阅读说明：本技术 一种隐形眼镜护理液及其制备方法 (Contact lens care solution and preparation method thereof ) 是由 霍俊霏 吕本松 于 2021-10-26 设计创作，主要内容包括：本发明提供了一种隐形眼镜护理液及其制备方法,所述护理液包括按重量份数计的如下组分：氯化钠1～5份、磷酸二氢钠2～10份、牛磺酸1～3份、EDTA-2Na 1～3份、保湿剂0.1～0.5份、清洁剂0.1～2份、聚六亚甲基双胍盐酸盐0.5～3份、薄荷醇0.1～0.5份、中药提取物1～5份、纯化水100～120份。本发明所述的隐形眼镜护理液在保证清洁效果良好的同时具有良好的保湿、抑菌效果,可有效缓解长期佩戴时眼部发炎发痒的情况。(The invention provides a contact lens care solution and a preparation method thereof, wherein the care solution comprises the following components in parts by weight: 1-5 parts of sodium chloride, 2-10 parts of sodium dihydrogen phosphate, 1-3 parts of taurine, 1-3 parts of EDTA-2Na, 0.1-0.5 part of humectant, 0.1-2 parts of detergent, 0.5-3 parts of polyhexamethylene biguanide hydrochloride, 0.1-0.5 part of menthol, 1-5 parts of traditional Chinese medicine extract and 100-120 parts of purified water. The contact lens care solution has good moisturizing and antibacterial effects while ensuring good cleaning effect, and can effectively relieve the situation that eyes are inflamed and itchy when the contact lens care solution is worn for a long time.)

1. The contact lens care solution is characterized by comprising the following components in parts by weight: 1-5 parts of sodium chloride, 2-10 parts of sodium dihydrogen phosphate, 1-3 parts of taurine, 1-3 parts of EDTA-2Na, 0.1-0.5 part of humectant, 0.1-2 parts of detergent, 0.5-3 parts of polyhexamethylene biguanide hydrochloride, 0.1-0.5 part of menthol, 1-5 parts of traditional Chinese medicine extract and 100-120 parts of purified water.

2. The contact lens care solution according to claim 1, wherein: the humectant comprises the following components in parts by weight: 0.1-0.2 part of glycerin and 0.1-0.3 part of sodium hyaluronate.

3. The contact lens care solution according to claim 1, wherein: the detergent comprises the following components in parts by weight: 4070.1-1 parts of poloxamer and 0.1-1 part of sodium citrate.

4. The contact lens care solution according to claim 1, wherein: the traditional Chinese medicine extract comprises the following components in parts by weight: 0.5-2 parts of radix scutellariae extract and 0.5-3 parts of coptis chinensis extract.

5. A method for producing a contact lens care solution according to claim 1, characterized in that: the method comprises the following steps:

s1, weighing sodium chloride, sodium dihydrogen phosphate, taurine, EDTA-2Na, humectant, cleanser, polyhexamethylene biguanide hydrochloride, menthol, traditional Chinese medicine extract and purified water according to the proportion;

s2, dissolving sodium chloride, sodium dihydrogen phosphate, taurine, EDTA-2Na, a humectant, a cleaning agent, polyhexamethylene biguanide hydrochloride and menthol in partially purified water to obtain a solution A;

s3, dissolving the traditional Chinese medicine extract in the residual purified water to obtain a solution B;

s4, uniformly mixing the solution A and the solution B, adjusting the pH value to 6.5-7.5, and adjusting the osmotic pressure to 270-320 mOsm/kg. H₂O；

And S5, filtering the solution obtained in the step S4 through a 0.1-5 micron filter, and sterilizing to obtain the contact lens care solution.

6. The method for preparing a contact lens care solution according to claim 5, wherein: the traditional Chinese medicine extract in the S3 is radix scutellariae extract and rhizoma coptidis extract.

7. The method for preparing a contact lens care solution according to claim 6, wherein: the radix scutellariae extract is obtained by the following method: cleaning the radix scutellariae, soaking the radix scutellariae in clear water, heating and decocting the radix scutellariae in clear water for 30-60 min, concentrating the radix scutellariae, and filtering the radix scutellariae to obtain filtrate, namely the radix scutellariae extract; the Coptidis rhizoma extract is obtained in the same manner.

Technical Field

The invention belongs to the technical field of contact lens care, and particularly relates to a contact lens care solution and a preparation method thereof.

Background

The contact lens care solution mainly comprises sodium chloride and a preservative, and is used for cleaning and disinfecting biological materials, taking out protein and the like. Contact lenses can be contaminated with secretions in the eye during wear, and accumulation of secretions after extended wear can cause discomfort to the wearer's eye. The contact lenses can be cleaned by the lens care solution, so that the cleanness of the contact lenses is ensured, and the safety and the comfort of wearing next time are improved. The existing contact lens care solution mainly focuses on the sterilization and disinfection of lenses, and has poor efficacy on relieving eye dryness and itching caused by long-term wearing.

Disclosure of Invention

In view of the above, the present invention provides a contact lens care solution with good moisturizing effect, antibacterial effect and anti-inflammatory and anti-itching effect while ensuring good cleaning effect, and a preparation method thereof, so as to solve the above problems.

In order to achieve the purpose, the technical scheme of the invention is realized as follows:

the invention provides a contact lens care solution which comprises the following components in parts by weight: 1-5 parts of sodium chloride, 2-10 parts of sodium dihydrogen phosphate, 1-3 parts of taurine, 1-3 parts of EDTA-2Na, 0.1-0.5 part of humectant, 0.1-2 parts of detergent, 0.5-3 parts of polyhexamethylene biguanide hydrochloride, 0.1-0.5 part of menthol, 1-5 parts of traditional Chinese medicine extract and 100-120 parts of purified water.

Further, the humectant comprises the following components in parts by weight: 0.1-0.2 part of glycerin and 0.1-0.3 part of sodium hyaluronate.

Further, the cleaning agent comprises the following components in parts by weight: 4070.1-1 parts of poloxamer and 0.1-1 part of sodium citrate.

Further, the traditional Chinese medicine extract comprises the following components in parts by weight: 0.5-2 parts of radix scutellariae extract and 0.5-3 parts of coptis chinensis extract.

In the contact lens care solution: sodium chloride is an osmotic pressure regulator and plays a role in regulating osmotic pressure; sodium dihydrogen phosphate is used as a buffering agent; taurine is a sulfur-containing amino acid, has the functions of diminishing inflammation, relieving pain and resisting bacteria, can effectively promote the normal development of retina and improve the immunologic function; EDTA-2Na is a chelating agent; the glycerin and the sodium hyaluronate have good moisturizing and anti-drying effects; poloxamer 407 and sodium citrate are used as cleaning agents to clean the proteins on the lenses; the polyhexamethylene biguanide hydrochloride has good bactericidal effect; menthol has the effects of refreshing and relieving itching; the radix scutellariae and the rhizoma coptidis have the functions of bacteriostasis and inflammation diminishing, and can effectively relieve the itching of eyes.

The invention also provides a preparation method of the contact lens care solution, which comprises the following steps:

s1, weighing sodium chloride, sodium dihydrogen phosphate, taurine, EDTA-2Na, humectant, cleanser, polyhexamethylene biguanide hydrochloride, menthol, traditional Chinese medicine extract and purified water according to the proportion;

s2, dissolving sodium chloride, sodium dihydrogen phosphate, taurine, EDTA-2Na, a humectant, a cleaning agent, polyhexamethylene biguanide hydrochloride and menthol in partially purified water to obtain a solution A;

s3, dissolving the traditional Chinese medicine extract in the residual purified water to obtain a solution B;

s4, uniformly mixing the solution A and the solution B, adjusting the pH value to 6.5-7.5, and adjusting the osmotic pressure to 270-320 mOsm/kg. H₂O；

And S5, filtering the solution obtained in the step S4 through a 0.1-5 micron filter, and sterilizing to obtain the contact lens care solution.

Further, the Chinese medicinal extracts in the S3 are radix scutellariae extract and rhizoma coptidis extract.

Further, the radix scutellariae extract is obtained by the following method: cleaning the scutellaria baicalensis, soaking in clean water for 20-30 min, heating to strong fire, turning to slow fire, decocting for 30-60 min, concentrating, and filtering to obtain filtrate, namely the scutellaria baicalensis extract; the Coptidis rhizoma extract is obtained in the same manner.

Compared with the prior art, the contact lens care solution has the following advantages:

the contact lens care solution disclosed by the invention has a moisturizing effect through glycerin and sodium hyaluronate which are used as moisturizers, the menthol can play a cooling and itching relieving effect through adding, and the radix scutellariae extract and the rhizoma coptidis extract have antibacterial and anti-inflammatory effects and can effectively prevent inflammation and itching of eyes; the eye mask has good sterilization and disinfection effects on lenses, has good moisture retention and bacteriostasis, and can relieve eye dryness and itching after being worn for a long time.

Detailed Description

Unless defined otherwise, technical terms used in the following examples have the same meanings as commonly understood by one of ordinary skill in the art to which the present invention belongs. The test reagents used in the following examples, unless otherwise specified, are all conventional biochemical reagents; the experimental methods are conventional methods unless otherwise specified.

The present invention will be described in detail with reference to examples.

Example 1

Weighing the following components in parts by weight:

5 parts of sodium chloride, 10 parts of sodium dihydrogen phosphate, 3 parts of taurine, 3 parts of EDTA-2Na, 0.2 part of glycerol, 0.1 part of sodium hyaluronate, 4071 parts of poloxamer, 0.1 part of sodium citrate, 3 parts of polyhexamethylene biguanide hydrochloride, 0.5 part of menthol, 2 parts of radix scutellariae extract, 0.5 part of coptis chinensis extract and 120 parts of purified water.

Wherein the scutellaria extract and the coptis extract are obtained by the following steps:

cleaning the radix scutellariae, soaking the radix scutellariae in clear water for 20-30 min, heating the water to strong fire, turning the water to slow fire, decocting the water for 30-60 min, concentrating the water, and filtering the concentrated water to obtain filtrate, namely the radix scutellariae extract; the Coptidis rhizoma extract is obtained in the same manner.

Dissolving weighed sodium chloride, sodium dihydrogen phosphate, taurine, EDTA-2Na, a humectant, a detergent, polyhexamethylene biguanide hydrochloride and menthol into 60 parts of purified water to obtain a solution A;

dissolving the weighed traditional Chinese medicine extract in the remaining 60 parts of purified water to obtain a solution B;

uniformly mixing the solution A and the solution B, adjusting the pH to 7, and controlling the osmotic pressure to be 300mOsm/kg & H₂O；

Filtering the solution with the adjusted pH value through a 5-micron filter, and sterilizing to obtain the contact lens care solution.

Example 2

On the basis of the embodiment 1, different from the embodiment 1, the components are weighed according to the following parts by weight:

3 parts of sodium chloride, 5 parts of sodium dihydrogen phosphate, 2 parts of taurine, 2 parts of EDTA-2Na, 0.1 part of glycerol, 0.3 part of sodium hyaluronate, 4070.1 parts of poloxamer, 1 part of sodium citrate, 2 parts of polyhexamethylene biguanide hydrochloride, 0.3 part of menthol, 1 part of radix scutellariae extract, 1 part of coptis chinensis extract and 120 parts of purified water.

The other preparation process was the same as in example 1.

Example 3

On the basis of the embodiment 1, different from the embodiment 1, the components are weighed according to the following parts by weight:

1 part of sodium chloride, 2 parts of sodium dihydrogen phosphate, 1 part of taurine, 1 part of EDTA-2Na, 0.2 part of glycerol, 0.3 part of sodium hyaluronate, 4070.5 parts of poloxamer, 0.5 part of sodium citrate, 0.5 part of polyhexamethylene biguanide hydrochloride, 0.1 part of menthol, 21 parts of radix scutellariae extract, 3 parts of coptis chinensis extract and 100 parts of purified water.

The other preparation process was the same as in example 1.

The contact lens care solution can effectively relieve the dry, itching and red eyes when being worn for a long time.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.