阅读说明：本技术 用于局部使用的消毒组合物 (Disinfecting compositions for topical use ) 是由 玛丽-弗朗索瓦丝·希拉克 C·布考特 于 2019-10-09 设计创作，主要内容包括：本发明涉及一种用于局部使用的消毒组合物(C-D),其包含基于椰油酰谷氨酸盐和烷基聚糖苷的表面活性剂混合物(M-1)、至少一种增稠剂和/或胶凝剂、以及至少一种消毒剂。(The invention relates to a disinfecting composition (C) for topical use D ) Comprising a surfactant mixture (M) based on cocoyl glutamate and an alkyl polyglycoside 1 ) At least one thickening and/or gelling agent, and at least one disinfectant.)

1. A disinfecting composition for topical use (C)_D) Said disinfecting composition comprising per 100% of its mass

a) -from 35 to 99.3% by mass of water;

b) -from 0.5 to 40% by mass of at least one disinfectant;

c) -from 0.1 to 10% by mass of at least one gelling and/or thickening Agent (AG);

d) -from 0.1 to 15% by mass of a mixture (M)₁) Said mixture comprising, per 100% of its own mass:

(i) from 50 to 99% by mass of a composition (C)₁) Said composition comprising, per 100% of its mass:

(α) -from 65 to 90% by mass of at least one compound of formula (I):

R₁-C(＝O)-NH-CH(COOH)-(CH₂)₂-COOH (I)

in acid, partially salified or fully salified form, where the radical R₁-C (═ O) -represents a linear or branched, saturated or unsaturated acyl group containing from 8 to 18 carbon atoms, and

(β) -from 10 to 35% by mass of at least one compound of formula (II):

R₁-C(＝O)-OH (II)

in acid, partially salified or fully salified form, where the radical R₁As defined for formula (I),

(ii) from 1 to 50% by mass of a composition (C)₂) Said composition comprising, per 100% of its mass:

(γ) -from 14 to 80% by mass of composition (C)₃) Or composition (C)₃) The composition (C)₃) Represented by formula (III):

R₃-O-(G₃)_p-H (III)

wherein R is₃Denotes a linear or branched, saturated or unsaturated aliphatic radical containing from 12 to 16 carbon atoms, G₃Represents a residue of a reducing sugar, and p represents a decimal number of 1.05 or more and 5 or less;

(delta) -from 20 to 80% of composition (C)₄) Or composition (C)₄) The composition (C)₄) Represented by formula (V):

R₄-O-(G₄)_q-H (V)

wherein R is₄Represents a linear aliphatic radical selected from n-butyl (n-C)₄H₉-, n-pentyl (n-C)₅H₁₁-) n-hexyl (n-C)₆H₁₃-) and n-heptyl (n-C)₇H₁₅-) group, G₄Represents a reducing sugar residue, and q represents a decimal of 1.05 or more and 5 or less.

2. The sanitizing composition (C) as claimed in claim 1_D) Characterized in that the gelling agent and/or thickener (AG) is selected from the group consisting of polysaccharides consisting of derivatives of monosaccharides, polysaccharides consisting of monosaccharides only, cellulose and cellulose derivatives, starch and linear or branched or cross-linked polyelectrolytes.

3. Disinfecting composition (C) according to one of claims 1 and 2_D) Characterized in that said composition (C)₃) Represented by the formula (III)₁)、(III₂)、(III₃)、(III₄) And (III)₅) The composition of the mixture of compounds represented:

R₃-O-(G₃)₁-H (III₁)，

R₃-O-(G₃)₂-H (III₂)，

R₃-O-(G₃)₃-H (III₃)，

R₃-O-(G₃)₄-H (III₄)，

R₃-O-(G₃)₅-H (III₅)，

the compounds being in the respective molar ratios a₁、a₂、a₃、a₄And a₅So that:

sum a₁+a₂+a₃+a₄+a₅Is equal to 1, and

sum a₁+2a₂+3a₃+4a₄+5a₅Is equal to p.

4. Disinfecting composition (C) according to any one of claims 1 to 3_D) Characterized in that said composition (C)₄) Is represented by the formula (V)₁)、(V₂)、(V₃)、(V₄) And (V)₅) The composition of the mixture of compounds represented:

R₄-O-(G₄)₁-H (V₁)，

R₄-O-(G₄)₂-H (V₂)，

R₄-O-(G₄)₃-H (V₃)，

R₄-O-(G₄)₄-H (V₄)，

R₄-O-(G₄)₅-H (V₅)，

the compounds being in respective molar proportions a'₁、a’₂、a’₃、a’₄And a'₅So that:

a's'₁+a’₂+a’₃+a’₄+a’₅Is equal to 1, and

a's'₁+2a’₂+3a’₃+4a’₄+5a’₅Is equal to q.

5. Disinfecting composition (C) according to any of claims 1 to 4_D) Characterized in that said composition (C)₂) Comprises the following steps:

-from 0 to 3% by mass of at least one alcohol of formula (IV):

R₃-OH (IV)

wherein R is₃Is as defined in formula (III), and/or

-from 0 to 3% by mass of at least one alcohol of formula (VI):

R₄-OH (VI)

wherein R is₄Is as defined for formula (V).

6. Disinfecting composition (C) according to any of claims 1 to 5_D) Characterised in that, in the formulae (I) and (II), the radical R₁-C (═ O) -represents an acyl group selected from: octanoyl, decanoyl, dodecanoyl, tetradecanoyl, hexadecanoyl, octadecanoyl, 9-octadecenoyl, 9, 12-octadecadienoyl and 9,12, 15-octadecatrienoyl.

7. Disinfecting composition (C) according to one of claims 1 to 6_D) Characterized in that said composition (C)₂) Per 100% of its mass:

(γ) -14% or more and less than 70% by mass of the composition (C)₃) And are and

(delta) -an alcohol of the formula (IV) in a mass proportion of 0% or more and 3% or less,

(ε) -30-80% by mass or more of the composition (C)₄) And are and

(η) alcohol of formula (VI) in a mass proportion of 0% or more and 3% or less.

8. Disinfecting composition (C) according to any of claims 1 to 7_D) Characterised in that, in the formulae (III) and (IV), R₃Represents a compound selected from n-dodecyl (n-C)₁₂H₂₅-) n-tetradecyl (n-C)₁₄H₂₉-) and n-hexadecyl (n-C)₁₆H₃₂-) straight chain alkyl groups.

9. Disinfecting composition (C) according to any of claims 1 to 8_D) Characterized in that, in the formulae (V) and (VI), R₄Represents a group selected from n-hexyl (n-C)₆H₁₃) And n-heptyl (n-C)₇H₁₅) Linear alkyl groups of the group.

10. Disinfecting composition (C) according to one of claims 1 to 9_D) Characterized in that said composition (C)₂) Comprising a composition (C)₃) And composition (C)₄) The mixture of (a), said mixture comprising per 100% of its mass:

(γ₁) -from 13.6 to 44.4% by mass of a composition (C) represented by formula (III)₃) Wherein R is₃Represents (n-C)₁₂H₂₅) The radical(s) is (are),

(γ₂) -from 5 to 16.25% by mass of a composition (C) represented by formula (III)₃) Wherein R is₃Represents n-tetradecyl (n-C)₁₄H₂₉) A group, and

(γ₃) -from 1.4% to 4.55% by mass of a composition (C) represented by formula (III)₃) Wherein R is₃Represents n-hexadecyl (n-C)₁₆H₃₂) The radical(s) is (are),

(ε₁) -from 35 to 80% by mass of a composition (C) represented by formula (V)₄) Wherein R is₄Represents an n-heptyl group (n-C)₇H₁₅) A group.

11. Disinfecting composition (C) according to one of claims 1 to 10_D) The method is characterized by comprising the following steps of:

(ii) mass/[ composition (C) of one or more compounds of formula (I)₃) Mass + composition (C) of₄) Mass of]And 20/80 or more and 65/35 or less.

12. Disinfecting composition (C) according to one of claims 1 to 11_D) The method is characterized by comprising the following steps of:

Δ₁(II) composition (C)₃) Mass/composition (C)₄) Is greater than or equal to 20/80 and less than or equal to 70/30.

13. Disinfecting composition (C) according to one of claims 1 to 12_D) Characterized in that at least one gelling and/or thickening Agent (AG) is chosen from xanthan gum (G)_X) Gum arabic exudate (G)_A) The xanthan gum (G) is greater than or equal to 1/3 and less than or equal to 3/1_X) With said gum arabic exudate (G)_A) Xanthan gum (G) in mass ratio of_X) And gum arabic exudate (G)_A) A mixture of (a).

14. Disinfecting composition (C) according to one of claims 1 to 13_D) Characterized in that at least the disinfectant is selected from the elements of the group consisting of: sorbic acid, sodium sorbate, potassium sorbate, dehydroacetic acid, sodium dehydroacetate, benzoic acid, sodium benzoate, potassium benzoate; 1- (2-ethylhexyl) glycerol; hydrogen peroxide; activated peroxides, such as mixtures of hydrogen peroxide and sodium bicarbonate, hydrogen peroxide and urea, hydrogen peroxide and peracetic acid, and hydrogen peroxide and iron (fenton's reagent); a hydroperoxycarbonate; peracetic acid; sodium hypochlorite.

15. Disinfecting composition (C) according to one of claims 1 to 14_D) Characterized in that said disinfecting composition comprises, per 100% of its mass:

a) -from 35% to 99.3% water;

b) -from 0.5 to 40% by mass of at least one disinfectant selected from the group consisting of hydrogen peroxide, sodium hypochlorite, potassium sorbate, sodium benzoate, 1- (2-ethylhexyl) glycerol,

c) -from 0.1 to 10% by mass of at least one gelling and/or thickening Agent (AG) selected from the elements of the group consisting of: xanthan Gum (GX), gum arabic exudate (GA), a mixture of xanthan Gum (GX) and gum arabic exudate (GA) in a mass ratio between said xanthan Gum (GX) and said gum arabic exudate (GA) greater than or equal to 1/3 and less than or equal to 3/1;

d) -from 0.1 to 15% by mass of said mixture (M)₁) Wherein:

-the compound of formula (I) is selected from monosodium N-cocoyl glutamate, monopotassium N-cocoyl glutamate, disodium N-cocoyl glutamate and dipotassium N-cocoyl glutamate,

-the compound of formula (II) is selected from sodium cocoate and potassium cocoate,

in formula (III), R₃Denotes a linear or branched, saturated or unsaturated aliphatic radical containing from 12 to 16 carbon atoms, G₃Represents a glucose or xylose residue, and p represents a decimal number of 1.05 or more and 2.5 or less;

in formula (IV), R₃Represents a linear or branched, saturated or unsaturated aliphatic group comprising from 12 to 16 carbon atoms,

in formula (V), R₄Represents an n-heptyl group (n-C)₇H₁₅) Group, G₄Represents a glucose or xylose residue, and q represents a decimal number of 1.05 or more and 2 or less,

in formula (VI), R₄Represents an n-heptyl group (n-C)₇H₁₅) A group.

16. Disinfecting composition (C) according to one of claims 1 to 15_D) It is used for disinfecting and washing hands.

17. Disinfecting composition (C) according to one of claims 1 to 15_D) For treating skin infections, skin burns, scars, wounds in humans or animals.