阅读说明：本技术 医疗设备和信号采集器 (Medical equipment and signal collector ) 是由 马宝宝 吕晓 熊贤志 于 2021-06-30 设计创作，主要内容包括：本申请实施例公开了医疗设备和信号采集器,医疗设备包括：包括处理器、固定部件和K个信号采集器；其中：所述固定部件,能够用于将所述处理器物理连接于目标对象；所述处理器,用于将参考电压通过电压输出端输出给与之电性连接的所述信号采集器；其中,每组信号采集器具有至少一根第一导线,所述第一导线的末端设置有第一连接件；所述第一连接件,用于实现所连接的信号采集器与所述处理器的电压输出端的电性连接和脱离；每组的信号采集器的数目小于K；所述信号采集器,用于与所述处理器电性连接的情况下,采集所述目标对象的第一电压,以及根据所述参考电压和所述第一电压,生成所述目标对象的第一生理信号。(The embodiment of the application discloses medical equipment and signal collector, medical equipment includes: the device comprises a processor, a fixed part and K signal collectors; wherein: the fixed component can be used for physically connecting the processor to a target object; the processor is used for outputting the reference voltage to the signal collector which is electrically connected with the processor through a voltage output end; each group of signal collectors is provided with at least one first wire, and the tail end of each first wire is provided with a first connecting piece; the first connecting piece is used for realizing the electrical connection and disconnection between the connected signal collector and the voltage output end of the processor; the number of the signal collectors in each group is less than K; the signal collector is used for collecting a first voltage of the target object under the condition that the signal collector is electrically connected with the processor, and generating a first physiological signal of the target object according to the reference voltage and the first voltage.)

1. The medical equipment is characterized by comprising a processor, a fixed part and K signal collectors; wherein:

the fixed component can be used for physically connecting the processor to a target object;

the processor is used for outputting the reference voltage to the signal collector which is electrically connected with the processor through a voltage output end; each group of signal collectors is provided with at least one first wire, and the tail end of each first wire is provided with a first connecting piece; the first connecting piece is used for realizing the electrical connection and disconnection between the connected signal collector and the voltage output end of the processor; the number of the signal collectors in each group is less than K;

the signal collector is used for collecting a first voltage of the target object under the condition that the signal collector is electrically connected with the processor, and generating a first physiological signal of the target object according to the reference voltage and the first voltage.

2. The medical device of claim 1, wherein the number of signal collectors in each group is 1, each signal collector has a first lead, and the first leads are flexible.

3. The medical device of claim 1 or 2, further comprising a hub member and a support member; wherein the content of the first and second substances,

the supporting component is conductive, the first end of the supporting component is used for realizing the electrical connection with the voltage output end of the processor, and the second end of the supporting component is used for realizing the electrical connection with the voltage input end of the pivot component;

the pivot part is provided with second connecting pieces which are arranged at different positions and matched with the first connecting pieces, and the second connecting pieces are electrically connected with the voltage input end and used for realizing the electrical connection between the signal collector and the voltage output end of the processor through the contact connection of the first connecting pieces at the tail ends of the first wires of the signal collector.

4. The medical device of claim 3, wherein the first connector is a snap-fit component and the second connector is an assembly component that snaps-fits with the snap-fit component;

the second connecting piece is used for supporting the connection and the disconnection of the first connecting piece, so that the connection and the disconnection of the signal collector and the processor are realized.

5. The medical device of claim 3, wherein the first end of the support member is provided with a first magnetic member and the voltage output of the processor is provided with a second magnetic member;

the first magnetic piece and the second magnetic piece are mutually adsorbed, so that the first end of the supporting component is electrically connected with the voltage output end of the processor;

the second end of the supporting component is provided with a third magnetic force piece, and the voltage input end of the pivot component is provided with a fourth magnetic force piece;

the third magnetic piece and the fourth magnetic piece are mutually adsorbed, so that the second end of the supporting component is electrically connected with the voltage input end of the pivot component.

6. The medical device according to claim 1 or 2, wherein the signal collector comprises a first wireless communication means for transmitting the first physiological signal to a terminal device through a wireless connection channel with the terminal device.

7. The medical device according to claim 1 or 2, wherein a surface of the signal collector is provided with a conductive gel for adhering to the skin of the target object so as to collect the first voltage of the target object.

8. The medical apparatus according to claim 1 or 2, further comprising at least one electrode and a second wireless communication device; wherein the content of the first and second substances,

the electrode is electrically connected with the processor through a second lead and is used for collecting a second voltage of the target object;

the processor is further configured to generate a second physiological signal of the target object according to the second voltage;

and the second wireless communication device is used for transmitting the second physiological signal to the terminal equipment through a wireless connection channel with the terminal equipment.

9. The medical device of claim 8, wherein the at least one electrode comprises a first electrode and a second electrode; wherein the first electrode is used for acquiring voltage at a first position of the target object, and the second electrode is used for acquiring voltage at a second position of the target object;

the fixing part is in a strip shape, and a third electrode is arranged on the fixing part; wherein the third electrode is for acquiring a voltage at a third location of the target object;

the processor is configured to output the mean voltage of the first electrode, the second electrode, and the third electrode as the reference voltage to the signal collector through the voltage output terminal, so that the signal collector generates the first physiological signal according to a voltage difference between the reference voltage and the first voltage; wherein the first physiological signal is an electrocardiosignal.

10. A signal collector is characterized by comprising a first wire, wherein the tail end of the first wire is provided with a first connecting piece;

the first connecting piece is used for realizing the electrical connection and disconnection between the signal collector and the voltage output end of the processor of the medical equipment;

the signal collector is used for collecting a first voltage of a target object where the processor is located under the condition that the signal collector is electrically connected with the processor, and generating a first physiological signal according to the reference voltage and the first voltage.

Technical Field

The embodiment of the application relates to electronic technology, and relates to but is not limited to medical equipment and a signal collector.

Background

With the advent of aging society, various cardiovascular diseases are highly developed as elderly people, and become an important medical burden for families of patients and the whole society. Because cardiovascular diseases are long-term, cumulative, and occasionally discovered, conventional periodic testing is not effective in preventing such diseases, and it is currently common practice to use a portable dynamic electrocardiograph (Holter) for long-term testing of heart health. However, the comfort of wearing by the patient of the current dynamic electrocardiograph is still to be improved.

Disclosure of Invention

The medical equipment that this application embodiment provided includes: the device comprises a processor, a fixed part and K signal collectors; wherein: the fixed component can be used for physically connecting the processor to a target object; the processor is used for outputting the reference voltage to the signal collector which is electrically connected with the processor through a voltage output end; each group of signal collectors is provided with at least one first wire, and the tail end of each first wire is provided with a first connecting piece; the first connecting piece is used for realizing the electrical connection and disconnection between the connected signal collector and the voltage output end of the processor; the number of the signal collectors in each group is less than K; the signal collector is used for collecting a first voltage of the target object under the condition that the signal collector is electrically connected with the processor, and generating a first physiological signal of the target object according to the reference voltage and the first voltage.

The signal collector provided by the embodiment of the application is provided with a first wire, wherein a first connecting piece is arranged at the tail end of the first wire; the first connecting piece is used for realizing the electrical connection and disconnection between the signal collector and the voltage output end of the processor of the medical equipment; the signal collector is used for collecting a first voltage of a target object where the processor is located under the condition that the signal collector is electrically connected with the processor, and generating a first physiological signal according to the reference voltage and the first voltage.

The embodiment of the application provides medical equipment and a signal collector, wherein the medical equipment is provided with K signal collectors which are divided into at least two groups of signal collectors, each group of signal collectors has a collecting function of a first physiological signal and supports the electrical connection and the disconnection with a voltage output end of a processor; therefore, the flexibility is stronger, and the user can flexibly select the signal collector worn by the target object according to the requirement, so that the wearing comfort of the target object is improved.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and, together with the description, serve to explain the principles of the application.

FIG. 1 is a schematic structural diagram of a medical device according to an embodiment of the present application;

FIG. 2 is another schematic structural view of a medical device according to an embodiment of the present application;

FIG. 3 is a schematic view of another embodiment of a medical device according to the present application;

fig. 4 is a schematic structural diagram of a signal collector in the embodiment of the present application;

fig. 5 is another schematic structural diagram of a signal collector according to an embodiment of the present application;

FIG. 6 is a schematic structural diagram of an electrocardiograph detection device 6 according to an embodiment of the present application;

FIG. 7 is a schematic diagram of a signal collector according to an embodiment of the present application;

FIG. 8 is a schematic view of the entire wearing of the electrocardiograph detection device according to the embodiment of the present application;

fig. 9 is a schematic view of a work flow of the electrocardiograph detection device according to the embodiment of the present application.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, specific technical solutions of the present application will be described in further detail below with reference to the accompanying drawings in the embodiments of the present application. The following examples are intended to illustrate the present application but are not intended to limit the scope of the present application.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing embodiments of the present application only and is not intended to be limiting of the application.

In the following description, reference is made to "some embodiments" which describe a subset of all possible embodiments, but it is understood that "some embodiments" may be the same subset or different subsets of all possible embodiments, and may be combined with each other without conflict.

It should be noted that reference to the terms "first \ second \ third" in the embodiments of the present application does not denote a particular ordering with respect to the objects, and it should be understood that "first \ second \ third" may be interchanged under certain circumstances or of a certain order, such that the embodiments of the present application described herein may be performed in an order other than that shown or described herein.

An embodiment of the present application provides a medical device, fig. 1 is a schematic structural diagram of the medical device according to the embodiment of the present application, and as shown in fig. 1, the medical device 1 includes a processor 11, a fixing component 12, and K signal collectors 13; wherein:

a fixed component 12 that can be used to physically connect the processor 11 to a target object;

the processor 11 is used for outputting the reference voltage to the signal collector 13 which is electrically connected with the reference voltage through a voltage output end; each group of signal collectors 13 has at least one first wire 131, and a first connecting member 132 is disposed at a terminal of the first wire 131; the first connecting piece 132 is used for realizing the electrical connection and disconnection between the connected signal collector 13 and the voltage output end of the processor 11; the number of signal acquisition of each group is less than K;

the signal collector 13 is configured to collect a first voltage of the target object under the condition that the signal collector is electrically connected to the processor 11, and generate a first physiological signal of the target object according to the reference voltage and the first voltage.

In an embodiment of the present application, a medical device is provided, which includes K signal collectors, and is divided into at least two groups of signal collectors, where each group of signal collectors has a function of collecting a first physiological signal and supports electrical connection and disconnection with a voltage output terminal of a processor; therefore, the flexibility is stronger, and the user can flexibly select the signal collector worn by the target object according to the requirement, so that the wearing comfort of the target object is improved. For example, the medical device is an electrocardiograph detection device, and doctors commonly use a V2 lead and a V5 lead, if one group of signal collectors includes a signal collector for collecting V2 and a signal collector for collecting V5, or if one group of signal collectors includes a signal collector for collecting V2 and the other group of signal collectors includes a signal collector for collecting V5, the doctors only need to select one or two groups of signal collectors, and do not need to wear other redundant signal collectors on the patient, thereby effectively improving the wearing comfort of the patient.

It should be noted that the target object may be any type of organism, for example, the target object is a human body, and for example, the target object is an animal body.

The number of signal collectors 13 in each group may be the same or different. The user can flexibly select one or more groups of signal collectors 13 according to the number of actually required signal collectors. For example, if the user needs 2 signal collectors at this time, a group of 2 signal collectors 13 may be selected; as another example, if the user needs 4 signal collectors at this time, a group of 4 signal collectors 13 may be selected.

The number of signal collectors 13 in a group may be any number. The number of signal collectors 13 in each group may be the same as or different from the number of first wires 131. Meanwhile, each signal collector 13 is correspondingly connected with a first wire 131; at different times, i.e. the number of signal collectors 13 in a group is greater than the number of first wires 131, at least two signal collectors 13 share one first wire 131.

In some embodiments, the number of each group of signal collectors 13 is 1, each signal collector 13 has one first wire 131, and the wire has scalability; therefore, on one hand, each group of signal collectors is provided with one signal collector 13, so that the flexibility is stronger, and the wearing comfort is greatly improved, for example, a doctor only needs the first physiological signal of 1 position point, and then selects one corresponding signal collector 13; if the doctor needs the first physiological signal of 3 position points, the doctor can select 3 signal collectors; on the other hand, the user can control the extending length of the first wire 131 according to the distance length actually required, so that the problem of poor wearing comfort of the user caused by the fact that the first wire 131 is too long and is wound is avoided.

In some embodiments, the signal collector 13 may generate the first physiological signal of the target object according to a voltage difference between the reference voltage and the first voltage.

It should be noted that the first physiological signal may be various types of signals, which is not limited in the embodiment of the present application. For example, the first physiological signal is an electrocardiographic signal.

Fig. 2 is a schematic structural diagram of the medical apparatus according to the embodiment of the present application, and as shown in fig. 2, the medical apparatus 2 includes a processor 11, a fixing component 12, K signal collectors 13, a pivot component 21, a supporting component 22, at least one electrode 23, and a second wireless communication device 24; wherein:

a support member 22 having conductivity, a first end for electrically connecting with a voltage output terminal of the processor 11, and a second end for electrically connecting with a voltage input terminal of the hinge member 21;

the pivot part 21 is provided with second connecting pieces 211 matched with the first connecting pieces 132 at different positions, and the second connecting pieces 211 are electrically connected with the voltage input end and used for realizing the electrical connection between the signal collector 13 and the voltage output end of the processor 11 through the contact connection of the first connecting pieces 132 at the tail ends of the first wires 131 of the signal collector 13. Wherein the first connecting member 132 and the second connecting member 211 are not shown in the figure;

the electrode 23 is electrically connected with the processor 11 through a second lead 25 and is used for acquiring a second voltage of the target object;

the processor 11 is further configured to generate a second physiological signal of the target object according to the second voltage;

the fixing part 12 is further configured to fix a second wireless communication device 24 on the target object, and the second wireless communication device 24 is configured to transmit the second physiological signal to the terminal device through a wireless connection channel with the terminal device.

In the present embodiment, the medical apparatus further includes a hinge member 21 and a support member 22; in this way, compared with the case that the first wire 131 is directly connected to the voltage output end of the processor 11, the extension length of the first wire of the signal collector worn by the target object can be further shortened, so that the problem of poor wearing comfort caused by the overlong wire can be further improved.

It should be noted that the shape of the pivot member 21 can be various, for example, the pivot member is disc-shaped, strip-shaped or arc-shaped; the disk shape may be various shapes, such as a circle, a sector, or a square, among others.

Also, the type of the support member 22 is not limited, and various types of members having a support function are possible. For example, the member is a support member formed of at least one support rod.

In some embodiments, the first end of the supporting member 22 may be electrically connected to the voltage output terminal of the processor 11 by soldering or contact connection. It will be appreciated that welding makes the support member 22 fixed to the disposer 11 and not removable, as opposed to contact connection, which makes the support member 22 removable at any time; in this manner, when any signal collector 13 is not required, the target subject can be free from wearing the support member 22 and the pivot member 21, thereby further improving wearing comfort.

The connection of the corresponding second wire 25 to the processor 11 is not limited, and may be a soldering or contact connection.

In the embodiments of the present application, implementation of the contact connection is not limited. Can be realized by magnetic attraction, plugging, pasting or hooking and the like. The hook connection is, for example, a structure of one connecting member is in a hook shape, and a structure of the other connecting member is in a hole shape.

In some embodiments, the first end of the support member 22 is provided with a first magnetic member, and the voltage output of the processor 11 is provided with a second magnetic member; the first magnetic member and the second magnetic member are attracted to each other, so that the first end of the supporting member 22 is electrically connected to the voltage output end of the processor 11.

In some embodiments, the second end of the supporting member 22 is provided with a third magnetic member, and the voltage input end of the pivot member 21 is provided with a fourth magnetic member; the third magnetic member and the fourth magnetic member are attracted to each other, so that the second end of the supporting member 22 is electrically connected to the voltage input end of the pivotal member 21.

In some embodiments, as shown in fig. 3, the at least one electrode 23 comprises a first electrode 231 and a second electrode 232; wherein, the first electrode 231 is used for collecting the voltage at the first position of the target object, and the second electrode 232 is used for collecting the voltage at the second position of the target object; the fixing member 12 is in a belt shape, and the third electrode 31 is provided on the fixing member 12; wherein the third electrode 31 is used for acquiring a voltage at a third position of the target object; the processor 11 is configured to output the average voltage of the first electrode 231, the second electrode 232, and the third electrode 31 as the reference voltage to the signal collector 13 through the voltage output end, so that the signal collector 13 generates the first physiological signal according to a voltage difference between the reference voltage and the first voltage; wherein the first physiological signal and the second physiological signal are electrocardiosignals.

In some embodiments, the first electrode 231 is an RA electrode for acquiring a voltage at the RA location of the target object; the second electrode 232 is an LA electrode for collecting a voltage at an LA position of the target object; the third electrode 31 is an LL electrode for acquiring a voltage at the LL position of the target object.

In some embodiments, as shown in fig. 3, a fourth electrode 32 is further disposed on the fixed member 12 for collecting a voltage at a fourth location of the target object.

In some embodiments, the fourth electrode 32 is a RL electrode for acquiring a voltage at the RL location of the target object.

In some embodiments, the first connecting member 132 is a clamping member, and the second connecting member 211 is a mounting member clamped with the clamping member; and a second connecting member 211 for supporting the connection and disconnection of the first connecting member 132, thereby realizing the connection and disconnection of the signal collector 13 and the processor 11.

It should be noted that the first connecting element 132 and the second connecting element 211 may be various types of connecting elements, which are not limited in the embodiments of the present application. For example, the first connecting member 132 is a metal pin, and the second connecting member 211 is a metal slot; for another example, the first connecting member 132 is a metal hook, and the second connecting member 211 is a fastening hole.

An embodiment of the present application provides a signal collector, fig. 4 is a schematic structural diagram of the signal collector in the embodiment of the present application, and as shown in fig. 4, a signal collector 13 has a first wire 131, and a first connecting member 132 is disposed at a terminal of the first wire 131;

the first connecting piece 132 is used for realizing the electrical connection and disconnection between the signal collector 13 and the voltage output end of the processor 11 of the medical equipment;

the signal collector 13 is configured to collect a first voltage of a target object where the processor 11 is located under the condition that the signal collector is electrically connected to the processor 11, and generate a first physiological signal according to the reference voltage and the first voltage.

In some embodiments, the signal collectors 13 each have one first wire 131, and the first wires 131 have scalability.

In some embodiments, as shown in fig. 5, the signal collector 13 includes a first wireless communication device 133, and the first wireless communication device 133 is configured to transmit the first physiological signal to the terminal device through a wireless connection channel with the terminal device.

It should be noted that the first wireless communication device 133 and the aforementioned second wireless communication device 24 may be various types of communication devices. For example, bluetooth, RFID, WiFi direct, ZigBee, D2D, or cellular communication device.

In some embodiments, the first wireless communication device 133 and the second wireless communication device 24 can transmit both the physiological signal to be transmitted and the corresponding acquisition timestamp to the terminal device, thereby eliminating transmission delay caused by wireless transmission.

In some embodiments, when the signal collector 13 and the processor 11 buffer the physiological signal to be transmitted, the corresponding collection time stamp may also be buffered together.

In some embodiments, a surface of the signal collector 13 has a conductive gel, which is used to adhere to the skin of the target object, so as to collect the first voltage of the target object.

An exemplary application of the embodiments of the present application in a practical application scenario will be described below.

In the embodiment of the application, a wearable electrocardiogram detection device with 12 leads is provided, which is an example of a medical device with the improved foregoing, and can effectively solve the influence of the lead lines on the daily life of a patient, and is suitable for being worn for a long time to detect the heart, so as to provide more data support for a doctor to accurately diagnose a disease.

As shown in fig. 6, the electrocardiographic detection device 6 includes a host 61, the host 61 contains a TI electrocardiograph chip, and the TI electrocardiograph chip can complete signal acquisition of 4 limb electrodes and output a wilson central terminal voltage value. The host 61 contains a main control chip and can complete bluetooth connection, data transmission and data storage. On the main unit 61, there is a removable magnetic-type connection device 62 (an example of the support member 22), one end of which is connected to the wilson center terminal of the main unit 61 (an example of the aforementioned voltage output terminal of the processor 11), and one end of which is a disc 63 (an example of the aforementioned pivot member 21), and the disc 63 has 6 metal slots 631 (an example of the second connection member 211) and a ground connection point (not shown) for connecting to the extended signal collector.

The strap 64, to which two silver fabric electrodes 641 and 642 are fixed, serves as the RL electrode and the LL electrode. The strap 64 also serves to secure the host 61.

As shown in fig. 7, an example of the signal collector 13 is provided with an ADC chip, a main control chip and a bluetooth chip. The bottom of the device is adhered with conductive gel, which can be directly adhered to the skin to collect chest signals (an example of a first physiological signal), the tail of the device is provided with an automatically retractable lead (an example of a first lead 131), and the tail end of the lead is provided with a metal needle (an example of a first connecting piece 132). When the signal collector is used for collecting chest lead signals, the metal needle is inserted into a metal clamping groove on the disc shown in fig. 6.

Fig. 8 is a schematic view of the entire wearing of the electrocardiograph detection device, as shown in fig. 8, two limb electrodes (i.e., RA electrode and LA electrode) of the upper limb are connected by wire, and two limb electrodes (i.e., RL electrode and LL electrode) of the lower limb utilize fabric electrodes on the binding band. Depending on the condition, two lead lines (an example of the first lead 131) may suffice if only 6 lead signals (i.e., I/II/III/aVR/aVL/aVF) need to be acquired.

According to the disease condition, if chest lead detection signals such as V2 and V5 leads commonly used by doctors need to be added, only a magnetic disc and two signal collectors need to be added, the two signal collectors are respectively attached to the position points of the chest leads V2 and V5, and a telescopic wire is connected to a metal clamping groove of the disc.

And so on, when the standard 12-lead signal needs to be acquired, 6 signal acquisition devices are added.

Therefore, the 3 lead wires can meet the standard 12-lead electrocardiosignal acquisition, the wearing comfort of the patient can be greatly improved, the wearable electrocardiosignal acquisition device is suitable for long-term wearing, and more reference data are provided for the diagnosis of doctors.

In the embodiment of the application, the whole machine system comprises basic part equipment (a host, a binding band and a magnetic type connecting device) and 6 wireless signal collectors, and the whole machine can realize the functions of different leads according to the number of the selected signal collectors. For example, a basic version of 4 limb electrode (RA/LA/LL/RL) signals is used, the complete machine can realize 6-lead waveform signals, on the basis, a signal collector can be added at will to collect a certain chest lead signal, and when all 6 chest lead signals are collected, the complete machine is 12-lead electrocardiogram detection equipment.

The whole wearing is as shown in fig. 8, after wearing, the whole machine starts to work, and the work flow is as shown in fig. 9, and the method comprises the following steps 901 to 906:

step 901, starting up;

step 902, the host computer and the signal collector of the basic part establish Bluetooth connection with the terminal equipment;

step 903, collecting 4 limb electrode signals by a host of the basic part, performing system processing to generate 6-lead electrocardiogram data, and storing the data; when data are stored, the initial data are timestamp data, the electrocardiogram data are stored subsequently, and the acquisition time point of each data can be calculated;

step 904, the host of the base part outputs the voltage of the 3 collected limb electrodes (i.e. LA/RA/LL) to the magnetic-type connecting device through a Wilson Central Terminal (WCT), so as to output the voltage to the metal card slot;

step 905, a signal collector collects body surface voltage Vp through a bottom conductive gel electrode, the body surface voltage Vp is connected with a metal clamping groove through a telescopic lead, voltage output by the WCT is obtained and is used as Vn, Vp and Vn are calculated through an ADC in a differential input mode, and lead data corresponding to a chest lead are generated and stored; when data are stored, the initial data are timestamp data, the electrocardiogram data are stored subsequently, and the acquisition time point of each data can be calculated;

step 906, eliminating data delay caused by Bluetooth connection through the timestamp, ensuring that each data of each lead signal acquired at the same time is at the same time point, rearranging the original database by the algorithm, outputting 12-lead electrocardio original data for processing by the electrocardio annotation software, and outputting the heart disease condition for reference of a doctor.

Different diseases occur at different heart positions and can be reflected on corresponding lead waveforms, and the electrocardio detection equipment enables doctors or patients to flexibly select the number of leads. For different diseases, doctors or patients can select proper lead numbers, namely proper signal collector numbers, according to needs, so that the wearing comfort of the patients can be greatly improved.

It should be appreciated that reference throughout this specification to "one embodiment" or "an embodiment" or "some embodiments" or "other embodiments" means that a particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment of the present application. Thus, the appearances of the phrases "in one embodiment" or "in an embodiment" or "in some embodiments" or "in other embodiments" in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments. It should be understood that, in the various embodiments of the present application, the sequence numbers of the above-mentioned processes do not mean the execution sequence, and the execution sequence of each process should be determined by its function and inherent logic, and should not constitute any limitation to the implementation process of the embodiments of the present application. The above-mentioned serial numbers of the embodiments of the present application are merely for description and do not represent the merits of the embodiments. The foregoing description of the various embodiments is intended to highlight various differences between the embodiments, and the same or similar parts may be referred to each other, and for brevity, will not be described again herein.

The term "and/or" herein is merely an association relationship describing an associated object, and means that three relationships may exist, for example, object a and/or object B, may mean: the object A exists alone, the object A and the object B exist simultaneously, and the object B exists alone.

It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.

In the several embodiments provided in the present application, it should be understood that the disclosed apparatus and method may be implemented in other ways. The above-described embodiments are merely illustrative, and for example, the division of the modules is only one logical functional division, and other divisions may be realized in practice, such as: multiple modules or components may be combined, or may be integrated into another system, or some features may be omitted, or not implemented. In addition, the coupling, direct coupling or communication connection between the components shown or discussed may be through some interfaces, and the indirect coupling or communication connection between the devices or modules may be electrical, mechanical or other.

The methods disclosed in the several method embodiments provided in the present application may be combined arbitrarily without conflict to obtain new method embodiments.

Features disclosed in several of the product embodiments provided in the present application may be combined in any combination to yield new product embodiments without conflict.

The features disclosed in the several method or apparatus embodiments provided in the present application may be combined arbitrarily, without conflict, to arrive at new method embodiments or apparatus embodiments.

The above description is only for the embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily conceive of changes or substitutions within the technical scope of the present application, and shall be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.