阅读说明：本技术 一种制氢中药组合物及其应用 (Traditional Chinese medicine composition for hydrogen production and application thereof ) 是由 田利杰 王家胜 谢思佳 于 2021-09-10 设计创作，主要内容包括：本发明提供一种制氢中药组合物,以质量份计,包括以下组分：1-20份制氢材料、5-30份碳酸氢盐、10-50份有机酸、10-50份成型剂、0.1-10份稳定剂,5-40份中药组合物。能够获得纯度较高的氢,且较为稳定,便于存储携带。本发明还提供了所述制氢中药组合物的应用。(The invention provides a hydrogen production traditional Chinese medicine composition which comprises the following components in parts by mass: 1-20 parts of hydrogen production material, 5-30 parts of bicarbonate, 10-50 parts of organic acid, 10-50 parts of forming agent, 0.1-10 parts of stabilizing agent and 5-40 parts of traditional Chinese medicine composition. Can obtain hydrogen with higher purity, is more stable and is convenient to store and carry. The invention also provides application of the hydrogen production traditional Chinese medicine composition.)

1. The traditional Chinese medicine composition for hydrogen production is characterized by comprising the following components in parts by mass: 1-20 parts of hydrogen production material, 5-30 parts of bicarbonate, 10-50 parts of organic acid, 10-50 parts of forming agent, 0.1-10 parts of stabilizing agent and 5-40 parts of traditional Chinese medicine composition.

2. The hydrogen production traditional Chinese medicine composition according to claim 1, characterized by further comprising, by mass, 0.1-5 parts of a water purifying agent.

3. The hydrogen production traditional Chinese medicine composition according to claim 2, wherein the water purifying agent comprises at least one of calcium sulfite, inorganic silver antibacterial agent, nano-graphene, bamboo charcoal and activated carbon.

4. The hydrogen-producing traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the hydrogen-producing material comprises at least one of magnesium powder, magnesium hydride powder, calcium hydride powder, hydrogen-containing coral calcium powder, hydrogen-containing oyster powder, sodium borohydride and nano silicon powder.

5. The hydrogen-producing traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the bicarbonate comprises at least one of sodium bicarbonate, magnesium bicarbonate, calcium bicarbonate.

6. The hydrogen-producing traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the organic acid comprises a carboxylic acid, preferably the carboxylic acid comprises at least one of glycolic acid, malonic acid, malic acid, citric acid, tartaric acid, and acetic acid.

7. The hydrogen-producing traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the forming agent comprises at least one of maltodextrin and lactose.

8. The hydrogen-producing traditional Chinese medicine composition according to any one of claims 1 to 3, wherein the stabilizer comprises at least one of compressible starch, magnesium stearate, polyethylene glycol and microcrystalline cellulose.

9. The hydrogen-producing traditional Chinese medicine composition according to any one of claims 1 to 3, which is characterized by comprising the following components: 8-12 parts of raw astragalus, 3-5 parts of safflower, 1-3 parts of radix sophorae flavescentis, 4-6 parts of rhizoma atractylodis, 4-6 parts of peach kernel, 4-6 parts of red paeony root and 2-4 parts of angelica; or, 8-12 parts of folium artemisiae argyi, 3-5 parts of safflower, 8-12 parts of ginger, 2-4 parts of pseudo-ginseng, 3-5 parts of cinnamon and 1-3 parts of salvia miltiorrhiza; or, 8-12 parts of ginger, 8-12 parts of folium artemisiae argyi, 3-5 parts of safflower, 4-6 parts of pseudo-ginseng, 2-4 parts of cinnamon and 1-3 parts of radix sophorae flavescentis; or, 8-12 parts of motherwort, 8-12 parts of safflower, 4-6 parts of ginger, 4-6 parts of folium artemisiae argyi, 2-4 parts of angelica, 1-3 parts of rhizoma cyperi and 0.5-2 parts of ligusticum wallichii; or 6-10 parts of radix sophorae flavescentis, 5-7 parts of cortex phellodendri, 4-6 parts of clove, 2-4 parts of calcined dragon bone, 1-3 parts of flos sophorae, 1-3 parts of gallnut, 1-3 parts of radix curcumae, 1-3 parts of fructus kochiae, 1-3 parts of radix sanguisorbae, 1-3 parts of alum and 0.5-2 parts of rheum officinale; or 8-12 parts of divaricate saposhnikovia root, 8-12 parts of cicada fungus, 6-10 parts of Chinese angelica, 1-3 parts of red sage root and 1-3 parts of astragalus root.

10. The application of the hydrogen production traditional Chinese medicine composition according to any one of claims 1 to 9 is characterized in that the hydrogen production traditional Chinese medicine composition is used for preparing a health-care product for adjuvant therapy of rheumatoid arthritis, insomnia, hyperglycemia, cold womb, foot diseases, low back and leg pain, climacteric syndrome, low immunity, dysfunction of spleen and stomach, stagnation of liver qi, or fatigue.

11. Use of the hydrogen-generating Chinese medicinal composition according to any one of claims 1 to 9 in bathing, or foot care, or oral care, or skin beauty, or hair care, or feminine care.

12. The application of the hydrogen production traditional Chinese medicine composition is characterized in that the hydrogen production traditional Chinese medicine composition as claimed in any one of claims 1 to 9 is in the form of tablets, pills, powder, paste, pellets, oil, suppositories or granules.

Technical Field

The invention relates to the field of hydrogen production and health care, in particular to a hydrogen production traditional Chinese medicine composition and application thereof.

Background

Hydrogen is an excellent antioxidant because the hydrogen molecules are very fine and can enter the body and penetrate cell membranes to take away malignant active oxygen and synthesize water to be discharged out of the body without influencing the operation of other benign active oxygen and body functions. The Hydrogen in Water has strong reducing power, and Hydrogen ion-rich plain Water (Hydrogen Water), which is Hydrogen reducing Water, can remove excessive active oxygen (oxygen free radical) in the body by the reducing power, unlike common Water.

The powdered bath cosmetic disclosed in publication No. CN103585029A introduces a hydrogen-producing material into the field of skin care for bathing, but has the problems of easy moisture absorption and instability, the need to add a moisture-proof material, strict requirements for packaging and storage, limitations on use conditions, and limited hydrogen production.

How to obtain a stable hydrogen production material with high hydrogen production and convenient storage and transportation and use and also can be used for health care?

Disclosure of Invention

Aiming at the problems of low hydrogen production purity, small quantity, unstable hydrogen production material, high requirements on storage and transportation conditions and the like in the prior art, the invention aims to provide the hydrogen production traditional Chinese medicine composition which can obtain hydrogen with high purity, is stable, is convenient to store and carry and effectively solves the existing problems.

In order to achieve the purpose of the application, the invention adopts the following technical scheme:

the invention provides a hydrogen production traditional Chinese medicine composition which comprises the following components in parts by mass: 1-20 parts of hydrogen production material, 5-30 parts of bicarbonate, 10-50 parts of organic acid, 10-50 parts of forming agent, 0.1-10 parts of stabilizing agent and 5-40 parts of traditional Chinese medicine composition. Preferably, the hydrogen production traditional Chinese medicine composition also comprises 0.1-5 parts of water purifying agent by mass; preferably, the water purifying agent comprises at least one of calcium sulfite, inorganic silver antibacterial agent, nano-graphene, bamboo charcoal and activated carbon. Preferably, the hydrogen production material comprises at least one of magnesium powder, magnesium hydride powder, calcium hydride powder, hydrogen-containing coral calcium powder, hydrogen-containing oyster powder, sodium borohydride and nano silicon powder. Preferably, the bicarbonate comprises at least one of sodium bicarbonate, magnesium bicarbonate, calcium bicarbonate. Preferably, the organic acid comprises a carboxylic acid, or the organic acid is a carboxylic acid; preferably, the carboxylic acid comprises at least one of glycolic acid, malonic acid, malic acid, citric acid, tartaric acid, acetic acid. Preferably, the forming agent comprises at least one of maltodextrin and lactose. Preferably, the stabilizer comprises at least one of compressible starch, magnesium stearate, polyethylene glycol and microcrystalline cellulose.

The traditional Chinese medicine composition can be a traditional Chinese medicine composition in the prior art, can be a traditional Chinese medicine formula described in the prior patent, such as the traditional Chinese medicine formula described in the application number CN201310199140.1 and the application number CN200610002152.0, and can also be described in the prior article. Preferably, the traditional Chinese medicine composition comprises, by mass, 8-12 parts of raw astragalus, 3-5 parts of safflower, 1-3 parts of radix sophorae flavescentis, 4-6 parts of rhizoma atractylodis, 4-6 parts of peach kernel, 4-6 parts of red paeony root and 2-4 parts of angelica; or, 8-12 parts of folium artemisiae argyi, 3-5 parts of safflower, 8-12 parts of ginger, 2-4 parts of pseudo-ginseng, 3-5 parts of cinnamon and 1-3 parts of salvia miltiorrhiza; or, 8-12 parts of ginger, 8-12 parts of folium artemisiae argyi, 3-5 parts of safflower, 4-6 parts of pseudo-ginseng, 2-4 parts of cinnamon and 1-3 parts of radix sophorae flavescentis; or, 8-12 parts of motherwort, 8-12 parts of safflower, 4-6 parts of ginger, 4-6 parts of folium artemisiae argyi, 2-4 parts of angelica, 1-3 parts of rhizoma cyperi and 0.5-2 parts of ligusticum wallichii; or 6-10 parts of radix sophorae flavescentis, 5-7 parts of cortex phellodendri, 4-6 parts of clove, 2-4 parts of calcined dragon bone, 1-3 parts of flos sophorae, 1-3 parts of gallnut, 1-3 parts of radix curcumae, 1-3 parts of fructus kochiae, 1-3 parts of radix sanguisorbae, 1-3 parts of alum and 0.5-2 parts of rheum officinale; or 8-12 parts of divaricate saposhnikovia root, 8-12 parts of cicada fungus, 6-10 parts of Chinese angelica, 1-3 parts of red sage root and 1-3 parts of astragalus root.

Preferably, the traditional Chinese medicine composition comprises, by mass, 10 parts of raw astragalus, 4 parts of safflower, 2 parts of sophora flavescens, 5 parts of rhizoma atractylodis, 5 parts of peach kernel, 5 parts of red peony root and 3 parts of angelica; or, 10 parts of folium artemisiae argyi, 4 parts of safflower, 10 parts of ginger, 3 parts of pseudo-ginseng, 4 parts of cinnamon and 2 parts of salvia miltiorrhiza; or 10 parts of ginger, 10 parts of folium artemisiae argyi, 4 parts of safflower, 5 parts of pseudo-ginseng, 3 parts of cinnamon and 2 parts of radix sophorae flavescentis; or, 10 parts of motherwort, 10 parts of safflower, 5 parts of ginger, 5 parts of folium artemisiae argyi, 3 parts of angelica, 2 parts of rhizoma cyperi and 1 part of ligusticum wallichii; or 8 parts of radix sophorae flavescentis, 6 parts of cortex phellodendri, 5 parts of clove, 3 parts of calcined dragon bone, 2 parts of flos sophorae, 2 parts of gallnut, 2 parts of radix curcumae, 2 parts of fructus kochiae, 2 parts of sanguisorba officinalis, 2 parts of alum and 1 part of rheum officinale; or 10 parts of divaricate saposhnikovia root, 10 parts of cicada fungus, 8 parts of Chinese angelica, 2 parts of red sage root and 2 parts of astragalus root.

The components mentioned in the application, such as safflower, rhizoma atractylodis, peach kernel, red peony root, folium artemisiae argyi, cicada fungus, ginger, cinnamon, motherwort, angelica, clove, gallnut, radix curcumae, fructus kochiae, rheum officinale, radix saposhnikoviae, astragalus, radix sophorae flavescentis, red peony root, folium artemisiae argyi, pseudo-ginseng, cinnamon, rhizoma cyperi, salvia miltiorrhiza, ligusticum wallichii, cortex phellodendri, sophora flower, gallnut, garden burnet, raw astragalus root and the like, refer to raw material medicines of the components or raw material medicine extracts, taking safflower as an example, and the safflower containing 3-5 parts of safflower refers to 3-5 parts of safflower (raw material medicines) or 3-5 parts of safflower extracts. The way of obtaining the extract is the way of obtaining the extract of the raw material medicine recorded in the prior art. The invention provides application of a hydrogen production traditional Chinese medicine composition in preparing a health care product for adjuvant therapy of rheumatic arthritis, insomnia, hyperglycemia, cold womb, foot diseases, low back and leg pain, climacteric syndrome, low immunity, dysfunction of spleen and stomach, liver qi stagnation or easy fatigue. Insomnia refers to the general term of the symptoms of insomnia, such as dizziness, cardialgia, palpitation, amnesia, mental fatigue, and heart-mind disorder, which are caused by insomnia. The foot diseases refer to foot discomfort such as tinea pedis, foot itching, sweaty feet, smelly feet and the like.

The invention provides application of a hydrogen-making traditional Chinese medicine composition in bathing, foot care, oral care, skin beautifying, hair care or female care. The product (namely the hydrogen-producing traditional Chinese medicine composition) is placed in bath water during bathing. The foot care method comprises soaking the product in foot washing water. The oral cavity care product can be used for gargling with water containing the product, or brushing teeth, or removing water retention containing the product. The product can be placed in water for skin care, and the obtained liquid can be applied on face or skin of other parts; or spraying the obtained liquid onto the skin in the form of a spray, or cleaning the skin using the obtained liquid. Hair care, can be used for promoting hair growth, and is prepared by soaking the product in water, applying the obtained liquid on scalp, and massaging to absorb. Female care, putting the product in water, and collecting the obtained liquid for vulva or vagina cleaning.

The invention provides a preparation formulation of a hydrogen production traditional Chinese medicine composition, which can be tablets, pills, powder, paste, pellets, oil or granules.

The hydrogen production traditional Chinese medicine composition is relatively stable, is convenient to store and carry, and can obtain hydrogen with relatively high purity. The hydrogen production material is combined with the Chinese herbal medicines, and the leaching and absorption of the effective substances of the Chinese herbal medicines can be facilitated by means of the synergistic enhancement effect of the hydrogen molecules and the Chinese herbal medicines and the antioxidation and transdermal properties of the hydrogen molecules.

DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION

For the purpose of facilitating an understanding of the present invention, the present invention will now be described by way of examples. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as limiting the present invention, and the structural, methodological or functional changes made by those skilled in the art according to the embodiments are included in the scope of the present invention. The step designations in the present disclosure do not denote any order of performing the steps, unless otherwise specified.

The parts are parts by mass if not specially marked.

The invention provides a hydrogen production traditional Chinese medicine composition which comprises the following components in parts by mass: 1-20 parts (1 part, 3 parts, 5 parts, 6 parts, 7 parts, 10 parts, 12 parts, 13 parts, 15 parts, 16 parts, 18 parts and 20 parts) of hydrogen production material, 5-30 parts (5 parts, 7 parts, 8 parts, 10 parts, 13 parts, 15 parts, 18 parts, 20 parts, 22 parts, 25 parts, 28 parts and 30 parts) of bicarbonate, 10-50 parts (10 parts, 15 parts, 18 parts, 20 parts, 23 parts, 25 parts, 28 parts, 30 parts, 35 parts, 38 parts, 40 parts, 45 parts, 48 parts and 50 parts) of organic acid, 10-50 parts (10 parts, 15 parts, 18 parts, 20 parts, 23 parts, 25 parts, 28 parts, 30 parts, 35 parts, 38 parts, 40 parts, 45 parts, 48 parts and 50 parts) of molding agent, 0.1-10 parts (0.1 part, 0.5 parts, 7.1 part, 1.5 parts, 2.5 parts, 2.1.5 parts and 2 parts of molding agent, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 4.8 parts, 5 parts, 5.5 parts, 6 parts, 6.5 parts, 7 parts, 7.5 parts, 8 parts, 8.5 parts, 9 parts, 9.5 parts and 10 parts of stabilizer and 5-40 parts of traditional Chinese medicine composition (5 parts, 10 parts, 15 parts, 18 parts, 20 parts, 23 parts, 25 parts, 28 parts, 30 parts, 35 parts, 38 parts and 40 parts can be selected). The bicarbonate and the organic acid have a synergistic disintegration effect, in addition, in the acid-base ratio range of the formula, the acid component ratio is slightly high, the acidic environment can be provided for exciting to rapidly produce hydrogen, the speed and the amount of hydrogen preparation are improved, and the skin beautifying effect is achieved. The forming agent has excellent lubricity and cohesiveness, and is an excipient and an excipient carrier when preparing tablets. The stabilizer increases the stability of the hydrogen production traditional Chinese medicine composition, and particularly enables the shape to be complete when the hydrogen production traditional Chinese medicine composition is prepared into tablets. Preferably, the hydrogen production traditional Chinese medicine composition further comprises, by mass, 0.1-5 parts (which may be 0.1 part, 0.5 part, 0.7 part, 1 part, 1.3 parts, 1.5 parts, 1.7 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 4.8 parts, 5 parts) of a water purifying agent; preferably, the water purifying agent comprises at least one of calcium sulfite, inorganic silver antibacterial agent, nano-graphene, bamboo charcoal and activated carbon. The introduced water purifying agent has the following functions: (1) purifying residual chlorine and other organic matters in water; (2) the antibacterial and antiseptic effects are achieved; (3) the calcium sulfite has good reducibility and can synergistically reduce the negative potential of water with hydrogen; (4) and the problem that the material is easy to deliquesce can be solved. . Preferably, the hydrogen production material comprises at least one of magnesium powder, magnesium hydride powder, calcium hydride powder, hydrogen-containing coral calcium powder, hydrogen-containing oyster powder, sodium borohydride and nano silicon powder. Preferably, the particle size of the magnesium powder is 10-500 microns, and the purity is more than 95%; the particle size of the magnesium hydride powder is 1-100 microns, and the purity is more than 90%; the nanometer silicon powder is 10-1000 nanometers. Preferably, the bicarbonate comprises at least one of sodium bicarbonate, magnesium bicarbonate, calcium bicarbonate. Preferably, the organic acid comprises a carboxylic acid, or the organic acid is a carboxylic acid; preferably, the carboxylic acid comprises at least one of glycolic acid, malonic acid, malic acid, citric acid, tartaric acid, acetic acid. Preferably, the forming agent comprises at least one of maltodextrin and lactose. Preferably, the stabilizer comprises at least one of compressible starch, magnesium stearate, polyethylene glycol and microcrystalline cellulose. The hydrogen-producing traditional Chinese medicine composition can be in the form of powder, granule or tablet.

Preferably, the traditional Chinese medicine composition comprises, by mass, 8-12 parts of raw astragalus, 3-5 parts of safflower, 1-3 parts of radix sophorae flavescentis, 4-6 parts of rhizoma atractylodis, 4-6 parts of peach kernel, 4-6 parts of red paeony root and 2-4 parts of angelica; or, 8-12 parts of folium artemisiae argyi extract, 3-5 parts of safflower extract, 8-12 parts of ginger extract, 2-4 parts of pseudo-ginseng extract, 3-5 parts of cinnamon extract and 1-3 parts of salvia miltiorrhiza extract; or, 8-12 parts of ginger, 8-12 parts of folium artemisiae argyi, 3-5 parts of safflower, 4-6 parts of pseudo-ginseng, 2-4 parts of cinnamon and 1-3 parts of radix sophorae flavescentis; or, 8-12 parts of motherwort, 8-12 parts of safflower, 4-6 parts of ginger, 4-6 parts of folium artemisiae argyi, 2-4 parts of angelica, 1-3 parts of rhizoma cyperi and 0.5-2 parts of ligusticum wallichii; or 6-10 parts of radix sophorae flavescentis, 5-7 parts of cortex phellodendri, 4-6 parts of clove, 2-4 parts of calcined dragon bone, 1-3 parts of flos sophorae, 1-3 parts of gallnut, 1-3 parts of radix curcumae, 1-3 parts of fructus kochiae, 1-3 parts of radix sanguisorbae, 1-3 parts of alum and 0.5-2 parts of rheum officinale; or 8-12 parts of divaricate saposhnikovia root, 8-12 parts of cicada fungus, 6-10 parts of Chinese angelica, 1-3 parts of red sage root and 1-3 parts of astragalus root.

Note: the mass part relation of different Chinese herbal medicines characterizes the proportional relation among the different Chinese herbal medicines.

The above materials are all available on the market, or prepared according to related patents or articles or pharmacopoeias, and can be purchased or self-made according to actual needs. For example, the hydrogen-containing coral calcium powder can be obtained from Shanghai Quanren Biotech Co., Ltd, and the hydrogen-containing oyster powder can be obtained from sunshine Life grain Biotech development Co., Ltd. The invention mostly adopts the method of pulverizing Chinese herbal medicines into powder, and can be dried and pulverized into powder, or the Chinese herbal medicines are firstly extracted with water to obtain water extract, and then concentrated and dried to obtain powder, or the Chinese herbal medicines are prepared into extract for use. For example, ginger, astragalus, safflower, sophora flavescens, radix rehmanniae, red peony root, wolfberry fruit and the like can be dried and milled into powder for use, or water is firstly extracted to obtain a water extract, and then concentrated and dried to obtain powder, or other required formulations such as powder, paste, suspension and the like are prepared by other prior arts, and the extracts of artemisia leaf extract, safflower extract, ginger extract, pseudo-ginseng extract, cinnamon extract, salvia miltiorrhiza extract and the like can be extracted according to the requirements by the prior arts, such as water extraction, alcohol extraction, oil extraction and the like. In some embodiments of the invention, safflower, rhizoma atractylodis, peach kernel, red paeony root, folium artemisiae argyi, cicada flower, ginger, cinnamon, motherwort, angelica, clove, sophora flower, gallnut, radix curcumae, fructus kochiae, rhubarb, radix sileris, astragalus mongholicus and peach kernel are subjected to water extraction to obtain a liquid water extract, and then the liquid water extract is subjected to spray drying to obtain the extract. In some embodiments of the invention, safflower, peach kernel, lightyellow sophora root, red paeony root, argyi leaf, pseudo-ginseng, cassia bark, nutgrass galingale rhizome, danshen root, szechuan lovage rhizome, amur corktree bark, sophora flower, Chinese gall, garden burnet root, rhubarb and divaricate saposhnikovia root are subjected to alcohol extraction to obtain liquid alcohol extract, and then the liquid alcohol extract is subjected to spray drying to obtain the extract. In some embodiments of the invention, raw astragalus, alum and calcined keel are ground into powder for direct use.

The hydrogen-producing traditional Chinese medicine composition can be prepared into tablets, pills, powder, paste, pellets, oil, suppositories or granules. Can be introduced into the auxiliary materials in the prior art according to the preparation requirements of different dosage forms. Tablets, pills, powders, ointments, pellets, suppositories can be described with reference to hundred degrees. The oil agent can be oily suspension obtained by mixing the hydrogen-producing traditional Chinese medicine composition and proper oil, and the granular preparation can be dry granular preparation with certain granularity prepared by mixing the raw material medicine (the hydrogen-producing traditional Chinese medicine composition) and proper auxiliary materials.

Dried rehmannia root: radix rehmanniae has effects of nourishing yin and clearing heat, and can inhibit and prevent blood sugar rise caused by epinephrine, and improve diabetic hyperlipidemia and hypertension. Red peony root: the red peony root is very important, has the effects of dissipating blood stasis and clearing heat, and has the effects of reducing blood sugar, blood fat and the like due to the fact that the red peony root can improve the resistance of human insulin as proved by modern pharmacology. Wolfberry fruit: the medlar has a plurality of functions and is believed to have the efficacies of tonifying the kidney, nourishing the liver, quenching thirst and the like, and related experiments show that the medlar extract can promote the blood sugar of animals to be reduced for a long time, so the medlar can improve the blood sugar rise of diabetes. Red sage root: has the functions of promoting blood circulation, cooling blood and nourishing blood, can remove blood stasis and dredge collaterals, and the salvia miltiorrhiza decoction can obviously reduce the blood sugar of experimental animals, can last for 5 hours and can reduce the blood fat and the blood viscosity. Chinese angelica: the product has effects in replenishing blood, promoting blood circulation, loosening bowel to relieve constipation, protecting liver, preventing hepatic glycogen reduction, tranquilizing, relieving pain, and relieving inflammation. Kudzu root: the product has effects of relieving exterior syndrome, expelling pathogenic factors from muscles, invigorating yang, promoting eruption, relieving fever, and promoting fluid production, and has remarkable effect in lowering blood sugar. Raw Chinese yam: the amylase contained in the medicine has the function of hydrolyzing starch into glucose, and has certain curative effect on diabetes. Cortex lycii radicis: the medicine contains unsaturated and essential fatty acid, linoleic acid, linolenic acid, etc. It has anti-fat effect, and can inhibit the synthesis of neutral fat in liver, promote the neutral fat to move to blood flow, so as to ensure the physiological function of liver to maintain normal blood sugar, and reduce blood sugar to control disease state. Corn silk: the medicine contains saccharide and malic acid, and has effects of promoting urination and lowering blood pressure. It can promote bile secretion; reducing the viscosity of blood; and can increase prothrombin in blood and accelerate blood coagulation. Rhizoma polygonati: the medicine contains mucus, starch, sugar, etc. It has effects in resisting fatty liver, reducing blood sugar and blood pressure, and preventing atherosclerosis; has good curative effect on tinea pedis and tinea cruris. Figwort root: the medicine has effects of dilating blood vessel; it also has effects in lowering blood sugar and lowering blood pressure. Astragalus root: the medicine has obvious cardiotonic effect, can strengthen contraction of normal heart, and has obvious cardiotonic effect on heart caused by poisoning or fatigue. In addition, it can protect liver cells, prevent reduction of liver glycogen, and promote liver cell regeneration; has blood pressure lowering effect; it can dilate coronary blood vessel and peripheral blood vessel of whole body, and improve skin blood circulation and nutrition status; has slight effect of reducing blood sugar. Ginseng: the medicine can promote metabolism of human body and enhance resistance of organism to external adverse conditions. It can lower the normal blood sugar and hyperglycemia due to adrenalin or hypertonic glucose, and slightly lower blood sugar, but can not prevent morbidity and mortality. The Ginseng radix extract also has blood sugar level regulating effect. Gynostemma pentaphylla: it is cold in nature and bitter in taste, and has effects of diminishing inflammation, removing toxic substance, relieving cough, eliminating phlegm, clearing heat and moistening dryness. One of the special components is dulcoside, which has the functions of nourishing, resisting senility, eliminating fat, lowering blood sugar, diminishing inflammation, preventing cancer, eliminating fatigue, etc. Gynostemma pentaphyllum has effects of reducing blood sugar and improving sugar metabolism. The herba Gynostemmatis extract and its saponin have physiological activity similar to that of Ginseng radix, and have effects of delaying aging, reducing blood lipid, reducing blood glucose, resisting cancer, regulating immunity, resisting myocardial ischemia, resisting thrombosis, resisting toxic substance, and protecting liver. Rhubarb: radix et rhizoma Rhei has effects of reducing blood viscosity, improving microcirculation, increasing pancreatic blood supply, and inhibiting endotoxemia. Radix et rhizoma Rhei can reduce insulin resistance, and enhance binding force of insulin and cell receptor, thereby improving glycometabolism and treating diabetes. Cortex mori and mulberries: the research on the blood sugar reducing effect of 50 traditional medicines for treating diabetes shows that the mulberry bark and mulberry have obvious blood sugar reducing effect, and especially the mulberry bark has the most obvious blood sugar reducing effect. Guava: animal and clinical researches on guava leaves and fruits show that the effective component of the guava leaves is flavonoid glycoside, has the effects of promoting the combination of insulin and specific receptors on target cell membranes, regulating glycometabolism and lipid metabolism, reducing blood sugar and certain effects of reducing blood pressure and blood fat. Balloon flower: the key point of blood sugar reduction is as follows: platycodin contained in platycodon grandiflorum has obvious effect of reducing blood sugar and has good curative effect on diabetes complicated with dry thirst and dysphoria with smothery sensation. Rhizoma anemarrhenae: the water extract of rhizoma anemarrhenae can help people to quickly reduce blood sugar, and the rhizoma anemarrhenae, the Mongolian snakegourd root and the dwarf lilyturf tuber are put together and decocted, so that the symptoms of thirst and polydipsia caused by diabetes can be improved. Bitter gourd: the balsam pear extract has good blood sugar reducing effect and is called as plant insulin. The above materials can also be decocted in water to obtain extract, and spray drying to obtain powder.

The hydrogen production traditional Chinese medicine composition can be pressed into effervescent tablets and used for bathing or foot bath and the like. The efficacy of the product is illustrated below by taking tablets as an example.

Example 1 preparation of a Hydrogen-producing Chinese medicinal composition and tableting

Hydrogen production traditional Chinese medicine composition No. 1: 1 part of magnesium powder (65 microns), 18 parts of sodium bicarbonate, 22 parts of glycolic acid, 19 parts of maltodextrin, 60005 parts of polyethylene glycol, 10 parts of raw astragalus, 4 parts of safflower, 2 parts of radix sophorae flavescentis, 5 parts of rhizoma atractylodis, 5 parts of peach kernel, 5 parts of radix paeoniae rubra and 3 parts of angelica;

hydrogen production traditional Chinese medicine composition No. 2: 1 part of magnesium hydride (38 microns), 18 parts of sodium bicarbonate, 30 parts of malonic acid, 19 parts of maltodextrin, 60005 parts of polyethylene glycol, 1 part of calcium sulfite, 10 parts of raw astragalus, 4 parts of safflower, 2 parts of radix sophorae flavescentis, 5 parts of rhizoma atractylodis, 5 parts of peach kernel, 5 parts of radix paeoniae rubra and 3 parts of angelica;

hydrogen production traditional Chinese medicine composition No. 3: 1 part of calcium hydride (28 microns), 18 parts of sodium bicarbonate, 40 parts of malic acid, 19 parts of maltodextrin, 60005 parts of polyethylene glycol, 2 parts of calcium sulfite, 10 parts of raw astragalus, 4 parts of safflower, 2 parts of radix sophorae flavescentis, 5 parts of rhizoma atractylodis, 5 parts of peach kernel, 5 parts of radix paeoniae rubra and 3 parts of angelica;

hydrogen production traditional Chinese medicine composition No. 4: 5 parts of magnesium powder (65 microns), 18 parts of sodium bicarbonate, 22 parts of citric acid, 17 parts of maltodextrin, 60005 parts of polyethylene glycol, 10 parts of folium artemisiae argyi extract, 4 parts of safflower extract, 10 parts of ginger extract, 3 parts of pseudo-ginseng extract, 4 parts of cinnamon extract, 2 parts of salvia miltiorrhiza extract and 1 part of calcium sulfite;

hydrogen production traditional Chinese medicine composition No. 5: 5 parts of magnesium powder (65 microns), 18 parts of sodium bicarbonate, 32 parts of citric acid, 7 parts of maltodextrin, 60003 parts of polyethylene glycol, 10 parts of folium artemisiae argyi extract, 4 parts of safflower extract, 10 parts of ginger extract, 3 parts of pseudo-ginseng extract, 4 parts of cinnamon extract, 2 parts of salvia miltiorrhiza extract and 1 part of calcium sulfite;

hydrogen production traditional Chinese medicine composition No. 6: 5 parts of magnesium powder (65 microns), 18 parts of sodium bicarbonate, 35 parts of citric acid, 4 parts of maltodextrin, 60005 parts of polyethylene glycol, 10 parts of folium artemisiae argyi extract, 4 parts of safflower extract, 10 parts of ginger extract, 3 parts of pseudo-ginseng extract, 4 parts of cinnamon extract, 2 parts of salvia miltiorrhiza extract and 1 part of calcium sulfite;

the materials are ball-milled or mechanically mixed according to respective proportions to obtain powdery or granular intermediate products, and then the intermediate products are pressed into tablets No. 1 to No. 6.

The ball-material ratio of the ball milling is 10-50: 1, and the ball milling time is 1-5 hours;

the stirring speed of the mechanical mixing is 5-400 r/min, and the stirring time is 0.5-3 hours.

Example 2 Hydrogen content testing

Each of tablets No. 1, No. 2 and No. 3 obtained in example 1 was taken and put in 500mL of purified water for disintegration test, a KH888 dissolved hydrogen/negative potential test pen manufactured in taiwan was inserted into a water cup for detection, and the results were as follows:

TABLE 1

The calcium sulfite powder is introduced into the formula, so that the effects of removing residual chlorine in water, purifying water quality, reducing oxidation-reduction potential value and the like can be realized.

Tablet No. 1, tablet No. 2 and tablet No. 3 are respectively distributed to 2 experiencers, 6 experiencers with high blood sugar are totally taken, and after the feet are insist for 10 days, 5 blood sugar is reduced.

Two tablets No. 4, No. 5 and No. 6 obtained in example 1 were each placed in 5L of water (40 to 50 ℃ C.), and the H content was measured over 1 hour.

TABLE 2

The hydrogen production traditional Chinese medicine composition comprises substances with different proportions, so that the disintegration speed is improved, and the reaction speed is accelerated.

Tablets No. 4, No. 5 and No. 6 were distributed to 2 experiencers respectively, and 6 experiencers were taken twice a week, and after one month, the skin condition was improved. Wherein, female experiencers feel the symptoms of dysmenorrhea and the symptoms of cold hands and feet are improved.

Example 3

Hydrogen production traditional Chinese medicine composition No. 7: 20 parts of hydrogen-containing coral calcium powder, 15 parts of calcium bicarbonate, 15 parts of sodium bicarbonate, 25 parts of glycolic acid, 25 parts of malonic acid, 11 parts of lactose, 8 parts of microcrystalline cellulose, 10 parts of ginger, 10 parts of folium artemisiae argyi, 4 parts of safflower, 5 parts of pseudo-ginseng, 3 parts of cinnamon and 2 parts of radix sophorae flavescentis; has effects of invigorating spleen, replenishing qi, dispersing stagnated liver qi, relieving qi stagnation, and improving sleep. The foot soaking tablet prepared from the hydrogen production Chinese medicinal composition No. 7 is used for soaking feet of people who cannot fall asleep normally or are difficult to fall asleep after waking up, and people with symptoms of dizziness, cardiodynia, palpitation, amnesia, mental fatigue, heart-mind imbalance and the like, and has better improvement. After the feet are soaked effectively, the sleep quality of most of the experiencers is improved.

Hydrogen production traditional Chinese medicine composition No. 8: 1 part of magnesium hydride (38 microns), 5 parts of magnesium powder (65 microns), 6 parts of hydrogen-containing oyster powder, 5 parts of sodium bicarbonate, 10 parts of malonic acid, 5 parts of citric acid, 3 parts of malic acid, 25 parts of maltodextrin, 25 parts of lactose, 60005 parts of polyethylene glycol, 1 part of calcium sulfite, 3 parts of nano-graphene, 1 part of inorganic silver antibacterial agent, 8 parts of raw astragalus, 5 parts of safflower extract, 3 parts of sophora flavescens extract, 4 parts of rhizoma atractylodis extract, 6 parts of peach kernel extract, 4 parts of red peony root extract and 4 parts of angelica sinensis extract; warming yang, dredging collaterals, promoting blood circulation, removing blood stasis, relieving exterior syndrome, clearing heat, relieving pain, promoting granulation, and lowering blood sugar. Is suitable for people with diabetes. According to a long-term rule, after the feet are effectively soaked or the bath is carried out, the blood sugar of most of experiencers is reduced.

Hydrogen production traditional Chinese medicine composition No. 9: 5 parts of sodium borohydride, 5 parts of nano silicon powder, 5 parts of magnesium bicarbonate, 50 parts of malic acid, 10 parts of lactose, 60003 parts of polyethylene glycol, 3 parts of magnesium stearate, 3 parts of compressible starch, 0.1 part of nano graphene, 10 parts of motherwort, 10 parts of safflower, 5 parts of ginger, 5 parts of folium artemisiae argyi, 3 parts of angelica, 2 parts of rhizoma cyperi and 1 part of ligusticum wallichii; nourishing blood and yin, and regulating and nourishing liver and kidney, and is suitable for people with cold uterus symptoms such as body weakness, weight loss, blood deficiency, infertility, etc.

Hydrogen production traditional Chinese medicine composition No. 10: 15 parts of hydrogen-containing oyster powder, 25 parts of sodium bicarbonate, 10 parts of malonic acid, 20 parts of maltodextrin, 0.5 part of compressible starch, 8 parts of radix sophorae flavescentis, 6 parts of cortex phellodendri, 5 parts of clove, 3 parts of calcined dragon bone, 2 parts of sophora flower, 2 parts of gallnut, 2 parts of radix curcumae, 2 parts of fructus kochiae, 2 parts of garden burnet, 2 parts of alum and 1 part of rhubarb; is suitable for people with tinea pedis, foot itching, sweaty foot, and foot odor. After the foot is effectively soaked, the discomfort of the foot of most of the experiencers is improved.

Hydrogen production traditional Chinese medicine composition No. 11: 5 parts of calcium hydride powder, 10 parts of sodium borohydride, 10 parts of sodium bicarbonate, 15 parts of magnesium bicarbonate, 35 parts of glycolic acid, 8 parts of maltodextrin, 9 parts of magnesium stearate, 3 parts of calcium sulfite, 10 parts of divaricate saposhnikovia root, 10 parts of cicada flower, 8 parts of angelica, 2 parts of salvia miltiorrhiza and 2 parts of astragalus membranaceus; benefiting liver and kidney, invigorating qi and blood, dispelling pathogenic wind and removing dampness, and dredging channels and collaterals. Is suitable for middle-aged and elderly people with deficiency of liver and kidney, deficiency of qi and blood, and lumbago and skelalgia. After the foot bath is effectively carried out, the waist and leg pain of most experiencers is improved.

Hydrogen production traditional Chinese medicine composition No. 12: 10 parts of nano silicon powder, 15 parts of magnesium bicarbonate, 3 parts of calcium bicarbonate, 25 parts of malonic acid, 20 parts of maltodextrin, 0.5 part of compressible starch, 10 parts of motherwort, 10 parts of safflower, 5 parts of ginger, 5 parts of folium artemisiae argyi, 3 parts of angelica, 2 parts of rhizoma cyperi and 1 part of ligusticum wallichii. Regularly, after regular bathing, the skin state of most experiencers is improved, and the dysmenorrhea symptom of female experiencers is improved.

Hydrogen production traditional Chinese medicine composition No. 13: 1 part of nano silicon powder, 9 parts of magnesium powder, 25 parts of calcium bicarbonate, 10 parts of malic acid, 18 parts of maltodextrin, 0.1 part of magnesium stearate, 4 parts of calcium sulfite and 0.5 part of inorganic silver antibacterial agent. Regularly, after regular bathing, the skin condition of most of the experiencers is improved. The pudendum pruritus symptom of some women is improved.

Hydrogen production traditional Chinese medicine composition No. 14: 9 parts of nano silicon powder, 5 parts of magnesium powder, 2 parts of calcium hydride powder, 28 parts of sodium bicarbonate, 10 parts of tartaric acid, 18 parts of maltodextrin, 6 parts of microcrystalline cellulose, 3 parts of bamboo charcoal, 8 parts of radix sophorae flavescentis, 6 parts of golden cypress, 5 parts of clove, 3 parts of calcined dragon bone, 2 parts of sophora flower, 2 parts of gallnut, 2 parts of radix curcumae, 2 parts of fructus kochiae, 2 parts of radix sanguisorbae, 2 parts of alum and 1 part of rhubarb.

After regularly and regularly soaking feet, most of experients improve aching pain in waist and legs, soften foot cutin, improve foot skin condition and relieve itching.

Hydrogen production traditional Chinese medicine composition No. 15: 12 parts of nano silicon powder, 25 parts of sodium bicarbonate, 35 parts of acetic acid, 28 parts of maltodextrin, 1.5 parts of magnesium stearate, 4 parts of bamboo charcoal, 1 part of calcium sulfite and 5 parts of sophora flower.

Periodically, after application to the face, the skin condition of most of the experienced persons is improved.

Hydrogen production traditional Chinese medicine composition No. 16: 9 parts of sodium borohydride, 25 parts of magnesium bicarbonate, 40 parts of acetic acid, 18 parts of maltodextrin, 4 parts of magnesium stearate, 4 parts of activated carbon, 5 parts of flos sophorae and 5 parts of clove.

Periodically, after bathing, the skin condition of most of the experienced persons is improved.

Example 4

In other embodiments, the Chinese medicinal composition can be other prescriptions.

(1) The formula is as follows: chinese angelica, dried orange peel, green tangerine peel, villous amomum fruit, red yeast rice, clove, malt, bitter orange, gardenia, officinal magnolia bark, wrinkled gianthyssop herb and costustoot.

The efficacy is as follows: soothing liver, regulating qi, and regulating spleen and stomach, and is suitable for middle-aged and elderly people with dyspepsia, hypochondriac distention and pain, and loose stool due to stagnation of qi due to depression of liver and incoordination between spleen and stomach.

(2) The formula is as follows: cassia bark, acanthopanax, liquorice, ginseng leaf, ligusticum wallichii, polygonum multiflorum, fructus alpiniae oxyphyllae and semen cuscutae.

The efficacy is as follows: relieving pressure, relieving fatigue, dispelling pathogenic wind and dampness, nourishing liver and kidney, and strengthening tendons and bones. Is suitable for people with chronic fatigue syndrome such as strenuous exercise, long-time work or after physical work, insufficient sleep, great thought pressure, inattentive attention, general fatigue, myasthenia, myalgia, inappetence, etc.

(3) The formula is as follows: semen Allii Tuberosi, radix Morindae officinalis, Eucommiae cortex, radix Codonopsis, radix astragali, fructus Lycii, testis Et penis bovis seu Bubali, Cistanchis herba, radix rehmanniae Preparata, semen Cuscutae, and rhizoma Zingiberis recens.

The efficacy is as follows: improving immunity, warming kidney, tonifying yang, strengthening essence, and tonifying yang. It is suitable for lumbago, tibial weakness, premature ejaculation, and sexual impotence due to kidney yang deficiency.

(4) The formula is as follows: radix sophorae flavescentis, rhizoma atractylodis, pericarpium zanthoxyli, cortex phellodendri, radix sileris, herba schizonepetae, liquorice, angelica sinensis and moutan bark.

The functions are as follows: has effects in expelling pathogenic wind, dispelling cold, promoting blood circulation, removing obstruction in collaterals, eliminating dampness, and relieving pain, and is suitable for treating arthralgia and myalgia due to wind-cold invasion, swelling and pain due to soft tissue injury, chronic lumbago, and rheumatic arthritis.

(5) The formula is as follows: coptis root, jujube kernel, ophiopogon root, white peony root, cynanchum atratum, salvia miltiorrhiza and dragon bone.

The functions are as follows: clearing away heart-fire, calming liver, mainly treating climacteric syndrome; is suitable for people with sweating due to heat, vexation, irritability, dry mouth, insomnia, palpitation, and climacteric syndrome.

Example 5

Hydrogen production traditional Chinese medicine composition No. 17: 20 parts of nano silicon powder, 20 parts of sodium bicarbonate, 30 parts of glycolic acid, 15 parts of lactose, 8 parts of microcrystalline cellulose, 12 parts of ginger, 8 parts of folium artemisiae argyi, 5 parts of safflower, 4 parts of pseudo-ginseng, 2 parts of cinnamon, 3 parts of radix sophorae flavescentis, 1 part of calcium sulfite and 2 parts of nano graphene.

Taking the traditional Chinese medicine formula of composition No. 17 as an example, the result of the extraction of the same amount of traditional Chinese medicines, hydrogen-rich water and common water is as follows: after the hydrogen is added, the traditional Chinese medicine can be dissolved out in a shorter time, the leaching solution is darker in color and stronger in taste, the super-strong permeability of hydrogen molecules is proved to be capable of promoting the dissolution of the effective substances of the Chinese herbal medicines, the hydrogen production material is combined with the Chinese herbal medicines, the synergistic enhancement effect of the hydrogen molecules and the Chinese herbal medicines and the antioxidation and transdermal properties of the hydrogen molecules can be utilized, and the leaching and absorption of the effective substances of the Chinese herbal medicines are facilitated.

The materials are ball milled or mechanically mixed according to respective proportions to obtain a powdery or granular intermediate product, and then the intermediate product is pressed into a tablet.

And (3) testing the hydrogen content: two tablets prepared from the hydrogen production traditional Chinese medicine composition No. 17 are taken and put into a cup containing 5L of purified water (40-50 ℃) for soaking. A KH888 dissolved hydrogen/negative potential test pen produced in Taiwan is inserted into a water cup for detection, the value is read, and the H content within 1 hour is tested.

TABLE 3

The data show that after the nano graphene is added, the hydrogen production capability of the hydrogen production traditional Chinese medicine composition is enhanced, on one hand, the antibacterial property of the material is enhanced, and on the other hand, the hydrogen production material micro-electrolysis reaction tank is added, so that the hydrogen production efficiency is improved.

Example 6

Hydrogen-producing Chinese medicinal composition No. 10 was compressed into tablets and distributed to the experiencers for use, with feedback as in Table 4.

TABLE 4

Hydrogen-producing Chinese medicinal composition No. 7 was compressed into tablets and distributed to the experiencers for use, with feedback as in Table 5.

TABLE 5

Under the premise of effective foot soaking, the physical condition of the experiencer is improved.

Example 7 other application scenarios of the Hydrogen-producing traditional Chinese medicine composition

1. And (3) beautifying and protecting skin: moisturizing and caring skin.

Placing the hydrogen-producing traditional Chinese medicine composition pieces in a container one by one, pouring a proper amount of purified water, standing for 5min, placing a compressed facial mask, taking out the facial mask and applying on the face for 10-15min after the mask cloth is full of essence.

b, placing the hydrogen-producing traditional Chinese medicine composition tablets one by one in a spray bottle, pouring a proper amount of purified water, standing for 5-10min, and spraying the tablets on the face to replenish water and preserve moisture after the tablets are completely dissolved.

And c, placing two hydrogen-producing Chinese medicinal composition tablets in a washbasin, pouring a proper amount of purified water, standing for 5-10min, and washing the face after the tablets are completely dissolved.

2. Gargling: sterilizing and inhibiting bacteria, and improving oral environment.

a, throwing 1 piece of hydrogen-producing traditional Chinese medicine composition mouth wash tablet into a water cup, and then, after dissolving, rinsing the mouth

b, directly putting the hydrogen-producing traditional Chinese medicine composition into the mouth, gargling for about 2min with a mouth of water, and spitting out.

Most of the subjects had improved halitosis, or improved staining.

3. Private protection: sterilizing, inhibiting bacteria, relieving itching and removing odor.

a vulvar cleaning and daily hygiene care: adding a piece of hydrogen-producing traditional Chinese medicine composition piece into a proper amount of water to dissolve completely, and washing the nursing part.

b, vaginal irrigation: dissolving a hydrogen-producing Chinese medicinal composition tablet in appropriate amount of water, and irrigating into a flusher for flushing the nursing part.

And c, plugging the vagina with a suppository.

The pudendum pruritus condition of most experiencers is improved.

4. Hair growth and hair restoration: relieving alopecia, increasing hair density, and promoting normal scalp environment.

Dissolving a hydrogen-producing Chinese medicinal composition tablet in appropriate amount of water, bottling, applying the liquid on scalp, and gently massaging for absorption. After long-term continuous use, the alopecia phenomenon of most of experiencers is improved.

The applicant states that the present invention is illustrated by the above examples to show the detailed process equipment and process flow of the present invention, but the present invention is not limited to the above detailed process equipment and process flow, i.e. it does not mean that the present invention must rely on the above detailed process equipment and process flow to be implemented. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.