阅读说明：本技术 单侧快速mri梯度场线圈及其应用 (Single-side fast MRI gradient field coil and application thereof ) 是由 亚历山大·纳塞夫 普尔基特·马利克 于 2020-03-25 设计创作，主要内容包括：公开了一种用于单侧磁共振成像系统的单侧梯度线圈组。该线圈组被配置为生成向外远离线圈组的磁场。该线圈组包括在相对于孔隙的第一位置处的一个或更多个第一螺旋线圈和在相对于孔隙的第二位置处的一个或更多个第二螺旋线圈。该线圈组被配置为使电流流过一个或更多个第一螺旋线圈和一个或更多个第二螺旋线圈以生成电磁场梯度,该电磁场梯度被配置为远离线圈组投射并进入磁成像系统的成像区域。(A single-sided gradient coil assembly for a single-sided magnetic resonance imaging system is disclosed. The coil assembly is configured to generate a magnetic field that is directed outwardly away from the coil assembly. The coil set includes one or more first spiral coils at a first location relative to the aperture and one or more second spiral coils at a second location relative to the aperture. The coil set is configured to flow current through the one or more first helical coils and the one or more second helical coils to generate electromagnetic field gradients configured to project away from the coil set and into an imaging region of the magnetic imaging system.)

1. A magnetic imaging apparatus comprising:

a power supply for supplying a current; and

a single-sided gradient coil set connected to the power supply, the coil set having an aperture,

wherein the coil set comprises one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture, and

wherein the coil set is configured to receive current through the one or more first helical coils and the one or more second helical coils, thereby generating an electromagnetic field gradient configured to project away from the coil set and into an imaging region of the magnetic imaging device.

2. The apparatus of claim 1, wherein the coil assembly is non-planar and oriented to partially surround the imaging region.

3. The apparatus of claim 1, wherein the one or more first spiral coils and the one or more second spiral coils are non-planar with respect to the aperture and mirror each other with respect to the aperture.

4. The apparatus of claim 1, wherein the electromagnetic field gradient is substantially uniform in the imaging region.

5. The apparatus of claim 1, wherein the electromagnetic field gradient is greater than about 5 mT.

6. The apparatus of claim 1, wherein the electromagnetic field gradient has a rise time of less than about 10 μ β.

7. The apparatus of claim 1, wherein the one or more first spiral coils comprise at least two first spiral coils having at least two different diameters.

8. The apparatus of claim 7, wherein the one or more second spiral coils comprise at least two second spiral coils having at least two different diameters.

9. The apparatus of claim 1, wherein the electrical current is configured to flow through the one or more first helical coils in alternating directions.

10. The apparatus of claim 9, wherein the electrical current is configured to flow through the one or more second spiral coils in alternating directions to minimize a rise time of the electromagnetic field gradient.

11. The apparatus of claim 1, wherein a primary first spiral coil of the one or more first spiral coils is configured to create a first large primary electromagnetic field gradient and a secondary first spiral coil of the one or more first spiral coils is configured to create a first small secondary electromagnetic field gradient to provide adjustment of the first large primary electromagnetic field gradient.

12. The apparatus of claim 11, wherein a primary second spiral coil of the one or more second spiral coils creates a second large primary electromagnetic field gradient and a secondary second spiral coil of the one or more second spiral coils is configured to create a second small secondary electromagnetic field gradient to provide adjustment of the second large primary electromagnetic field gradient.

13. The apparatus of claim 1, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil cause the current to flow through them in opposite directions.

14. The apparatus of claim 13, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil cause the current to flow through them in opposite directions.

15. The apparatus of claim 1, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil overlap by up to 50% of the respective coils to generate a more parallel first electromagnetic field gradient.

16. The apparatus of claim 15, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil overlap by up to 50% of the respective coils to generate a more parallel second electromagnetic field gradient.

17. The apparatus of claim 1, wherein the one or more first spiral coils and the one or more second spiral coils are connected to form a single current loop.

18. The apparatus of claim 1, wherein the one or more first spiral coils and the one or more second spiral coils comprise different materials.

19. The apparatus of claim 1, wherein the one or more first spiral coils and the one or more second spiral coils are between about 10 μ ι η to about 10m in diameter.

20. The apparatus of claim 1, wherein the coil assembly further comprises one or more electronic components for tuning the electromagnetic field gradient.

21. The apparatus of claim 20, wherein the one or more electronic components comprise at least one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

22. The apparatus of claim 20, wherein the one or more electronic components for tuning comprise at least one of a dielectric, a conductive metal, a metamaterial, or a magnetic metal.

23. The apparatus of claim 22, wherein tuning the electromagnetic field gradient comprises changing the current or changing a physical location of the one or more electronic components.

24. The apparatus of claim 1, wherein the coil assembly is cryogenically cooled to reduce electrical resistance and increase efficiency.

25. The apparatus of claim 1, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is at least partially disposed outside of the coil assembly region.

26. A method of using a magnetic imaging apparatus, comprising:

providing a power supply;

providing a single-sided gradient coil set connected to the power supply, the coil set having an aperture,

wherein the coil set comprises one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture; and

switching on the power supply to flow current through the one or more first helical coils and the one or more second helical coils to generate an electromagnetic field gradient that is projected away from the coil set and into an imaging region of the magnetic field imaging device.

27. The method of claim 26, wherein the electromagnetic field gradient is greater than about 5 mT.

28. The method of claim 26, wherein the electromagnetic field gradient has a rise time of less than about 10 μ β.

29. The method of claim 26, wherein the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

30. The method of claim 29, further comprising:

tuning the electromagnetic field gradient by changing the current or by changing one of a physical characteristic or a position of the one or more electronic components.

31. The method of claim 26, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside of the coil assembly region.

32. A magnetic imaging apparatus comprising:

a power supply for supplying a current; and

a single-sided gradient coil set connected to the power supply, wherein the coil set is configured to generate an electromagnetic field gradient having a rise time of less than about 10 μ β and the electromagnetic field gradient is configured to project away from the coil set and into an imaging region of the magnetic imaging device.

33. The apparatus of claim 32, wherein the coil assembly further comprises:

pores, and

one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture.

34. The apparatus of claim 32, wherein the coil assembly is non-planar and oriented to partially surround the imaging region.

35. The apparatus of claim 33, wherein the one or more first spiral coils and the one or more second spiral coils are non-planar with respect to the aperture and mirror each other with respect to the aperture.

36. The apparatus of claim 32, wherein the electromagnetic field gradient is substantially uniform in the imaging region.

37. The apparatus of claim 32, wherein the electromagnetic field gradient is greater than about 5 mT.

38. The apparatus of claim 33, wherein the one or more first spiral coils comprise at least two first spiral coils having at least two different diameters.

39. The apparatus of claim 38, wherein the one or more second spiral coils comprise at least two second spiral coils having at least two different diameters.

40. The apparatus of claim 33, wherein the electrical current is configured to flow through the one or more first helical coils in alternating directions.

41. The apparatus of claim 40, wherein the electrical current is configured to flow through the one or more second helical coils in alternating directions to minimize a rise time of the electromagnetic field gradient.

42. The apparatus of claim 33, wherein a primary first spiral coil of the one or more first spiral coils is configured to create a first large primary electromagnetic field gradient and a secondary first spiral coil of the one or more first spiral coils is configured to create a first small secondary electromagnetic field gradient to provide adjustment of the first large primary electromagnetic field gradient.

43. The apparatus of claim 42, wherein a primary second spiral coil of the one or more second spiral coils creates a second large primary electromagnetic field gradient and a secondary second spiral coil of the one or more second spiral coils is configured to create a second small secondary electromagnetic field gradient to provide adjustment of the second large primary electromagnetic field gradient.

44. The apparatus of claim 33, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil cause the current to flow through them in opposite directions.

45. The apparatus of claim 44, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil cause the current to flow through them in opposite directions.

46. The apparatus of claim 33, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil overlap by up to 50% of the respective coils to generate a more parallel first electromagnetic field gradient.

47. The apparatus of claim 46, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil overlap by up to 50% of the respective coils to generate a more parallel second electromagnetic field gradient.

48. The apparatus of claim 33, wherein the one or more first spiral coils and the one or more second spiral coils are connected to form a single current loop.

49. The apparatus of claim 33, wherein the one or more first spiral coils and the one or more second spiral coils comprise different materials.

50. The apparatus of claim 33, wherein the one or more first helical coils and the one or more second helical coils have a diameter between about 10 μ ι η and about 10 m.

51. The apparatus of claim 32, wherein the coil assembly further comprises one or more electronic components for tuning the electromagnetic field gradient.

52. The apparatus of claim 51, wherein the one or more electronic components comprise at least one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

53. The apparatus of claim 51, wherein the one or more electronic components for tuning comprise at least one of a dielectric, a conductive metal, a metamaterial, or a magnetic metal.

54. The apparatus of claim 53, wherein tuning the electromagnetic field gradient comprises changing the current or changing a physical location of the one or more electronic components.

55. The apparatus of claim 32, wherein the coil assembly is cryogenically cooled to reduce electrical resistance and increase efficiency.

56. The apparatus of claim 33, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is at least partially disposed outside of the coil assembly region.

57. A method of using a magnetic imaging apparatus, comprising:

providing a power supply;

providing a set of single-sided gradient coils connected to the power supply;

switching on the power supply to cause current to flow through the coil assembly;

generating an electromagnetic field gradient having a rise time of less than about 10 μ s; and

projecting the electromagnetic field gradient away from the coil assembly and into an imaging region of the magnetic imaging device.

58. The method of claim 57, wherein the electromagnetic field gradient is greater than about 5 mT.

59. The method of claim 57, wherein the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

60. The method of claim 59, further comprising:

tuning the electromagnetic field gradient by changing the current or by changing one of a physical characteristic or a position of the one or more electronic components.

61. The method of claim 57, wherein the coil assembly further comprises:

pores, and

one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture.

62. The method of claim 61, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside of the coil assembly region.

Background

Magnetic Resonance Imaging (MRI) systems have focused primarily on the use of closed profiles. Such contouring includes surrounding the imaging region with materials and imaging system components that generate the electromagnetic field. A typical MRI system includes a cylindrical bore magnet in which a patient is placed within a tube of the magnet for imaging. Components such as Radio Frequency (RF) Transmit (TX), RF Receive (RX) coils, and electromagnetic gradient generation coils are then placed on multiple sides of the patient to effectively surround the patient to perform imaging.

Typically, electromagnetic gradient generating coils are large and completely surround the field of view (i.e., the imaging region) to create linear and monotonic magnetic field gradients throughout the field of view. In most current MRI systems, the placement of components actually surrounds the patient, severely limiting patient movement and sometimes can cause additional burden during positioning or movement of the patient into and out of the imaging region. Therefore, there is a need to provide modern imaging configurations in next generation MRI systems to further alleviate the above-mentioned problems with patient comfort and burdensome limitations.

Disclosure of Invention

At least one aspect of the present disclosure relates to a magnetic imaging apparatus. The device includes: a power supply for supplying a current; and a single-sided gradient coil set connected to a power supply. According to various embodiments, the coil assembly includes an aperture. According to various embodiments, the coil assembly further comprises one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture. According to various embodiments, the first location is opposite the second location with respect to the aperture. In some implementations of the apparatus, the coil set is configured to receive current through the one or more first helical coils and the one or more second helical coils to generate an electromagnetic field gradient configured to project away from the coil set and into an imaging region of the magnetic imaging apparatus.

According to various embodiments, the coil assembly is non-planar and is oriented to partially surround the imaging region. According to various embodiments, the one or more first helical coils and the one or more second helical coils are non-planar with respect to the aperture and mirror each other with respect to the aperture.

According to various embodiments, the electromagnetic field gradient is substantially uniform in the imaging region. According to various embodiments, the electromagnetic field gradient is greater than about 5 mT. According to various embodiments, the electromagnetic field gradient has a rise time of less than about 10 μ s.

According to various embodiments, the one or more first spiral coils comprise at least two first spiral coils having at least two different diameters. According to various embodiments, the one or more second spiral coils comprise at least two second spiral coils having at least two different diameters.

In some implementations of the apparatus, the current flows through the one or more first helical coils in alternating directions to minimize a rise time of the electromagnetic field gradient.

According to various embodiments, the current flows through the one or more second helical coils in alternating directions to minimize the rise time of the electromagnetic field gradient.

According to various embodiments, a primary first-spiral coil of the one or more first-spiral coils is configured to create a first large primary electromagnetic field gradient, and a secondary first-spiral coil of the one or more first-spiral coils is configured to create a first small secondary electromagnetic field gradient to provide adjustment of the first large primary electromagnetic field gradient. According to various embodiments, a primary second helical coil of the one or more second helical coils creates a second large primary electromagnetic field gradient and a secondary second helical coil of the one or more second helical coils creates a second small secondary electromagnetic field gradient to provide adjustment of the second large primary electromagnetic field gradient.

According to various embodiments, a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil cause current to flow through them in opposite directions. According to various embodiments, a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil cause current to flow through them in opposite directions.

According to various embodiments, a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil overlap by up to 50% of the respective coils to generate a more parallel first electromagnetic field gradient. According to various embodiments, a primary second helical coil of the one or more second helical coils and a secondary second helical coil of the one or more second helical coils adjacent to the primary second helical coil overlap by up to 50% of the respective coils to generate a more parallel second electromagnetic field gradient.

According to various embodiments, the one or more first spiral coils and the one or more second spiral coils are connected to form a single current loop. According to various embodiments, the one or more first spiral coils and the one or more second spiral coils comprise different materials.

According to various embodiments, the one or more first spiral coils and the one or more second spiral coils have a diameter between about 10 μm and about 10 m.

According to various embodiments, the coil assembly further comprises one or more electronic components for adjusting the electromagnetic field gradient. According to various embodiments, the one or more electronic components comprise at least one PIN diode, mechanical relay, solid state relay, or MEMS switch. According to various embodiments, the one or more electronic components for tuning comprise at least one of a conductive metal, a metamaterial, or a magnetic metal. According to various embodiments, tuning the electromagnetic field gradient includes changing a current or changing a physical location of one or more electronic components.

According to various embodiments, the coil assembly is cryogenically cooled to reduce electrical resistance and improve efficiency.

According to various embodiments, the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside the coil assembly region.

At least one aspect of the present disclosure relates to a method of using a magnetic imaging device. The method includes providing a power supply and providing a single-sided gradient coil set connected to the power supply. According to various embodiments, the coil assembly includes an aperture. According to various embodiments, the coil set includes one or more first spiral coils at a first location relative to the aperture and one or more second spiral coils at a second location relative to the aperture. According to various embodiments, the first location is opposite the second location with respect to the aperture.

According to various embodiments, the method includes switching on a power supply to flow current through the one or more first helical coils and the one or more second helical coils to generate electromagnetic field gradients that project away from the coil sets and into an imaging region of the magnetic field imaging device.

According to various embodiments, the electromagnetic field gradient is greater than about 5 mT. According to various embodiments, the electromagnetic field gradient has a rise time of less than about 10 μ s.

According to various embodiments, the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch. According to various embodiments, the method further comprises tuning the electromagnetic field gradient by changing one of a current or by changing a physical property or position of the one or more electronic components.

According to various embodiments, the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside the coil assembly region.

At least one aspect of the present disclosure relates to a magnetic imaging apparatus. The device includes: a power supply for supplying a current; and a single-sided gradient coil set connected to the power supply, wherein the coil set is configured to generate electromagnetic field gradients having a rise time of less than about 10 μ β, and the electromagnetic field gradients are configured to project away from the coil set and into an imaging region of the magnetic imaging device.

According to various embodiments, the coil assembly further comprises: the system includes an aperture, and one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture.

According to various embodiments, the coil assembly is non-planar and is oriented to partially surround the imaging region. According to various embodiments, the one or more first helical coils and the one or more second helical coils are non-planar with respect to the aperture and mirror each other with respect to the aperture.

According to various embodiments, the electromagnetic field gradient is substantially uniform in the imaging region. According to various embodiments, the electromagnetic field gradient is greater than about 5 mT.

According to various embodiments, the one or more first spiral coils comprise at least two first spiral coils having at least two different diameters. According to various embodiments, the one or more second spiral coils comprise at least two second spiral coils having at least two different diameters.

In some implementations of the apparatus, the current flows through the one or more first helical coils in alternating directions to minimize a rise time of the electromagnetic field gradient.

According to various embodiments, the current flows through the one or more second helical coils in alternating directions to minimize the rise time of the electromagnetic field gradient.

According to various embodiments, a primary first-spiral coil of the one or more first-spiral coils is configured to create a first large primary electromagnetic field gradient, and a secondary first-spiral coil of the one or more first-spiral coils is configured to create a first small secondary electromagnetic field gradient to provide adjustment of the first large primary electromagnetic field gradient. According to various embodiments, a primary second helical coil of the one or more second helical coils creates a second large primary electromagnetic field gradient and a secondary second helical coil of the one or more second helical coils creates a second small secondary electromagnetic field gradient to provide adjustment of the second large primary electromagnetic field gradient.

According to various embodiments, a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil cause current to flow through them in opposite directions. According to various embodiments, a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil cause current to flow through them in opposite directions.

According to various embodiments, a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil overlap by up to 50% of the respective coils to generate a more parallel first electromagnetic field gradient. According to various embodiments, a primary second helical coil of the one or more second helical coils and a secondary second helical coil of the one or more second helical coils adjacent to the primary second helical coil overlap by up to 50% of the respective coils to generate a more parallel second electromagnetic field gradient.

According to various embodiments, the one or more first spiral coils and the one or more second spiral coils are connected to form a single current loop. According to various embodiments, the one or more first spiral coils and the one or more second spiral coils comprise different materials.

According to various embodiments, the one or more first spiral coils and the one or more second spiral coils have a diameter between about 10 μm and about 10 m.

According to various embodiments, the coil assembly further comprises one or more electronic components for adjusting the electromagnetic field gradient. According to various embodiments, the one or more electronic components comprise at least one PIN diode, mechanical relay, solid state relay, or MEMS switch. According to various embodiments, the one or more electronic components for tuning comprise at least one of a conductive metal, a metamaterial, or a magnetic metal. According to various embodiments, tuning the electromagnetic field gradient includes changing a current or changing a physical location of one or more electronic components.

According to various embodiments, the coil assembly is cryogenically cooled to reduce electrical resistance and improve efficiency.

According to various embodiments, the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside the coil assembly region.

At least one aspect of the present disclosure relates to a method of using a magnetic imaging device. The method includes providing a power supply and providing a single-sided gradient coil set connected to the power supply. The method includes switching on a power supply to cause a current to flow through the coil assembly. The method includes generating an electromagnetic field gradient having a rise time of less than about 10 μ s. The method includes projecting electromagnetic field gradients away from the coil assembly and into an imaging region of a magnetic imaging device.

According to various embodiments, the electromagnetic field gradient is greater than about 5 mT.

According to various embodiments, the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch. According to various embodiments, the method further comprises tuning the electromagnetic field gradient by changing one of a current or by changing a physical property or position of the one or more electronic components.

According to various embodiments, the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside the coil assembly region.

These and other aspects and implementations are discussed in detail below. The foregoing information and the following detailed description include illustrative examples of various aspects and implementations, and provide an overview or framework for understanding the nature and character of the claimed aspects and implementations. The accompanying drawings provide an illustration and a further understanding of the various aspects and implementations, and are incorporated in and constitute a part of this specification.

Drawings

The drawings are not intended to be drawn to scale. Like reference numbers and designations in the various drawings indicate like elements. For purposes of clarity, not every component may be labeled in every drawing. In the drawings:

FIG. 1 is a schematic diagram of an implementation of a magnetic imaging apparatus according to various embodiments;

FIG. 2 is a schematic diagram of an implementation of a single-sided gradient coil set, in accordance with various embodiments;

FIG. 3 is a schematic diagram of an implementation of a single-sided gradient coil set, in accordance with various embodiments;

FIG. 4 is a schematic diagram of an implementation of a single-sided gradient coil set, in accordance with various embodiments.

FIG. 5 is a flow diagram of a method for using a magnetic imaging device, according to various embodiments.

FIG. 6 is a flow diagram of another method for using a magnetic imaging device, in accordance with various embodiments.

Detailed Description

Typical electromagnetic gradient coil configurations of MRI systems are large and generally surround a field of view, i.e., an imaging region. In particular, the coils used to generate the gradient magnetic fields for spatial encoding during magnetic imaging are typically large and are usually placed on multiple sides of the patient. Gradient magnetic field coils are typically constructed in a curved fingerprint configuration that forms a cylindrical outer shape. The gradient magnetic field coils are designed such that the generated magnetic field is linear over the region of interest (i.e., the imaging region) in order to create a direct mathematical reconstruction of the MRI image. For a typical MRI system, the more linear the gradient magnetic field in the imaging region, the more coils surround the patient. Therefore, the gradient magnetic field coils are specifically designed to surround the patient. However, this configuration of gradient magnetic field coils fails when the appearance is modernized into a single-sided MRI system where surrounding the patient is no longer an option.

To further improve patient comfort and reduce the heavy movement limitations of current MRI systems, single-sided MRI systems have been developed. The disclosure described herein relates generally to magnetic imaging devices for single-sided MRI systems and applications thereof. In particular, the described technology relates to a magnetic imaging apparatus having a single-sided gradient coil set including a plurality of gradient magnetic field spiral coils configured to operate in a single-sided MRI system. As described herein, the disclosed single-sided MRI system may be configured such that the patient is covered on one side by the electromagnetic field generating material and imaging system components, but is not completely enclosed. The configurations described herein provide less restriction to patient movement while reducing unnecessary burden during positioning and/or removal of the patient from the MRI system. In other words, by placing the single-sided gradient coil set on only one side of the patient, the patient does not feel trapped in the MRI system.

The techniques disclosed herein include a new configuration of a single-sided gradient coil set, and a method of generating spatially varying gradient magnetic fields within an imaging region (i.e., a region of interest) at a distance outwardly away from the single-sided gradient coil set. A single-sided gradient coil set as described herein includes one or more coil configurations that generate a near-linear field away from the coil set itself. For imaging in a single-sided MRI system, the disclosed configuration aims to generate a near-linear gradient field that projects outward and between the coil sets, since the coils can no longer surround the patient. In other words, for a gradient coil set to operate in a single-sided MRI system, the gradient magnetic fields used for imaging must be generated remotely from the coil set itself. To project the field out and away from the single-sided gradient coil set, the disclosed coil configuration includes differently sized coils arranged in groups or in different arrangements.

In various implementations as described herein, a single-sided gradient coil set may be configured with currents flowing in alternating directions in different helical coils or different helical coil sets to minimize the rise time of the gradient magnetic field and generate a spatially varying magnetic field within the remotely projected region of interest. In various implementations as disclosed herein, the linearity of the magnetic gradient field is sufficient for the single-sided nature of the gradient magnetic field system. Furthermore, the coil set configuration as disclosed herein is intended to generate gradient magnetic fields that can rise rapidly to improve scan time, spatial resolution and reduce biological effects in the resulting images. Possible biological effects include peripheral nerve stimulation from rapidly changing electromagnetic fields or heating caused by elevated coil temperatures during operation.

FIG. 1 shows a schematic diagram of an example implementation of a magnetic imaging apparatus 100, in accordance with various embodiments. As shown in FIG. 1, the apparatus 100 includes a single-sided gradient coil set 120 configured to project gradient magnetic fields outwardly away from the coil set 120 and within a field of view 130. In various implementations, the field of view 130 is a region of interest for magnetic resonance imaging (i.e., an imaging region) in which the patient resides. Since the patient resides in a field of view 130 remote from the coil assembly 120, the apparatus 100 is suitable for use in a single-sided MRI system.

As shown, the coil set 120 includes various sizes of spiral coils in respective sets of spiral coils 140a, 140b, 140c, and 140d (collectively, "spiral coils 140"). Each set of spiral coils 140 includes at least one spiral coil and fig. 1 is shown to include 3 spiral coils. According to various embodiments, each of the spiral coils 140 has an electrical contact at its center and an electrical contact output at the outer edges of the spiral coil to form a single operational loop of conductive material that spirals outward from center to outer edge, or vice versa. According to various embodiments, each of the spiral coils 140 has a first electrical contact at a first location of the spiral coil and a second electrical contact at a second location of the spiral coil to form a single operational loop of conductive material from the first location to the second location, and vice versa.

According to various embodiments, the coil assembly 120 has a lateral dimension of between about 0.001mm to about 15 m. In various implementations, the lateral dimension of the coil assembly 120 is between about 0.001m and about 10m, between about 0.01m and about 8m, between about 0.03m and about 6m, between about 0.05m and about 5m, between about 0.1m and about 3m, between about 0.2m and about 2m, between about 0.3m and about 1.5m, between about 0.5m and about 1m, or between about 0.01m and about 3m, including any lateral dimension therebetween.

As shown in fig. 1, the coil assembly 120 further includes an aperture 125 at a center thereof, wherein the helical coil 140 is disposed around the aperture 125. The aperture 125 itself does not contain any coil material therein for generating the magnetic material. The coil assembly 120 further includes an opening 127 on an outer edge of the coil assembly 120, and the helical coil 140 may be disposed to the opening 127. In other words, the aperture 125 and the opening 127 define a boundary of the coil assembly 120 within which the helical coil 140 may be disposed. According to various embodiments, the coil assembly 120 is formed in a bowl shape with a hole in the center.

According to various embodiments, a helical coil 140 is formed across the aperture 125. For example, the helical coil 140a is disposed opposite the helical coil 140c with respect to the aperture 125. Similarly, the helical coil 140b is disposed opposite the helical coil 140d with respect to the aperture 125. According to various embodiments, the spiral coils 140a and 140c are formed to be opposite to each other. According to various embodiments, the spiral coils 140b and 140d are formed to be opposite to each other. According to various embodiments, the helical coils 140 in the coil set 120 shown in fig. 1 are configured to create a spatial encoding in the magnetic gradient fields within the field of view 130.

As shown in fig. 1, by attaching electrical contacts 152 and 154 to one or more of the helical coils 140, the coil assembly 120 is also connected to the power source 150 via the electrical contacts 152 and 154. In various implementations, the electrical contact 152 is connected to one of the spiral coils 140, then the one spiral coil 140 is connected to the other spiral coils 140 in series and/or parallel, and then the other spiral coil 140 is connected to the electrical contact 154 to form a current loop. In various implementations, the spiral coils 140 are all electrically connected in series. In various implementations, the spiral coils 140 are all electrically connected in parallel. In various implementations, some of the spiral coils 140 are electrically connected in series while other spiral coils 140 are electrically connected in parallel. In various implementations, spiral coils 140a are electrically connected in series and spiral coils 140b are electrically connected in parallel. In various implementations, spiral coil 140c is electrically connected in series and spiral coil 140d is electrically connected in parallel. The electrical connections between the spiral coils 140 or each spiral coil in each set of spiral coils 140 may be configured as desired to generate a magnetic field in the field of view 130.

In various implementations, the coil assembly 120 includes a helical coil 140 that is deployed as shown in fig. 1. According to various embodiments, each set of helical coils 140a, 140b, 140c, and 140d is arranged in a row from the aperture 125 to the opening 127 such that each set of helical coils is disposed at an angle of 90 ° apart from each other. According to various embodiments, 140a and 140b are disposed at 45 ° to each other, 140c and 140d are disposed at 45 ° to each other, while 140c is disposed at 135 ° on the other side of 140b, and 140d is disposed at 135 ° on the other side of 140 a. Essentially, any set of spiral coils 140 may be configured in any arrangement for any number "n" of sets of spiral coils 140.

In various implementations, the spiral coils 140 have the same diameter. According to various embodiments, each set of spiral coils 140a, 140b, 140c, and 140d has the same diameter. According to various embodiments, the helical coils 140 have different diameters. According to various embodiments, each set of spiral coils 140a, 140b, 140c, and 140d has a different diameter. According to various embodiments, the spiral coils in each set of spiral coils 140a, 140b, 140c, and 140d have different diameters. According to various embodiments, 140a and 140b have the same first diameter and 140c and 140d have the same second diameter, but the first and second diameters are different.

According to various embodiments, each of the spiral coils 140 has a diameter between about 10 μm and about 10 m. According to various embodiments, each of the spiral coils 140 has a diameter between about 0.001m and about 9m, between about 0.005m and about 8m, between about 0.01m and about 6m, between about 0.05m and about 5m, between about 0.1m and about 3m, between about 0.2m and about 2m, between about 0.3m and about 1.5m, between about 0.5m and about 1m, or between about 0.01m and about 3m, including any diameter therebetween.

According to various embodiments, the spiral coils 140 are connected to form a single circuit loop (or a single current loop). As shown in fig. 1, for example, one of the spiral coils 140 is connected to an electrical contact 152 of the power source 150 and the other spiral coil is connected to an electrical contact 154 such that the spiral coil 140 completes an electrical circuit.

According to various embodiments, the coil assembly 120 generates an electromagnetic field strength (also referred to herein as an "electromagnetic field gradient" or "gradient magnetic field") of between about 1 μ T and about 10T. According to various embodiments, the coil assembly 120 may generate an electromagnetic field strength of between about 100 μ T and about 1T, between about 1mT and about 500mT, or between about 10mT and about 100mT, including any magnetic field strength therebetween. According to various embodiments, the coil assembly 120 may generate an electromagnetic field strength of greater than about 1 μ T, about 10 μ T, about 100 μ T, about 1mT, about 5mT, about 10mT, about 20mT, about 50mT, about 100mT, or about 500 mT.

According to various embodiments, the coil assembly 120 generates an electromagnetic field that pulsates at a rate with a rise time of less than about 100 μ β. According to various embodiments, the coil assembly 120 generates an electromagnetic field that pulsates at a rate with a rise time of less than about 1 μ s, about 5 μ s, about 10 μ s, about 20 μ s, about 30 μ s, about 40 μ s, about 50 μ s, about 100 μ s, about 200 μ s, about 500 μ s, about 1ms, about 2ms, about 5ms, or about 10 ms.

According to various embodiments, the coil assembly 120 is oriented to partially surround the region of interest 130. According to various embodiments, the spiral coils 140 are non-planar with respect to each other. According to various embodiments, the sets of helical coils 140a, 140b, 140c, and 140d are non-planar with respect to each other. In other words, the helical coils 140 and each set of helical coils 140a, 140b, 140c, and 140d form a three-dimensional structure surrounding the region of interest 130 in which the patient resides.

According to various embodiments, the spiral coil 140 comprises the same material. According to various embodiments, the helical coil 140 comprises different materials. According to various embodiments, the spiral coils in group 140a comprise the same first material, the spiral coils in group 140b comprise the same second material, the spiral coils in group 140c comprise the same third material, and the spiral coils in group 140d comprise the same fourth material, but the first, second, third, and fourth materials are different materials. According to various embodiments, the first and second materials are the same material, but the same material is different from the same third and fourth materials. Essentially, any of the spiral coils 140 may be of the same material or different materials, depending on the configuration of the coil assembly 120.

According to various embodiments, the helical coil 140 comprises a hollow or solid tube. According to various embodiments, the helical coil 140 includes one or more windings. According to various embodiments, the winding comprises a stranded wire or any electrically conductive wire. According to various embodiments, the spiral coil 140 comprises copper, aluminum, silver paste, or any highly conductive material including a metal, alloy, or superconducting metal, alloy, or nonmetal. According to various embodiments, the helical coil 140 comprises a metamaterial.

According to various embodiments, the coil assembly 120 includes one or more electronic components for tuning the magnetic field. The one or more electronic components may include PIN diodes, mechanical relays, solid state relays, or switches, including micro-electromechanical system (MEMS) switches. According to various embodiments, the coil may be configured to include any of one or more electronic components along the circuit. According to various embodiments, one or more components may include high permeability alloy (mu metal), dielectric, magnetic, or metallic components that do not actively conduct electricity and may tune the coil. According to various embodiments, the one or more electronic components for tuning comprise at least one of a conductive metal, a metamaterial, or a magnetic metal. According to various embodiments, tuning the electromagnetic field includes changing the current or by changing the physical location of one or more electronic components. According to various embodiments, the coil is cryogenically cooled to reduce resistance and improve efficiency.

FIG. 2 is a schematic diagram of an implementation of a single-sided gradient coil set 200. As shown, the coil assembly 200 includes spiral coils 240a, 240b, and 240c arranged laterally adjacent to one another at spaced apart distances. Although only 3 spiral coils are shown in fig. 2 for illustrative purposes to convey the general concept of spiral coils in coil set 200, this illustration should not limit the techniques as described herein. A current source (not shown) is connected to each spiral coil 240a, 240b and 240c to provide current in directions 250a, 250b and 250c as shown in fig. 2. The directions of current 250a, 250b, and 250c flowing through the spiral coils 240a, 240b, and 240c generate respective magnetic fields 260a, 260b, and 260 c. As shown, the direction, magnitude, uniformity, etc. of each of the magnetic fields 260a, 260b, and 260c generated by the respective spiral coils 240a, 240b, and 240c can be specifically configured to obtain a desired overall electromagnetic field or gradient field distribution.

The configuration shown in fig. 2 may be used to reduce the effects of magnetic field harmonics, for example, by causing the middle spiral coil 240b to flow current in opposite directions of the two other spiral coils 240a and 240 c. According to various embodiments, the spiral coil 240b may be configured to generate most of the magnetic field, while the spiral coils 240a and 240c are configured to correct for harmonics and non-linearities of the magnetic field generated by the spiral coil 240 b. Essentially, any possible configuration may be implemented using the techniques described herein to shape and form the desired electromagnetic fields or field gradients to aid in MRI imaging.

According to various embodiments, the opposite current directions in the spiral coils 240a, 240b, and 240c may help reduce the electromagnetic gradient coil current rise time. According to various embodiments, the electromagnetic field gradient has a rise time of less than about 1 μ s, about 5 μ s, about 10 μ s, about 20 μ s, about 30 μ s, about 40 μ s, about 50 μ s, about 100 μ s, about 200 μ s, about 500 μ s, about 1ms, about 2ms, about 5ms, or about 10 ms.

According to various embodiments, the opposite current direction helps to reduce the coupling inductance between the spiral coils 240a, 240b, and 240 c. According to various embodiments, the coupling inductance between spiral coils 240a, 240b, and 240c is reduced by between about 1% and about 80%, between about 5% and about 60%, between about 10% and about 40%, between about 15% and about 30%, or between about 1% and about 10%, including any range therebetween.

FIG. 3 is a schematic diagram of an implementation of a single-sided gradient coil set 300. As shown, coil set 300 includes spiral coils 340a, 340b, and 340c arranged laterally adjacent to one another such that the spiral coils are in contact. A current source (not shown) is connected to each spiral coil 340a, 340b, and 340c to provide current in directions 350a, 350b, and 350c as shown in fig. 3. The directions of current 350a, 350b, and 350c flowing through the helical coils 340a, 340b, and 340c generate respective magnetic fields 360a, 360b, and 360 c. Similar to the coil set 200 of fig. 2, the amplitude, uniformity, etc. of each of the magnetic fields 360a, 360b, and 360c generated by the respective spiral coils 340a, 340b, and 340c can be specifically configured to obtain a desired overall electromagnetic field or gradient field distribution.

The configuration shown in fig. 3 may also be used to reduce the effects of magnetic field harmonics discussed with respect to fig. 2. According to various embodiments, the opposite current direction in the spiral coils 340a, 340b, and 340c may help to reduce the electromagnetic gradient coil current rise time. Since the spiral coils 340a, 340b, and 340c are closer to each other than the spiral coils 240a, 240b, and 240c, the reduction effect is more enhanced in terms of reduction of the gradient coil current rise time. According to various embodiments, the rise time of the electromagnetic field gradient generated by the helical coils 340a, 340b, and 340c is less than about 0.1 μ s, about 0.5 μ s, about 1 μ s, about 5 μ s, about 10 μ s, about 20 μ s, about 30 μ s, about 40 μ s, about 50 μ s, about 100 μ s, about 200 μ s, about 500 μ s, about 1ms, about 2ms, about 5ms, or about 10 ms.

According to various embodiments, the opposite current direction helps to reduce the coupling inductance between the spiral coils 340a, 340b, and 340 c. In essence, the opposite current direction of the closer spiral coils compared to spiral coils 240a, 240b, and 240c may help to further reduce the coupling inductance between spiral coils 340a, 340b, and 340 c. According to various embodiments, the coupling inductance between spiral coils 340a, 340b, and 340c is reduced by between about 1% and about 90%, between about 5% and about 60%, between about 10% and about 40%, between about 15% and about 30%, or between about 1% and about 10%, including any range therebetween.

FIG. 4 is a schematic diagram of an implementation of a single-sided gradient coil set 400. As shown, the coil assembly 400 includes spiral coils 440a, 440b, and 440c that overlap each other. A current source (not shown) is connected to each spiral coil 440a, 440b and 440c to provide current in the same direction 450a, 450b and 450c as shown in fig. 4. The same current directions 450a, 450b, and 450c flowing through the spiral coils 440a, 440b, and 440c generate magnetic fields 460a, 460b, and 460c of the same direction. Similar to the coil assembly 200 of fig. 2 and the coil assembly 300 of fig. 3, the amplitude, uniformity, etc. of each of the magnetic fields 460a, 460b, and 460c generated by the respective spiral coils 440a, 440b, and 440c may be specifically configured to obtain a desired overall electromagnetic field or gradient field distribution. However, the same direction of the overlapping spiral coils 440a, 440b, and 440c magnetically decouples the spiral coils 440a, 440b, and 440 c. The overlapping of spiral coils 440a, 440b, and 44 allows the magnetic field within one coil (e.g., spiral coil 440b) to increase the magnetic field within the overlapping coils (e.g., spiral coils 440a and 440c), and vice versa.

FIG. 5 is a flow diagram of a method S100 for using a magnetic imaging device, in accordance with various embodiments. According to various embodiments, the method S100 includes providing power at step S110.

According to various embodiments, the method S100 includes providing a single-sided gradient coil set connected to a power supply at step S120. According to various embodiments, the coil assembly includes an aperture and one or more first spiral coils at a first location relative to the aperture and one or more second spiral coils at a second location relative to the aperture. According to various embodiments, the first location is opposite the second location relative to the aperture.

As shown in fig. 5, the method S100 includes, at step S130, turning on a power source to flow a current through one or more first spiral coils and one or more second spiral coils. According to various embodiments, the current flow generates electromagnetic field gradients that project away from the coil assembly and into an imaging region of the magnetic imaging device.

According to various embodiments, the electromagnetic field gradient is greater than about 5 mT. According to various embodiments, the electromagnetic field gradient has a rise time of less than about 10 μ s. According to various embodiments, the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

According to various embodiments, the method S100 optionally comprises, at step S140, tuning the electromagnetic field gradient by changing one of the current or by changing a physical property or position of the one or more electronic components.

According to various embodiments, the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside the coil assembly region.

FIG. 6 is a flow diagram of a method S200 for using a magnetic imaging device, in accordance with various embodiments. According to various embodiments, the method S200 includes providing power at step S210.

According to various embodiments, the method S200 includes providing a single-sided gradient coil set connected to a power supply at step S220.

As shown in fig. 6, method S200 includes turning on the power to flow current through the coil assembly at step S230.

According to various embodiments, method S200 includes generating an electromagnetic field gradient having a rise time of less than about 10 μ β at step S240.

According to various embodiments, the method S200 includes projecting electromagnetic field gradients away from the coil assembly and into an imaging region of the magnetic imaging device at step S250.

According to various embodiments, the electromagnetic field gradient is greater than about 5 mT. According to various embodiments, the electromagnetic field gradient has a rise time of less than about 10 μ s. According to various embodiments, the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

According to various embodiments, the method S200 optionally includes, at step S260, adjusting the electromagnetic field gradient by changing the current or by changing one of a physical characteristic or a position of the one or more electronic components.

According to various embodiments, the coil assembly further comprises an aperture and one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture. According to various embodiments, the first location is opposite the second location with respect to the aperture.

According to various embodiments, the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is disposed at least partially outside the coil assembly region.

Description of the preferred embodiments

1. A magnetic imaging apparatus comprising: a power supply for supplying a current; and a single-sided gradient coil set connected to the power supply, the coil set having an aperture, wherein the coil set includes one or more first spiral coils at a first location relative to the aperture and one or more second spiral coils at a second location relative to the aperture, the first location opposite the second location relative to the aperture, and wherein the coil set is configured to receive current through the one or more first spiral coils and the one or more second spiral coils, thereby generating an electromagnetic field gradient configured to project away from the coil set and into an imaging region of the magnetic imaging device.

2. The apparatus of embodiment 1, wherein the coil assembly is non-planar and oriented to partially surround the imaging region.

3. The apparatus of any of embodiments 1-2, wherein the one or more first helical coils and the one or more second helical coils are non-planar with respect to the aperture and mirror each other with respect to the aperture.

4. The apparatus of any of embodiments 1-3, wherein the electromagnetic field gradient is substantially uniform in the imaging region.

5. The apparatus of any of embodiments 1-4, wherein the electromagnetic field gradient is greater than about 5 mT.

6. The apparatus of any of embodiments 1-5, wherein the electromagnetic field gradient has a rise time of less than about 10 μ β.

7. The apparatus of any of embodiments 1-6, wherein the one or more first helical coils comprise at least two first helical coils having at least two different diameters.

8. The apparatus of embodiment 7, wherein the one or more second helical coils comprise at least two second helical coils having at least two different diameters.

9. The apparatus of any of embodiments 1-8, wherein the electrical current is configured to flow through the one or more first helical coils in alternating directions.

10. The apparatus of embodiment 9, wherein the electrical current is configured to flow through the one or more second helical coils in alternating directions to minimize a rise time of the electromagnetic field gradient.

11. The apparatus of any of embodiments 1-10, wherein a primary first spiral coil of the one or more first spiral coils is configured to create a first large primary electromagnetic field gradient and a secondary first spiral coil of the one or more first spiral coils is configured to create a first small secondary electromagnetic field gradient to provide adjustment of the first large primary electromagnetic field gradient.

12. The apparatus of embodiment 11, wherein a primary second spiral coil of the one or more second spiral coils creates a second large primary electromagnetic field gradient and a secondary second spiral coil of the one or more second spiral coils is configured to create a second small secondary electromagnetic field gradient to provide adjustment of the second large primary electromagnetic field gradient.

13. The apparatus of any of embodiments 1-12, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil cause the current to flow through them in opposite directions.

14. The apparatus of embodiment 13, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil cause the current to flow through them in opposite directions.

15. The apparatus of any of embodiments 1-14, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil overlap by up to 50% of the respective coils to generate a more parallel first electromagnetic field gradient.

16. The apparatus of embodiment 15, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil overlap by up to 50% of the respective coils to generate a more parallel second electromagnetic field gradient.

17. The apparatus of any of embodiments 1-16, wherein the one or more first helical coils and the one or more second helical coils are connected to form a single current loop.

18. The apparatus of any of embodiments 1-17, wherein the one or more first helical coils and the one or more second helical coils comprise different materials.

19. The device of any one of embodiments 1-18, wherein the one or more first helical coils and the one or more second helical coils have a diameter between about 10 μ ι η and about 10 m.

20. The apparatus of any of embodiments 1-19, wherein the coil assembly further comprises one or more electronic components for tuning the electromagnetic field gradient.

21. The apparatus of embodiment 20, wherein the one or more electronic components comprise at least one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

22. The apparatus of any of embodiments 1-21, wherein the one or more electronic components for tuning comprise at least one of a dielectric, a conductive metal, a metamaterial, or a magnetic metal.

23. The apparatus of embodiment 22, wherein tuning the electromagnetic field gradient comprises changing the current or changing a physical location of the one or more electronic components.

24. The apparatus of any of embodiments 1-23, wherein the coil assembly is cryogenically cooled to reduce electrical resistance and improve efficiency.

25. The apparatus of any of embodiments 1-24, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is at least partially disposed outside of the coil assembly region.

26. A method of using a magnetic imaging apparatus, comprising: providing a power supply; providing a single-sided gradient coil set connected to the power supply, the coil set having an aperture, wherein the coil set includes one or more first spiral coils at a first location relative to the aperture and one or more second spiral coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture; and switching on the power supply to flow current through the one or more first helical coils and the one or more second helical coils to generate an electromagnetic field gradient that is projected away from the coil set and into an imaging region of the magnetic field imaging device.

27. The method of embodiment 26, wherein the electromagnetic field gradient is greater than about 5 mT.

28. The method of any one of embodiments 26-27, wherein the electromagnetic field gradient has a rise time of less than about 10 μ β.

29. The method of any of embodiments 26-28, wherein the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

30. The method of embodiment 29, further comprising: tuning the electromagnetic field gradient by changing the current or by changing one of a physical characteristic or a position of the one or more electronic components.

31. The method of any of embodiments 26-30, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is at least partially disposed outside of the coil assembly region.

32. A magnetic imaging apparatus comprising: a power supply for supplying a current; and a single-sided gradient coil set connected to the power supply, wherein the coil set is configured to generate an electromagnetic field gradient having a rise time of less than about 10 μ β, and the electromagnetic field gradient is configured to project away from the coil set and into an imaging region of the magnetic imaging device.

33. The apparatus of embodiment 32, wherein the coil assembly further comprises: an aperture, and one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture.

34. The apparatus of any of embodiments 32-33 wherein the coil assembly is non-planar and oriented to partially surround the imaging region.

35. The apparatus of any one of embodiments 33-34, wherein the one or more first helical coils and the one or more second helical coils are non-planar with respect to the aperture and mirror each other with respect to the aperture.

36. The apparatus of any of embodiments 32-35, wherein the electromagnetic field gradient is substantially uniform in the imaging region.

37. The apparatus of any one of embodiments 32 to 36 wherein the electromagnetic field gradient is greater than about 5 mT.

38. The apparatus of any one of embodiments 33-37 wherein the one or more first helical coils comprises at least two first helical coils having at least two different diameters.

39. The apparatus of embodiment 38, wherein the one or more second helical coils comprise at least two second helical coils having at least two different diameters.

40. The apparatus of any one of embodiments 33 to 39 wherein the electrical current is configured to flow through the one or more first helical coils in alternating directions.

41. The apparatus of embodiment 40, wherein the electrical current is configured to flow through the one or more second helical coils in alternating directions to minimize a rise time of the electromagnetic field gradient.

42. The apparatus of any of embodiments 33-41, wherein a primary first spiral coil of the one or more first spiral coils is configured to create a first large primary electromagnetic field gradient and a secondary first spiral coil of the one or more first spiral coils is configured to create a first small secondary electromagnetic field gradient to provide adjustment of the first large primary electromagnetic field gradient.

43. The apparatus of embodiment 42, wherein a primary second spiral coil of the one or more second spiral coils creates a second large primary electromagnetic field gradient and a secondary second spiral coil of the one or more second spiral coils is configured to create a second small secondary electromagnetic field gradient to provide adjustment of the second large primary electromagnetic field gradient.

44. The apparatus of any one of embodiments 33-43 wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil cause the current to flow through them in opposite directions.

45. The apparatus of embodiment 44, wherein a primary second spiral coil of the one or more second spiral coils and a secondary second spiral coil of the one or more second spiral coils adjacent to the primary second spiral coil cause the current to flow through them in opposite directions.

46. The apparatus of any of embodiments 33-45, wherein a primary first spiral coil of the one or more first spiral coils and a secondary first spiral coil of the one or more first spiral coils adjacent to the primary first spiral coil overlap by up to 50% of the respective coils to generate a more parallel first electromagnetic field gradient.

47. The apparatus of embodiment 46, wherein a primary second helical coil of the one or more second helical coils and a secondary second helical coil of the one or more second helical coils adjacent to the primary second helical coil overlap by up to 50% of the respective coils to generate a more parallel second electromagnetic field gradient.

48. The apparatus of any one of embodiments 33-47, wherein the one or more first helical coils and the one or more second helical coils are connected to form a single current loop.

49. The apparatus of any one of embodiments 33-48, wherein the one or more first helical coils and the one or more second helical coils comprise different materials.

50. The device of any one of embodiments 33 to 49, wherein the one or more first helical coils and the one or more second helical coils have a diameter of between about 10 μm and about 10 m.

51. The apparatus of any of embodiments 32-50 wherein the coil assembly further comprises one or more electronic components for tuning the electromagnetic field gradient.

52. The apparatus of embodiment 51 wherein the one or more electronic components comprise at least one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

53. The apparatus of any of embodiments 32-52 wherein the one or more electronic components for tuning comprise at least one of a dielectric, a conductive metal, a metamaterial, or a magnetic metal.

54. The apparatus of any one of embodiments 32-53 wherein tuning the electromagnetic field gradient comprises changing the current or changing a physical location of the one or more electronic components.

55. The apparatus of any one of embodiments 32-54 wherein the coil assembly is cryogenically cooled to reduce electrical resistance and increase efficiency.

56. The apparatus of any of embodiments 33-55, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is at least partially disposed outside of the coil assembly region.

57. A method of using a magnetic imaging apparatus, comprising: providing a power supply; providing a set of single-sided gradient coils connected to the power supply; switching on the power supply to cause current to flow through the coil assembly; generating an electromagnetic field gradient having a rise time of less than about 10 μ s; and projecting the electromagnetic field gradients away from the coil assembly and into an imaging region of the magnetic imaging device.

58. The method of embodiment 57 wherein the electromagnetic field gradient is greater than about 5 mT.

59. The method of any of embodiments 57-58, wherein the coil assembly further comprises one or more electronic components from one of a PIN diode, a mechanical relay, a solid state relay, or a MEMS switch.

60. The method of embodiment 59, further comprising: tuning the electromagnetic field gradient by changing the current or by changing one of a physical characteristic or a position of the one or more electronic components.

61. The method of any of embodiments 57-60, wherein the coil assembly further comprises: an aperture, and one or more first helical coils at a first location relative to the aperture and one or more second helical coils at a second location relative to the aperture, the first location being opposite the second location relative to the aperture.

62. The method of embodiment 61, wherein the coil assembly further comprises an opening opposite the aperture, wherein a region between the aperture and the opening defines a coil assembly region, and wherein the imaging region is at least partially disposed outside of the coil assembly region.

While this specification contains many specific implementation details, these should not be construed as limitations on the scope of any invention or of what may be claimed, but rather as descriptions of features specific to particular implementations of particular inventions. Certain features that are described in this specification in the context of separate implementations can also be implemented in combination in a single implementation. Conversely, various features that are described in the context of a single implementation can also be implemented in multiple implementations separately or in any suitable subcombination. Furthermore, although features may be described above as acting in certain combinations and even initially claimed as such, one or more features from a claimed combination can in some cases be excised from the combination, and the claimed combination may be directed to a subcombination or variation of a subcombination.

Similarly, while operations are depicted in the drawings in a particular order, this should not be understood as requiring that such operations be performed in the particular order shown or in sequential order, or that all illustrated operations be performed, to achieve desirable results. In some cases, multitasking and parallel processing may be advantageous. Moreover, the separation of various system components in the implementations described above should not be understood as requiring such separation in all implementations, and it should be understood that the described program components and systems can generally be integrated into a single software product or packaged into multiple software products.

References to "or" may be construed as inclusive such that any term described using "or" may indicate any single one, more than one, and all of the described terms. The terms "first," "second," "third," and the like, do not necessarily denote any order, but generally are used merely to distinguish one item or element from another.

Various modifications to the implementations described in this disclosure will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other implementations without departing from the spirit or scope of the disclosure. Thus, the claims are not intended to be limited to the implementations shown herein but are to be accorded the widest scope consistent with the present disclosure, the principles and novel features disclosed herein.