阅读说明：本技术 一种缓解化疗引起的手足综合征的冷热双用手套脚套 (Cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy ) 是由 于滢华 于 2021-09-16 设计创作，主要内容包括：本发明涉及医护用品技术领域,具体来说是一种缓解化疗引起的手足综合征的冷热双用手套脚套,包括保护套本体,保护套本体包括背层及掌层；掌层包括由内至外依次设置的：第一基布层,第一基布层紧贴手掌脚掌；第二基布层,其与第一基布层连接,且二者之间设置有第一吸湿性内胆；第三基布层,其与第二基布层连接,且二者之间设置有冷热控制件,冷热控制件包括：冻凝胶袋、制冷件和制热件,制冷件和制热件分别设置于冻凝胶袋的两侧；背层包括：第四基布层和第五基布层,二者之间设置有吸附内胆；第三基布层与第五基布层可拆卸连接。本发明根据手足综合征的作用原理,采用吸附化疗药物和根据化疗药物进行针对性冷热敷设处理,有效减轻了HFS的发生概率。(The invention relates to the technical field of medical supplies, in particular to a cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy, which comprises a protective sleeve body, wherein the protective sleeve body comprises a back layer and a palm layer; the palm layer comprises a layer body and a layer cover, wherein the layer body is sequentially arranged from inside to outside: the first base cloth layer is tightly attached to the palm and the sole; the second base cloth layer is connected with the first base cloth layer, and a first moisture absorption inner container is arranged between the second base cloth layer and the first base cloth layer; third base cloth layer, it is connected with second base cloth layer, and is provided with cold and hot control spare between the two, and cold and hot control spare includes: the refrigerating piece and the heating piece are respectively arranged on two sides of the gel bag; the back layer includes: an adsorption inner container is arranged between the fourth base cloth layer and the fifth base cloth layer; the third base fabric layer is detachably connected with the fifth base fabric layer. According to the invention, the specific cold and hot laying treatment is carried out by adopting the adsorption of the chemotherapeutic drug and the chemotherapeutic drug according to the action principle of the hand-foot syndrome, so that the occurrence probability of HFS is effectively reduced.)

1. A cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy comprises a protective cover body, and is characterized in that the protective cover body comprises a back layer (1) and a palm layer (2);

palm layer (2) includes that from inside to outside sets gradually:

the first base cloth layer (3), the first base cloth layer (3) clings to the palm and the sole of the foot;

the second base cloth layer (4) is connected with the first base cloth layer (3), and a first moisture absorption inner container (5) is arranged between the second base cloth layer and the first base cloth layer;

a third scrim layer (6) connected to the second scrim layer (4) and having a cooling and heating control element disposed therebetween, the cooling and heating control element comprising:

the refrigerator comprises a gel bag (7), a refrigerating piece and a heating piece, wherein the refrigerating piece and the heating piece are respectively arranged on two sides of the gel bag (7);

the backing layer (1) comprises:

the fourth base fabric layer (9), the fourth base fabric layer (9) clings to the back of the hand and the instep;

a fifth base fabric layer (10) which is connected with the fourth base fabric layer (9) and between which an adsorption inner container (11) is arranged;

the third base fabric layer (6) is detachably connected with the fifth base fabric layer (10).

2. The glove, the foot cover for both cold and hot use for relieving hand-foot syndrome caused by chemotherapy according to claim 1, wherein the side wall of the first base fabric layer (3) close to the palm and the sole is detachably connected with a drug treatment layer (12).

3. The cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy according to claim 1, wherein the adsorption inner container (11) is an activated carbon adsorption inner container.

4. The cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy according to claim 3, wherein a second hygroscopic liner (15) is further arranged in the back layer (1), between the fourth base fabric layer (9) and the adsorption liner (11).

5. The glove and foot cover for both cold and hot use for relieving hand-foot syndrome caused by chemotherapy according to claim 4, wherein the second hygroscopic liner (15) is the same as the first hygroscopic liner (5), and the first hygroscopic liner (5) is prepared by the following steps:

(1) dissolving sodium carboxymethylcellulose and preparing into a sodium carboxymethylcellulose solution with the mass fraction of 1%;

(2) adding glycerol into the sodium carboxymethylcellulose solution obtained in the step (1), and freeze-drying until the weight is not changed any more to obtain a first hygroscopic liner;

wherein the mass ratio of the glycerol to the sodium carboxymethyl cellulose is 2-3: 1.

6. The cold and hot dual-purpose glove foot cover for relieving hand-foot syndrome caused by chemotherapy according to claim 1, wherein the first base fabric layer (3) and the fourth base fabric layer (9) are both silk fibers, the second base fabric layer (4) is a waterproof plastic base fabric layer, and the third base fabric layer (6) and the fifth base fabric layer (10) are both polyurethane fiber fabric layers.

7. The glove and foot cover for both cold and hot use for relieving hand-foot syndrome caused by chemotherapy according to claim 1, wherein the gel pack (7) is provided with a temperature sensor (8).

8. The glove and foot cover for both cold and hot use for relieving hand-foot syndrome caused by chemotherapy according to claim 7, wherein the refrigerating piece is a refrigerating piece (14), the heating piece is an electric heating wire (13), the refrigerating piece (14), the electric heating wire (13) and the temperature sensor (8) are respectively electrically connected with a controller, and the controller is electrically connected with a battery.

Technical Field

The invention relates to the technical field of medical supplies, in particular to a cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy.

Background

Chemotherapy is an indispensable part of the treatment of diseases for most tumor patients, but the toxic side effects of such drugs have adverse effects on the life of the patients. Hand-Foot syndrome (HFS) is firstly reported in 1974, and the incidence rate of HFS in chemotherapy patients is high, wherein the incidence rates of HFS triggered by doxorubicin liposome and capecitabine are respectively as high as 40-50% and 50-60%, and the main clinical manifestations are as follows: paresthesia, burning pain and erythema on the border of the hands and feet appear 2 to 12 days after the chemotherapy, and as the course of disease progresses, blisters can appear, further ulcers, desquamation, scabbing and epidermal necrosis appear, the main lesions of the lesions are located in the palmoplantar area, and the dorsum of the hands, the dorsum of the feet, the armpits and the back are affected in more serious patients. HFs caused by patients using taxus drugs are mainly manifested by peripheral neurotoxic symptoms, including numbness, needling sensations, loss of sensation, and the like.

The pathogenesis of hand-foot syndrome caused by doxorubicin liposomes is not clear at present, and the reasons for this are probably related to the following aspects: 1. the dosage of chemotherapeutic drugs is related: such as initial metering, accumulated dose and treatment course dose, the chemotherapy drugs need to reach certain blood concentration for a long time, and the metabolic cycle is long, so the probability of exposing the hand and foot parts to drug toxicity is correspondingly prolonged; 2. the characteristics of the hand and foot parts are as follows: the capillary networks of hands and feet are rich, the mechanical friction frequency is high, and the repeated mechanical friction is easy to cause capillary micro-damage, so that the outward osmosis of the chemotherapy drugs is aggravated, and the generation of HFS is accelerated. Researches show that doxorubicin is excreted through local sweat glands, the small sweat glands at the palmoplantar part are rich in distribution, so that the accumulation of the drug in the area is more easily caused, and the cutin of the hand and foot parts is thicker, so that the drug storage is facilitated, and toxic free radicals and chemical injury are more easily generated. 3. Difference in tissue enzyme distribution: it was found that the proliferation of epidermal basal cells in the palms of the hands is higher than that in the backs of the hands, and thymidine phosphorylase activity is increased, which makes cytotoxic drugs more sensitive to the effects of the palms of the hands. 4. Inflammatory reaction: the chemotherapy drugs induce cells to release inflammatory factors and chemotactic factors, and the released inflammatory factors can increase vascular permeability, so that the skin has inflammatory reactions such as redness, swelling, heating, pain and the like, and moreover, fibrous tissues are damaged to a certain extent, and further HFS is generated. The mechanism of the taxanes to generate HFS is mainly peripheral neuropathy, and the generation reason is mainly autonomic nerve injury caused by chemotherapy drugs, so that a series of symptoms and physical signs appear.

Aiming at the pathogenesis of HFS, besides corresponding drug treatment, the disease can be prevented through physical intervention, the cold compress can contract local blood vessels, reduce oxygen consumption, reduce the arrival of chemotherapy drugs at the tail ends of limbs and reduce the release of inflammatory factors, and researches show that the cold compress is carried out on the areas of hands and feet in the chemotherapy process of patients using doxorubicin hydrochloride lipidosome, so that the incidence rate and the severity of HFS can be reduced. Related researches show that the HFS corresponding symptoms generated by paclitaxel can be relieved by expanding blood vessels through hot compress and reducing the tension degree of muscles.

For breast cancer patients, different chemotherapy schemes applied by stages are different, anthracyclines are required to be used in the early stage of some patients, HFS caused by the medicines can be prevented or reduced in severity degree through cold compress, HFS caused by paclitaxel medicines used in the later stage can be relieved through hot compress, medical appliances specially aiming at the hand-foot syndrome problem are not provided in the chemotherapy process in the prior art, the symptoms of the hand-foot syndrome are gradually highlighted, and discomfort of the patients after chemotherapy is increased; therefore, there is a need for a simple, convenient, economical device for preventing or treating hand-foot syndrome during chemotherapy.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide the cold and hot dual-purpose glove and foot cover for relieving the hand-foot syndrome caused by chemotherapy.

In order to solve the technical problems, the invention adopts the following technical scheme:

a cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy comprises a protective sleeve body, wherein the protective sleeve body comprises a back layer and a palm layer;

the palm layer comprises a layer body and a layer cover, wherein the layer body is sequentially arranged from inside to outside:

the first base cloth layer is tightly attached to the palm and the sole of the foot;

the second base cloth layer is connected with the first base cloth layer, and a first moisture absorption inner container is arranged between the second base cloth layer and the first base cloth layer;

a third base fabric layer connected to the second base fabric layer with a cooling and heating control member disposed therebetween, the cooling and heating control member including:

the refrigerator comprises a gel bag, a refrigerating piece and a heating piece, wherein the refrigerating piece and the heating piece are respectively arranged on two sides of the gel bag;

the backing layer includes:

the fourth base fabric layer is tightly attached to the back of the hand and the instep;

the fifth base fabric layer is connected with the fourth base fabric layer, and an adsorption inner container is arranged between the fifth base fabric layer and the fourth base fabric layer;

the third base fabric layer is detachably connected with the fifth base fabric layer.

Preferably, a drug treatment layer is detachably connected to the side wall of the first base cloth layer close to the palm and the sole of the foot.

Preferably, the adsorption inner container is an activated carbon adsorption inner container.

Preferably, a second hygroscopic liner is further arranged in the back layer and between the fourth base cloth layer and the adsorption liner.

Preferably, the second hygroscopic liner is the same as the first hygroscopic liner, and the first hygroscopic liner is prepared according to the following steps:

(1) dissolving sodium carboxymethylcellulose and preparing into a sodium carboxymethylcellulose solution with the mass fraction of 1%;

(2) adding glycerol into the sodium carboxymethylcellulose solution, and freeze-drying until the weight is not changed any more to obtain a first hygroscopic liner;

wherein the mass ratio of the glycerol to the sodium carboxymethyl cellulose is 2-3: 1.

Preferably, first base cloth layer fourth base cloth layer is the silk fibre, the second base cloth layer is waterproof plastics base cloth layer, the third base cloth layer reaches fifth base cloth layer is the polyurethane fiber cloth layer.

Preferably, a temperature sensor is arranged on the gel pack.

Preferably, the refrigeration piece is the refrigeration piece, the heating piece is electric heating wire, the refrigeration piece electric heating wire reaches temperature sensor respectively with controller electric connection, controller and battery electric connection.

Compared with the prior art, the invention has the beneficial effects that:

1. the invention provides a glove which can be used for cold compress or hot compress according to the types of chemotherapeutic drugs, and provides great convenience for preventing and treating HFS for patients. The cold and hot gloves are in the shape of normal gloves, the content is mainly cryogel, the cold and hot gloves are provided with the refrigerating piece and the heating piece, the refrigerating piece and the heating piece can heat or refrigerate the cryogel through electrifying, and then the cold compress or hot compress of hands and feet can be realized by controlling the temperature change of the cryogel according to the use of chemotherapy drugs.

2. The medical treatment device is provided with the adsorption inner container, the drug treatment layer and the first moisture absorption inner container, wherein the adsorption inner container is used for adsorbing free chemotherapeutic drugs in the air and protecting the back of the hand; the medicine of the medicine processing layer is used for processing the chemotherapy medicine secreted by sweat glands, the first hygroscopic liner and the second hygroscopic liner are both prepared from sodium carboxymethylcellulose and glycerol, the aim of drying hands and feet is achieved, and the adsorption of the chemotherapy medicine on the hands and feet is achieved through the porous structures of the first hygroscopic liner and the second hygroscopic liner.

Drawings

FIG. 1 is a schematic view of the internal structure of a palm layer of a cold-hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy, according to the present invention;

FIG. 2 is a schematic view of the internal structure of the back layer of the cold and hot dual-purpose glove foot cover for relieving hand-foot syndrome caused by chemotherapy according to the present invention;

FIG. 3 is a schematic structural view of the protective cover body of the cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy, which is used as a glove;

FIG. 4 is a side view of the protective cover body of the cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy, which is used as a foot cover;

fig. 5 is a bottom view of the protective cover body of the cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy, which is used as a foot cover.

Description of reference numerals:

1. a back layer; 2. a palm layer; 3. a first base fabric layer; 4. a second scrim layer; 5. a first hygroscopic liner; 6. a third base fabric layer; 7. a gel pack; 8. a temperature sensor; 9. a fourth base fabric layer; 10. a fifth base fabric layer; 11. adsorbing the inner container; 12. a drug treatment layer; 13. an electric heating wire; 14. a refrigeration plate; 15. a second hygroscopic liner.

Detailed Description

The following detailed description of specific embodiments of the invention is provided, but it should be understood that the scope of the invention is not limited to the specific embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention. The experimental methods described in the examples of the present invention are all conventional methods unless otherwise specified.

A cold and hot dual-purpose glove and foot cover for relieving hand-foot syndrome caused by chemotherapy comprises a protective sleeve body, wherein the protective sleeve body comprises a back layer 1 and a palm layer 2, the palm layer 2 is used for being close to a palm and a sole, and the back layer 1 is used for being close to a back of a hand and an instep;

palm layer 2 includes that from interior to exterior sets gradually:

the first base cloth layer 3 is tightly attached to the palm and the sole of the foot;

a second base fabric layer 4 connected to the first base fabric layer 3, and a first moisture-absorbing liner 5 disposed therebetween, wherein the first moisture-absorbing liner 5 is prepared according to the following steps:

(1) dissolving sodium carboxymethylcellulose and preparing into a sodium carboxymethylcellulose solution with the mass fraction of 1%;

(2) adding glycerol into the sodium carboxymethylcellulose solution obtained in the step (1), and freeze-drying until the weight is not changed any more to obtain a first hygroscopic liner;

wherein the mass ratio of the glycerol to the sodium carboxymethyl cellulose is 2-3: 1; the glycerin has the water absorption function, and the first moisture absorption inner container 5 has a porous structure after being frozen and dried, so that the hand and the foot can be dried and chemotherapeutic drugs can be absorbed at the same time; as can be seen, the first hygroscopic liner 5 is prepared from sodium carboxymethylcellulose and glycerol, so that the purpose of drying hands and feet is achieved, and the chemotherapeutic drugs are adsorbed;

a third base cloth layer 6 connected to the second base cloth layer 4 and provided with a cold and hot control member therebetween, the cold and hot control member being used for cold or hot compress according to the kind of the chemotherapy drug, and then alleviating the hand-foot syndrome caused by the chemotherapy, the cold and hot control member comprising:

the refrigerator comprises a gel bag 7, a refrigerating piece and a heating piece, wherein the refrigerating piece and the heating piece are respectively arranged on two sides of the gel bag 7; the refrigeration piece is a refrigeration piece 14, the heating piece is an electric heating wire 13, the gel bag 7 is provided with a temperature sensor 8, the refrigeration piece 14, the electric heating wire 13 and the temperature sensor 8 are respectively electrically connected with a controller, the controller is also connected with an operation panel, the controller is electrically connected with a battery, the controller controls the operation of the refrigeration piece 14 and the electric heating wire 13, the temperature of the gel bag 7 is sensed by the temperature sensor 8, and then the temperature control of the gel bag 7 is realized to adjust the temperature of the palm and the sole;

the backing layer 1 comprises:

the fourth base fabric layer 9, the fourth base fabric layer 9 clings to the back of the hand and the instep;

the fifth base cloth layer 10 is connected with the fourth base cloth layer 9, an adsorption inner container 11 is arranged between the fifth base cloth layer and the fourth base cloth layer, and the adsorption inner container 11 is an activated carbon adsorption inner container and is convenient for adsorbing free chemotherapeutic drugs in air;

the third base fabric layer 6 and the fifth base fabric layer 10 are detachably connected through a zipper, a latch or a magic tape.

Furthermore, a drug treatment layer 12 is detachably connected to the side wall of the first base fabric layer 3 close to the palm and the sole, and the drug of the drug treatment layer 12 is used for treating the chemotherapy drug secreted by the sweat glands.

Further, a second hygroscopic liner 15 is further arranged in the back layer 1 and between the fourth base cloth layer 9 and the adsorption liner 11, the second hygroscopic liner 15 is the same as the first hygroscopic liner 5, and the second hygroscopic liner 15 is used for drying the backs of the hands and the feet on one hand and performing auxiliary adsorption on the chemotherapy drugs dissociated in the air on the other hand, so that the effect of the chemotherapy drugs on the backs of the hands, the feet and the feet is further reduced.

Further, first base cloth layer 3 fourth base cloth layer 9 is the silk fibre, provides comfortable sense of touch for hand and foot, second base cloth layer 4 is waterproof plastic base cloth layer, avoids in the gel moisture gets into to first moisture absorption inner bag 5 after cold and hot in turn in, and then influences the adsorption of first moisture absorption inner bag 5, third base cloth layer 6 reaches fifth base cloth layer 10 is the polyurethane fiber cloth layer for waterproof and ventilative.

The use principle is as follows:

when carrying out the chemotherapy treatment, establish a plurality of protective sheath bodies on hand and foot respectively, then press close to palm and sole with the first base cloth layer 3 on palm layer 2, press close to back of the hand and instep with the fourth base cloth layer 9 of backing layer 1, then according to the kind of the chemotherapy medicine that the patient used, open temperature controller 8 on operating panel, refrigeration piece 14 and electric heating wire 13's control switch, and adjust the temperature through the controller, then make the kind according to the chemotherapy medicine carry out the pertinence, the control of different temperatures, in the chemotherapy, adopt first hygroscopicity inner bag 5, second hygroscopicity inner bag 15 adsorbs with absorption inner bag 11, adopt first hygroscopicity inner bag 5 and second hygroscopicity 15 to dry simultaneously, realize alleviating the purpose of the hand-foot syndrome that the chemotherapy arouses.

It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.