylates, polyoxyethylene polyoxypropylene ether block copolymer, alkylphenol polyoxyethylene phosphate, CMC, sodium dibutylnaphthalene sulfonate, dodecylpolyoxyethylene ether phosphate, sodium polycarboxylate, polyarylphenol polyoxyethylene ether phosphate, polyvinyl alcohol, gum arabic, nekal BX (5, 6-dibutylnaphthalene-2-sulfonate), sodium methyl aminoethyl oleate, and the like, and may be one or a mixture of more.

The wetting agent is: sodium dodecyl benzene sulfonate, pesticide emulsion 2000 series, Span20, tween 60, alkylphenol polyoxyethylene, alkylaryl sulfonate, nekal, sodium dodecyl benzene sulfate, potassium oleate, dioctyl sodium sulfosuccinate, alkyl polyoxyethylene ether sulfonate, pesticide emulsion 100, pesticide emulsion 600, sorbitol polyoxyethylene ether, sodium diisooctyl succinate, etc., which can be one or a mixture of more.

The disintegrating agent is: urea, bentonite, citric acid, succinic acid, ammonium sulfate, sodium chloride, calcium and aluminum chloride, etc., and may be one or a mixture of more.

The thickening agent is selected from: xanthan gum, heteropolysaccharide, sodium carboxymethylcellulose, polyvinyl alcohol, gelatin, agar, soluble starch and its derivatives, polyacrylate, natural polysaccharide, magnesium aluminum silicate, methylcellulose, alginic acid, silicic acid, etc., and can be one or more mixture.

The stabilizer is as follows: alkyl phosphate and alkoxide thereof, polyvinyl alcohol, potassium phosphate, bentonite, light calcium carbonate, white carbon black, diatomite, perlite powder, aryl phosphate, phosphite ester, polyol, alkyl sulfonate and substituted ammonium salt thereof, substituted epoxide and the like, and can be one or a mixture of more.

The antifreezing agent is: ethylene glycol, propylene glycol, glycerin, sucrose, polyethylene glycol, polyvinylpyrrolidone, urea, ammonium sulfate, calcium chloride, sodium chloride, etc., and may be a mixture of one or more.

The defoaming agent can be: ethoxylated polymers of glycerol, silicic acids, C8-C10 fatty alcohols, lauric acid, palmitic acid, stearic acid, sulfonamides, and the like.

The filler is as follows: one or more of kaolin, diatomite, argil, bentonite, montmorillonite, attapulgite, peat, white carbon black, starch and light calcium carbonate.

The compound pesticide taking the spirotetramat and the emamectin benzoate as the active ingredients has obvious synergistic effect, reduces the dosage of the pesticide, reduces the production cost and the use cost, can delay the generation of drug resistance of pests, and can be used for comprehensive treatment of resistant pests.

Detailed Description

The pesticide composition containing the spirotetramat and the emamectin benzoate is prepared by compounding the active ingredients spirotetramat and emamectin benzoate in a binary manner, wherein the mass ratio of the spirotetramat to the emamectin benzoate is 1: 9-49, and the preferable mass ratio is 1: 19-29.

The pesticide composition is in the dosage forms of a suspending agent and water dispersible granules.

When the pesticide composition is a suspending agent, the components in percentage by weight are as follows: 3% of spirotetramat, 57-87% of emamectin benzoate, 8-10% of polyoxyethylene polyoxypropylene block copolymer, 3-5% of nekal, 1.5-2% of carboxymethyl cellulose, 0.3-0.5% of potassium sorbate, 0.1% of silicone oil, 2.5-3% of ethylene glycol and 20-25% of deionized water.

When the pesticide composition is in the form of water dispersible granules, the pesticide composition comprises the following components in percentage by weight: 3% of spirotetramat, 57-87% of emamectin benzoate, 3-5% of sodium methylene dinaphthalene sulfonate, 7-10% of maleic acid-acrylic acid copolymer salt, 5-8% of alkyl succinate sulfonic acid sodium salt, 5% of bentonite and 18-20% of diatomite.

The pesticide composition containing the spirotetramat and the emamectin benzoate can be applied to the prevention and control of crop pests, wherein the crop pests are hemiptera, lepidoptera, coleopteran, thysanoptera and diptera pests, such as diaphorina citri, brown planthopper, laodelphax striatellus, bemisia tabaci, wheat aphid, cotton aphid, green peach aphid, celery aphid, mealybug, citrus mealybug, diamond back moth, cotton bollworm, tobacco budworm, armyworm, asparagus caterpillar, spodoptera exigua, cabbage looper, cabbage caterpillar, rice stem borer, rice leaf roller, corn borer, leaf roller moths, carpophagus, potato beetle, thrips and the like.

Example (b): the spirotetramat and emamectin benzoate have different proportions and have combined toxicity on cotton aphids.

The test takes cotton aphids as test objects, adopts a leaf pesticide film method, and comprises the following specific steps:

preparing acetone for the pesticide raw material into 1% mother liquor, diluting the mother liquor with acetone, preparing liquid medicines with series concentrations by using 0.1% (v/v) Triton X-100 solution, repeating each concentration for 3 times, and performing 3 groups of experiments by using distilled water containing 0.1% (v/v) Triton X-100 solution as a control. Selecting healthy cotton seedlings, soaking the cotton seedlings in each liquid medicine to be detected for 30s, taking out the cotton seedlings, airing the cotton seedlings, fixing the aired cotton seedlings on seedling supports, and soaking roots of the cotton seedlings in clean water. Selecting wingless adult aphids, gently picking the adult aphids on leaves by using a small writing brush, covering the leaves by using about 25 leaves, and then putting the leaves into an insect breeding room for culture. The death of the test insects is detected after a certain period of time (7 days for spirotetramat and 3 days for emamectin benzoate)The condition (the condition that the patient can not normally move is regarded as death), SPSS19.0 is used for counting and analyzing the experimental data to obtain a virulence regression equation and LC₅₀Values and 95% confidence limits, etc.

The co-toxicity coefficient (CTC value) of the mixture is calculated by adopting the Sun Yunpei method. The co-toxicity coefficient CTC is calculated as follows: (spirotetramat is used as a standard medicament, and the virulence index of the spirotetramat is 100);

toxicity Index (TI) of emamectin benzoate-spirotetramat LC 50/emamectin benzoate LC50 x 100

True virulence index (ATI) of M-LC 50X 100 of spirotetramat LC50/M

M theoretical virulence index (TTI) Tsaxatilis and Tsaxatilis

The cotoxicity coefficient (CTC) of M is M, i.e., TTI × 100 of ATI/M in formula:

m is a mixture of spirotetramat and emamectin benzoate in different proportions

The spirotetramat P is the proportion of spirotetramat in the mixture

The emamectin benzoate is the proportion of emamectin benzoate in the mixture.

Virulence assay results are shown in table 1:

TABLE 1 toxicity and Co-toxicity coefficients of spirotetramat and emamectin benzoate on Aphis gossypii (SR) strains

The results in table 1 show that: when the mass ratio of the spirotetramat to the emamectin benzoate is 1: 9-49, the co-toxicity coefficients are all larger than 120, obvious synergistic effects are shown, and particularly when the mass ratio of the spirotetramat to the emamectin benzoate is 1:19, the co-toxicity coefficient is 136.520 which is the largest, and the prevention and treatment effect is obviously improved. The experimental result shows that the compounding of the spirotetramat and the emamectin benzoate has obvious synergistic effect on the cotton aphids.