阅读说明：本技术 一种双层密封式冻存瓶 (Double-layer sealed cryopreservation bottle ) 是由 寇剑斌 郑慧云 于 2021-03-04 设计创作，主要内容包括：本发明公开了一种双层密封式冻存瓶,涉及冻存瓶技术领域,包括该冻存瓶主要组成结构件包含：瓶身、下瓶塞、上瓶塞、瓶盖、保护盖。本发明中冻存瓶瓶身和瓶盖拧紧后由瓶颈和瓶盖的锯齿型结构起到防松作用,瓶身和瓶盖之间用下瓶塞进行头层密封,瓶内注射药物后再由上瓶塞与保护盖进行再次密封,保证了密封的完整性,第一层密封结构带螺纹防松结构,适用于人工装配；第二层密封结构是卡扣结构,适用于机器压制装配,本发明的密封方式较激光密封方式避免了激光密封时逸出的光线进入瓶内,对药物产生不良影响。(The invention discloses a double-layer sealed cryopreservation bottle, relating to the technical field of cryopreservation bottles, comprising the following main components: body, lower bottle plug, go up bottle plug, bottle lid, visor. According to the invention, the anti-loosening effect is achieved by the sawtooth-shaped structures of the bottle neck and the bottle cap after the bottle body and the bottle cap are frozen and stored and screwed down, the bottle body and the bottle cap are sealed in the first layer by the lower bottle plug, and the bottle is sealed again by the upper bottle plug and the protective cover after medicine is injected into the bottle, so that the integrity of sealing is ensured; the second layer of sealing structure is a buckle structure and is suitable for machine pressing and assembling, and compared with a laser sealing mode, the sealing mode of the invention prevents light escaping during laser sealing from entering the bottle and generating adverse effects on medicines.)

1. The utility model provides a double-deck sealed cryopreserved bottle, includes cryopreserved bottle body (1), its characterized in that: the freezing bottle body (1) open-top inboard matching of depositing is equipped with down bottle plug (2), the freezing bottle body (1) top outside of depositing in bottle plug (2) top is equipped with threaded connection's bottle lid (3) down, bottle lid (3) top outside is equipped with swing joint's visor (5), visor (5) bottom center is equipped with bottle plug (4), bottle plug (2) top center is equipped with first boss down, bottle lid (3) top center be equipped with first boss assorted puncture preformed hole, go up bottle plug (4) bottom center be equipped with puncture preformed hole assorted second boss, visor (5) top one side is equipped with the tear line.

2. The double-deck sealed cryopreservation bottle of claim 1, wherein: the freezing bottle body (1), the bottle cap (3) and the protective cover (5) are all made of a high polymer composite material (COC) resistant to extremely low temperature (-196 ℃ and below).

3. The double-deck sealed cryopreservation bottle of claim 1, wherein: the lower bottle stopper (2) and the upper bottle stopper (4) are respectively made of colorless and extremely low temperature resistant silica gel material (196 ℃ below zero) or thermoplastic rubber (TPE).

4. The double-deck sealed cryopreservation bottle of claim 1, wherein: the bottom of the outer wall of the top opening of the freezing bottle body (1) is provided with first annular helical teeth, and the bottom of the bottle cap (3) is provided with second annular helical teeth matched with the first annular helical teeth.

5. The double-deck sealed cryopreservation bottle of claim 1, wherein: the freezing bottle is characterized in that an external thread is arranged on the outer wall of an opening of the bottle body (1), and an internal thread matched with the external thread is arranged on the inner wall of the bottom of the bottle cap (3).

6. The double-deck sealed cryopreservation bottle of claim 1, wherein: the bottle cap is characterized in that an annular bayonet is arranged at the top of the bottle cap (3), and clamping fingers matched with the annular bayonet are arranged at the bottom of the protective cover (5).

7. The double-deck sealed cryopreservation bottle of claim 1, wherein: and a labyrinth sealing structure is arranged between the bottle cap (3) and the protective cover (5).

8. The double-deck sealed cryopreservation bottle of claim 1, wherein: and a connecting sheet is arranged on one side of the tearing line on the outer wall of the protective cover (5).

9. The double-deck sealed cryopreservation bottle of claim 1, wherein: the sum of the heights of the first boss and the second boss is equal to the depth of the reserved piercing hole.

Technical Field

The invention relates to the technical field of freezing bottles (tubes), in particular to a double-layer sealed freezing bottle.

Background

The sealed frozen bottle is a transparent package for storing vaccine and biological preparation, and its bottle body, bottle cap and protector are made of imported high-molecular composite material (COC), and they are very strong in low-temp. resistance (working temp. normal temp. to-196 deg.C (liquid nitrogen gas phase)), and can be extensively used for storing biological preparation of vaccine, etc..

At present, the sealing mode of the common cryopreservation bottle is to realize the sealing of the cryopreservation bottle by burning and melting the puncture hole by laser (for example, patent US7851538B2), and the main disadvantages of the laser sealing are as follows: in general, a small amount of escaping light enters the bottle through the rubber plug, and unpredictable damage is caused to the preparation.

Disclosure of Invention

The invention aims to provide a double-layer sealed freezing bottle to solve the problems in the background technology.

In order to solve the technical problems, the invention provides the following technical scheme: the utility model provides a double-deck sealed freezes deposits bottle, includes freezes deposits bottle body, it is equipped with down the bottle plug to freeze and deposits bottle body open-top inboard matching, freeze deposit bottle body top outside in the bottle plug top is equipped with threaded connection's bottle lid down, the bottle lid top outside is equipped with swing joint's visor, visor bottom center is equipped with the bottle plug, bottle plug top center is equipped with first boss down, bottle lid top center be equipped with first boss assorted puncture preformed hole, go up bottle plug bottom center be equipped with puncture preformed hole assorted second boss, visor top one side is equipped with the tear line.

Furthermore, the bottle body, the bottle cover and the protective cover of the freezing bottle are all made of polymer composite materials (COC), and the materials can keep the size integrity at extremely low temperature (-196 ℃), so that the low-temperature resistance of the whole structure of the freezing bottle is ensured.

Furthermore, the lower bottle plug and the upper bottle plug are respectively made of special silica gel materials or thermoplastic rubber (TPE), and the materials can keep the size integrity at extremely low temperature (-196 ℃), so that the flexible sealing treatment effect of the sealing structure is ensured.

Further, freezing and depositing bottle body open-top outer wall bottom and be equipped with first annular skewed tooth, the bottle lid bottom be equipped with first annular skewed tooth assorted second annular skewed tooth, freezing and depositing bottle body and bottle lid are held between the arms and are held with the second annular through first annular and link together, form not hard up dead lock structure, guarantee the linkage effect of freezing and depositing bottle body and bottle lid.

Further, the outer wall of the opening of the frozen bottle body is provided with an external thread, the inner wall of the bottom of the bottle cap is provided with an internal thread matched with the external thread, the frozen bottle body is connected with the bottle cap through threads, and therefore a thread bevel effect is formed to compress the helical teeth and prevent the helical teeth from being staggered up and down.

Furthermore, the top of the bottle cap is provided with an annular bayonet, and the bottom of the protective cover is provided with clamping fingers (the number of the clamping fingers is at least more than 3, so as to ensure uniform stress), which are matched with the annular bayonet, so that the bottle cap and the protective cover are connected in a buckling manner.

Furthermore, a labyrinth seal structure is arranged between the inner side of the bottle cap and the protective cover, so that the sealing connection effect among the bottle cap, the upper bottle plug and the protective cover is ensured.

Furthermore, the outer wall of the protective cover is provided with a connecting sheet on one side of the tearing line, and the protective cover can be torn along the tearing line by using a hand through the connecting sheet, so that the operation is more convenient.

Furthermore, the sum of the heights of the first boss and the second boss is equal to the depth of the puncture preformed hole, so that the first boss and the second boss can be simultaneously inserted into the puncture preformed hole, and the bosses play a role in assembly and positioning.

Compared with the prior art, the invention has the following beneficial effects:

1. the invention sets a freezing bottle body, a lower bottle stopper, an upper bottle stopper, a bottle cap and a protective cover, and the sealing mode is as follows: before filling, pressing a lower bottle plug of a sealing element into a bottle mouth of a frozen bottle, screwing a bottle cap, pressing the edge of the lower bottle plug by a thread pair between the bottle cap and a bottle body of the frozen bottle, and locking the bottle cap by an oblique tooth loose-proof structure of the bottle cap and a bottle shoulder to form a first layer of sealing; after puncture filling, an upper bottle stopper of the sealing element is pressed to the upper part of the bottle cap through the protective cover, the seal is used for positioning through a second boss of the upper bottle stopper, and the seal is kept by the labyrinth seal between the protective cover and the bottle cap and the clamping force of the clamping fingers of the protective cover to form a second layer of seal; the tear line of the protective cover tape is convenient for being opened by hands; the double-layer sealed cryopreservation bottle has the advantages that the overall dimension is completely consistent with that of the traditional laser sealed cryopreservation bottle, the filling line efficiency is the same, and the main difference is that the sealing modes of the puncture holes are different.

2. The working mode of the double-layer sealed cryopreservation bottle of the invention is as follows: before filling, the lower bottle stopper, the frozen bottle body and the bottle cap are assembled in advance in a ten thousand-level clean environment (the three parts can form a complete sealing structure); the pre-assembled bottle is placed at a filling station, after the preparation is punctured and filled, the upper bottle stopper of the sealing element is pressed to the upper part of the bottle cap through the protective cover, the sealing is used for positioning through the second boss of the upper bottle stopper, the sealing is kept by the labyrinth seal between the protective cover and the bottle cap and the clamping force of the clamping fingers of the protective cover, a second layer of complete sealing is formed, meanwhile, the tear line of the cover tape is protected, and the bottle cap can be conveniently opened by hands at normal temperature in the later period; the first layer of sealing structure is provided with a thread anti-loosening structure and is suitable for manual assembly; the second layer of sealing structure is a buckle structure and is suitable for machine pressing assembly.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:

FIG. 1 is a front sectional view of the present invention as a whole;

FIG. 2 is a front sectional view of the body of the cryopreservation bottle of the present invention;

FIG. 3 is a top view of FIG. 2 of the present invention;

FIG. 4 is an isometric view of FIG. 2 of the present invention;

fig. 5 is a front elevational view of the lower closure of the present invention;

FIG. 6 is a top view of the invention of FIG. 5;

FIG. 7 is an isometric view of FIG. 5 of the present invention;

fig. 8 is a cross-sectional view of the bottle cap of the present invention;

FIG. 9 is a top view of the invention of FIG. 8;

FIG. 10 is an isometric view of FIG. 8 of the present invention;

fig. 11 is a cross-sectional view of the upper bottle closure of the present invention;

FIG. 12 is a top view of FIG. 11 in accordance with the present invention;

FIG. 13 is a cross-sectional view of a protective cap of the present invention;

FIG. 14 is a top plan view of FIG. 13 in accordance with the present invention;

FIG. 15 is an isometric view of FIG. 13 of the present invention;

in the figure: 1. freezing and storing the bottle body; 2. a bottle stopper is arranged; 3. a bottle cap; 4. a bottle stopper is arranged; 5. a protective cover.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The double-layer sealed freezing bottle as shown in figures 1-15 comprises a freezing bottle body 1, the inner side of the top opening of the freezing bottle body 1 is provided with a lower bottle stopper 2 in a matching way (the surface of the lower bottle stopper 2 can be provided with an annular sealing edge), the outer side of the top of the freezing bottle body 1 is provided with a bottle cap 3 in threaded connection above the lower bottle stopper 2, a protective cover 5 which is movably connected is arranged on the outer side of the top of the bottle cap 3, an upper bottle stopper 4 is arranged at the center of the bottom of the protective cover 5, the center of the top of the lower bottle stopper 2 is provided with a first boss, the center of the top of the bottle cap 3 is provided with a puncture preformed hole matched with the first boss, go up bottle plug 4 bottom center be equipped with puncture preformed hole assorted second boss, 5 top one side of visor is equipped with the tear line, and the hookup point position of tear line must coincide with inboard labyrinth seal mutually, otherwise the seal structure is incomplete.

The body 1, the bottle cap 3 and the protective cap 5 of the freezing bottle are all made of polymer composite materials (COC), and the material can keep the dimensional stability at extremely low temperature (-196 ℃ and below), so that the low-temperature resistance of the whole structure of the freezing bottle is ensured.

The lower bottle stopper 2 and the upper bottle stopper 4 are both made of special silica gel materials, and the materials can keep the dimensional stability at extremely low temperature (-196 ℃ and below), so that the flexible sealing treatment effect of the sealing structure is ensured.

The lower bottle stopper 2 and the upper bottle stopper 4 are both made of thermoplastic rubber (TPE) materials, and the size stability of the materials can be kept at extremely low temperature (-196 ℃ and below), so that the flexible sealing treatment effect of the sealing structure is ensured.

The bottom of the outer wall of the top opening of the cryopreserved bottle body 1 is provided with first annular skewed teeth, the bottom of the bottle cap 3 is provided with second annular skewed teeth matched with the first annular skewed teeth, the cryopreserved bottle body 1 and the bottle cap 3 are clamped through the first annular skewed teeth and connected together through the second annular skewed teeth, a locking structure is formed, and the connecting effect of the cryopreserved bottle body 1 and the bottle cap 3 is guaranteed.

The outer wall of the opening of the bottle body 1 of the cryopreserved bottle is provided with an external thread, the inner wall of the bottom of the bottle cap 3 is provided with an internal thread matched with the external thread, the bottle body 1 of the cryopreserved bottle is connected with the bottle cap 3 through the thread, and the operation is convenient and rapid.

The top of the bottle cap 3 is provided with an annular bayonet, and the bottom of the protective cover 5 is provided with a clamping finger matched with the annular bayonet, so that the buckling connection mode of the bottle cap 3 and the protective cover 5 is realized.

The bottle cap 3 with be equipped with annular labyrinth seal structure between the visor 5, guarantee the sealing connection effect between bottle cap 3 and the visor 5.

The outer wall of the protective cover 5 is provided with a connecting sheet on one side of the tearing line, the protective cover 5 can be torn along the tearing line by using the connecting sheet, and the operation is more convenient.

The sum of the heights of the first boss and the second boss is equal to the depth of the reserved puncture hole, so that the first boss and the second boss can be simultaneously inserted into the reserved puncture hole.

The implementation mode is specifically as follows: during the use, through setting up freezing bottle body 1, lower bottle plug 2, go up bottle plug 4, bottle lid 3, visor 5, freezing bottle body 1 of depositing: the bottle mouth is provided with threads, the bottle shoulder is designed with a helical tooth structure and is made of transparent COC materials; the lower bottle stopper 2: the sealing element before filling, the first lug boss is used for puncturing and filling medicines besides the positioning function, the edge is pressed by a thread pair between the bottle cap 3 and the frozen bottle body 1, the sealing element is locked by an oblique tooth loose-proof structure and is made of silica gel or TPE (thermoplastic elastomer); and (3) bottle cap: a puncture reserved hole is reserved in the center and used for puncturing a bottle plug, the upper edge of the puncture reserved hole is provided with a circle of bayonet and used for buckling a protective cover 5, the puncture reserved hole is provided with internal threads and used for connecting the frozen bottle body 1, the bottom edge of the inner side of the puncture reserved hole is provided with a circle of helical teeth and used for matching the helical teeth of the frozen bottle body 1 to form a non-loose locking structure, and the puncture reserved hole is made of a colored COC material; and (4) feeding a bottle stopper: the second boss of the filled sealing element is used for positioning, sealing is kept by annular labyrinth sealing between the protective cover 5 and the bottle cap 3 and clamping force of a clamping finger of the protective cover 5, and silica gel or TPE materials are adopted; and (5) a protective cover: the tear line is provided, so that the hand can conveniently open the bottle; the bottle cap 3 is locked by clamping fingers, the number of the clamping fingers is more than 3, and the bottle cap is made of a coloring COC material; the sealing mode of the freezing bottle of the invention is as follows: before filling, the lower bottle plug 2 of the sealing element and the frozen bottle body 1 are pressed and fixed, the bottle cap 3 is screwed, and the edge of the lower bottle plug 2 is pressed by a thread pair between the bottle cap 3 and the frozen bottle body 1 and is locked by the bottle cap 3 and an oblique tooth non-loosening structure of a bottle shoulder to form a first layer of sealing; after filling, an upper bottle stopper 4 of the sealing element is pressed to the upper part of the bottle cap 3 through a protective cover 5, the seal is used for positioning through a second boss of the upper bottle stopper 4, and the seal is kept by the labyrinth seal between the protective cover 5 and the bottle cap 3 and the clamping force of a clamping finger of the protective cover to form a second layer of seal; the protective cover 5 is provided with a tearing line, so that the protective cover is convenient to open by hands; the double-layer sealed cryopreservation bottle has the advantages that the overall dimension of the double-layer sealed cryopreservation bottle is completely consistent with that of the traditional laser sealed cryopreservation bottle, the filling line efficiency is the same, and the main difference is that the sealing modes of the puncture holes are different; the working mode of the double-layer sealed cryopreservation bottle is as follows: before filling, the lower bottle stopper 2, the frozen bottle body 1 and the bottle cap 3 are assembled in advance in a ten thousand-level clean environment (the three parts can form a complete sealing structure); the pre-assembled bottle is placed at a filling station, after the preparation is punctured and filled, an upper bottle stopper 4 of a sealing element is pressed to the upper part of a bottle cap 3 through a protective cover 5, the sealing is used for positioning through a second boss of the upper bottle stopper 4, the sealing is kept by means of labyrinth sealing between the protective cover 5 and the bottle cap 3 and clamping force of a clamping finger of the protective cover, a second layer of complete sealing is formed, meanwhile, a tearing line of a cover tape is protected, and the bottle can be conveniently opened by a hand at normal temperature in the later period; the first layer of sealing structure is provided with a thread anti-loosening structure and is suitable for manual assembly; the second layer of sealing structure is a buckle structure and is suitable for machine pressing assembly.

The working principle of the invention is as follows:

referring to the attached drawings 1-15 of the specification, through arranging the freezing bottle body 1, the lower bottle stopper 2, the upper bottle stopper 4, the bottle cap 3 and the protective cap 5, after the freezing bottle body 1 and the bottle cap 3 are screwed down, the sawtooth-shaped structures of the bottle neck and the bottle cap 3 play a role in preventing looseness, the lower bottle stopper 2 is used for performing head layer sealing between the bottle body 1 and the bottle cap 3, and the upper bottle stopper 4 and the protective cap 5 perform secondary sealing after medicine is injected into the bottle, so that the integrity of sealing is ensured.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.