阅读说明：本技术 包含氧化铋胶体的局部用光子屏障 (Topical photon barriers comprising bismuth oxide colloids ) 是由 昂·阿塔兰 让-诺埃尔·托雷尔 于 2019-10-01 设计创作，主要内容包括：本发明涉及一种局部用组合物,其产生从紫外线辐射到可见光辐射的光子屏障,所述局部用组合物包含掺杂有金属的晶体形式的氧化铋胶体Bi-2O-3。(The present invention relates to a topical composition that produces a photon barrier from ultraviolet radiation to visible radiation, said topical composition comprising bismuth oxide colloid Bi in the form of crystals doped with a metal 2 O 3 。)

1. A topical composition for producing a photon barrier in the range from ultraviolet to visible radiation, said composition comprising bismuth oxide colloid Bi in crystalline form₂O₃The bismuth oxide colloid is characterized in that the bismuth oxide colloid is doped with metal.

2. The composition of claim 1, wherein the bismuth oxide colloid is monoclinic.

3. The composition of claim 1 or 2, wherein the bismuth oxide colloid is of the alpha-phase monoclinic type, i.e. alpha-Bi₂O₃。

4. Composition according to any one of claims 1 to 3, characterized in that the bismuth oxide colloid is only in the alpha-phase monoclinic form, i.e. alpha-Bi₂O₃Exist in the form of (1).

5. Composition according to any one of claims 1 to 4, characterized in that the monoclinic form corresponds to the following lattice parameters:β -112.97 °; at P2_1/cZ is 4 in space group.

6. The composition according to any one of claims 1 to 5, wherein the metal is iron.

7. The composition according to any one of claims 1 to 6, wherein the bismuth oxide colloid is grafted with a biocompatible polymer.

8. The composition according to any one of claims 1 to 7, characterized in that the bismuth oxide colloid is grafted with a biocompatible polymer selected from the group comprising: polyvinylpyrrolidone (PVP) and its copolymers such as triacontyl-PVP, PVP-eicosene or PVP-vinyl acetate, polyvinyl alcohol, polyvinyl chloride, styrenes, polyamides, acrylates, polyesters, polybutenes, polysaccharides such as pullulan, arabinoxylan, cellulose, chitin, chitosan, xanthan gum, dextran, welan gum, gellan gum, gum arabic, hyaluronic acid, cellulose and its derivatives, starch, diutan gum, proteins and their components such as sericin and amino acids, fatty acids, phospholipids, phosphoglycerides, triglycerides, silane coupling agents and mixtures thereof.

9. Composition according to any one of claims 1 to 8, characterized in that it comprises doped bismuth oxide colloids, advantageously grafted with a biocompatible polymer, in a quantity of 1 to 60% by mass, advantageously 20 to 50% by mass, relative to the mass of the composition.

10. Composition according to any one of claims 1 to 9, characterized in that said doped Bi₂O₃The colloid comprises 60 to 100% of a doped bismuth oxide colloid of alpha crystalline form, which is advantageously grafted with a biocompatible polymer.

11. Composition according to any one of claims 1 to 10, characterized in that the doped bismuth oxide colloids, advantageously grafted with biocompatible polymers, have a size of 0.5 to 1000nm, advantageously 0.5 to 100 nm.

12. The composition according to any one of claims 1 to 11, further comprising,

-at least one lipophilic and/or hydrophilic mineral sunscreen selected from the group comprising: titanium oxide (TiO)₂) Zinc oxide (ZnO), iron oxide (Fe)₂O₃) Zirconium oxide (ZrO)₂) Silicon oxide (SiO)₂) Manganese oxide (e.g., MnO), aluminum oxide (Al)₂O₃) Cerium oxide (Ce)₂O₃) And mixtures thereof; and/or

-at least one lipophilic and/or hydrophilic organic sunscreen selected from the group comprising the following INCI names: camphorbenzammonium methylsulfate, homosalate, butyl methoxydibenzoylmethane, phenylbenzimidazole-sulfonic acid, terephthalylenedicamphor-sulfonic acid, butyl methoxydibenzoylmethane, benzylidenecamphor-sulfonic acid, octocrylene, polyacrylamide methyl benzylidenecamphor, ethylhexyl methoxycinnamate, PEG-25PABA, isoamyl p-methoxycinnamate, ethylhexyl triazone, cresotrimazole trisiloxane, diethylhexylbutamido triazone, 4-methylbenzylidene camphor, 3-benzylidenecamphor, ethylhexyl salicylate, ethylhexyldimethyl PABA or octyldimethyl PABA, benzophenone-4/benzophenone-5, methylenebis-benzotriazolyl tetramethylbutylphenol, phenylbisbenzimidazole tetrasulfonate, disodium bis-ethylhexyloxyphenol methoxyphenyl triazine, dihydroxylylbenzidine, Polysiloxane-15, diethylaminohydroxybenzoylbenzoic acid hexyl ester and mixtures thereof.

13. Composition according to any one of claims 1 to 12, characterized in that it further comprises at least one additive chosen from dispersants, wetting agents, stabilizers and pH regulators.

14. Composition according to any one of the preceding claims, characterized in that it is a sunscreen composition.

15. Composition according to any one of the preceding claims, characterized in that it comprises, with respect to the mass of the composition:

1% to 60% of a doped bismuth oxide colloid which is present in the form of an alpha-phase monoclinic system, i.e. alpha-Bi₂O₃And advantageously grafted with a biocompatible polymer;

-2% to 20% of a biocompatible polymer, preferably polyvinylpyrrolidone;

-5% to 25% of a humectant, preferably glycerin;

-0.5% to 5% of a stabilizer, preferably sorbitan monolaurate;

-0.1% to 1% of a pH adjusting agent, preferably citric acid; and

-20% to 80% water and/or oil.

16. Doped Bi₂O₃Use of bismuth oxide colloids, advantageously grafted with a biocompatible polymer, as uv filters, advantageously for the wavelength spectrum from 200 to 420 nm.