阅读说明：本技术 用于储存生物样本的冰箱 (Refrigerator for storing biological samples ) 是由 胡佳霖 邹富全 周荣 罗有志 江赈宇 于 2021-09-22 设计创作，主要内容包括：本发明属于生物样本低温存储设备技术领域,公开了一种用于储存生物样本的冰箱,包括：侧壁开设有存取口的箱体、封盖存取口的密封门以及均设于箱体内部的样本架总成、冷却元件和样本盒取放机构；箱体内部上下分为顶腔和低温腔；样本架总成包括：沿第一水平方向排成一列的多个样本架；冷却元件和样本架均位于低温腔；处于最外端的两个样本架之一为固定样本架,其余样本架均为活动样本架；固定样本架固定于箱体,活动样本架的顶部悬挂于箱体并连接有驱动其沿第一水平方向往复滑动的驱动机构；驱动机构位于顶腔；样本盒取放机构用于在样本架与存取口之间转移样本盒,样本盒取放机构的顶部悬挂至顶腔并沿第一水平方向滑动设置。(The invention belongs to the technical field of low-temperature storage equipment for biological samples, and discloses a refrigerator for storing biological samples, which comprises: the side wall of the box body is provided with an access opening, the sealing door is used for sealing the access opening, and the sample rack assembly, the cooling element and the sample box taking and placing mechanism are all arranged in the box body; the interior of the box body is divided into a top cavity and a low-temperature cavity from top to bottom; the sample rack assembly includes: a plurality of sample racks arranged in a line in a first horizontal direction; the cooling element and the sample rack are both positioned in the low-temperature cavity; one of the two outermost sample racks is a fixed sample rack, and the other sample racks are movable sample racks; the fixed sample rack is fixed on the box body, and the top of the movable sample rack is suspended on the box body and is connected with a driving mechanism for driving the movable sample rack to slide in a reciprocating manner along a first horizontal direction; the driving mechanism is positioned in the top cavity; the sample box taking and placing mechanism is used for transferring the sample box between the sample rack and the access opening, and the top of the sample box taking and placing mechanism is hung to the top cavity and arranged in a sliding mode along the first horizontal direction.)

1. A refrigerator for storing biological specimens, comprising: the side wall of the box body is provided with an access opening, the sealing door is used for sealing the access opening, and the sample rack assembly, the cooling element and the sample box taking and placing mechanism are all arranged in the box body; the interior of the box body is divided into a top cavity and a low-temperature cavity from top to bottom; the sample rack assembly includes: a plurality of sample racks arranged in a line in a first horizontal direction; the cooling element and the sample rack are both positioned in the low-temperature cavity; the top of the sample rack is hung on the box body and is connected with a driving mechanism for driving the sample rack to slide in a reciprocating manner along a first horizontal direction; the driving mechanism is positioned in the top cavity; the sample box taking and placing mechanism is used for transferring the sample box between the sample rack and the access opening, and the top of the sample box taking and placing mechanism is hung to the top cavity and arranged in a sliding mode along the first horizontal direction.

2. The refrigerator for storing biological samples according to claim 1, wherein at least one of the two outermost sample racks is a fixed sample rack, and the rest sample racks are movable sample racks; the movable sample rack is connected with the driving mechanism.

3. The refrigerator for storing biological samples according to claim 1 or 2, wherein the sample cartridge pick and place mechanism comprises a cross beam, a vertical beam and a sample cartridge gripper; the cross beam is connected with a first driving unit which drives the cross beam to slide along a first horizontal direction; the top of the vertical beam is connected to the cross beam in a sliding mode along a second horizontal direction and is connected with a second driving unit for driving the cross beam to slide in a reciprocating mode, the second horizontal direction is perpendicular to the first horizontal direction, and the top of the vertical beam is connected with a third driving unit for driving the sample box gripper to slide in a reciprocating mode along the vertical direction; the first driving unit, the second driving unit and the third driving unit are all located in the top cavity.

4. The refrigerator for storing biological samples according to claim 3, wherein two longitudinal beams are arranged in the top cavity, and both longitudinal beams are arranged along the first horizontal direction and are respectively positioned at two sides of the sample rack assembly; the two ends of the cross beam are respectively connected with the two longitudinal beams in a sliding manner.

5. The refrigerator for storing biological samples according to claim 4, wherein the sample rack comprises two rack bodies arranged side by side along the second horizontal direction and a connecting plate connected to the lower ends of the two rack bodies together; the second horizontal direction is vertical to the first horizontal direction; an avoidance cavity avoiding the sample box taking and placing mechanism is arranged between the two frame bodies; the top of each frame body is provided with a heat insulation plate and a metal plate; the metal plate is fixedly connected with the frame body, the heat insulation plates are clamped between the metal plate and the frame body, and the heat insulation plates jointly divide the interior of the box body into a top cavity and a low-temperature cavity; the deviating sides of the two metal plates extend outwards and form a suspension connecting part; the two suspension connecting parts of the fixed sample frame are respectively fixed on the two longitudinal beams, and the two suspension connecting parts of the movable sample frame are respectively connected with the two longitudinal beams in a sliding manner.

6. The refrigerator for storing the biological samples according to claim 5, wherein the upper part of the avoiding cavity of the movable sample rack is provided with a heat-insulating cover plate, a gap is formed between the bottom surface of the heat-insulating cover plate and the top surface of the metal plate, the heat-insulating cover plate is connected with a driving device for driving the heat-insulating cover plate to slide in a reciprocating manner along a second horizontal direction, and the heat-insulating cover plate and the heat-insulating plates jointly divide the interior of the refrigerator body into the top cavity and the low-temperature cavity; the driving device is positioned in the low-temperature cavity.

7. The refrigerator for storing the biological samples according to claim 6, wherein a heat-insulating cover plate is arranged at one end of the interior of the refrigerator body, which is far away from the fixed sample rack, and a rotary driving device for driving the heat-insulating cover plate to rotate is connected to one side of the heat-insulating cover plate; the rotation driving device is used for driving the heat-preservation cover plate to rotate so as to close a gap between the sample rack farthest from the fixed sample rack and the box body; the heat-preservation sealing cover plate, the heat-preservation cover plate and the heat-preservation plates jointly divide the interior of the box body into a top cavity and a low-temperature cavity.

8. The refrigerator for storing biological samples according to claim 6, wherein the driving mechanism comprises a driving unit respectively provided at the top of each movable sample rack; each driving unit is used for driving the corresponding movable sample rack to slide along the first horizontal direction.

9. The refrigerator for storing biological samples according to any one of claims 3 to 8, wherein a gap is formed between the bottom of the sample rack and the bottom wall of the interior of the refrigerator body.

10. The refrigerator for storing biological samples according to any one of claims 3 to 8, further comprising a dehumidifying structure; the dehumidification structure includes: the device comprises a closed box, a window frame embedded in an access opening and a condenser arranged in the closed box; the side wall of the access opening is provided with an accommodating cavity for accommodating the closed box; the closed box is respectively provided with an air inlet and an air outlet; a first fan is arranged at the air outlet; the air outlet of the first fan is arranged towards the window frame; the edge of one end of the window frame, which is far away from the sample frame assembly, extends outwards to form an installation flange, and handles are connected to the two sides of the installation flange; a first channel and a second channel are respectively arranged in the window frame; one end of the first channel and one end of the second channel are communicated into the opening of the window frame, and the other end of the first channel and the other end of the second channel are respectively in butt joint with the air inlet and the air outlet; air valves are arranged in the first channel and the second channel; the sealing door is used for sealing the opening of the window frame.

Technical Field

The invention belongs to the technical field of low-temperature storage equipment of biological samples, and particularly relates to a refrigerator for storing biological samples.

Background

The storage capacity of a biological sample library in the prior art is large, the storage temperature is-150 ℃, the application occasions are few, samples such as common vaccines and the like which do not need to be stored at a deep low temperature can meet the storage requirement at-80 ℃, the storage capacity requirement is less compared with that of a large-scale sample library, the storage equipment with the requirement needs to be much smaller in size compared with the large-scale sample library, a freezer type structure is adopted in the prior art to meet the requirement, the sample rack is stored in a storage container at the lower part of the equipment, the sample rack is lifted upwards by a certain height during storage and taking so as to expose the storage container, and a manipulator and the like are used for taking and placing the sample box, so that only the lower space in the equipment can be used for storing the samples, the upper part is used for accommodating the lifted sample rack, the space waste is caused, and the space utilization rate is low.

Disclosure of Invention

In order to solve the above problems of the prior art, the present invention is directed to a refrigerator for storing biological samples.

The technical scheme adopted by the invention is as follows:

a refrigerator for storing biological samples, comprising: the side wall of the box body is provided with an access opening, the sealing door is used for sealing the access opening, and the sample rack assembly, the cooling element and the sample box taking and placing mechanism are all arranged in the box body; the interior of the box body is divided into a top cavity and a low-temperature cavity from top to bottom; the sample rack assembly includes: a plurality of sample racks arranged in a line in a first horizontal direction; the cooling element and the sample rack are both positioned in the low-temperature cavity; the top of the sample rack is hung on the box body and is connected with a driving mechanism for driving the sample rack to slide in a reciprocating manner along a first horizontal direction; the driving mechanism is positioned in the top cavity; the sample box taking and placing mechanism is used for transferring the sample box between the sample rack and the access opening, and the top of the sample box taking and placing mechanism is hung to the top cavity and arranged in a sliding mode along the first horizontal direction.

As a further alternative of the refrigerator for storing biological samples, at least one of the two outermost sample racks is a fixed sample rack, and the rest sample racks are movable sample racks; the movable sample rack is connected with the driving mechanism.

As a further alternative to the refrigerator for storing biological samples, the sample cartridge pick and place mechanism comprises a cross beam, a vertical beam and a sample cartridge gripper; the cross beam is connected with a first driving unit which drives the cross beam to slide along a first horizontal direction; the top of the vertical beam is connected to the cross beam in a sliding mode along a second horizontal direction and is connected with a second driving unit for driving the cross beam to slide in a reciprocating mode, the second horizontal direction is perpendicular to the first horizontal direction, and the top of the vertical beam is connected with a third driving unit for driving the sample box gripper to slide in a reciprocating mode along the vertical direction; the first driving unit, the second driving unit and the third driving unit are all located in the top cavity.

As a further alternative of the refrigerator for storing biological samples, two longitudinal beams are arranged in the top cavity, and both the longitudinal beams are arranged along the first horizontal direction and are respectively positioned at two sides of the sample rack assembly; the two ends of the cross beam are respectively connected with the two longitudinal beams in a sliding manner.

As a further alternative of the refrigerator for storing biological samples, the sample rack comprises two rack bodies arranged side by side along a second horizontal direction and a connecting plate connected to the lower ends of the two rack bodies together; the second horizontal direction is vertical to the first horizontal direction; an avoidance cavity avoiding the sample box taking and placing mechanism is arranged between the two frame bodies; the top of each frame body is provided with a heat insulation plate and a metal plate; the metal plate is fixedly connected with the frame body, the heat insulation plates are clamped between the metal plate and the frame body, and the heat insulation plates jointly divide the interior of the box body into a top cavity and a low-temperature cavity; the deviating sides of the two metal plates extend outwards and form a suspension connecting part; the two suspension connecting parts of the fixed sample frame are respectively fixed on the two longitudinal beams, and the two suspension connecting parts of the movable sample frame are respectively connected with the two longitudinal beams in a sliding manner.

As a further alternative of the refrigerator for storing biological samples, heat-insulating cover plates are arranged above the avoiding cavities of the movable sample rack, gaps are formed between the bottom surfaces of the heat-insulating cover plates and the top surface of the metal plate, the heat-insulating cover plates are connected with a driving device for driving the heat-insulating cover plates to slide in a reciprocating manner along a second horizontal direction, and the heat-insulating cover plates and the heat-insulating plates jointly divide the interior of the refrigerator body into the top cavity and the low-temperature cavity; the driving device is positioned in the low-temperature cavity.

As a further alternative of the refrigerator for storing the biological samples, one end of the interior of the refrigerator body, which is far away from the fixed sample rack, is provided with a heat-insulating sealing cover plate, and one side of the heat-insulating sealing cover plate is connected with a rotary driving device for driving the heat-insulating sealing cover plate to rotate; the rotation driving device is used for driving the heat-preservation cover plate to rotate so as to close a gap between the sample rack farthest from the fixed sample rack and the box body; the heat-preservation sealing cover plate, the heat-preservation cover plate and the heat-preservation plates jointly divide the interior of the box body into a top cavity and a low-temperature cavity.

As a further alternative to the refrigerator for storing biological samples, the drive mechanism includes a drive unit provided at a top of each movable sample rack, respectively; each driving unit is used for driving the corresponding movable sample rack to slide along the first horizontal direction.

As a further alternative to the refrigerator for storing biological samples, there is a gap between the bottom of the sample rack and the bottom wall of the interior of the cabinet.

As a further alternative of the refrigerator for storing biological samples, a dehumidifying structure is further included; the dehumidification structure includes: the device comprises a closed box, a window frame embedded in an access opening and a condenser arranged in the closed box; the side wall of the access opening is provided with an accommodating cavity for accommodating the closed box; the closed box is respectively provided with an air inlet and an air outlet; a first fan is arranged at the air outlet; the air outlet of the first fan is arranged towards the window frame; the edge of one end of the window frame, which is far away from the sample frame assembly, extends outwards to form an installation flange, and handles are connected to the two sides of the installation flange; a first channel and a second channel are respectively arranged in the window frame; one end of the first channel and one end of the second channel are communicated into the opening of the window frame, and the other end of the first channel and the other end of the second channel are respectively in butt joint with the air inlet and the air outlet; air valves are arranged in the first channel and the second channel; the sealing door is used for sealing the opening of the window frame.

The invention has the beneficial effects that:

the sample rack is moved by the driving mechanism, and the sample box taking and placing mechanism is combined to shuttle back and forth between each sample rack and the access port, so that the sample box is taken and placed; the two sample racks only need to leave a space for avoiding the suspension part of the sample box taking and placing mechanism, the space utilization rate is high, and under the same volume, the refrigerator can store more sample boxes.

Drawings

Fig. 1 is a schematic structural view of a refrigerator for storing biological samples according to the present invention.

Fig. 2 is a sectional view a-a in fig. 1.

Fig. 3 is a top structure view of the refrigerator for storing biological samples shown in fig. 1, with a top cover omitted.

Fig. 4 is a schematic structural view of a sample cartridge pick and place mechanism in the refrigerator for storing biological samples shown in fig. 1.

Fig. 5 is a schematic structural view of a sample rack assembly in the refrigerator for storing biological samples shown in fig. 1.

Fig. 6 is a top view of the sample rack assembly in the refrigerator for storing biological samples shown in fig. 1.

Fig. 7 is a schematic structural view of a fixed sample rack in the refrigerator for storing biological samples shown in fig. 1.

Fig. 8 is a schematic structural view of a movable sample rack in the refrigerator for storing biological samples shown in fig. 1.

Fig. 9 is a schematic structural view of a driving unit in the refrigerator for storing biological samples shown in fig. 1.

Fig. 10 is a schematic structural view of a defrosting structure in the refrigerator for storing biological samples shown in fig. 1.

Fig. 11 is a sectional view taken along line B-B in fig. 10.

In the figure: 1-an access port; 2-a box body; 3-sealing the door; 4-a sample rack assembly; 5-a cooling element; 6-a sample box taking and placing mechanism; 7-top cavity; 8-low temperature cavity; 9-a sample rack; 10-a drive mechanism; 11-a cross beam; 12-vertical beams; 13-sample box gripper; 14-a first drive unit; 15-a second drive unit; 16-a third drive unit; 17-a longitudinal beam; 18-a frame body; 19-a connecting plate; 20-avoiding the cavity; 21-an insulation board; 22-metal plate; 23-a suspension connection; 24-a heat preservation cover plate; 25-a drive device; 26-heat preservation cover sealing plate; 27-a rotation drive; 28-a drive unit; 29-a rack; 30-a drive motor; 31-a gear; 32-a dehumidification structure; 33-a closed box; 34-a window frame; 35-a condenser; 36-a first fan; 37-a first heating plate; 38-a first channel; 39-a second channel; 40-a handle; 41-mounting flange; 42-a blast gate; 43-a second fan; 44-second heat patch.

Detailed Description

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the present invention will be briefly described below with reference to the accompanying drawings and the embodiments or the description in the prior art, it is obvious that the following description of the structure of the drawings is only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

The technical solution provided by the present invention will be described in detail by way of embodiments with reference to the accompanying drawings. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto.

In some instances, some embodiments are not described or not in detail, as they are conventional or customary in the art.

Furthermore, the technical features described herein, or the steps of all methods or processes disclosed, may be combined in any suitable manner in one or more embodiments, in addition to the mutually exclusive features and/or steps. It will be readily appreciated by those of skill in the art that the order of the steps or operations of the methods associated with the embodiments provided herein may be varied. Any order in the drawings and examples is for illustrative purposes only and does not imply that a certain order is required unless explicitly stated to be required.

The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The terms "connected" and "coupled" when used in this application, encompass both direct and indirect connections (and couplings) where appropriate and where not necessary contradictory.

As shown in fig. 1 to 11, the refrigerator for storing biological samples of the present embodiment includes: the device comprises a box body 2 with an access port 1 on the side wall, a sealing door 3 for sealing the access port 1, a sample rack assembly 4, a cooling element 5 and a sample box taking and placing mechanism 6 which are all arranged in the box body 2; the interior of the box body 2 is divided into a top cavity 7 and a low-temperature cavity 8 from top to bottom; the specimen holder assembly 4 includes: a plurality of sample racks 9 aligned in a line in the first horizontal direction; the cooling element 5 and the sample rack 9 are both positioned in the low temperature cavity 8; the top of the sample rack is hung on the box body 2 and is connected with a driving mechanism 10 for driving the sample rack to slide in a reciprocating manner along a first horizontal direction; the driving mechanism 10 is positioned in the top cavity 7; the sample box taking and placing mechanism 6 is used for transferring the sample box between the sample rack 9 and the access opening 1, and the top of the sample box taking and placing mechanism 6 is hung to the top cavity 7 and arranged in a sliding mode along the first horizontal direction.

The cooling element 5 may be selected according to the temperature requirements of the stored biological sample, for example, some vaccines may be selected from the cooling systems used in existing household refrigerators, and in one embodiment, the cooling element 5 may be a coil wound around the inner side wall of the case 2, and the coil is filled with a cooling medium.

Assuming that the distance between two inner side walls of the box body 2 in the first horizontal direction is L, the total number of the sample racks is N, and the thickness of each sample rack 9, i.e., the size of the sample rack 9 in the first horizontal direction is D, L > N × D is provided, so that the sample box taking and placing mechanism 6 can place a sample box into each sample rack 9.

The sample racks 9 may all be set as movable sample racks; at least one of the two outermost sample holders 9 may be fixed, and the remaining sample holders 9 may be movable; in the present embodiment, one of the two outermost sample holders 9 is a fixed sample holder, and the others are movable sample holders; the front and back of each sample rack 9 can be grooved to receive a sample box, in which case the sample box gripper 13 adds a rotation about a vertical axis. The sample box can be placed on the front surface or the back surface or both the front surface and the back surface of the sample rack 9 according to requirements in use. In this embodiment, the sample holder 9 is provided with a single-sided slot for placing the sample box.

The access port 1 is arranged on one side close to the fixed sample rack, so that the sample box is convenient to transport, and the space is saved. The sample box pick and place mechanism 6 may be implemented using existing techniques such as a robotic arm, and in one embodiment, the sample box pick and place mechanism 6 may include a cross beam 11, a vertical beam 12, and a sample box gripper 13; the beam 11 is connected with a first driving unit 14 for driving the beam to slide along a first horizontal direction; the top of the vertical beam 12 is connected to the cross beam 11 in a sliding manner along a second horizontal direction and is connected with a second driving unit 15 for driving the cross beam to slide in a reciprocating manner, the second horizontal direction is perpendicular to the first horizontal direction, and the top of the vertical beam 12 is connected with a third driving unit 16 for driving the sample box gripper 13 to slide in a reciprocating manner along a vertical direction; the first drive unit 14, the second drive unit 15 and the third drive unit 16 are all located in the top chamber 7.

The first driving unit 14 and the second driving unit 15 can be realized by using the existing electric sliding table, and the cross beam 11 can be used as a base of the electric sliding table. The third driving unit 16 may be a servo motor, and the servo motor and the sample box gripper 13 may be connected by a flexible transmission mechanism, that is, the servo motor, the vertical beam 12 and the flexible transmission mechanism may form an existing electric sliding table structure.

The first driving unit 14, the second driving unit 15 and the third driving unit 16 are all placed in the top cavity 7, and the temperature of the top cavity 7 is higher than that of the low-temperature cavity 8, so that low-temperature driving components are not needed in the top cavity 7, and the cost is greatly saved; secondly, place drive components and parts in top chamber 7, be more convenient for maintain.

The sample box gripper 13 can be realized by adopting the prior art such as a clamping jaw cylinder.

The sample cartridges may be accessed from any one of the sample racks 9, and the specific process of storing the sample cartridges will be described by taking the sample cartridges from the fixed sample rack as an example:

the driving mechanism 10 drives the movable sample rack to slide along the direction far away from the fixed sample rack, so that an operation cavity is left between the fixed sample rack and the adjacent movable sample rack, the operation cavity is used for avoiding the sample box taking and placing mechanism 6, the fixed sample rack is subjected to sample box storing and placing operation, after the fixed sample rack is full of or completely taken, the driving mechanism 10 drives the two movable sample racks close to the fixed sample rack to slide along the first horizontal direction, the operation cavity is left between the two movable sample racks, the two movable sample racks are subjected to sample box storing and placing operation, and the operation is circulated until all the sample racks 9 are fully stored or completely taken.

In one embodiment, two longitudinal beams 17 are arranged in the top cavity 7, and the two longitudinal beams 17 are both arranged along the first horizontal direction and are respectively positioned at two sides of the sample rack assembly 4; the two ends of the cross beam 11 are respectively connected with the two longitudinal beams 17 in a sliding manner, so that the cross beam 11 moves more smoothly. In one embodiment, the first driving unit 14 may include a servo motor and two flexible transmission mechanisms, the two flexible transmission mechanisms are connected through a cross shaft, and the servo motor is in transmission connection with the cross shaft; two ends of the beam 11 are respectively connected with the flexible elements in the two flexible transmission mechanisms, so that the servo motor can simultaneously drive the two ends of the beam 11 to slide.

In one embodiment, the second driving unit 15 may include a servo motor and a flexible transmission mechanism disposed between the servo motor and the vertical beam 12.

In one embodiment, the sample rack 9 may include two rack bodies 18 arranged side by side in the second horizontal direction and a connection plate 19 connected to the lower ends of the two rack bodies 18 together; the second horizontal direction is vertical to the first horizontal direction; an avoidance cavity 20 for avoiding the sample box taking and placing mechanism 6 is arranged between the two frame bodies 18; the top of each frame body 18 is provided with an insulation board 21 and a metal plate 22; the metal plate 22 is fixedly connected with the frame body 18, the heat insulation plates 21 are clamped between the metal plate 22 and the frame body 18, and the heat insulation plates 21 jointly divide the interior of the box body 2 into a top cavity 7 and a low-temperature cavity 8; the facing sides of both metal plates 22 extend outwards and form a suspension connection 23; the two suspension connecting portions 23 of the fixed sample rack are respectively fixed on the two longitudinal beams 17, and the two suspension connecting portions 23 of the movable sample rack are respectively connected with the two longitudinal beams 17 in a sliding manner.

The frame body 18 may include unit frames arranged in a row along the second horizontal direction, and the unit frames may be implemented by the chinese utility model patent with the publication number CN209757793U, entitled sample cryopreservation frame.

By arranging the avoiding cavity 20, the sample box taking and placing mechanism 6 can move from the avoiding cavity 20 to the two sides of the sample rack 9, the movement path is shortened, and the taking and placing efficiency is improved. The bottoms of the two frame bodies 18 are connected through the connecting plate 19, and the tops of the two frame bodies 18 are respectively connected to the longitudinal beams 17 on the two sides through the two suspension connecting parts 23, so that the rigidity of the sample frame 9 is improved, and the deformation of the sample frame 9 is reduced.

The metal plate 22 may be a conventional steel plate or aluminum alloy plate.

In one embodiment, heat-insulating cover plates 24 are arranged above the avoiding cavities 20 of the movable sample rack, a gap is formed between the bottom surfaces of the heat-insulating cover plates 24 and the top surface of the metal plate 22, the heat-insulating cover plates 24 are connected with a driving device 25 for driving the heat-insulating cover plates to slide in a reciprocating manner along a second horizontal direction, and the heat-insulating cover plates 24 and the heat-insulating plates 21 jointly divide the interior of the box body 2 into a top cavity 7 and a low-temperature cavity 8; the driving device 25 is located in the low temperature chamber 8.

When the sample box is not taken or placed, the driving device 25 drives the heat-insulating cover plate 24 to slide, the top end opening of the avoidance cavity 20 is sealed, low-temperature air in the low-temperature cavity 8 is isolated from being transmitted to the top cavity 7, and the temperature of the top cavity 7 is maintained.

In one embodiment, a heat-insulating sealing cover plate 26 is arranged at one end of the interior of the box body 2 far away from the fixed sample rack, and one side of the heat-insulating sealing cover plate 26 is connected with a rotary driving device 27 for driving the heat-insulating sealing cover plate to rotate; the rotary driving device 27 is used for driving the heat-preservation sealing cover plate 26 to rotate so as to close a gap between the sample rack 9 farthest from the fixed sample rack and the box body 2; the heat-insulating cover plate 26, the heat-insulating cover plate 24 and the heat-insulating plates 21 jointly divide the interior of the box body 2 into a top cavity 7 and a low-temperature cavity 8.

When the sample box is not taken or placed, the vertical beam 12 moves into the avoiding cavity 20 of the fixed sample rack, each sample rack 9 is closed, the heat-insulating cover plate 24 is driven by the rotary driving device 27 to rotate and seal the gap between the sample rack 9 farthest away from the fixed sample rack and the inner side wall of the box body 2, low-temperature air in the low-temperature cavity 8 is further prevented from being transmitted to the top cavity 7, and the temperature of the top cavity 7 is maintained.

In one embodiment, the drive mechanism 10 may include a drive unit 28 disposed at the top of each movable sample rack; each driving unit 28 is used for driving the corresponding movable sample rack to slide along the first horizontal direction. The driving unit 28 may be a telescopic cylinder, that is, a telescopic cylinder is connected between any two adjacent sample racks 9, a piston rod of the telescopic cylinder extends out, and a cavity avoiding the vertical beam 12 and the sample box gripper 13 is left between two adjacent sample racks 9; the piston rod of the telescopic cylinder is retracted, and two adjacent sample racks 9 are closed.

In one embodiment, the drive mechanism 10 may further comprise two racks 29 connected to the two longitudinal beams 17, respectively; both racks 29 are arranged in a first horizontal direction; the driving unit 28 may include a driving motor 30 respectively located at both sides of the top of the movable sample rack and a gear 31 connected to an output end of the driving motor 30; the two gear wheels 31 of each drive unit 28 each mesh with two gear racks 29. The two-side driving motor 30 drives the two-side gear 31 to rotate respectively, so that the movable sample rack can be driven to slide. Both sides are driven simultaneously, and the slip of activity sample frame is more smooth-going.

In one embodiment, there is a gap between the bottom of the sample rack 9 and the bottom wall inside the case 2 to avoid friction between the bottom of the sample rack 9 and the bottom wall inside the case 2. That is, the sample rack 9 extends toward the bottom with a gap therebetween, making full use of the space.

In one embodiment, the present refrigerator may further include a dehumidifying structure 32; the dehumidifying structure 32 may include: a closed box 33, a window frame 34 embedded in the access port 1, and a condenser 35 installed in the closed box 33; the side wall of the access port 1 is provided with an accommodating cavity for accommodating the closed box 33; the closed box 33 is respectively provided with an air inlet and an air outlet; a first fan 36 is installed at the air outlet; the outlet of the first fan 36 is arranged towards the window frame 34; the edge of the window frame 34 at the end away from the sample holder assembly 4 extends outwards and forms a mounting flange 41, and handles 40 are connected to the two sides of the mounting flange 41; a first channel 38 and a second channel 39 are respectively arranged in the window frame 34; one end of the first channel 38 and one end of the second channel 39 both open into the opening of the window frame 34, and the other end of the first channel 38 and the other end of the second channel 39 are respectively in butt joint with the air inlet and the air outlet; air valves 42 are arranged in the first channel 38 and the second channel 39; the sealing door 3 is used to cover the opening of the window frame 34.

After entering the opening of the window frame 34, the outside air is blown into the first channel 38 by the first fan 36, then enters the closed box 33 to exchange heat with the condenser 35 for condensation and drying, and the dried air is sucked by the first fan 36 and blown into the opening of the window frame 34, so that the drying is performed in a reciprocating cycle to achieve the aim of dehumidification; the first heating plate 37 may be provided at an air outlet of the first fan 36, and heated air is blown into the opening of the window frame 34 by the first fan 36, so that the temperature in the opening of the window frame 34 is always maintained at about 20 ℃.

A second fan 43 may be further installed in the first passage 38, and a second heating plate 44 may be installed at an air outlet of the second fan 43, so that when the sample cartridge is not accessed, the second fan 43 blows air heated by the second heating plate 44 into the closed box 33 to remove frost condensed on the condenser 35.

The mounting flange 41 may be provided with a connecting unthreaded hole, the window frame 34 and the like may be connected to the box body 2 by screwing, and when detaching, the screw may be loosened, and the entire window frame 34 may be pulled out by holding the handle 40 with both hands and pulling the window frame 34 outward.

The invention is not limited to the above alternative embodiments, and any other various forms of products can be obtained by anyone in the light of the present invention, but any changes in shape or structure thereof, which fall within the scope of the present invention as defined in the claims, fall within the scope of the present invention.